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Markus Böhm

Research Profile

Chemicals & Drugs

Anatomy

Physiology

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Publications

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Agatha Stegemann; Adriana del Rey; Beate Eckes; Bernd L Fiebich; Sergei A Grando; Alexander Heinick; Thomas A Luger; Frank U Müller; Karin Scharffetter-Kochanek; Jan S Schulte; Anca Sindrilaru; Markus Böhm
Tropisetron suppresses collagen synthesis in skin fibroblasts via α7 nicotinic acetylcholine receptor and attenuates fibrosis in a scleroderma mouse model.
Markus Böhm; Susanne Grässel
Role of proopiomelanocortin-derived peptides and their receptors in the osteoarticular system: from basic to translational research.
Paraskevi Gkogkolou; Markus Böhm
Advanced glycation end products: Key players in skin aging?

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All Publications

2013: Agatha Stegemann; Adriana del Rey; Beate Eckes; Bernd L Fiebich; Sergei A Grando; Alexander Heinick; Thomas A Luger; Frank U Müller; Karin Scharffetter-Kochanek; Jan S Schulte; Anca Sindrilaru; Markus Böhm
Tropisetron suppresses collagen synthesis in skin fibroblasts via α7 nicotinic acetylcholine receptor and attenuates fibrosis in a scleroderma mouse model.
Arthritis and rheumatism 2013;65(3):792-804.
2012: Markus Böhm; Susanne Grässel
Role of proopiomelanocortin-derived peptides and their receptors in the osteoarticular system: from basic to translational research.
Endocrine reviews 2012;33(4):623-51.
2012: Paraskevi Gkogkolou; Markus Böhm
Advanced glycation end products: Key players in skin aging?
Dermato-endocrinology 2012;4(3):259-70.
2012: Markus Böhm; Thomas A Luger; Ulrike Raap; Rainer H Straub; Tomasz Wasiewicz; Michal A Zmijewski; Andrzej Slominski
KU812 basophils express urocortin, CRH-R, MC1R and steroidogenic enzymes and secrete progesterone.
Experimental dermatology 2012;21(7):541-3.
2012: Markus Böhm; Randolf Brehler; Britta Eiz-Vesper; Manuela Gehring; Helmut Haas; Kerstin Jurk; Alexander Kapp; Thomas A Luger; Ralf Paus; Evgeni Ponimaskin; Koji Sugawara; Andrew F Walls; Mara Apel; Ulrike Raap
Modulation of basophil activity: a novel function of the neuropeptide α-melanocyte-stimulating hormone.
The Journal of allergy and clinical immunology 2012;129(4):1085-93.
2011: Dominik Bettenworth; Markus Böhm; Thomas Brzoska; Marion Buyse; Isabel Czorniak; Wolfram Domschke; Klaus Kannengiesser; Torsten Kucharzik; Thomas A Luger; Christian Maaser; Rudolf Mennigen; Andreas Lügering
The tripeptide KdPT protects from intestinal inflammation and maintains intestinal barrier function.
The American journal of pathology 2011;179(3):1230-42.
2011: Andreas Voss; Günther Bode; Claudia Sopalla; Malgorzata Benedyk; Georg Varga; Markus Böhm; Wolfgang Nacken; Claus Kerkhoff
Expression of S100A8/A9 in HaCaT keratinocytes alters the rate of cell proliferation and differentiation.
FEBS letters 2011;585(2):440-6.
2010: Arianna Mastrofrancesco; Agatha Kokot; Alex Eberle; Nicholas C J Gibbons; Karin U Schallreuter; Elwira Strozyk; Mauro Picardo; Christos C Zouboulis; Thomas A Luger; Markus Böhm
KdPT, a tripeptide derivative of alpha-melanocyte-stimulating hormone, suppresses IL-1 beta-mediated cytokine expression and signaling in human sebocytes.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(3):1903-11.
2010: Annegret Kuhn; A M Meuth; D Bein; S Amler; Stefan Beissert; Markus Böhm; R Brehler; Jan Ehrchen; S Grundmann; M Haust; V Ruland; Meinhard Schiller; P Schulz; Sonja Ständer; Cristina Sauerland; W Köpcke; Thomas A Luger; Gisela Bonsmann
Revised Cutaneous Lupus Erythematosus Disease Area and Severity Index (RCLASI): a modified outcome instrument for cutaneous lupus erythematosus.
The British journal of dermatology 2010;163(1):83-92.
2010: Meinhard Schiller; Sylviane Dennler; Ulf Anderegg; Agatha Kokot; Jan C Simon; Thomas A Luger; Alain Mauviel; Markus Böhm
Increased cAMP levels modulate transforming growth factor-beta/Smad-induced expression of extracellular matrix components and other key fibroblast effector functions.
The Journal of biological chemistry 2010;285(1):409-21.
2009: Bettina Ramser; Agatha Kokot; Dieter Metze; Nina Weiss; Thomas A Luger; Markus Böhm
Hydroxychloroquine modulates metabolic activity and proliferation and induces autophagic cell death of human dermal fibroblasts.
The Journal of investigative dermatology 2009;129(10):2419-26.
2009: Agatha Kokot; Dieter Metze; Nicolas Mouchet; Marie-Dominique Galibert; Meinhard Schiller; Thomas A Luger; Markus Böhm
Alpha-melanocyte-stimulating hormone counteracts the suppressive effect of UVB on Nrf2 and Nrf-dependent gene expression in human skin.
Endocrinology 2009;150(7):3197-206.
2009: Markus Böhm
Neuroendocrine regulators: Novel trends in sebaceous gland research with future perspectives for the treatment of acne and related disorders.
Dermato-endocrinology 2009;1(3):136-40.
2009: Cord Sunderkötter; I Herrgott; C Brückner; P Moinzadeh; C Pfeiffer; Joachim Gerss; Nicolas Hunzelmann; Markus Böhm; Thomas Krieg; U Müller-Ladner; E Genth; E Schulze-Lohoff; Michael Meurer; I Melchers; G Riemekasten
Comparison of patients with and without digital ulcers in systemic sclerosis: detection of possible risk factors.
The British journal of dermatology 2009;160(4):835-43.
2009: Agatha Kokot; Anca Sindrilaru; Meinhard Schiller; Cord Sunderkötter; Claus Kerkhoff; Beate Eckes; Karin Scharffetter-Kochanek; Thomas A Luger; Markus Böhm
alpha-melanocyte-stimulating hormone suppresses bleomycin-induced collagen synthesis and reduces tissue fibrosis in a mouse model of scleroderma: melanocortin peptides as a novel treatment strategy for scleroderma?
Arthritis and rheumatism 2009;60(2):592-603.
2008: Gabriele Stengel; Dieter Metze; Bernd Dörflinger; Thomas A Luger; Markus Böhm
Treatment of extra-abdominal aggressive fibromatosis with pegylated interferon.
Journal of the American Academy of Dermatology 2008;59(2 Suppl 1):S7-9.
2008: Thomas Brzoska; Thomas A Luger; Christian Maaser; Christoph Abels; Markus Böhm
Alpha-melanocyte-stimulating hormone and related tripeptides: biochemistry, antiinflammatory and protective effects in vitro and in vivo, and future perspectives for the treatment of immune-mediated inflammatory diseases.
Endocrine reviews 2008;29(5):581-602.
2008: Markus Böhm; Thomas A Luger; Gisela Bonsmann
Disseminated giant molluscum contagiosum in a patient with idiopathic CD4+ lymphocytopenia. Successful eradication with systemic interferon.
Dermatology (Basel, Switzerland) 2008;217(3):196-8.
2007: Stefan Beissert; Thomas Werfel; Uta Frieling; Markus Böhm; Michael Sticherling; Rudolf Stadler; Detlef Zillikens; Berthold Rzany; Nicolas Hunzelmann; Michael Meurer; Harald Gollnick; Thomas Ruzicka; Hans Pillekamp; Volker Junghans; Gisela Bonsmann; Thomas A Luger
A comparison of oral methylprednisolone plus azathioprine or mycophenolate mofetil for the treatment of bullous pemphigoid.
Archives of dermatology 2007;143(12):1536-42.
2007: Thomas E Scholzen; Simone Koenig; Michaela Fastrich; Markus Böhm; Thomas A Luger
Terminating the stress: peripheral peptidolysis of proopiomelanocortin-derived regulatory hormones by the dermal microvascular endothelial cell extracellular peptidases neprilysin and angiotensin-converting enzyme.
Endocrinology 2007;148(6):2793-805.
2007: Markus Böhm; Thomas A Luger
Lichen planus responding to efalizumab.
Journal of the American Academy of Dermatology 2007;56(5 Suppl):S92-3.
2006: Stefan Beissert; Thomas Werfel; Uta Frieling; Markus Böhm; Michael Sticherling; Rudolf Stadler; Detlef Zillikens; Berthold Rzany; Nicolas Hunzelmann; Michael Meurer; Harald Gollnick; Thomas Ruzicka; Hans Pillekamp; Volker Junghans; Thomas A Luger
A comparison of oral methylprednisolone plus azathioprine or mycophenolate mofetil for the treatment of pemphigus.
Archives of dermatology 2006;142(11):1447-54.
2006: Markus Böhm; Thomas A Luger; Desmond J Tobin; José C García-Borrón
Melanocortin receptor ligands: new horizons for skin biology and clinical dermatology.
The Journal of investigative dermatology 2006;126(9):1966-75.
2006: Meinhard Schiller; Markus Böhm; Peter Hensen; Helge Riemann; Thomas A Luger; Dorothée Nashan
Dermatomyositis associated with malignant melanoma--a marker of poor prognosis?
Journal of the American Academy of Dermatology 2006;54(2):221-6.
2006: Markus Böhm; Meinhard Schiller; Thomas A Luger
Non-pigmentary actions of alpha-melanocyte-stimulating hormone--lessons from the cutaneous melanocortin system.
Cellular and molecular biology (Noisy-le-Grand, France) 2006;52(2):61-8.
2005: Markus Böhm; Mareike Eickelmann; Zhuo Li; Stefan W Schneider; Vinzenz Oji; Sven Diederichs; Gregory S Barsh; Annika Vogt; Karola Stieler; Ulrike Blume-Peytavi; Thomas A Luger
Detection of functionally active melanocortin receptors and evidence for an immunoregulatory activity of alpha-melanocyte-stimulating hormone in human dermal papilla cells.
Endocrinology 2005;146(11):4635-46.
2005: Carmen Loquai; Dieter Metze; Dorothée Nashan; Thomas A Luger; Markus Böhm
Confetti-like lesions with hyperkeratosis: a novel ultraviolet-induced hypomelanotic disorder?
The British journal of dermatology 2005;153(1):190-3.
2005: Markus Böhm; Ilka Wolff; Thomas E Scholzen; Samantha J Robinson; Eugene Healy; Thomas A Luger; Thomas Schwarz; Agatha Schwarz
alpha-Melanocyte-stimulating hormone protects from ultraviolet radiation-induced apoptosis and DNA damage.
The Journal of biological chemistry 2005;280(7):5795-802.
2004: Zhuo Li; Dieter Metze; Dorothea Nashan; Carsten Müller-Tidow; Hubert Serve; Christopher Poremba; Thomas A Luger; Markus Böhm
Expression of SOCS-1, suppressor of cytokine signalling-1, in human melanoma.
The Journal of investigative dermatology 2004;123(4):737-45.
2004: Markus Böhm; Michael Raghunath; Cord Sunderkötter; Meinhard Schiller; Sonja Ständer; Thomas Brzoska; Thomas Cauvet; Helgi B Schiöth; Thomas Schwarz; Thomas A Luger
Collagen metabolism is a novel target of the neuropeptide alpha-melanocyte-stimulating hormone.
The Journal of biological chemistry 2004;279(8):6959-66.
2004: Meinhard Schiller; Thomas Brzoska; Markus Böhm; Dieter Metze; Thomas E Scholzen; André Rougier; Thomas A Luger
Solar-simulated ultraviolet radiation-induced upregulation of the melanocortin-1 receptor, proopiomelanocortin, and alpha-melanocyte-stimulating hormone in human epidermis in vivo.
The Journal of investigative dermatology 2004;122(2):468-76.
2004: Markus Böhm; Thomas A Luger
Melanocortins in fibroblast biology--current update and future perspective for dermatology.
Experimental dermatology 2004;13 Suppl 4():16-21.
2003: Markus Böhm; Uta Frieling; Thomas A Luger; Gisela Bonsmann
Successful treatment of anogenital lichen sclerosus with topical tacrolimus.
Archives of dermatology 2003;139(7):922-4.
2003: Thomas A Luger; Thomas E Scholzen; Thomas Brzoska; Markus Böhm
New insights into the functions of alpha-MSH and related peptides in the immune system.
Annals of the New York Academy of Sciences 2003;994():133-40.
2003: Markus Böhm; Markus Gaubitz; Thomas A Luger; Dieter Metze; Gisela Bonsmann
Topical tacrolimus as a therapeutic adjunct in patients with cutaneous lupus erythematosus. A report of three cases.
Dermatology (Basel, Switzerland) 2003;207(4):381-5.
2002: Markus Böhm; Peter Fritz Schmidt; Bernd Lödding; Holger Uphoff; Gerald W Westermann; Thomas A Luger; Gisela Bonsmann; Dieter Metze
Cutaneous hyperpigmentation induced by doxycycline: histochemical and ultrastructural examination, laser microprobe mass analysis, and cathodoluminescence.
The American Journal of dermatopathology 2002;24(4):345-50.
2002: Markus Böhm; Meinhard Schiller; Sonja Ständer; Holger Seltmann; Zhuo Li; Thomas Brzoska; Dieter Metze; Helgi B Schiöth; Anna Skottner; Kristina Seiffert; Christos Zouboulis; Thomas A Luger
Evidence for expression of melanocortin-1 receptor in human sebocytes in vitro and in situ.
The Journal of investigative dermatology 2002;118(3):533-9.
2002: Sonja Ständer; Markus Böhm; Thomas Brzoska; Klaus-Peter Zimmer; Thomas Luger; Dieter Metze
Expression of melanocortin-1 receptor in normal, malformed and neoplastic skin glands and hair follicles.
Experimental dermatology 2002;11(1):42-51.
2002: Agatha Schwarz; Sonja Ständer; Mark Berneburg; Markus Böhm; Dagmar Kulms; Harry van Steeg; Karin Grosse-Heitmeyer; Jean Krutmann; Thomas Schwarz
Interleukin-12 suppresses ultraviolet radiation-induced apoptosis by inducing DNA repair.
Nature cell biology 2002;4(1):26-31.
2001: Meinhard Schiller; Michael Raghunath; Ulrich Kubitscheck; Thomas E Scholzen; T Fisbeck; Dieter Metze; Thomas A Luger; Markus Böhm
Human dermal fibroblasts express prohormone convertases 1 and 2 and produce proopiomelanocortin-derived peptides.
The Journal of investigative dermatology 2001;117(2):227-35.
2001: Markus Böhm; U Schulte; J O Funk; Michael Raghunath; Iris Behrmann; Marcin Kortylewski; Peter C Heinrich; Thorsten Kues; Thomas A Luger; Thomas Schwarz
Interleukin-6-resistant melanoma cells exhibit reduced activation of STAT3 and lack of inhibition of cyclin E-associated kinase activity.
The Journal of investigative dermatology 2001;117(1):132-40.
2001: Markus Böhm; Meinhard Schiller; Dorothée Nashan; R Stadler; Thomas A Luger; Dieter Metze
Diffuse melanosis arising from metastatic melanoma: pathogenetic function of elevated melanocyte peptide growth factors.
Journal of the American Academy of Dermatology 2001;44(5):747-54.
2000: Markus Böhm; Burkhard Riemann; Thomas A Luger; Gisela Bonsmann
Bilateral upper limb lymphoedema associated with psoriatic arthritis: a case report and review of the literature.
The British journal of dermatology 2000;143(6):1297-301.
2000: Thomas E Scholzen; DH Kalden; Thomas Brzoska; T Fisbeck; Michaela Fastrich; Meinhard Schiller; Markus Böhm; Thomas Schwarz; Cheryl A Armstrong; John C Ansel; Thomas A Luger
Expression of proopiomelanocortin peptides in human dermal microvascular endothelial cells: evidence for a regulation by ultraviolet light and interleukin-1.
The Journal of investigative dermatology 2000;115(6):1021-8.
2000: Markus Böhm; Thomas A Luger
The role of melanocortins in skin homeostasis.
Hormone research 2000;54(5-6):287-93.
1999: Gerald W Westermann; Markus Böhm; Gisela Bonsmann; Karl Heinz Rahn; Klaus Kisters
Chronic intoxication by doxycycline use for more than 12 years.
Journal of internal medicine 1999;246(6):591-2.
1999: Markus Böhm; Dieter Metze; U Schulte; Eva Becher; Thomas A Luger; Thomas Brzoska
Detection of melanocortin-1 receptor antigenicity on human skin cells in culture and in situ.
Experimental dermatology 1999;8(6):453-61.
1999: Markus Böhm; Thomas Brzoska; U Schulte; Meinhard Schiller; Ulrich Kubitscheck; Thomas A Luger
Characterization of a polyclonal antibody raised against the human melanocortin-1 receptor.
Annals of the New York Academy of Sciences 1999;885():372-82.
1999: Markus Böhm; U Schulte; H Kalden; Thomas A Luger
Alpha-melanocyte-stimulating hormone modulates activation of NF-kappa B and AP-1 and secretion of interleukin-8 in human dermal fibroblasts.
Annals of the New York Academy of Sciences 1999;885():277-86.
1999: Markus Böhm; Thomas A Luger; Dieter Metze
[Acanthosis nigricans associated with transitional cell carcinoma of the bladder--symptomatic treatment with calcipotriol].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 1999;50(8):593-6.
1999: Markus Böhm; Thomas A Luger; Gisela Bonsmann
Disseminated superficial actinic porokeratosis: treatment with topical tacalcitol.
Journal of the American Academy of Dermatology 1999;40(3):479-80.
1999: Markus Böhm; Thomas A Luger
Cutaneous neuroimmunomodulation: the proopiomelanocortin system. A New York Academy of Sciences Conference, September 11-13, 1998, Münster, Germany.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 1999;107(3):225-8.
1998: Markus Böhm; Thomas A Luger
The pilosebaceous unit is part of the skin immune system.
Dermatology (Basel, Switzerland) 1998;196(1):75-9.
1997: Meinhard Schiller; Dieter Metze; Markus Böhm
[Hypomelanosis guttata idiopathica].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 1997;48(9):662-5.
1997: Frank U Müller; Peter Bokník; Jörg Knapp; Hartmut Lüss; Joachim Neumann; U Vahlensieck; Markus Böhm; MC Deng; Hans H Scheld; Wilhelm Schmitz
Quantification of the cAMP response element binding protein in ventricular nuclear protein from failing and nonfailing human hearts.
Biochemical and biophysical research communications 1997;236(2):351-4.