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Roberta Spaccapelo

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Roberto Galizi; Maria Angela Giubilei; Alessandro Magini; Tetsuhiro Ogawa; Roberta Spaccapelo; Furio Spano; Lorena Urbanelli; Barbara Capuccini; Jitender P Dubey; Carla Emiliani; Manlio Di Cristina
Evidence of tRNA cleavage in apicomplexan parasites: Half-tRNAs as new potential regulatory molecules of Toxoplasma gondii and Plasmodium berghei.
Erica M Pasini; Roberta Spaccapelo; Alan W Thomas; Elena Aime; Matt Berriman; Joanna A Braks; Jannik Fonager; Jan A Hiss; Chris J Janse; Onny Klop; Clemens H M Kocken; Matthias Mann; Thomas D Otto; Blandine Franke-Fayard
Proteomic and genetic analyses demonstrate that Plasmodium berghei blood stages export a large and diverse repertoire of proteins.
Tania Dottorini; Pietro Palladino; Tania Persampieri; Nicola Senin; Roberta Spaccapelo; Dean A Baker; Andrea Crisanti
Regulation of Anopheles gambiae male accessory gland genes influences postmating response in female.

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2013: Roberto Galizi; Maria Angela Giubilei; Alessandro Magini; Tetsuhiro Ogawa; Roberta Spaccapelo; Furio Spano; Lorena Urbanelli; Barbara Capuccini; Jitender P Dubey; Carla Emiliani; Manlio Di Cristina
Evidence of tRNA cleavage in apicomplexan parasites: Half-tRNAs as new potential regulatory molecules of Toxoplasma gondii and Plasmodium berghei.
Molecular and biochemical parasitology 2013;188(2):99-108.
2013: Erica M Pasini; Roberta Spaccapelo; Alan W Thomas; Elena Aime; Matt Berriman; Joanna A Braks; Jannik Fonager; Jan A Hiss; Chris J Janse; Onny Klop; Clemens H M Kocken; Matthias Mann; Thomas D Otto; Blandine Franke-Fayard
Proteomic and genetic analyses demonstrate that Plasmodium berghei blood stages export a large and diverse repertoire of proteins.
Molecular & cellular proteomics : MCP 2013;12(2):426-48.
2013: Tania Dottorini; Pietro Palladino; Tania Persampieri; Nicola Senin; Roberta Spaccapelo; Dean A Baker; Andrea Crisanti
Regulation of Anopheles gambiae male accessory gland genes influences postmating response in female.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2013;27(1):86-97.
2013: Joanna Braks; Chris J Janse; Onny Klop; Roberta Spaccapelo; Elena Aime; Blandine Franke-Fayard
Bioluminescence imaging of P. berghei Schizont sequestration in rodents.
Methods in molecular biology (Clifton, N.J.) 2013;923():353-68.
2012: Tania Dottorini; Pietro Palladino; Tania Persampieri; Roberta Spaccapelo; Andrea Crisanti
Silencing of the Hsf gene, the transcriptional regulator of A. gambiae male accessory glands, inhibits the formation of the mating plug in mated females and disrupts their monogamous behaviour.
Pathogens and global health 2012;106(7):405-12.
2012: Stephen A Kaba; Clara Brando; Peter Burkhard; Andrea Crisanti; Debleena Dasgupta; Tais A P F Doll; Qin Guo; Margaret E McCoy; Christian Mittelholzer; Roberta Spaccapelo; Yongkun Yang; David Lanar
Protective antibody and CD8+ T-cell responses to the Plasmodium falciparum circumsporozoite protein induced by a nanoparticle vaccine.
PloS one 2012;7(10):e48304.
2012: Cassandra Aldrich; Francesco Bistoni; Andrea Crisanti; Tania Dottorini; Carla Emiliani; Alessandro Magini; Roberta Spaccapelo
Roles of the amino terminal region and repeat region of the Plasmodium berghei circumsporozoite protein in parasite infectivity.
PloS one 2012;7(2):e32524.
2011: Roberta Spaccapelo; Manlio Di Cristina; Tania Dottorini; Mario Rende; Elena Aime; Paola Arcidiacono; Francesco Bistoni; Barbara Capuccini; Sara Caterbi; Andrea Crisanti
Disruption of plasmepsin-4 and merozoites surface protein-7 genes in Plasmodium berghei induces combined virulence-attenuated phenotype.
Scientific reports 2011;1():39.
2010: Manlio Di Cristina; Luisa Nunziangeli; Maria Angela Giubilei; Barbara Capuccini; Lorenzo d'Episcopo; Giorgio Mazzoleni; Francesca Baldracchini; Roberta Spaccapelo; Andrea Crisanti
An antigen microarray immunoassay for multiplex screening of mouse monoclonal antibodies.
Nature protocols 2010;5(12):1932-44.
2010: Roberta Spaccapelo; Chris J Janse; Sara Caterbi; Blandine Franke-Fayard; J Alfredo Bonilla; Luke M Syphard; Manlio Di Cristina; Tania Dottorini; Andrea Savarino; Antonio Cassone; Francesco Bistoni; Andrew P Waters; John B Dame; Andrea Crisanti
Plasmepsin 4-deficient Plasmodium berghei are virulence attenuated and induce protective immunity against experimental malaria.
The American journal of pathology 2010;176(1):205-17.
2009: Brice Enjalbert; Anna Rachini; Govindsamy Vediyappan; Donatella Pietrella; Roberta Spaccapelo; Anna Vecchiarelli; Alistair J P Brown; Christophe d'Enfert
A multifunctional, synthetic Gaussia princeps luciferase reporter for live imaging of Candida albicans infections.
Infection and immunity 2009;77(11):4847-58.
2008: Manlio Di Cristina; Daniela Marocco; Roberto Galizi; Carla Proietti; Roberta Spaccapelo; Andrea Crisanti
Temporal and spatial distribution of Toxoplasma gondii differentiation into Bradyzoites and tissue cyst formation in vivo.
Infection and immunity 2008;76(8):3491-501.
2007: Ermanno Federici; Vanessa Leonardi; Maria A Giubilei; Daniele Quaratino; Roberta Spaccapelo; Alessandro D'Annibale; Maurizio Petruccioli
Addition of allochthonous fungi to a historically contaminated soil affects both remediation efficiency and bacterial diversity.
Applied microbiology and biotechnology 2007;77(1):203-11.
2002: Rita Tewari; Roberta Spaccapelo; Francesco Bistoni; Anthony A Holder; Andrea Crisanti
Function of region I and II adhesive motifs of Plasmodium falciparum circumsporozoite protein in sporozoite motility and infectivity.
The Journal of biological chemistry 2002;277(49):47613-8.
2000: Manlio Di Cristina; Roberta Spaccapelo; Dominique Soldati; Francesco Bistoni; Andrea Crisanti
Two conserved amino acid motifs mediate protein targeting to the micronemes of the apicomplexan parasite Toxoplasma gondii.
Molecular and cellular biology 2000;20(19):7332-41.
2000: K Wengelnik; Roberta Spaccapelo; S Naitza; Andrea Crisanti
Structure-function analysis of malaria proteins by gene targeting--a response.
Parasitology today (Personal ed.) 2000;16(6):224-5.
1999: K Wengelnik; Roberta Spaccapelo; S Naitza; K J Robson; C J Janse; Francesco Bistoni; A P Waters; Andrea Crisanti
The A-domain and the thrombospondin-related motif of Plasmodium falciparum TRAP are implicated in the invasion process of mosquito salivary glands.
The EMBO journal 1999;18(19):5195-204.
1997: Roberta Spaccapelo; S Naitza; Kathryn J H Robson; Andrea Crisanti
Thrombospondin-related adhesive protein (TRAP) of Plasmodium berghei and parasite motility.
Lancet 1997;350(9074):335.
1997: Luigina Romani; Antonella Mencacci; Elio Cenci; Roberta Spaccapelo; G Del Sero; Ildo Nicoletti; Giorgio Trinchieri; Francesco Bistoni; Paolo Puccetti
Neutrophil production of IL-12 and IL-10 in candidiasis and efficacy of IL-12 therapy in neutropenic mice.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(11):5349-56.
1997: Roberta Spaccapelo; G Del Sero; Paolo Mosci; Francesco Bistoni; Luigina Romani
Early T cell unresponsiveness in mice with candidiasis and reversal by IL-2: effect on T helper cell development.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(5):2294-302.
1996: Antonella Mencacci; Roberta Spaccapelo; G Del Sero; K H Enssle; Antonio Cassone; Francesco Bistoni; Luigina Romani
CD4+ T-helper-cell responses in mice with low-level Candida albicans infection.
Infection and immunity 1996;64(12):4907-14.
1996: Antonella Mencacci; Elio Cenci; Roberta Spaccapelo; L Tonnetti; G Del Sero; Cristiana Fe' d'Ostiani; Francesco Bistoni; Luigina Romani
Neutrophils producing interleukin-10 antagonize the effect of interleukin-12 in mice with candidiasis.
Annals of the New York Academy of Sciences 1996;795():394-6.
1996: Luigina Romani; Antonella Mencacci; Elio Cenci; Roberta Spaccapelo; Carlo Toniatti; Paolo Puccetti; Francesco Bistoni; Valeria Poli
Impaired neutrophil response and CD4+ T helper cell 1 development in interleukin 6-deficient mice infected with Candida albicans.
The Journal of experimental medicine 1996;183(4):1345-55.
1995: Luigina Romani; Francesco Bistoni; Antonella Mencacci; Elio Cenci; Roberta Spaccapelo; Paolo Puccetti
IL12 in Candida albicans infections.
Research in immunology 1995;146(7-8):532-8.
1995: Roberta Spaccapelo; Luigina Romani; L Tonnetti; Elio Cenci; Antonella Mencacci; G Del Sero; R Tognellini; S G Reed; Paolo Puccetti; Francesco Bistoni
TGF-beta is important in determining the in vivo patterns of susceptibility or resistance in mice infected with Candida albicans.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(3):1349-60.
1995: L Tonnetti; Roberta Spaccapelo; Elio Cenci; Antonella Mencacci; Paolo Puccetti; R L Coffman; Francesco Bistoni; Luigina Romani
Interleukin-4 and -10 exacerbate candidiasis in mice.
European journal of immunology 1995;25(6):1559-65.
1995: Elio Cenci; Antonella Mencacci; Roberta Spaccapelo; L Tonnetti; Paolo Mosci; K H Enssle; Paolo Puccetti; Luigina Romani; Francesco Bistoni
T helper cell type 1 (Th1)- and Th2-like responses are present in mice with gastric candidiasis but protective immunity is associated with Th1 development.
The Journal of infectious diseases 1995;171(5):1279-88.
1994: Luigina Romani; Antonella Mencacci; L Tonnetti; Roberta Spaccapelo; Elio Cenci; Paolo Puccetti; Stanley Wolf; Francesco Bistoni
IL-12 is both required and prognostic in vivo for T helper type 1 differentiation in murine candidiasis.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(11):5167-75.
1994: Antonella Mencacci; A Torosantucci; Roberta Spaccapelo; Luigina Romani; Francesco Bistoni; Antonio Cassone
A mannoprotein constituent of Candida albicans that elicits different levels of delayed-type hypersensitivity, cytokine production, and anticandidal protection in mice.
Infection and immunity 1994;62(12):5353-60.
1994: Luigina Romani; Paolo Puccetti; Antonella Mencacci; Roberta Spaccapelo; Elio Cenci; L Tonnetti; Francesco Bistoni
Tolerance to staphylococcal enterotoxin B initiated Th1 cell differentiation in mice infected with Candida albicans.
Infection and immunity 1994;62(9):4047-53.
1994: Paolo Puccetti; Antonella Mencacci; Elio Cenci; Roberta Spaccapelo; Paolo Mosci; K H Enssle; Luigina Romani; Francesco Bistoni
Cure of murine candidiasis by recombinant soluble interleukin-4 receptor.
The Journal of infectious diseases 1994;169(6):1325-31.
1994: Luigina Romani; Antonella Mencacci; L Tonnetti; Roberta Spaccapelo; Elio Cenci; S Wolf; Paolo Puccetti; Francesco Bistoni
Interleukin-12 but not interferon-gamma production correlates with induction of T helper type-1 phenotype in murine candidiasis.
European journal of immunology 1994;24(4):909-15.
1994: Luigina Romani; Paolo Puccetti; Antonella Mencacci; Elio Cenci; Roberta Spaccapelo; L Tonnetti; Ursula Grohmann; Francesco Bistoni
Neutralization of IL-10 up-regulates nitric oxide production and protects susceptible mice from challenge with Candida albicans.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(7):3514-21.
1993: M Allegrucci; L Lanfaloni; C Bietta; Roberta Spaccapelo; Maria C Fioretti; Francesco Bistoni
The electrophoretic karyotype of two strains of Candida albicans by transverse alternate field electrophoresis reveals higher number of chromosomes ranging from 1 to 3.5 Mb.
Yeast (Chichester, England) 1993;9(11):1213-8.
1993: Luigina Romani; Antonella Mencacci; Elio Cenci; Roberta Spaccapelo; E Schiaffella; L Tonnetti; Paolo Puccetti; Francesco Bistoni
Natural killer cells do not play a dominant role in CD4+ subset differentiation in Candida albicans-infected mice.
Infection and immunity 1993;61(9):3769-74.
1993: Elio Cenci; Luigina Romani; Antonella Mencacci; Roberta Spaccapelo; E Schiaffella; Paolo Puccetti; Francesco Bistoni
Interleukin-4 and interleukin-10 inhibit nitric oxide-dependent macrophage killing of Candida albicans.
European journal of immunology 1993;23(5):1034-8.
1993: Luigina Romani; Antonella Mencacci; Elio Cenci; Roberta Spaccapelo; Paolo Mosci; Paolo Puccetti; Francesco Bistoni
CD4+ subset expression in murine candidiasis. Th responses correlate directly with genetically determined susceptibility or vaccine-induced resistance.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(3):925-31.
1992: Luigina Romani; Elio Cenci; Antonella Mencacci; Roberta Spaccapelo; Ursula Grohmann; Paolo Puccetti; Francesco Bistoni
Gamma interferon modifies CD4+ subset expression in murine candidiasis.
Infection and immunity 1992;60(11):4950-2.