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David Spiegelhalter

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Sylwia Bujkiewicz; Nicola J Cooper; Keith R Abrams; Alex J Sutton; David J Spiegelhalter
Transparent interactive decision interrogator-reply to letter to the editor by Michael Coory.
Tim Rakow; Catherine Bull; Rebecca J Wright; David J Spiegelhalter
Simple and multistate survival curves: can people learn to use them?
Rebecca Turner; Stanislaw J Urbaniak; Robert Webster; Dilly O C Anumba; Myfanwy Lloyd-Jones; Gordon C S Smith; David J Spiegelhalter; Hazel Squires; John W Stevens; Michael J Sweeting; Simon G Thompson
Routine antenatal anti-D prophylaxis in women who are Rh(D) negative: meta-analyses adjusted for differences in study design and quality.

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2013: Sylwia Bujkiewicz; Nicola J Cooper; Keith R Abrams; Alex J Sutton; David J Spiegelhalter
Transparent interactive decision interrogator-reply to letter to the editor by Michael Coory.
Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 2013;16(1):216-7.
2012: Tim Rakow; Catherine Bull; Rebecca J Wright; David J Spiegelhalter
Simple and multistate survival curves: can people learn to use them?
Medical decision making : an international journal of the Society for Medical Decision Making 2012;32(6):792-804.
2012: Rebecca Turner; Stanislaw J Urbaniak; Robert Webster; Dilly O C Anumba; Myfanwy Lloyd-Jones; Gordon C S Smith; David J Spiegelhalter; Hazel Squires; John W Stevens; Michael J Sweeting; Simon G Thompson
Routine antenatal anti-D prophylaxis in women who are Rh(D) negative: meta-analyses adjusted for differences in study design and quality.
PloS one 2012;7(2):e30711.
2011: David J Spiegelhalter; Hauke Riesch
Don't know, can't know: embracing deeper uncertainties when analysing risks.
Philosophical transactions. Series A, Mathematical, physical, and engineering sciences 2011;369(1956):4730-50.
2011: Sylwia Bujkiewicz; Nicola J Cooper; Neil Hawkins; Hayley E Jones; Monica C W Lai; David J Spiegelhalter; Hazel Squires; Keith R Abrams; Alex J Sutton
Development of a transparent interactive decision interrogator to facilitate the decision-making process in health care.
Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 2011;14(5):768-76.
2010: Beat Neuenschwander; Gorana Capkun-Niggli; Michael Branson; David J Spiegelhalter
Summarizing historical information on controls in clinical trials.
Clinical trials (London, England) 2010;7(1):5-18.
2009: Beat Neuenschwander; Michael Branson; David J Spiegelhalter
A note on the power prior.
Statistics in medicine 2009;28(28):3562-6.
2009: David Lunn; David J Spiegelhalter; Andrew Thomas; Nicky Best
Rejoinder to commentaries on 'The BUGS project: Evolution, critique and future directions'.
Statistics in medicine 2009;28(25):3081-2.
2009: David Lunn; David J Spiegelhalter; Andrew Thomas; Nicky Best
The BUGS project: Evolution, critique and future directions.
Statistics in medicine 2009;28(25):3049-67.
2009: M Bardsley; David J Spiegelhalter; I Blunt; X Chitnis; A Roberts; S Bharania
Using routine intelligence to target inspection of healthcare providers in England.
Quality & safety in health care 2009;18(3):189-94.
2009: Hayley E Jones; David J Spiegelhalter
Accounting for regression-to-the-mean in tests for recent changes in institutional performance: analysis and power.
Statistics in medicine 2009;28(12):1645-67.
2009: David Lunn; Nicky Best; David J Spiegelhalter; Gordon Graham; Beat Neuenschwander
Combining MCMC with 'sequential' PKPD modelling.
Journal of pharmacokinetics and pharmacodynamics 2009;36(1):19-38.
2008: John Suckling; David Ohlssen; Christopher Andrew; Glyn Johnson; steven williams; Martin Graves; Chi-Hua Chen; David J Spiegelhalter; Ed Bullmore
Components of variance in a multicentre functional MRI study and implications for calculation of statistical power.
Human brain mapping 2008;29(10):1111-22.
2008: J Schulman; David J Spiegelhalter; G Parry
How to interpret your dot: decoding the message of clinical performance indicators.
Journal of perinatology : official journal of the California Perinatal Association 2008;28(9):588-96.
2008: David J Spiegelhalter
Understanding uncertainty.
Annals of family medicine 2008;6(3):196-7.
2008: Hayley E Jones; David I Ohlssen; David J Spiegelhalter
Use of the false discovery rate when comparing multiple health care providers.
Journal of clinical epidemiology 2008;61(3):232-240.
2008: Ann Louise Kinmonth; Nicholas J Wareham; Wendy Hardeman; Stephen Sutton; A Toby Prevost; Thomas Fanshawe; Kate M Williams; Ulf Ekelund; David J Spiegelhalter; Simon J Griffin
Efficacy of a theory-based behavioural intervention to increase physical activity in an at-risk group in primary care (ProActive UK): a randomised trial.
Lancet 2008;371(9606):41-8.
2008: A Sarah Walker; David J Spiegelhalter; Derrick W Crook; David Wyllie; James Morris; Tim E A Peto
Fairness of financial penalties to improve control of Clostridium difficile.
BMJ (Clinical research ed.) 2008;337():a2097.
2007: A Toby Prevost; Dan Mason; Simon Griffin; Ann Louise Kinmonth; Stephen Sutton; David J Spiegelhalter
Allowing for correlations between correlations in random-effects meta-analysis of correlation matrices.
Psychological methods 2007;12(4):434-50.
2007: Troels Ring; David J Spiegelhalter
Risk of intracranial aneurysm bleeding in autosomal-dominant polycystic kidney disease.
Kidney international 2007;72(11):1400-2.
2007: D I Ohlssen; Linda D Sharples; David J Spiegelhalter
Flexible random-effects models using Bayesian semi-parametric models: applications to institutional comparisons.
Statistics in medicine 2007;26(9):2088-112.
2007: Owen J Arthurs; T Donovan; David J Spiegelhalter; John D Pickard; Simon Boniface
Intracortically distributed neurovascular coupling relationships within and between human somatosensory cortices.
Cerebral cortex (New York, N.Y. : 1991) 2007;17(3):661-8.
2007: A Gorst-Rasmussen; David J Spiegelhalter; C Bull
Monitoring the introduction of a surgical intervention with long-term consequences.
Statistics in medicine 2007;26(3):512-31.
2007: Christopher J Weir; David J Spiegelhalter; Andrew P Grieve
Flexible design and efficient implementation of adaptive dose-finding studies.
Journal of biopharmaceutical statistics 2007;17(6):1033-50.
2006: John Douglas Pickard; David J Spiegelhalter; Marek Czosnyka
Health economics and the search for shunt-responsive symptomatic hydrocephalus in the elderly.
Journal of neurosurgery 2006;105(6):811-3; discussion 813-4.
2006: C Glümer; M Yuyun; S Griffin; D Farewell; David J Spiegelhalter; Ann Louise Kinmonth; Nicholas J Wareham
What determines the cost-effectiveness of diabetes screening?
Diabetologia 2006;49(7):1536-44.
2005: David J Spiegelhalter
Problems in assessing rates of infection with methicillin resistant Staphylococcus aureus.
BMJ (Clinical research ed.) 2005;331(7523):1013-5.
2005: David J Spiegelhalter
Handling over-dispersion of performance indicators.
Quality & safety in health care 2005;14(5):347-51.
2005: David J Spiegelhalter
Funnel plots for comparing institutional performance.
Statistics in medicine 2005;24(8):1185-202.
2005: Adrian Grant; Douglas Altman; Abdel B Babiker; Marion Campbell; F J Clemens; J H Darbyshire; Diana Elbourne; S K McLeer; M K B Parmar; Stuart J Pocock; David J Spiegelhalter; Matthew R Sydes; Anne E Walker; Sheila A Wallace
Issues in data monitoring and interim analysis of trials.
Health technology assessment (Winchester, England) 2005;9(7):1-238, iii-iv.
2005: Rebecca Turner; Simon G Thompson; David J Spiegelhalter
Prior distributions for the intracluster correlation coefficient, based on multiple previous estimates, and their application in cluster randomized trials.
Clinical trials (London, England) 2005;2(2):108-18.
2005: Tony O'Hagan; Christopher Joseph McCabe; Ron Akehurst; Alan Brennan; Andrew Briggs; Karl Claxton; Elisabeth Fenwick; Dennis Fryback; Mark J Sculpher; David J Spiegelhalter; Andrew R Willan
Incorporation of uncertainty in health economic modelling studies.
PharmacoEconomics 2005;23(6):529-36.
2004: David J Spiegelhalter
Monitoring clinical performance: a commentary.
The Journal of thoracic and cardiovascular surgery 2004;128(6):820-2.
2004: Kate Williams; A Toby Prevost; Simon Griffin; Wendy Hardeman; William Hollingworth; David J Spiegelhalter; Stephen Sutton; Ulf Ekelund; Nicholas J Wareham; Ann Louise Kinmonth
The ProActive trial protocol - a randomised controlled trial of the efficacy of a family-based, domiciliary intervention programme to increase physical activity among individuals at high risk of diabetes [ISRCTN61323766].
BMC public health 2004;4():48.
2004: Bruce Keogh; David J Spiegelhalter; Alan Bailey; James Roxburgh; Patrick Magee; Colin Hilton
The legacy of Bristol: public disclosure of individual surgeons' results.
BMJ (Clinical research ed.) 2004;329(7463):450-4.
2004: James thornton; J Hornbuckle; A Vail; David J Spiegelhalter; Malcolm Levene
Infant wellbeing at 2 years of age in the Growth Restriction Intervention Trial (GRIT): multicentred randomised controlled trial.
Lancet 2004;364(9433):513-20.
2004: Richard Lilford; Mohammed A Mohammed; David J Spiegelhalter; Richard Thomson
Use and misuse of process and outcome data in managing performance of acute medical care: avoiding institutional stigma.
Lancet 2004;363(9415):1147-54.
2004: Matthew R Sydes; David J Spiegelhalter; Douglas Altman; Abdel B Babiker; M K B Parmar
Systematic qualitative review of the literature on data monitoring committees for randomized controlled trials.
Clinical trials (London, England) 2004;1(1):60-79.
2004: Matthew R Sydes; Douglas Altman; Abdel B Babiker; M K B Parmar; David J Spiegelhalter
Reported use of data monitoring committees in the main published reports of randomized controlled trials: a cross-sectional study.
Clinical trials (London, England) 2004;1(1):48-59.
2004: Owen J Arthurs; C M E Stephenson; K Rice; V C Lupson; David J Spiegelhalter; Simon Boniface; Edward T Bullmore
Dopaminergic effects on electrophysiological and functional MRI measures of human cortical stimulus-response power laws.
NeuroImage 2004;21(2):540-6.
2003: David J Spiegelhalter; Nicola G Best
Bayesian approaches to multiple sources of evidence and uncertainty in complex cost-effectiveness modelling.
Statistics in medicine 2003;22(23):3687-709.
2003: E C Marshall; David J Spiegelhalter
Approximate cross-validatory predictive checks in disease mapping models.
Statistics in medicine 2003;22(10):1649-60.
2003: David J Spiegelhalter
Ranking institutions.
The Journal of thoracic and cardiovascular surgery 2003;125(5):1171-3; author reply 1173.
2003: Olivia Grigg; Vernon T Farewell; David J Spiegelhalter
Use of risk-adjusted CUSUM and RSPRT charts for monitoring in medical contexts.
Statistical methods in medical research 2003;12(2):147-70.
2003: David J Spiegelhalter; Olivia Grigg; Robin Kinsman; Tom Treasure
Risk-adjusted sequential probability ratio tests: applications to Bristol, Shipman and adult cardiac surgery.
International journal for quality in health care : journal of the International Society for Quality in Health Care / ISQua 2003;15(1):7-13.
2002: David J Spiegelhalter
Funnel plots for institutional comparison.
Quality & safety in health care 2002;11(4):390-1.
2002: David E Warn; Simon G Thompson; David J Spiegelhalter
Bayesian random effects meta-analysis of trials with binary outcomes: methods for the absolute risk difference and relative risk scales.
Statistics in medicine 2002;21(11):1601-23.
2002: David J Lunn; Nicky Best; Andrew Thomas; Jon Wakefield; David J Spiegelhalter
Bayesian analysis of population PK/PD models: general concepts and software.
Journal of pharmacokinetics and pharmacodynamics 2002;29(3):271-307.
2002: David J Spiegelhalter
Mortality and volume of cases in paediatric cardiac surgery: retrospective study based on routinely collected data.
BMJ (Clinical research ed.) 2002;324(7332):261-3.
2002: Julian P T Higgins; David J Spiegelhalter
Being sceptical about meta-analyses: a Bayesian perspective on magnesium trials in myocardial infarction.
International journal of epidemiology 2002;31(1):96-104.
2001: A Vail; J Hornbuckle; David J Spiegelhalter; James thornton
Prospective application of Bayesian monitoring and analysis in an "open" randomized clinical trial.
Statistics in medicine 2001;20(24):3777-87.
2001: M K B Parmar; Gareth O Griffiths; David J Spiegelhalter; Robert Souhami; Douglas Altman; E van der Scheuren
Monitoring of large randomised clinical trials: a new approach with Bayesian methods.
Lancet 2001;358(9279):375-81.
2001: Paul Aylin; B Alves; Nicky Best; Adrian Cook; Paul Elliott; S J Evans; A E Lawrence; Gordon D Murray; J Pollock; David J Spiegelhalter
Comparison of UK paediatric cardiac surgical performance by analysis of routinely collected data 1984-96: was Bristol an outlier?
Lancet 2001;358(9277):181-7.
2001: David J Spiegelhalter
Bayesian methods for cluster randomized trials with continuous responses.
Statistics in medicine 2001;20(3):435-52.
2001: Fawzia Hyland; Ann Louise Kinmonth; Theresa M Marteau; S Griffin; P Murrell; David J Spiegelhalter; C Todd; F Walter; B Berrington; M Bobrow; James Mackay
Raising concerns about family history of breast cancer in primary care consultations: prospective, population based study. Women's Concerns Study Group.
BMJ (Clinical research ed.) 2001;322(7277):27-8.
2000: M Campbell; R Fitzpatrick; A Haines; Ann Louise Kinmonth; Peter Sandercock; David J Spiegelhalter; Peter Tyrer
Framework for design and evaluation of complex interventions to improve health.
BMJ (Clinical research ed.) 2000;321(7262):694-6.
2000: David J Spiegelhalter; J P Myles; D R Jones; Keith Abrams
Bayesian methods in health technology assessment: a review.
Health technology assessment (Winchester, England) 2000;4(38):1-130.
1999: Carol Brayne; David J Spiegelhalter; Carole Dufouil; LY Chi; TR Dening; Eugene S Paykel; daniel o'connor; A Ahmed; MA McGee; Felicia A Huppert
Estimating the true extent of cognitive decline in the old old.
Journal of the American Geriatrics Society 1999;47(11):1283-8.
1999: Réjean Hébert; C Brayne; David J Spiegelhalter
Factors associated with functional decline and improvement in a very elderly community-dwelling population.
American journal of epidemiology 1999;150(5):501-10.
1999: David J Spiegelhalter; J P Myles; D R Jones; Keith Abrams
Methods in health service research. An introduction to bayesian methods in health technology assessment.
BMJ (Clinical research ed.) 1999;319(7208):508-12.
1999: TC Prevost; David J Spiegelhalter; Stephen W Duffy
Use of person-years of CIN III exposure as a surrogate outcome measure in cervical cancer screening trials.
Journal of epidemiology and biostatistics 1999;4(1):19-29.
1998: Chit Ming Wong; Tai Hing Lam; J Peters; Anthony J Hedley; S G Ong; A Y Tam; J Liu; David J Spiegelhalter
Comparison between two districts of the effects of an air pollution intervention on bronchial responsiveness in primary school children in Hong Kong.
Journal of epidemiology and community health 1998;52(9):571-8.
1998: J Wellwood; Mark J Sculpher; D Stoker; G J Nicholls; C Geddes; A Whitehead; R Singh; David J Spiegelhalter
Randomised controlled trial of laparoscopic versus open mesh repair for inguinal hernia: outcome and cost.
BMJ (Clinical research ed.) 1998;317(7151):103-10.
1998: E C Marshall; David J Spiegelhalter
Reliability of league tables of in vitro fertilisation clinics: retrospective analysis of live birth rates.
BMJ (Clinical research ed.) 1998;316(7146):1701-4; discussion 1705.
1997: Réjean Hébert; David J Spiegelhalter; C Brayne
Setting the minimal metrically detectable change on disability rating scales.
Archives of physical medicine and rehabilitation 1997;78(12):1305-8.
1997: K Bull; David J Spiegelhalter
Survival analysis in observational studies.
Statistics in medicine 1997;16(9):1041-74.
1997: Réjean Hébert; C Brayne; David J Spiegelhalter
Incidence of functional decline and improvement in a community-dwelling, very elderly population.
American journal of epidemiology 1997;145(10):935-44.
1997: L Gibson; David J Spiegelhalter; C Camilleri-Ferrante; Nicholas E Day
Trends in invasive cervical cancer incidence in East Anglia from 1971 to 1993.
Journal of medical screening 1997;4(1):44-8.
1996: N G Best; K K Tan; Andrew K Trull; David J Spiegelhalter; S Stewart; John Wallwork
Pharmacodynamics of cyclosporine in heart and heart-lung transplant recipients. II: Blood cyclosporine concentrations and other risk factors for lung allograft rejection.
Transplantation 1996;62(10):1436-41.
1996: N G Best; Andrew K Trull; K K Tan; David J Spiegelhalter; NR Cary; John Wallwork
Pharmacodynamics of cyclosporine in heart and heart-lung transplant recipients. I: Blood cyclosporine concentrations and other risk factors for cardiac allograft rejection.
Transplantation 1996;62(10):1429-35.
1996: Jean Peters; Anthony J Hedley; Chit Ming Wong; Tai Hing Lam; S G Ong; J Liu; David J Spiegelhalter
Effects of an ambient air pollution intervention and environmental tobacco smoke on children's respiratory health in Hong Kong.
International journal of epidemiology 1996;25(4):821-8.
1996: M Chiogna; David J Spiegelhalter; R C Franklin; K Bull
An empirical comparison of expert-derived and data-derived classification trees.
Statistics in medicine 1996;15(2):157-69.
1995: T C Smith; David J Spiegelhalter; A Thomas
Bayesian approaches to random-effects meta-analysis: a comparative study.
Statistics in medicine 1995;14(24):2685-99.
1995: N G Best; Andrew K Trull; K K Tan; David J Spiegelhalter; Tim Wreghitt; John Wallwork
Blood cyclosporine concentrations and cytomegalovirus infection following heart transplantation.
Transplantation 1995;60(7):689-94.
1995: K E Sorensen; David S Celermajer; David J Spiegelhalter; D Georgakopoulos; J Robinson; O Thomas; John E Deanfield
Non-invasive measurement of human endothelium dependent arterial responses: accuracy and reproducibility.
British heart journal 1995;74(3):247-53.
1995: N G Best; K K Tan; W R Gilks; David J Spiegelhalter
Estimation of population pharmacokinetics using the Gibbs sampler.
Journal of pharmacokinetics and biopharmaceutics 1995;23(4):407-35.
1995: Tom Smith; J D Charlwood; W Takken; Marcel Tanner; David J Spiegelhalter
Mapping the densities of malaria vectors within a single village.
Acta tropica 1995;59(1):1-18.
1995: K Bull; J Somerville; E Ty; David J Spiegelhalter
Presentation and attrition in complex pulmonary atresia.
Journal of the American College of Cardiology 1995;25(2):491-9.
1994: N G Best; K K Tan; Andrew K Trull; David J Spiegelhalter; K L Hue; Noreen Caine; John Wallwork
Design and evaluation of a computer tool to aid early management of cyclosporine therapy after heart and heart-lung transplantation.
Transplantation proceedings 1994;26(5):2716-7.
1994: J Grossman; M K Parmar; David J Spiegelhalter; L S Freedman
A unified method for monitoring and analysing controlled trials.
Statistics in medicine 1994;13(18):1815-26.
1994: David S Celermajer; K E Sorensen; David J Spiegelhalter; D Georgakopoulos; J Robinson; John E Deanfield
Aging is associated with endothelial dysfunction in healthy men years before the age-related decline in women.
Journal of the American College of Cardiology 1994;24(2):471-6.
1994: Laurence S Freedman; David J Spiegelhalter; M K Parmar
The what, why and how of Bayesian clinical trials monitoring.
Statistics in medicine 1994;13(13-14):1371-83; discussion 1385-9.
1994: M K B Parmar; David J Spiegelhalter; L S Freedman
The CHART trials: Bayesian design and monitoring in practice. CHART Steering Committee.
Statistics in medicine 1994;13(13-14):1297-312.
1994: A Theodossi; David J Spiegelhalter; J Jass; J Firth; M Dixon; M Leader; D A Levison; R Lindley; I Filipe; A Price
Observer variation and discriminatory value of biopsy features in inflammatory bowel disease.
Gut 1994;35(7):961-8.
1994: P Presbitero; J Somerville; S Stone; E Aruta; David J Spiegelhalter; F Rabajoli
Pregnancy in cyanotic congenital heart disease. Outcome of mother and fetus.
Circulation 1994;89(6):2673-6.
1994: D L Stoker; David J Spiegelhalter; R Singh; J M Wellwood
Laparoscopic versus open inguinal hernia repair: randomised prospective trial.
Lancet 1994;343(8908):1243-5.
1994: Marc R de Leval; K François; C Bull; W Brawn; David J Spiegelhalter
Analysis of a cluster of surgical failures. Application to a series of neonatal arterial switch operations.
The Journal of thoracic and cardiovascular surgery 1994;107(3):914-23; discussion 923-4.
1994: G P Crean; R J Holden; R P Knill-Jones; A D Beattie; W B James; F M Marjoribanks; David J Spiegelhalter
A database on dyspepsia.
Gut 1994;35(2):191-202.
1994: L W van Heurn; C M Wong; David J Spiegelhalter; K Sorensen; M R de Leval; J Stark; Martin Elliott
Surgical treatment of aortic coarctation in infants younger than three months: 1985 to 1990. Success of extended end-to-end arch aortoplasty.
The Journal of thoracic and cardiovascular surgery 1994;107(1):74-85; discussion 85-6.
1994: D S Celermajer; David J Spiegelhalter; M Deanfield; J E Deanfield
Variability of episodic ST segment depression in chronic stable angina: implications for individual and group trials of therapeutic efficacy.
Journal of the American College of Cardiology 1994;23(1):66-73.
1993: Tim Higenbottam; David J Spiegelhalter; J P Scott; V Fuster; Anh Tuan Dinh-Xuan; Noreen Caine; John Wallwork
Prostacyclin (epoprostenol) and heart-lung transplantation as treatments for severe pulmonary hypertension.
British heart journal 1993;70(4):366-70.
1993: A Fletcher; David J Spiegelhalter; J Staessen; Lutgarde Thijs; Christopher J Bulpitt
Implications for trials in progress of publication of positive results.
Lancet 1993;342(8872):653-7.
1993: David J Spiegelhalter; L S Freedman; M K Parmar
Applying Bayesian ideas in drug development and clinical trials.
Statistics in medicine 1993;12(15-16):1501-11; discussion 1513-7.
1993: R C Franklin; David J Spiegelhalter; I D Sullivan; Robert Henry Anderson; D G Thoele; E A Shinebourne; J E Deanfield
Tricuspid atresia presenting in infancy. Survival and suitability for the Fontan operation.
Circulation 1993;87(2):427-39.
1992: David J Spiegelhalter
Risk stratification for open heart surgery.
BMJ (Clinical research ed.) 1992;305(6867):1500.
1992: N G Best; Andrew K Trull; K K Tan; K L Hue; David J Spiegelhalter; S M Gore; John Wallwork
Blood cyclosporin concentrations and the short-term risk of lung rejection following heart-lung transplantation.
British journal of clinical pharmacology 1992;34(6):513-20.
1992: David J Spiegelhalter; SM Gore; R Fitzpatrick; A E Fletcher; D R Jones; D R Cox
Quality of life measures in health care. III: Resource allocation.
BMJ (Clinical research ed.) 1992;305(6863):1205-9.
1992: A Fletcher; S Gore; D Jones; R Fitzpatrick; David J Spiegelhalter; D Cox
Quality of life measures in health care. II: Design, analysis, and interpretation.
BMJ (Clinical research ed.) 1992;305(6862):1145-8.
1992: David S Celermajer; K E Sorensen; V M Gooch; David J Spiegelhalter; O I Miller; Ian D Sullivan; J K Lloyd; John E Deanfield
Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis.
Lancet 1992;340(8828):1111-5.
1992: Ray Fitzpatrick; A Fletcher; S Gore; D Jones; David J Spiegelhalter; D Cox
Quality of life measures in health care. I: Applications and issues in assessment.
BMJ (Clinical research ed.) 1992;305(6861):1074-7.
1992: S J Pocock; David J Spiegelhalter
Domiciliary thrombolysis by general practitioners.
BMJ (Clinical research ed.) 1992;305(6860):1015.
1992: Chit Ming Wong; David J Spiegelhalter
Effects of environment and passive smoking on the respiratory health of children.
International journal of epidemiology 1992;21(5):1031-2.
1992: A J Kirby; David J Spiegelhalter; Nicholas E Day; L Fenton; K Swanson; E M Mann; J E Macgregor
Conservative treatment of mild/moderate cervical dyskaryosis: long-term outcome.
Lancet 1992;339(8797):828-31.
1992: David S Celermajer; S Cullen; Ian D Sullivan; David J Spiegelhalter; R K Wyse; John E Deanfield
Outcome in neonates with Ebstein's anomaly.
Journal of the American College of Cardiology 1992;19(5):1041-6.
1992: Mark J Sculpher; Martin Buxton; B A Ferguson; David J Spiegelhalter; A J Kirby
Screening for diabetic retinopathy: a relative cost-effectiveness analysis of alternative modalities and strategies.
Health economics 1992;1(1):39-51.
1992: Laurence S Freedman; David J Spiegelhalter
Application of Bayesian statistics to decision making during a clinical trial.
Statistics in medicine 1992;11(1):23-35.
1992: J Wellwood; S Johannessen; David J Spiegelhalter
How does computer-aided diagnosis improve the management of acute abdominal pain?
Annals of the Royal College of Surgeons of England 1992;74(1):40-6.
1992: P Cooper; A J Kirby; David J Spiegelhalter; A L Whitehead; A Patterson
Management of women with a cervical smear showing a mild degree of dyskaryosis: a review of policy.
Cytopathology : official journal of the British Society for Clinical Cytology 1992;3(6):331-9.
1991: Mark J Sculpher; Martin Buxton; B A Ferguson; J E Humphreys; J F Altman; David J Spiegelhalter; A J Kirby; J S Jacob; H Bacon; S B Dudbridge
A relative cost-effectiveness analysis of different methods of screening for diabetic retinopathy.
Diabetic medicine : a journal of the British Diabetic Association 1991;8(7):644-50.
1991: R C Franklin; David J Spiegelhalter; R I Rossi Filho; F J Macartney; Robert Henry Anderson; M L Rigby; J E Deanfield
Double-inlet ventricle presenting in infancy. III. Outcome and potential for definitive repair.
The Journal of thoracic and cardiovascular surgery 1991;101(5):924-34.
1991: R C Franklin; David J Spiegelhalter; Robert Henry Anderson; F J Macartney; R I Rossi Filho; J M Douglas; M L Rigby; J E Deanfield
Double-inlet ventricle presenting in infancy. I. Survival without definitive repair.
The Journal of thoracic and cardiovascular surgery 1991;101(5):767-76.
1991: Martin Buxton; Mark J Sculpher; B A Ferguson; J E Humphreys; J F Altman; David J Spiegelhalter; A J Kirby; J S Jacob; H Bacon; S B Dudbridge
Screening for treatable diabetic retinopathy: a comparison of different methods.
Diabetic medicine : a journal of the British Diabetic Association 1991;8(4):371-7.
1991: R C Franklin; David J Spiegelhalter; Robert Henry Anderson; F J Macartney; R I Rossi Filho; M L Rigby; J E Deanfield
Double-inlet ventricle presenting in infancy. II. Results of palliative operations.
The Journal of thoracic and cardiovascular surgery 1991;101(5):917-23.
1991: R C Franklin; David J Spiegelhalter; F J Macartney; K Bull
Evaluation of a diagnostic algorithm for heart disease in neonates.
BMJ (Clinical research ed.) 1991;302(6782):935-9.
1991: Jeremy Wyatt; David J Spiegelhalter
Field trials of medical decision-aids: potential problems and solutions.
Proceedings / the ... Annual Symposium on Computer Application [sic] in Medical Care. Symposium on Computer Applications in Medical Care 1991;():3-7.
1990: J Wyatt; David J Spiegelhalter
Evaluating medical expert systems: what to test and how?
Medical informatics = Médecine et informatique 1990;15(3):205-17.
1990: J Wyatt; David J Spiegelhalter
Validation and testing of medical decision aids. Introduction.
Medical informatics = Médecine et informatique 1990;15(3):183-4.
1990: J E Deanfield; David J Spiegelhalter
Variability of myocardial ischemia: implications for monitoring strategies.
Advances in cardiology 1990;37():176-86.
1989: Laurence S Freedman; David J Spiegelhalter
Comparison of Bayesian with group sequential methods for monitoring clinical trials.
Controlled clinical trials 1989;10(4):357-67.
1989: R C Franklin; David J Spiegelhalter; F J Macartney; K Bull
Combining clinical judgement and statistical data in expert systems: over-the-telephone management decisions for critical congenital heart disease in the first month of life.
International journal of clinical monitoring and computing 1989;6(3):157-66.
1989: J M Wellwood; David J Spiegelhalter
Computers and the diagnosis of acute abdominal pain.
British journal of hospital medicine 1989;41(6):564-7.
1988: S Livesey; Noreen Caine; David J Spiegelhalter; T A English; J Wallwork
Cardiac surgery for patients aged 65 years and older: a long term survival analysis.
British heart journal 1988;60(6):480-4.
1988: M E Wilson; David J Spiegelhalter; J A Robertson; P Lesser
Predicting difficult intubation.
British journal of anaesthesia 1988;61(2):211-6.
1988: M Hakim; David J Spiegelhalter; T A English; Noreen Caine; John Wallwork
Cardiac transplantation with cyclosporine and steroids: medium and long-term results.
Transplantation proceedings 1988;20(3 Suppl 3):327-32.
1988: David J Spiegelhalter
Comparison of groups when outcomes are on an ordered scale.
Alimentary pharmacology & therapeutics 1988;2(1):41-2.
1988: David J Spiegelhalter
Statistical issues in studies of individual response.
Scandinavian journal of gastroenterology. Supplement 1988;147():40-5.
1988: David J Spiegelhalter; L S Freedman
A predictive approach to selecting the size of a clinical trial, based on subjective clinical opinion.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1988;111():195-206.
1988: S M Gore; A O Langlands; David J Spiegelhalter; H J Stewart
Treatment decisions in breast cancer.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1988;111():149-70.
1987: David J Spiegelhalter; G P Crean; R Holden; R P Knill-Jones
Taking a calculated risk: predictive scoring systems in dyspepsia.
Scandinavian journal of gastroenterology. Supplement 1987;128():152-60.
1986: M E Wilson; David J Spiegelhalter
Awareness during anaesthesia.
Lancet 1986;2(8519):1338.
1986: David J Spiegelhalter
Probabilistic prediction in patient management and clinical trials.
Statistics in medicine 1986;5(5):421-33.
1986: David J Spiegelhalter; L S Freedman; P R Blackburn
Monitoring clinical trials: conditional or predictive power?
Controlled clinical trials 1986;7(1):8-17.
1986: David J Spiegelhalter; L S Freedman
A predictive approach to selecting the size of a clinical trial, based on subjective clinical opinion.
Statistics in medicine 1986;5(1):1-13.
1985: P Maher; C M O'Toole; T G Wreghitt; David J Spiegelhalter; T A English
Cytomegalovirus infection in cardiac transplant recipients associated with chronic T cell subset ratio inversion with expansion of a Leu-7+ TS-C+ subset.
Clinical and experimental immunology 1985;62(3):515-24.
1985: C M O'Toole; P Maher; David J Spiegelhalter; J R Walker; P Stovin; John Wallwork; T A English
'Rejection or infection' predictive value of T-cell subject ratio, before and after heart transplantation.
The Journal of heart transplantation 1985;4(5):518-24.
1985: David J Spiegelhalter
Statistical methodology for evaluating gastrointestinal symptoms.
Clinics in gastroenterology 1985;14(3):489-515.
1985: M J Langman; T H McConnell; David J Spiegelhalter; R B McConnell
Changing patterns of coeliac disease frequency: an analysis of Coeliac Society membership records.
Gut 1985;26(2):175-8.
1985: James K Bowmaker; Gerald H Jacobs; David J Spiegelhalter; John D Mollon
Two types of trichromatic squirrel monkey share a pigment in the red-green spectral region.
Vision research 1985;25(12):1937-46.
1984: David J Spiegelhalter
Computer aided decision making in medicine.
British medical journal (Clinical research ed.) 1984;289(6445):567-8.
1984: A Theodossi; David J Spiegelhalter; I G McFarlane; R Williams
Doctors' attitudes to risk in difficult clinical decisions: application of decision analysis in hepatobiliary disease.
British medical journal (Clinical research ed.) 1984;289(6439):213-6.
1984: F Macartney; J Douglas; David J Spiegelhalter
To catheterise or not to catheterise? An approach based on decision theory.
British heart journal 1984;51(3):330-8.
1984: W I Card; R W Lucas; David J Spiegelhalter
The logical description of a disease class as a Boolean function with special reference to the irritable bowel syndrome.
Clinical science (London, England : 1979) 1984;66(3):307-15.
1983: A Theodossi; David J Spiegelhalter; B Portmann; A L Eddleston; R Williams
The value of clinical, biochemical, ultrasound and liver biopsy data in assessing patients with liver disease.
Liver 1983;3(5):315-26.
1983: M McGreevy; R F Mould; David J Spiegelhalter
Evaluation of medical and managerial priorities in resource allocation: bone marrow transplantation at Westminster Hospital.
The Hospital and health services review 1983;79(5):213-7.
1983: M J Langman; D Coggon; David J Spiegelhalter
Analgesic intake and the risk of acute upper gastrointestinal bleeding.
The American journal of medicine 1983;74(6A):79-82.
1983: David J Spiegelhalter
Evaluation of clinical decision-aids, with an application to a system for dyspepsia.
Statistics in medicine 1983;2(2):207-16.
1983: David J Spiegelhalter; P G Stovin
An analysis of repeated biopsies following cardiac transplantation.
Statistics in medicine 1983;2(1):33-40.
1982: David J Spiegelhalter
Comments on Lindberg's correction for the effects of observer variation on probabilistic diagnosis.
Methods of information in medicine 1982;21(3):114-6.
1982: D Coggon; M J Langman; David J Spiegelhalter
Aspirin, paracetamol, and haematemesis and melaena.
Gut 1982;23(4):340-4.
1982: G P Crean; W I Card; A D Beattie; R J Holden; W B James; R P Knill-Jones; R W Lucas; David J Spiegelhalter
"Ulcer--like dyspepsia".
Scandinavian journal of gastroenterology. Supplement 1982;79():9-15.
1981: A J Hedley; David J Spiegelhalter; S J Jones; P Clements
Thyroid disease and breast cancer.
Lancet 1981;1(8219):558.
1981: A J Hedley; S J Jones; David J Spiegelhalter; P Clements; P D Bewsher; J G Simpson; R D Weir
Breast cancer in thyroid disease: fact or fallacy?
Lancet 1981;1(8212):131-3.