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Mark Sowden

Research Profile

Physiology

RNA Editing

Chemicals & Drugs

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Concepts & Ideas

Molecular Sequence Data

Anatomy

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Amino Acid Sequences

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Sequence Alignment

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Publications

TOP 3
David M Lehmann; Chad A Galloway; Celeste MacElrevey; Mark P Sowden; Joseph E Wedekind; Harold C Smith
Functional characterization of APOBEC-1 complementation factor phosphorylation sites.
Ryan P Bennett; Elie Diner; Mark P Sowden; Joshua A Lees; Joseph E Wedekind; Harold C Smith
APOBEC-1 and AID are nucleo-cytoplasmic trafficking proteins but APOBEC3G cannot traffic.
H Travis Ichikawa; Mark P Sowden; Andrew T Torelli; Jürgen Bachl; Pinwei Huang; Geoff Dance; Shauna Marr; Jacques Robert; Joseph E Wedekind; Harold C Smith; Andrea Bottaro
Structural phylogenetic analysis of activation-induced deaminase function.

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All Publications

2007: David M Lehmann; Chad A Galloway; Celeste MacElrevey; Mark P Sowden; Joseph E Wedekind; Harold C Smith
Functional characterization of APOBEC-1 complementation factor phosphorylation sites.
Biochimica et biophysica acta 2007;1773(3):408-18.
2006: Ryan P Bennett; Elie Diner; Mark P Sowden; Joshua A Lees; Joseph E Wedekind; Harold C Smith
APOBEC-1 and AID are nucleo-cytoplasmic trafficking proteins but APOBEC3G cannot traffic.
Biochemical and biophysical research communications 2006;350(1):214-9.
2006: H Travis Ichikawa; Mark P Sowden; Andrew T Torelli; Jürgen Bachl; Pinwei Huang; Geoff Dance; Shauna Marr; Jacques Robert; Joseph E Wedekind; Harold C Smith; Andrea Bottaro
Structural phylogenetic analysis of activation-induced deaminase function.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(1):355-61.
2006: Janet D Sparks; Heidi L Collins; Doru V Chirieac; Joanne Cianci; Jenny Jokinen; Mark P Sowden; Chad A Galloway; Charles E Sparks
Hepatic very-low-density lipoprotein and apolipoprotein B production are increased following in vivo induction of betaine-homocysteine S-methyltransferase.
The Biochemical journal 2006;395(2):363-71.
2006: David M Lehmann; Chad A Galloway; Mark P Sowden; Harold C Smith
Metabolic regulation of apoB mRNA editing is associated with phosphorylation of APOBEC-1 complementation factor.
Nucleic acids research 2006;34(11):3299-308.
2004: Harold C Smith; Andrea Bottaro; Mark P Sowden; Joseph E Wedekind
Activation induced deaminase: the importance of being specific.
Trends in genetics : TIG 2004;20(6):224-7.
2004: Kefang Xie; Mark P Sowden; Geoff Dance; Andrew T Torelli; Harold C Smith; Joseph E Wedekind
The structure of a yeast RNA-editing deaminase provides insight into the fold and function of activation-induced deaminase and APOBEC-1.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(21):8114-9.
2004: Mark P Sowden; David M Lehmann; Xiaoyan Lin; Charles O Smith; Harold C Smith
Identification of novel alternative splice variants of APOBEC-1 complementation factor with different capacities to support apolipoprotein B mRNA editing.
The Journal of biological chemistry 2004;279(1):197-206.
2003: Joseph E Wedekind; Geoff Dance; Mark P Sowden; Harold C Smith
Messenger RNA editing in mammals: new members of the APOBEC family seeking roles in the family business.
Trends in genetics : TIG 2003;19(4):207-16.
2003: Chad A Galloway; Mark P Sowden; Harold C Smith
Increasing the yield of soluble recombinant protein expressed in E. coli by induction during late log phase.
BioTechniques 2003;34(3):524-6, 528, 530.
2002: Geoff Dance; Mark P Sowden; Luca Cartegni; Ellen Cooper; Adrian R Krainer; Harold C Smith
Two proteins essential for apolipoprotein B mRNA editing are expressed from a single gene through alternative splicing.
The Journal of biological chemistry 2002;277(15):12703-9.
2002: Mark P Sowden; Nazzareno Ballatori; Karen L de Mesy Jensen; Lakesha Hamilton Reed; Harold C Smith
The editosome for cytidine to uridine mRNA editing has a native complexity of 27S: identification of intracellular domains containing active and inactive editing factors.
Journal of cell science 2002;115(Pt 5):1027-39.
2001: A Giangreco; Mark P Sowden; I Mikityansky; Harold C Smith
Ethanol stimulates apolipoprotein B mRNA editing in the absence of de novo RNA or protein synthesis.
Biochemical and biophysical research communications 2001;289(5):1162-7.
2001: Mark P Sowden; Harold C Smith
Commitment of apolipoprotein B RNA to the splicing pathway regulates cytidine-to-uridine editing-site utilization.
The Biochemical journal 2001;359(Pt 3):697-705.
2001: Y Yang; Mark P Sowden; Y Yang; Harold C Smith
Intracellular trafficking determinants in APOBEC-1, the catalytic subunit for cytidine to uridine editing of apolipoprotein B mRNA.
Experimental cell research 2001;267(2):153-64.
2000: Y Yang; Mark P Sowden; Harold C Smith
Induction of cytidine to uridine editing on cytoplasmic apolipoprotein B mRNA by overexpressing APOBEC-1.
The Journal of biological chemistry 2000;275(30):22663-9.
2000: Geoff Dance; Mark P Sowden; Y Yang; Harold C Smith
APOBEC-1 dependent cytidine to uridine editing of apolipoprotein B RNA in yeast.
Nucleic acids research 2000;28(2):424-9.
1999: J F Siddiqui; D Van Mater; Mark P Sowden; Harold C Smith
Disproportionate relationship between APOBEC-1 expression and apolipoprotein B mRNA editing activity.
Experimental cell research 1999;252(1):154-64.
1999: Mark P Sowden; Heidi L Collins; Harold C Smith; Timothy A Garrow; Janet D Sparks; Charles E Sparks
Apolipoprotein B mRNA and lipoprotein secretion are increased in McArdle RH-7777 cells by expression of betaine-homocysteine S-methyltransferase.
The Biochemical journal 1999;341 ( Pt 3)():639-45.
1998: D Van Mater; Mark P Sowden; Joanne Cianci; Janet D Sparks; Charles E Sparks; Nazzareno Ballatori; Harold C Smith
Ethanol increases apolipoprotein B mRNA editing in rat primary hepatocytes and McArdle cells.
Biochemical and biophysical research communications 1998;252(2):334-9.
1998: Janet D Sparks; Thuy L Phung; M Bolognino; Joanne Cianci; R Khurana; R G Peterson; Mark P Sowden; James P Corsetti; Charles E Sparks
Lipoprotein alterations in 10- and 20-week-old Zucker diabetic fatty rats: hyperinsulinemic versus insulinopenic hyperglycemia.
Metabolism: clinical and experimental 1998;47(11):1315-24.
1998: Mark P Sowden; Matthew J Eagleton; Harold C Smith
Apolipoprotein B RNA sequence 3' of the mooring sequence and cellular sources of auxiliary factors determine the location and extent of promiscuous editing.
Nucleic acids research 1998;26(7):1644-52.
1998: J Stewart; P Kozlowski; Mark P Sowden; E Messing; Harold C Smith
A quantitative assay for assessing allelic proportions by iterative gap ligation.
Nucleic acids research 1998;26(4):961-6.
1997: Janet D Sparks; Heidi L Collins; I Sabio; Mark P Sowden; Harold C Smith; Joanne Cianci; Charles E Sparks
Effects of fatty acids on apolipoprotein B secretion by McArdle RH-7777 rat hepatoma cells.
Biochimica et biophysica acta 1997;1347(1):51-61.
1996: Harold C Smith; Mark P Sowden
Base-modification mRNA editing through deamination--the good, the bad and the unregulated.
Trends in genetics : TIG 1996;12(10):418-24.
1996: Thuy L Phung; Mark P Sowden; Janet D Sparks; Charles E Sparks; Harold C Smith
Regulation of hepatic apolipoprotein B RNA editing in the genetically obese Zucker rat.
Metabolism: clinical and experimental 1996;45(9):1056-8.
1996: Mark P Sowden; J K Hamm; Sherry L Spinelli; Harold C Smith
Determinants involved in regulating the proportion of edited apolipoprotein B RNAs.
RNA (New York, N.Y.) 1996;2(3):274-88.
1996: Mark P Sowden; J K Hamm; Harold C Smith
Overexpression of APOBEC-1 results in mooring sequence-dependent promiscuous RNA editing.
The Journal of biological chemistry 1996;271(6):3011-7.
1996: Gary R Skuse; Amedeo Cappione; Mark P Sowden; Linda Metheny-Barlow; Harold C Smith
The neurofibromatosis type I messenger RNA undergoes base-modification RNA editing.
Nucleic acids research 1996;24(3):478-85.