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Kevin Spencer
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54
Nicolaides, Kypros
25
Cowans, Nicholas
16
Liao, AW
13
Macri, James
12
Ong, C Y T
11
Aitken, David
8
Bindra, Renu
7
Crossley, Jennifer
6
Papageorghiou, Aris
6
Stamatopoulou, Anastasia
5
Yu, C K H
4
Avgidou, Kyriaki
4
Heath, Victoria
3
Geerts, Lut
3
Makrydimas, George
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All Publications
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2009: Spencer Kevin; Enofe Osasumwen; Cowans Nicholas J; Stamatopoulou Anastasia
Is maternal renal disease a cause of elevated free beta-hCG in first trimester aneuploidy screening?
Prenatal diagnosis 2009;29(11):1045-9.
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2009: Cowans Nicholas J; Stamatopoulou Anastasia; Maiz Nerea; Spencer Kevin; Nicolaides Kypros H
The impact of fetal gender on first trimester nuchal translucency and maternal serum free beta-hCG and PAPP-A MoM in normal and trisomy 21 pregnancies.
Prenatal diagnosis 2009;29(6):578-81.
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2009: Cowans Nicholas J; Stamatopoulou Anastasia; Spencer Kevin
The effect of Rhesus status on first-trimester pregnancy screening markers free beta human chorionic gonadotropin, pregnancy-associated plasma protein-A and nuchal translucency.
Prenatal diagnosis 2009;29(5):505-7.
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2008: Spencer Kevin; Cowans Nicholas J; Uldbjerg Niels; Vereecken Annie; Tørring Niels
First trimester intact hCG as an early marker of trisomy 21: a promise unrecognised?
Prenatal diagnosis 2008;28(12):1156-9.
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2008: Spencer K; Cowans N J; Nicolaides K H
Maternal serum inhibin-A and activin-A levels in the first trimester of pregnancies developing pre-eclampsia.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2008;32(5):622-6.
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2008: Kagan K O; Wright D; Spencer K; Molina F S; Nicolaides K H
First-trimester screening for trisomy 21 by free beta-human chorionic gonadotropin and pregnancy-associated plasma protein-A: impact of maternal and pregnancy characteristics.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2008;31(5):493-502.
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2008: Spencer Kevin; Cowans Nicholas J; Stamatopoulou Anastasia
Maternal serum ADAM12s in the late first trimester of pregnancies with Trisomy 21.
Prenatal diagnosis 2008;28(5):422-4.
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2008: Spencer Kevin; Cowans Nicholas J; Uldbjerg Niels; Tørring Niels
First-trimester ADAM12s as early markers of trisomy 21: a promise still unfulfilled?
Prenatal diagnosis 2008;28(4):338-42.
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2008: Spencer Kevin; Cowans Nicholas J; Stamatopoulou Anastasia
ADAM12s in maternal serum as a potential marker of pre-eclampsia.
Prenatal diagnosis 2008;28(3):212-6.
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2008: Makrydimas George; Sotiriadis Alexandros; Savvidou Makrina D; Spencer Kevin; Nicolaides Kypros H
Physiological distribution of placental growth factor and soluble Flt-1 in early pregnancy.
Prenatal diagnosis 2008;28(3):175-9.
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2008: Spencer Kevin; Vereecken Annie; Cowans Nicholas J
Maternal serum ADAM12s as a potential marker of trisomy 21 prior to 10 weeks of gestation.
Prenatal diagnosis 2008;28(3):209-11.
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2008: Cowans Nicholas J; Spencer Kevin; Meiri Hamutal
First-trimester maternal placental protein 13 levels in pregnancies resulting in adverse outcomes.
Prenatal diagnosis 2008;28(2):121-5.
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2008: Spencer K; Cowans N J; Molina F; Kagan K O; Nicolaides K H
First-trimester ultrasound and biochemical markers of aneuploidy and the prediction of preterm or early preterm delivery.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2008;31(2):147-52.
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2008: Spencer Kevin; Kagan Karl O; Nicolaides Kypros H
Screening for trisomy 21 in twin pregnancies in the first trimester: an update of the impact of chorionicity on maternal serum markers.
Prenatal diagnosis 2008;28(1):49-52.
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2008: Spencer Kevin; Cowans Nicholas J; Nicolaides Kypros H
Low levels of maternal serum PAPP-A in the first trimester and the risk of pre-eclampsia.
Prenatal diagnosis 2008;28(1):7-10.
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2008: Spencer K; Cowans N J; Avgidou K; Molina F; Nicolaides K H
First-trimester biochemical markers of aneuploidy and the prediction of small-for-gestational age fetuses.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2008;31(1):15-9.
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2007: Spencer Kevin; Cowans Nicholas J; Stamatopoulou Anastasia
Maternal serum ADAM12s as a marker of rare aneuploidies in the first or second trimester of pregnancy.
Prenatal diagnosis 2007;27(13):1233-7.
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2007: Spencer Kevin; Cowans Nicholas J
ADAM12 as a marker of trisomy 18 in the first and second trimester of pregnancy.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2007;20(9):645-50.
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2007: Kagan K O; Frisova V; Nicolaides K H; Spencer K
Dose dependency between cigarette consumption and reduced maternal serum PAPP-A levels at 11-13+6 weeks of gestation.
Prenatal diagnosis 2007;27(9):849-53.
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2007: Christiansen Michael; Spencer Kevin; Laigaard Jennie; Cowans Nicholas J; Larsen Severin Olesen; Wewer Ulla M
ADAM 12 as a second-trimester maternal serum marker in screening for Down syndrome.
Prenatal diagnosis 2007;27(7):611-5.
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2007: Cowans Nicholas J; Spencer Kevin
First-trimester ADAM12 and PAPP-A as markers for intrauterine fetal growth restriction through their roles in the insulin-like growth factor system.
Prenatal diagnosis 2007;27(3):264-71.
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2007: Spencer Kevin; Cowans Nicholas J; Chefetz Ilana; Tal Joseph; Kuhnreich Ido; Meiri Hamutal
Second-trimester uterine artery Doppler pulsatility index and maternal serum PP13 as markers of pre-eclampsia.
Prenatal diagnosis 2007;27(3):258-63.
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2007: Spencer Kevin
Aneuploidy screening in the first trimester.
American journal of medical genetics. Part C, Seminars in medical genetics 2007;145C(1):18-32.
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2007: Spencer K; Cowans N J; Chefetz I; Tal J; Meiri H
First-trimester maternal serum PP-13, PAPP-A and second-trimester uterine artery Doppler pulsatility index as markers of pre-eclampsia.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2007;29(2):128-34.
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2007: Cowans Nicholas J; Spencer Kevin
Is there an association between maternal ABO and rhesus blood groups and the first-trimester serum markers free beta-hCG and PAPP-A used for the detection of fetal aneuploidy?
Prenatal diagnosis 2007;27(1):64-7.
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2006: Makrydimas George; Sotiriadis Alexandros; Spencer Kevin; Cowans Nicholas J; Nicolaides Kypros H
ADAM12-s in coelomic fluid and maternal serum in early pregnancy.
Prenatal diagnosis 2006;26(13):1197-200.
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2006: Spencer K; Cowans N J; Avgidou K; Nicolaides K H
First-trimester ultrasound and biochemical markers of aneuploidy and the prediction of impending fetal death.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2006;28(5):637-43.
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2006: Laigaard Jennie; Spencer Kevin; Christiansen Michael; Cowans Nicholas J; Larsen Severin Olesen; Pedersen Bent Norgaard; Wewer Ulla M
ADAM 12 as a first-trimester maternal serum marker in screening for Down syndrome.
Prenatal diagnosis 2006;26(10):973-9.
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2006: Spencer K; Yu C K H; Savvidou M; Papageorghiou A T; Nicolaides K H
Prediction of pre-eclampsia by uterine artery Doppler ultrasonography and maternal serum pregnancy-associated plasma protein-A, free beta-human chorionic gonadotropin, activin A and inhibin A at 22 + 0 to 24 + 6 weeks' gestation.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2006;27(6):658-63.
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2006: Papageorghiou Aris T; Avgidou Kyriaki; Spencer Kevin; Nix Barry; Nicolaides Kypros H
Sonographic screening for trisomy 13 at 11 to 13(+6) weeks of gestation.
American journal of obstetrics and gynecology 2006;194(2):397-401.
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2006: Falcon O; Auer M; Gerovassili A; Spencer K; Nicolaides K H
Screening for trisomy 21 by fetal tricuspid regurgitation, nuchal translucency and maternal serum free beta-hCG and PAPP-A at 11 + 0 to 13 + 6 weeks.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2006;27(2):151-5.
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2005: Cicero Simona; Spencer Kevin; Avgidou Kyriaki; Faiola Stefano; Nicolaides Kypros H
Maternal serum biochemistry at 11-13(+6) weeks in relation to the presence or absence of the fetal nasal bone on ultrasonography in chromosomally abnormal fetuses: an updated analysis of integrated ultrasound and biochemical screening.
Prenatal diagnosis 2005;25(11):977-83.
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2005: Spencer Kevin; Cicero Simona; Atzei Alessia; Otigbah Chineze; Nicolaides Kypros H
The influence of maternal insulin-dependent diabetes on fetal nuchal translucency thickness and first-trimester maternal serum biochemical markers of aneuploidy.
Prenatal diagnosis 2005;25(10):927-9.
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2005: Spencer Kevin; Yu Christina K H; Cowans Nicholas J; Otigbah Chineze; Nicolaides Kypros H
Prediction of pregnancy complications by first-trimester maternal serum PAPP-A and free beta-hCG and with second-trimester uterine artery Doppler.
Prenatal diagnosis 2005;25(10):949-53.
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2005: Makrydimas G; Vandecruys H; Sotiriadis A; Lakasing L; Spencer K; Nicolaides K H
Coelomic fluid leptin concentration in normal first-trimester pregnancies and missed miscarriages.
Fetal diagnosis and therapy 2005;20(5):406-9.
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2005: Cowans N J; Spencer K
First and second-trimester biochemical markers of chromosomal anomalies and their relationship to maternal haemoglobin levels.
Prenatal diagnosis 2005;25(8):693-9.
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2005: Avgidou Kyriaki; Papageorghiou Aris; Bindra Renu; Spencer Kevin; Nicolaides Kypros H
Prospective first-trimester screening for trisomy 21 in 30,564 pregnancies.
American journal of obstetrics and gynecology 2005;192(6):1761-7.
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2005: Spencer K; Heath V; El-Sheikhah A; Ong C Y T; Nicolaides K H
Ethnicity and the need for correction of biochemical and ultrasound markers of chromosomal anomalies in the first trimester: a study of Oriental, Asian and Afro-Caribbean populations.
Prenatal diagnosis 2005;25(5):365-9.
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2005: Spencer K; Crossley J A; Aitken D A; Nicolaides K H
Second-trimester levels of pregnancy-associated plasma protein-A and free beta-hCG in pregnancies with trisomy 13.
Prenatal diagnosis 2005;25(5):358-61.
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2005: Nicolaides K H; Spencer K; Avgidou K; Faiola S; Falcon O
Multicenter study of first-trimester screening for trisomy 21 in 75 821 pregnancies: results and estimation of the potential impact of individual risk-orientated two-stage first-trimester screening.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2005;25(3):221-6.
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2005: Spencer Kevin
First trimester maternal serum screening for Down's syndrome: an evaluation of the DPC Immulite 2000 free beta-hCG and pregnancy-associated plasma protein-A assays.
Annals of clinical biochemistry 2005;42(Pt 1):30-40.
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2005: Spencer Kevin; Yu Christina K H; Rembouskos George; Bindra Renu; Nicolaides Kypros H
First trimester sex hormone-binding globulin and subsequent development of preeclampsia or other adverse pregnancy outcomes.
Hypertension in pregnancy : official journal of the International Society for the Study of Hypertension in Pregnancy 2005;24(3):303-11.
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2005: Banerjee Subhasis; Smallwood Alan; Chambers Anne E; Papageorghiou Aris; Loosfelt Hugues; Spencer Kevin; Campbell Stuart; Nicolaides Kypros
A link between high serum levels of human chorionic gonadotrophin and chorionic expression of its mature functional receptor (LHCGR) in Down's syndrome pregnancies.
Reproductive biology and endocrinology : RB&E 2005;3():25.
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2004: Spencer K; Aitken D
Factors affecting women's preference for type of prenatal screening test for chromosomal anomalies.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2004;24(7):735-9.
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2004: Nicolaides K H; Heath V; Spencer K; Nix A B J
Nuchal translucency and gestational age.
Prenatal diagnosis 2004;24(10):833-4; author reply 834-5.
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2004: Yu C K H; Papageorghiou A T; Bindra R; Spencer K; Nicolaides K H
Second-trimester sex hormone-binding globulin and subsequent development of pre-eclampsia.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2004;16(3):158-62.
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2004: Yu C K H; Lakasing L; Papageorghiou A T; Spencer K; Nicolaides K H
Uterine artery Doppler and mid-trimester maternal plasma homocysteine in subsequent pre-eclampsia.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2004;16(2):134-9.
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2004: Ong C Y T; Liao A W; Munim S; Spencer K; Nicolaides K H
First-trimester maternal serum activin A in pre-eclampsia and fetal growth restriction.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2004;15(3):176-80.
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2004: Spencer Kevin; Bindra Renu; Cacho Anna Maria; Nicolaides Kypros H
The impact of correcting for smoking status when screening for chromosomal anomalies using maternal serum biochemistry and fetal nuchal translucency thickness in the first trimester of pregnancy.
Prenatal diagnosis 2004;24(3):169-73.
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2003: Spencer Kevin; Bindra Renu; Nicolaides Kypros H
Maternal weight correction of maternal serum PAPP-A and free beta-hCG MoM when screening for trisomy 21 in the first trimester of pregnancy.
Prenatal diagnosis 2003;23(10):851-5.
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2003: Spencer K; Bindra R; Nix A B J; Heath V; Nicolaides K H
Delta-NT or NT MoM: which is the most appropriate method for calculating accurate patient-specific risks for trisomy 21 in the first trimester?
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2003;22(2):142-8.
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2003: Spencer Kevin; de Kok J B; Swinkels D W
Increased total cell-free DNA in the serum of pregnant women carrying a fetus affected by trisomy 21.
Prenatal diagnosis 2003;23(7):580-3.
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2003: Spencer K; Crossley J A; Aitken D A; Nix A B J; Dunstan F D J; Williams K
The effect of temporal variation in biochemical markers of trisomy 21 across the first and second trimesters of pregnancy on the estimation of individual patient-specific risks and detection rates for Down's syndrome.
Annals of clinical biochemistry 2003;40(Pt 3):219-31.
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2003: Cicero Simona; Bindra Renu; Rembouskos Georgios; Spencer Kevin; Nicolaides Kypros H
Integrated ultrasound and biochemical screening for trisomy 21 using fetal nuchal translucency, absent fetal nasal bone, free beta-hCG and PAPP-A at 11 to 14 weeks.
Prenatal diagnosis 2003;23(4):306-10.
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2003: Spencer Kevin
The influence of different sample collection types on the levels of markers used for Down's syndrome screening as measured by the Kryptor Immunosassay system.
Annals of clinical biochemistry 2003;40(Pt 2):166-8.
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2003: Spencer Kevin; Spencer Christine E; Power Maureen; Dawson Carolynne; Nicolaides Kypros H
Screening for chromosomal abnormalities in the first trimester using ultrasound and maternal serum biochemistry in a one-stop clinic: a review of three years prospective experience.
BJOG : an international journal of obstetrics and gynaecology 2003;110(3):281-6.
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2003: Spencer Kevin; Nicolaides Kypros H
Screening for trisomy 21 in twins using first trimester ultrasound and maternal serum biochemistry in a one-stop clinic: a review of three years experience.
BJOG : an international journal of obstetrics and gynaecology 2003;110(3):276-80.
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2003: Talbot J A; Spencer K; Abushoufa R A
Detection of maternal serum hCG glycoform variants in the second trimester of pregnancies affected by Down syndrome using a lectin immunoassay.
Prenatal diagnosis 2003;23(1):1-5.
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2002: Spencer Kevin
Uptake of prenatal screening for chromosomal anomalies: impact of test results in a previous pregnancy.
Prenatal diagnosis 2002;22(13):1229-32.
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2002: Spencer K; Crossley J A; Aitken D A; Nix A B J; Dunstan F D J; Williams K
Temporal changes in maternal serum biochemical markers of trisomy 21 across the first and second trimester of pregnancy.
Annals of clinical biochemistry 2002;39(Pt 6):567-76.
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2002: Spencer Kevin; Cuckle Howard S
Screening for chromosomal anomalies in the first trimester: does repeat maternal serum screening improve detection rates?
Prenatal diagnosis 2002;22(10):903-6.
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2002: Spencer Kevin; Nicolaides Kypros H
A first trimester trisomy 13/trisomy 18 risk algorithm combining fetal nuchal translucency thickness, maternal serum free beta-hCG and PAPP-A.
Prenatal diagnosis 2002;22(10):877-9.
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2002: Spencer Kevin
Between pregnancy biological variability of first trimester markers of Down syndrome and the implications for screening in subsequent pregnancies: an issue revisited.
Prenatal diagnosis 2002;22(10):874-6.
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2002: Bindra R; Heath V; Liao A; Spencer K; Nicolaides K H
One-stop clinic for assessment of risk for trisomy 21 at 11-14 weeks: a prospective study of 15 030 pregnancies.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2002;20(3):219-25.
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2002: Spencer K; Talbot J A; Abushoufa R A
Maternal serum hyperglycosylated human chorionic gonadotrophin (HhCG) in the first trimester of pregnancies affected by Down syndrome, using a sialic acid-specific lectin immunoassay.
Prenatal diagnosis 2002;22(8):656-62.
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2001: Spencer K
Age related detection and false positive rates when screening for Down's syndrome in the first trimester using fetal nuchal translucency and maternal serum free betahCG and PAPP-A.
BJOG : an international journal of obstetrics and gynaecology 2001;108(10):1043-6.
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2001: Ong C Y; Liao A W; Cacho A M; Spencer K; Nicolaides K H
First-trimester maternal serum levels of placenta growth factor as predictor of preeclampsia and fetal growth restriction.
Obstetrics and gynecology 2001;98(4):608-11.
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2001: Spencer K; Liao A W; Ong C Y; Geerts L; Nicolaides K H
First trimester maternal serum placenta growth factor (PIGF)concentrations in pregnancies with fetal trisomy 21 or trisomy 18.
Prenatal diagnosis 2001;21(9):718-22.
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2001: Spencer K
Screening for trisomy 21 in twin pregnancies in the first trimester: does chorionicity impact on maternal serum free beta-hCG or PAPP-A levels?
Prenatal diagnosis 2001;21(9):715-7.
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2001: Spencer K; Liao A W; Ong C Y; Flack N J; Nicolaides K H
Maternal serum activin A and inhibin A in trisomy 18 pregnancies at 10-14 weeks.
Prenatal diagnosis 2001;21(7):571-4.
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2001: Liao A W; Heath V; Kametas N; Spencer K; Nicolaides K H
First-trimester screening for trisomy 21 in singleton pregnancies achieved by assisted reproduction.
Human reproduction (Oxford, England) 2001;16(7):1501-4.
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2001: Spencer K
Between pregnancy biological variability of first trimester markers of Down syndrome: implications for screening in subsequent pregnancies.
Prenatal diagnosis 2001;21(6):445-7.
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2001: Spencer K; Liao A W; Ong C Y; Geerts L; Nicolaides K H
Maternal serum levels of dimeric inhibin A in pregnancies affected by trisomy 21 in the first trimester.
Prenatal diagnosis 2001;21(6):441-4.
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2001: Spencer K; Liao A W; Skentou H; Ong C Y; Nicolaides K H
Maternal serum levels of total activin-A in first-trimester trisomy 21 pregnancies.
Prenatal diagnosis 2001;21(4):270-3.
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2000: Liao A W; Snijders R; Geerts L; Spencer K; Nicolaides K H
Fetal heart rate in chromosomally abnormal fetuses.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 2000;16(7):610-3.
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2000: Spencer K; Ong C Y; Liao A W; Papademetriou D; Nicolaides K H
First trimester markers of trisomy 21 and the influence of maternal cigarette smoking status.
Prenatal diagnosis 2000;20(10):852-3.
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2000: Spencer K; Ong C Y; Liao A W; Nicolaides K H
The influence of parity and gravidity on first trimester markers of chromosomal abnormality.
Prenatal diagnosis 2000;20(10):792-4.
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2000: Spencer K; Spencer C E; Power M; Moakes A; Nicolaides K H
One stop clinic for assessment of risk for fetal anomalies: a report of the first year of prospective screening for chromosomal anomalies in the first trimester.
BJOG : an international journal of obstetrics and gynaecology 2000;107(10):1271-5.
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2000: Ong C Y; Liao A W; Spencer K; Munim S; Nicolaides K H
First trimester maternal serum free beta human chorionic gonadotrophin and pregnancy associated plasma protein A as predictors of pregnancy complications.
BJOG : an international journal of obstetrics and gynaecology 2000;107(10):1265-70.
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2000: Spencer K; Ong C Y; Liao A W; Papademetriou D; Nicolaides K H
The influence of fetal sex in screening for trisomy 21 by fetal nuchal translucency, maternal serum free beta-hCG and PAPP-A at 10-14 weeks of gestation.
Prenatal diagnosis 2000;20(8):673-5.
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2000: Spencer K
Second-trimester prenatal screening for Down syndrome and the relationship of maternal serum biochemical markers to pregnancy complications with adverse outcome.
Prenatal diagnosis 2000;20(8):652-6.
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2000: Spencer K
The influence of fetal sex in screening for Down syndrome in the second trimester using AFP and free beta-hCG.
Prenatal diagnosis 2000;20(8):648-51.
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2000: Spencer K; Heath V; Flack N; Ong C; Nicolaides K H
First trimester maternal serum AFP and total hCG in aneuploidies other than trisomy 21.
Prenatal diagnosis 2000;20(8):635-9.
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2000: Spencer K; Liao A W; Skentou H; Cicero S; Nicolaides K H
Screening for triploidy by fetal nuchal translucency and maternal serum free beta-hCG and PAPP-A at 10-14 weeks of gestation.
Prenatal diagnosis 2000;20(6):495-9.
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2000: Spencer K; Ong C Y; Liao A W; Nicolaides K H
The influence of ethnic origin on first trimester biochemical markers of chromosomal abnormalities.
Prenatal diagnosis 2000;20(6):491-4.
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2000: Spencer K; Ong C; Skentou H; Liao A W; H Nicolaides K
Screening for trisomy 13 by fetal nuchal translucency and maternal serum free beta-hCG and PAPP-A at 10-14 weeks of gestation.
Prenatal diagnosis 2000;20(5):411-6.
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2000: Spencer K; Tul N; Nicolaides K H
Maternal serum free beta-hCG and PAPP-A in fetal sex chromosome defects in the first trimester.
Prenatal diagnosis 2000;20(5):390-4.
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2000: Spencer K; Berry E; Crossley J A; Aitken D A; Nicolaides K H
Is maternal serum total hCG a marker of trisomy 21 in the first trimester of pregnancy?
Prenatal diagnosis 2000;20(4):311-7.
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2000: Spencer K
Screening for trisomy 21 in twin pregnancies in the first trimester using free beta-hCG and PAPP-A, combined with fetal nuchal translucency thickness.
Prenatal diagnosis 2000;20(2):91-5.
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1999: Spencer K
Second trimester prenatal screening for Down's syndrome using alpha-fetoprotein and free beta hCG: a seven year review.
British journal of obstetrics and gynaecology 1999;106(12):1287-93.
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1999: Spencer K
The influence of smoking on maternal serum PAPP-A and free beta hCG levels in the first trimester of pregnancy.
Prenatal diagnosis 1999;19(11):1065-6.
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1999: Spencer K; Souter V; Tul N; Snijders R; Nicolaides K H
A screening program for trisomy 21 at 10-14 weeks using fetal nuchal translucency, maternal serum free beta-human chorionic gonadotropin and pregnancy-associated plasma protein-A.
Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology 1999;13(4):231-7.
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1999: Spencer K
Accuracy of Down's syndrome risks produced in a prenatal screening program.
Annals of clinical biochemistry 1999;36 ( Pt 1)():101-3.
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1998: Spencer K; Carpenter P
Is prostate-specific antigen a marker for pregnancies affected by Down syndrome?
Clinical chemistry 1998;44(11):2362-5.
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1998: Spencer K
The influence of smoking on maternal serum AFP and free beta hCG levels and the impact on screening for Down syndrome.
Prenatal diagnosis 1998;18(3):225-34.
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1997: Spencer K; Muller F; Aitken D A
Amniotic fluid and maternal serum levels of CA125 in pregnancies affected by Down syndrome: a re-evaluation of the role of CA125 in Down syndrome screening.
Prenatal diagnosis 1997;17(8):701-6.
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1997: Sebire N J; Spencer K; Noble P L; Hughes K; Nicolaides K H
Maternal serum alpha-fetoprotein in fetal neural tube and abdominal wall defects at 10 to 14 weeks of gestation.
British journal of obstetrics and gynaecology 1997;104(7):849-51.
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1997: Spencer K; Noble P; Snijders R J; Nicolaides K H
First-trimester urine free beta hCG, beta core, and total oestriol in pregnancies affected by Down's syndrome: implications for first-trimester screening with nuchal translucency and serum free beta hCG.
Prenatal diagnosis 1997;17(6):525-38.
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1997: Spencer K
Between-pregnancy biological variability of maternal serum alpha-fetoprotein and free beta hCG: implications for Down syndrome screening in subsequent pregnancies.
Prenatal diagnosis 1997;17(1):39-45.
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1997: Spencer K; Muller F; Aitken D A
Biochemical markers of trisomy 21 in amniotic fluid.
Prenatal diagnosis 1997;17(1):31-7.
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1996: Spencer K; Wallace E M; Ritoe S
Second-trimester dimeric inhibin-A in Down's syndrome screening.
Prenatal diagnosis 1996;16(12):1101-10.
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1996: Laundon C H; Spencer K; Macri J N; Anderson R W; Buchanan P D
Free beta hCG screening of hydropic and non-hydropic Turner syndrome pregnancies.
Prenatal diagnosis 1996;16(9):853-6.
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1996: Spencer K; Aitken D A; Macri J N; Buchanan P D
Urine free beta hCG and beta core in pregnancies affected by Down's syndrome.
Prenatal diagnosis 1996;16(7):605-13.
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1996: Zimmermann R; Reynolds T M; John R; Spencer K; Bartels I; Coombes E; Trevor S
Age-independent indices in second-trimester serum screening for Down's syndrome are useless.
Prenatal diagnosis 1996;16(1):79-82.
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1995: Spencer K
The influence of gravidity on Down's syndrome screening with free beta hCG.
Prenatal diagnosis 1995;15(1):87-9.
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1994: Spencer K; Aitken D A; Crossley J A; McCaw G; Berry E; Anderson R; Connor J M; Macri J N
First trimester biochemical screening for trisomy 21: the role of free beta hCG, alpha fetoprotein and pregnancy associated plasma protein A.
Annals of clinical biochemistry 1994;31 ( Pt 5)():447-54.
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1994: Spencer K; Salonen R; Muller F
Down's syndrome screening in multiple pregnancies using alpha-fetoprotein and free beta hCG.
Prenatal diagnosis 1994;14(7):537-42.
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1994: Spencer K
Antenatal maternal serum profiles.
British journal of hospital medicine 1994;51(5):243-6.
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1994: Macri J N; Spencer K; Garver K; Buchanan P D; Say B; Carpenter N J; Muller F; Boué A
Maternal serum free beta hCG screening: results of studies including 480 cases of Down syndrome.
Prenatal diagnosis 1994;14(2):97-103.
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1993: Spencer K; Mallard A S; Coombes E J; Macri J N
Prenatal screening for trisomy 18 with free beta human chorionic gonadotrophin as a marker.
BMJ (Clinical research ed.) 1993;307(6917):1455-8.
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1993: Spencer K; Carpenter P
Prospective study of prenatal screening for Down's syndrome with free beta human chorionic gonadotrophin.
BMJ (Clinical research ed.) 1993;307(6907):764-9.
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1993: Aitken D A; McCaw G; Crossley J A; Berry E; Connor J M; Spencer K; Macri J N
First-trimester biochemical screening for fetal chromosome abnormalities and neural tube defects.
Prenatal diagnosis 1993;13(8):681-9.
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1993: Macri J N; Spencer K; Aitken D; Garver K; Buchanan P D; Muller F; Boue A
First-trimester free beta (hCG) screening for Down syndrome.
Prenatal diagnosis 1993;13(7):557-62.
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1993: Spencer K; Macri J N; Anderson R W; Aitken D A; Berry E; Crossley J A; Wood P J; Coombes E J; Stroud M; Worthington D J
Dual analyte immunoassay in neural tube defect and Down's syndrome screening: results of a multicentre clinical trial.
Annals of clinical biochemistry 1993;30 ( Pt 4)():394-401.
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1993: Spencer K; Macri J N; Coombes E J; Ward A M
Antenatal screening for Down's syndrome.
BMJ (Clinical research ed.) 1993;306(6892):1616.
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1993: Spencer K; Macri J N; Carpenter P; Anderson R; Krantz D A
Stability of intact chorionic gonadotropin (hCG) in serum, liquid whole blood, and dried whole-blood filter-paper spots: impact on screening for Down syndrome by measurement of free beta-hCG subunit.
Clinical chemistry 1993;39(6):1064-8.
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1993: Spencer K; Wood P J; Anthony F W
Elevated levels of maternal serum inhibin immunoreactivity in second trimester pregnancies affected by Down's syndrome.
Annals of clinical biochemistry 1993;30 ( Pt 2)():219-20.
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1993: Macri J N; Spencer K; Anderson R W; Cook E J
Free beta-chorionic gonadotropin: a cross-reactivity study of two immunometric assays used in prenatal maternal serum screening for Down's syndrome.
Annals of clinical biochemistry 1993;30 ( Pt 1)():94-8.
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1993: Spencer K
Free alpha-subunit of human chorionic gonadotropin in Down syndrome.
American journal of obstetrics and gynecology 1993;168(1 Pt 1):132-5.
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1992: Spencer K; Coombes E J; Mallard A S; Ward A M
Free beta human choriogonadotropin in Down's syndrome screening: a multicentre study of its role compared with other biochemical markers.
Annals of clinical biochemistry 1992;29 ( Pt 5)():506-18.
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1992: Spencer K; Macri J N; Aitken D A; Connor J M
Free beta-hCG as first-trimester marker for fetal trisomy.
Lancet 1992;339(8807):1480.
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1992: Spencer K; Macri J N
Early detection of Down's syndrome using free beta human choriogonadotropin.
Annals of clinical biochemistry 1992;29 ( Pt 3)():349-50.
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1992: Spencer K; Carpenter P
Risk of Down's syndrome and amniocentesis rate.
BMJ (Clinical research ed.) 1992;304(6827):640-1.
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1991: Spencer K
Evaluation of an assay of the free beta-subunit of choriogonadotropin and its potential value in screening for Down's syndrome.
Clinical chemistry 1991;37(6):809-14.
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1991: Spencer K
Maternal serum CA125 is not a second trimester marker for Down's syndrome.
Annals of clinical biochemistry 1991;28 ( Pt 3)():299-300.
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1988: Spencer K; Carpenter P
Maternal serum neurone specific enolase in the diagnosis of anencephaly and other neural tube defects.
Annals of clinical biochemistry 1988;25 ( Pt 6)():668-9.
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1988: Spencer K; Carpenter P
Neurone specific enolase in amniotic fluid: a potential marker of anencephaly.
Annals of clinical biochemistry 1988;25 ( Pt 1)():85-8.
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1985: Spencer K; Carpenter P
Screening for Down's syndrome using serum alpha fetoprotein: a retrospective study indicating caution.
British medical journal (Clinical research ed.) 1985;290(6486):1940-3.
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1983: Spencer K; Coombes E J; Wood P J
The measurement of amniotic fluid alpha 2 macroglobulin by fixed time kinetic immunoturbidimetry.
Journal of clinical chemistry and clinical biochemistry. Zeitschrift für klinische Chemie und klinische Biochemie 1983;21(3):133-7.
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1982: Coombes E J; Wood P J; Spencer K; Batstone G F
Improved discrimination in the detection of neural tube defects: five biochemical tests compared.
Clinica chimica acta; international journal of clinical chemistry 1982;122(2):249-59.
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1982: Wood P J; Coombes E; Spencer K
Concanavalin A binding of alpha-fetoprotein in the diagnosis of neural tube defects--a word of caution.
Clinical chemistry 1982;28(5):1231.
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