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William Southerland

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TOP 3
Jack Z Hu; Li Bai; Da-Gang Chen; Qi-Tai Xu; William M Southerland
Computational investigation of the anti-HIV activity of Chinese medicinal formula Three-Huang Powder.
Yuan Zhao; Yubin Hao; Hongguang Ji; Yayin Fang; Yinhan Guo; Wei Sha; YANFEI ZHOU; XIAOWU PANG; William M Southerland; Joseph A Califano; Xinbin Gu
Combination effects of salvianolic acid B with low-dose celecoxib on inhibition of head and neck squamous cell carcinoma growth in vitro and in vivo.
Zengjian Hu; Dagang Chen; Lanxiang Dong; William M Southerland
Prediction of the interaction of HIV-1 integrase and its dicaffeoylquinic acid inhibitor through molecular modeling approach.

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All Publications

2010: Jack Z Hu; Li Bai; Da-Gang Chen; Qi-Tai Xu; William M Southerland
Computational investigation of the anti-HIV activity of Chinese medicinal formula Three-Huang Powder.
Interdisciplinary sciences, computational life sciences 2010;2(2):151-6.
2010: Yuan Zhao; Yubin Hao; Hongguang Ji; Yayin Fang; Yinhan Guo; Wei Sha; YANFEI ZHOU; XIAOWU PANG; William M Southerland; Joseph A Califano; Xinbin Gu
Combination effects of salvianolic acid B with low-dose celecoxib on inhibition of head and neck squamous cell carcinoma growth in vitro and in vivo.
Cancer prevention research (Philadelphia, Pa.) 2010;3(6):787-96.
2010: Zengjian Hu; Dagang Chen; Lanxiang Dong; William M Southerland
Prediction of the interaction of HIV-1 integrase and its dicaffeoylquinic acid inhibitor through molecular modeling approach.
Ethnicity & disease 2010;20(1 Suppl 1):S1-45-9.
2009: Zeng-Jian Hu; Li Bai; Yousef Tizabi; William M Southerland
Computational modeling study of human nicotinic acetylcholine receptor for developing new drugs in the treatment of alcoholism.
Interdisciplinary sciences, computational life sciences 2009;1(4):254-62.
2007: Jharna Das; Elizabeth B Fryar-Tita; YANFEI ZHOU; Sidney Green; William M Southerland; Donnell Bowen
Sequence-dependent administration of 5-fluorouracil maintains methotrexate antineoplastic activity in human estrogen-negative breast cancer and protects against methotrexate cytotoxicity in human bone marrow.
Anticancer research 2007;27(6B):3791-9.
2007: Zengjian Hu; Donnell Bowen; William M Southerland; Antonio del Sol; Yongping Pan; Ruth Nussinov; Buyong Ma
Ligand binding and circular permutation modify residue interaction network in DHFR.
PLoS computational biology 2007;3(6):e117.
2007: Elizabeth B Fryar-Tita; Jharna Das; Jillian H Davis; Joseph A Desoto; Sidney Green; William M Southerland; Donnell Bowen
Raloxifene and selective cell cycle specific agents: a case for the inclusion of raloxifene in current breast cancer treatment therapies.
Anticancer research 2007;27(3B):1393-9.
2007: Jharna Das; Elizabeth B Fryar-Tita; Sidney Green; William M Southerland; Donnell Bowen
Sequence-dependent administration of raloxifene and 5-fluorouracil/pemetrexed protects against pemetrexed cytotoxicity in human bone marrow.
Anticancer research 2007;27(2):825-33.
2007: Jillian H Davis; Joseph A Desoto; Elizabeth B Fryar; William M Southerland; Donnell Bowen
Sequential combination chemotherapy in human breast cancer: a basis for increased antineoplastic activity and bone marrow protection.
Cellular and molecular biology (Noisy-le-Grand, France) 2007;53(3):18-26.
2006: Jharna Das; Elizabeth B Fryar; Sidney Green; William M Southerland; Donnell Bowen
The protection against trimetrexate cytotoxicity in human bone marrow by sequence-dependent administration of raloxifene, 5-fluorouracil/trimetrexate.
Anticancer research 2006;26(6B):4279-86.
2006: Jharna Das; Elizabeth B Fryar; Nicolas N Epie; William M Southerland; Donnell Bowen
Raloxifene attenuation of methotrexate cytotoxicity in human bone marrow by sequence-dependent administration of raloxifene, 5-FU/methotrexate.
Anticancer research 2006;26(3A):1877-83.
2006: Elizabeth B Fryar; Jharna Das; Jillian H Davis; Joseph A Desoto; Ibrahim Laniyan; William M Southerland; Donnell Bowen
Raloxifene attenuation of 5-FU/methotrexate cytotoxicity in human breast cancer cells: the importance of sequence in combination chemotherapy.
Anticancer research 2006;26(3A):1861-7.
2006: Jian Yin; Donnell Bowen; William M Southerland
Barnase thermal titration via molecular dynamics simulations: detection of early denaturation sites.
Journal of molecular graphics & modelling 2006;24(4):233-43.
2003: Joseph A Desoto; Donnell Bowen; William M Southerland; M Hawkins; Elizabeth B Fryar; Jillian H Davis
The interaction of the steroidal antagonist faslodex and methotrexate.
Cellular and molecular biology (Noisy-le-Grand, France) 2003;49(7):1067-9.
2002: Joseph A De Soto; Donnell Bowen; Jillian H Davis; William M Southerland; Morris Hawkins
Sequence- and time-dependent antagonism between raloxifene and methotrexate in human breast cancer cells.
Anticancer research 2002;22(2A):1007-9.
2000: Donnell Bowen; William M Southerland; Morris Hawkins; DH Johnson
Sequence-dependent antagonism between tamoxifen and methotrexate in human breast cancer cells.
Anticancer research 2000;20(3A):1415-7.
2000: Donnell Bowen; William M Southerland; DH Johnson; Morris Hawkins; DE Hughes
Implications for improved high-dose methotrexate therapeutic effects in cultured human breast cancer and bone marrow cells.
Cancer detection and prevention 2000;24(5):452-8.
2000: C Pitts; Donnell Bowen; William M Southerland
Interaction energy analyses of folate analog binding to human dihydrofolate reductase: contribution of the antifolate substructural regions to complex stability.
Drug metabolism and drug interactions 2000;16(2):99-121.
1999: R Pan; Donnell Bowen; William M Southerland
Molecular modelling of trimethoprim complexes of human wild-type and mutant dihydrofolate reductases: identification of two subsets of binding residues in the antifolate binding site.
Biopharmaceutics & drug disposition 1999;20(7):335-40.
1999: Donnell Bowen; DH Johnson; William M Southerland; DE Hughes; Morris Hawkins
Selectivity in human breast cancer and human bone marrow using trimetrexate in combination with 5-fluorouracil.
Anticancer research 1999;19(5B):3837-40.
1999: Donnell Bowen; DH Johnson; William M Southerland; DE Hughes; Morris Hawkins
5-Fluorouracil simultaneously maintains methotrexate antineoplastic activity in human breast cancer and protects against methotrexate cytotoxicity in human bone marrow.
Anticancer research 1999;19(2A):985-8.
1997: Donnell Bowen; William M Southerland; C D Bowen; DE Hughes
Interaction of swainsonine with lymphoid and highly perfused tissues: a pharmacokinetics explanation for sustained immunomodulation.
Anticancer research 1997;17(6D):4345-6.
1994: William M Southerland
A molecular model of the folate binding site of Pneumocystis carinii dihydrofolate reductase.
Journal of computer-aided molecular design 1994;8(2):113-22.