Arthur Spector

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Bianco Robert A; Agassandian Khristofor; Cassell Martin D; Spector Arthur A; Sigmund Curt D
Characterization of transgenic mice with neuron-specific expression of soluble epoxide hydrolase.
Spector Arthur A
Arachidonic acid cytochrome P450 epoxygenase pathway.
Kaduce Terry L; Chen Yucui; Hell Johannes W; Spector Arthur A
Docosahexaenoic acid synthesis from n-3 fatty acid precursors in rat hippocampal neurons.

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All Publications

2009: Bianco Robert A; Agassandian Khristofor; Cassell Martin D; Spector Arthur A; Sigmund Curt D
Characterization of transgenic mice with neuron-specific expression of soluble epoxide hydrolase.
Brain research 2009;1291():60-72.
2009: Spector Arthur A
Arachidonic acid cytochrome P450 epoxygenase pathway.
Journal of lipid research 2009;50 Suppl():S52-6.
2008: Kaduce Terry L; Chen Yucui; Hell Johannes W; Spector Arthur A
Docosahexaenoic acid synthesis from n-3 fatty acid precursors in rat hippocampal neurons.
Journal of neurochemistry 2008;105(4):1525-35.
2007: Spector Arthur A; Norris Andrew W
Action of epoxyeicosatrienoic acids on cellular function.
American journal of physiology. Cell physiology 2007;292(3):C996-1012.
2007: Fang Xiang; Dillon Joseph S; Hu Shanming; Harmon Shawn D; Yao Jianrong; Anjaiah Siddam; Falck J R; Spector Arthur A
20-carboxy-arachidonic acid is a dual activator of peroxisome proliferator-activated receptors alpha and gamma.
Prostaglandins & other lipid mediators 2007;82(1-4):175-84.
2006: Fang Xiang; Faraci Frank M; Kaduce Terry L; Harmon Shawn; Modrick Mary L; Hu Shanming; Moore Steven A; Falck J R; Weintraub Neal L; Spector Arthur A
20-Hydroxyeicosatetraenoic acid is a potent dilator of mouse basilar artery: role of cyclooxygenase.
American journal of physiology. Heart and circulatory physiology 2006;291(5):H2301-7.
2006: Harmon Shawn D; Fang Xiang; Kaduce Terry L; Hu Shanming; Raj Gopal V; Falck John R; Spector Arthur A
Oxygenation of omega-3 fatty acids by human cytochrome P450 4F3B: effect on 20-hydroxyeicosatetraenoic acid production.
Prostaglandins, leukotrienes, and essential fatty acids 2006;75(3):169-77.
2006: Zhou Wei; Lu Tong; Spector Arthur A; Lee Hon-Chi
Inhibition of PGI2 signaling by miconazole in vascular smooth muscle cells.
Prostaglandins & other lipid mediators 2006;80(1-2):28-34.
2006: Fang Xiang; Hu Shanming; Xu Bingkun; Snyder Gary D; Harmon Shawn; Yao Jianrong; Liu Yi; Sangras Bhavani; Falck J R; Weintraub Neal L; Spector Arthur A
14,15-Dihydroxyeicosatrienoic acid activates peroxisome proliferator-activated receptor-alpha.
American journal of physiology. Heart and circulatory physiology 2006;290(1):H55-63.
2005: Collins Xixuan H; Harmon Shawn D; Kaduce Terry L; Berst Kristine B; Fang Xiang; Moore Steven A; Raju T Verugopal; Falck John R; Weintraub Neal L; Duester Gregg; Plapp Bryce V; Spector Arthur A
Omega-oxidation of 20-hydroxyeicosatetraenoic acid (20-HETE) in cerebral microvascular smooth muscle and endothelium by alcohol dehydrogenase 4.
The Journal of biological chemistry 2005;280(39):33157-64.
2005: Lu Tong; Wang Xiao-Li; He Tongrong; Zhou Wei; Kaduce Terry L; Katusic Zvonimir S; Spector Arthur A; Lee Hon-Chi
Impaired arachidonic acid-mediated activation of large-conductance Ca2+-activated K+ channels in coronary arterial smooth muscle cells in Zucker Diabetic Fatty rats.
Diabetes 2005;54(7):2155-63.
2005: Fang Xiang; Hu Shanming; Watanabe Takaho; Weintraub Neal L; Snyder Gary D; Yao Jianrong; Liu Yi; Shyy John Y-J; Hammock Bruce D; Spector Arthur A
Activation of peroxisome proliferator-activated receptor alpha by substituted urea-derived soluble epoxide hydrolase inhibitors.
The Journal of pharmacology and experimental therapeutics 2005;314(1):260-70.
2005: Zhou Wei; Wang Xiao-Li; Kaduce Terry L; Spector Arthur A; Lee Hon-Chi
Impaired arachidonic acid-mediated dilation of small mesenteric arteries in Zucker diabetic fatty rats.
American journal of physiology. Heart and circulatory physiology 2005;288(5):H2210-8.
2005: Chen Ping; Hu Shanming; Yao Jianrong; Moore Steven A; Spector Arthur A; Fang Xiang
Induction of cyclooxygenase-2 by anandamide in cerebral microvascular endothelium.
Microvascular research 2005;69(1-2):28-35.
2004: Fang Xiang; Weintraub Neal L; McCaw Ryan B; Hu Shanming; Harmon Shawn D; Rice James B; Hammock Bruce D; Spector Arthur A
Effect of soluble epoxide hydrolase inhibition on epoxyeicosatrienoic acid metabolism in human blood vessels.
American journal of physiology. Heart and circulatory physiology 2004;287(6):H2412-20.
2004: Chen Ping; Hu Shanming; Harmon Shawn D; Moore Steven A; Spector Arthur A; Fang Xiang
Metabolism of anandamide in cerebral microvascular endothelial cells.
Prostaglandins & other lipid mediators 2004;73(1-2):59-72.
2004: Spector Arthur A; Fang Xiang; Snyder Gary D; Weintraub Neal L
Epoxyeicosatrienoic acids (EETs): metabolism and biochemical function.
Progress in lipid research 2004;43(1):55-90.
2004: Kaduce Terry L; Fang Xiang; Harmon Shawn D; Oltman Christine L; Dellsperger Kevin C; Teesch Lynn M; Gopal V Raj; Falck J R; Campbell William B; Weintraub Neal L; Spector Arthur A
20-hydroxyeicosatetraenoic acid (20-HETE) metabolism in coronary endothelial cells.
The Journal of biological chemistry 2004;279(4):2648-56.
2003: Nwankwo Joseph O; Spector Arthur A; Domann Frederick E
A nucleotide insertion in the transcriptional regulatory region of FADS2 gives rise to human fatty acid delta-6-desaturase deficiency.
Journal of lipid research 2003;44(12):2311-9.
2003: Oltman Christine L; Kane Neal L; Miller Francis J; Spector Arthur A; Weintraub Neal L; Dellsperger Kevin C
Reactive oxygen species mediate arachidonic acid-induced dilation in porcine coronary microvessels.
American journal of physiology. Heart and circulatory physiology 2003;285(6):H2309-15.
2003: Widstrom Richard L; Norris Andrew W; Van Der Veer Jon; Spector Arthur A
Fatty acid-binding proteins inhibit hydration of epoxyeicosatrienoic acids by soluble epoxide hydrolase.
Biochemistry 2003;42(40):11762-7.
2003: Harmon Shawn D; Kaduce Terry L; Manuel Tony D; Spector Arthur A
Effect of the delta6-desaturase inhibitor SC-26196 on PUFA metabolism in human cells.
Lipids 2003;38(4):469-76.
2003: Fang Xiang; Weintraub Neal L; Spector Arthur A
Differences in positional esterification of 14,15-epoxyeicosatrienoic acid in phosphatidylcholine of porcine coronary artery endothelial and smooth muscle cells.
Prostaglandins & other lipid mediators 2003;71(1-2):33-42.
2003: Li Wei-Gen; Stoll Lynn L; Rice James B; Xu Shao-Ping; Miller Francis J; Chatterjee Papri; Hu Ling; Oberley Larry W; Spector Arthur A; Weintraub Neal L
Activation of NAD(P)H oxidase by lipid hydroperoxides: mechanism of oxidant-mediated smooth muscle cytotoxicity.
Free radical biology & medicine 2003;34(7):937-46.
2002: Fang Xiang; Weintraub Neal L; Oltman Christine L; Stoll Lynn L; Kaduce Terry L; Harmon Shawn; Dellsperger Kevin C; Morisseau Christophe; Hammock Bruce D; Spector Arthur A
Human coronary endothelial cells convert 14,15-EET to a biologically active chain-shortened epoxide.
American journal of physiology. Heart and circulatory physiology 2002;283(6):H2306-14.
2002: Snyder Gary D; Krishna U Murali; Falck J R; Spector Arthur A
Evidence for a membrane site of action for 14,15-EET on expression of aromatase in vascular smooth muscle.
American journal of physiology. Heart and circulatory physiology 2002;283(5):H1936-42.
2002: Williard D E; Harmon S D; Kaduce T L; Spector A A
Comparison of 20-, 22-, and 24-carbon n-3 and n-6 polyunsaturated fatty acid utilization in differentiated rat brain astrocytes.
Prostaglandins, leukotrienes, and essential fatty acids 2002;67(2-3):99-104.
2002: Norris Andrew W; Spector Arthur A
Very long chain n-3 and n-6 polyunsaturated fatty acids bind strongly to liver fatty acid-binding protein.
Journal of lipid research 2002;43(4):646-53.
2001: Lu T; Hoshi T; Weintraub N L; Spector A A; Lee H C
Activation of ATP-sensitive K(+) channels by epoxyeicosatrienoic acids in rat cardiac ventricular myocytes.
The Journal of physiology 2001;537(Pt 3):811-27.
2001: Williard D E; Harmon S D; Kaduce T L; Preuss M; Moore S A; Robbins M E; Spector A A
Docosahexaenoic acid synthesis from n-3 polyunsaturated fatty acids in differentiated rat brain astrocytes.
Journal of lipid research 2001;42(9):1368-76.
2001: Lu T; Katakam P V; VanRollins M; Weintraub N L; Spector A A; Lee H C
Dihydroxyeicosatrienoic acids are potent activators of Ca(2+)-activated K(+) channels in isolated rat coronary arterial myocytes.
The Journal of physiology 2001;534(Pt 3):651-67.
2001: Rapoport S I; Chang M C; Spector A A
Delivery and turnover of plasma-derived essential PUFAs in mammalian brain.
Journal of lipid research 2001;42(5):678-85.
2001: Fang X; Kaduce T L; Weintraub N L; Harmon S; Teesch L M; Morisseau C; Thompson D A; Hammock B D; Spector A A
Pathways of epoxyeicosatrienoic acid metabolism in endothelial cells. Implications for the vascular effects of soluble epoxide hydrolase inhibition.
The Journal of biological chemistry 2001;276(18):14867-74.
2001: Spector A A
Plasma free fatty acid and lipoproteins as sources of polyunsaturated fatty acid for the brain.
Journal of molecular neuroscience : MN 2001;16(2-3):159-65; discussion 215-21.
2001: Williard D E; Nwankwo J O; Kaduce T L; Harmon S D; Irons M; Moser H W; Raymond G V; Spector A A
Identification of a fatty acid delta6-desaturase deficiency in human skin fibroblasts.
Journal of lipid research 2001;42(4):501-8.
2001: Zink M H; Oltman C L; Lu T; Katakam P V; Kaduce T L; Lee H; Dellsperger K C; Spector A A; Myers P R; Weintraub N L
12-lipoxygenase in porcine coronary microcirculation: implications for coronary vasoregulation.
American journal of physiology. Heart and circulatory physiology 2001;280(2):H693-704.
2001: Widstrom R L; Norris A W; Spector A A
Binding of cytochrome P450 monooxygenase and lipoxygenase pathway products by heart fatty acid-binding protein.
Biochemistry 2001;40(4):1070-6.
2001: Williard D E; Harmon S D; Preuss M A; Kaduce T L; Moore S A; Spector A A
Production and release of docosahexaenoic acid by differentiated rat brain astrocytes.
World review of nutrition and dietetics 2001;88():168-72.
2000: Fang X; Moore A S; Nwankwo J O; Weintraub L N; Oberley W L; Snyder D G; Spector A A
Induction of cyclooxygenase-2 by overexpression of the human catalase gene in cerebral microvascular endothelial cells.
Journal of neurochemistry 2000;75(2):614-23.
2000: Li W G; Miller F J; Brown M R; Chatterjee P; Aylsworth G R; Shao J; Spector A A; Oberley L W; Weintraub N L
Enhanced H(2)O(2)-induced cytotoxicity in "epithelioid" smooth muscle cells: implications for neointimal regression.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(6):1473-9.
2000: Preuss M; Girnun G D; Darby C J; Khoo N; Spector A A; Robbins M E
Role of antioxidant enzyme expression in the selective cytotoxic response of glioma cells to gamma-linolenic acid supplementation.
Free radical biology & medicine 2000;28(7):1143-56.
2000: Fang X; Kaduce T L; VanRollins M; Weintraub N L; Spector A A
Conversion of epoxyeicosatrienoic acids (EETs) to chain-shortened epoxy fatty acids by human skin fibroblasts.
Journal of lipid research 2000;41(1):66-74.
1999: Fang X; Weintraub N L; Stoll L L; Spector A A
Epoxyeicosatrienoic acids increase intracellular calcium concentration in vascular smooth muscle cells.
Hypertension 1999;34(6):1242-6.
1999: Weintraub N L; Fang X; Kaduce T L; VanRollins M; Chatterjee P; Spector A A
Epoxide hydrolases regulate epoxyeicosatrienoic acid incorporation into coronary endothelial phospholipids.
The American journal of physiology 1999;277(5 Pt 2):H2098-108.
1999: Brown M R; Miller F J; Li W G; Ellingson A N; Mozena J D; Chatterjee P; Engelhardt J F; Zwacka R M; Oberley L W; Fang X; Spector A A; Weintraub N L
Overexpression of human catalase inhibits proliferation and promotes apoptosis in vascular smooth muscle cells.
Circulation research 1999;85(6):524-33.
1999: Lee H C; Lu T; Weintraub N L; VanRollins M; Spector A A; Shibata E F
Effects of epoxyeicosatrienoic acids on the cardiac sodium channels in isolated rat ventricular myocytes.
The Journal of physiology 1999;519 Pt 1():153-68.
1999: Spector A A; Willard D E; Kaduce T L; Widstrom R L
Role of peroxisomal oxidation in the conversion of arachidonic acid to eicosatrienoic acid in human skin fibroblasts.
Prostaglandins, leukotrienes, and essential fatty acids 1999;60(5-6):377-82.
1999: Fang X; Kaduce T L; Spector A A
13-(S)-hydroxyoctadecadienoic acid (13-HODE) incorporation and conversion to novel products by endothelial cells.
Journal of lipid research 1999;40(4):699-707.
1999: Vartak S; Robbins M E; Spector A A
The selective cytotoxicity of gamma-linolenic acid (GLA) is associated with increased oxidative stress.
Advances in experimental medicine and biology 1999;469():493-8.
1999: Spector A A
Essentiality of fatty acids.
Lipids 1999;34 Suppl():S1-3.
1998: Fang X; Moore S A; Stoll L L; Rich G; Kaduce T L; Weintraub N L; Spector A A
14,15-Epoxyeicosatrienoic acid inhibits prostaglandin E2 production in vascular smooth muscle cells.
The American journal of physiology 1998;275(6 Pt 2):H2113-21.
1998: Fang X; Weintraub N L; Rios C D; Chappell D A; Zwacka R M; Engelhardt J F; Oberley L W; Yan T; Heistad D D; Spector A A
Overexpression of human superoxide dismutase inhibits oxidation of low-density lipoprotein by endothelial cells.
Circulation research 1998;82(12):1289-97.
1998: Vartak S; McCaw R; Davis C S; Robbins M E; Spector A A
Gamma-linolenic acid (GLA) is cytotoxic to 36B10 malignant rat astrocytoma cells but not to 'normal' rat astrocytes.
British journal of cancer 1998;77(10):1612-20.
1998: Williard D E; Kaduce T L; Harmon S D; Spector A A
Conversion of eicosapentaenoic acid to chain-shortened omega-3 fatty acid metabolites by peroxisomal oxidation.
Journal of lipid research 1998;39(5):978-86.
1997: Fang X; Kaduce T L; Weintraub N L; Spector A A
Cytochrome P450 metabolites of arachidonic acid: rapid incorporation and hydration of 14,15-epoxyeicosatrienoic acid in arterial smooth muscle cells.
Prostaglandins, leukotrienes, and essential fatty acids 1997;57(4-5):367-71.
1997: Weintraub N L; Fang X; Kaduce T L; VanRollins M; Chatterjee P; Spector A A
Potentiation of endothelium-dependent relaxation by epoxyeicosatrienoic acids.
Circulation research 1997;81(2):258-67.
1997: Spector A A; Williard D E; Kaduce T L; Gordon J A
Conversion of arachidonic acid to tetradecadienoic acid by peroxisomal oxidation.
Prostaglandins, leukotrienes, and essential fatty acids 1997;57(1):101-5.
1997: Ek B A; Cistola D P; Hamilton J A; Kaduce T L; Spector A A
Fatty acid binding proteins reduce 15-lipoxygenase-induced oxygenation of linoleic acid and arachidonic acid.
Biochimica et biophysica acta 1997;1346(1):75-85.
1997: Vartak S; Robbins M E; Spector A A
Polyunsaturated fatty acids increase the sensitivity of 36B10 rat astrocytoma cells to radiation-induced cell kill.
Lipids 1997;32(3):283-92.
1996: Martin D D; Robbins M E; Spector A A; Wen B C; Hussey D H
The fatty acid composition of human gliomas differs from that found in nonmalignant brain tissue.
Lipids 1996;31(12):1283-8.
1996: Fang X; Kaduce T L; Weintraub N L; VanRollins M; Spector A A
Functional implications of a newly characterized pathway of 11,12-epoxyeicosatrienoic acid metabolism in arterial smooth muscle.
Circulation research 1996;79(4):784-93.
1996: VanRollins M; Kaduce T L; Fang X; Knapp H R; Spector A A
Arachidonic acid diols produced by cytochrome P-450 monooxygenases are incorporated into phospholipids of vascular endothelial cells.
The Journal of biological chemistry 1996;271(24):14001-9.
1995: Stoll L L; Spector A A
Functional and ultrastructural effects of essential fatty acid deficiency in kidney epithelial cells.
Lipids 1995;30(12):1098-103.
1995: Moore S A; Hurt E; Yoder E; Sprecher H; Spector A A
Docosahexaenoic acid synthesis in human skin fibroblasts involves peroxisomal retroconversion of tetracosahexaenoic acid.
Journal of lipid research 1995;36(11):2433-43.
1995: Fang X; VanRollins M; Kaduce T L; Spector A A
Epoxyeicosatrienoic acid metabolism in arterial smooth muscle cells.
Journal of lipid research 1995;36(6):1236-46.
1995: Gordon J A; Heller S K; Rhead W J; Watkins P A; Spector A A
Formation of a novel arachidonic acid metabolite in peroxisomes.
Prostaglandins, leukotrienes, and essential fatty acids 1995;52(2-3):77-81.
1994: Mallampalli R K; Salome R G; Spector A A
Regulation of CTP:choline-phosphate cytidylyltransferase by polyunsaturated n-3 fatty acids.
The American journal of physiology 1994;267(6 Pt 1):L641-8.
1994: Alexander-North L S; North J A; Kiminyo K P; Buettner G R; Spector A A
Polyunsaturated fatty acids increase lipid radical formation induced by oxidant stress in endothelial cells.
Journal of lipid research 1994;35(10):1773-85.
1994: North J A; Spector A A; Buettner G R
Cell fatty acid composition affects free radical formation during lipid peroxidation.
The American journal of physiology 1994;267(1 Pt 1):C177-88.
1994: Stoll L L; Morland M R; Spector A A
13-HODE increases intracellular calcium in vascular smooth muscle cells.
The American journal of physiology 1994;266(4 Pt 1):C990-6.
1994: Girton R A; Spector A A; Gordon J A
15-HETE: selective incorporation into inositol phospholipids of MDCK cells.
Kidney international 1994;45(4):972-80.
1994: Gordon J A; Broekemeier K M; Spector A A; Pfeiffer D R
Mitochondrial metabolism of 12- and 15-hydroxyeicosatetraenoic acids.
Journal of lipid research 1994;35(4):698-708.
1994: Gordon J A; Heller S K; Kaduce T L; Spector A A
Formation and release of a peroxisome-dependent arachidonic acid metabolite by human skin fibroblasts.
The Journal of biological chemistry 1994;269(6):4103-9.
1994: Spector A A; Gordon J A; Moore S A
Beta-oxidation of hydroxyeicosatetraenoic acids: a peroxisomal process.
World review of nutrition and dietetics 1994;75():8-15.
1994: Spector A A; North J A; Cornelius A S; Buettner G R
Possible applications of polyunsaturated fatty acids in cancer therapy.
World review of nutrition and dietetics 1994;76():81-5.
1993: VanRollins M; Kaduce T L; Knapp H R; Spector A A
14,15-Epoxyeicosatrienoic acid metabolism in endothelial cells.
Journal of lipid research 1993;34(11):1931-42.
1993: Gordon J A; Warnock L J; Spector A A
Attenuated prostaglandin formation in peroxisomal-deficient human skin fibroblasts.
The Journal of clinical investigation 1993;92(1):169-78.
1993: Hempel S L; Wessels D A; Spector A A
Effect of glutathione on endothelial prostacyclin synthesis after anoxia.
The American journal of physiology 1993;264(6 Pt 1):C1448-57.
1993: Stoll L L; Spector A A
Lysophosphatidylcholine causes cGMP-dependent verapamil-sensitive Ca2+ influx in vascular smooth muscle cells.
The American journal of physiology 1993;264(4 Pt 1):C885-93.
1992: Wang L; Yerram N R; Kaduce T L; Spector A A
Myristic acid utilization in Chinese hamster ovary cells and peroxisome-deficient mutants.
The Journal of biological chemistry 1992;267(26):18983-90.
1992: Stoll L L; Oskarsson H J; Spector A A
Interaction of lysophosphatidylcholine with aortic endothelial cells.
The American journal of physiology 1992;262(6 Pt 2):H1853-60.
1992: North J A; Spector A A; Buettner G R
Detection of lipid radicals by electron paramagnetic resonance spin trapping using intact cells enriched with polyunsaturated fatty acid.
The Journal of biological chemistry 1992;267(9):5743-6.
1991: Cornelius A S; Yerram N R; Kratz D A; Spector A A
Cytotoxic effect of cis-parinaric acid in cultured malignant cells.
Cancer research 1991;51(22):6025-30.
1991: Gordon E E; Gordon J A; Spector A A
HETEs and coronary artery endothelial cells: metabolic and functional interactions.
The American journal of physiology 1991;261(4 Pt 1):C623-33.
1991: Moore S A; Giordano M J; Kim H Y; Salem N; Spector A A
Brain microvessel 12-hydroxyeicosatetraenoic acid is the (S) enantiomer and is lipoxygenase derived.
Journal of neurochemistry 1991;57(3):922-9.
1991: Stoll L L; Yerram N R; Spector A A
Effect of differentiation on platelet-activating factor metabolism in HL-60 cells.
Journal of cell science 1991;100 ( Pt 1)():145-52.
1991: Gordon J A; Zoeller R A; Spector A A
Hydroxyeicosatetraenoic acid oxidation in Chinese hamster ovary cells: a peroxisomal metabolic pathway.
Biochimica et biophysica acta 1991;1085(1):21-8.
1991: Wang L X; Kaduce T L; Spector A A
Myristic acid utilization and processing in BC3H1 muscle cells.
The Journal of biological chemistry 1991;266(21):13883-90.
1991: Moore S A; Yoder E; Murphy S; Dutton G R; Spector A A
Astrocytes, not neurons, produce docosahexaenoic acid (22:6 omega-3) and arachidonic acid (20:4 omega-6).
Journal of neurochemistry 1991;56(2):518-24.
1990: Wang L X; Kaduce T L; Spector A A
Localization of 12-hydroxyeicosatetraenoic acid in endothelial cells.
Journal of lipid research 1990;31(12):2265-76.
1990: Hempel S L; Haycraft D L; Hoak J C; Spector A A
Reduced prostacyclin formation after reoxygenation of anoxic endothelium.
The American journal of physiology 1990;259(5 Pt 1):C738-45.
1990: Moore S A; Yoder E; Spector A A
Role of the blood-brain barrier in the formation of long-chain omega-3 and omega-6 fatty acids from essential fatty acid precursors.
Journal of neurochemistry 1990;55(2):391-402.
1990: Gordon J A; Figard P H; Spector A A
Hydroxyeicosatetraenoic acid metabolism in cultured human skin fibroblasts. Evidence for peroxisomal beta-oxidation.
The Journal of clinical investigation 1990;85(4):1173-81.
1989: Yerram N R; Moore S A; Spector A A
Eicosapentaenoic acid metabolism in brain microvessel endothelium: effect on prostaglandin formation.
Journal of lipid research 1989;30(11):1747-57.
1989: Stoll L L; Figard P H; Yerram N R; Yorek M A; Spector A A
1-O-alkyl-2-acetyl-sn-glycerol: a platelet-activating factor metabolite with biological activity in vascular smooth muscle cells.
Cell regulation 1989;1(1):13-25.
1989: Moore S A; Figard P H; Spector A A; Hart M N
Brain microvessels produce 12-hydroxyeicosatetraenoic acid.
Journal of neurochemistry 1989;53(2):376-82.
1989: Yerram N R; Spector A A
Effects of omega-3 fatty acids on vascular smooth muscle cells: reduction in arachidonic acid incorporation into inositol phospholipids.
Lipids 1989;24(7):594-602.
1989: Gordon J A; Figard P H; Spector A A
Identification of the major metabolite of 12-HETE produced by renal tubular epithelial cells.
Journal of lipid research 1989;30(5):731-8.
1989: Stoll L L; Spector A A
Interaction of platelet-activating factor with endothelial and vascular smooth muscle cells in coculture.
Journal of cellular physiology 1989;139(2):253-61.
1989: Kaduce T L; Figard P H; Leifur R; Spector A A
Formation of 9-hydroxyoctadecadienoic acid from linoleic acid in endothelial cells.
The Journal of biological chemistry 1989;264(12):6823-30.
1989: Gordon J A; Figard P H; Quinby G E; Spector A A
5-HETE: uptake, distribution, and metabolism in MDCK cells.
The American journal of physiology 1989;256(1 Pt 1):C1-10.
1988: Moore S A; Prokuski L J; Figard P H; Spector A A; Hart M N
Murine cerebral microvascular endothelium incorporate and metabolize 12-hydroxyeicosatetraenoic acid.
Journal of cellular physiology 1988;137(1):75-85.
1988: Spector A A
Lipid and lipoprotein effects on endothelial eicosanoid formation.
Seminars in thrombosis and hemostasis 1988;14(2):196-201.
1988: Shen X Y; Figard P H; Kaduce T L; Spector A A
Conversion of 15-hydroxyeicosatetraenoic acid to 11-hydroxyhexadecatrienoic acid by endothelial cells.
Biochemistry 1988;27(3):996-1004.
1988: Moore S A; Spector A A; Hart M N
Eicosanoid metabolism in cerebromicrovascular endothelium.
The American journal of physiology 1988;254(1 Pt 1):C37-44.
1988: Spector A A; Gordon J A; Moore S A
Hydroxyeicosatetraenoic acids (HETEs).
Progress in lipid research 1988;27(4):271-323.
1987: Shasby D M; Stoll L L; Spector A A
Polarity of arachidonic acid metabolism by bovine aortic endothelial cell monolayers.
The American journal of physiology 1987;253(5 Pt 2):H1177-83.
1987: Hadjiagapiou C; Sprecher H; Kaduce T L; Figard P H; Spector A A
Formation of 8-hydroxyhexadecatrienoic acid by vascular smooth muscle cells.
Prostaglandins 1987;34(4):579-89.
1987: Stoll L L; Spector A A
Lipid transfer between endothelial and smooth muscle cells in coculture.
Journal of cellular physiology 1987;133(1):103-10.
1987: Dudley D T; Macfarlane D E; Spector A A
Depletion of arachidonic acid from GH3 cells. Effects on inositol phospholipid turnover and cellular activation.
The Biochemical journal 1987;246(3):669-79.
1986: Figard P H; Hejlik D P; Kaduce T L; Stoll L L; Spector A A
Free fatty acid release from endothelial cells.
Journal of lipid research 1986;27(7):771-80.
1986: Mann C J; Kaduce T L; Figard P H; Spector A A
Docosatetraenoic acid in endothelial cells: formation, retroconversion to arachidonic acid, and effect on prostacyclin production.
Archives of biochemistry and biophysics 1986;244(2):813-23.
1985: Sandra A; Bar R S; Dolash S; Marshall S J; Kaduce T L; Spector A A
Morphological alterations in cultured endothelial cells induced by arachidonic acid.
Experimental cell research 1985;158(2):484-92.
1985: Spector A A; Scanu A M; Kaduce T L; Figard P H; Fless G M; Czervionke R L
Effect of human plasma lipoproteins on prostacyclin production by cultured endothelial cells.
Journal of lipid research 1985;26(3):288-97.
1984: Bar R S; Dolash S; Spector A A; Kaduce T L; Figard P H
Effects of membrane lipid unsaturation on the interactions of insulin and multiplication stimulating activity with endothelial cells.
Biochimica et biophysica acta 1984;804(4):466-73.
1983: Spector A A; Kaduce T L; Figard P H; Norton K C; Hoak J C; Czervionke R L
Eicosapentaenoic acid and prostacyclin production by cultured human endothelial cells.
Journal of lipid research 1983;24(12):1595-604.
1983: Denning G M; Figard P H; Kaduce T L; Spector A A
Role of triglycerides in endothelial cell arachidonic acid metabolism.
Journal of lipid research 1983;24(8):993-1001.
1983: Spector A A; Kaduce T L; Hoak J C; Czervionke R L
Arachidonic acid availability and prostacyclin production by cultured human endothelial cells.
Arteriosclerosis (Dallas, Tex.) 1983;3(4):323-31.
1982: Denning G M; Figard P H; Spector A A
Effect of fatty acid modification on prostaglandin production by cultured 3T3 cells.
Journal of lipid research 1982;23(4):584-96.
1981: Spector A A; Kaduce T L; Hoak J C; Fry G L
Utilization of arachidonic and linoleic acids by cultured human endothelial cells.
The Journal of clinical investigation 1981;68(4):1003-11.
1981: Spector A A; Hoak J C; Fry G L; Stoll L L; Tanke C T; Kaduce T L
Essential fatty acid availability and prostacyclin production by cultured human endothelial cells.
Progress in lipid research 1981;20():471-7.
1980: Spector A A; Denning G M; Stoll L L
Retention of human skin fibroblast fatty acid modifications during maintenance culture.
In vitro 1980;16(11):932-40.
1980: Spector A A; Hoak J C; Fry G L; Denning G M; Stoll L L; Smith J B
Effect of fatty acid modification on prostacyclin production by cultured human endothelial cells.
The Journal of clinical investigation 1980;65(5):1003-12.

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