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Abigail Soyombo

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Chemicals & Drugs

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Soichiro Yamaguchi; Sandip Patel; Abigail A Soyombo; Eugen Brailoiu; Dev Churamani; George Dickinson; Archana Jha; Qin Li; Shmuel Muallem
Transient receptor potential mucolipin 1 (TRPML1) and two-pore channels are functionally independent organellar ion channels.
Manjari Chandra; Hua Zhou; Qin Li; Shmuel Muallem; Hofmann Sandra; Abigail A Soyombo
A role for the Ca2+ channel TRPML1 in gastric acid secretion, based on analysis of knockout mice.
Hyun Jin Kim; Abigail A Soyombo; Sandra Tjon-Kon-Sang; Insuk So; Shmuel Muallem
The Ca(2+) channel TRPML3 regulates membrane trafficking and autophagy.

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All Publications

2011: Soichiro Yamaguchi; Sandip Patel; Abigail A Soyombo; Eugen Brailoiu; Dev Churamani; George Dickinson; Archana Jha; Qin Li; Shmuel Muallem
Transient receptor potential mucolipin 1 (TRPML1) and two-pore channels are functionally independent organellar ion channels.
The Journal of biological chemistry 2011;286(26):22934-42.
2011: Manjari Chandra; Hua Zhou; Qin Li; Shmuel Muallem; Hofmann Sandra; Abigail A Soyombo
A role for the Ca2+ channel TRPML1 in gastric acid secretion, based on analysis of knockout mice.
Gastroenterology 2011;140(3):857-67.
2009: Hyun Jin Kim; Abigail A Soyombo; Sandra Tjon-Kon-Sang; Insuk So; Shmuel Muallem
The Ca(2+) channel TRPML3 regulates membrane trafficking and autophagy.
Traffic (Copenhagen, Denmark) 2009;10(8):1157-67.
2008: Hyun Jin Kim; Qin Li; Sandra Tjon-Kon-Sang; Insuk So; Kirill Kiselyov; Abigail A Soyombo; Shmuel Muallem
A novel mode of TRPML3 regulation by extracytosolic pH absent in the varitint-waddler phenotype.
The EMBO journal 2008;27(8):1197-205.
2007: Kirill Kiselyov; Abigail A Soyombo; Shmuel Muallem
TRPpathies.
The Journal of physiology 2007;578(Pt 3):641-53.
2006: Youxue Wang; Abigail A Soyombo; Nikolay Shcheynikov; Weizhong Zeng; Michael R Dorwart; Christopher R Marino; Philip J Thomas; Shmuel Muallem
Slc26a6 regulates CFTR activity in vivo to determine pancreatic duct HCO3- secretion: relevance to cystic fibrosis.
The EMBO journal 2006;25(21):5049-57.
2006: Abigail A Soyombo; Sandra Tjon-Kon-Sang; Youssef Rbaibi; Enkelejda Bashllari; Jill Bisceglia; Shmuel Muallem; Kirill Kiselyov
TRP-ML1 regulates lysosomal pH and acidic lysosomal lipid hydrolytic activity.
The Journal of biological chemistry 2006;281(11):7294-301.
2005: Kirill Kiselyov; Jin Chen; Youssef Rbaibi; Daniel Oberdick; Sandra Tjon-Kon-Sang; Nikolay Shcheynikov; Shmuel Muallem; Abigail A Soyombo
TRP-ML1 is a lysosomal monovalent cation channel that undergoes proteolytic cleavage.
The Journal of biological chemistry 2005;280(52):43218-23.
2005: Vaibhav Katkade; Abigail A Soyombo; Irma Isordia-Salas; Harlan N Bradford; John P Gaughan; Robert W Colman; Tracee S Panetti
Domain 5 of cleaved high molecular weight kininogen inhibits endothelial cell migration through Akt.
Thrombosis and haemostasis 2005;94(3):606-14.
2005: Xinhua Wang; Weizhong Zeng; Abigail A Soyombo; Wei Tang; Elliott M Ross; Anthony P Barnes; Sharon L Milgram; Josef M Penninger; Patrick B Allen; Paul Greengard; Shmuel Muallem
Spinophilin regulates Ca2+ signalling by binding the N-terminal domain of RGS2 and the third intracellular loop of G-protein-coupled receptors.
Nature cell biology 2005;7(4):405-11.
2004: Shigeru B H Ko; Weizhong Zeng; Michael R Dorwart; Xiang Luo; Kil Hwan Kim; Linda Millen; Hidemi Goto; Satoru Naruse; Abigail A Soyombo; Philip J Thomas; Shmuel Muallem
Gating of CFTR by the STAS domain of SLC26 transporters.
Nature cell biology 2004;6(4):343-50.
2003: Praveena Gupta; Abigail A Soyombo; John M Shelton; Ian G Wilkofsky; Krystyna E Wisniewski; James A Richardson; Hofmann Sandra
Disruption of PPT2 in mice causes an unusual lysosomal storage disorder with neurovisceral features.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(21):12325-30.
2001: Praveena Gupta; Abigail A Soyombo; A Atashband; Krystyna E Wisniewski; John M Shelton; James A Richardson; Robert E Hammer; Hofmann Sandra
Disruption of PPT1 or PPT2 causes neuronal ceroid lipofuscinosis in knockout mice.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(24):13566-71.
2001: Hofmann Sandra; Amit K Das; Jui-Yun Lu; Abigail A Soyombo
Positional candidate gene cloning of CLN1.
Advances in genetics 2001;45():69-92.
1999: Abigail A Soyombo; W Yi; Hofmann Sandra
Structure of the human palmitoyl-protein thioesterase-2 gene (PPT2) in the major histocompatibility complex on chromosome 6p21.3.
Genomics 1999;56(2):208-16.
1997: Abigail A Soyombo; Hofmann Sandra
Molecular cloning and expression of palmitoyl-protein thioesterase 2 (PPT2), a homolog of lysosomal palmitoyl-protein thioesterase with a distinct substrate specificity.
The Journal of biological chemistry 1997;272(43):27456-63.