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Christian Spangenberg

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Chemicals & Drugs

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Publications

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Jan G Hengstler; Ernesto Bockamp; Matthias Hermes; Marc Brulport; Alexander Bauer; Wiebke Schormann; Ilka B Schiffer; C Hausherr; Leonid Eshkind; Cecilia Antunes; A Franzen; Krishnamurthi Kannan; Ekkehart U Lausch; Rüdiger Lessig; Tapan Chakrabarti; Dirk Prawitt; Bernhard Zabel; Christian Spangenberg
Oncogene-blocking therapies: new insights from conditional mouse tumor models.
Carolin K Hausherr; Ilka B Schiffer; Susanne Gebhard; Andreas Banić; Berno Tanner; Heinz Kolbl; Eric Thoenes; Thomas Beckers; Christian Spangenberg; Dirk Prawitt; Tatjana M Trost; Bernhard Zabel; Franz Oesch; Matthias Hermes; Jan G Hengstler
Dephosphorylation of p-ERK1/2 in relation to tumor remission after HER-2 and Raf1 blocking therapy in a conditional mouse tumor model.
Christian Spangenberg; Ekkehart U Lausch; Tatjana M Trost; Dirk Prawitt; Andreas May; Romy Keppler; Stephan Fees; Dirk Reutzel; Carolin Bell; Steffen Schmitt; Ilka B Schiffer; Achim Weber; Walburgis Brenner; Matthias Hermes; Ugur Sahin; Ozlem Türeci; Heinz Koelbl; Jan G Hengstler; Bernhard Zabel
ERBB2-mediated transcriptional up-regulation of the alpha5beta1 integrin fibronectin receptor promotes tumor cell survival under adverse conditions.

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All Publications

2006: Jan G Hengstler; Ernesto Bockamp; Matthias Hermes; Marc Brulport; Alexander Bauer; Wiebke Schormann; Ilka B Schiffer; C Hausherr; Leonid Eshkind; Cecilia Antunes; A Franzen; Krishnamurthi Kannan; Ekkehart U Lausch; Rüdiger Lessig; Tapan Chakrabarti; Dirk Prawitt; Bernhard Zabel; Christian Spangenberg
Oncogene-blocking therapies: new insights from conditional mouse tumor models.
Current cancer drug targets 2006;6(7):603-12.
2006: Carolin K Hausherr; Ilka B Schiffer; Susanne Gebhard; Andreas Banić; Berno Tanner; Heinz Kolbl; Eric Thoenes; Thomas Beckers; Christian Spangenberg; Dirk Prawitt; Tatjana M Trost; Bernhard Zabel; Franz Oesch; Matthias Hermes; Jan G Hengstler
Dephosphorylation of p-ERK1/2 in relation to tumor remission after HER-2 and Raf1 blocking therapy in a conditional mouse tumor model.
Molecular carcinogenesis 2006;45(5):302-8.
2006: Christian Spangenberg; Ekkehart U Lausch; Tatjana M Trost; Dirk Prawitt; Andreas May; Romy Keppler; Stephan Fees; Dirk Reutzel; Carolin Bell; Steffen Schmitt; Ilka B Schiffer; Achim Weber; Walburgis Brenner; Matthias Hermes; Ugur Sahin; Ozlem Türeci; Heinz Koelbl; Jan G Hengstler; Bernhard Zabel
ERBB2-mediated transcriptional up-regulation of the alpha5beta1 integrin fibronectin receptor promotes tumor cell survival under adverse conditions.
Cancer research 2006;66(7):3715-25.
2005: Dirk Prawitt; Thorsten Enklaar; Barbara Gärtner-Rupprecht; Christian Spangenberg; Ekkehart U Lausch; Dirk Reutzel; Stephan Fees; Maria Korzon; Izabela Brozek; Janusz Limon; David E Housman; Jerry Pelletier; Bernhard Zabel
Microdeletion and IGF2 loss of imprinting in a cascade causing Beckwith-Wiedemann syndrome with Wilms' tumor.
Nature genetics 2005;37(8):785-6; author reply 786-7.
2005: Dirk Prawitt; Thorsten Enklaar; Barbara Gärtner-Rupprecht; Christian Spangenberg; Monika Oswald; Ekkehart U Lausch; Peter Schmidtke; Dirk Reutzel; Stephan Fees; Rob Lucito; Maria Korzon; Izabela Brozek; Janusz Limon; David E Housman; Jerry Pelletier; Bernhard Zabel
Microdeletion of target sites for insulator protein CTCF in a chromosome 11p15 imprinting center in Beckwith-Wiedemann syndrome and Wilms' tumor.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(11):4085-90.
2005: Tatjana M Trost; Ekkehart U Lausch; Stephan Fees; Steffen Schmitt; Thorsten Enklaar; Dirk Reutzel; Lili R Brixel; Peter Schmidtke; Marko Maringer; Ilka B Schiffer; Carolin K Heimerdinger; Jan G Hengstler; Gerhard Fritz; Ernesto Bockamp; Dirk Prawitt; Bernhard Zabel; Christian Spangenberg
Premature senescence is a primary fail-safe mechanism of ERBB2-driven tumorigenesis in breast carcinoma cells.
Cancer research 2005;65(3):840-9.
2004: Kurt Eger; Matthias Hermes; K Uhlemann; S Rodewald; J Ortwein; Marc Brulport; A W Bauer; Wiebke Schormann; F Lupatsch; Ilka B Schiffer; Carolin K Heimerdinger; Susanne Gebhard; Christian Spangenberg; Dirk Prawitt; Tatjana M Trost; Bernhard Zabel; C Sauer; B Tanner; Heinz Kolbl; Ute Krügel; Heike Franke; Peter Illes; Petra Madaj-Sterba; Ernesto Bockamp; Thomas Beckers; Jan G Hengstler
4-Epidoxycycline: an alternative to doxycycline to control gene expression in conditional mouse models.
Biochemical and biophysical research communications 2004;323(3):979-86.
2004: Dirk Prawitt; Lili R Brixel; Christian Spangenberg; Leonid Eshkind; Rosario Heck; Franz Oesch; Bernhard Zabel; Ernesto Bockamp
RNAi knock-down mice: an emerging technology for post-genomic functional genetics.
Cytogenetic and genome research 2004;105(2-4):412-21.
2003: Dirk Prawitt; Mahealani K Monteilh-Zoller; Lili R Brixel; Christian Spangenberg; Bernhard Zabel; Andrea Fleig; Reinhold Penner
TRPM5 is a transient Ca2+-activated cation channel responding to rapid changes in [Ca2+]i.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(25):15166-71.
2003: Ilka B Schiffer; Susanne Gebhard; Carolin K Heimerdinger; Annette Heling; Jochem Hast; Ursula Wollscheid; Barbara Seliger; Berno Tanner; Sandra Gilbert; Thomas Beckers; Silke Baasner; Walburgis Brenner; Christian Spangenberg; Dirk Prawitt; Tatjana M Trost; Wolfgang G Schreiber; Bernhard Zabel; Manfred Thelen; Hans-Anton Lehr; Franz Oesch; Jan G Hengstler
Switching off HER-2/neu in a tetracycline-controlled mouse tumor model leads to apoptosis and tumor-size-dependent remission.
Cancer research 2003;63(21):7221-31.
2002: Ernesto Bockamp; Marko Maringer; Christian Spangenberg; Stephan Fees; Stuart Fraser; Leonid Eshkind; Franz Oesch; Bernhard Zabel
Of mice and models: improved animal models for biomedical research.
Physiological genomics 2002;11(3):115-32.
2000: Dirk Prawitt; Thorsten Enklaar; G Klemm; B Gärtner; Christian Spangenberg; Andreas Winterpacht; Michael J Higgins; Jerry Pelletier; Bernhard Zabel
Identification and characterization of MTR1, a novel gene with homology to melastatin (MLSN1) and the trp gene family located in the BWS-WT2 critical region on chromosome 11p15.5 and showing allele-specific expression.
Human molecular genetics 2000;9(2):203-16.
1999: Patrick Gerner; Ekkehart U Lausch; Michael Friedt; R Tratzmüller; Christian Spangenberg; Stefan Wirth
Hepatitis B virus core promoter mutations in children with multiple anti-HBe/HBeAg reactivations result in enhanced promoter activity.
Journal of medical virology 1999;59(4):415-23.
1998: Christian Spangenberg; Andreas Winterpacht; Bernhard Zabel; R W Löbbert
Cloning and characterization of a novel gene (TM7SF1) encoding a putative seven-pass transmembrane protein that is upregulated during kidney development.
Genomics 1998;48(2):178-85.