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Eduardo Sotomayor

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Fengdong Cheng; Pedro Horna; Javier Pinilla-Ibarz; Eva Sahakian; Said Sebti; Bijal Shah; Mitchell Smith; Jianguo Tao; alejandro villagra; Hongwei Wang; Zi Wang; Karrune V Woan; Eduardo M Sotomayor
Stat3 inhibition augments the immunogenicity of B-cell lymphoma cells, leading to effective antitumor immunity.
Fanqi Bai; Michelle A Blaskovich; Kirby Connolly; Julie Y Djeu; Thomas P Loughran; Jeffrey S Painter; Said Sebti; Lubomir Sokol; Eduardo M Sotomayor; Alejandro V Villagra; Sheng Wei; Jianxiang Zou; Pearlie Epling-Burnette
Tipifarnib-mediated suppression of T-bet-dependent signaling pathways.
Jane Jijun Liu; Jose L Ochoa-Bayona; Lia Perez; Jyotishankar Raychaudhuri; Eduardo M Sotomayor; Ling Zhang; Ernesto Ayala; Rachid C Baz; Celeste M Bello; Salvador Bruno; Paul A Chervenick; Jennifer L Cultrera; Teresa Field; Mohamed A Kharfan-Dabaja; Lubomir Sokol
Human immunodeficiency virus (HIV)-negative plasmablastic lymphoma: a single institutional experience and literature review.

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All Publications

2012: Fengdong Cheng; Pedro Horna; Javier Pinilla-Ibarz; Eva Sahakian; Said Sebti; Bijal Shah; Mitchell Smith; Jianguo Tao; alejandro villagra; Hongwei Wang; Zi Wang; Karrune V Woan; Eduardo M Sotomayor
Stat3 inhibition augments the immunogenicity of B-cell lymphoma cells, leading to effective antitumor immunity.
Cancer research 2012;72(17):4440-8.
2012: Fanqi Bai; Michelle A Blaskovich; Kirby Connolly; Julie Y Djeu; Thomas P Loughran; Jeffrey S Painter; Said Sebti; Lubomir Sokol; Eduardo M Sotomayor; Alejandro V Villagra; Sheng Wei; Jianxiang Zou; Pearlie Epling-Burnette
Tipifarnib-mediated suppression of T-bet-dependent signaling pathways.
Cancer immunology, immunotherapy : CII 2012;61(4):523-33.
2011: Jane Jijun Liu; Jose L Ochoa-Bayona; Lia Perez; Jyotishankar Raychaudhuri; Eduardo M Sotomayor; Ling Zhang; Ernesto Ayala; Rachid C Baz; Celeste M Bello; Salvador Bruno; Paul A Chervenick; Jennifer L Cultrera; Teresa Field; Mohamed A Kharfan-Dabaja; Lubomir Sokol
Human immunodeficiency virus (HIV)-negative plasmablastic lymphoma: a single institutional experience and literature review.
Leukemia research 2011;35(12):1571-7.
2011: Rami S Komrokji; Javier Pinilla-Ibarz; Dana Rollison; Malek M Safa; Lubomir Sokol; Najla H Al Ali; M S Beg; Celeste Bello; Jennifer Cultrera; Mohamed Kharfan-Dabaja; Eduardo M Sotomayor
Outcome of diffuse large B-Cell lymphoma in the United States has improved over time but racial disparities remain: review of SEER data.
Clinical lymphoma, myeloma & leukemia 2011;11(3):257-60.
2011: J Lin; T Lwin; J-J Zhao; W Tam; Y S Choi; Lynn Moscinski; William S Dalton; Eduardo M Sotomayor; K L Wright; J Tao
Follicular dendritic cell-induced microRNA-mediated upregulation of PRDM1 and downregulation of BCL-6 in non-Hodgkin's B-cell lymphomas.
Leukemia 2011;25(1):145-52.
2010: Jian-Jun Zhao; Jianhong Lin; Tint Lwin; Hua Yang; Jianping Guo; William Kong; Sophie Dessureault; Lynn Moscinski; Dorna Rezania; William S Dalton; Eduardo M Sotomayor; Jianguo Tao; Jin Q Cheng
microRNA expression profile and identification of miR-29 as a prognostic marker and pathogenetic factor by targeting CDK6 in mantle cell lymphoma.
Blood 2010;115(13):2630-9.
2009: Cesar A Corzo; Matthew J Cotter; Pingyan Cheng; Fendong Cheng; Sergei Kusmartsev; Eduardo M Sotomayor; Tapan Padhya; Thomas V McCaffrey; Judith C McCaffrey; Dmitry I Gabrilovich
Mechanism regulating reactive oxygen species in tumor-induced myeloid-derived suppressor cells.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(9):5693-701.
2009: T Lwin; L A Crespo; A Wu; Sophie Dessureault; H B Shu; Lynn Moscinski; Eduardo M Sotomayor; William S Dalton; J Tao
Lymphoma cell adhesion-induced expression of B cell-activating factor of the TNF family in bone marrow stromal cells protects non-Hodgkin's B lymphoma cells from apoptosis.
Leukemia 2009;23(1):170-7.
2007: alejandro villagra; Natalia Ulloa; Xiaohong Zhang; Zhigang Yuan; Eduardo M Sotomayor; Edward Seto
Histone deacetylase 3 down-regulates cholesterol synthesis through repression of lanosterol synthase gene expression.
The Journal of biological chemistry 2007;282(49):35457-70.
2007: Ildefonso Vicente-Suarez; Yoshinori Takahashi; Fengdong Cheng; Pedro Horna; Hong W Wang; Hong-Gang Wang; Eduardo M Sotomayor
Identification of a novel negative role of flagellin in regulating IL-10 production.
European journal of immunology 2007;37(11):3164-75.
2007: Tint Lwin; Lori A Hazlehurst; Sophie Dessureault; Raymond Lai; Wenlong Bai; Eduardo M Sotomayor; Lynn Moscinski; William S Dalton; Jianguo Tao
Cell adhesion induces p27Kip1-associated cell-cycle arrest through down-regulation of the SCFSkp2 ubiquitin ligase pathway in mantle-cell and other non-Hodgkin B-cell lymphomas.
Blood 2007;110(5):1631-8.
2007: T Lwin; Lori A Hazlehurst; Z Li; Sophie Dessureault; Eduardo M Sotomayor; Lynn Moscinski; William S Dalton; J Tao
Bone marrow stromal cells prevent apoptosis of lymphoma cells by upregulation of anti-apoptotic proteins associated with activation of NF-kappaB (RelB/p52) in non-Hodgkin's lymphoma cells.
Leukemia 2007;21(7):1521-31.
2007: Pedro Horna; Eduardo M Sotomayor
Cellular and molecular mechanisms of tumor-induced T-cell tolerance.
Current cancer drug targets 2007;7(1):41-53.
2007: Sophie Dessureault; David Noyes; David Lee; Mary Dunn; William Janssen; Alan Cantor; Eduardo M Sotomayor; Jane Messina; Scott J Antonia
A phase-I trial using a universal GM-CSF-producing and CD40L-expressing bystander cell line (GM.CD40L) in the formulation of autologous tumor cell-based vaccines for cancer patients with stage IV disease.
Annals of surgical oncology 2007;14(2):869-84.
2007: Gabriel A Rabinovich; Dmitry I Gabrilovich; Eduardo M Sotomayor
Immunosuppressive strategies that are mediated by tumor cells.
Annual review of immunology 2007;25():267-96.
2006: Pedro Horna; Alex Cuenca; Fengdong Cheng; Jason Brayer; Hong-Wei Wang; Ivan Borrello; Hyam I Levitsky; Eduardo M Sotomayor
In vivo disruption of tolerogenic cross-presentation mechanisms uncovers an effective T-cell activation by B-cell lymphomas leading to antitumor immunity.
Blood 2006;107(7):2871-8.
2005: Hongwei Wang; Fengdong Cheng; Alex Cuenca; Pedro Horna; Zheng Zheng; Kapil N Bhalla; Eduardo M Sotomayor
Imatinib mesylate (STI-571) enhances antigen-presenting cell function and overcomes tumor-induced CD4+ T-cell tolerance.
Blood 2005;105(3):1135-43.
2004: Tomar Ghansah; Kim H T Paraiso; Steven Highfill; Caroline Desponts; Sarah May; Joseph K McIntosh; Jia-Wang Wang; John M Ninos; Jason Brayer; Fengdong Cheng; Eduardo M Sotomayor; William G Kerr
Expansion of myeloid suppressor cells in SHIP-deficient mice represses allogeneic T cell responses.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(12):7324-30.
2004: Paulo C Rodriguez; David G Quiceno; Jovanny Zabaleta; Blair Ortiz; Arnold H Zea; M Blanca Piazuelo; Alberto Delgado; Pelayo Correa; Jason Brayer; Eduardo M Sotomayor; Scott J Antonia; Juan B Ochoa; Augusto C Ochoa
Arginase I production in the tumor microenvironment by mature myeloid cells inhibits T-cell receptor expression and antigen-specific T-cell responses.
Cancer research 2004;64(16):5839-49.
2004: Fengdong Cheng; Dmitry I Gabrilovich; Eduardo M Sotomayor
Immune tolerance in breast cancer.
Breast disease 2004;20():93-103.
2003: Alex Cuenca; Fengdong Cheng; Hongwei Wang; Jason Brayer; Pedro Horna; Lingping Gu; Harold Bien; Ivan Borrello; Hyam I Levitsky; Eduardo M Sotomayor
Extra-lymphatic solid tumor growth is not immunologically ignored and results in early induction of antigen-specific T-cell anergy: dominant role of cross-tolerance to tumor antigens.
Cancer research 2003;63(24):9007-15.
2003: Eric Haura; Eduardo M Sotomayor; Scott J Antonia
Gene therapy for lung cancer.
Molecular biotechnology 2003;25(2):139-48.
2003: Fengdong Cheng; Hong-Wei Wang; Alex Cuenca; Mei Huang; Tomar Ghansah; Jason Brayer; William G Kerr; Kiyoshi Takeda; Shizuo Akira; Stephen P Schoenberger; Hua Yu; Richard Jove; Eduardo M Sotomayor
A critical role for Stat3 signaling in immune tolerance.
Immunity 2003;19(3):425-36.
2003: Sergei Kusmartsev; Fengdong Cheng; Bin Yu; Yulia Nefedova; Eduardo M Sotomayor; Richard Lush; Dmitry I Gabrilovich
All-trans-retinoic acid eliminates immature myeloid cells from tumor-bearing mice and improves the effect of vaccination.
Cancer research 2003;63(15):4441-9.
2003: Bin Yu; Sergei Kusmartsev; Fengdong Cheng; Maria Paolini; Yulia Nefedova; Eduardo M Sotomayor; Dmitry I Gabrilovich
Effective combination of chemotherapy and dendritic cell administration for the treatment of advanced-stage experimental breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(1):285-94.
2003: Eric Haura; Eduardo M Sotomayor; Scott J Antonia
Gene therapy for lung cancer. An introduction.
Methods in molecular medicine 2003;75():529-43.
2002: Lyudmila Burdelya; Robyn Catlett-Falcone; Alexander Levitzki; Fengdong Cheng; Linda B Mora; Eduardo M Sotomayor; Domenico Coppola; JiaZhi Sun; Said Sebti; William S Dalton; Richard Jove; Hua Yu
Combination therapy with AG-490 and interleukin 12 achieves greater antitumor effects than either agent alone.
Molecular cancer therapeutics 2002;1(11):893-9.
2002: Ivan Borrello; Eduardo M Sotomayor
Cancer vaccines for hematologic malignancies.
Cancer control : journal of the Moffitt Cancer Center 2002;9(2):138-51.
2002: Maria G Sotomayor; Hua Yu; Scott J Antonia; Eduardo M Sotomayor; Drew M Pardoll
Advances in gene therapy for malignant melanoma.
Cancer control : journal of the Moffitt Cancer Center 2002;9(1):39-48.
2001: Eduardo M Sotomayor; Ivan Borrello; FM Rattis; Alex Cuenca; J Abrams; K Staveley-O'Carroll; Hyam I Levitsky
Cross-presentation of tumor antigens by bone marrow-derived antigen-presenting cells is the dominant mechanism in the induction of T-cell tolerance during B-cell lymphoma progression.
Blood 2001;98(4):1070-7.
2000: Ivan Borrello; Eduardo M Sotomayor; FM Rattis; S K Cooke; L Gu; Hyam I Levitsky
Sustaining the graft-versus-tumor effect through posttransplant immunization with granulocyte-macrophage colony-stimulating factor (GM-CSF)-producing tumor vaccines.
Blood 2000;95(10):3011-9.
2000: Scott J Antonia; Eduardo M Sotomayor
Gene therapy for lung cancer.
Current opinion in oncology 2000;12(2):138-42.
2000: Z Lu; L Yuan; X Zhou; Eduardo M Sotomayor; Hyam I Levitsky; Drew M Pardoll
CD40-independent pathways of T cell help for priming of CD8(+) cytotoxic T lymphocytes.
The Journal of experimental medicine 2000;191(3):541-50.
1999: Eduardo M Sotomayor; Ivan Borrello; E Tubb; J P Allison; Hyam I Levitsky
In vivo blockade of CTLA-4 enhances the priming of responsive T cells but fails to prevent the induction of tumor antigen-specific tolerance.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(20):11476-81.
1999: Ivan Borrello; Eduardo M Sotomayor; S Cooke; Hyam I Levitsky
A universal granulocyte-macrophage colony-stimulating factor-producing bystander cell line for use in the formulation of autologous tumor cell-based vaccines.
Human gene therapy 1999;10(12):1983-91.
1999: Eduardo M Sotomayor; Ivan Borrello; E Tubb; FM Rattis; H Bien; Z Lu; S Fein; Stephen P Schoenberger; Hyam I Levitsky
Conversion of tumor-specific CD4+ T-cell tolerance to T-cell priming through in vivo ligation of CD40.
Nature medicine 1999;5(7):780-7.
1998: K Staveley-O'Carroll; Eduardo M Sotomayor; J Montgomery; Ivan Borrello; L Hwang; S Fein; Drew M Pardoll; Hyam I Levitsky
Induction of antigen-specific T cell anergy: An early event in the course of tumor progression.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(3):1178-83.
1996: Eduardo M Sotomayor; Ivan Borrello; Hyam I Levitsky
Tolerance and cancer: a critical issue in tumor immunology.
Critical reviews in oncogenesis 1996;7(5-6):433-56.