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Simona Soverini

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Francesco Abate; Andrea Acquaviva; Massimo Delledonne; Alberto Ferrarini; Elisa Ficarra; Carmelo Foti; Ilaria Iacobucci; Giovanni Martinelli; Giulia Paciello; Simona Soverini; Enrico Macii
Bellerophontes: an RNA-Seq data analysis framework for chimeric transcripts discovery based on accurate fusion model.
Simona Soverini; Ilaria Iacobucci; Giovanni Martinelli; Gianantonio Rosti; Michele Baccarani
Advances in treatment of chronic myeloid leukemia with tyrosine kinase inhibitors: the evolving role of Bcr-Abl mutations and mutational analysis.
Ilaria Iacobucci; Nunzio Iraci; Annalisa Lonetti; Michele Baccarani; Sabina Chiaretti; Sandra Durante; Anna Ferrari; Robin Foà; Viviana Guadagnuolo; Monica Messina; Markus Müschen; Emanuela Ottaviani; Fabrizio Pane; Francesca Paoloni; Cristina Papayannidis; Giovanni Perini; Simona Soverini; Clelia Tiziana Storlazzi; Emanuele Valli; Marco Vignetti; Antonella Vitale; Giovanni Martinelli
IKAROS deletions dictate a unique gene expression signature in patients with adult B-cell acute lymphoblastic leukemia.

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All Publications

2012: Francesco Abate; Andrea Acquaviva; Massimo Delledonne; Alberto Ferrarini; Elisa Ficarra; Carmelo Foti; Ilaria Iacobucci; Giovanni Martinelli; Giulia Paciello; Simona Soverini; Enrico Macii
Bellerophontes: an RNA-Seq data analysis framework for chimeric transcripts discovery based on accurate fusion model.
Bioinformatics (Oxford, England) 2012;28(16):2114-21.
2012: Simona Soverini; Ilaria Iacobucci; Giovanni Martinelli; Gianantonio Rosti; Michele Baccarani
Advances in treatment of chronic myeloid leukemia with tyrosine kinase inhibitors: the evolving role of Bcr-Abl mutations and mutational analysis.
Pharmacogenomics 2012;13(11):1271-84.
2012: Ilaria Iacobucci; Nunzio Iraci; Annalisa Lonetti; Michele Baccarani; Sabina Chiaretti; Sandra Durante; Anna Ferrari; Robin Foà; Viviana Guadagnuolo; Monica Messina; Markus Müschen; Emanuela Ottaviani; Fabrizio Pane; Francesca Paoloni; Cristina Papayannidis; Giovanni Perini; Simona Soverini; Clelia Tiziana Storlazzi; Emanuele Valli; Marco Vignetti; Antonella Vitale; Giovanni Martinelli
IKAROS deletions dictate a unique gene expression signature in patients with adult B-cell acute lymphoblastic leukemia.
PloS one 2012;7(7):e40934.
2011: Robin Foà; Claudio Fozza; Anna Guarini; Ilaria Iacobucci; Pietro Leoni; Mario Luppi; Franco Mandelli; Giovanni Martinelli; Giovanna Meloni; Francesco Nobile; Francesca Paoloni; Simona Sica; Simona Soverini; Marco Vignetti; Antonella Vitale; Eliana Zuffa; Michele Baccarani; Anna Candoni; Carlo Castagnola; Giuseppe Cimino; Maria Stefania De Propris; Loredana Elia; Paola Fazi; Felicetto Ferrara
Dasatinib as first-line treatment for adult patients with Philadelphia chromosome-positive acute lymphoblastic leukemia.
Blood 2011;118(25):6521-8.
2011: Simona Soverini; Antonella Vitale; Angela Poerio; Alessandra Gnani; Sabrina Colarossi; Ilaria Iacobucci; Giuseppe Cimino; Loredana Elia; Annalisa Lonetti; Marco Vignetti; Stefania Paolini; Giovanna Meloni; Valeria di Maio; Cristina Papayannidis; Marilina Amabile; Anna Guarini; Michele Baccarani; Giovanni Martinelli; Robin Foà
Philadelphia-positive acute lymphoblastic leukemia patients already harbor BCR-ABL kinase domain mutations at low levels at the time of diagnosis.
Haematologica 2011;96(4):552-7.
2011: Simona Soverini; Gianantonio Rosti; Michele Baccarani; Ilaria Iacobucci; Giovanni Martinelli
Choosing the best second-line tyrosine kinase inhibitor in imatinib-resistant chronic myeloid leukemia patients harboring Bcr-Abl kinase domain mutations: how reliable is the IC₅₀?
The oncologist 2011;16(6):868-76.
2011: Simona Soverini; J Score; Ilaria Iacobucci; Angela Poerio; A Lonetti; A Gnani; S Colarossi; A Ferrari; F Castagnetti; Gianantonio Rosti; F Cervantes; A Hochhaus; M Delledonne; A Ferrarini; M Sazzini; Donata Luiselli; Michele Baccarani; N C P Cross; giovanni martinelli
IDH2 somatic mutations in chronic myeloid leukemia patients in blast crisis.
Leukemia 2011;25(1):178-81.
2010: Ilaria Iacobucci; Annalisa Lonetti; Francesca Paoloni; Cristina Papayannidis; Anna Ferrari; Clelia Tiziana Storlazzi; Marco Vignetti; Daniela Cilloni; Francesca Messa; Viviana Guadagnuolo; Stefania Paolini; Loredana Elia; Monica Messina; Antonella Vitale; Giovanna Meloni; Simona Soverini; Fabrizio Pane; Michele Baccarani; Robin Foà; Giovanni Martinelli
The PAX5 gene is frequently rearranged in BCR-ABL1-positive acute lymphoblastic leukemia but is not associated with outcome. A report on behalf of the GIMEMA Acute Leukemia Working Party.
Haematologica 2010;95(10):1683-90.
2010: Anna Baruzzi; Ilaria Iacobucci; Simona Soverini; Clifford A Lowell; Giovanni Martinelli; Giorgio Berton
c-Abl and Src-family kinases cross-talk in regulation of myeloid cell migration.
FEBS letters 2010;584(1):15-21.
2010: Ilaria Iacobucci; A Lonetti; F Messa; A Ferrari; Daniela Cilloni; Simona Soverini; F Paoloni; F Arruga; Emanuela Ottaviani; S Chiaretti; M Messina; Marco Vignetti; Cristina Papayannidis; A Vitale; Fabrizio Pane; Pier Paolo Piccaluga; S Paolini; G Berton; A Baruzzi; Giuseppe Saglio; Michele Baccarani; R Foà; giovanni martinelli
Different isoforms of the B-cell mutator activation-induced cytidine deaminase are aberrantly expressed in BCR-ABL1-positive acute lymphoblastic leukemia patients.
Leukemia 2010;24(1):66-73.
2009: Franck E Nicolini; Michael J Mauro; Giovanni Martinelli; Dong-Wook Kim; Simona Soverini; Martin C Müller; Andreas Hochhaus; Jorge Cortes; Charles Chuah; Inge H Dufva; Jane F Apperley; Fumiharu Yagasaki; Jay D Pearson; Senaka Peter; Cesar Sanz-Rodriguez; Claude Preudhomme; Francis Giles; John M Goldman; Wei Zhou
Epidemiologic study on survival of chronic myeloid leukemia and Ph(+) acute lymphoblastic leukemia patients with BCR-ABL T315I mutation.
Blood 2009;114(26):5271-8.
2009: Gianantonio Rosti; Francesca Palandri; Fausto Castagnetti; Massimo Breccia; Luciano Levato; Gabriele Gugliotta; Adele Capucci; Michele Cedrone; Carmen Fava; Tamara Intermesoli; Giovanna Rege Cambrin; Fabio Stagno; Mario Tiribelli; Marilina Amabile; Simona Luatti; Angela Poerio; Simona Soverini; Nicoletta Testoni; Giovanni Martinelli; Giuliana Alimena; Fabrizio Pane; Giuseppe Saglio; Michele Baccarani
Nilotinib for the frontline treatment of Ph(+) chronic myeloid leukemia.
Blood 2009;114(24):4933-8.
2009: Francesca Palandri; Fausto Castagnetti; Simona Soverini; Angela Poerio; Gabriele Gugliotta; Simona Luatti; Marilina Amabile; Giovanni Martinelli; Gianantonio Rosti; Michele Baccarani
Pancreatic enzyme elevation in chronic myeloid leukemia patients treated with nilotinib after imatinib failure.
Haematologica 2009;94(12):1758-61.
2009: Giovanni Martinelli; Ilaria Iacobucci; Clelia Tiziana Storlazzi; Marco Vignetti; Francesca Paoloni; Daniela Cilloni; Simona Soverini; Antonella Vitale; Sabina Chiaretti; Giuseppe Cimino; Cristina Papayannidis; Stefania Paolini; Loredana Elia; Paola Fazi; Giovanna Meloni; Sergio Amadori; Giuseppe Saglio; Fabrizio Pane; Michele Baccarani; Robin Foà
IKZF1 (Ikaros) deletions in BCR-ABL1-positive acute lymphoblastic leukemia are associated with short disease-free survival and high rate of cumulative incidence of relapse: a GIMEMA AL WP report.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(31):5202-7.
2009: Ilaria Iacobucci; Clelia Tiziana Storlazzi; Daniela Cilloni; Annalisa Lonetti; Emanuela Ottaviani; Simona Soverini; Annalisa Astolfi; Sabina Chiaretti; Antonella Vitale; Francesca Messa; Luciana Impera; Carmen Baldazzi; Pietro D'Addabbo; Cristina Papayannidis; Angelo Lonoce; Sabrina Colarossi; Marco Vignetti; Pier Paolo Piccaluga; Stefania Paolini; Domenico Russo; Fabrizio Pane; Giuseppe Saglio; Michele Baccarani; Robin Foà; Giovanni Martinelli
Identification and molecular characterization of recurrent genomic deletions on 7p12 in the IKZF1 gene in a large cohort of BCR-ABL1-positive acute lymphoblastic leukemia patients: on behalf of Gruppo Italiano Malattie Ematologiche dell'Adulto Acute Leukemia Working Party (GIMEMA AL WP).
Blood 2009;114(10):2159-67.
2009: Simona Soverini; Alessandra Gnani; Sabrina Colarossi; Fausto Castagnetti; Elisabetta Abruzzese; Stefania Paolini; Serena Merante; Ester Orlandi; Silvia de Matteis; Antonella Gozzini; Ilaria Iacobucci; Francesca Palandri; Gabriele Gugliotta; Cristina Papayannidis; Angela Poerio; Marilina Amabile; Daniela Cilloni; Gianantonio Rosti; Michele Baccarani; Giovanni Martinelli
Philadelphia-positive patients who already harbor imatinib-resistant Bcr-Abl kinase domain mutations have a higher likelihood of developing additional mutations associated with resistance to second- or third-line tyrosine kinase inhibitors.
Blood 2009;114(10):2168-71.
2009: Giovanni Martinelli; Ilaria Iacobucci; Cristina Papayannidis; Simona Soverini
New targets for Ph+ leukaemia therapy.
Best practice & research. Clinical haematology 2009;22(3):445-54.
2009: Michele Baccarani; Fausto Castagnetti; Gabriele Gugliotta; Francesca Palandri; Simona Soverini
Response definitions and European Leukemianet Management recommendations.
Best practice & research. Clinical haematology 2009;22(3):331-41.
2009: Timothy Hughes; Giuseppe Saglio; Susan Branford; Simona Soverini; Dong-Wook Kim; Martin C Müller; Giovanni Martinelli; Jorge Cortes; Lan Beppu; Enrico Gottardi; Dongho Kim; Philipp Erben; Yaping Shou; Ariful Haque; Neil Gallagher; Jerald Radich; Andreas Hochhaus
Impact of baseline BCR-ABL mutations on response to nilotinib in patients with chronic myeloid leukemia in chronic phase.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(25):4204-10.
2009: Leonardo Potenza; Francesco Volzone; Giovanni Riva; Simona Soverini; Silvia Martinelli; Ilaria Iacobucci; Alessandra Gnani; Patrizia Barozzi; Fabio Forghieri; Monica Morselli; Eleonora Zanetti; Monica Maccaferri; Michele Baccarani; Giovanni Martinelli; Giuseppe Torelli; Mario Luppi
Interferon-alpha may restore sensitivity to tyrosine-kinase inhibitors in Philadelphia chromosome positive acute lymphoblastic leukaemia with F317L mutation.
British journal of haematology 2009;146(2):227-30.
2009: Giovanni Martinelli; Ilaria Iacobucci; Simona Soverini; Pier Paolo Piccaluga; Daniela Cilloni; Fabrizio Pane
New mechanisms of resistance in Philadelphia chromosome acute lymphoblastic leukemia.
Expert review of hematology 2009;2(3):297-303.
2009: Massimo Breccia; Anna Maria Frustaci; Laura Cannella; Simona Soverini; Caterina Stefanizzi; Vincenzo Federico; Sara Grammatico; Michelina Santopietro; Giuliana Alimena
Sequential development of mutant clones in an imatinib resistant chronic myeloid leukaemia patient following sequential treatment with multiple tyrosine kinase inhibitors: an emerging problem?
Cancer chemotherapy and pharmacology 2009;64(1):195-7.
2009: Fausto Castagnetti; Francesca Palandri; Marilina Amabile; Nicoletta Testoni; Simona Luatti; Simona Soverini; Ilaria Iacobucci; Massimo Breccia; Giovanna Rege-Cambrin; Fabio Stagno; Giorgina Specchia; Piero Galieni; Franco Iuliano; Fabrizio Pane; Giuseppe Saglio; Giuliana Alimena; giovanni martinelli; Michele Baccarani; Gianantonio Rosti
Results of high-dose imatinib mesylate in intermediate Sokal risk chronic myeloid leukemia patients in early chronic phase: a phase 2 trial of the GIMEMA CML Working Party.
Blood 2009;113(15):3428-34.
2009: Elias Jabbour; Simona Soverini
Understanding the role of mutations in therapeutic decision making for chronic myeloid leukemia.
Seminars in hematology 2009;46(2 Suppl 3):S22-6.
2009: Francesca Palandri; Ilaria Iacobucci; Simona Soverini; Fausto Castagnetti; Angela Poerio; Nicoletta Testoni; Giuliana Alimena; Massimo Breccia; Giovanna Rege-Cambrin; Mario Tiribelli; Riccardo Varaldo; Elisabetta Abruzzese; Bruno Martino; Luigiana Luciano; Fabrizio Pane; Giuseppe Saglio; giovanni martinelli; Michele Baccarani; Gianantonio Rosti
Treatment of Philadelphia-positive chronic myeloid leukemia with imatinib: importance of a stable molecular response.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(3):1059-63.
2009: giovanni martinelli; Simona Soverini; Ilaria Iacobucci; Michele Baccarani
Intermittent targeting as a tool to minimize toxicity of tyrosine kinase inhibitor therapy.
Nature clinical practice. Oncology 2009;6(2):68-9.
2008: Ilaria Iacobucci; Annalisa Lonetti; Daniela Cilloni; Francesca Messa; Anna Ferrari; Roberta Zuntini; Simona Ferrari; Emanuela Ottaviani; Francesca Arruga; Stefania Paolini; Cristina Papayannidis; Pier Paolo Piccaluga; Simona Soverini; Giuseppe Saglio; Fabrizio Pane; Anna Baruzzi; Marco Vignetti; Giorgio Berton; Antonella Vitale; Sabina Chiaretti; Markus Müschen; Robin Foà; Michele Baccarani; giovanni martinelli
Identification of different Ikaros cDNA transcripts in Philadelphia-positive adult acute lymphoblastic leukemia by a high-throughput capillary electrophoresis sizing method.
Haematologica 2008;93(12):1814-21.
2008: Ilaria Iacobucci; Annalisa Lonetti; Francesca Messa; Daniela Cilloni; Francesca Arruga; Emanuela Ottaviani; Stefania Paolini; Cristina Papayannidis; Pier Paolo Piccaluga; Panagiota Giannoulia; Simona Soverini; Marilina Amabile; Angela Poerio; Giuseppe Saglio; Fabrizio Pane; Giorgio Berton; Anna Baruzzi; Antonella Vitale; Sabina Chiaretti; Giovanni Perini; Robin Foà; Michele Baccarani; giovanni martinelli
Expression of spliced oncogenic Ikaros isoforms in Philadelphia-positive acute lymphoblastic leukemia patients treated with tyrosine kinase inhibitors: implications for a new mechanism of resistance.
Blood 2008;112(9):3847-55.
2008: Stefano Monteghirfo; Francesca Isabella Tosetti; Claudia Ambrosini; Sara Stigliani; Sarah Pozzi; Francesco Frassoni; Gianfranco Fassina; Simona Soverini; Adriana Albini; Nicoletta Ferrari
Antileukemia effects of xanthohumol in Bcr/Abl-transformed cells involve nuclear factor-kappaB and p53 modulation.
Molecular cancer therapeutics 2008;7(9):2692-702.
2008: Simona Soverini; giovanni martinelli; Ilaria Iacobucci; Michele Baccarani
Imatinib mesylate for the treatment of chronic myeloid leukemia.
Expert review of anticancer therapy 2008;8(6):853-64.
2008: Francesca Palandri; Ilaria Iacobucci; giovanni martinelli; Marilina Amabile; Angela Poerio; Nicoletta Testoni; Simona Soverini; Fausto Castagnetti; Antonio de Vivo; Massimo Breccia; Giorgina Specchia; Elisabetta Abruzzese; Bruno Martino; Daniela Cilloni; Giuseppe Saglio; Fabrizio Pane; Anna Marina Liberati; Gianantonio Rosti; Michele Baccarani
Long-term outcome of complete cytogenetic responders after imatinib 400 mg in late chronic phase, philadelphia-positive chronic myeloid leukemia: the GIMEMA Working Party on CML.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(1):106-11.
2007: Michele Baccarani; Daniela Cilloni; Michela Rondoni; Emanuela Ottaviani; Francesca Messa; Serena Merante; Mario Tiribelli; Francesco Buccisano; Nicoletta Testoni; Enrico Gottardi; Antonio de Vivo; Emilia Giugliano; Ilaria Iacobucci; Stefania Paolini; Simona Soverini; Gianantonio Rosti; Francesca Rancati; Cinzia Astolfi; Fabrizio Pane; Giuseppe Saglio; giovanni martinelli
The efficacy of imatinib mesylate in patients with FIP1L1-PDGFRalpha-positive hypereosinophilic syndrome. Results of a multicenter prospective study.
Haematologica 2007;92(9):1173-9.
2007: Daniela Cilloni; Francesca Messa; giovanni martinelli; Enrico Gottardi; Francesca Arruga; Ilaria Defilippi; Sonia Carturan; Emanuela Messa; Milena Fava; Emilia Giugliano; Valentina Rosso; Renata Catalano; Serena Merante; P Nicoli; Michela Rondoni; Emanuela Ottaviani; Simona Soverini; Mario Tiribelli; Fabrizio Pane; Michele Baccarani; Giuseppe Saglio
WT1 transcript amount discriminates secondary or reactive eosinophilia from idiopathic hypereosinophilic syndrome or chronic eosinophilic leukemia.
Leukemia 2007;21(7):1442-50.
2007: Giovanni Martinelli; Ilaria Iacobucci; Simona Soverini; Francesca Palandri; Fausto Castagnetti; Gianantonio Rosti; Michele Baccarani
Nilotinib: a novel encouraging therapeutic option for chronic myeloid leukemia patients with imatinib resistance or intolerance.
Biologics : targets & therapy 2007;1(2):121-7.
2007: Simona Soverini; Ilaria Iacobucci; Michele Baccarani; giovanni martinelli
Targeted therapy and the T315I mutation in Philadelphia-positive leukemias.
Haematologica 2007;92(4):437-9.
2007: Ilaria Iacobucci; Livia Galletti; Marilina Amabile; Simona Soverini; Michele Baccarani; giovanni martinelli
Monitoring BCR-ABL transcript levels by real-time quantitative polymerase chain reaction: a linear regression equation to convert from BCR-ABL/B2M ratio to estimated BCR-ABL/ABL ratio.
Haematologica 2007;92(3):429-30.
2007: Simona Soverini; Sabrina Colarossi; Alessandra Gnani; Fausto Castagnetti; Gianantonio Rosti; Costanza Bosi; Stefania Paolini; Michela Rondoni; Pier Paolo Piccaluga; Francesca Palandri; Panagiota Giannoulia; Giulia Marzocchi; Simona Luatti; Nicoletta Testoni; Ilaria Iacobucci; Daniela Cilloni; Giuseppe Saglio; Michele Baccarani; giovanni martinelli
Resistance to dasatinib in Philadelphia-positive leukemia patients and the presence or the selection of mutations at residues 315 and 317 in the BCR-ABL kinase domain.
Haematologica 2007;92(3):401-4.
2007: Simona Soverini; giovanni martinelli; Sabrina Colarossi; Alessandra Gnani; Michela Rondoni; Fausto Castagnetti; Stefania Paolini; Gianantonio Rosti; Michele Baccarani
Second-line treatment with dasatinib in patients resistant to imatinib can select novel inhibitor-specific BCR-ABL mutants in Ph+ ALL.
The lancet oncology 2007;8(3):273-4.
2007: Rita Bussolari; olivia candini; D Colomer; Francesca Corradini; Clara Guerzoni; Samanta A Mariani; S Cattelani; C Silvestri; L Pecorari; Ilaria Iacobucci; Simona Soverini; Tommaso Fasano; giovanni martinelli; F Cervantes; Bruno Calabretta
Coding sequence and intron-exon junctions of the c-myb gene are intact in the chronic phase and blast crisis stages of chronic myeloid leukemia patients.
Leukemia research 2007;31(2):163-7.
2007: Gianantonio Rosti; Ilaria Iacobucci; Simona Bassi; Fausto Castagnetti; Marilina Amabile; Daniela Cilloni; Angela Poerio; Simona Soverini; Francesca Palandri; Giovanna Rege-Cambrin; Franco Iuliano; Giuliana Alimena; Roberto Latagliata; Nicoletta Testoni; Fabrizio Pane; Giuseppe Saglio; Michele Baccarani; giovanni martinelli
Impact of age on the outcome of patients with chronic myeloid leukemia in late chronic phase: results of a phase II study of the GIMEMA CML Working Party.
Haematologica 2007;92(1):101-5.
2006: Simona Soverini; Sabrina Colarossi; Alessandra Gnani; Gianantonio Rosti; Fausto Castagnetti; Angela Poerio; Ilaria Iacobucci; Marilina Amabile; Elisabetta Abruzzese; Ester Orlandi; Franca Radaelli; Fabrizio Ciccone; Mario Tiribelli; Roberto di Lorenzo; Clementina Caracciolo; Barbara Izzo; Fabrizio Pane; Giuseppe Saglio; Michele Baccarani; giovanni martinelli
Contribution of ABL kinase domain mutations to imatinib resistance in different subsets of Philadelphia-positive patients: by the GIMEMA Working Party on Chronic Myeloid Leukemia.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(24):7374-9.
2006: giovanni martinelli; Ilaria Iacobucci; Simona Soverini; Daniela Cilloni; Giuseppe Saglio; Fabrizio Pane; Michele Baccarani
Monitoring minimal residual disease and controlling drug resistance in chronic myeloid leukaemia patients in treatment with imatinib as a guide to clinical management.
Hematological oncology 2006;24(4):196-204.
2006: Simona Soverini; giovanni martinelli; Sabrina Colarossi; Alessandra Gnani; Fausto Castagnetti; Gianantonio Rosti; Costanza Bosi; Stefania Paolini; Michela Rondoni; Pier Paolo Piccaluga; Francesca Palandri; Panagiota Giannoulia; Giulia Marzocchi; Simona Luatti; Nicoletta Testoni; Ilaria Iacobucci; Daniela Cilloni; Giuseppe Saglio; Michele Baccarani
Presence or the emergence of a F317L BCR-ABL mutation may be associated with resistance to dasatinib in Philadelphia chromosome-positive leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(33):e51-2.
2006: Timothy Hughes; Michael W N Deininger; Andreas Hochhaus; Susan Branford; Jerald P Radich; Jaspal Kaeda; Michele Baccarani; Jorge Cortes; Nicholas C P Cross; Brian J Druker; Jean Gabert; David Grimwade; Rüdiger Hehlmann; Suzanne Kamel-Reid; Jeffrey H Lipton; Janina Longtine; giovanni martinelli; Giuseppe Saglio; Simona Soverini; Wendy Stock; John M Goldman
Monitoring CML patients responding to treatment with tyrosine kinase inhibitors: review and recommendations for harmonizing current methodology for detecting BCR-ABL transcripts and kinase domain mutations and for expressing results.
Blood 2006;108(1):28-37.
2006: Ilaria Iacobucci; Giuseppe Saglio; Gianantonio Rosti; Nicoletta Testoni; Fabrizio Pane; Marilina Amabile; Angela Poerio; Simona Soverini; Simona Bassi; Daniela Cilloni; Renato Bassan; Massimo Breccia; Francesco Lauria; Barbara Izzo; Serena Merante; Francesco Frassoni; Stefania Paolini; Enrico Montefusco; Michele Baccarani; giovanni martinelli
Achieving a major molecular response at the time of a complete cytogenetic response (CCgR) predicts a better duration of CCgR in imatinib-treated chronic myeloid leukemia patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(10):3037-42.
2006: giovanni martinelli; Ilaria Iacobucci; Gianantonio Rosti; Fabrizio Pane; Marilina Amabile; Fausto Castagnetti; Daniela Cilloni; Simona Soverini; Nicoletta Testoni; Giorgina Specchia; Serena Merante; Alfonso Zaccaria; F Frassoni; Giuseppe Saglio; Michele Baccarani
Prediction of response to imatinib by prospective quantitation of BCR-ABL transcript in late chronic phase chronic myeloid leukemia patients.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2006;17(3):495-502.
2006: Serena Merante; Merante Serena; Guido Chichino; Chichino Guido; Emanuela Boveri; Boveri Emanuela; Enrico Gottardi; Gottardi Enrico; Simona Soverini; Soverini Simona; Daniela Cilloni; Cilloni Daniela; giovanni martinelli; Martinelli Giovanni
First case of an AIDS patient with systemic mast cell disease associated with FIP1-positive eosinophilia treated with imatinib mesylate therapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(4):e6-7.
2006: Ilaria Iacobucci; Gianantonio Rosti; Marilina Amabile; Angela Poerio; Simona Soverini; Daniela Cilloni; Nicoletta Testoni; Elisabetta Abruzzese; Enrico Montefusco; Emanuela Ottaviani; Franco Iuliano; Domenico Russo; marco gobbi; Giuliana Alimena; Bruno Martino; Carolina Terragna; Fabrizio Pane; Giuseppe Saglio; Michele Baccarani; giovanni martinelli
Comparison between patients with Philadelphia-positive chronic phase chronic myeloid leukemia who obtained a complete cytogenetic response within 1 year of imatinib therapy and those who achieved such a response after 12 months of treatment.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(3):454-9.
2005: giovanni martinelli; Simona Soverini; Gianantonio Rosti; Michele Baccarani
Dual tyrosine kinase inhibitors in chronic myeloid leukemia.
Leukemia 2005;19(11):1872-9.
2005: Simona Soverini; giovanni martinelli; Gianantonio Rosti; Simona Bassi; Marilina Amabile; Angela Poerio; Barbara Giannini; Elena Trabacchi; Fausto Castagnetti; Nicoletta Testoni; Simona Luatti; Antonio de Vivo; Daniela Cilloni; Barbara Izzo; Milena Fava; Elisabetta Abruzzese; Daniele Alberti; Fabrizio Pane; Giuseppe Saglio; Michele Baccarani
ABL mutations in late chronic phase chronic myeloid leukemia patients with up-front cytogenetic resistance to imatinib are associated with a greater likelihood of progression to blast crisis and shorter survival: a study by the GIMEMA Working Party on Chronic Myeloid Leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(18):4100-9.
2005: giovanni martinelli; Simona Soverini; Gianantonio Rosti; Daniela Cilloni; Michele Baccarani
New tyrosine kinase inhibitors in chronic myeloid leukemia.
Haematologica 2005;90(4):534-41.
2004: Michele Baccarani; giovanni martinelli; Gianantonio Rosti; Elena Trabacchi; Nicoletta Testoni; Simona Bassi; Marilina Amabile; Simona Soverini; Fausto Castagnetti; Daniela Cilloni; Barbara Izzo; Antonio de Vivo; Emanuela Messa; Francesca Bonifazi; Angela Poerio; Simona Luatti; Emilia Giugliano; Daniele Alberti; Gianluca Fincato; Domenico Russo; Fabrizio Pane; Giuseppe Saglio
Imatinib and pegylated human recombinant interferon-alpha2b in early chronic-phase chronic myeloid leukemia.
Blood 2004;104(13):4245-51.
2004: Pier Luigi Zinzani; Alessandro Pulsoni; Alessio Perrotti; Simona Soverini; Francesco Zaja; Amalia De Renzo; Sergio Storti; Vito Michele Lauta; Luciano Guardigni; Paolo Gentilini; Alessandra Tucci; Anna Lia Molinari; marco gobbi; Brunangelo Falini; Patrizia Fattori; Fabrizio Ciccone; Lapo Alinari; Maurizio Martelli; Stefano Pileri; Sante Tura; Michele Baccarani
Fludarabine plus mitoxantrone with and without rituximab versus CHOP with and without rituximab as front-line treatment for patients with follicular lymphoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(13):2654-61.
2004: Simona Soverini; giovanni martinelli; Marilina Amabile; Angela Poerio; Michele Bianchini; Gianantonio Rosti; Fabrizio Pane; Giuseppe Saglio; Michele Baccarani
Denaturing-HPLC-based assay for detection of ABL mutations in chronic myeloid leukemia patients resistant to Imatinib.
Clinical chemistry 2004;50(7):1205-13.
2004: Pier Paolo Piccaluga; Michele Malagola; Michela Rondoni; Marilina Amabile; Stefania Paolini; Simona Soverini; Stavroula Gaitani; Giuseppe Visani; Michele Baccarani; giovanni martinelli
Dose increase of imatinib mesylate may overcome acquired resistance in bcr/abl-positive acute lymphoid leukaemia.
European journal of haematology 2004;72(4):302-3.
2004: Gianantonio Rosti; giovanni martinelli; Simona Bassi; Marilina Amabile; Elena Trabacchi; Barbara Giannini; Daniela Cilloni; Barbara Izzo; Antonio de Vivo; Nicoletta Testoni; Giovanna Rege Cambrin; Francesca Bonifazi; Simona Soverini; Simona Luatti; Enrico Gottardi; Daniele Alberti; Fabrizio Pane; Francesco Salvatore; Giuseppe Saglio; Michele Baccarani
Molecular response to imatinib in late chronic-phase chronic myeloid leukemia.
Blood 2004;103(6):2284-90.
2003: Michele Bianchini; Emanuela Ottaviani; Tiziana Grafone; Barbara Giannini; Simona Soverini; Carolina Terragna; Marilina Amabile; Pier Paolo Piccaluga; Michele Malagola; Michela Rondoni; Costanza Bosi; Michele Baccarani; giovanni martinelli
Rapid detection of Flt3 mutations in acute myeloid leukemia patients by denaturing HPLC.
Clinical chemistry 2003;49(10):1642-50.
2003: Simona Soverini; Michele Cavo; Claudia Cellini; Carolina Terragna; Elena Zamagni; Deborah Ruggeri; Nicoletta Testoni; Patrizia Tosi; Antonio de Vivo; Marilina Amabile; Tiziana Grafone; Emanuela Ottaviani; Barbara Giannini; Delia Cangini; Francesca Bonifazi; Antonino Neri; Sonia Fabris; Sante Tura; Michele Baccarani; giovanni martinelli
Cyclin D1 overexpression is a favorable prognostic variable for newly diagnosed multiple myeloma patients treated with high-dose chemotherapy and single or double autologous transplantation.
Blood 2003;102(5):1588-94.
2003: giovanni martinelli; Silvia Buonamici; Giuseppe Visani; Michele Malagola; Pier Paolo Piccaluga; Alessandro Isidori; Costanza Bosi; Francesca Bonifazi; Simona Soverini; Carolina Terragna; Marilina Amabile; Barbara Giannini; Michele Baccarani
Molecular monitoring of acute myeloid leukemia associated with inv(16): threshold of CBFbeta/MYH11 transcript copy number above which relapse occurs and below which continuous Complete Remission is likely.
Leukemia 2003;17(3):650-1; author reply 651-2.
2002: Simona Soverini; Carolina Terragna; Nicoletta Testoni; Deborah Ruggeri; Patrizia Tosi; Elena Zamagni; Claudia Cellini; Michele Cavo; Michele Baccarani; Sante Tura; giovanni martinelli
Novel mutation and RNA splice variant of fibroblast growth factor receptor 3 in multiple myeloma patients at diagnosis.
Haematologica 2002;87(10):1036-40.
2002: giovanni martinelli; Marilina Amabile; Barbara Giannini; Carolina Terragna; Emanuela Ottaviani; Simona Soverini; Giuseppe Saglio; Gianantonio Rosti; Michele Baccarani
Novel types of bcr-abl transcript with breakpoints in BCR exon 8 found in Philadelphia positive patients with typical chronic myeloid leukemia retain the sequence encoding for the DBL- and CDC24 homology domains but not the pleckstrin homology one.
Haematologica 2002;87(7):688-94; discussion 694.
2001: giovanni martinelli; Patrizia Tosi; Emanuela Ottaviani; Simona Soverini; Sante Tura
Molecular therapy for multiple myeloma.
Haematologica 2001;86(9):908-17.
2001: Marilina Amabile; Barbara Giannini; Nicoletta Testoni; Vittorio Montefusco; Gianantonio Rosti; C Zardini; Carolina Terragna; Silvia Buonamici; Emanuela Ottaviani; Simona Soverini; Mauro Fiacchini; Simona Bassi; Antonio de Vivo; Elena Trabacchi; Giuseppe Saglio; Fabrizio Pane; Michele Baccarani; Sante Tura; giovanni martinelli
Real-time quantification of different types of bcr-abl transcript in chronic myeloid leukemia.
Haematologica 2001;86(3):252-9.
2000: giovanni martinelli; Carolina Terragna; Elena Zamagni; Sonia Ronconi; Patrizia Tosi; Roberto M Lemoli; Giuseppe Bandini; Nicoletta Testoni; Marilina Amabile; Emanuela Ottaviani; Silvia Buonamici; Simona Soverini; Vittorio Montefusco; Antonio de Vivo; Francesca Bonifazi; Sante Tura; Michele Cavo
Polymerase chain reaction-based detection of minimal residual disease in multiple myeloma patients receiving allogeneic stem cell transplantation.
Haematologica 2000;85(9):930-4.