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Joshua Spin

Research Profile

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TOP 3
Sushma Reddy; Joshua M Spin; Mingming Zhao; Frandics P Chan; Giovanni Fajardo; Dong-Qing Hu; Ethan Katznelson; Rajesh Punn; Daniel Bernstein
Physiologic and molecular characterization of a murine model of right ventricular volume overload.
Nicholas J Leeper; Lars Maegdefessel; Clint L Miller; Gary K Owens; G-One Ahn; Ziad A Ali; D Ryan Anderson; Erica Berzin; Henry Cheng; Karen Cheng; Ronald L Dalman; Patricia E de Almeida; Kelly P Downing; Yoko Kojima; Kim E Kortekaas; Ramendra K Kundu; Soumajit Kundu; Maximilian Quertermous; Azad Raiesdana; Scott C Roberts; Eric E Schadt; Joshua M Spin; Ryuji Toh; Philip S Tsao; Joseph C Wu; Baohui Xu; Thomas Quertermous
Loss of CDKN2B promotes p53-dependent smooth muscle cell apoptosis and aneurysm formation.
Joshua M Spin; Lars Maegdefessel; Philip S Tsao
Vascular smooth muscle cell phenotypic plasticity: focus on chromatin remodelling.

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All Publications

2013: Sushma Reddy; Joshua M Spin; Mingming Zhao; Frandics P Chan; Giovanni Fajardo; Dong-Qing Hu; Ethan Katznelson; Rajesh Punn; Daniel Bernstein
Physiologic and molecular characterization of a murine model of right ventricular volume overload.
American journal of physiology. Heart and circulatory physiology 2013;304(10):H1314-27.
2013: Nicholas J Leeper; Lars Maegdefessel; Clint L Miller; Gary K Owens; G-One Ahn; Ziad A Ali; D Ryan Anderson; Erica Berzin; Henry Cheng; Karen Cheng; Ronald L Dalman; Patricia E de Almeida; Kelly P Downing; Yoko Kojima; Kim E Kortekaas; Ramendra K Kundu; Soumajit Kundu; Maximilian Quertermous; Azad Raiesdana; Scott C Roberts; Eric E Schadt; Joshua M Spin; Ryuji Toh; Philip S Tsao; Joseph C Wu; Baohui Xu; Thomas Quertermous
Loss of CDKN2B promotes p53-dependent smooth muscle cell apoptosis and aneurysm formation.
Arteriosclerosis, thrombosis, and vascular biology 2013;33(1):e1-e10.
2012: Joshua M Spin; Lars Maegdefessel; Philip S Tsao
Vascular smooth muscle cell phenotypic plasticity: focus on chromatin remodelling.
Cardiovascular research 2012;95(2):147-55.
2012: Lars Maegdefessel; Michael V McConnell; Denis R Merk; Uwe Raaz; Azad Raiesdana; Anke M Schoelmerich; Joshua M Spin; Ryuji Toh; Junya Azuma; Ronald L Dalman; Alicia Deng; Nicholas J Leeper; Philip S Tsao
MicroRNA-21 blocks abdominal aortic aneurysm development and nicotine-augmented expansion.
Science translational medicine 2012;4(122):122ra22.
2012: Lars Maegdefessel; Michael V McConnell; Denis R Merk; Uwe Raaz; Azad Raiesdana; Anke M Schoelmerich; Joshua M Spin; Ryuji Toh; Junya Azuma; Jocelyn T Chin; Ronald L Dalman; Alicia Deng; Nicholas J Leeper; Philip S Tsao
Inhibition of microRNA-29b reduces murine abdominal aortic aneurysm development.
The Journal of clinical investigation 2012;122(2):497-506.
2012: Denis R Merk; Miquell O Miller; Friedrich W Mohr; Robert C Robbins; Joshua M Spin; Philip S Tsao; Cristina M Alvira; Gerald J Berry; Jocelyn T Chin; Benjamin A Dake; Cristiana Iosef; Naoyuki Kimura; Lars Maegdefessel; Michael P Fischbein
miR-29b participates in early aneurysm development in Marfan syndrome.
Circulation research 2012;110(2):312-24.
2011: Mingming Zhao; Andrew Connolly; Giovanni Fajardo; Diem Huynh; Sara Poorfarahani; Thomas Quertermous; Viswanathan Rajagopalan; Joshua M Spin; Takashi Urashima; Daniel Bernstein
Cardiac pressure overload hypertrophy is differentially regulated by β-adrenergic receptor subtypes.
American journal of physiology. Heart and circulatory physiology 2011;301(4):H1461-70.
2011: Joshua M Spin; Maureen M Tedesco; Junya Azuma; Ronald L Dalman; Alicia Deng; Justin S Dyer; Mark Hsu; Lars Maegdefessel; Philip S Tsao
Transcriptional profiling and network analysis of the murine angiotensin II-induced abdominal aortic aneurysm.
Physiological genomics 2011;43(17):993-1003.
2011: Nicholas J Leeper; Azad Raiesdana; Yoko Kojima; Hyung J Chun; Junya Azuma; Lars Maegdefessel; Ramendra K Kundu; Thomas Quertermous; Philip S Tsao; Joshua M Spin
MicroRNA-26a is a novel regulator of vascular smooth muscle cell function.
Journal of cellular physiology 2011;226(4):1035-43.
2011: Joshua M Spin
Gene mutations and familial thoracic aortic aneurysms: a walk on the mild side.
Circulation. Cardiovascular genetics 2011;4(1):4-6.
2010: Jessica Q Zhou; Francois Haddad; Jennifer A Tremmel; Joshua M Spin
A big man with a broken heart: stress-induced cardiomyopathy in a morbidly obese man.
Mayo Clinic proceedings. Mayo Clinic 2010;85(9):864-5.
2010: Joshua M Spin; Thomas Quertermous; Philip S Tsao
Chromatin remodeling pathways in smooth muscle cell differentiation, and evidence for an integral role for p300.
PloS one 2010;5(12):e14301.
2010: Lars Maegdefessel; Joshua M Spin; Junya Azuma; Philip S Tsao
New options with dabigatran etexilate in anticoagulant therapy.
Vascular health and risk management 2010;6():339-49.
2009: Maureen M Tedesco; Masahiro Terashima; Francis G Blankenberg; Zoia Levashova; Joshua M Spin; Marina V Backer; Joseph M Backer; Mien Sho; Eiketsu Sho; Michael V McConnell; Ronald L Dalman
Analysis of in situ and ex vivo vascular endothelial growth factor receptor expression during experimental aortic aneurysm progression.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(10):1452-7.
2007: Euan Ashley; Joshua M Spin; Raymond Tabibiazar; Thomas Quertermous
Frontiers in nephrology: genomic approaches to understanding the molecular basis of atherosclerosis.
Journal of the American Society of Nephrology : JASN 2007;18(11):2853-62.
2006: Euan Ashley; Rossella Ferrara; Jennifer Y King; Aditya Vailaya; Allan Kuchinsky; Xuanmin He; Blake Byers; Ulrich Gerckens; Stefan Oblin; Anya Tsalenko; Angela Soito; Joshua M Spin; Raymond Tabibiazar; Andrew J Connolly; John B Simpson; Eberhard Grube; Thomas Quertermous
Network analysis of human in-stent restenosis.
Circulation 2006;114(24):2644-54.
2006: David Xing-Fei Deng; Joshua M Spin; Anya Tsalenko; Aditya Vailaya; Amir Ben-Dor; Zohar Yakhini; Phil Tsao; Laurakay Bruhn; Thomas Quertermous
Molecular signatures determining coronary artery and saphenous vein smooth muscle cell phenotypes: distinct responses to stimuli.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(5):1058-65.
2006: Joseph C Wu; Joshua M Spin; Feng Cao; Shuan Lin; Xiaoyan Xie; Olivier Gheysens; Ian Y Chen; Ahmad Y Sheikh; Robert C Robbins; Anya Tsalenko; Sanjiv S Gambhir; Thomas Quertermous
Transcriptional profiling of reporter genes used for molecular imaging of embryonic stem cell transplantation.
Physiological genomics 2006;25(1):29-38.
2005: Jennifer Y King; Rossella Ferrara; Raymond Tabibiazar; Joshua M Spin; Mary M Chen; Allan Kuchinsky; Aditya Vailaya; Robert Kincaid; Anya Tsalenko; David Xing-Fei Deng; Andrew Connolly; Peng Zhang; Eugene Yang; Clifton Watt; Zohar Yakhini; Amir Ben-Dor; Annette Adler; Laurakay Bruhn; Philip Tsao; Thomas Quertermous; Euan Ashley
Pathway analysis of coronary atherosclerosis.
Physiological genomics 2005;23(1):103-18.
2005: Raymond Tabibiazar; Roger A Wagner; Euan Ashley; Jennifer Y King; Rossella Ferrara; Joshua M Spin; David A Sanan; Balasubramanian Narasimhan; Robert Tibshirani; Philip S Tsao; Bradley Efron; Thomas Quertermous
Signature patterns of gene expression in mouse atherosclerosis and their correlation to human coronary disease.
Physiological genomics 2005;22(2):213-26.
2005: Raymond Tabibiazar; Roger A Wagner; Joshua M Spin; Euan Ashley; Balasubramanian Narasimhan; Edward M Rubin; Bradley Efron; Philip S Tsao; Robert Tibshirani; Thomas Quertermous
Mouse strain-specific differences in vascular wall gene expression and their relationship to vascular disease.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(2):302-8.
2004: Joshua M Spin; Shriram Nallamshetty; Raymond Tabibiazar; Euan Ashley; Jennifer Y King; Mary Chen; Philip S Tsao; Thomas Quertermous
Transcriptional profiling of in vitro smooth muscle cell differentiation identifies specific patterns of gene and pathway activation.
Physiological genomics 2004;19(3):292-302.
2004: Tatsuro Ishida; Sungshin Y Choi; Ramendra K Kundu; Joshua M Spin; Tomoya Yamashita; Ken-ichi Hirata; Yoko Kojima; Mitsuhiro Yokoyama; Allen D Cooper; Thomas Quertermous
Endothelial lipase modulates susceptibility to atherosclerosis in apolipoprotein-E-deficient mice.
The Journal of biological chemistry 2004;279(43):45085-92.
2004: Steve Lai; Amir Kaykha; Takuya Yamazaki; Mary Goldstein; Joshua M Spin; Jonathan Myers; Victor F Froelicher
Treadmill scores in elderly men.
Journal of the American College of Cardiology 2004;43(4):606-15.
2003: Saad Shaikh; Naazli Shaikh; Sung H Chun; Joshua M Spin; Mark S Blumenkranz; Michael F Marmor
Retinal evaluation of patients on chronic amiodarone therapy.
Retina (Philadelphia, Pa.) 2003;23(3):354-9.
2003: Joshua M Spin; Randall H Vagelos
Early use of statins in acute coronary syndromes.
Current atherosclerosis reports 2003;5(1):44-51.
2002: Joshua M Spin; Randall H Vagelos
Early use of statins in acute coronary syndromes.
Current cardiology reports 2002;4(4):289-97.
2002: Joshua M Spin; Manish Prakash; Victor F Froelicher; Sara Partington; Rachel Marcus; Dat Do; Jonathan Myers
The prognostic value of exercise testing in elderly men.
The American journal of medicine 2002;112(6):453-9.
1999: Joshua M Spin
Abnormal ECG after extensive maxillofacial surgery.
Hospital practice (1995) 1999;34(11):27-8.