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Daniel Speiser

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Stéphanie Corgnac; Laurent Derré; Jean-Pierre Mach; Rachel Perret; Pedro Romero; Daniel E Speiser; Kathrin Stirnemann; Maurice Zauderer; Lianjun Zhang; Alena Donda
CD1d-antibody fusion proteins target iNKT cells to the tumor and trigger long-term therapeutic responses.
Michael Hebeisen; Olivier Michielin; Danilo Presotto; Pedro Romero; Lukas Baitsch; Petra Baumgaertner; Daniel E Speiser; Nathalie Rufer
SHP-1 phosphatase activity counteracts increased T cell receptor affinity.
Marie-Laure Thibult; Sonia Pastor; Jean-Paul Rivals; Daniel E Speiser; Laurent Derré; Julie Gertner-Dardenne; Emilie Mamessier; Daniel Olive
CpG-ODN-induced sustained expression of BTLA mediating selective inhibition of human B cells.

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2013: Stéphanie Corgnac; Laurent Derré; Jean-Pierre Mach; Rachel Perret; Pedro Romero; Daniel E Speiser; Kathrin Stirnemann; Maurice Zauderer; Lianjun Zhang; Alena Donda
CD1d-antibody fusion proteins target iNKT cells to the tumor and trigger long-term therapeutic responses.
Cancer immunology, immunotherapy : CII 2013;62(4):747-60.
2013: Michael Hebeisen; Olivier Michielin; Danilo Presotto; Pedro Romero; Lukas Baitsch; Petra Baumgaertner; Daniel E Speiser; Nathalie Rufer
SHP-1 phosphatase activity counteracts increased T cell receptor affinity.
The Journal of clinical investigation 2013;123(3):1044-56.
2013: Marie-Laure Thibult; Sonia Pastor; Jean-Paul Rivals; Daniel E Speiser; Laurent Derré; Julie Gertner-Dardenne; Emilie Mamessier; Daniel Olive
CpG-ODN-induced sustained expression of BTLA mediating selective inhibition of human B cells.
Journal of molecular medicine (Berlin, Germany) 2013;91(2):195-205.
2013: Luc Bron; Camilla Jandus; Philippe Monnier; Pedro Romero; Daniel E Speiser; Snezana Andrejevic-Blant; Jean-Paul Rivals
Prognostic value of arginase-II expression and regulatory T-cell infiltration in head and neck squamous cell carcinoma.
International journal of cancer. Journal international du cancer 2013;132(3):E85-93.
2013: Julien Laurent; Bernd Liedert; Aurelius Omlin; Stefano Ongarello; Sonia Quaratino; Cristiana Sessa; Joachim Beck; Caroline Bertrand; Elisa Gallerani; Silke Gillessen; Ulrike S Gnad-Vogt; Magali Joffraud; Roger Stupp; Cedric Touvrey; Manuela Vicari; Daniel E Speiser
T-cell activation by treatment of cancer patients with EMD 521873 (Selectikine), an IL-2/anti-DNA fusion protein.
Journal of translational medicine 2013;11():5.
2012: Silvia A Fuertes Marraco; Amandine Legat; Nathalie Rufer; Petra Baumgaertner; Daniel E Speiser
A stepwise protocol to coat aAPC beads prevents out-competition of anti-CD3 mAb and consequent experimental artefacts.
Journal of immunological methods 2012;385(1-2):90-5.
2012: Simone M Goldinger; Anya Hammann-Haenni; Thomas M Kündig; Olivier Michielin; Daniela Mihic-Probst; John O Prior; Katrin Schwarz; Martin F Bachmann; Petra Baumgaertner; Reinhard Dummer; Christine Geldhof; Jörg Willers; Daniel E Speiser
Nano-particle vaccination combined with TLR-7 and -9 ligands triggers memory and effector CD8⁺ T-cell responses in melanoma patients.
European journal of immunology 2012;42(11):3049-61.
2012: Lukas Baitsch; Silvia A Fuertes-Marraco; Amandine Legat; Christiane Meyer; Daniel E Speiser
The three main stumbling blocks for anticancer T cells.
Trends in immunology 2012;33(7):364-72.
2012: Tanja Lövgren; Immanuel F Luescher; Nathalie Rufer; Petra Baumgaertner; Estelle Devêvre; Philippe Guillaume; Sébastien Wieckowski; Daniel E Speiser
Enhanced cytotoxicity and decreased CD8 dependence of human cancer-specific cytotoxic T lymphocytes after vaccination with low peptide dose.
Cancer immunology, immunotherapy : CII 2012;61(6):817-26.
2012: Petra Baumgaertner; Gregoire Berthod; Laurent Derré; Philippe Guillaume; Camilla Jandus; Tanja Lövgren; Immanuel F Luescher; Maurice Matter; Olivier Michielin; Jean-Paul Rivals; Nathalie Rufer; Lukas Baitsch; Daniel E Speiser
Vaccination-induced functional competence of circulating human tumor-specific CD8 T-cells.
International journal of cancer. Journal international du cancer 2012;130(11):2607-17.
2012: Marion Braun; Anya Hammann-Haenni; Camilla Jandus; Patrik Maurer; Katrin Schwarz; Daniel E Speiser; Martin F Bachmann; Pedro Romero
Virus-like particles induce robust human T-helper cell responses.
European journal of immunology 2012;42(2):330-40.
2012: Lukas Baitsch; Leticia Barba; Petra Baumgaertner; Hanifa Bouzourene; Céline Christiansen-Jucht; Silvia A Fuertes Marraco; Amandine Legat; Maurice Matter; Olivier Michielin; Hanspeter Pircher; Donata Rimoldi; Jean-Paul Rivals; Nathalie Rufer; Daniel E Speiser
Extended co-expression of inhibitory receptors by human CD8 T-cells depending on differentiation, antigen-specificity and anatomical localization.
PloS one 2012;7(2):e30852.
2011: Daniel E Speiser; Sébastien Wieckowski; Lukas Baitsch; Petra Baumgaertner; Bhawna Gupta; Emanuela M Iancu; Olivier Michielin; Pedro Romero; Nathalie Rufer
Single cell analysis reveals similar functional competence of dominant and nondominant CD8 T-cell clonotypes.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(37):15318-23.
2011: Lukas Baitsch; Petra Baumgaertner; Estelle Devêvre; Sunil K Raghav; Amandine Legat; Leticia Barba; Sébastien Wieckowski; Hanifa Bouzourene; Bart Deplancke; Pedro Romero; Nathalie Rufer; Daniel E Speiser
Exhaustion of tumor-specific CD8⁺ T cells in metastases from melanoma patients.
The Journal of clinical investigation 2011;121(6):2350-60.
2011: Emanuela M Iancu; Petra Baumgaertner; Sébastien Wieckowski; Daniel E Speiser; Nathalie Rufer
Profile of a serial killer: cellular and molecular approaches to study individual cytotoxic T-cells following therapeutic vaccination.
Journal of biomedicine & biotechnology 2011;2011():452606.
2010: Daniel E Speiser; Katrin Schwarz; Petra Baumgaertner; Vania Manolova; Estelle Devevre; Wolfram Sterry; Peter Walden; Alfred Zippelius; Katrin Baumann Conzett; Gabriela Senti; Verena Voelter; Jean-Philippe Cerottini; David Guggisberg; Jörg Willers; Christine Geldhof; Pedro Romero; Thomas Kündig; Alexander Knuth; Reinhard Dummer; Uwe Trefzer; Martin F Bachmann
Memory and effector CD8 T-cell responses after nanoparticle vaccination of melanoma patients.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2010;33(8):848-58.
2010: julien laurent; Daniel E Speiser; Victor Appay; Cedric Touvrey; Manuela Vicari; Anne Papaioannou; Giorgia Canellini; Donata Rimoldi; Nathalie Rufer; Pedro Romero; Serge Leyvraz; Verena Voelter
Impact of 3 different short-term chemotherapy regimens on lymphocyte-depletion and reconstitution in melanoma patients.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2010;33(7):723-34.
2010: Philippe Guillaume; Petra Baumgaertner; Laurence Neff; Nathalie Rufer; Peter Wettstein; Daniel E Speiser; Immanuel F Luescher
Novel soluble HLA-A2/MELAN-A complexes selectively stain a differentiation defective subpopulation of CD8+ T cells in patients with melanoma.
International journal of cancer. Journal international du cancer 2010;127(4):910-23.
2010: Daniel E Speiser; Pedro Romero
Molecularly defined vaccines for cancer immunotherapy, and protective T cell immunity.
Seminars in immunology 2010;22(3):144-54.
2010: Laurent Derré; Camilla Jandus; Petra Baumgaertner; Vilmos Posevitz; Estelle Devêvre; Pedro Romero; Daniel E Speiser
Quantitative multiparameter assays to measure the effect of adjuvants on human antigen-specific CD8 T-cell responses.
Methods in molecular biology (Clifton, N.J.) 2010;626():231-49.
2010: Laurent Derré; Jean-Paul Rivals; Camilla Jandus; Sonia Pastor; Donata Rimoldi; Pedro Romero; Olivier Michielin; Daniel Olive; Daniel E Speiser
BTLA mediates inhibition of human tumor-specific CD8+ T cells that can be partially reversed by vaccination.
The Journal of clinical investigation 2010;120(1):157-67.
2009: Camilla Jandus; Gilles Bioley; Danijel Dojcinovic; Laurent Derré; Lukas Baitsch; Sébastien Wieckowski; Nathalie Rufer; William W Kwok; Jean-Marie Tiercy; Immanuel F Luescher; Daniel E Speiser; Pedro Romero
Tumor antigen-specific FOXP3+ CD4 T cells identified in human metastatic melanoma: peptide vaccination results in selective expansion of Th1-like counterparts.
Cancer research 2009;69(20):8085-93.
2009: Sébastien Wieckowski; Petra Baumgaertner; Patricia Corthesy; Verena Voelter; Pedro Romero; Daniel E Speiser; Nathalie Rufer
Fine structural variations of alphabetaTCRs selected by vaccination with natural versus altered self-antigen in melanoma patients.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(8):5397-406.
2009: Danielle Lienard; Marie-Françoise Avril; Frédérique-Anne Le Gal; Petra Baumgaertner; Wim Vermeulen; Astrid Blom; Christine Geldhof; Donata Rimoldi; sonia pagliusi; Pedro Romero; Pierre-Yves Dietrich; Nathalie Corvaia; Daniel E Speiser
Vaccination of melanoma patients with Melan-A/Mart-1 peptide and Klebsiella outer membrane protein p40 as an adjuvant.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2009;32(8):875-83.
2009: Emanuela M Iancu; Patricia Corthesy; Petra Baumgaertner; Estelle Devevre; Verena Voelter; Pedro Romero; Daniel E Speiser; Nathalie Rufer
Clonotype selection and composition of human CD8 T cells specific for persistent herpes viruses varies with differentiation but is stable over time.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(1):319-31.
2009: Cedric Touvrey; Laurent Derré; Estelle Devevre; Patricia Corthesy; Pedro Romero; Nathalie Rufer; Daniel E Speiser
Dominant human CD8 T cell clonotypes persist simultaneously as memory and effector cells in memory phase.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(11):6718-26.
2009: Gabriel Bricard; Valerie Cesson; Estelle Devevre; Hanifa Bouzourene; Catherine Barbey; Nathalie Rufer; Jin S Im; Pedro M S Alves; Olivier Martinet; Nermin Halkic; Jean-Charles Cerottini; Pedro Romero; Steven A Porcelli; H Robson MacDonald; Daniel E Speiser
Enrichment of human CD4+ V(alpha)24/Vbeta11 invariant NKT cells in intrahepatic malignant tumors.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(8):5140-51.
2008: Camilla Jandus; Gilles Bioley; Daniel E Speiser; Pedro Romero
Selective accumulation of differentiated FOXP3(+) CD4 (+) T cells in metastatic tumor lesions from melanoma patients compared to peripheral blood.
Cancer immunology, immunotherapy : CII 2008;57(12):1795-805.
2008: Laurent Derré; Marc Bruyninx; Petra Baumgaertner; Mathias Ferber; Daphné Schmid; Antoine Leimgruber; Vincent Zoete; Pedro Romero; Olivier Michielin; Daniel E Speiser; Nathalie Rufer
Distinct sets of alphabeta TCRs confer similar recognition of tumor antigen NY-ESO-1157-165 by interacting with its central Met/Trp residues.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(39):15010-5.
2008: Daniel E Speiser; Petra Baumgaertner; Verena Voelter; Estelle Devevre; Catherine Barbey; Nathalie Rufer; Pedro Romero
Unmodified self antigen triggers human CD8 T cells with stronger tumor reactivity than altered antigen.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(10):3849-54.
2008: Verena Voelter; Alessia Pica; julien laurent; Donata Rimoldi; Hanifa Bouzourene; Ali Sajadi; Maurice Matter; Pedro Romero; Nathalie Rufer; Daniel E Speiser
An unusual case of metastatic melanoma sensitive to chemotherapy and immunotherapy, with late immune escape in the brain.
Cancer immunity 2008;8():6.
2007: Laurent Derré; Mathias Ferber; Cedric Touvrey; Estelle Devevre; Vincent Zoete; Antoine Leimgruber; Pedro Romero; Olivier Michielin; Frédéric Lévy; Daniel E Speiser
A novel population of human melanoma-specific CD8 T cells recognizes Melan-AMART-1 immunodominant nonapeptide but not the corresponding decapeptide.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(11):7635-45.
2007: Pedro M S Alves; Sebastien Viatte; Theres Fagerberg; Olivier Michielin; Gabriel Bricard; Hanifa Bouzourene; Henri Vuilleumier; Thorsten Kruger; Jean-Claude Givel; Frédéric Lévy; Daniel E Speiser; Jean-Charles Cerottini; Pedro Romero
Immunogenicity of the carcinoembryonic antigen derived peptide 694 in HLA-A2 healthy donors and colorectal carcinoma patients.
Cancer immunology, immunotherapy : CII 2007;56(11):1795-805.
2007: Laurent Derré; Marc Bruyninx; Petra Baumgaertner; Estelle Devevre; Patricia Corthesy; Cedric Touvrey; Yolanda D Mahnke; Hanspeter Pircher; Verena Voelter; Pedro Romero; Daniel E Speiser; Nathalie Rufer
In Vivo Persistence of Codominant Human CD8+ T Cell Clonotypes Is Not Limited by Replicative Senescence or Functional Alteration.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(4):2368-79.
2007: Pedro M S Alves; Nicole Lévy; Hanifa Bouzourene; Sebastien Viatte; Gabriel Bricard; Maha Ayyoub; Henri Vuilleumier; Jean-Claude Givel; Nermin Halkic; Daniel E Speiser; Pedro Romero; Frédéric Lévy
Molecular and immunological evaluation of the expression of cancer/testis gene products in human colorectal cancer.
Cancer immunology, immunotherapy : CII 2007;56(6):839-47.
2007: Pedro Romero; Alfred Zippelius; Isabel Kurth; Mikaël J Pittet; Cedric Touvrey; Emanuela M Iancu; Patricia Corthesy; Estelle Devevre; Daniel E Speiser; Nathalie Rufer
Four functionally distinct populations of human effector-memory CD8+ T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(7):4112-9.
2007: Catherine Barbey; Petra Baumgaertner; Estelle Devevre; Verena Rubio-Godoy; Laurent Derré; Gabriel Bricard; Philippe Guillaume; Immanuel F Luescher; Danielle Liénard; Jean-Charles Cerottini; Pedro Romero; Nathalie Rufer; Daniel E Speiser
IL-12 controls cytotoxicity of a novel subset of self-antigen-specific human CD28+ cytolytic T cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(6):3566-74.
2007: Frédérique-Anne Le Gal; Valérie M Widmer; Valérie Dutoit; Verena Rubio-Godoy; jacques schrenzel; Paul R Walker; Pedro J Romero; Danila Valmori; Daniel E Speiser; Pierre-Yves Dietrich
Tissue homing and persistence of defined antigen-specific CD8+ tumor-reactive T-cell clones in long-term melanoma survivors.
The Journal of investigative dermatology 2007;127(3):622-9.
2007: Victor Appay; Verena Voelter; Nathalie Rufer; Severine Reynard; Camilla Jandus; Danielle Gasparini; Danielle Lienard; Daniel E Speiser; Philippe Schneider; Jean-Charles Cerottini; Pedro Romero; Serge Leyvraz
Combination of transient lymphodepletion with busulfan and fludarabine and peptide vaccination in a phase I clinical trial for patients with advanced melanoma.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2007;30(2):240-50.
2006: Gilles Bioley; Camilla Jandus; Sandra Tuyaerts; Donata Rimoldi; William W Kwok; Daniel E Speiser; Jean-Marie Tiercy; Kris Thielemans; Jean-Charles Cerottini; Pedro Romero
Melan-A/MART-1-specific CD4 T cells in melanoma patients: identification of new epitopes and ex vivo visualization of specific T cells by MHC class II tetramers.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(10):6769-79.
2006: Victor Appay; Camilla Jandus; Verena Voelter; Severine Reynard; Sarah E Coupland; Donata Rimoldi; Danielle Lienard; Philippe Guillaume; Arthur M Krieg; Jean-Charles Cerottini; Pedro Romero; Serge Leyvraz; Nathalie Rufer; Daniel E Speiser
New generation vaccine induces effective melanoma-specific CD8+ T cells in the circulation but not in the tumor site.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(3):1670-8.
2006: Daniel E Speiser; Petra Baumgaertner; Catherine Barbey; Verena Rubio-Godoy; Alexandre Moulin; Patricia Corthesy; Estelle Devevre; Pierre-Yves Dietrich; Donata Rimoldi; Danielle Liénard; Jean-Charles Cerottini; Pedro Romero; Nathalie Rufer
A novel approach to characterize clonality and differentiation of human melanoma-specific T cell responses: spontaneous priming and efficient boosting by vaccination.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(2):1338-48.
2006: Victor Appay; Daniel E Speiser; Nathalie Rufer; Severine Reynard; Catherine Barbey; Jean-Charles Cerottini; Serge Leyvraz; Clemencia Pinilla; Pedro Romero
Decreased specific CD8+ T cell cross-reactivity of antigen recognition following vaccination with Melan-A peptide.
European journal of immunology 2006;36(7):1805-14.
2006: Sara Colombetti; Theres Fagerberg; Petra Baumgärtner; Laurence Chapatte; Daniel E Speiser; Nathalie Rufer; Olivier Michielin; Frédéric Lévy
Impact of orthologous melan-A peptide immunizations on the anti-self melan-A/HLA-A2 T cell cross-reactivity.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(11):6560-7.
2006: Pascal Batard; Daniel A Peterson; Estelle Devêvre; Philippe Guillaume; Jean-Charles Cerottini; Donata Rimoldi; Daniel E Speiser; Lars Winther; Pedro Romero
Dextramers: new generation of fluorescent MHC class I/peptide multimers for visualization of antigen-specific CD8+ T cells.
Journal of immunological methods 2006;310(1-2):136-48.
2006: Victor Appay; Severine Reynard; Verena Voelter; Pedro Romero; Daniel E Speiser; Serge Leyvraz
Immuno-monitoring of CD8+ T cells in whole blood versus PBMC samples.
Journal of immunological methods 2006;309(1-2):192-9.
2006: Petra Baumgaertner; Nathalie Rufer; Estelle Devevre; Laurent Derré; Donata Rimoldi; Christine Geldhof; Verena Voelter; Danielle Liénard; Pedro Romero; Daniel E Speiser
Ex vivo detectable human CD8 T-cell responses to cancer-testis antigens.
Cancer research 2006;66(4):1912-6.
2006: Mikaël J Pittet; Asma Gati; Frédérique-Anne Le Gal; Gilles Bioley; Philippe Guillaume; Magda De Smedt; Jean Plum; Daniel E Speiser; Jean-Charles Cerottini; Pierre-Yves Dietrich; Pedro Romero; Alfred Zippelius
Ex vivo characterization of allo-MHC-restricted T cells specific for a single MHC-peptide complex.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(4):2330-6.
2006: Pedro Romero; Jean-Charles Cerottini; Daniel E Speiser
The human T cell response to melanoma antigens.
Advances in immunology 2006;92():187-224.
2005: Daniel E Speiser; Pedro Romero
Toward improved immunocompetence of adoptively transferred CD8+ T cells.
The Journal of clinical investigation 2005;115(6):1467-9.
2005: Daniel E Speiser; Danielle Liénard; Nathalie Rufer; Verena Rubio-Godoy; Donata Rimoldi; Ferdy Lejeune; Arthur M Krieg; Jean-Charles Cerottini; Pedro Romero
Rapid and strong human CD8+ T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909.
The Journal of clinical investigation 2005;115(3):739-46.
2005: Gabriel Bricard; Hanifa Bouzourene; Olivier Martinet; Donata Rimoldi; Nermin Halkic; Michel Gillet; Pascal Chaubert; H Robson MacDonald; Pedro Romero; Jean-Charles Cerottini; Daniel E Speiser
Naturally acquired MAGE-A10- and SSX-2-specific CD8+ T cell responses in patients with hepatocellular carcinoma.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(3):1709-16.
2004: Daniel E Speiser; Mikaël J Pittet; Philippe Guillaume; Norbert Lubenow; Eric Hoffman; Jean-Charles Cerottini; Pedro Romero
Ex vivo analysis of human antigen-specific CD8+ T-cell responses: quality assessment of fluorescent HLA-A2 multimer and interferon-gamma ELISPOT assays for patient immune monitoring.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2004;27(4):298-308.
2004: Danielle Liénard; Donata Rimoldi; Marie Marchand; Pierre-Yves Dietrich; Nicolas van Baren; Christine Geldhof; Pascal Batard; Philippe Guillaume; Maha Ayyoub; Mikaël J Pittet; Alfred Zippelius; Katharina Fleischhauer; Ferdy Lejeune; Jean-Charles Cerottini; Pedro Romero; Daniel E Speiser
Ex vivo detectable activation of Melan-A-specific T cells correlating with inflammatory skin reactions in melanoma patients vaccinated with peptides in IFA.
Cancer immunity 2004;4():4.
2004: Alfred Zippelius; Gilles Bioley; Frédérique-Anne Le Gal; Nathalie Rufer; Marlene Brandes; Pascal Batard; Magda De Smedt; Jean Plum; Daniel E Speiser; Jean-Charles Cerottini; Pierre-Yves Dietrich; Pedro Romero; Mikaël J Pittet
Human thymus exports naive CD8 T cells that can home to nonlymphoid tissues.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(5):2773-7.
2003: Daniel E Speiser; Mikaël J Pittet; Donata Rimoldi; Philippe Guillaume; Immanuel F Luescher; Danielle Liénard; Ferdy Lejeune; Jean-Charles Cerottini; Pedro Romero
Evaluation of melanoma vaccines with molecularly defined antigens by ex vivo monitoring of tumor-specific T cells.
Seminars in cancer biology 2003;13(6):461-72.
2003: Danila Valmori; Valérie Dutoit; Maha Ayyoub; Donata Rimoldi; Philippe Guillaume; Danielle Liénard; Ferdy Lejeune; Jean-Charles Cerottini; Pedro Romero; Daniel E Speiser
Simultaneous CD8+ T cell responses to multiple tumor antigen epitopes in a multipeptide melanoma vaccine.
Cancer immunity 2003;3():15.
2003: Daniel E Speiser; Donata Rimoldi; Pascal Batard; Danielle Liénard; Ferdy Lejeune; Jean-Charles Cerottini; Pedro Romero
Disease-driven T cell activation predicts immune responses to vaccination against melanoma.
Cancer immunity 2003;3():12.
2003: Maha Ayyoub; Alfred Zippelius; Mikaël J Pittet; Donata Rimoldi; Danila Valmori; Jean-Charles Cerottini; Pedro Romero; Ferdy Lejeune; Danielle Liénard; Daniel E Speiser
Activation of human melanoma reactive CD8+ T cells by vaccination with an immunogenic peptide analog derived from Melan-A/melanoma antigen recognized by T cells-1.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(2):669-77.
2002: Pedro Romero; Mikael Pittet; Valérie Dutoit; Alfred Zippelius; Danielle Liénard; Ferdy Lejeune; Philippe Guillaume; Donata Rimoldi; Danila Valmori; Daniel E Speiser; Jean-Charles Cerottini
Therapeutic cancer vaccines based on molecularly defined human tumor antigens.
Vaccine 2002;20 Suppl 4():A2-7.
2002: Daniel E Speiser; Jean-Charles Cerottini; Pedro Romero
Can hTERT peptide (540-548) -specific CD8 T cells recognize and kill tumor cells?
Cancer immunity 2002;2():14.
2002: Pedro Romero; Danila Valmori; Mikaël J Pittet; Alfred Zippelius; Donata Rimoldi; Frédéric Lévy; Valérie Dutoit; Maha Ayyoub; Verena Rubio-Godoy; Olivier Michielin; Philippe Guillaume; Pascal Batard; Immanuel F Luescher; Ferdy Lejeune; Danielle Liénard; Nathalie Rufer; Pierre-Yves Dietrich; Daniel E Speiser; Jean-Charles Cerottini
Antigenicity and immunogenicity of Melan-A/MART-1 derived peptides as targets for tumor reactive CTL in human melanoma.
Immunological reviews 2002;188():81-96.
2002: Mikaël J Pittet; Alfred Zippelius; Danila Valmori; Daniel E Speiser; Jean-Charles Cerottini; Pedro Romero
Melan-A/MART-1-specific CD8 T cells: from thymus to tumor.
Trends in immunology 2002;23(7):325-8.
2002: Daniel E Speiser; Danielle Liénard; Mikaël J Pittet; Pascal Batard; Donata Rimoldi; Philippe Guillaume; Jean-Charles Cerottini; Pedro Romero
In vivo activation of melanoma-specific CD8(+) T cells by endogenous tumor antigen and peptide vaccines. A comparison to virus-specific T cells.
European journal of immunology 2002;32(3):731-41.
2002: Alfred Zippelius; Mikaël J Pittet; Pascal Batard; Nathalie Rufer; Magda De Smedt; Philippe Guillaume; Kim Ellefsen; Danila Valmori; Danielle Liénard; Jean Plum; H Robson MacDonald; Daniel E Speiser; Jean-Charles Cerottini; Pedro Romero
Thymic selection generates a large T cell pool recognizing a self-peptide in humans.
The Journal of experimental medicine 2002;195(4):485-94.
2001: Daniel E Speiser; Marco COLONna; Maha Ayyoub; M Cella; Mikaël J Pittet; Pascal Batard; Danila Valmori; Philippe Guillaume; Danielle Liénard; Jean-Charles Cerottini; Pedro Romero
The activatory receptor 2B4 is expressed in vivo by human CD8+ effector alpha beta T cells.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(11):6165-70.
2001: Maha Ayyoub; M Migliaccio; Philippe Guillaume; Danielle Liénard; Jean-Charles Cerottini; Pedro Romero; Frédéric Lévy; Daniel E Speiser; Danila Valmori
Lack of tumor recognition by hTERT peptide 540-548-specific CD8(+) T cells from melanoma patients reveals inefficient antigen processing.
European journal of immunology 2001;31(9):2642-51.
2001: M J Pittet; Daniel E Speiser; D Valmori; D Rimoldi; Danielle Liénard; F Lejeune; J C Cerottini; P Romero
Ex vivo analysis of tumor antigen specific CD8+ T cell responses using MHC/peptide tetramers in cancer patients.
International immunopharmacology 2001;1(7):1235-47.
2001: Mikaël J Pittet; Alfred Zippelius; Daniel E Speiser; M Assenmacher; Philippe Guillaume; Danila Valmori; Danielle Liénard; Ferdy Lejeune; Jean-Charles Cerottini; Pedro Romero
Ex vivo IFN-gamma secretion by circulating CD8 T lymphocytes: implications of a novel approach for T cell monitoring in infectious and malignant diseases.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(12):7634-40.
2001: Mikaël J Pittet; Daniel E Speiser; Danielle Liénard; Danila Valmori; Philippe Guillaume; Valérie Dutoit; Donata Rimoldi; Ferdy Lejeune; Jean-Charles Cerottini; Pedro Romero
Expansion and functional maturation of human tumor antigen-specific CD8+ T cells after vaccination with antigenic peptide.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(3 Suppl):796s-803s.
2001: Daniel E Speiser; M Migliaccio; Mikaël J Pittet; Danila Valmori; Danielle Liénard; F Lejeune; Patrick Reichenbach; Philippe Guillaume; I Lüscher; Jean-Charles Cerottini; Pedro Romero
Human CD8(+) T cells expressing HLA-DR and CD28 show telomerase activity and are distinct from cytolytic effector T cells.
European journal of immunology 2001;31(2):459-66.
2000: Mikaël J Pittet; Daniel E Speiser; Danila Valmori; Jean-Charles Cerottini; Pedro Romero
Cutting edge: cytolytic effector function in human circulating CD8+ T cells closely correlates with CD56 surface expression.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(3):1148-52.
2000: P Romero; M J Pittet; D Valmori; Daniel E Speiser; V Cerundolo; Danielle Liénard; F Lejeune; J C Cerottini
Immune monitoring in cancer immunotherapy.
Ernst Schering Research Foundation workshop 2000;(30):75-97.
1999: Danila Valmori; Jean-François Fonteneau; Salvatore Valitutti; Nadine Gervois; R Dunbar; Danielle Liénard; Donata Rimoldi; Vincenzo Cerundolo; Francine Jotereau; Jean-Charles Cerottini; Daniel E Speiser; Pedro Romero
Optimal activation of tumor-reactive T cells by selected antigenic peptide analogues.
International immunology 1999;11(12):1971-80.
1999: Daniel E Speiser; Mikaël J Pittet; Danila Valmori; R Dunbar; Donata Rimoldi; Danielle Liénard; H Robson MacDonald; Jean-Charles Cerottini; Vincenzo Cerundolo; Pedro Romero
In vivo expression of natural killer cell inhibitory receptors by human melanoma-specific cytolytic T lymphocytes.
The Journal of experimental medicine 1999;190(6):775-82.
1999: Mikaël J Pittet; Danila Valmori; P R Dunbar; Daniel E Speiser; Danielle Liénard; Ferdy Lejeune; Katharina Fleischhauer; Vincenzo Cerundolo; Jean-Charles Cerottini; Pedro Romero
High frequencies of naive Melan-A/MART-1-specific CD8(+) T cells in a large proportion of human histocompatibility leukocyte antigen (HLA)-A2 individuals.
The Journal of experimental medicine 1999;190(5):705-15.
1999: Daniel E Speiser; Danila Valmori; Donata Rimoldi; Mikaël J Pittet; Danielle Liénard; Vincenzo Cerundolo; H Robson MacDonald; Jean-Charles Cerottini; Pedro Romero
CD28-negative cytolytic effector T cells frequently express NK receptors and are present at variable proportions in circulating lymphocytes from healthy donors and melanoma patients.
European journal of immunology 1999;29(6):1990-9.