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Pavel Soucek

Research Profile

Chemicals & Drugs

Anatomy

Microsomes, Liver

Physiology

Disorders

Procedures

Living Beings

Geographic Areas

Czech Republic

Genes & Molecular Sequences

Single Nucleotide Polymorphism

Co-author Network

Publications

TOP 3
Radka Vaclavikova; Marketa Trnkova; Jan Adamek; Hege Edvardsen; Marie Ehrlichova; Ivan Gut; Ivona Hlavata; Renata Kozevnikovova; Vessela N Kristensen; Vaclav Pecha; Pavel Soucek
Detection of frequent ABCB1 polymorphisms by high-resolution melting curve analysis and their effect on breast carcinoma prognosis.
I Hlavata; Lubos Holubec; V Liska; B Mohelnikova-Duchonova; P Novak; P Pitule; V Treska; Radka Vaclavikova; Pavel Vodicka; O Vycital; J Bruha; Pavel Soucek
The role of ABC transporters in progression and clinical outcome of colorectal cancer.
Ondrej Havranek; Petr Hubacek; Katerina Benesova; Heidi Mocikova; Pavel Soucek; Martin Spacek; Marek Trneny; Zdenek Kleibl
No association between the TP53 codon 72 polymorphism and risk or prognosis of Hodgkin and non-Hodgkin lymphoma.

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All Publications

2012: Radka Vaclavikova; Marketa Trnkova; Jan Adamek; Hege Edvardsen; Marie Ehrlichova; Ivan Gut; Ivona Hlavata; Renata Kozevnikovova; Vessela N Kristensen; Vaclav Pecha; Pavel Soucek
Detection of frequent ABCB1 polymorphisms by high-resolution melting curve analysis and their effect on breast carcinoma prognosis.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2012;50(11):1999-2007.
2012: I Hlavata; Lubos Holubec; V Liska; B Mohelnikova-Duchonova; P Novak; P Pitule; V Treska; Radka Vaclavikova; Pavel Vodicka; O Vycital; J Bruha; Pavel Soucek
The role of ABC transporters in progression and clinical outcome of colorectal cancer.
Mutagenesis 2012;27(2):187-96.
2011: Ondrej Havranek; Petr Hubacek; Katerina Benesova; Heidi Mocikova; Pavel Soucek; Martin Spacek; Marek Trneny; Zdenek Kleibl
No association between the TP53 codon 72 polymorphism and risk or prognosis of Hodgkin and non-Hodgkin lymphoma.
Leukemia research 2011;35(8):1117-9.
2011: Pavel Soucek; Eliska Kondrova; Josef Hermanek; Pavel Stopka; Ahcène Boumendjel; Yune-Fang Ueng; Ivan Gut
New model system for testing effects of flavonoids on doxorubicin-related formation of hydroxyl radicals.
Anti-cancer drugs 2011;22(2):176-84.
2011: Beatrice Mohelnikova-Duchonova; Lenka Marsakova; David Vrana; Ivana Holcatova; Miroslav Ryska; Zdenek Smerhovsky; Alena Slamova; Miriam Schejbalova; Pavel Soucek
Superoxide dismutase and nicotinamide adenine dinucleotide phosphate: quinone oxidoreductase polymorphisms and pancreatic cancer risk.
Pancreas 2011;40(1):72-8.
2011: Monika Hanova; Ludmila Vodickova; Radka Vaclavikova; Zdenek Smerhovsky; Rudolf Stetina; Pavel Hlavac; Alessio Naccarati; Jana Slyskova; Veronika Polakova; Pavel Soucek; Rajiv Kumar; Kari Hemminki; Pavel Vodicka
DNA damage, DNA repair rates and mRNA expression levels of cell cycle genes (TP53, p21(CDKN1A), BCL2 and BAX) with respect to occupational exposure to styrene.
Carcinogenesis 2011;32(1):74-9.
2010: Ivona Hlavata; David Vrana; Zdenek Smerhovsky; Barbara Pardini; Alessio Naccarati; Pavel Vodicka; Jan Novotny; Beatrice Mohelnikova-Duchonova; Pavel Soucek
Association between exposure-relevant polymorphisms in CYP1B1, EPHX1, NQO1, GSTM1, GSTP1 and GSTT1 and risk of colorectal cancer in a Czech population.
Oncology reports 2010;24(5):1347-53.
2010: Monika Hanova; Rudolf Stetina; Ludmila Vodickova; Radka Vaclavikova; Pavel Hlavac; Zdenek Smerhovsky; Alessio Naccarati; Veronika Polakova; Pavel Soucek; Miroslava Kuricova; Paola Manini; Rajiv Kumar; Kari Hemminki; Pavel Vodicka
Modulation of DNA repair capacity and mRNA expression levels of XRCC1, hOGG1 and XPC genes in styrene-exposed workers.
Toxicology and applied pharmacology 2010;248(3):194-200.
2010: Beatrice Mohelnikova-Duchonova; Ondrej Havranek; Ivona Hlavata; Lenka Foretova; Zdenek Kleibl; Petr Pohlreich; Pavel Soucek
CHEK2 gene alterations in the forkhead-associated domain, 1100delC and del5395 do not modify the risk of sporadic pancreatic cancer.
Cancer epidemiology 2010;34(5):656-8.
2010: Alessio Naccarati; Barbara Pardini; V Polakova; Z Smerhovsky; Ludmila Vodickova; Pavel Soucek; D Vrana; I Holcatova; M Ryska; Pavel Vodicka
Genotype and haplotype analysis of TP53 gene and the risk of pancreatic cancer: an association study in the Czech Republic.
Carcinogenesis 2010;31(4):666-70.
2010: Beatrice Mohelnikova-Duchonova; David Vrana; Ivana Holcatova; Miroslav Ryska; Zdenek Smerhovsky; Pavel Soucek
CYP2A13, ADH1B, and ADH1C gene polymorphisms and pancreatic cancer risk.
Pancreas 2010;39(2):144-8.
2009: D Vrana; H Pikhart; B Mohelnikova-Duchonova; Ivana Holcatova; R Strnad; A Slamova; M Schejbalova; M Ryska; S Susova; Pavel Soucek
The association between glutathione S-transferase gene polymorphisms and pancreatic cancer in a central European Slavonic population.
Mutation research 2009;680(1-2):78-81.
2009: Pavel Vodicka; Alessio Naccarati; Ludmila Vodickova; Veronika Polakova; Maria Dusinska; Ludovit Musak; Erika Halasova; Simona Susova; Pavel Soucek; Kari Hemminki
Do GST polymorphisms modulate the frequency of chromosomal aberrations in healthy subjects?
Environmental health perspectives 2009;117(9):A384-5; author reply A385.
2009: Miluse Hubackova; Radka Vaclavikova; Marcela Mrhalova; Katerina Kubackova; Roman Kodet; Ivan Gut; Pavel Soucek
NAD(P)H:quinone oxidoreductase 1 Pro187Ser polymorphism and expression do not cosegregate with clinico-pathological characteristics of human mammary tumors.
Pharmacogenetics and genomics 2009;19(7):505-12.
2009: Barbara Pardini; Alessio Naccarati; Veronika Polakova; Zdenek Smerhovsky; Ivona Hlavata; Pavel Soucek; Jan Novotny; Ludmila Vodickova; Vera Tomanova; Stefano Landi; Pavel Vodicka
NBN 657del5 heterozygous mutations and colorectal cancer risk in the Czech Republic.
Mutation research 2009;666(1-2):64-7.
2009: Zdenek Kleibl; Ondrej Havranek; Ivona Hlavata; Jan Novotny; Jan Sevcik; Petr Pohlreich; Pavel Soucek
The CHEK2 gene I157T mutation and other alterations in its proximity increase the risk of sporadic colorectal cancer in the Czech population.
European journal of cancer (Oxford, England : 1990) 2009;45(4):618-24.
2008: Zdenek Kleibl; Ondrej Havranek; Jan Novotny; Petra Kleiblova; Pavel Soucek; Petr Pohlreich
Analysis of CHEK2 FHA domain in Czech patients with sporadic breast cancer revealed distinct rare genetic alterations.
Breast cancer research and treatment 2008;112(1):159-64.
2008: Ludovit Musak; Pavel Soucek; Ludmila Vodickova; Alessio Naccarati; Erika Halasova; Veronika Polakova; Jana Slyskova; Simona Susova; Janka Buchancova; Zdenek Smerhovsky; Jana Sedikova; Gabriela Klimentova; Oto Osina; Kari Hemminki; Pavel Vodicka
Chromosomal aberrations in tire plant workers and interaction with polymorphisms of biotransformation and DNA repair genes.
Mutation research 2008;641(1-2):36-42.
2008: Radka Vaclavikova; Silje H Nordgard; Grethe I G Alnaes; Miluse Hubackova; Eugen Kubala; Roman Kodet; Marcela Mrhalova; Jan Novotny; Ivan Gut; Vessela N Kristensen; Pavel Soucek
Single nucleotide polymorphisms in the multidrug resistance gene 1 (ABCB1): effects on its expression and clinicopathological characteristics in breast cancer patients.
Pharmacogenetics and genomics 2008;18(3):263-73.
2008: Radka Václavíková; Eliska Kondrová; Marie Ehrlichová; Ahcène Boumendjel; Jan Kovár; Pavel Stopka; Pavel Soucek; Ivan Gut
The effect of flavonoid derivatives on doxorubicin transport and metabolism.
Bioorganic & medicinal chemistry 2008;16(4):2034-42.
2007: J Slyskova; Maria Dusinska; Miroslava Kuricova; Pavel Soucek; Ludmila Vodickova; S Susova; Alessio Naccarati; Elena Tulupova; Pavel Vodicka
Relationship between the capacity to repair 8-oxoguanine, biomarkers of genotoxicity and individual susceptibility in styrene-exposed workers.
Mutation research 2007;634(1-2):101-11.
2007: Radka Vaclavikova; Miluse Hubackova; Jana Stribrna-Sarmanova; Roman Kodet; Marcela Mrhalova; Jan Novotny; Ivan Gut; Pavel Soucek
RNA expression of cytochrome P450 in breast cancer patients.
Anticancer research 2007;27(6C):4443-50.
2007: Eliska Kondrová; Pavel Stopka; Pavel Soucek
Cytochrome P450 destruction by benzene metabolites 1,4-benzoquinone and 1,4-hydroquinone and the formation of hydroxyl radicals in minipig liver microsomes.
Toxicology in vitro : an international journal published in association with BIBRA 2007;21(4):566-75.
2007: Pavel Vodicka; Rudolf Stetina; Veronika Polakova; Elena Tulupova; Alessio Naccarati; Ludmila Vodickova; Rajiv Kumar; Monika Hanova; Barbara Pardini; Jana Slyskova; Ludovit Musak; giuseppe de palma; Pavel Soucek; Kari Hemminki
Association of DNA repair polymorphisms with DNA repair functional outcomes in healthy human subjects.
Carcinogenesis 2007;28(3):657-64.
2007: Valentina Paracchini; Sara Raimondi; Inger Torhild Gram; Daehee Kang; Neslihan A Kocabas; Vessela N Kristensen; Donghui Li; Fritz F Parl; Tove Rylander-Rudqvist; Pavel Soucek; Wei Zheng; Sara Wedren; Emanuela Taioli
Meta- and pooled analyses of the cytochrome P-450 1B1 Val432Leu polymorphism and breast cancer: a HuGE-GSEC review.
American journal of epidemiology 2007;165(2):115-25.
2007: J Krásný; Ilona Cihelková; Z Domínek; Pavel Soucek; L Treslová; Jan Lebl; M Andĕl
[Contrast sensitivity and fluorescein angiography in evaluating the ocular changes in the relation to the diabetes mellitus type I compensation in young adult patients].
Ceská a slovenská oftalmologie : casopis Ceské oftalmologické spolecnosti a Slovenské oftalmologické spolecnosti 2007;63(1):17-27.
2006: Ilona Cihelkova; Pavel Soucek; Josef Sach
Uveal melanoma in congenital ocular melanocytosis mimicking malignant transformation of the optic disc melanocytoma (a controlled case).
Neuro endocrinology letters 2006;27(6):729-32.
2006: Pavel Soucek; Ilona Cihelkova
Photodynamic therapy with Verteporfin in subfoveal choroidal metastasis of breast carcinoma (a controlled case).
Neuro endocrinology letters 2006;27(6):725-8.
2006: L'udovít Musák; Pavel Vodicka; Gabriela Klimentová; Pavel Soucek; Monika Hánová; Renáta Mikulková; Janka Buchancová; Ludmila Vodicková; Veronika Poláková; Martin Péc
Chromosomal damage and polymorphisms of DNA repair genes XRCC1 and XRCC3 in workers exposed to cytostatics.
Neuro endocrinology letters 2006;27 Suppl 2():57-60.
2006: Berta Otová; Radka Václavíková; Vlasta Danielová; Jaroslava Holubová; Marie Ehrlichová; Stanislav Horský; Pavel Soucek; Petr Simek; Ivan Gut
Effects of paclitaxel, docetaxel and their combinations on subcutaneous lymphomas in inbred Sprague-Dawley/Cub rats.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2006;29(5):442-50.
2006: Ivan Gut; I Ojima; Radka Vaclavikova; Petr Simek; S Horsky; Igor Linhart; Pavel Soucek; E Kondrova; Larisa V Kuznetsova; J Chen
Metabolism of new-generation taxanes in human, pig, minipig and rat liver microsomes.
Xenobiotica; the fate of foreign compounds in biological systems 2006;36(9):772-92.
2006: Pavel Soucek; Ilona Cihelkova
Primary treatment of choroidal amelanotic melanoma with photodynamic therapy--comment.
Clinical & experimental ophthalmology 2006;34(7):721; author reply 721-2.
2006: Marie Stiborová; Helena Dracínská; Jana Hájková; Pavla Kaderábková; Eva Frei; Heinz H Schmeiser; Pavel Soucek; David H Phillips; Volker M Arlt
The environmental pollutant and carcinogen 3-nitrobenzanthrone and its human metabolite 3-aminobenzanthrone are potent inducers of rat hepatic cytochromes P450 1A1 and -1A2 and NAD(P)H:quinone oxidoreductase.
Drug metabolism and disposition: the biological fate of chemicals 2006;34(8):1398-405.
2006: Simona Susova; Marek Trneny; Pavel Soucek
Single nucleotide polymorphism in 5'-flanking region of BCL6 is not associated with increased risk of non-Hodgkin's lymphoma.
Cancer letters 2006;238(1):142-5.
2006: Ilona Cihelková; Pavel Soucek; Josef Sach
[Optical coherence tomography in pars plana vitrectomy for idiopathic macular hole].
Ceská a slovenská oftalmologie : casopis Ceské oftalmologické spolecnosti a Slovenské oftalmologické spolecnosti 2006;62(2):100-9.
2006: Pavel Soucek; Ilona Cihelkova
Photodynamic therapy with verteporfin in subfoveal amelanotic choroidal melanoma (A controlled case).
Neuro endocrinology letters 2006;27(1-2):145-8.
2006: Alessio Naccarati; Pavel Soucek; Rudolf Stetina; Vincent Haufroid; Rajiv Kumar; Ludmila Vodickova; Katerina Trtkova; Maria Dusinska; Kari Hemminki; Pavel Vodicka
Genetic polymorphisms and possible gene-gene interactions in metabolic and DNA repair genes: effects on DNA damage.
Mutation research 2006;593(1-2):22-31.
2005: Pavel Soucek; Pavel Anzenbacher; Ivana Skoumalová; Michal Dvorák
Expression of cytochrome P450 genes in CD34+ hematopoietic stem and progenitor cells.
Stem cells (Dayton, Ohio) 2005;23(9):1417-22.
2005: Jana Baranová; Eva Anzenbacherová; Pavel Anzenbacher; Pavel Soucek
Minipig cytochrome P450 2E1: comparison with human enzyme.
Drug metabolism and disposition: the biological fate of chemicals 2005;33(6):862-5.
2005: Mohammad Azab; David S Boyer; Neil M Bressler; Susan B Bressler; Ilona Cihelkova; Young Hao; Ilkka Immonen; Jennifer I Lim; Ugo Menchini; Joel Naor; Michael J Potter; Al Reaves; Philip J Rosenfeld; Jason S Slakter; Pavel Soucek; H Andrew Strong; Andrea Wenkstern; Xiang Yao Su; Yit C Yang
Verteporfin therapy of subfoveal minimally classic choroidal neovascularization in age-related macular degeneration: 2-year results of a randomized clinical trial.
Archives of ophthalmology 2005;123(4):448-57.
2005: Eva Anzenbacherová; Jana Baranová; Roman Zuber; Alena Pechová; Pavel Anzenbacher; Pavel Soucek; Jirina Martínková
Model systems based on experimental animals for studies on drug metabolism in man: (mini)pig cytochromes P450 3A29 and 2E1.
Basic & clinical pharmacology & toxicology 2005;96(3):244-5.
2004: Pavel Soucek; Camilla Furu Skjelbred; Martin Veel Svendsen; Tom Kristensen; Elin H Kure; Vessela N Kristensen
Single-track sequencing for genotyping of multiple SNPs in the N-acetyltransferase 1 (NAT1) gene.
BMC biotechnology 2004;4():28.
2004: Jana Sarmanová; Simona Sůsová; Ivan Gut; Marcela Mrhalová; Roman Kodet; Jan Adámek; Zdenek Roth; Pavel Soucek
Breast cancer: role of polymorphisms in biotransformation enzymes.
European journal of human genetics : EJHG 2004;12(10):848-54.
2004: Pavel Soucek; Ilona Cihelková; Josef Sach
[Diseases of the vitreoretinal region. Part II].
Ceská a slovenská oftalmologie : casopis Ceské oftalmologické spolecnosti a Slovenské oftalmologické spolecnosti 2004;60(5):373-7.
2004: Radka Vaclavikova; Pavel Soucek; Lenka Svobodova; Pavel Anzenbacher; Petr Simek; F Peter Guengerich; Ivan Gut
Different in vitro metabolism of paclitaxel and docetaxel in humans, rats, pigs, and minipigs.
Drug metabolism and disposition: the biological fate of chemicals 2004;32(6):666-74.
2004: HJ Menzel; J Sarmanova; Pavel Soucek; R Berberich; Kurt Grünewald; Margot Haun; Hans Georg Kraft
Association of NQO1 polymorphism with spontaneous breast cancer in two independent populations.
British journal of cancer 2004;90(10):1989-94.
2004: Ilona Cihelková; Pavel Soucek
[Diseases of the vitreoretinal junction. Part I].
Ceská a slovenská oftalmologie : casopis Ceské oftalmologické spolecnosti a Slovenské oftalmologické spolecnosti 2004;60(3):216-20.
2004: Pavel Vodicka; Rajiv Kumar; Rudolf Stetina; Somali Sanyal; Pavel Soucek; Vincent Haufroid; Maria Dusinska; Miroslava Kuricova; Maria Zamecnikova; Ludovit Musak; Jana Buchancova; Hannu Norppa; Ari Hirvonen; Ludmila Vodickova; Alessio Naccarati; Zora Matousu; Kari Hemminki
Genetic polymorphisms in DNA repair genes and possible links with DNA repair rates, chromosomal aberrations and single-strand breaks in DNA.
Carcinogenesis 2004;25(5):757-63.
2004: Pavel Soucek; Ilona Cihelková
Evaluation of subretinal fluid absorption by optical coherence tomography in circumscribed choroidal hemangioma after photodynamic therapy with Verteporfin.
Neuro endocrinology letters 2004;25(1-2):109-14.
2004: Pavel Vodicka; Rajiv Kumar; Rudolf Stetina; Ludovit Musak; Pavel Soucek; Vincent Haufroid; Maria Sasiadek; Ludmila Vodickova; Alessio Naccarati; Jana Sedikova; Somali Sanyal; Miroslava Kuricova; Viliam Brsiak; Hannu Norppa; Jana Buchancova; Kari Hemminki
Markers of individual susceptibility and DNA repair rate in workers exposed to xenobiotics in a tire plant.
Environmental and molecular mutagenesis 2004;44(4):283-92.
2003: Pavel Soucek; Jaroslav Havlícek; Marcela Tkadlecová; Ivan Karel; Karel Volka; Ilona Cihelková
The function of the blood aqueous barrier in eyes with emulsified silicone oil.
Neuro endocrinology letters 2003;24(6):454-8.
2003: Ilona Cihelková; Pavel Soucek
[ Findings on optical coherence tomography in patients with macular degeneration treated with photodynamic therapy using Visudyne].
Ceská a slovenská oftalmologie : casopis Ceské oftalmologické spolecnosti a Slovenské oftalmologické spolecnosti 2003;59(4):250-6.
2003: Pavel Soucek; Ivan Gut; Marek Trneny; Eva Skovlund; Grethe Grenaker Alnaes; Tom Kristensen; Anne-Lise Børresen-Dale; Vessela N Kristensen
Multiplex single-tube screening for mutations in the Nijmegen Breakage Syndrome (NBS1) gene in Hodgkin's and non-Hodgkin's lymphoma patients of Slavic origin.
European journal of human genetics : EJHG 2003;11(5):416-9.
2003: Pavel Vodicka; Mikko Koskinen; Rudolf Stetina; Pavel Soucek; Ludmila Vodickova; Z Matousu; Miroslava Kuricova; Kari Hemminki
The role of various biomarkers in the evaluation of styrene genotoxicity.
Cancer detection and prevention 2003;27(4):275-84.
2002: Pavel Soucek; Jana Sarmanová; Vessela N Kristensen; M Apltauerová; Ivan Gut
Genetic polymorphisms of biotransformation enzymes in patients with Hodgkin's and non-Hodgkin's lymphomas.
International archives of occupational and environmental health 2002;75 Suppl():S86-92.
2002: Pavel Vodicka; Rudolf Stetina; Mikko Koskinen; Pavel Soucek; Ludmila Vodicková; Pavel Hlavác; Miroslava Kuricová; Radka Necasová; Kari Hemminki
New aspects in the biomonitoring of occupational exposure to styrene.
International archives of occupational and environmental health 2002;75 Suppl():S75-85.
2002: Pavel Soucek; Ilona Cihelková
Treatment of macular degeneration (a controlled case).
Neuro endocrinology letters 2002;23(4):370-2.
2002: Pavel Soucek; J Boguzsaková; Ilona Cihelková
[Photodynamic therapy with Visudyne in macular degeneration associated with subfoveal classical choroidal neovascularization].
Ceská a slovenská oftalmologie : casopis Ceské oftalmologické spolecnosti a Slovenské oftalmologické spolecnosti 2002;58(2):89-97.
2002: Pavel Anzenbacher; Eva Anzerbacherová; Roman Zuber; Pavel Soucek; F Peter Guengerich
Pig and minipig cytochromes P450.
Drug metabolism and disposition: the biological fate of chemicals 2002;30(1):100-2.
2001: Pavel Vodicka; Pavel Soucek; Ad D Tates; Maria Dusinska; J Sarmanova; M Zamecnikova; Ludmila Vodickova; Mikko Koskinen; Franz A de Zwart; Adayapalam T Natarajan; Kari Hemminki
Association between genetic polymorphisms and biomarkers in styrene-exposed workers.
Mutation research 2001;482(1-2):89-103.
2001: Jana Sarmanová; K Benesová; Ivan Gut; V Nedelcheva-Kristensen; L Tynková; Pavel Soucek
Genetic polymorphisms of biotransformation enzymes in patients with Hodgkin's and non-Hodgkin's lymphomas.
Human molecular genetics 2001;10(12):1265-73.
2001: Pavel Soucek; I Gut
Effect of the microsomal system on quinone redox cycling, oxygen activation, and lipid peroxidation.
Advances in experimental medicine and biology 2001;500():351-4.
2001: Pavel Soucek; Roman Zuber; Eva Anzenbacherová; Pavel Anzenbacher; F P Guengerich
Minipig cytochrome P450 3A, 2A and 2C enzymes have similar properties to human analogs.
BMC pharmacology 2001;1():11.
2000: Jana Sarmanová; L Tynková; S Süsová; Ivan Gut; Pavel Soucek
Genetic polymorphisms of biotransformation enzymes: allele frequencies in the population of the Czech Republic.
Pharmacogenetics 2000;10(9):781-8.
2000: I Gut; Vlasta Danielová; Jaroslava Holubová; Pavel Soucek; H Klucková
Cytotoxicity of cyclophosphamide, paclitaxel, and docetaxel for tumor cell lines in vitro: effects of concentration, time and cytochrome P450-catalyzed metabolism.
Archives of toxicology 2000;74(8):437-46.
2000: Eva Anzenbacherová; Nicole Bec; Pavel Anzenbacher; Jirí Hudecek; Pavel Soucek; Christiane Jung; A W Munro; Reinhard Lange
Flexibility and stability of the structure of cytochromes P450 3A4 and BM-3.
European journal of biochemistry / FEBS 2000;267(10):2916-20.
2000: Pavel Soucek; G Ivan; S Pavel
Effect of the microsomal system on interconversions between hydroquinone, benzoquinone, oxygen activation, and lipid peroxidation.
Chemico-biological interactions 2000;126(1):45-61.
1999: Pavel Vodicka; T Tvrdik; S Osterman-Golkar; Ludmila Vodicková; K Peterková; Pavel Soucek; Jana Sarmanová; P B Farmer; Fredrik Granath; B Lambert; Kari Hemminki
An evaluation of styrene genotoxicity using several biomarkers in a 3-year follow-up study of hand-lamination workers.
Mutation research 1999;445(2):205-24.
1999: Pavel Soucek
Cytochrome P450 destruction by quinones: comparison of effects in rat and human liver microsomes.
Chemico-biological interactions 1999;121(3):223-36.
1999: M Somorovská; Eva Jahnová; Jana Tulinská; M Zámecníková; Jana Sarmanová; A Terenová; Ludmila Vodicková; A Lísková; B Vallová; Pavel Soucek; Kari Hemminki; Hannu Norppa; A Hirvonen; Ad D Tates; Laurence Fuortes; Mária Dusinská; Pavel Vodicka
Biomonitoring of occupational exposure to styrene in a plastics lamination plant.
Mutation research 1999;428(1-2):255-69.
1999: V Nedelcheva; I Gut; Pavel Soucek; B Tichavská; L Týnkova; J Mráz; F P Guengerich; M Ingelman-Sundberg
Metabolism of benzene in human liver microsomes: individual variations in relation to CYP2E1 expression.
Archives of toxicology 1999;73(1):33-40.
1998: V Nedelcheva; I Gut; Pavel Soucek; E Frantík
Cytochrome P450 catalyzed oxidation of monochlorobenzene, 1,2- and 1,4-dichlorobenzene in rat, mouse, and human liver microsomes.
Chemico-biological interactions 1998;115(1):53-70.
1998: Pavel Anzenbacher; Pavel Soucek; Eva Anzenbacherová; I Gut; K Hrubý; Zbynek Svoboda; J Kvĕtina
Presence and activity of cytochrome P450 isoforms in minipig liver microsomes. Comparison with human liver samples.
Drug metabolism and disposition: the biological fate of chemicals 1998;26(1):56-9.
1997: Ivan Karel; Bohdana Kalvodová; Martin Filipec; E Bohácová; Pavel Soucek; Ctibor Povýsil; Jirí Vacík; M Tlustáková
Poly (triethylenglycol monomethacrylate) and poly (glycerol monomethacrylate) cross-linked gel as potential viscoelastics for intraoperative use.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1997;235(3):186-9.
1996: I Gut; V Nedelcheva; Pavel Soucek; P Stopka; B Tichavská
Cytochromes P450 in benzene metabolism and involvement of their metabolites and reactive oxygen species in toxicity.
Environmental health perspectives 1996;104 Suppl 6():1211-8.
1996: I Gut; V Nedelcheva; Pavel Soucek; P Stopka; Pavel Vodicka; H V Gelboin; M Ingelman-Sundberg
The role of CYP2E1 and 2B1 in metabolic activation of benzene derivatives.
Archives of toxicology 1996;71(1-2):45-56.
1996: Pavel Soucek; Z Guo; P Sandhu; M V Martin; J Cosme; Philippe Beaune; F P Guengerich
Identification of the highly polymorphic S-mephenytoin hydroxylase in humans.
Archives of toxicology. Supplement. = Archiv für Toxikologie. Supplement 1996;18():437.
1994: Pavel Soucek; B Filipcova; I Gut
Cytochrome P450 destruction and radical scavenging by benzene and its metabolites. Evidence for the key role of quinones.
Biochemical pharmacology 1994;47(12):2233-42.
1993: Pavel Soucek; I Gut
[What is cytochrome P-450? Enzyme forms of cytochrome P-450--extent of knowledge].
Casopís lékar̆ů c̆eských 1993;132(12):353-8.
1993: I Gut; Ylva Terelius; E Frantík; Igor Linhart; Pavel Soucek; B Filipcová; H Klucková
Exposure to various benzene derivatives differently induces cytochromes P450 2B1 and P450 2E1 in rat liver.
Archives of toxicology 1993;67(4):237-43.
1992: Pavel Soucek; I Gut
Cytochromes P-450 in rats: structures, functions, properties and relevant human forms.
Xenobiotica; the fate of foreign compounds in biological systems 1992;22(1):83-103.