FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Carl Sparrow

Research Profile

Living Beings

Chemicals & Drugs

Concepts & Ideas

Genes & Molecular Sequences

Molecular Structure

Anatomy

Disorders

Arteriosclerosis

Co-author Network

Publications

TOP 3
Alison M Strack; Anil Thankappan; Xinchun Tong; Sheng-Ping Wang; M Gerard Waters; Michael Wolff; John Woods; T J Wu; Jiyan Xue; Emanuel Zycband; Charlotte Burton; Ester Carballo-Jane; Ching H Chang; Jing Chen; Brian Hubbard; Douglas Kawka; Silvi Luell; Michele Mariano; Lesley Ann McNamara; John Menke; Gary O'Neill; Xiaoli Ping; Olga Price; Richard Raubertas; Carl P Sparrow; Ayesha Sitlani
Nicotinic acid and DP1 blockade: studies in mouse models of atherosclerosis.
Zhu Chen; Suzanne Eveland; Timothy S Fisher; Betsy Frantz-Wattley; Karen Gagen; Brian K Hubbard; Marina Ichetovkin; Douglas G Johns; Silvi Luell; Roger Meurer; Edward A O'Neill; Carl P Sparrow; Alison M Strack; Sheng-Ping Wang; Samuel D Wright; Ester Carballo-Jane
Reconstituted HDL elicits marked changes in plasma lipids following single-dose injection in C57Bl/6 mice.
Anita Y H Lee; James Loderstedt; John S Millar; Daniel J Rader; Ayesha Sitlani; Katie Southwick; Carl P Sparrow; Nykia Walker; Weixun Wang; Nathan A Yates; Xuemei Zhao; Haihong Zhou; Ekaterina Deyanova; Timothy S Fisher; Brian K Hubbard; Marina Ichetovkin; Ronald C Hendrickson
Measurement of fractional synthetic rates of multiple protein analytes by triple quadrupole mass spectrometry.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Carl Sparrow (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Alison M Strack; Anil Thankappan; Xinchun Tong; Sheng-Ping Wang; M Gerard Waters; Michael Wolff; John Woods; T J Wu; Jiyan Xue; Emanuel Zycband; Charlotte Burton; Ester Carballo-Jane; Ching H Chang; Jing Chen; Brian Hubbard; Douglas Kawka; Silvi Luell; Michele Mariano; Lesley Ann McNamara; John Menke; Gary O'Neill; Xiaoli Ping; Olga Price; Richard Raubertas; Carl P Sparrow; Ayesha Sitlani
Nicotinic acid and DP1 blockade: studies in mouse models of atherosclerosis.
Journal of lipid research 2013;54(1):177-88.
2012: Zhu Chen; Suzanne Eveland; Timothy S Fisher; Betsy Frantz-Wattley; Karen Gagen; Brian K Hubbard; Marina Ichetovkin; Douglas G Johns; Silvi Luell; Roger Meurer; Edward A O'Neill; Carl P Sparrow; Alison M Strack; Sheng-Ping Wang; Samuel D Wright; Ester Carballo-Jane
Reconstituted HDL elicits marked changes in plasma lipids following single-dose injection in C57Bl/6 mice.
Journal of cardiovascular pharmacology and therapeutics 2012;17(3):315-23.
2012: Anita Y H Lee; James Loderstedt; John S Millar; Daniel J Rader; Ayesha Sitlani; Katie Southwick; Carl P Sparrow; Nykia Walker; Weixun Wang; Nathan A Yates; Xuemei Zhao; Haihong Zhou; Ekaterina Deyanova; Timothy S Fisher; Brian K Hubbard; Marina Ichetovkin; Ronald C Hendrickson
Measurement of fractional synthetic rates of multiple protein analytes by triple quadrupole mass spectrometry.
Clinical chemistry 2012;58(3):619-27.
2011: Cameron J Smith; Carl P Sparrow; Gayle E Taylor; Christopher F Thompson; Xinchun Tong; Samuel D Wright; Suoyu S Xu; Amjad Ali; Matt S Anderson; Y Chen; Anne Marie Cumiskey; Suzanne S Eveland; Qiu Guo; Milton L Hammond; Sheryl A Hyland; Melanie Latham; Hong Li; Zhijian Lu; Denise P Milot; Joann Napolitano; Laurence B Peterson; James V Pivnichny; R Rosa; Peter J Sinclair
Biphenyl-substituted oxazolidinones as cholesteryl ester transfer protein inhibitors: modifications of the oxazolidinone ring leading to the discovery of anacetrapib.
Journal of medicinal chemistry 2011;54(13):4880-95.
2011: Ramzi F Sweis; Julianne A Hunt; Peter J Sinclair; Y Chen; Suzanne S Eveland; Qiu Guo; Sheryl A Hyland; Denise P Milot; Anne Marie Cumiskey; Melanie Latham; R Rosa; Larry Peterson; Carl P Sparrow; Matt S Anderson
2-(4-Carbonylphenyl)benzoxazole inhibitors of CETP: attenuation of hERG binding and improved HDLc-raising efficacy.
Bioorganic & medicinal chemistry letters 2011;21(9):2597-600.
2011: Ramzi F Sweis; Julianne A Hunt; Florida Kallashi; Milton L Hammond; Y Chen; Suzanne S Eveland; Qiu Guo; Sheryl A Hyland; Denise P Milot; Anne-Marie Cumiskey; Melanie Latham; R Rosa; Larry Peterson; Carl P Sparrow; Samuel D Wright; Matt S Anderson; Peter J Sinclair
2-(4-carbonylphenyl)benzoxazole inhibitors of CETP: scaffold design and advancement in HDLc-raising efficacy.
Bioorganic & medicinal chemistry letters 2011;21(6):1890-5.
2011: Florida Kallashi; Dooseop Kim; Jennifer Kowalchick; You Jung Park; Julianne A Hunt; Amjad Ali; Cameron J Smith; Milton L Hammond; James V Pivnichny; Xinchun Tong; Suoyu S Xu; Matt S Anderson; Y Chen; Suzanne S Eveland; Qiu Guo; Sheryl A Hyland; Denise P Milot; Anne Marie Cumiskey; Melanie Latham; Laurence B Peterson; R Rosa; Carl P Sparrow; Samuel D Wright; Peter J Sinclair
2-Arylbenzoxazoles as CETP inhibitors: raising HDL-C in cynoCETP transgenic mice.
Bioorganic & medicinal chemistry letters 2011;21(1):558-61.
2011: Yan G Ni; Stefania Di Marco; Jon H Condra; Laurence B Peterson; Weirong Wang; Fubao Wang; Shilpa Pandit; Holly A Hammond; Ray Rosa; Richard T Cummings; Dana D Wood; Xiaomei Liu; Matthew J Bottomley; Xun Shen; Rose M Cubbon; Sheng-ping Wang; Douglas G Johns; Cinzia Volpari; Lora Hamuro; Jayne Chin; Lingyi Huang; Jing Zhang Zhao; Salvatore Vitelli; Peter Haytko; Douglas Wisniewski; Lyndon J Mitnaul; Carl P Sparrow; Brian Hubbard; Andrea Carfí; Ayesha Sitlani
A PCSK9-binding antibody that structurally mimics the EGF(A) domain of LDL-receptor reduces LDL cholesterol in vivo.
Journal of lipid research 2011;52(1):78-86.
2010: Mollie Ranalletta; Kathleen K Bierilo; Y Chen; Denise P Milot; Qing Chen; Elaine Tung; Caroline Houde; Nadine H Elowe; Margarita Garcia-Calvo; Gene Porter; Suzanne Eveland; Betsy Frantz-Wattley; Michael Kavana; George Addona; Peter Sinclair; Carl P Sparrow; Edward A O'Neill; Ken S Koblan; Ayesha Sitlani; Brian Hubbard; Timothy S Fisher
Biochemical characterization of cholesteryl ester transfer protein inhibitors.
Journal of lipid research 2010;51(9):2739-52.
2010: Julianne A Hunt; Silvia Gonzalez; Florida Kallashi; Milton L Hammond; James V Pivnichny; Xinchun Tong; Suoyu S Xu; Matt S Anderson; Y Chen; Suzanne S Eveland; Qiu Guo; Sheryl A Hyland; Denise P Milot; Carl P Sparrow; Samuel D Wright; Peter J Sinclair
2-Arylbenzoxazoles as CETP inhibitors: substitution and modification of the alpha-alkoxyamide moiety.
Bioorganic & medicinal chemistry letters 2010;20(3):1019-22.
2010: Cameron J Smith; Amjad Ali; Liya Chen; Milton L Hammond; Matt S Anderson; Y Chen; Suzanne S Eveland; Qiu Guo; Sheryl A Hyland; Denise P Milot; Carl P Sparrow; Samuel D Wright; Peter J Sinclair
2-Arylbenzoxazoles as CETP inhibitors: Substitution of the benzoxazole moiety.
Bioorganic & medicinal chemistry letters 2010;20(1):346-9.
2008: Michael J Forrest; D Bloomfield; R J Briscoe; P N Brown; Anne Marie Cumiskey; J Ehrhart; J C Hershey; W J Keller; X Ma; H E McPherson; E Messina; Laurence B Peterson; W Sharif-Rodriguez; P K S Siegl; Peter J Sinclair; Carl P Sparrow; A S Stevenson; S-Y Sun; C Tsai; H Vargas; M Walker; S H West; V White; RF Woltmann
Torcetrapib-induced blood pressure elevation is independent of CETP inhibition and is accompanied by increased circulating levels of aldosterone.
British journal of pharmacology 2008;154(7):1465-73.
2008: Shilpa Pandit; Doug Wisniewski; Joseph C Santoro; Sookhee Ha; Vijayalakshmi Ramakrishnan; Rose M Cubbon; Richard T Cummings; Samuel D Wright; Carl P Sparrow; Ayesha Sitlani; Timothy S Fisher
Functional analysis of sites within PCSK9 responsible for hypercholesterolemia.
Journal of lipid research 2008;49(6):1333-43.
2008: Stephen M Soisson; Gopalakrishnan Parthasarathy; Alan D Adams; Soumya Sahoo; Ayesha Sitlani; Carl P Sparrow; Jisong Cui; Joseph W Becker
Identification of a potent synthetic FXR agonist with an unexpected mode of binding and activation.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(14):5337-42.
2007: Suzanne S Eveland; Denise P Milot; Qiu Guo; Ying Chen; Sheryl A Hyland; Laurence B Peterson; Sylvie Jezequel-Sur; Gregory T O'Donnell; Paul Zuck; Marc Ferrer; Berta Strulovici; John A Wagner; Wesley K Tanaka; Deborah Hilliard; Omar Laterza; Samuel D Wright; Carl P Sparrow; Matt S Anderson
A high-precision fluorogenic cholesteryl ester transfer protein assay compatible with animal serum and 3456-well assay technology.
Analytical biochemistry 2007;368(2):239-49.
2007: Timothy S Fisher; Paola Lo Surdo; Shilpa Pandit; Marco Mattu; Joseph C Santoro; Doug Wisniewski; Richard T Cummings; Alessandra Calzetta; Rose M Cubbon; Paul A Fischer; Anil Tarachandani; Raffaele De Francesco; Samuel D Wright; Carl P Sparrow; Andrea Carfi; Ayesha Sitlani
Effects of pH and low density lipoprotein (LDL) on PCSK9-dependent LDL receptor regulation.
The Journal of biological chemistry 2007;282(28):20502-12.
2007: Lyndon J Mitnaul; Jenny Tian; Charlotte Burton; My-Hanh Lam; Yuping Zhu; Steve H Olson; Jonathan E Schneeweis; Paul Zuck; Shilpa Pandit; Matt Anderson; Milana M Maletic; Sherman T Waddell; Samuel D Wright; Carl P Sparrow; Erik G Lund
Fluorogenic substrates for high-throughput measurements of endothelial lipase activity.
Journal of lipid research 2007;48(2):472-82.
2006: Jason W Szewczyk; Shaei Huang; Jayne Chin; Jenny Tian; Lyndon Mitnaul; Raymond L Rosa; Larry Peterson; Carl P Sparrow; Alan D Adams
SAR studies: designing potent and selective LXR agonists.
Bioorganic & medicinal chemistry letters 2006;16(11):3055-60.
2006: Erik G Lund; Laurence B Peterson; Alan D Adams; My-Hanh Lam; Charlotte A Burton; Jayne Chin; Qiu Guo; Shaei Huang; Melanie Latham; Jacqueline C Lopez; John G Menke; Denise P Milot; Lyndon J Mitnaul; Sandra E Rex-Rabe; Raymond L Rosa; Jenny Y Tian; Samuel D Wright; Carl P Sparrow
Different roles of liver X receptor alpha and beta in lipid metabolism: effects of an alpha-selective and a dual agonist in mice deficient in each subtype.
Biochemical pharmacology 2006;71(4):453-63.
2005: Weiguo Liu; Steve Chen; James F Dropinski; Lawrence Colwell; Michael Robins; Michael Szymonifka; Nancy Hayes; Neelam Sharma; Karen L Macnaul; Melba Hernandez; Charlotte Burton; Carl P Sparrow; John G Menke; Sheo B Singh
Design, synthesis, and structure-activity relationship of podocarpic acid amides as liver X receptor agonists for potential treatment of atherosclerosis.
Bioorganic & medicinal chemistry letters 2005;15(20):4574-8.
2005: Sheo B Singh; John G Ondeyka; Weiguo Liu; Steve Chen; Tom S Chen; Xiaohua Li; Aileen Bouffard; James F Dropinski; A Brian Jones; Sherrie McCormick; Nancy Hayes; Jianhua Wang; Neelam Sharma; Karen L Macnaul; Melba Hernandez; Yu-Sheng Chao; Joanne Baffic; My-Hanh Lam; Charlotte Burton; Carl P Sparrow; John G Menke
Discovery and development of dimeric podocarpic acid leads as potent agonists of liver X receptor with HDL cholesterol raising activity in mice and hamsters.
Bioorganic & medicinal chemistry letters 2005;15(11):2824-8.
2004: Qiu Guo; Soumya P Sahoo; Pei-ran Wang; Denise P Milot; Marc C Ippolito; Margaret S Wu; Joanne Baffic; Chhabi Biswas; Melba Hernandez; My-Hanh Lam; Neelam Sharma; Wei Han; Linda J Kelly; Karen L Macnaul; Gaochao Zhou; Ranjit Desai; James V Heck; Thomas W Doebber; Joel P Berger; David E Moller; Carl P Sparrow; Yu-Sheng Chao; Samuel D Wright
A novel peroxisome proliferator-activated receptor alpha/gamma dual agonist demonstrates favorable effects on lipid homeostasis.
Endocrinology 2004;145(4):1640-8.
2003: Jayne Chin; Alan D Adams; Aileen Bouffard; Ahren Green; Raul Lacson; Todd Smith; Paul A Fischer; John G Menke; Carl P Sparrow; Lyndon J Mitnaul
Miniaturization of cell-based beta-lactamase-dependent FRET assays to ultra-high throughput formats to identify agonists of human liver X receptors.
Assay and drug development technologies 2003;1(6):777-87.
2003: Erik G Lund; John G Menke; Carl P Sparrow
Liver X receptor agonists as potential therapeutic agents for dyslipidemia and atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(7):1169-77.
2002: John G Menke; Karen L Macnaul; Nancy S Hayes; Joanne Baffic; Yu-Sheng Chao; Alex Elbrecht; Linda J Kelly; My-Hanh Lam; Azriel Schmidt; Soumya Sahoo; Jianhua Wang; Samuel D Wright; Patrick Xin; Gaochao Zhou; David E Moller; Carl P Sparrow
A novel liver X receptor agonist establishes species differences in the regulation of cholesterol 7alpha-hydroxylase (CYP7a).
Endocrinology 2002;143(7):2548-58.
2002: Charlotte A Burton; Sushma Patel; Steven S Mundt; Heide Hassing; Donghui Zhang; Anne Hermanowski-Vosatka; Samuel D Wright; Yu-Sheng Chao; Patricia A Detmers; Carl P Sparrow
Deficiency in sPLA(2) does not affect HDL levels or atherosclerosis in mice.
Biochemical and biophysical research communications 2002;294(1):88-94.
2002: Carl P Sparrow; Joanne Baffic; My-Hanh Lam; Erik G Lund; Alan D Adams; Xuan Fu; Nancy Hayes; A Brian Jones; Karen L Macnaul; John G Ondeyka; Sheo Singh; Jianhua Wang; Gaochao Zhou; David E Moller; Samuel D Wright; John G Menke
A potent synthetic LXR agonist is more effective than cholesterol loading at inducing ABCA1 mRNA and stimulating cholesterol efflux.
The Journal of biological chemistry 2002;277(12):10021-7.
2001: Xiaodong Gan; Rebecca Kaplan; John G Menke; Karen L Macnaul; Y Chen; Carl P Sparrow; Gaochao Zhou; Samuel D Wright; Tian-Quan Cai
Dual mechanisms of ABCA1 regulation by geranylgeranyl pyrophosphate.
The Journal of biological chemistry 2001;276(52):48702-8.
2001: X Fu; John G Menke; Y Chen; Gaochao Zhou; Karen L Macnaul; Samuel D Wright; Carl P Sparrow; Erik G Lund
27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells.
The Journal of biological chemistry 2001;276(42):38378-87.
2001: Carl P Sparrow; Charlotte A Burton; Melba Hernandez; Steven S Mundt; Heide Hassing; S Patel; R Rosa; Anne Hermanowski-Vosatka; Pei-ran Wang; D Zhang; L Peterson; Patricia A Detmers; Yu-Sheng Chao; Samuel D Wright
Simvastatin has anti-inflammatory and antiatherosclerotic activities independent of plasma cholesterol lowering.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(1):115-21.
2000: Patricia A Detmers; Melba Hernandez; John S Mudgett; Heide Hassing; Charlotte Burton; Steven S Mundt; S Chun; D Fletcher; Deborah Card; JeanMarie Lisnock; R Weikel; James Bergstrom; D E Shevell; Anne Hermanowski-Vosatka; Carl P Sparrow; Yu-Sheng Chao; D J Rader; Samuel D Wright; Ellen Puré
Deficiency in inducible nitric oxide synthase results in reduced atherosclerosis in apolipoprotein E-deficient mice.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(6):3430-5.
2000: Patricia A Detmers; Sushma Patel; Melba Hernandez; J Montenegro; JeanMarie Lisnock; Bill Pikounis; M Steiner; D Kim; Carl P Sparrow; Yu-Sheng Chao; Samuel D Wright
A target for cholesterol absorption inhibitors in the enterocyte brush border membrane.
Biochimica et biophysica acta 2000;1486(2-3):243-52.
2000: Melba Hernandez; J Montenegro; M Steiner; D Kim; Carl P Sparrow; Patricia A Detmers; Samuel D Wright; Yu-Sheng Chao
Intestinal absorption of cholesterol is mediated by a saturable, inhibitable transporter.
Biochimica et biophysica acta 2000;1486(2-3):232-42.
2000: Mark D Leibowitz; Catherine Fiévet; Nathalie Hennuyer; Julia Peinado-Onsurbe; Hélène Duez; J Bergera; C A Cullinan; Carl P Sparrow; Joanne Baffic; G D Berger; C Santini; R W Marquis; Richard L Tolman; Roy G Smith; David E Moller; Johan Auwerx
Activation of PPARdelta alters lipid metabolism in db/db mice.
FEBS letters 2000;473(3):333-6.
2000: Samuel D Wright; C Burton; Melba Hernandez; Heide Hassing; J Montenegro; Steven S Mundt; S Patel; Deborah Card; Anne Hermanowski-Vosatka; James Bergstrom; Carl P Sparrow; Patricia A Detmers; Yu-Sheng Chao
Infectious agents are not necessary for murine atherogenesis.
The Journal of experimental medicine 2000;191(8):1437-42.
1999: Carl P Sparrow; Sushma Patel; Joanne Baffic; Yu-Sheng Chao; Melba Hernandez; My-Hanh Lam; J Montenegro; Samuel D Wright; Patricia A Detmers
A fluorescent cholesterol analog traces cholesterol absorption in hamsters and is esterified in vivo and in vitro.
Journal of lipid research 1999;40(10):1747-57.
1998: X Xing; Joanne Baffic; Carl P Sparrow
LDL oxidation by activated monocytes: characterization of the oxidized LDL and requirement for transition metal ions.
Journal of lipid research 1998;39(11):2201-8.
1993: Carl P Sparrow; J Olszewski
Cellular oxidation of low density lipoprotein is caused by thiol production in media containing transition metal ions.
Journal of lipid research 1993;34(7):1219-28.
1992: Carl P Sparrow; Thomas W Doebber; J Olszewski; M S Wu; John Ventre; K A Stevens; Y S Chao
Low density lipoprotein is protected from oxidation and the progression of atherosclerosis is slowed in cholesterol-fed rabbits by the antioxidant N,N'-diphenyl-phenylenediamine.
The Journal of clinical investigation 1992;89(6):1885-91.
1992: Carl P Sparrow; J Olszewski
Cellular oxidative modification of low density lipoprotein does not require lipoxygenases.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(1):128-31.