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Ewoud Speksnijder

Research Profile

Living Beings

Chemicals & Drugs

Genes & Molecular Sequences

Genes, p53

Disorders

Anatomy

Phenomena

Physiology

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Publications

TOP 3
Joost P M Melis; Joke Robinson; Daniela C F Salvatori; Mirjam M Schaap; Ewoud N Speksnijder; Jan van Benthem; Raoul V Kuiper; Mirjam Luijten; Saskia Maas; Aart Verhoef; Harry van Steeg
Detection of genotoxic and non-genotoxic carcinogens in Xpc(-/-)p53(+/-) mice.
Karin E de Visser; Cheei-Sing Hau; Nick Barker; Metamia Ciampricotti; Hans Clevers; Ewa M Michalak; Ewoud N Speksnijder; David Wei-Min Tan; Jos Jonkers
Developmental stage-specific contribution of LGR5(+) cells to basal and luminal epithelial lineages in the postnatal mammary gland.
Metamia Ciampricotti; Kim Vrijland; Cheei-Sing Hau; Tea Pemovska; Chris W Doornebal; Ewoud N Speksnijder; Katharina Wartha; Jos Jonkers; Karin E de Visser
Development of metastatic HER2(+) breast cancer is independent of the adaptive immune system.

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All Publications

2013: Joost P M Melis; Joke Robinson; Daniela C F Salvatori; Mirjam M Schaap; Ewoud N Speksnijder; Jan van Benthem; Raoul V Kuiper; Mirjam Luijten; Saskia Maas; Aart Verhoef; Harry van Steeg
Detection of genotoxic and non-genotoxic carcinogens in Xpc(-/-)p53(+/-) mice.
Toxicology and applied pharmacology 2013;266(2):289-97.
2012: Karin E de Visser; Cheei-Sing Hau; Nick Barker; Metamia Ciampricotti; Hans Clevers; Ewa M Michalak; Ewoud N Speksnijder; David Wei-Min Tan; Jos Jonkers
Developmental stage-specific contribution of LGR5(+) cells to basal and luminal epithelial lineages in the postnatal mammary gland.
The Journal of pathology 2012;228(3):300-9.
2011: Metamia Ciampricotti; Kim Vrijland; Cheei-Sing Hau; Tea Pemovska; Chris W Doornebal; Ewoud N Speksnijder; Katharina Wartha; Jos Jonkers; Karin E de Visser
Development of metastatic HER2(+) breast cancer is independent of the adaptive immune system.
The Journal of pathology 2011;224(1):56-66.
2010: Bastiaan Evers; Ewoud N Speksnijder; Eva Schut; Metamia Ciampricotti; Matthew J Smalley; Patrick W B Derksen; Jos Jonkers; Karin E de Visser
A tissue reconstitution model to study cancer cell-intrinsic and -extrinsic factors in mammary tumourigenesis.
The Journal of pathology 2010;220(1):34-44.
2007: Joanne G W Nijhof; Aat M Mulder; Ewoud N Speksnijder; Esther M Hoogervorst; Leon H F Mullenders; Frank R de Gruijl
Growth stimulation of UV-induced DNA damage retaining epidermal basal cells gives rise to clusters of p53 overexpressing cells.
DNA repair 2007;6(11):1642-50.
2007: Susan W P Wijnhoven; Ewoud N Speksnijder; Xiaoling Liu; Edwin Zwart; Conny Th M vanOostrom; Rudolf B Beems; Esther M Hoogervorst; Mirjam M Schaap; Laura D Attardi; Tyler Jacks; Harry van Steeg; Jos Jonkers; Annemieke de Vries
Dominant-negative but not gain-of-function effects of a p53.R270H mutation in mouse epithelium tissue after DNA damage.
Cancer research 2007;67(10):4648-56.
2006: Mirjam Luijten; Ewoud N Speksnijder; Niels van Alphen; Anja Westerman; Siem H Heisterkamp; Jan van Benthem; Coen F van Kreijl; Rudolf B Beems; Harry van Steeg
Phenacetin acts as a weak genotoxic compound preferentially in the kidney of DNA repair deficient Xpa mice.
Mutation research 2006;596(1-2):143-50.
2005: Susan W P Wijnhoven; Edwin Zwart; Ewoud N Speksnijder; Rudolf B Beems; Kenneth P Olive; David A Tuveson; Jos Jonkers; Mirjam M Schaap; Jolanda van den Berg; Tyler Jacks; Harry van Steeg; Annemieke de Vries
Mice expressing a mammary gland-specific R270H mutation in the p53 tumor suppressor gene mimic human breast cancer development.
Cancer research 2005;65(18):8166-73.