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Ofer Spiegelstein

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Bogdan Wlodarczyk; Denise Hill; X Chris Le; Ofer Spiegelstein; Richard H Finnell
Arsenic urinary speciation in Mthfr deficient mice injected with sodium arsenate.
Henrik Birn; Ofer Spiegelstein; Erik I Christensen; Richard Finnell
Renal tubular reabsorption of folate mediated by folate binding protein 1.
Ofer Spiegelstein; Amy Gould; Bogdan Wlodarczyk; Marlene Tsie; Xiufen Lu; Chris Le; Aron Troen; Jacob Selhub; Jorge A Piedrahita; J Michael Salbaum; Claudia Kappen; Stepan Melnyk; Jill James; Richard Finnell
Developmental consequences of in utero sodium arsenate exposure in mice with folate transport deficiencies.

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All Publications

2012: Bogdan Wlodarczyk; Denise Hill; X Chris Le; Ofer Spiegelstein; Richard H Finnell
Arsenic urinary speciation in Mthfr deficient mice injected with sodium arsenate.
Toxicology letters 2012;215(3):214-8.
2005: Henrik Birn; Ofer Spiegelstein; Erik I Christensen; Richard Finnell
Renal tubular reabsorption of folate mediated by folate binding protein 1.
Journal of the American Society of Nephrology : JASN 2005;16(3):608-15.
2005: Ofer Spiegelstein; Amy Gould; Bogdan Wlodarczyk; Marlene Tsie; Xiufen Lu; Chris Le; Aron Troen; Jacob Selhub; Jorge A Piedrahita; J Michael Salbaum; Claudia Kappen; Stepan Melnyk; Jill James; Richard Finnell
Developmental consequences of in utero sodium arsenate exposure in mice with folate transport deficiencies.
Toxicology and applied pharmacology 2005;203(1):18-26.
2005: David W L Ma; Richard Finnell; Laurie A Davidson; Evelyn S Callaway; Ofer Spiegelstein; Jorge A Piedrahita; J Michael Salbaum; Claudia Kappen; Brad R Weeks; Jill James; Daniel Bozinov; Joanne R Lupton; Robert S Chapkin
Folate transport gene inactivation in mice increases sensitivity to colon carcinogenesis.
Cancer research 2005;65(3):887-97.
2005: Ofer Spiegelstein; Aron Troen; S Jill James; X Chris Le; Xiufen Lu; Stepan Melnyk; Jacob Selhub; Richard H Finnell
Effects of dietary folate intake and folate binding protein-2 (Folbp2) on urinary speciation of sodium arsenate in mice.
Environmental toxicology and pharmacology 2005;19(1):1-7.
2004: Ofer Spiegelstein; Laura E Mitchell; Michelle Merriweather; Ned J Wicker; Qiang Zhang; Edward J Lammer; Richard Finnell
Embryonic development of folate binding protein-1 (Folbp1) knockout mice: Effects of the chemical form, dose, and timing of maternal folate supplementation.
Developmental dynamics : an official publication of the American Association of Anatomists 2004;231(1):221-31.
2004: Ofer Spiegelstein; Robert M Cabrera; Daniel Bozinov; Bogdan Wlodarczyk; Richard Finnell
Folate-regulated changes in gene expression in the anterior neural tube of folate binding protein-1 (Folbp1)-deficient murine embryos.
Neurochemical research 2004;29(6):1105-12.
2003: Ofer Spiegelstein; Nithiananda Chatterjie; George Alexander; Richard Finnell
Teratogenicity of valproate conjugates with anticonvulsant activity in mice.
Epilepsy research 2003;57(2-3):145-52.
2003: Ofer Spiegelstein; Michelle Merriweather; Ned J Wicker; Richard Finnell
Valproate-induced neural tube defects in folate-binding protein-2 (Folbp2) knockout mice.
Birth defects research. Part A, Clinical and molecular teratology 2003;67(12):974-8.
2003: Ofer Spiegelstein; Xiufen Lu; X Chris Le; Aron Troen; Jacob Selhub; Stepan Melnyk; S Jill James; Richard Finnell
Effects of dietary folate intake and folate binding protein-1 (Folbp1) on urinary speciation of sodium arsenate in mice.
Toxicology letters 2003;145(2):167-74.
2003: Nina Isoherranen; Ofer Spiegelstein; Meir Bialer; Jing Zhang; Michelle Merriweather; Boris Yagen; Michael Roeder; Aleata A Triplett; Volker Schurig; Richard Finnell
Developmental outcome of levetiracetam, its major metabolite in humans, 2-pyrrolidinone N-butyric acid, and its enantiomer (R)-alpha-ethyl-oxo-pyrrolidine acetamide in a mouse model of teratogenicity.
Epilepsia 2003;44(10):1280-8.
2003: Sandra G Heil; Leo A J Kluijtmans; Ofer Spiegelstein; Richard Finnell; Hank J Blom
Gene-specific monitoring of T7-based RNA amplification by real-time quantitative PCR.
BioTechniques 2003;35(3):502-4, 506-8.
2003: Nina Isoherranen; Boris Yagen; Ofer Spiegelstein; Richard Finnell; Michelle Merriweather; José H Woodhead; Bogdan Wlodarczyk; H White; Meir Bialer
Anticonvulsant activity, teratogenicity and pharmacokinetics of novel valproyltaurinamide derivatives in mice.
British journal of pharmacology 2003;139(4):755-64.
2003: Nina Isoherranen; Boris Yagen; Ofer Spiegelstein; Amir Steinman; Richard Finnell; Meir Bialer
Gas chromatographic determination of novel valproyl taurinamide derivatives in mouse and dog plasma.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2003;788(1):125-36.
2003: Nina Isoherranen; Boris Yagen; José H Woodhead; Ofer Spiegelstein; Simcha Blotnik; Karen S Wilcox; Richard Finnell; Gregory D Bennett; H White; Meir Bialer
Characterization of the anticonvulsant profile and enantioselective pharmacokinetics of the chiral valproylamide propylisopropyl acetamide in rodents.
British journal of pharmacology 2003;138(4):602-13.
2003: Richard Finnell; Amy Gould; Ofer Spiegelstein
Pathobiology and genetics of neural tube defects.
Epilepsia 2003;44 Suppl 3():14-23.
2002: Richard Finnell; Ofer Spiegelstein; Bogdan Wlodarczyk; Aleata Triplett; Igor P Pogribny; Stepan Melnyk; Jill S James
DNA methylation in Folbp1 knockout mice supplemented with folic acid during gestation.
The Journal of nutrition 2002;132(8 Suppl):2457S-2461S.
2001: Bogdan Wlodarczyk; Ofer Spiegelstein; Janee Gelineau-van Waes; Roseann L Vorce; X Lu; C X Le; Richard Finnell
Arsenic-induced congenital malformations in genetically susceptible folate binding protein-2 knockout mice.
Toxicology and applied pharmacology 2001;177(3):238-46.
2000: James D Eudy; Ofer Spiegelstein; Robert C Barber; Bogdan Wlodarczyk; J Talbot; Richard Finnell
Identification and characterization of the human and mouse SLC19A3 gene: a novel member of the reduced folate family of micronutrient transporter genes.
Molecular genetics and metabolism 2000;71(4):581-90.
2000: Ofer Spiegelstein; James D Eudy; Richard Finnell
Identification of two putative novel folate receptor genes in humans and mouse.
Gene 2000;258(1-2):117-25.
2000: Ofer Spiegelstein; Boris Yagen; Gregory D Bennett; Richard Finnell; Simcha Blotnik; Meir Bialer
Stereoselective pharmacokinetic analysis of valnoctamide, a CNS-active chiral amide analogue of valproic acid, in dogs, rats, and mice.
Therapeutic drug monitoring 2000;22(5):574-81.
2000: Ofer Spiegelstein; D L Kroetz; René H Levy; Boris Yagen; S I Hurst; M Levi; Abdullah Haj-Yehia; Meir Bialer
Structure activity relationship of human microsomal epoxide hydrolase inhibition by amide and acid analogues of valproic acid.
Pharmaceutical research 2000;17(2):216-21.
1999: Ofer Spiegelstein; Boris Yagen; René H Levy; Richard Finnell; Gregory D Bennett; Michael Roeder; Volker Schurig; Meir Bialer
Stereoselective pharmacokinetics and pharmacodynamics of propylisopropyl acetamide, a CNS-active chiral amide analog of valproic acid.
Pharmaceutical research 1999;16(10):1582-8.
1999: Ofer Spiegelstein; Boris Yagen; Meir Bialer
Structure-pharmacokinetic-pharmacodynamic relationships of N-alkyl derivatives of the new antiepileptic drug valproyl glycinamide.
Epilepsia 1999;40(5):545-52.
1999: Ofer Spiegelstein; Meir Bialer; M Radatz; H Nau; Boris Yagen
Enantioselective synthesis and teratogenicity of propylisopropyl acetamide, a CNS-active chiral amide analogue of valproic acid.
Chirality 1999;11(8):645-50.
1997: Ofer Spiegelstein; Meir Bialer; Boris Yagen
Isolation of N,N-dialkylated derivatives of valproylglycinamide from dog plasma by active charcoal adsorption and their quantification by high-performance liquid chromatography.
Journal of chromatography. B, Biomedical sciences and applications 1997;698(1-2):195-200.