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Akintunde Sowunmi

Research Profile

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Nigeria

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TOP 3
Akintunde Sowunmi; Elsie O Adewoye; Grace O Gbotosho; Christian T Happi; Obaro S Michael; Titilope M Okuboyejo; Abayomi O Sijuade; Onikepe Folarin
Therapeutic efficacy of artesunate-amodiaquine combinations and the plasma and saliva concentrations of desethylamodiaquine in children with acute uncomplicated Plasmodium falciparum malaria.
Carolina Bustamante; Onikepe A Folarin; Grace O Gbotosho; Elieth A Mesquita; Ayoade Oduola; Akintunde Sowunmi; Claudio José Struchiner; Amilcar Tanuri; Dyann F Wirth; Mariano G Zalis; Camila N Batista; Rodrigo M Brindeiro; Christian T Happi
In vitro-reduced susceptibility to artemether in P. falciparum and its association with polymorphisms on transporter genes.
Akintunde Sowunmi; Titilope M Okuboyejo; Ibukun A Akinrinola; Grace O Gbotosho; Christian T Happi
A simple dose regimen of artesunate and amodiaquine based on arm span- or age range for childhood falciparum malaria: a preliminary evaluation.

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All Publications

2013: Akintunde Sowunmi; Elsie O Adewoye; Grace O Gbotosho; Christian T Happi; Obaro S Michael; Titilope M Okuboyejo; Abayomi O Sijuade; Onikepe Folarin
Therapeutic efficacy of artesunate-amodiaquine combinations and the plasma and saliva concentrations of desethylamodiaquine in children with acute uncomplicated Plasmodium falciparum malaria.
American journal of therapeutics 2013;20(1):48-56.
2012: Carolina Bustamante; Onikepe A Folarin; Grace O Gbotosho; Elieth A Mesquita; Ayoade Oduola; Akintunde Sowunmi; Claudio José Struchiner; Amilcar Tanuri; Dyann F Wirth; Mariano G Zalis; Camila N Batista; Rodrigo M Brindeiro; Christian T Happi
In vitro-reduced susceptibility to artemether in P. falciparum and its association with polymorphisms on transporter genes.
The Journal of infectious diseases 2012;206(3):324-32.
2012: Akintunde Sowunmi; Titilope M Okuboyejo; Ibukun A Akinrinola; Grace O Gbotosho; Christian T Happi
A simple dose regimen of artesunate and amodiaquine based on arm span- or age range for childhood falciparum malaria: a preliminary evaluation.
Journal of tropical pediatrics 2012;58(4):263-8.
2012: Grace O Gbotosho; Christian T Happi; Titilope M Okuboyejo; Akintunde Sowunmi; Onikepe O Folarin; Elsie O Adewoye
A simple dose regimen of artesunate and amodiaquine based on age or body weight range for uncomplicated falciparum malaria in children: comparison of therapeutic efficacy with standard dose regimen of artesunate and amodiaquine and artemether-lumefantrine.
American journal of therapeutics 2012;19(4):e122-31.
2012: Grace O Gbotosho; Titilope M Okuboyejo; Akintunde Sowunmi; Christian T Happi
Oral artesunate-amodiaquine and artemether-lumefantrine in the treatment of uncomplicated hyperparasitaemic Plasmodium falciparum malaria in children.
Journal of tropical pediatrics 2012;58(2):151-3.
2012: Grace O Gbotosho; Carolina Bustamante; Onikepe Folarin; Elieth Mesquita; Ayoade M J Oduola; Akintunde Sowunmi; Mariano G Zalis; Luis Hildebrando Pereira da Silva; Christian T Happi
Different patterns of pfcrt and pfmdr1 polymorphisms in P. falciparum isolates from Nigeria and Brazil: the potential role of antimalarial drug selection pressure.
The American journal of tropical medicine and hygiene 2012;86(2):211-3.
2012: Grace O Gbotosho; Christian T Happi; Omowunmi Lawal; Abayomi Sijuade; Akintunde Sowunmi; Ayoade Oduola
A high performance liquid chromatographic assay of mefloquine in saliva after a single oral dose in healthy adult Africans.
Malaria journal 2012;11():59.
2011: Onikepe Folarin; Grace O Gbotosho; A M J Oduola; Akintunde Sowunmi; M G Zalis; C Bustamante; Christian T Happi
In vitro amodiaquine resistance and its association with mutations in pfcrt and pfmdr1 genes of Plasmodium falciparum isolates from Nigeria.
Acta tropica 2011;120(3):224-30.
2011: Grace O Gbotosho; Christian T Happi; Akintunde Sowunmi; Titilope Modupe Okuboyejo
Plasmodium falciparum gametocyte carriage, sex ratios and asexual parasite rates in Nigerian children before and after a treatment protocol policy change instituting the use of artemisinin-based combination therapies.
Memórias do Instituto Oswaldo Cruz 2011;106(6):685-90.
2011: Grace O Gbotosho; Christian T Happi; Obaro Stanley Michael; Titilope Modupe Okuboyejo; Akintunde Sowunmi; Onikepe Folarin; Elsie Olufunke Adewoye
Plasmodium falciparum gametocyte carriage, emergence, clearance and population sex ratios in anaemic and non-anaemic malarious children.
Memórias do Instituto Oswaldo Cruz 2011;106(5):562-9.
2011: Grace O Gbotosho; Akintunde Sowunmi; Christian T Happi; Titilope M Okuboyejo
Therapeutic efficacies of artemisinin-based combination therapies in Nigerian children with uncomplicated falciparum malaria during five years of adoption as first-line treatments.
The American journal of tropical medicine and hygiene 2011;84(6):936-43.
2011: Grace O Gbotosho; Akintunde Sowunmi; Titilope M Okuboyejo; Christian T Happi; Onikepe Folarin; Obaro S Michael; Elsie O Adewoye
Therapeutic efficacy and effects of artemether-lumefantrine and artesunate-amodiaquine coformulated or copackaged on malaria-associated anemia in children with uncomplicated Plasmodium falciparum malaria in Southwest Nigeria.
The American journal of tropical medicine and hygiene 2011;84(5):813-9.
2011: Akintunde Sowunmi; Grace O Gbotosho; Christian T Happi; Onikepe Folarin; Titilope Okuboyejo; Obaro Michael; Bayo Fatunmbi
Use of area under the curve to evaluate the effects of antimalarial drugs on malaria-associated anemia after treatment.
American journal of therapeutics 2011;18(3):190-7.
2011: Akintunde Sowunmi; Titilope M Okuboyejo; Grace O Gbotosho; Christian T Happi
Risk factors for gametocyte carriage in uncomplicated falciparum malaria in children before and after artemisinin-based combination treatments.
Chemotherapy 2011;57(6):497-504.
2011: Akintunde Sowunmi; Titilope M Okuboyejo; Grace O Gbotosho; Christian T Happi
Risk factors for Plasmodium falciparum hyperparasitaemia in malarious children.
BMC infectious diseases 2011;11():268.
2011: Oyindamola Abiodun; Grace Gbotosho; Edith Ajaiyeoba; Tientcha Happi; Folusho Oludare Falade; Sergio Wittlin; Akintunde Sowunmi; Reto Brun; Ayoade Oduola
In vitro antiplasmodial activity and toxicity assessment of some plants from Nigerian ethnomedicine.
Pharmaceutical biology 2011;49(1):9-14.
2010: Grace O Gbotosho; Christian T Happi; Onikepe Folarin; Ochuko Keyamo; Akintunde Sowunmi; Ayoade M J Oduola
Rapid detection of lactate dehydrogenase and genotyping of Plasmodium falciparum in saliva of children with acute uncomplicated malaria.
The American journal of tropical medicine and hygiene 2010;83(3):496-501.
2010: Akintunde Sowunmi; Grace O Gbotosho; Christian T Happi; Babasola A Fateye
Factors contributing to anaemia after uncomplicated Plasmodiumfalciparum malaria in children.
Acta tropica 2010;113(2):155-61.
2010: Idowu Adejumoke Ayede; Adegoke G Falade; Akintunde Sowunmi; Frans Herwig Jansen
An open randomized clinical trial in comparing two artesunate-based combination treatments on Plasmodium falciparum malaria in Nigerian children: artesunate/sulphamethoxypyrazine/pyrimethamine (fixed dose over 24 hours) versus artesunate/amodiaquine (fixed dose over 48 hours).
Malaria journal 2010;9():378.
2010: Obaro S Michael; Grace O Gbotosho; Onikepe Folarin; Titilope Okuboyejo; Akintunde Sowunmi; Ayoade M J Oduola; Christian T Happi
Early variations in plasmodium falciparum dynamics in Nigerian children after treatment with two artemisinin-based combinations: implications on delayed parasite clearance.
Malaria journal 2010;9():335.
2010: Akintunde Sowunmi; olufunke adewoye; Grace O Gbotsho; Christian T Happi; Abayomi Sijuade; Onikepe Folarin; Titilope M Okuboyejo; Obaro S Michael
Factors contributing to delay in parasite clearance in uncomplicated falciparum malaria in children.
Malaria journal 2010;9():53.
2009: Akintunde Sowunmi; Grace O Gbotosho; Christian Happi; Titilope Okuboyejo; Onikepe Folarin; Sulayman Balogun; Obaro Michael
Therapeutic efficacy and effects of artesunate-mefloquine and mefloquine alone on malaria-associated anemia in children with uncomplicated Plasmodium falciparum malaria in southwest Nigeria.
The American journal of tropical medicine and hygiene 2009;81(6):979-86.
2009: Akintunde Sowunmi; Grace O Gbotosho; Christian T Happi; Onikepe Folarin; Sulayman T Balogun
Population structure of Plasmodium falciparum gametocyte sex ratios in malarious children in an endemic area.
Parasitology international 2009;58(4):438-43.
2009: Christian T Happi; Grace O Gbotosho; Onikepe Folarin; Akintunde Sowunmi; T Hudson; M O'Neil; Wilbur K Milhous; Dyann F Wirth; A M J Oduola
Selection of Plasmodium falciparum multidrug resistance gene 1 alleles in asexual stages and gametocytes by artemether-lumefantrine in Nigerian children with uncomplicated falciparum malaria.
Antimicrobial agents and chemotherapy 2009;53(3):888-95.
2009: Akintunde Sowunmi; Sulayman T Balogun; Grace O Gbotosho; Christian T Happi
Plasmodium falciparum gametocyte sex ratios in symptomatic children treated with antimalarial drugs.
Acta tropica 2009;109(2):108-17.
2009: Grace O Gbotosho; Christian T Happi; Abideen Ganiyu; O A T Ogundahunsi; Akintunde Sowunmi; Ayoade M Oduola
Potential contribution of prescription practices to the emergence and spread of chloroquine resistance in south-west Nigeria: caution in the use of artemisinin combination therapy.
Malaria journal 2009;8():313.
2009: Akintunde Sowunmi; Oluchi O Nkogho; Titilope M Okuboyejo; Grace O Gbotosho; Christian T Happi; olufunke adewoye
Effects of mefloquine and artesunate mefloquine on the emergence, clearance and sex ratio of Plasmodium falciparum gametocytes in malarious children.
Malaria journal 2009;8():297.
2009: Grace O Gbotosho; Christian T Happi; Abayomi O Sijuade; Akintunde Sowunmi; Ayoade M J Oduola
A simple cost-effective high performance liquid chromatographic assay of sulphadoxine in whole blood spotted on filter paper for field studies.
Malaria journal 2009;8():238.
2009: Zul Premji; Rich E Umeh; Seth Owusu-Agyei; Fabian Esamai; Emmanuel U Ezedinachi; Stephen Oguche; Steffen Borrmann; Akintunde Sowunmi; Stephan Duparc; Paula L Kirby; Allan Pamba; Lynda Kellam; Robert Guiguemdé; Brian Greenwood; Stephen A Ward; Peter A Winstanley
Chlorproguanil-dapsone-artesunate versus artemether-lumefantrine: a randomized, double-blind phase III trial in African children and adolescents with uncomplicated Plasmodium falciparum malaria.
PloS one 2009;4(8):e6682.
2009: Akintunde Sowunmi; Sulayman T Balogun; Grace O Gbotosho; Christian T Happi
Effects of amodiaquine, artesunate, and artesunate-amodiaquine on Plasmodium falciparum malaria-associated anaemia in children.
Acta tropica 2009;109(1):55-60.
2008: Akintunde Sowunmi; Sulayman T Balogun; Grace O Gbotosho; Christian T Happi
Some features of primary and recrudescent amodiaquine-resistant Plasmodium falciparum infections in Nigerian children.
Memórias do Instituto Oswaldo Cruz 2008;103(8):754-9.
2008: Ahmed Adedeji; Fatai A Fehintola; N O Olasupo; T Balogun; Akintunde Sowunmi
Activities of artesunate and amodiaquine against intestinal helminth in children with Plasmodium falciparum malaria in endemic areas.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2008;27(7):627-9.
2008: Fatai A Fehintola; Ahmed Adedeji; Grace O Gbotosho; Christian T Happi; Sulaiman T Balogun; Onikepe Folarin; Abayomi O Sijuade; Akintunde Sowunmi
Effects of artesunate-cotrimoxazole and amodiaquine-artesunate against asexual and sexual stages of Plasmodium falciparum malaria in Nigerian children.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 2008;14(3):188-94.
2008: Akintunde Sowunmi; Grace O Gbotosho; Ahmed Adedeji; Ernest Tambo; Olayinka M Bolaji; Christian T Happi; Babasola A Fateye
Herpes simplex labialis in children with acute falciparum malaria.
Acta tropica 2008;106(1):68-71.
2008: Akintunde Sowunmi; Sulayman T Balogun; Grace O Gbotosho; Christian T Happi
Plasmodium falciparum gametocyte sex ratios in children with acute, symptomatic, uncomplicated infections treated with amodiaquine.
Malaria journal 2008;7():169.
2008: Akintunde Sowunmi; Tunde Balogun; Grace O Gbotosho; Christian T Happi; Ahmed Adedeji; Olayinka M Bolaji; Fatai A Fehintola; Onikepe Folarin
Activities of artemether-lumefantrine and amodiaquine-sulfalene-pyrimethamine against sexual-stage parasites in falciparum malaria in children.
Chemotherapy 2008;54(3):201-8.
2008: Grace O Gbotosho; Christian T Happi; A Sijuade; O A T Ogundahunsi; Akintunde Sowunmi; Ayoade Oduola
Comparative study of interactions between chloroquine and chlorpheniramine or promethazine in healthy volunteers: a potential combination-therapy phenomenon for resuscitating chloroquine for malaria treatment in Africa.
Annals of tropical medicine and parasitology 2008;102(1):3-9.
2007: Akintunde Sowunmi; Grace O Gbotosho; Christian T Happi; Ahmed Adedeji; Fatai A Fehintola; Onikepe Folarin; Ernest Tambo; Babasola A Fateye
Therapeutic efficacy and effects of artemether-lumefantrine and amodiaquine-sulfalene-pyrimethamine on gametocyte carriage in children with uncomplicated Plasmodium falciparum malaria in southwestern Nigeria.
The American journal of tropical medicine and hygiene 2007;77(2):235-41.
2007: Akintunde Sowunmi; Grace O Gbotosho; Ahmed Adedeji; Babasola A Fateye; Morenikeji F Sabitu; Christian T Happi; Fatai A Fehintola
Effects of acute Plasmodium falciparum malaria on body weight in children in an endemic area.
Parasitology research 2007;101(2):343-9.
2007: Akintunde Sowunmi; Grace O Gbotosho; Christian T Happi; Ahmed Adedeji; Olayinka M Bolaji; Fatai A Fehintola; Babasola A Fateye; Ayoade Oduola
Enhancement of the antimalarial efficacy of amodiaquine by chlorpheniramine in vivo.
Memórias do Instituto Oswaldo Cruz 2007;102(3):417-9.
2007: Akintunde Sowunmi; Tunde Balogun; Grace O Gbotosho; Christian T Happi; Ahmed Adedeji; Fatai A Fehintola
Activities of amodiaquine, artesunate, and artesunate-amodiaquine against asexual- and sexual-stage parasites in falciparum malaria in children.
Antimicrobial agents and chemotherapy 2007;51(5):1694-9.
2007: Akintunde Sowunmi; Grace O Gbotosho; Ahmed Adedeji; Ernest Tambo; Babasola A Fateye; Christian T Happi; A O J Amoo
The effects of artemether-lumefantrine vs amodiaquine-sulfalene-pyrimethamine on the hepatomegaly associated with Plasmodium falciparum malaria in children.
Parasitology research 2007;100(3):511-7.
2006: Fatai A Fehintola; Catherine O Falade; Akintunde Sowunmi
Intravascular haemolysis following treatment of malaria with halofantrine: case report.
Nigerian journal of clinical practice 2006;9(2):174-5.
2006: Akintunde Sowunmi; Ahmed Adedeji; Grace O Gbotosho; Babasola A Fateye; TC Happi
Effects of pyrimethamine-sulphadoxine, chloroquine plus chlorpheniramine, and amodiaquine plus pyrimethamine-sulphadoxine on gametocytes during and after treatment of acute, uncomplicated malaria in children.
Memórias do Instituto Oswaldo Cruz 2006;101(8):887-93.
2006: Christian T Happi; Grace O Gbotosho; Onikepe Folarin; Akintunde Sowunmi; Olayinka M Bolaji; Babasola A Fateye; Dennis E Kyle; Wilbur K Milhous; Dyann F Wirth; Ayoade Oduola
Linkage disequilibrium between two distinct loci in chromosomes 5 and 7 of Plasmodium falciparum and in vivo chloroquine resistance in Southwest Nigeria.
Parasitology research 2006;100(1):141-8.
2006: Grace O Gbotosho; O A T Ogundahunsi; Christian T Happi; Dennis E Kyle; Lucia Gerena; Wilbur K Milhous; Akintunde Sowunmi; Ayoade Oduola; Lateef A Salako
The effects of alpha1-acid glycoprotein on the reversal of chloroquine resistance in Plasmodium falciparum.
Annals of tropical medicine and parasitology 2006;100(7):571-8.
2006: Christian T Happi; Grace O Gbotosho; Onikepe Folarin; Olayinka M Bolaji; Akintunde Sowunmi; Dennis E Kyle; Wilbur K Milhous; Dyann F Wirth; Ayoade Oduola
Association between mutations in Plasmodium falciparum chloroquine resistance transporter and P. falciparum multidrug resistance 1 genes and in vivo amodiaquine resistance in P. falciparum malaria-infected children in Nigeria.
The American journal of tropical medicine and hygiene 2006;75(1):155-61.
2006: Akintunde Sowunmi; Grace O Gbotosho; Babasola A Fateye; Ahmed Adedeji
Predictors of the failure of treatment with trimethoprim-sulfamethoxazole in children with uncomplicated, Plasmodium falciparum malaria.
Annals of tropical medicine and parasitology 2006;100(3):205-11.
2006: Akintunde Sowunmi; Babasola A Fateye; Ahmed Adedeji; Grace O Gbotosho; TC Happi; Ayodele Bamgboye; Olayinka M Bolaji; Ayoade Oduola
Predictors of the failure of treatment with pyrimethamine-sulfadoxine in children with uncomplicated falciparum malaria.
Acta tropica 2006;98(1):6-14.
2006: Ahmed Adedeji; Babasola A Fateye; A O J Amoo; Akintunde Sowunmi
Response to chloroquine treatment in children with or without gametocytes during uncomplicated Plasmodium falciparum malaria.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 2006;25(2):126-8.
2006: Christian T Happi; Grace O Gbotosho; Onikepe Folarin; Danny Milner; Ousmane Sarr; Akintunde Sowunmi; Dennis E Kyle; Wilbur K Milhous; Dyann F Wirth; Ayoade Oduola
Confirmation of emergence of mutations associated with atovaquone-proguanil resistance in unexposed Plasmodium falciparum isolates from Africa.
Malaria journal 2006;5():82.
2005: Akintunde Sowunmi; Fatai A Fehintola; Ahmed Adedeji; Grace O Gbotosho; Ernest Tambo; Babasola A Fateye; TC Happi; Ayoade Oduola
Open randomized study of artesunate-amodiaquine vs. chloroquine-pyrimethamine-sulfadoxine for the treatment of uncomplicated Plasmodium falciparum malaria in Nigerian children.
Tropical medicine & international health : TM & IH 2005;10(11):1161-70.
2005: Ahmed Adedeji; Fatai A Fehintola; Babasola A Fateye; TC Happi; A O J Amoo; Grace O Gbotosho; Akintunde Sowunmi
Plasmodium falciparum malaria in Nigerian children during high and low transmission seasons: gametocyte carriage and response to oral chloroquine.
Journal of tropical pediatrics 2005;51(5):288-94.
2005: Akintunde Sowunmi; Babasola A Fateye; Ahmed Adedeji; Fatai A Fehintola; Grace O Gbotosho; TC Happi; Ernest Tambo; Ayoade Oduola
Predictors of the failure of treatment with chloroquine in children with acute, uncomplicated, Plasmodium falciparum malaria, in an area with high and increasing incidences of chloroquine resistance.
Annals of tropical medicine and parasitology 2005;99(6):535-44.
2005: Christian T Happi; Grace O Gbotosho; Onikepe Folarin; Dora O Akinboye; Bidemi O Yusuf; OO Ebong; Akintunde Sowunmi; Dennis E Kyle; Wilbur K Milhous; Dyann F Wirth; Ayoade Oduola
Polymorphisms in Plasmodium falciparum dhfr and dhps genes and age related in vivo sulfadoxine-pyrimethamine resistance in malaria-infected patients from Nigeria.
Acta tropica 2005;95(3):183-93.
2005: Akintunde Sowunmi; Babasola A Fateye; Ahmed Adedeji; Fatai A Fehintola; Ayodele Bamgboye; Chinedum Babalola; TC Happi; Grace O Gbotosho
Effects of antifolates--co-trimoxazole and pyrimethamine-sulfadoxine--on gametocytes in children with acute, symptomatic, uncomplicated, Plasmodium falciparum malaria.
Memórias do Instituto Oswaldo Cruz 2005;100(4):451-5.
2005: Akintunde Sowunmi; Babasola A Fateye; Ahmed Adedeji; Fatai A Fehintola; Grace O Gbotosho; TC Happi; Ayoade Oduola
Predictors of the failure of treatment with chloroquine plus chlorpheniramine, in children with acute, uncomplicated, Plasmodium falciparum malaria.
Annals of tropical medicine and parasitology 2005;99(4):331-8.
2004: Akintunde Sowunmi; Ahmed Adedeji; Babasola A Fateye; Fatai A Fehintola
Comparative effects of pyrimethamine-sulfadoxine, with and without probenecid, on Plasmodium falciparum gametocytes in children with acute, uncomplicated malaria.
Annals of tropical medicine and parasitology 2004;98(8):873-8.
2004: Akintunde Sowunmi; Ahmed Adedeji; Babasola A Fateye; Chinedum Babalola
Plasmodium falciparum hyperparasitaemia in children. Risk factors, treatment outcomes, and gametocytaemia following treatment.
Parasite (Paris, France) 2004;11(3):317-23.
2004: Akintunde Sowunmi; Babasola A Fateye; Ahmed Adedeji; Fatai A Fehintola; TC Happi
Risk factors for gametocyte carriage in uncomplicated falciparum malaria in children.
Parasitology 2004;129(Pt 3):255-62.
2004: Ali Alloueche; W Bailey; S Barton; J Bwika; Phillips Chimpeni; Catherine O Falade; Fatai A Fehintola; Richard John Horton; Shabbar Jaffar; Thomas P Kanyok; Song Le; James Kublin; T Lang; Michel A Missinou; C Mkandala; Ayoade Oduola; Zul Premji; L Robertson; Akintunde Sowunmi; S A Ward; Peter A Winstanley
Comparison of chlorproguanil-dapsone with sulfadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria in young African children: double-blind randomised controlled trial.
Lancet 2004;363(9424):1843-8.
2004: Edith Ajaiyeoba; Catherine O Falade; Olufunmilayo I Fawole; Dora O Akinboye; Grace O Gbotosho; Olayinka M Bolaji; JS Ashidi; OO Abiodun; OS Osowole; Oludele A Itiola; Oladimeji Oladepo; Akintunde Sowunmi; Ayoade Oduola
Efficacy of herbal remedies used by herbalists in Oyo State Nigeria for treatment of Plasmodium falciparum infections--a survey and an observation.
African journal of medicine and medical sciences 2004;33(2):115-9.
2004: Akintunde Sowunmi; Fatai A Fehintola; Ahmed Adedeji; Grace O Gbotosho; Catherine O Falade; Ernest Tambo; Babasola A Fateye; TC Happi; Ayoade Oduola
Open randomized study of pyrimethamine-sulphadoxine vs. pyrimethamine-sulphadoxine plus probenecid for the treatment of uncomplicated Plasmodium falciparum malaria in children.
Tropical medicine & international health : TM & IH 2004;9(5):606-14.
2004: O O Oduola; TC Happi; Grace O Gbotosho; O A T Ogundahunsi; Catherine O Falade; Dora O Akinboye; Akintunde Sowunmi; Ayoade Oduola
Plasmodium berghei: efficacy and safety of combinations of chloroquine and promethazine in chloroquine resistant infections in gravid mice.
African journal of medicine and medical sciences 2004;33(1):77-81.
2004: Christian T Happi; Grace O Gbotosho; Akintunde Sowunmi; Catherine O Falade; Dora O Akinboye; Oladimeji Oladepo; Ayoade Oduola
Malaria diagnosis: false negative parasight-F tests in falciparum malaria patients in Nigeria.
African journal of medicine and medical sciences 2004;33(1):15-8.
2004: Fatai A Fehintola; Ahmed Adedeji; Ernest Tambo; B B Fateye; TC Happi; Akintunde Sowunmi
Cotrimoxazole in the treatment of acute uncomplicated falciparum malaria in nigerian children : a controlled clinical trial.
Clinical drug investigation 2004;24(3):149-55.
2004: Christian T Happi; Grace O Gbotosho; Akintunde Sowunmi; Catherine O Falade; Dora O Akinboye; Lucia Gerena; Dennis E Kyle; Wilbur K Milhous; Dyann F Wirth; Ayoade Oduola
Molecular analysis of Plasmodium falciparum recrudescent malaria infections in children treated with chloroquine in Nigeria.
The American journal of tropical medicine and hygiene 2004;70(1):20-6.
2003: Akintunde Sowunmi; Babasola A Fateye
Changes in Plasmodium falciparum gametocytaemia in children with chloroquine-sensitive asexual infections.
Parasite (Paris, France) 2003;10(4):363-9.
2003: Chinedum Babalola; Gerhard K E Scriba; Akintunde Sowunmi; Olaniyi A Alawode
Liquid chromatographic determination of pyronaridine in human plasma and oral dosage form.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2003;795(2):265-72.
2003: Akintunde Sowunmi; Babasola A Fateye
Gametocyte sex ratios in children with asymptomatic, recrudescent, pyrimethamine-sulfadoxine-resistant, Plasmodium falciparum malaria.
Annals of tropical medicine and parasitology 2003;97(7):671-82.
2003: Akintunde Sowunmi; Babasola A Fateye
Plasmodium falciparum gametocytaemia in Nigerian children: before, during and after treatment with antimalarial drugs.
Tropical medicine & international health : TM & IH 2003;8(9):783-92.
2003: Akintunde Sowunmi; Babasola A Fateye
Asymptomatic, recrudescent, chloroquine-resistant Plasmodium falciparum infections in Nigerian children: clinical and parasitological characteristics and implications for the transmission of drug-resistant parasites.
Annals of tropical medicine and parasitology 2003;97(5):469-79.
2003: Akintunde Sowunmi; Babasola A Fateye; TC Happi; Grace O Gbotosho; Ayoade Oduola
Plasmodium falciparum gametocytaemia in Nigerian children: Peripheral immature gametocytaemia as an indicator of a poor response to chloroquine treatment, and its relationship to molecular determinants of chloroquine resistance.
Annals of tropical medicine and parasitology 2003;97(5):453-68.
2003: TC Happi; S M Thomas; Grace O Gbotosho; Catherine O Falade; Dora O Akinboye; Lucia Gerena; T Hudson; Akintunde Sowunmi; Dennis E Kyle; Wilbur K Milhous; Dyann F Wirth; Ayoade Oduola
Point mutations in the pfcrt and pfmdr-1 genes of Plasmodium falciparum and clinical response to chloroquine, among malaria patients from Nigeria.
Annals of tropical medicine and parasitology 2003;97(5):439-51.
2003: Akintunde Sowunmi
A randomized comparison of chloroquine and chloroquine plus ketotifen in the treatment of acute, uncomplicated, Plasmodium falciparum malaria in children.
Annals of tropical medicine and parasitology 2003;97(2):103-17.
2002: Fatai A Fehintola; Ahmed Adedeji; Akintunde Sowunmi
Comparative efficacy of chloroquine and cotrimoxazole in the treatment of acute uncomplicated falciparum malaria in Nigerian children.
The Central African journal of medicine 2002;48(9-10):101-5.
2002: Akintunde Sowunmi; Ahmed Adedeji
The effects of chloroquine, amodiaquine and chloroquine plus chlorpheniramine on the disposition kinetics of the hepatomegaly associated with acute, uncomplicated, Plasmodium falciparum malaria in children.
Annals of tropical medicine and parasitology 2002;96(6):543-51.
2002: Akintunde Sowunmi
A randomized comparison of chloroquine, amodiaquine and their combination with pyrimethamine-sulfadoxine in the treatment of acute, uncomplicated, Plasmodium falciparum malaria in children.
Annals of tropical medicine and parasitology 2002;96(3):227-38.
2001: Akintunde Sowunmi; Adegoke G Falade; Ahmed Adedeji; Catherine O Falade
Comparative clinical characteristics and responses to oral 4-aminoquinoline therapy of malarious children who did and did not develop 4-aminoquinoline-induced pruritus.
Annals of tropical medicine and parasitology 2001;95(7):645-53.
2001: Akintunde Sowunmi; A I Ayede; Adegoke G Falade; V N Ndikum; CO Sowunmi; Ahmed Adedeji; Catherine O Falade; TC Happi; Ayoade Oduola
Randomized comparison of chloroquine and amodiaquine in the treatment of acute, uncomplicated, Plasmodium falciparum malaria in children.
Annals of tropical medicine and parasitology 2001;95(6):549-58.
2001: OO Akinyinka; Akintunde Sowunmi; R Honeywell; AG Renwick
Urinary recovery of caffeine and its metabolites in healthy African children.
African journal of medicine and medical sciences 2001;30(1-2):1-4.
2001: Akintunde Sowunmi; Ahmed Adedeji; CO Sowunmi; Catherine O Falade; Adegoke G Falade; BM Ohaeri; TC Happi; Ayoade Oduola
Clinical characteristics and disposition kinetics of the hepatomegaly associated with acute, uncomplicated, Plasmodium falciparum malaria in children.
Annals of tropical medicine and parasitology 2001;95(1):7-18.
2000: JA Olowu; Akintunde Sowunmi; A E Abohweyere
Congenital malaria in a hyperendemic area: a revisit.
African journal of medicine and medical sciences 2000;29(3-4):211-3.
2000: Akintunde Sowunmi; Ahmed Adedeji; CO Sowunmi; Adegoke G Falade; A O Sijuade; Ayoade Oduola
Comparative clinical characteristics and response to oral antimalarial therapy of children with and without Plasmodium falciparum hyperparasitaemia in an endemic area.
Annals of tropical medicine and parasitology 2000;94(6):549-58.
2000: OO Akinyinka; Akintunde Sowunmi; R Honeywell; AG Renwick
The effects of acute falciparum malaria on the disposition of caffeine and the comparison of saliva and plasma-derived pharmacokinetic parameters in adult Nigerians.
European journal of clinical pharmacology 2000;56(2):159-65.
2000: OO Akinyinka; Akintunde Sowunmi; R Honeywell; AG Renwick
The pharmacokinetics of caffeine in Nigerian children suffering from malaria and kwashiorkor.
European journal of clinical pharmacology 2000;56(2):153-8.
2000: Akintunde Sowunmi; Fatai A Fehintola; Ahmed Adedeji; Adegoke G Falade; Catherine O Falade; OO Akinyinka; Ayoade Oduola
Comparative efficacy of chloroquine plus chlorpheniramine alone and in a sequential combination with sulfadoxine-pyrimethamine, for the treatment of acute, uncomplicated, falciparum malaria in children.
Annals of tropical medicine and parasitology 2000;94(3):209-17.
2000: Akintunde Sowunmi; O A T Ogundahunsi; Catherine O Falade; Grace O Gbotosho; Ayoade Oduola
Gastrointestinal manifestations of acute falciparum malaria in children.
Acta tropica 2000;74(1):73-6.
1999: Akintunde Sowunmi; Fatai A Fehintola; O A T Ogundahunsi; A B Ofi; TC Happi; Ayoade Oduola
Comparative cardiac effects of halofantrine and chloroquine plus chlorpheniramine in children with acute uncomplicated falciparum malaria.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1999;93(1):78-83.
1998: Akintunde Sowunmi; Fatai A Fehintola; O A T Ogundahunsi; Ayodele O Arowojolu; Ayoade Oduola
Efficacy of chloroquine plus chlorpheniramine in chloroquine-resistant falciparum malaria during pregnancy in Nigerian women: a preliminary study.
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 1998;18(6):524-7.
1998: Akintunde Sowunmi; Ayoade Oduola; O A T Ogundahunsi; Fatai A Fehintola; O A Ilesanmi; OO Akinyinka; Ayodele O Arowojolu
Randomised trial of artemether versus artemether and mefloquine for the treatment of chloroquine/sufadoxine-pyrimethamine-resistant falciparum malaria during pregnancy.
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 1998;18(4):322-7.
1998: Akintunde Sowunmi; Catherine O Falade; Ayoade Oduola; O A T Ogundahunsi; Fatai A Fehintola; Grace O Gbotosho; P Larcier; Lateef A Salako
Cardiac effects of halofantrine in children suffering from acute uncomplicated falciparum malaria.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1998;92(4):446-8.
1998: Akintunde Sowunmi; Fatai A Fehintola; O A T Ogundahunsi; Ayoade Oduola
Comparative efficacy of chloroquine plus chlorpheniramine and halofantrine in acute uncomplicated falciparum malaria in Nigerian children.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1998;92(4):441-5.
1998: Chinedum Babalola; Oluseye O Bolaji; Festus A Ogunbona; Akintunde Sowunmi; O Walker
Pharmacokinetics of quinine in African patients with acute falciparum malaria.
Pharmacy world & science : PWS 1998;20(3):118-22.
1998: Akintunde Sowunmi; Ayoade Oduola
Viability of Plasmodium falciparum ex vivo: comparison of the effects of artemether and sulfadoxine-pyrimethamine.
European journal of clinical pharmacology 1998;54(3):221-6.
1998: Ayoade Oduola; Akintunde Sowunmi; Wilbur K Milhous; Thomas G Brewer; Dennis E Kyle; Lucia Gerena; RN Rossan; Lateef A Salako; BG Schuster
In vitro and in vivo reversal of chloroquine resistance in Plasmodium falciparum with promethazine.
The American journal of tropical medicine and hygiene 1998;58(5):625-9.
1998: Akintunde Sowunmi; Ayoade Oduola; O A T Ogundahunsi; Lateef A Salako
Enhancement of the antimalarial effect of chloroquine by chloropheniramine in vivo.
Tropical medicine & international health : TM & IH 1998;3(3):177-83.
1998: Akintunde Sowunmi; Ayoade Oduola; O A T Ogundahunsi; Lateef A Salako
Comparative efficacy of chloroquine plus chlorpheniramine and pyrimethamine/sulfadoxine in acute uncomplicated falciparum malaria in Nigerian children.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1998;92(1):77-81.
1997: Akintunde Sowunmi; Ayoade Oduola
Comparative efficacy of chloroquine/chlorpheniramine combination and mefloquine for the treatment of chloroquine-resistant Plasmodium falciparum malaria in Nigerian children.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1997;91(6):689-93.
1997: Ayoade Oduola; G O Omitowoju; Akintunde Sowunmi; Michael T Makler; Catherine O Falade; Dennis E Kyle; Fatai A Fehintola; O A T Ogundahunsi; Robert C Piper; BG Schuster; Wilbur K Milhous
Plasmodium falciparum: evaluation of lactate dehydrogenase in monitoring therapeutic responses to standard antimalarial drugs in Nigeria.
Experimental parasitology 1997;87(3):283-9.
1997: Akintunde Sowunmi; A M Odulola
Artemether treatment of recrudescent Plasmodium falciparum malaria in children.
Tropical medicine & international health : TM & IH 1997;2(7):631-4.
1997: Akintunde Sowunmi
Clinical study of cerebral malaria in African children.
African journal of medicine and medical sciences 1997;26(1-2):9-11.
1997: Akintunde Sowunmi; Ayoade Oduola; O A T Ogundahunsi; Catherine O Falade; Grace O Gbotosho; Lateef A Salako
Enhanced efficacy of chloroquine-chlorpheniramine combination in acute uncomplicated falciparum malaria in children.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1997;91(1):63-7.
1997: Catherine O Falade; Lateef A Salako; Akintunde Sowunmi; Ayoade Oduola; P Larcier
Comparative efficacy of halofantrine, chloroquine and sulfadoxine-pyrimethamine for treatment of acute uncomplicated falciparum malaria in Nigerian children.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1997;91(1):58-62.
1996: Akintunde Sowunmi; O Walker; Lateef A Salako
Amlodipine as monotherapy in hypertensive Africans: clinical efficacy and safety studies.
African journal of medicine and medical sciences 1996;25(3):213-6.
1996: Akintunde Sowunmi
Hepatomegaly in acute falciparum malaria in children.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1996;90(5):540-2.
1996: Akintunde Sowunmi
Disposition of oral quinine in African patients suffering from acute uncomplicated falciparum malaria.
East African medical journal 1996;73(8):519-23.
1996: Akintunde Sowunmi; Ayoade Oduola
Efficacy of artemether in severe falciparum malaria in African children.
Acta tropica 1996;61(1):57-63.
1996: Akintunde Sowunmi; Lateef A Salako; O Walker
Open trial of doxazosin in hypertensive Africans: dose finding, efficacy and safety studies.
African journal of medicine and medical sciences 1996;25(1):53-9.
1996: Akintunde Sowunmi
Hyponatraemia in severe falciparum malaria: a clinical study of nineteen comatose African children.
African journal of medicine and medical sciences 1996;25(1):47-52.
1996: Akintunde Sowunmi; Ayoade Oduola; AO Ilesanmi; Lateef A Salako
Open comparison of artemether and mefloquine in uncomplicated Plasmodium falciparum hyperparasitaemia in children.
Annals of tropical paediatrics 1996;16(1):5-9.
1996: Akintunde Sowunmi
Disposition of quinine in plasma after a single oral and intramuscular dose in healthy adult Africans.
East African medical journal 1996;73(2):111-4.
1996: Akintunde Sowunmi; Lateef A Salako
Effect of dose size on the pharmacokinetics of orally administered quinine.
European journal of clinical pharmacology 1996;49(5):383-6.
1995: Akintunde Sowunmi; T J Rashid; OO Akinyinka; A G Renwick
Ethnic differences in nifedipine kinetics: comparisons between Nigerians, Caucasians and South Asians.
British journal of clinical pharmacology 1995;40(5):489-93.
1995: Akintunde Sowunmi; Ayoade Oduola; Lateef A Salako
Artemether treatment of sulfadoxine/pyrimethamine-resistant Plasmodium falciparum malaria in children.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1995;89(4):435-6.
1995: Akintunde Sowunmi
Body temperature and malaria parasitaemia in rural African children.
East African medical journal 1995;72(7):427-30.
1995: Akintunde Sowunmi; J A Akindele; M A Balogun
Leukocyte counts in falciparum malaria in African children from an endemic area.
African journal of medicine and medical sciences 1995;24(2):145-9.
1995: Akintunde Sowunmi; Ayoade Oduola
Open comparison of mefloquine, mefloquine/sulfadoxine/pyrimethamine and chloroquine in acute uncomplicated falciparum malaria in children.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1995;89(3):303-5.
1995: R Reber-Liske; Lateef A Salako; Hugues Matile; Akintunde Sowunmi; D Stürchler
[NANP]19-5.1. A malaria vaccine field trial in Nigerian children.
Tropical and geographical medicine 1995;47(2):61-3.
1995: Akintunde Sowunmi; R A Adio; Ayoade Oduola; O A T Ogundahunsi; Lateef A Salako
Acute psychosis after mefloquine. Report of six cases.
Tropical and geographical medicine 1995;47(4):179-80.
1995: Akintunde Sowunmi; Jude U Ohaeri; Catherine O Falade
Falciparum malaria presenting as psychosis.
Tropical and geographical medicine 1995;47(5):218-9.
1994: Akintunde Sowunmi
Acute psychosis after mefloquine: a case report.
East African medical journal 1994;71(12):818-9.
1994: Akintunde Sowunmi; Lateef A Salako; F A Ogunbona
Bioavailability of sulphate and dihydrochloride salts of quinine.
African journal of medicine and medical sciences 1994;23(3):275-8.
1994: Lateef A Salako; O Walker; Akintunde Sowunmi; S J Omokhodion; R Adio; Ayoade Oduola
Artemether in moderately severe and cerebral malaria in Nigerian children.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1994;88 Suppl 1():S13-5.
1994: Lateef A Salako; O Walker; Akintunde Sowunmi
Parenteral therapy of moderately severe malaria: comparison of intramuscular artemether and intramuscular sulfadoxine-pyrimethamine.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1994;88(1):89-91.
1993: O Walker; Lateef A Salako; S I Omokhodion; Akintunde Sowunmi
An open randomized comparative study of intramuscular artemether and intravenous quinine in cerebral malaria in children.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1993;87(5):564-6.
1993: Akintunde Sowunmi
Psychosis after cerebral malaria in children.
Journal of the National Medical Association 1993;85(9):695-6.
1993: Akintunde Sowunmi; J A Akindele; G O Omitowoju; Akinyinka O Omigbodun; Ayoade Oduola; Lateef A Salako
Intramuscular sulfadoxine-pyrimethamine in uncomplicated chloroquine-resistant falciparum malaria during pregnancy.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1993;87(4):472.
1993: Akintunde Sowunmi; Lateef A Salako; Ayoade Oduola; O Walker; J A Akindele; O A T Ogundahunsi
Neuropsychiatric side effects of mefloquine in Africans.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1993;87(4):462-3.
1993: Akintunde Sowunmi; J A Akindele
Presumptive diagnosis of malaria in infants in an endemic area.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1993;87(4):422.
1993: Akintunde Sowunmi; O Walker; Lateef A Salako
Cerebral malaria in non-paediatric subjects resident in southwestern Nigeria.
African journal of medicine and medical sciences 1993;22(1):49-53.
1993: Ayoade Oduola; G O Omitowoju; Lucia Gerena; Dennis E Kyle; Wilbur K Milhous; Akintunde Sowunmi; Lateef A Salako
Reversal of mefloquine resistance with penfluridol in isolates of Plasmodium falciparum from south-west Nigeria.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1993;87(1):81-3.
1993: J A Akindele; Akintunde Sowunmi; A E Abohweyere
Congenital malaria in a hyperendemic area: a preliminary study.
Annals of tropical paediatrics 1993;13(3):273-6.
1992: Lateef A Salako; R A Adio; O Walker; Akintunde Sowunmi; D Stürchler; M L Mittelholzer; R Reber-Liske; U Dickschat
Mefloquine-sulphadoxine-pyrimethamine (Fansimef, Roche) in the prophylaxis of Plasmodium falciparum malaria: a double-blind, comparative, placebo-controlled study.
Annals of tropical medicine and parasitology 1992;86(6):575-81.
1992: Akintunde Sowunmi; O Walker; J A Akindele
Severe falciparum malaria: survival with oral therapy.
Tropical and geographical medicine 1992;44(4):352-4.
1992: O Walker; Lateef A Salako; Akintunde Sowunmi; J O Thomas; O Sodeine; F S Bondi
Prognostic risk factors and post mortem findings in cerebral malaria in children.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1992;86(5):491-3.
1992: Akintunde Sowunmi; Ayoade Oduola; Lateef A Salako; O A T Ogundahunsi; O J Laoye; O Walker
The relationship between the response of Plasmodium falciparum malaria to mefloquine in African children and its sensitivity in vitro.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1992;86(4):368-71.
1992: Ayoade Oduola; Akintunde Sowunmi; Wilbur K Milhous; Dennis E Kyle; R K Martin; O Walker; Lateef A Salako
Innate resistance to new antimalarial drugs in Plasmodium falciparum from Nigeria.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1992;86(2):123-6.
1992: Akintunde Sowunmi; Lateef A Salako
Evaluation of the relative efficacy of various antimalarial drugs in Nigerian children under five years of age suffering from acute uncomplicated falciparum malaria.
Annals of tropical medicine and parasitology 1992;86(1):1-8.
1992: Lateef A Salako; Akintunde Sowunmi
Disposition of quinine in plasma, red blood cells and saliva after oral and intravenous administration to healthy adult Africans.
European journal of clinical pharmacology 1992;42(2):171-4.
1992: Akintunde Sowunmi; O Walker; Lateef A Salako
Hyperparasitaemia: not a reliable indicator of severity or poor prognosis in falciparum malaria in children in endemic African countries.
Annals of tropical paediatrics 1992;12(2):155-8.
1991: Akintunde Sowunmi; F O Akinbami
Body temperature in apparently healthy African children under 10 years of age.
African journal of medicine and medical sciences 1991;20(2):97-9.
1991: F O Akinbami; Akintunde Sowunmi
Body temperature in the Nigerian neonate--comparison of axillary and rectal temperatures.
African journal of medicine and medical sciences 1991;20(1):49-52.
1990: Akintunde Sowunmi; Lateef A Salako; O Walker; O A T Ogundahunsi
Clinical efficacy of mefloquine in children suffering from chloroquine-resistant Plasmodium falciparum malaria in Nigeria.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1990;84(6):761-4.
1990: Lateef A Salako; F O Ajayi; Akintunde Sowunmi; O Walker
Malaria in Nigeria: a revisit.
Annals of tropical medicine and parasitology 1990;84(5):435-45.
1990: Lateef A Salako; Akintunde Sowunmi; O Walker
Evaluation of the clinical efficacy and safety of halofantrine in falciparum malaria in Ibadan, Nigeria.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1990;84(5):644-7.
1990: Lateef A Salako; R A Adio; Akintunde Sowunmi; O Walker
Parenteral sulphadoxine-pyrimethamine (Fansidar): an effective and safe but under-used method of anti-malarial treatment.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1990;84(5):641-3.
1990: Akintunde Sowunmi; Lateef A Salako; O J Laoye; A F Aderounmu
Combination of quinine, quinidine and cinchonine for the treatment of acute falciparum malaria: correlation with the susceptibility of Plasmodium falciparum to the cinchona alkaloids in vitro.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1990;84(5):626-9.
1989: Lateef A Salako; Akintunde Sowunmi; F O Akinbami
Pharmacokinetics of quinine in African children suffering from kwashiorkor.
British journal of clinical pharmacology 1989;28(2):197-201.
1988: Lateef A Salako; Akintunde Sowunmi; O J Laoye
Evaluation of the sensitivity in vivo and in vitro of Plasmodium falciparum malaria to quinine in an area of full sensitivity to chloroquine.
Transactions of the Royal Society of Tropical Medicine and Hygiene 1988;82(3):366-8.