FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Kevin Spencer

Research Profile

Physiology

Chemicals & Drugs

Disorders

Concepts & Ideas

Procedures

Anatomy

Phenomena

False Positive Reactions

Co-author Network

Publications

TOP 3
Kevin Spencer; Nicholas J Cowans
Accuracy of self-reported smoking status in first trimester aneuploidy screening.
Nicholas J Cowans; Kevin Spencer
First trimester maternal serum inhibin A concentrations in smokers.
Kevin Spencer; Nicholas J Cowans
Analytical goal setting in aneuploidy screening: within person biological variability of first trimester biochemical markers.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Kevin Spencer (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Kevin Spencer; Nicholas J Cowans
Accuracy of self-reported smoking status in first trimester aneuploidy screening.
Prenatal diagnosis 2013;33(3):245-50.
2013: Nicholas J Cowans; Kevin Spencer
First trimester maternal serum inhibin A concentrations in smokers.
Prenatal diagnosis 2013;33(3):296-7.
2013: Kevin Spencer; Nicholas J Cowans
Analytical goal setting in aneuploidy screening: within person biological variability of first trimester biochemical markers.
Prenatal diagnosis 2013;33(2):124-9.
2013: Kevin Spencer; Nicholas J Cowans
Correction of first trimester biochemical aneuploidy screening markers for smoking status: influence of gestational age, maternal ethnicity and cigarette dosage.
Prenatal diagnosis 2013;33(2):116-23.
2013: Nicholas J Cowans; Kevin Spencer
Effect of gestational age on first trimester maternal serum prenatal screening correction factors for ethnicity and IVF conception.
Prenatal diagnosis 2013;33(1):56-60.
2012: F Akinlade; Nicholas J Cowans; M C Kisanga; Kevin Spencer
Maternal serum CA 19-9 and CA 15-3 levels in pregnancies affected by trisomy 21.
Prenatal diagnosis 2012;32(7):644-8.
2012: Nicholas J Cowans; M C Kisanga; Kevin Spencer
Maternal serum placental growth factor in second trimester trisomy 21 pregnancies.
Prenatal diagnosis 2012;32(2):117-21.
2012: Nicholas J Cowans; A Khan; M Kisanga; Kevin Spencer
A comparison of two immunoassay methods for the measurement of maternal serum placental growth factor in early pregnancy.
Fetal diagnosis and therapy 2012;31(4):254-9.
2011: Nicholas J Cowans; H Alfthan; U H Stenman; Kevin Spencer
Stability of first trimester placental growth factor in serum and whole blood.
Prenatal diagnosis 2011;31(12):1193-7.
2011: Nicholas J Cowans; Kevin Spencer
The relationship between maternal body mass, smoking status and ethnicity and first trimester nuchal translucency thickness.
Prenatal diagnosis 2011;31(5):446-9.
2011: Nicholas J Cowans; Anastasia Stamatopoulou; Niels Tørring; Kevin Spencer
Early first-trimester maternal serum placental growth factor in trisomy 21 pregnancies.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2011;37(5):515-9.
2011: Nicholas J Cowans; Anastasia Stamatopoulou; Paivi Liitti; Mikko Suonpaa; Kevin Spencer
The stability of free-β human chorionic gonadotrophin and pregnancy-associated plasma protein-A in first trimester dried blood spots.
Prenatal diagnosis 2011;31(3):293-8.
2011: Nicholas J Cowans; Anastasia Stamatopoulou; A Khalil; Kevin Spencer
PP13 as a marker of pre-eclampsia: A two platform comparison study.
Placenta 2011;32 Suppl():S37-41.
2011: Kevin Spencer
First and second trimester markers of fetal aneuploidy in pregnant women with HIV infection.
Fetal diagnosis and therapy 2011;29(2):135-8.
2011: Anastasia Stamatopoulou; Constantin S von Kaisenberg; Nicholas J Cowans; Elisabet Matwejew; Kevin Spencer
Placental protein-13 and pregnancy-associated plasma protein-A as first trimester screening markers for hypertensive disorders and small for gestational age outcomes.
Hypertension in pregnancy : official journal of the International Society for the Study of Hypertension in Pregnancy 2011;30(4):384-95.
2010: Kevin Spencer; Nicholas J Cowans; C E Spencer; N Achillea
A re-evaluation of the influence of maternal insulin-dependent diabetes on fetal nuchal translucency thickness and first-trimester maternal serum biochemical markers of aneuploidy.
Prenatal diagnosis 2010;30(10):937-40.
2010: Nicholas J Cowans; Anastasia Stamatopoulou; S Jaakohuhta; S Hentunen; Kevin Spencer
PP13 stability in first trimester maternal serum and whole blood.
Prenatal diagnosis 2010;30(6):582-5.
2010: Nicholas J Cowans; Anastasia Stamatopoulou; E Matwejew; Constantin S von Kaisenberg; Kevin Spencer
First-trimester placental growth factor as a marker for hypertensive disorders and SGA.
Prenatal diagnosis 2010;30(6):565-70.
2010: Nicholas J Cowans; Anastasia Stamatopoulou; S Jaakohuhta; Kevin Spencer
ADAM-12 stability in first trimester maternal serum.
Prenatal diagnosis 2010;30(6):555-60.
2010: Kevin Spencer; C E Spencer; Anastasia Stamatopoulou; Ismini Staboulidou; Kypros H Nicolaides
Early vaginal bleeding has no impact on markers used in first trimester aneuploidy screening.
Prenatal diagnosis 2010;30(6):547-50.
2010: Nicholas J Cowans; Anastasia Stamatopoulou; Kevin Spencer
First trimester maternal serum placental growth factor in trisomy 21 pregnancies.
Prenatal diagnosis 2010;30(5):449-53.
2010: Kevin Spencer; Ismini Staboulidou; Kypros H Nicolaides
First trimester aneuploidy screening in the presence of a vanishing twin: implications for maternal serum markers.
Prenatal diagnosis 2010;30(3):235-40.
2010: Pierre Miron; Jean Lambert; Anne Marcil; Nicholas J Cowans; Anastasia Stamatopoulou; Kevin Spencer
Maternal plasma levels of follistatin-related gene protein in the first trimester of pregnancies with Down syndrome.
Prenatal diagnosis 2010;30(3):224-8.
2010: Nicholas J Cowans; Anastasia Stamatopoulou; Johanna Hellström; Minna-Maarit Mäkelä; Kevin Spencer
PAPP-A and free ss-hCG stability in first trimester serum using PerkinElmer AutoDELFIA and DELFIA Xpress systems.
Prenatal diagnosis 2010;30(2):127-32.
2009: Kevin Spencer; Ismini Staboulidou; Jader De Jesus Cruz; George Karagiannis; Kypros H Nicolaides
Maternal serum screening marker levels in women with a previous aneuploidy pregnancy.
Prenatal diagnosis 2009;29(13):1242-3.
2009: Kevin Spencer; Osasumwen Enofe; Nicholas J Cowans; Anastasia Stamatopoulou
Is maternal renal disease a cause of elevated free beta-hCG in first trimester aneuploidy screening?
Prenatal diagnosis 2009;29(11):1045-9.
2009: Nicholas J Cowans; Anastasia Stamatopoulou; Nerea Maiz; Kevin Spencer; Kypros H Nicolaides
The impact of fetal gender on first trimester nuchal translucency and maternal serum free beta-hCG and PAPP-A MoM in normal and trisomy 21 pregnancies.
Prenatal diagnosis 2009;29(6):578-81.
2009: Nicholas J Cowans; Anastasia Stamatopoulou; Kevin Spencer
The effect of Rhesus status on first-trimester pregnancy screening markers free beta human chorionic gonadotropin, pregnancy-associated plasma protein-A and nuchal translucency.
Prenatal diagnosis 2009;29(5):505-7.
2008: Kevin Spencer; Nicholas J Cowans; Niels Uldbjerg; Annie Vereecken; Niels Tørring
First trimester intact hCG as an early marker of trisomy 21: a promise unrecognised?
Prenatal diagnosis 2008;28(12):1156-9.
2008: Kevin Spencer; Nicholas J Cowans; Kypros H Nicolaides
Maternal serum inhibin-A and activin-A levels in the first trimester of pregnancies developing pre-eclampsia.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2008;32(5):622-6.
2008: Karl Oliver Kagan; Dave Wright; Kevin Spencer; Francisca S Molina; Kypros H Nicolaides
First-trimester screening for trisomy 21 by free beta-human chorionic gonadotropin and pregnancy-associated plasma protein-A: impact of maternal and pregnancy characteristics.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2008;31(5):493-502.
2008: Kevin Spencer; Nicholas J Cowans; Anastasia Stamatopoulou
Maternal serum ADAM12s in the late first trimester of pregnancies with Trisomy 21.
Prenatal diagnosis 2008;28(5):422-4.
2008: Kevin Spencer; Nicholas J Cowans; Niels Uldbjerg; Niels Tørring
First-trimester ADAM12s as early markers of trisomy 21: a promise still unfulfilled?
Prenatal diagnosis 2008;28(4):338-42.
2008: Kevin Spencer; Nicholas J Cowans; Anastasia Stamatopoulou
ADAM12s in maternal serum as a potential marker of pre-eclampsia.
Prenatal diagnosis 2008;28(3):212-6.
2008: George Makrydimas; Alexandros Sotiriadis; Makrina D Savvidou; Kevin Spencer; Kypros H Nicolaides
Physiological distribution of placental growth factor and soluble Flt-1 in early pregnancy.
Prenatal diagnosis 2008;28(3):175-9.
2008: Kevin Spencer; Annie Vereecken; Nicholas J Cowans
Maternal serum ADAM12s as a potential marker of trisomy 21 prior to 10 weeks of gestation.
Prenatal diagnosis 2008;28(3):209-11.
2008: Nicholas J Cowans; Kevin Spencer; Hamutal Meiri
First-trimester maternal placental protein 13 levels in pregnancies resulting in adverse outcomes.
Prenatal diagnosis 2008;28(2):121-5.
2008: Kevin Spencer; Nicholas J Cowans; F Molina; K O Kagan; Kypros H Nicolaides
First-trimester ultrasound and biochemical markers of aneuploidy and the prediction of preterm or early preterm delivery.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2008;31(2):147-52.
2008: Kevin Spencer; Karl O Kagan; Kypros H Nicolaides
Screening for trisomy 21 in twin pregnancies in the first trimester: an update of the impact of chorionicity on maternal serum markers.
Prenatal diagnosis 2008;28(1):49-52.
2008: Kevin Spencer; Nicholas J Cowans; Kypros H Nicolaides
Low levels of maternal serum PAPP-A in the first trimester and the risk of pre-eclampsia.
Prenatal diagnosis 2008;28(1):7-10.
2008: Kevin Spencer; Nicholas J Cowans; K Avgidou; F Molina; Kypros H Nicolaides
First-trimester biochemical markers of aneuploidy and the prediction of small-for-gestational age fetuses.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2008;31(1):15-9.
2007: Kevin Spencer; Nicholas J Cowans; Anastasia Stamatopoulou
Maternal serum ADAM12s as a marker of rare aneuploidies in the first or second trimester of pregnancy.
Prenatal diagnosis 2007;27(13):1233-7.
2007: Kevin Spencer; Nicholas J Cowans
ADAM12 as a marker of trisomy 18 in the first and second trimester of pregnancy.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2007;20(9):645-50.
2007: Karl Oliver Kagan; Veronika Frisova; Kypros H Nicolaides; Kevin Spencer
Dose dependency between cigarette consumption and reduced maternal serum PAPP-A levels at 11-13+6 weeks of gestation.
Prenatal diagnosis 2007;27(9):849-53.
2007: Michael Christiansen; Kevin Spencer; Jennie Laigaard; Nicholas J Cowans; Severin Olesen Larsen; Ulla M Wewer
ADAM 12 as a second-trimester maternal serum marker in screening for Down syndrome.
Prenatal diagnosis 2007;27(7):611-5.
2007: Nicholas J Cowans; Kevin Spencer
First-trimester ADAM12 and PAPP-A as markers for intrauterine fetal growth restriction through their roles in the insulin-like growth factor system.
Prenatal diagnosis 2007;27(3):264-71.
2007: Kevin Spencer; Nicholas J Cowans; Ilana Chefetz; Joseph Tal; Ido Kuhnreich; Hamutal Meiri
Second-trimester uterine artery Doppler pulsatility index and maternal serum PP13 as markers of pre-eclampsia.
Prenatal diagnosis 2007;27(3):258-63.
2007: Kevin Spencer
Aneuploidy screening in the first trimester.
American journal of medical genetics. Part C, Seminars in medical genetics 2007;145C(1):18-32.
2007: Kevin Spencer; Nicholas J Cowans; Ilana Chefetz; Joseph Tal; Hamutal Meiri
First-trimester maternal serum PP-13, PAPP-A and second-trimester uterine artery Doppler pulsatility index as markers of pre-eclampsia.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2007;29(2):128-34.
2007: Nicholas J Cowans; Kevin Spencer
Is there an association between maternal ABO and rhesus blood groups and the first-trimester serum markers free beta-hCG and PAPP-A used for the detection of fetal aneuploidy?
Prenatal diagnosis 2007;27(1):64-7.
2006: George Makrydimas; Alexandros Sotiriadis; Kevin Spencer; Nicholas J Cowans; Kypros H Nicolaides
ADAM12-s in coelomic fluid and maternal serum in early pregnancy.
Prenatal diagnosis 2006;26(13):1197-200.
2006: Kevin Spencer; Nicholas J Cowans; K Avgidou; Kypros H Nicolaides
First-trimester ultrasound and biochemical markers of aneuploidy and the prediction of impending fetal death.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2006;28(5):637-43.
2006: Jennie Laigaard; Kevin Spencer; Michael Christiansen; Nicholas J Cowans; Severin Olesen Larsen; Bent Nørgaard Pedersen; Ulla M Wewer
ADAM 12 as a first-trimester maternal serum marker in screening for Down syndrome.
Prenatal diagnosis 2006;26(10):973-9.
2006: Kevin Spencer; C K H Yu; Makrina D Savvidou; Aris T Papageorghiou; Kypros H Nicolaides
Prediction of pre-eclampsia by uterine artery Doppler ultrasonography and maternal serum pregnancy-associated plasma protein-A, free beta-human chorionic gonadotropin, activin A and inhibin A at 22 + 0 to 24 + 6 weeks' gestation.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2006;27(6):658-63.
2006: Aris T Papageorghiou; Kyriaki Avgidou; Kevin Spencer; Barry Nix; Kypros H Nicolaides
Sonographic screening for trisomy 13 at 11 to 13(+6) weeks of gestation.
American journal of obstetrics and gynecology 2006;194(2):397-401.
2006: Orlando Falcon; M Auer; A Gerovassili; Kevin Spencer; Kypros H Nicolaides
Screening for trisomy 21 by fetal tricuspid regurgitation, nuchal translucency and maternal serum free beta-hCG and PAPP-A at 11 + 0 to 13 + 6 weeks.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2006;27(2):151-5.
2005: Simona Cicero; Kevin Spencer; Kyriaki Avgidou; Stefano Faiola; Kypros H Nicolaides
Maternal serum biochemistry at 11-13(+6) weeks in relation to the presence or absence of the fetal nasal bone on ultrasonography in chromosomally abnormal fetuses: an updated analysis of integrated ultrasound and biochemical screening.
Prenatal diagnosis 2005;25(11):977-83.
2005: Kevin Spencer; Simona Cicero; Alessia Atzei; Chineze Otigbah; Kypros H Nicolaides
The influence of maternal insulin-dependent diabetes on fetal nuchal translucency thickness and first-trimester maternal serum biochemical markers of aneuploidy.
Prenatal diagnosis 2005;25(10):927-9.
2005: Kevin Spencer; C K H Yu; Nicholas J Cowans; Chineze Otigbah; Kypros H Nicolaides
Prediction of pregnancy complications by first-trimester maternal serum PAPP-A and free beta-hCG and with second-trimester uterine artery Doppler.
Prenatal diagnosis 2005;25(10):949-53.
2005: George Makrydimas; H Vandecruys; Alexandros Sotiriadis; L Lakasing; Kevin Spencer; Kypros H Nicolaides
Coelomic fluid leptin concentration in normal first-trimester pregnancies and missed miscarriages.
Fetal diagnosis and therapy 2005;20(5):406-9.
2005: Nicholas J Cowans; Kevin Spencer
First and second-trimester biochemical markers of chromosomal anomalies and their relationship to maternal haemoglobin levels.
Prenatal diagnosis 2005;25(8):693-9.
2005: Kyriaki Avgidou; Aris T Papageorghiou; Renu Bindra; Kevin Spencer; Kypros H Nicolaides
Prospective first-trimester screening for trisomy 21 in 30,564 pregnancies.
American journal of obstetrics and gynecology 2005;192(6):1761-7.
2005: Kevin Spencer; V Heath; A El-Sheikhah; C Y T Ong; Kypros H Nicolaides
Ethnicity and the need for correction of biochemical and ultrasound markers of chromosomal anomalies in the first trimester: a study of Oriental, Asian and Afro-Caribbean populations.
Prenatal diagnosis 2005;25(5):365-9.
2005: Kevin Spencer; Jennifer A Crossley; David A Aitken; Kypros H Nicolaides
Second-trimester levels of pregnancy-associated plasma protein-A and free beta-hCG in pregnancies with trisomy 13.
Prenatal diagnosis 2005;25(5):358-61.
2005: Kypros H Nicolaides; Kevin Spencer; Kyriaki Avgidou; Stefano Faiola; Orlando Falcon
Multicenter study of first-trimester screening for trisomy 21 in 75 821 pregnancies: results and estimation of the potential impact of individual risk-orientated two-stage first-trimester screening.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2005;25(3):221-6.
2005: Kevin Spencer; C K H Yu; Georgios Rembouskos; Renu Bindra; Kypros H Nicolaides
First trimester sex hormone-binding globulin and subsequent development of preeclampsia or other adverse pregnancy outcomes.
Hypertension in pregnancy : official journal of the International Society for the Study of Hypertension in Pregnancy 2005;24(3):303-11.
2005: Subhasis Banerjee; Alan Smallwood; Anne E Chambers; Aris T Papageorghiou; Hugues Loosfelt; Kevin Spencer; Stuart Campbell; Kypros Nicolaides
A link between high serum levels of human chorionic gonadotrophin and chorionic expression of its mature functional receptor (LHCGR) in Down's syndrome pregnancies.
Reproductive biology and endocrinology : RB&E 2005;3():25.
2005: Kevin Spencer
First trimester maternal serum screening for Down's syndrome: an evaluation of the DPC Immulite 2000 free beta-hCG and pregnancy-associated plasma protein-A assays.
Annals of clinical biochemistry 2005;42(Pt 1):30-40.
2004: Kevin Spencer; D Aitken
Factors affecting women's preference for type of prenatal screening test for chromosomal anomalies.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2004;24(7):735-9.
2004: K H Nicolaides; Victoria Heath; Kevin Spencer; A B J Nix
Nuchal translucency and gestational age.
Prenatal diagnosis 2004;24(10):833-4; author reply 834-5.
2004: C K H Yu; Aris T Papageorghiou; Renu Bindra; Kevin Spencer; Kypros H Nicolaides
Second-trimester sex hormone-binding globulin and subsequent development of pre-eclampsia.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2004;16(3):158-62.
2004: C K H Yu; L Lakasing; Aris T Papageorghiou; Kevin Spencer; Kypros H Nicolaides
Uterine artery Doppler and mid-trimester maternal plasma homocysteine in subsequent pre-eclampsia.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2004;16(2):134-9.
2004: C Y T Ong; AW Liao; S Munim; Kevin Spencer; Kypros H Nicolaides
First-trimester maternal serum activin A in pre-eclampsia and fetal growth restriction.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2004;15(3):176-80.
2004: Kevin Spencer; Renu Bindra; Anna Maria Cacho; Kypros H Nicolaides
The impact of correcting for smoking status when screening for chromosomal anomalies using maternal serum biochemistry and fetal nuchal translucency thickness in the first trimester of pregnancy.
Prenatal diagnosis 2004;24(3):169-73.
2003: Kevin Spencer; Renu Bindra; Kypros H Nicolaides
Maternal weight correction of maternal serum PAPP-A and free beta-hCG MoM when screening for trisomy 21 in the first trimester of pregnancy.
Prenatal diagnosis 2003;23(10):851-5.
2003: Kevin Spencer; Renu Bindra; A B J Nix; Victoria Heath; Kypros H Nicolaides
Delta-NT or NT MoM: which is the most appropriate method for calculating accurate patient-specific risks for trisomy 21 in the first trimester?
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2003;22(2):142-8.
2003: Kevin Spencer; Jacques B de Kok; D W Swinkels
Increased total cell-free DNA in the serum of pregnant women carrying a fetus affected by trisomy 21.
Prenatal diagnosis 2003;23(7):580-3.
2003: Kevin Spencer; Jennifer A Crossley; David A Aitken; A B J Nix; Frank Dunstan; K Williams
The effect of temporal variation in biochemical markers of trisomy 21 across the first and second trimesters of pregnancy on the estimation of individual patient-specific risks and detection rates for Down's syndrome.
Annals of clinical biochemistry 2003;40(Pt 3):219-31.
2003: Simona Cicero; Renu Bindra; Georgios Rembouskos; Kevin Spencer; Kypros H Nicolaides
Integrated ultrasound and biochemical screening for trisomy 21 using fetal nuchal translucency, absent fetal nasal bone, free beta-hCG and PAPP-A at 11 to 14 weeks.
Prenatal diagnosis 2003;23(4):306-10.
2003: Kevin Spencer
The influence of different sample collection types on the levels of markers used for Down's syndrome screening as measured by the Kryptor Immunosassay system.
Annals of clinical biochemistry 2003;40(Pt 2):166-8.
2003: Kevin Spencer; Christine E Spencer; Maureen Power; Carolynne Dawson; Kypros H Nicolaides
Screening for chromosomal abnormalities in the first trimester using ultrasound and maternal serum biochemistry in a one-stop clinic: a review of three years prospective experience.
BJOG : an international journal of obstetrics and gynaecology 2003;110(3):281-6.
2003: Kevin Spencer; Kypros H Nicolaides
Screening for trisomy 21 in twins using first trimester ultrasound and maternal serum biochemistry in a one-stop clinic: a review of three years experience.
BJOG : an international journal of obstetrics and gynaecology 2003;110(3):276-80.
2003: JA Talbot; Kevin Spencer; RA Abushoufa
Detection of maternal serum hCG glycoform variants in the second trimester of pregnancies affected by Down syndrome using a lectin immunoassay.
Prenatal diagnosis 2003;23(1):1-5.
2002: Kevin Spencer
Uptake of prenatal screening for chromosomal anomalies: impact of test results in a previous pregnancy.
Prenatal diagnosis 2002;22(13):1229-32.
2002: Kevin Spencer; Jennifer A Crossley; David A Aitken; A B J Nix; Frank Dunstan; K Williams
Temporal changes in maternal serum biochemical markers of trisomy 21 across the first and second trimester of pregnancy.
Annals of clinical biochemistry 2002;39(Pt 6):567-76.
2002: Kevin Spencer; Howard Cuckle
Screening for chromosomal anomalies in the first trimester: does repeat maternal serum screening improve detection rates?
Prenatal diagnosis 2002;22(10):903-6.
2002: Kevin Spencer; Kypros H Nicolaides
A first trimester trisomy 13/trisomy 18 risk algorithm combining fetal nuchal translucency thickness, maternal serum free beta-hCG and PAPP-A.
Prenatal diagnosis 2002;22(10):877-9.
2002: Kevin Spencer
Between pregnancy biological variability of first trimester markers of Down syndrome and the implications for screening in subsequent pregnancies: an issue revisited.
Prenatal diagnosis 2002;22(10):874-6.
2002: Renu Bindra; Victoria Heath; AW Liao; Kevin Spencer; Kypros H Nicolaides
One-stop clinic for assessment of risk for trisomy 21 at 11-14 weeks: a prospective study of 15 030 pregnancies.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2002;20(3):219-25.
2002: Kevin Spencer; JA Talbot; RA Abushoufa
Maternal serum hyperglycosylated human chorionic gonadotrophin (HhCG) in the first trimester of pregnancies affected by Down syndrome, using a sialic acid-specific lectin immunoassay.
Prenatal diagnosis 2002;22(8):656-62.
2001: Kevin Spencer
Age related detection and false positive rates when screening for Down's syndrome in the first trimester using fetal nuchal translucency and maternal serum free betahCG and PAPP-A.
BJOG : an international journal of obstetrics and gynaecology 2001;108(10):1043-6.
2001: C Y T Ong; AW Liao; Ana Maria Cacho; Kevin Spencer; Kypros H Nicolaides
First-trimester maternal serum levels of placenta growth factor as predictor of preeclampsia and fetal growth restriction.
Obstetrics and gynecology 2001;98(4):608-11.
2001: Kevin Spencer; AW Liao; C Y T Ong; Lut Geerts; Kypros H Nicolaides
First trimester maternal serum placenta growth factor (PIGF)concentrations in pregnancies with fetal trisomy 21 or trisomy 18.
Prenatal diagnosis 2001;21(9):718-22.
2001: Kevin Spencer
Screening for trisomy 21 in twin pregnancies in the first trimester: does chorionicity impact on maternal serum free beta-hCG or PAPP-A levels?
Prenatal diagnosis 2001;21(9):715-7.
2001: Kevin Spencer; AW Liao; C Y T Ong; N J Flack; Kypros H Nicolaides
Maternal serum activin A and inhibin A in trisomy 18 pregnancies at 10-14 weeks.
Prenatal diagnosis 2001;21(7):571-4.
2001: AW Liao; Victoria Heath; Nikos A Kametas; Kevin Spencer; Kypros H Nicolaides
First-trimester screening for trisomy 21 in singleton pregnancies achieved by assisted reproduction.
Human reproduction (Oxford, England) 2001;16(7):1501-4.
2001: Kevin Spencer
Between pregnancy biological variability of first trimester markers of Down syndrome: implications for screening in subsequent pregnancies.
Prenatal diagnosis 2001;21(6):445-7.
2001: Kevin Spencer; AW Liao; C Y T Ong; Lut Geerts; Kypros H Nicolaides
Maternal serum levels of dimeric inhibin A in pregnancies affected by trisomy 21 in the first trimester.
Prenatal diagnosis 2001;21(6):441-4.
2001: Kevin Spencer; AW Liao; H Skentou; C Y T Ong; Kypros H Nicolaides
Maternal serum levels of total activin-A in first-trimester trisomy 21 pregnancies.
Prenatal diagnosis 2001;21(4):270-3.
2000: AW Liao; Rosalinde Snijders; Lut Geerts; Kevin Spencer; Kypros H Nicolaides
Fetal heart rate in chromosomally abnormal fetuses.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2000;16(7):610-3.
2000: Kevin Spencer; C Y T Ong; AW Liao; D Papademetriou; Kypros H Nicolaides
First trimester markers of trisomy 21 and the influence of maternal cigarette smoking status.
Prenatal diagnosis 2000;20(10):852-3.
2000: Kevin Spencer; C Y T Ong; AW Liao; Kypros H Nicolaides
The influence of parity and gravidity on first trimester markers of chromosomal abnormality.
Prenatal diagnosis 2000;20(10):792-4.
2000: Kevin Spencer; C E Spencer; M Power; A Moakes; Kypros H Nicolaides
One stop clinic for assessment of risk for fetal anomalies: a report of the first year of prospective screening for chromosomal anomalies in the first trimester.
BJOG : an international journal of obstetrics and gynaecology 2000;107(10):1271-5.
2000: C Y T Ong; AW Liao; Kevin Spencer; S Munim; Kypros H Nicolaides
First trimester maternal serum free beta human chorionic gonadotrophin and pregnancy associated plasma protein A as predictors of pregnancy complications.
BJOG : an international journal of obstetrics and gynaecology 2000;107(10):1265-70.
2000: Kevin Spencer; C Y T Ong; AW Liao; D Papademetriou; Kypros H Nicolaides
The influence of fetal sex in screening for trisomy 21 by fetal nuchal translucency, maternal serum free beta-hCG and PAPP-A at 10-14 weeks of gestation.
Prenatal diagnosis 2000;20(8):673-5.
2000: Kevin Spencer
Second-trimester prenatal screening for Down syndrome and the relationship of maternal serum biochemical markers to pregnancy complications with adverse outcome.
Prenatal diagnosis 2000;20(8):652-6.
2000: Kevin Spencer
The influence of fetal sex in screening for Down syndrome in the second trimester using AFP and free beta-hCG.
Prenatal diagnosis 2000;20(8):648-51.
2000: Kevin Spencer; V Heath; N Flack; C Ong; Kypros H Nicolaides
First trimester maternal serum AFP and total hCG in aneuploidies other than trisomy 21.
Prenatal diagnosis 2000;20(8):635-9.
2000: Kevin Spencer; AW Liao; H Skentou; Simona Cicero; Kypros H Nicolaides
Screening for triploidy by fetal nuchal translucency and maternal serum free beta-hCG and PAPP-A at 10-14 weeks of gestation.
Prenatal diagnosis 2000;20(6):495-9.
2000: Kevin Spencer; C Y T Ong; AW Liao; Kypros H Nicolaides
The influence of ethnic origin on first trimester biochemical markers of chromosomal abnormalities.
Prenatal diagnosis 2000;20(6):491-4.
2000: Kevin Spencer; C Ong; H Skentou; AW Liao; K H Nicolaides
Screening for trisomy 13 by fetal nuchal translucency and maternal serum free beta-hCG and PAPP-A at 10-14 weeks of gestation.
Prenatal diagnosis 2000;20(5):411-6.
2000: Kevin Spencer; N Tul; Kypros H Nicolaides
Maternal serum free beta-hCG and PAPP-A in fetal sex chromosome defects in the first trimester.
Prenatal diagnosis 2000;20(5):390-4.
2000: Kevin Spencer; E Berry; Jennifer A Crossley; David A Aitken; Kypros H Nicolaides
Is maternal serum total hCG a marker of trisomy 21 in the first trimester of pregnancy?
Prenatal diagnosis 2000;20(4):311-7.
2000: Kevin Spencer
Screening for trisomy 21 in twin pregnancies in the first trimester using free beta-hCG and PAPP-A, combined with fetal nuchal translucency thickness.
Prenatal diagnosis 2000;20(2):91-5.
1999: Kevin Spencer
Second trimester prenatal screening for Down's syndrome using alpha-fetoprotein and free beta hCG: a seven year review.
British journal of obstetrics and gynaecology 1999;106(12):1287-93.
1999: Kevin Spencer
The influence of smoking on maternal serum PAPP-A and free beta hCG levels in the first trimester of pregnancy.
Prenatal diagnosis 1999;19(11):1065-6.
1999: Kevin Spencer; V Souter; N Tul; Rosalinde Snijders; Kypros H Nicolaides
A screening program for trisomy 21 at 10-14 weeks using fetal nuchal translucency, maternal serum free beta-human chorionic gonadotropin and pregnancy-associated plasma protein-A.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 1999;13(4):231-7.
1999: Kevin Spencer
Accuracy of Down's syndrome risks produced in a prenatal screening program.
Annals of clinical biochemistry 1999;36 ( Pt 1)():101-3.
1998: Kevin Spencer; P Carpenter
Is prostate-specific antigen a marker for pregnancies affected by Down syndrome?
Clinical chemistry 1998;44(11):2362-5.
1998: Kevin Spencer
The influence of smoking on maternal serum AFP and free beta hCG levels and the impact on screening for Down syndrome.
Prenatal diagnosis 1998;18(3):225-34.
1997: Kevin Spencer; F Muller; David A Aitken
Amniotic fluid and maternal serum levels of CA125 in pregnancies affected by Down syndrome: a re-evaluation of the role of CA125 in Down syndrome screening.
Prenatal diagnosis 1997;17(8):701-6.
1997: NJ Sebire; Kevin Spencer; PL Noble; K Hughes; Kypros H Nicolaides
Maternal serum alpha-fetoprotein in fetal neural tube and abdominal wall defects at 10 to 14 weeks of gestation.
British journal of obstetrics and gynaecology 1997;104(7):849-51.
1997: Kevin Spencer; P Noble; Rosalinde Snijders; Kypros H Nicolaides
First-trimester urine free beta hCG, beta core, and total oestriol in pregnancies affected by Down's syndrome: implications for first-trimester screening with nuchal translucency and serum free beta hCG.
Prenatal diagnosis 1997;17(6):525-38.
1997: Kevin Spencer
Between-pregnancy biological variability of maternal serum alpha-fetoprotein and free beta hCG: implications for Down syndrome screening in subsequent pregnancies.
Prenatal diagnosis 1997;17(1):39-45.
1997: Kevin Spencer; F Muller; David A Aitken
Biochemical markers of trisomy 21 in amniotic fluid.
Prenatal diagnosis 1997;17(1):31-7.
1996: Kevin Spencer; Euan Wallace; S Ritoe
Second-trimester dimeric inhibin-A in Down's syndrome screening.
Prenatal diagnosis 1996;16(12):1101-10.
1996: C H Laundon; Kevin Spencer; James N Macri; R W Anderson; P D Buchanan
Free beta hCG screening of hydropic and non-hydropic Turner syndrome pregnancies.
Prenatal diagnosis 1996;16(9):853-6.
1996: Kevin Spencer; David A Aitken; James N Macri; P D Buchanan
Urine free beta hCG and beta core in pregnancies affected by Down's syndrome.
Prenatal diagnosis 1996;16(7):605-13.
1996: R Zimmermann; T M Reynolds; R John; Kevin Spencer; I Bartels; E Coombes; S Trevor
Age-independent indices in second-trimester serum screening for Down's syndrome are useless.
Prenatal diagnosis 1996;16(1):79-82.
1995: Kevin Spencer
The influence of gravidity on Down's syndrome screening with free beta hCG.
Prenatal diagnosis 1995;15(1):87-9.
1994: Kevin Spencer; David A Aitken; Jennifer A Crossley; G McCaw; E Berry; R Anderson; J Michael Connor; James N Macri
First trimester biochemical screening for trisomy 21: the role of free beta hCG, alpha fetoprotein and pregnancy associated plasma protein A.
Annals of clinical biochemistry 1994;31 ( Pt 5)():447-54.
1994: Kevin Spencer; R Salonen; F Muller
Down's syndrome screening in multiple pregnancies using alpha-fetoprotein and free beta hCG.
Prenatal diagnosis 1994;14(7):537-42.
1994: Kevin Spencer
Antenatal maternal serum profiles.
British journal of hospital medicine 1994;51(5):243-6.
1994: James N Macri; Kevin Spencer; K Garver; P D Buchanan; B Say; N J Carpenter; F Muller; A Boué
Maternal serum free beta hCG screening: results of studies including 480 cases of Down syndrome.
Prenatal diagnosis 1994;14(2):97-103.
1993: Kevin Spencer; A S Mallard; E J Coombes; James N Macri
Prenatal screening for trisomy 18 with free beta human chorionic gonadotrophin as a marker.
BMJ (Clinical research ed.) 1993;307(6917):1455-8.
1993: Kevin Spencer; P Carpenter
Prospective study of prenatal screening for Down's syndrome with free beta human chorionic gonadotrophin.
BMJ (Clinical research ed.) 1993;307(6907):764-9.
1993: David A Aitken; G McCaw; Jennifer A Crossley; E Berry; J Michael Connor; Kevin Spencer; James N Macri
First-trimester biochemical screening for fetal chromosome abnormalities and neural tube defects.
Prenatal diagnosis 1993;13(8):681-9.
1993: James N Macri; Kevin Spencer; D Aitken; K Garver; P D Buchanan; F Muller; A Boue
First-trimester free beta (hCG) screening for Down syndrome.
Prenatal diagnosis 1993;13(7):557-62.
1993: Kevin Spencer; James N Macri; R W Anderson; David A Aitken; E Berry; Jennifer A Crossley; P J Wood; E J Coombes; M Stroud; D J Worthington
Dual analyte immunoassay in neural tube defect and Down's syndrome screening: results of a multicentre clinical trial.
Annals of clinical biochemistry 1993;30 ( Pt 4)():394-401.
1993: Kevin Spencer; James N Macri; E J Coombes; A M Ward
Antenatal screening for Down's syndrome.
BMJ (Clinical research ed.) 1993;306(6892):1616.
1993: Kevin Spencer; James N Macri; P Carpenter; R Anderson; D A Krantz
Stability of intact chorionic gonadotropin (hCG) in serum, liquid whole blood, and dried whole-blood filter-paper spots: impact on screening for Down syndrome by measurement of free beta-hCG subunit.
Clinical chemistry 1993;39(6):1064-8.
1993: Kevin Spencer; P J Wood; F W Anthony
Elevated levels of maternal serum inhibin immunoreactivity in second trimester pregnancies affected by Down's syndrome.
Annals of clinical biochemistry 1993;30 ( Pt 2)():219-20.
1993: James N Macri; Kevin Spencer; R W Anderson; E J Cook
Free beta-chorionic gonadotropin: a cross-reactivity study of two immunometric assays used in prenatal maternal serum screening for Down's syndrome.
Annals of clinical biochemistry 1993;30 ( Pt 1)():94-8.
1993: Kevin Spencer
Free alpha-subunit of human chorionic gonadotropin in Down syndrome.
American journal of obstetrics and gynecology 1993;168(1 Pt 1):132-5.
1992: Kevin Spencer; E J Coombes; A S Mallard; A M Ward
Free beta human choriogonadotropin in Down's syndrome screening: a multicentre study of its role compared with other biochemical markers.
Annals of clinical biochemistry 1992;29 ( Pt 5)():506-18.
1992: Kevin Spencer; James N Macri; David A Aitken; J M Connor
Free beta-hCG as first-trimester marker for fetal trisomy.
Lancet 1992;339(8807):1480.
1992: Kevin Spencer; James N Macri
Early detection of Down's syndrome using free beta human choriogonadotropin.
Annals of clinical biochemistry 1992;29 ( Pt 3)():349-50.
1992: Kevin Spencer; P Carpenter
Risk of Down's syndrome and amniocentesis rate.
BMJ (Clinical research ed.) 1992;304(6827):640-1.
1991: Kevin Spencer
Evaluation of an assay of the free beta-subunit of choriogonadotropin and its potential value in screening for Down's syndrome.
Clinical chemistry 1991;37(6):809-14.
1991: Kevin Spencer
Maternal serum CA125 is not a second trimester marker for Down's syndrome.
Annals of clinical biochemistry 1991;28 ( Pt 3)():299-300.
1988: Kevin Spencer; P Carpenter
Maternal serum neurone specific enolase in the diagnosis of anencephaly and other neural tube defects.
Annals of clinical biochemistry 1988;25 ( Pt 6)():668-9.
1988: Kevin Spencer; P Carpenter
Neurone specific enolase in amniotic fluid: a potential marker of anencephaly.
Annals of clinical biochemistry 1988;25 ( Pt 1)():85-8.
1985: Kevin Spencer; P Carpenter
Screening for Down's syndrome using serum alpha fetoprotein: a retrospective study indicating caution.
British medical journal (Clinical research ed.) 1985;290(6486):1940-3.
1983: Kevin Spencer; E J Coombes; P J Wood
The measurement of amniotic fluid alpha 2 macroglobulin by fixed time kinetic immunoturbidimetry.
Journal of clinical chemistry and clinical biochemistry. Zeitschrift für klinische Chemie und klinische Biochemie 1983;21(3):133-7.
1982: E J Coombes; P J Wood; Kevin Spencer; G F Batstone
Improved discrimination in the detection of neural tube defects: five biochemical tests compared.
Clinica chimica acta; international journal of clinical chemistry 1982;122(2):249-59.
1982: P J Wood; E Coombes; Kevin Spencer
Concanavalin A binding of alpha-fetoprotein in the diagnosis of neural tube defects--a word of caution.
Clinical chemistry 1982;28(5):1231.