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Maria Spassova

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Maria A Spassova; Thamara Hewavitharana; Richard A Fandino; Asli Kaya; Jacqueline Tanaka; Donald L Gill
Voltage gating at the selectivity filter of the Ca2+ release-activated Ca2+ channel induced by mutation of the Orai1 protein.
Jonathan Soboloff; Maria A Spassova; Thamara Hewavitharana; Li-Ping He; Paz Luncsford; Wen Xu; Kartik Venkatachalam; Damian B van Rossum; Randen L Patterson; Donald L Gill
TRPC channels: integrators of multiple cellular signals.
Jonathan Soboloff; Maria A Spassova; Marie A Dziadek; Donald L Gill
Calcium signals mediated by STIM and Orai proteins--a new paradigm in inter-organelle communication.

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All Publications

2008: Maria A Spassova; Thamara Hewavitharana; Richard A Fandino; Asli Kaya; Jacqueline Tanaka; Donald L Gill
Voltage gating at the selectivity filter of the Ca2+ release-activated Ca2+ channel induced by mutation of the Orai1 protein.
The Journal of biological chemistry 2008;283(22):14938-45.
2007: Jonathan Soboloff; Maria A Spassova; Thamara Hewavitharana; Li-Ping He; Paz Luncsford; Wen Xu; Kartik Venkatachalam; Damian B van Rossum; Randen L Patterson; Donald L Gill
TRPC channels: integrators of multiple cellular signals.
Handbook of experimental pharmacology 2007;(179):575-91.
2006: Jonathan Soboloff; Maria A Spassova; Marie A Dziadek; Donald L Gill
Calcium signals mediated by STIM and Orai proteins--a new paradigm in inter-organelle communication.
Biochimica et biophysica acta 2006;1763(11):1161-8.
2006: Maria A Spassova; Thamara Hewavitharana; Wen Xu; Jonathan Soboloff; Donald L Gill
A common mechanism underlies stretch activation and receptor activation of TRPC6 channels.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(44):16586-91.
2006: Jonathan Soboloff; Maria A Spassova; Xiang D Tang; Thamara Hewavitharana; Wen Xu; Donald L Gill
Orai1 and STIM reconstitute store-operated calcium channel function.
The Journal of biological chemistry 2006;281(30):20661-5.
2006: Jonathan Soboloff; Maria A Spassova; Thamara Hewavitharana; Li-Ping He; Wen Xu; Lorna S Johnstone; Marie A Dziadek; Donald L Gill
STIM2 is an inhibitor of STIM1-mediated store-operated Ca2+ Entry.
Current biology : CB 2006;16(14):1465-70.
2006: Donald L Gill; Maria A Spassova; Jonathan Soboloff
Signal transduction. Calcium entry signals--trickles and torrents.
Science (New York, N.Y.) 2006;313(5784):183-4.
2006: Maria A Spassova; Jonathan Soboloff; Li-Ping He; Wen Xu; Marie A Dziadek; Donald L Gill
STIM1 has a plasma membrane role in the activation of store-operated Ca(2+) channels.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(11):4040-5.
2005: Jonathan Soboloff; Maria A Spassova; Wen Xu; Li-Ping He; Natalia Cuesta; Donald L Gill
Role of endogenous TRPC6 channels in Ca2+ signal generation in A7r5 smooth muscle cells.
The Journal of biological chemistry 2005;280(48):39786-94.
2005: Susan F Slovin; Govind Ragupathi; Celina Fernandez; Matthew P Jefferson; Meghan Diani; Andrew Wilton; Shemeeakah Powell; Maria A Spassova; Celso Reis; Henrik Clausen; Samuel J Danishefsky; Philip O Livingston; Howard I Scher
A bivalent conjugate vaccine in the treatment of biochemically relapsed prostate cancer: a study of glycosylated MUC-2-KLH and Globo H-KLH conjugate vaccines given with the new semi-synthetic saponin immunological adjuvant GPI-0100 OR QS-21.
Vaccine 2005;23(24):3114-22.
2005: Li-Ping He; Thamara Hewavitharana; Jonathan Soboloff; Maria A Spassova; Donald L Gill
A functional link between store-operated and TRPC channels revealed by the 3,5-bis(trifluoromethyl)pyrazole derivative, BTP2.
The Journal of biological chemistry 2005;280(12):10997-1006.
2004: Maria A Spassova; Jonathan Soboloff; Li-Ping He; Thamara Hewavitharana; Wen Xu; Kartik Venkatachalam; Damian B van Rossum; Randen L Patterson; Donald L Gill
Calcium entry mediated by SOCs and TRP channels: variations and enigma.
Biochimica et biophysica acta 2004;1742(1-3):9-20.
2004: Maria A Spassova; Michael Avissar; Adam C Furman; Mark A Crumling; James C Saunders; Thomas D Parsons
Evidence that rapid vesicle replenishment of the synaptic ribbon mediates recovery from short-term adaptation at the hair cell afferent synapse.
Journal of the Association for Research in Otolaryngology : JARO 2004;5(4):376-90.
2004: Marc D Eisen; Maria A Spassova; Thomas D Parsons
Large releasable pool of synaptic vesicles in chick cochlear hair cells.
Journal of neurophysiology 2004;91(6):2422-8.
2003: Govind Ragupathi; Fusataka Koide; Natarajan Sathyan; Ella Kagan; Maria A Spassova; William G Bornmann; Polly D Gregor; Celso A Reis; Henrik Clausen; Samuel J Danishefsky; Philip O Livingston
A preclinical study comparing approaches for augmenting the immunogenicity of a heptavalent KLH-conjugate vaccine against epithelial cancers.
Cancer immunology, immunotherapy : CII 2003;52(10):608-16.
2002: Govind Ragupathi; Sarah Cappello; San San Yi; Dan Canter; Maria A Spassova; William G Bornmann; Samuel J Danishefsky; Philip O Livingston
Comparison of antibody titers after immunization with monovalent or tetravalent KLH conjugate vaccines.
Vaccine 2002;20(7-8):1030-8.
2001: Maria A Spassova; Marc D Eisen; James C Saunders; Thomas D Parsons
Chick cochlear hair cell exocytosis mediated by dihydropyridine-sensitive calcium channels.
The Journal of physiology 2001;535(Pt 3):689-96.
2001: Shawn J Stachel; Chul Bom Lee; Maria A Spassova; Mark D Chappell; William G Bornmann; Samuel J Danishefsky; Ting-Chao Chou; Yongbiao Guan
On the interactivity of complex synthesis and tumor pharmacology in the drug discovery process: total synthesis and comparative in vivo evaluations of the 15-aza epothilones.
The Journal of organic chemistry 2001;66(12):4369-78.
2001: Teresa A Gilewski; Govind Ragupathi; S Bhuta; Linda J Williams; Cristina Musselli; XF Zhang; William G Bornmann; Maria A Spassova; K P Bencsath; Katherine S Panageas; J Chin; Clifford Hudis; Larry Norton; Alan N Houghton; Philip O Livingston; Samuel J Danishefsky
Immunization of metastatic breast cancer patients with a fully synthetic globo H conjugate: a phase I trial.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(6):3270-5.
2000: Paul Sabbatini; V Kudryashov; Govind Ragupathi; Samuel J Danishefsky; Philip O Livingston; William G Bornmann; Maria A Spassova; A Zatorski; David Spriggs; Carol Aghajanian; Steven L Soignet; M Peyton; Catherine O'Flaherty; J Curtin; Kenneth O Lloyd
Immunization of ovarian cancer patients with a synthetic Lewis(y)-protein conjugate vaccine: a phase 1 trial.
International journal of cancer. Journal international du cancer 2000;87(1):79-85.
2000: ZG Wang; Linda J Williams; XF Zhang; A Zatorski; V Kudryashov; Govind Ragupathi; Maria A Spassova; William G Bornmann; Susan F Slovin; Howard I Scher; Philip O Livingston; Kenneth O Lloyd; Samuel J Danishefsky
Polyclonal antibodies from patients immunized with a globo H-keyhole limpet hemocyanin vaccine: isolation, quantification, and characterization of immune responses by using totally synthetic immobilized tumor antigens.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(6):2719-24.
1999: Maria A Spassova; Zhe Lu
Tuning the voltage dependence of tetraethylammonium block with permeant ions in an inward-rectifier K+ channel.
The Journal of general physiology 1999;114(3):415-26.
1999: Susan F Slovin; Govind Ragupathi; S Adluri; G Ungers; K Terry; S Kim; Maria A Spassova; William G Bornmann; Melissa Fazzari; L Dantis; Krystyna M Olkiewicz; Kenneth O Lloyd; Philip O Livingston; Samuel J Danishefsky; Howard I Scher
Carbohydrate vaccines in cancer: immunogenicity of a fully synthetic globo H hexasaccharide conjugate in man.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(10):5710-5.
1998: Maria A Spassova; Zhe Lu
Coupled ion movement underlies rectification in an inward-rectifier K+ channel.
The Journal of general physiology 1998;112(2):211-21.