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Francis Spinale

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Living Beings

Swine
Dogs

Anatomy

Disorders

Physiology

Chemicals & Drugs

Activities & Behaviors

Artificial Cardiac Pacing

Procedures

Induced Heart Arrest

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Co-Publications
Name
106
Mukherjee, Rupak
80
Crawford, Fred
38
Zile, Michael
34
Stroud, Robert
34
Hendrick, Jennifer
30
Zellner, James
28
Dorman, Hugh
25
Ikonomidis, John
24
Clair, MJ
23
Hebbar, Latha
18
Carabello, Blase
16
Krombach, Stephen
16
Sample, Jeffrey
15
McLean, Julie
15
Kribbs, SB

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Publications

TOP 3
Mani Santhosh K; Balasubramanian Sundaravadivel; Zavadzkas Juozas A; Jeffords Laura B; Rivers William T; Zile Michael R; Mukherjee Rupak; Spinale Francis G; Kuppuswamy Dhandapani
Calpain inhibition preserves myocardial structure and function following myocardial infarction.
Jones Jeffrey A; Beck Christy; Barbour John R; Zavadzkas Jouzas A; Mukherjee Rupak; Spinale Francis G; Ikonomidis John S
Alterations in aortic cellular constituents during thoracic aortic aneurysm development: myofibroblast-mediated vascular remodeling.
Ruddy Jean Marie; Jones Jeffrey A; Stroud Robert E; Mukherjee Rupak; Spinale Francis G; Ikonomidis John S
Differential effects of mechanical and biological stimuli on matrix metalloproteinase promoter activation in the thoracic aorta.

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All Publications

2009: Mani Santhosh K; Balasubramanian Sundaravadivel; Zavadzkas Juozas A; Jeffords Laura B; Rivers William T; Zile Michael R; Mukherjee Rupak; Spinale Francis G; Kuppuswamy Dhandapani
Calpain inhibition preserves myocardial structure and function following myocardial infarction.
American journal of physiology. Heart and circulatory physiology 2009;297(5):H1744-51.
2009: Jones Jeffrey A; Beck Christy; Barbour John R; Zavadzkas Jouzas A; Mukherjee Rupak; Spinale Francis G; Ikonomidis John S
Alterations in aortic cellular constituents during thoracic aortic aneurysm development: myofibroblast-mediated vascular remodeling.
The American journal of pathology 2009;175(4):1746-56.
2009: Ruddy Jean Marie; Jones Jeffrey A; Stroud Robert E; Mukherjee Rupak; Spinale Francis G; Ikonomidis John S
Differential effects of mechanical and biological stimuli on matrix metalloproteinase promoter activation in the thoracic aorta.
Circulation 2009;120(11 Suppl):S262-8.
2009: Dixon Jennifer A; Gorman Robert C; Stroud Robert E; Bouges Shenikqua; Hirotsugu Hamamoto; Gorman Joseph H; Martens Timothy P; Itescu Silviu; Schuster Michael D; Plappert Theodore; St John-Sutton Martin G; Spinale Francis G
Mesenchymal cell transplantation and myocardial remodeling after myocardial infarction.
Circulation 2009;120(11 Suppl):S220-9.
2009: Spinale Francis G; Wilbur Nikole M
Matrix metalloproteinase therapy in heart failure.
Current treatment options in cardiovascular medicine 2009;11(4):339-46.
2009: Spinale Francis G; Escobar G Patricia; Mukherjee Rupak; Zavadzkas Juozas A; Saunders Stuart M; Jeffords Laura B; Leone Allyson M; Beck Christy; Bouges Shenikqua; Stroud Robert E
Cardiac-restricted overexpression of membrane type-1 matrix metalloproteinase in mice: effects on myocardial remodeling with aging.
Circulation. Heart failure 2009;2(4):351-60.
2009: Dixon Jennifer A; Spinale Francis G
Large animal models of heart failure: a critical link in the translation of basic science to clinical practice.
Circulation. Heart failure 2009;2(3):262-71.
2009: McEvoy Matthew D; Sabbagh Michel J; Taylor Anna Greta; Zavadzkas Juozas A; Koval Christine N; Stroud Robert E; Ford Rachael L; McLean Julie E; Reeves Scott T; Mukherjee Rupak; Spinale Francis G
Aprotinin modifies left ventricular contractility and cytokine release after ischemia-reperfusion in a dose-dependent manner in a murine model.
Anesthesia and analgesia 2009;108(2):399-406.
2009: Jones Jeffrey A; Spinale Francis G; Ikonomidis John S
Transforming growth factor-beta signaling in thoracic aortic aneurysm development: a paradox in pathogenesis.
Journal of vascular research 2009;46(2):119-37.
2008: Ford Rachael L; Mains Ira M; Hilton Ebony J; Reeves Scott T; Stroud Robert E; Crawford Fred A; Ikonomidis John S; Spinale Francis G
Endothelin-A receptor inhibition after cardiopulmonary bypass: cytokines and receptor activation.
The Annals of thoracic surgery 2008;86(5):1576-83.
2008: Ruddy Jean Marie; Jones Jeffrey A; Spinale Francis G; Ikonomidis John S
Regional heterogeneity within the aorta: relevance to aneurysm disease.
The Journal of thoracic and cardiovascular surgery 2008;136(5):1123-30.
2008: Sabbagh Michel J; Looper J Michael; Zavadzkas Juozas A; Stroud Robert E; Ford Rachael L; Rivers William T; Koval Christine N; McEvoy Matthew D; Reeves Scott T; Spinale Francis G
Aprotinin exacerbates left ventricular dysfunction after ischemia/reperfusion in mice lacking tumor necrosis factor receptor I.
Journal of cardiovascular pharmacology 2008;52(4):355-62.
2008: Mukherjee Rupak; Zavadzkas Juozas A; Saunders Stuart M; McLean Julie E; Jeffords Laura B; Beck Christy; Stroud Robert E; Leone Allyson M; Koval Christine N; Rivers William T; Basu Shubhayu; Sheehy Alexander; Michal Gene; Spinale Francis G
Targeted myocardial microinjections of a biocomposite material reduces infarct expansion in pigs.
The Annals of thoracic surgery 2008;86(4):1268-76.
2008: Zavadzkas Juozas A; Plyler Rebecca A; Bouges Shenikqua; Koval Christine N; Rivers William T; Beck Christy U; Chang Eileen I; Stroud Robert E; Mukherjee Rupak; Spinale Francis G
Cardiac-restricted overexpression of extracellular matrix metalloproteinase inducer causes myocardial remodeling and dysfunction in aging mice.
American journal of physiology. Heart and circulatory physiology 2008;295(4):H1394-402.
2008: Spinale Francis G; Koval Christine N; Deschamps Anne M; Stroud Robert E; Ikonomidis John S
Dynamic changes in matrix metalloprotienase activity within the human myocardial interstitium during myocardial arrest and reperfusion.
Circulation 2008;118(14 Suppl):S16-23.
2008: McEvoy Matthew D; Taylor Anna-Greta; Zavadzkas Juozas A; Mains Ira M; Ford Rachael L; Stroud Robert E; Jeffords Laura B; Beck Christy U; Reeves Scott T; Spinale Francis G
Aprotinin exerts differential and dose-dependent effects on myocardial contractility, oxidative stress, and cytokine release after ischemia-reperfusion.
The Annals of thoracic surgery 2008;86(2):568-75.
2008: Dorman Bruce H; Stroud Robert E; Wyckoff Michael M; Zellner James L; Botta Don; Leonardi Amy H; Ikonomidis John S; Spinale Francis G
Differential effects of epsilon-aminocaproic acid and aprotinin on matrix metalloproteinase release in patients following cardiopulmonary bypass.
Journal of cardiovascular pharmacology 2008;51(4):418-23.
2008: Haddad Georges E; Saunders Lori J; Crosby Seth D; Carles Maria; del Monte Federica; King Kindra; Bristow Michael R; Spinale Francis G; Macgillivray Thomas E; Semigran Marc J; Dec G William; Williams Steven A; Hajjar Roger J; Gwathmey Judith K
Human cardiac-specific cDNA array for idiopathic dilated cardiomyopathy: sex-related differences.
Physiological genomics 2008;33(2):267-77.
2008: Yan Andrew T; Yan Raymond T; Spinale Francis G; Afzal Rizwan; Gunasinghe Himali R; Stroud Robert E; McKelvie Robert S; Liu Peter P
Relationships between plasma levels of matrix metalloproteinases and neurohormonal profile in patients with heart failure.
European journal of heart failure : journal of the Working Group on Heart Failure of the European Society of Cardiology 2008;10(2):125-8.
2008: Deschamps Anne M; Zavadzkas Juozas; Murphy Rebecca L; Koval Christine N; McLean Julie E; Jeffords Laura; Saunders Stuart M; Sheats Nina J; Stroud Robert E; Spinale Francis G
Interruption of endothelin signaling modifies membrane type 1 matrix metalloproteinase activity during ischemia and reperfusion.
American journal of physiology. Heart and circulatory physiology 2008;294(2):H875-83.
2008: Beeri Ronen; Yosefy Chaim; Guerrero J Luis; Nesta Francesca; Abedat Suzan; Chaput Miguel; del Monte Federica; Handschumacher Mark D; Stroud Robert; Sullivan Suzanne; Pugatsch Thea; Gilon Dan; Vlahakes Gus J; Spinale Francis G; Hajjar Roger J; Levine Robert A
Mitral regurgitation augments post-myocardial infarction remodeling failure of hypertrophic compensation.
Journal of the American College of Cardiology 2008;51(4):476-86.
2008: Jones Jeffrey A; Barbour John R; Stroud Robert E; Bouges Shenikqua; Stephens Shelly L; Spinale Francis G; Ikonomidis John S
Altered transforming growth factor-beta signaling in a murine model of thoracic aortic aneurysm.
Journal of vascular research 2008;45(6):457-68.
2007: Spinale Francis G
Myocardial matrix remodeling and the matrix metalloproteinases: influence on cardiac form and function.
Physiological reviews 2007;87(4):1285-342.
2007: McEvoy Matthew D; Reeves Scott T; Reves J G; Spinale Francis G
Aprotinin in cardiac surgery: a review of conventional and novel mechanisms of action.
Anesthesia and analgesia 2007;105(4):949-62.
2007: Spruill Laura S; Lowry Abigail S; Stroud Robert E; Squires Christina E; Mains Ira M; Flack English C; Beck Christy; Ikonomidis John S; Crumbley A Jackson; McDermott Paul J; Spinale Francis G
Membrane-type-1 matrix metalloproteinase transcription and translation in myocardial fibroblasts from patients with normal left ventricular function and from patients with cardiomyopathy.
American journal of physiology. Cell physiology 2007;293(4):C1362-73.
2007: Beeri Ronen; Yosefy Chaim; Guerrero J Luis; Abedat Suzan; Handschumacher Mark D; Stroud Robert E; Sullivan Suzanne; Chaput Miguel; Gilon Dan; Vlahakes Gus J; Spinale Francis G; Hajjar Roger J; Levine Robert A
Early repair of moderate ischemic mitral regurgitation reverses left ventricular remodeling: a functional and molecular study.
Circulation 2007;116(11 Suppl):I288-93.
2007: Bonnema D Dirk; Webb Carson S; Pennington Weems R; Stroud Robert E; Leonardi Amy E; Clark Leslie L; McClure Catherine D; Finklea Laura; Spinale Francis G; Zile Michael R
Effects of age on plasma matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinases (TIMPs).
Journal of cardiac failure 2007;13(7):530-40.
2007: Ikonomidis John S; Hilton Ebony J; Payne Kimberly; Harrell April; Finklea Laura; Clark Leslie; Reeves Scott; Stroud Robert E; Leonardi Amy; Crawford Fred A; Spinale Francis G
Selective endothelin-A receptor inhibition after cardiac surgery: a safety and feasibility study.
The Annals of thoracic surgery 2007;83(6):2153-60; discussion 2161.
2007: Barbour John R; Spinale Francis G; Ikonomidis John S
Proteinase systems and thoracic aortic aneurysm progression.
The Journal of surgical research 2007;139(2):292-307.
2007: Ikonomidis John S; Jones Jeffery A; Barbour John R; Stroud Robert E; Clark Leslie L; Kaplan Brooke S; Zeeshan Ahmed; Bavaria Joseph E; Gorman Joseph H; Spinale Francis G; Gorman Robert C
Expression of matrix metalloproteinases and endogenous inhibitors within ascending aortic aneurysms of patients with bicuspid or tricuspid aortic valves.
The Journal of thoracic and cardiovascular surgery 2007;133(4):1028-36.
2006: Mukherjee Rupak; Mingoia Joseph T; Bruce James A; Austin Jeffrey S; Stroud Robert E; Escobar G Patricia; McClister David M; Allen Claire M; Alfonso-Jaume Maria A; Fini M Elizabeth; Lovett David H; Spinale Francis G
Selective spatiotemporal induction of matrix metalloproteinase-2 and matrix metalloproteinase-9 transcription after myocardial infarction.
American journal of physiology. Heart and circulatory physiology 2006;291(5):H2216-28.
2006: Barbour John R; Stroud Robert E; Lowry Abigail S; Clark Leslie L; Leone Allyson M; Jones Jeffery A; Spinale Francis G; Ikonomidis John S
Temporal disparity in the induction of matrix metalloproteinases and tissue inhibitors of metalloproteinases after thoracic aortic aneurysm formation.
The Journal of thoracic and cardiovascular surgery 2006;132(4):788-95.
2006: Yan Andrew T; Yan Raymond T; Spinale Francis G; Afzal Rizwan; Gunasinghe Himali R; Arnold Malcolm; Demers Catherine; McKelvie Robert S; Liu Peter P
Plasma matrix metalloproteinase-9 level is correlated with left ventricular volumes and ejection fraction in patients with heart failure.
Journal of cardiac failure 2006;12(7):514-9.
2006: Webb Carson S; Bonnema David D; Ahmed S Hinan; Leonardi Amy H; McClure Catherine D; Clark Leslie L; Stroud Robert E; Corn William C; Finklea Laura; Zile Michael R; Spinale Francis G
Specific temporal profile of matrix metalloproteinase release occurs in patients after myocardial infarction: relation to left ventricular remodeling.
Circulation 2006;114(10):1020-7.
2006: Spinale Francis G; Escobar G Patricia; Hendrick Jennifer W; Clark Leslie L; Camens Sarah S; Mingoia Joseph P; Squires Christina G; Stroud Robert E; Ikonomidis John S
Chronic matrix metalloproteinase inhibition following myocardial infarction in mice: differential effects on short and long-term survival.
The Journal of pharmacology and experimental therapeutics 2006;318(3):966-73.
2006: Apple Kimberly A; McLean Julie E; Squires Christina E; Schaeffer Brooke; Sample Jeffrey A; Murphy Rebecca L; Deschamps Anne M; Leonardi Amy H; Allen Claire M; Hendrick Jennifer W; Stroud Robert E; Mukherjee Rupak; Spinale Francis G
Differential effects of protein kinase C isoform activation in endothelin-mediated myocyte contractile dysfunction with cardioplegic arrest and reperfusion.
The Annals of thoracic surgery 2006;82(2):664-71.
2006: Ikonomidis John S; Jones Jeffery A; Barbour John R; Stroud Robert E; Clark Leslie L; Kaplan Brooke S; Zeeshan Ahmed; Bavaria Joseph E; Gorman Joseph H; Spinale Francis G; Gorman Robert C
Expression of matrix metalloproteinases and endogenous inhibitors within ascending aortic aneurysms of patients with Marfan syndrome.
Circulation 2006;114(1 Suppl):I365-70.
2006: Mukherjee Rupak; Apple Kimberly A; Squires Christina E; Kaplan Brooke S; McLean Julie E; Saunders Stuart M; Stroud Robert E; Spinale Francis G
Protein kinase C isoform activation and endothelin-1 mediated defects in myocyte contractility after cardioplegic arrest and reperfusion.
Circulation 2006;114(1 Suppl):I308-13.
2006: Lindsey Merry L; Escobar G Patricia; Mukherjee Rupak; Goshorn Danielle K; Sheats Nina J; Bruce James A; Mains I Matthew; Hendrick Jennifer K; Hewett Kenneth W; Gourdie Robert G; Matrisian Lynn M; Spinale Francis G
Matrix metalloproteinase-7 affects connexin-43 levels, electrical conduction, and survival after myocardial infarction.
Circulation 2006;113(25):2919-28.
2006: Ahmed S Hinan; Clark Leslie L; Pennington Weems R; Webb Carson S; Bonnema D Dirk; Leonardi Amy H; McClure Catherine D; Spinale Francis G; Zile Michael R
Matrix metalloproteinases/tissue inhibitors of metalloproteinases: relationship between changes in proteolytic determinants of matrix composition and structural, functional, and clinical manifestations of hypertensive heart disease.
Circulation 2006;113(17):2089-96.
2006: Flack English C; Lindsey Merry L; Squires Christina E; Kaplan Brooke S; Stroud Robert E; Clark Leslie L; Escobar Patricia G; Yarbrough William M; Spinale Francis G
Alterations in cultured myocardial fibroblast function following the development of left ventricular failure.
Journal of molecular and cellular cardiology 2006;40(4):474-83.
2006: Clark Leslie L; Ikonomidis John S; Crawford Fred A; Crumbley Arthur; Kratz John M; Stroud Martha R; Woolson Robert F; Bruce James J; Nicholas Joyce S; Lackland Daniel T; Zile Michael R; Spinale Francis G
Preoperative statin treatment is associated with reduced postoperative mortality and morbidity in patients undergoing cardiac surgery: an 8-year retrospective cohort study.
The Journal of thoracic and cardiovascular surgery 2006;131(3):679-85.
2006: Apple Kimberly A; Yarbrough William M; Mukherjee Rupak; Deschamps Anne M; Escobar Patricia G; Mingoia Joseph T; Sample Jeffrey A; Hendrick Jennifer W; Dowdy Kathryn B; McLean Julie E; Stroud Robert E; O'Neill Timothy P; Spinale Francis G
Selective targeting of matrix metalloproteinase inhibition in post-infarction myocardial remodeling.
Journal of cardiovascular pharmacology 2006;47(2):228-35.
2006: Mukherjee Rupak; Herron Amanda R; Lowry Abigail S; Stroud Robert E; Stroud Martha R; Wharton J Marcus; Ikonomidis John S; Crumbley A Jackson; Spinale Francis G; Gold Michael R
Selective induction of matrix metalloproteinases and tissue inhibitor of metalloproteinases in atrial and ventricular myocardium in patients with atrial fibrillation.
The American journal of cardiology 2006;97(4):532-7.
2006: Newby Andrew C; Pauschinger Matthias; Spinale Francis G
From tadpole tails to transgenic mice: metalloproteinases have brought about a metamorphosis in our understanding of cardiovascular disease.
Cardiovascular research 2006;69(3):559-61.
2006: Deschamps Anne M; Spinale Francis G
Pathways of matrix metalloproteinase induction in heart failure: bioactive molecules and transcriptional regulation.
Cardiovascular research 2006;69(3):666-76.
2006: Lindsey Merry L; Escobar G Patricia; Dobrucki Lawrence W; Goshorn Danielle K; Bouges Shenikqua; Mingoia Joseph T; McClister David M; Su Haili; Gannon Joseph; MacGillivray Catherine; Lee Richard T; Sinusas Albert J; Spinale Francis G
Matrix metalloproteinase-9 gene deletion facilitates angiogenesis after myocardial infarction.
American journal of physiology. Heart and circulatory physiology 2006;290(1):H232-9.
2005: Su Haili; Spinale Francis G; Dobrucki Lawrence W; Song James; Hua Jing; Sweterlitsch Sarah; Dione Donald P; Cavaliere Patti; Chow Conroy; Bourke Brian N; Hu Xiao-Yu; Azure Michael; Yalamanchili Padmaja; Liu Richard; Cheesman Edward H; Robinson Simon; Edwards D Scott; Sinusas Albert J
Noninvasive targeted imaging of matrix metalloproteinase activation in a murine model of postinfarction remodeling.
Circulation 2005;112(20):3157-67.
2005: Ikonomidis John S; Barbour John R; Amani Zainab; Stroud Robert E; Herron Amanda R; McClister David M; Camens Sarah E; Lindsey Merry L; Mukherjee Rupak; Spinale Francis G
Effects of deletion of the matrix metalloproteinase 9 gene on development of murine thoracic aortic aneurysms.
Circulation 2005;112(9 Suppl):I242-8.
2005: Blom Aaron S; Mukherjee Rupak; Pilla James J; Lowry Abigail S; Yarbrough William M; Mingoia Joseph T; Hendrick Jennifer W; Stroud Robert E; McLean Julie E; Affuso John; Gorman Robert C; Gorman Joseph H; Acker Michael A; Spinale Francis G
Cardiac support device modifies left ventricular geometry and myocardial structure after myocardial infarction.
Circulation 2005;112(9):1274-83.
2005: Blom Aaron S; Pilla James J; Gorman Robert C; Gorman Joseph H; Mukherjee Rupak; Spinale Francis G; Acker Michael A
Infarct size reduction and attenuation of global left ventricular remodeling with the CorCap cardiac support device following acute myocardial infarction in sheep.
Heart failure reviews 2005;10(2):125-39.
2005: Deschamps Anne M; Spinale Francis G
Matrix modulation and heart failure: new concepts question old beliefs.
Current opinion in cardiology 2005;20(3):211-6.
2005: Deschamps Anne M; Apple Kimberly A; Leonardi Amy H; McLean Julie E; Yarbrough William M; Stroud Robert E; Clark Leslie L; Sample Jeffrey A; Spinale Francis G
Myocardial interstitial matrix metalloproteinase activity is altered by mechanical changes in LV load: interaction with the angiotensin type 1 receptor.
Circulation research 2005;96(10):1110-8.
2005: Lindsey Merry L; Goshorn Danielle K; Squires Christina E; Escobar G Patricia; Hendrick Jennifer W; Mingoia Joseph T; Sweterlitsch Sarah E; Spinale Francis G
Age-dependent changes in myocardial matrix metalloproteinase/tissue inhibitor of metalloproteinase profiles and fibroblast function.
Cardiovascular research 2005;66(2):410-9.
2005: Deschamps Anne M; Spinale Francis G
Disruptions and detours in the myocardial matrix highway and heart failure.
Current heart failure reports 2005;2(1):10-7.
2005: Multani M Marlina; Ikonomidis John S; Kim Peter Y; Miller Elizabeth A; Payne Kim J; Mukherjee Rupak; Dorman B Hugh; Spinale Francis G
Dynamic and differential changes in myocardial and plasma endothelin in patients undergoing cardiopulmonary bypass.
The Journal of thoracic and cardiovascular surgery 2005;129(3):584-90.
2005: Stroud Robert E; Deschamps Anne M; Lowry Abigail S; Hardin Amy E; Mukherjee Rupak; Lindsey Merry L; Ramamoorthy Sammanda; Zile Michael R; Spencer William H; Spinale Francis G
Plasma monitoring of the myocardial specific tissue inhibitor of metalloproteinase-4 after alcohol septal ablation in hypertrophic obstructive cardiomyopathy.
Journal of cardiac failure 2005;11(2):124-30.
2005: Deschamps Anne M; Yarbrough William M; Squires Christina E; Allen Rebecca A; McClister David M; Dowdy Kathryn B; McLean Julie E; Mingoia Joseph T; Sample Jeffrey A; Mukherjee Rupak; Spinale Francis G
Trafficking of the membrane type-1 matrix metalloproteinase in ischemia and reperfusion: relation to interstitial membrane type-1 matrix metalloproteinase activity.
Circulation 2005;111(9):1166-74.
2005: Ikonomidis John S; Hendrick Jennifer W; Parkhurst Andrea M; Herron Amanda R; Escobar Patricia G; Dowdy Kathryn B; Stroud Robert E; Hapke Elizabeth; Zile Michael R; Spinale Francis G
Accelerated LV remodeling after myocardial infarction in TIMP-1-deficient mice: effects of exogenous MMP inhibition.
American journal of physiology. Heart and circulatory physiology 2005;288(1):H149-58.
2004: Yarbrough William M; Mukherjee Rupak; Squires Christina E; Reese Emily S; Leiser Jennifer S; Stroud Robert E; Sample Jeffrey A; Hendrick Jennifer W; Mingoia Joseph T; McLean Julie E; Hardin Amy E; Dowdy Kathryn B; Spinale Francis G
Caspase inhibition attenuates contractile dysfunction following cardioplegic arrest and rewarming in the setting of left ventricular failure.
Journal of cardiovascular pharmacology 2004;44(6):645-50.
2004: Buckberg Gerald D; Weisfeldt Myron L; Ballester Manel; Beyar Raphael; Burkhoff Daniel; Coghlan H Cecil; Doyle Mark; Epstein Neal D; Gharib Morteza; Ideker Ray E; Ingels Neil B; LeWinter Martin M; McCulloch Andrew D; Pohost Gerald M; Reinlib Leslie J; Sahn David J; Sopko George; Spinale Francis G; Spotnitz Henry M; Torrent-Guasp Francisco; Shapiro Edward P
Left ventricular form and function: scientific priorities and strategic planning for development of new views of disease.
Circulation 2004;110(14):e333-6.
2004: Wilson Eric M; Diwan Abhinav; Spinale Francis G; Mann Douglas L
Duality of innate stress responses in cardiac injury, repair, and remodeling.
Journal of molecular and cellular cardiology 2004;37(4):801-11.
2004: Ikonomidis John S; Gibson William C; Butler Jessica E; McClister David M; Sweterlitsch Sarah E; Thompson Robert P; Mukherjee Rupak; Spinale Francis G
Effects of deletion of the tissue inhibitor of matrix metalloproteinases-1 gene on the progression of murine thoracic aortic aneurysms.
Circulation 2004;110(11 Suppl 1):II268-73.
2004: Spinale Francis G
Cell-matrix signaling and thrombospondin: another link to myocardial matrix remodeling.
Circulation research 2004;95(5):446-8.
2004: Garner Jessica R; Stroud Robert E; Finklea Laura; Ikonomidis John S; Dorman B Hugh; Spinale Francis G
The effects of leukocyte reduction on matrix metalloproteinase release in cardiopulmonary bypass.
The Journal of extra-corporeal technology 2004;36(2):185-90.
2004: Mukherjee Rupak; Yarbrough William M; Reese Emily S; Leiser Jennifer S; Sample Jeffrey A; Mingoia Joseph T; Hardin Amy E; Stroud Robert E; McLean Julie E; Hendrick Jennifer W; Spinale Francis G
Myocyte contractility with caspase inhibition and simulated hyperkalemic cardioplegic arrest.
The Annals of thoracic surgery 2004;77(5):1684-9; discussion 1689-90.
2004: Spinale Francis G
Matrix metalloproteinase gene polymorphisms in heart failure: new pieces to the myocardial matrix puzzle.
European heart journal 2004;25(8):631-3.
2004: Mukherjee Rupak; Parkhurst Andrea M; Mingoia Joseph T; Sweterlitsch Sarah E; Leiser Jennifer S; Escobar G Patricia; Spinale Francis G; Saul J Philip
Myocardial remodeling after discrete radiofrequency injury: effects of tissue inhibitor of matrix metalloproteinase-1 gene deletion.
American journal of physiology. Heart and circulatory physiology 2004;286(4):H1242-7.
2004: Dorman B Hugh; Kratz John M; Multani Marlina M; Baron Ruth; Farrar Emily; Walton Scott; Payne Kim; Ikonomiois John; Reeves Scott; Mukherjee Rupak; Spinale Francis G
A prospective, randomized study of endothelin and postoperative recovery in off-pump versus conventional coronary artery bypass surgery.
Journal of cardiothoracic and vascular anesthesia 2004;18(1):25-9.
2004: Diwan Abhinav; Dibbs Ziad; Nemoto Shintaro; DeFreitas Gilberto; Carabello Blase A; Sivasubramanian Natarajan; Wilson Eric M; Spinale Francis G; Mann Douglas L
Targeted overexpression of noncleavable and secreted forms of tumor necrosis factor provokes disparate cardiac phenotypes.
Circulation 2004;109(2):262-8.
2004: Chapman R English; Spinale Francis G
Extracellular protease activation and unraveling of the myocardial interstitium: critical steps toward clinical applications.
American journal of physiology. Heart and circulatory physiology 2004;286(1):H1-H10.
2003: Yarbrough William M; Mukherjee Rupak; Escobar G Patricia; Sample Jeffrey A; McLean Julie E; Dowdy Kathryn B; Hendrick Jennifer W; Gibson William C; Hardin Amy E; Mingoia Joseph T; White Patrick C; Stiko Ann; Armstrong Robert C; Crawford Fred A; Spinale Francis G
Pharmacologic inhibition of intracellular caspases after myocardial infarction attenuates left ventricular remodeling: a potentially novel pathway.
The Journal of thoracic and cardiovascular surgery 2003;126(6):1892-9.
2003: Yarbrough William M; Mukherjee Rupak; Escobar G Patricia; Hendrick Jennifer W; Sample Jeffrey A; Dowdy Kathryn B; McLean Julie E; Mingoia Joseph T; Crawford Fred A; Spinale Francis G
Modulation of calcium transport improves myocardial contractility and enzyme profiles after prolonged ischemia-reperfusion.
The Annals of thoracic surgery 2003;76(6):2054-61; discussion 2061.
2003: Yarbrough William M; Mukherjee Rupak; Escobar G Patricia; Mingoia Joseph T; Sample Jeffrey A; Hendrick Jennifer W; Dowdy Kathryn B; McLean Julie E; Stroud Robert E; Spinale Francis G
Direct inhibition of the sodium/hydrogen exchanger after prolonged regional ischemia improves contractility on reperfusion independent of myocardial viability.
The Journal of thoracic and cardiovascular surgery 2003;126(5):1489-97.
2003: Ikonomidis John S; Gibson William C; Gardner Jonathan; Sweterlitsch Sarah; Thompson Robert P; Mukherjee Rupak; Spinale Francis G
A murine model of thoracic aortic aneurysms.
The Journal of surgical research 2003;115(1):157-63.
2003: Yarbrough William M; Mukherjee Rupak; Escobar G Patricia; Mingoia Joseph T; Sample Jeffrey A; Hendrick Jennifer W; Dowdy Kathryn B; McLean Julie E; Lowry Abigail S; O'Neill Timothy P; Spinale Francis G
Selective targeting and timing of matrix metalloproteinase inhibition in post-myocardial infarction remodeling.
Circulation 2003;108(14):1753-9.
2003: Dibbs Ziad I; Diwan Abhinav; Nemoto Shintaro; DeFreitas Gilberto; Abdellatif Maha; Carabello Blase A; Spinale Francis G; Feuerstein Giora; Sivasubramanian Natarajan; Mann Douglas L
Targeted overexpression of transmembrane tumor necrosis factor provokes a concentric cardiac hypertrophic phenotype.
Circulation 2003;108(8):1002-8.
2003: Flesch Markus; Höper Anje; Dell'Italia Louis; Evans Kenda; Bond Richard; Peshock Ronald; Diwan Abhinav; Brinsa Theresa A; Wei Chih-Chang; Sivasubramanian Natarajan; Spinale Francis G; Mann Douglas L
Activation and functional significance of the renin-angiotensin system in mice with cardiac restricted overexpression of tumor necrosis factor.
Circulation 2003;108(5):598-604.
2003: Schneider Susan; Gunasinghe Himali; Sistino Joseph; Blackwell Mindy; Spinale Francis
Effects of leukocyte depletion filters on matrix metalloproteinase activation in an extracorporeal circulation circuit.
The Journal of extra-corporeal technology 2003;35(2):139-42.
2003: Wilson Eric M; Moainie Sina L; Baskin Julia M; Lowry Abigail S; Deschamps Anne M; Mukherjee Rupak; Guy T Sloane; St John-Sutton Martin G; Gorman Joseph H; Edmunds L Henry; Gorman Robert C; Spinale Francis G
Region- and type-specific induction of matrix metalloproteinases in post-myocardial infarction remodeling.
Circulation 2003;107(22):2857-63.
2003: Chapman R English; Scott Amelia A; Deschamps Anne M; Lowry Abigail S; Stroud Robert E; Ikonomidis John S; Spinale Francis G
Matrix metalloproteinase abundance in human myocardial fibroblasts: effects of sustained pharmacologic matrix metalloproteinase inhibition.
Journal of molecular and cellular cardiology 2003;35(5):539-48.
2003: Yarbrough William M; Mukherjee Rupak; Brinsa Theresa A; Dowdy Kathryn B; Scott Amelia A; Escobar G Patricia; Joffs Cassandra; Lucas David G; Crawford Fred A; Spinale Francis G
Matrix metalloproteinase inhibition modifies left ventricular remodeling after myocardial infarction in pigs.
The Journal of thoracic and cardiovascular surgery 2003;125(3):602-10.
2003: King Mary K; Coker Mytsi L; Goldberg Aaron; McElmurray James H; Gunasinghe Himali R; Mukherjee Rupak; Zile Michael R; O'Neill Timothy P; Spinale Francis G
Selective matrix metalloproteinase inhibition with developing heart failure: effects on left ventricular function and structure.
Circulation research 2003;92(2):177-85.
2003: Mukherjee Rupak; Brinsa Theresa A; Dowdy Kathryn B; Scott Amelia A; Baskin Julia M; Deschamps Anne M; Lowry Abigail S; Escobar G Patricia; Lucas David G; Yarbrough William M; Zile Michael R; Spinale Francis G
Myocardial infarct expansion and matrix metalloproteinase inhibition.
Circulation 2003;107(4):618-25.
2003: Yarbrough William M; Spinale Francis G
Large animal models of congestive heart failure: a critical step in translating basic observations into clinical applications.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology 2003;10(1):77-86.
2003: Baicu Catalin F; Stroud Jason D; Livesay Virginia A; Hapke Elizabeth; Holder Jennifer; Spinale Francis G; Zile Michael R
Changes in extracellular collagen matrix alter myocardial systolic performance.
American journal of physiology. Heart and circulatory physiology 2003;284(1):H122-32.
2003: Creemers Esther E J M; Davis Jeniffer N; Parkhurst Andrea M; Leenders Peter; Dowdy Kathryn B; Hapke Elizabeth; Hauet Anne M; Escobar Patricia G; Cleutjens Jack P M; Smits Jos F M; Daemen Mat J A P; Zile Michael R; Spinale Francis G
Deficiency of TIMP-1 exacerbates LV remodeling after myocardial infarction in mice.
American journal of physiology. Heart and circulatory physiology 2003;284(1):H364-71.
2003: Lindsey Merry L; Mann Douglas L; Entman Mark L; Spinale Francis G
Extracellular matrix remodeling following myocardial injury.
Annals of medicine 2003;35(5):316-26.
2002: Spinale Francis G
The extracellular matrix: summation.
Journal of cardiac failure 2002;8(6 Suppl):S349-50.
2002: Spinale Francis G; Gunasinghe Himali; Sprunger Philip D; Baskin Julia M; Bradham William C
Extracellular degradative pathways in myocardial remodeling and progression to heart failure.
Journal of cardiac failure 2002;8(6 Suppl):S332-8.
2002: Wilson Eric M; Gunasinghe Himali R; Coker Mytsi L; Sprunger Philip; Lee-Jackson Dorellyn; Bozkurt Biykem; Deswal Anita; Mann Douglas L; Spinale Francis G
Plasma matrix metalloproteinase and inhibitor profiles in patients with heart failure.
Journal of cardiac failure 2002;8(6):390-8.
2002: Bradham William S; Gunasinghe Himali; Holder Jennifer R; Multani Marlina; Killip Donna; Anderson Marianne; Meyer Denise; Spencer William H; Torre-Amione Guillermo; Spinale Francis G
Release of matrix metalloproteinases following alcohol septal ablation in hypertrophic obstructive cardiomyopathy.
Journal of the American College of Cardiology 2002;40(12):2165-73.
2002: Spinale Francis G
Bioactive peptide signaling within the myocardial interstitium and the matrix metalloproteinases.
Circulation research 2002;91(12):1082-4.
2002: Mukherjee Rupak; Multani M Marlina; Sample Jeffrey A; Dowdy Kathryn B; Zellner James L; Hoover Donald B; Spinale Francis G
Effects of adrenomedullin on human myocyte contractile function and beta-adrenergic response.
Journal of cardiovascular pharmacology and therapeutics 2002;7(4):235-40.
2002: Spinale Francis G
The bioactive peptide endothelin causes multiple biologic responses relevant to myocardial and vascular performance after cardiac surgery.
The Journal of thoracic and cardiovascular surgery 2002;123(6):1031-4.
2002: Stroud Jason D; Baicu Catalin F; Barnes Mary A; Spinale Francis G; Zile Michael R
Viscoelastic properties of pressure overload hypertrophied myocardium: effect of serine protease treatment.
American journal of physiology. Heart and circulatory physiology 2002;282(6):H2324-35.
2002: Lucas David G; Hendrick Jennifer W; Sample Jeffrey A; Mukherjee Rupak; Escobar Gladys P; Smits Glenn J; Crawford Fred A; Spinale Francis G
Cardiorenal effects of adenosine subtype 1 (A1) receptor inhibition in an experimental model of heart failure.
Journal of the American College of Surgeons 2002;194(5):603-9.
2002: Perry Gilbert J; Wei Chih-Chang; Hankes Gerald H; Dillon S Ray; Rynders Patricia; Mukherjee Rupak; Spinale Francis G; Dell'Italia Louis J
Angiotensin II receptor blockade does not improve left ventricular function and remodeling in subacute mitral regurgitation in the dog.
Journal of the American College of Cardiology 2002;39(8):1374-9.
2002: Bradham William S; Moe Gordon; Wendt Katherine A; Scott Amelia A; Konig Andrea; Romanova Marina; Naik George; Spinale Francis G
TNF-alpha and myocardial matrix metalloproteinases in heart failure: relationship to LV remodeling.
American journal of physiology. Heart and circulatory physiology 2002;282(4):H1288-95.
2002: Bradham William S; Bozkurt Biykem; Gunasinghe Himali; Mann Douglas; Spinale Francis G
Tumor necrosis factor-alpha and myocardial remodeling in progression of heart failure: a current perspective.
Cardiovascular research 2002;53(4):822-30.
2002: Spinale Francis G
Matrix metalloproteinases: regulation and dysregulation in the failing heart.
Circulation research 2002;90(5):520-30.
2002: Schultz David; Su Xuefeng; Wei Chih-Chang; Bishop Sanford P; Powell Pamela; Hankes Gerald H; Dillon A Ray; Rynders Patricia; Spinale Francis G; Walcott Gregory; Ideker Raymond; Dell'Italia Louis J
Downregulation of ANG II receptor is associated with compensated pressure-overload hypertrophy in the young dog.
American journal of physiology. Heart and circulatory physiology 2002;282(2):H749-56.
2001: Gunasinghe S K; Ikonomidis J; Spinale F G
Contributory role of matrix metalloproteinases in cardiovascular remodeling.
Current drug targets. Cardiovascular & haematological disorders 2001;1(2):75-91.
2001: Wilson E M; Spinale F G
Myocardial remodelling and matrix metalloproteinases in heart failure: turmoil within the interstitium.
Annals of medicine 2001;33(9):623-34.
2001: Multani M M; Krombach R S; Hendrick J W; Baicu S C; Joffs C; Sample J A; deGasparo M; Spinale F G
Long-term angiotensin-converting enzyme and angiotensin I--receptor inhibition in pacing-induced heart failure: effects on myocardial interstitial bradykinin levels.
Journal of cardiac failure 2001;7(4):348-54.
2001: Ergul A; Joffs C; Walker A C; Spinale F G
Potential role of endothelin receptor antagonists in the setting of cardiopulmonary bypass: relevance to myocardial performance.
Heart failure reviews 2001;6(4):287-94.
2001: Multani M M; Krombach R S; Goldberg A T; King M K; Hendrick J W; Sample J A; Baicu S C; Joffs C; deGasparo M; Spinale F G
Myocardial bradykinin following acute angiotensin-converting enzyme inhibition, AT1 receptor blockade, or combined inhibition in congestive heart failure.
Journal of cardiovascular pharmacology and therapeutics 2001;6(4):369-76.
2001: Lucas D G; Patterson T; Hendrick J W; Holder J; Sample J A; Joffs C; Davis J; Goldberg A; Mukherjee R; Smits G J; Spinale F G
Effects of adenosine receptor subtype A1 on ventricular and renal function.
Journal of cardiovascular pharmacology 2001;38(4):618-24.
2001: Etoh T; Joffs C; Deschamps A M; Davis J; Dowdy K; Hendrick J; Baicu S; Mukherjee R; Manhaini M; Spinale F G
Myocardial and interstitial matrix metalloproteinase activity after acute myocardial infarction in pigs.
American journal of physiology. Heart and circulatory physiology 2001;281(3):H987-94.
2001: Sivasubramanian N; Coker M L; Kurrelmeyer K M; MacLellan W R; DeMayo F J; Spinale F G; Mann D L
Left ventricular remodeling in transgenic mice with cardiac restricted overexpression of tumor necrosis factor.
Circulation 2001;104(7):826-31.
2001: Joffs C; Walker C A; Hendrick J W; Fary D J; Almany D K; Davis J N; Goldberg A T; Crawford F A; Spinale F G
Endothelin receptor subtype A blockade selectively reduces pulmonary pressure after cardiopulmonary bypass.
The Journal of thoracic and cardiovascular surgery 2001;122(2):365-70.
2001: Bond B R; Dorman B H; Clair M J; Walker C A; Pinosky M L; Reeves S T; Walton S; Kratz J M; Zellner J L; Crumbley A J; Multani M M; Spinale F G
Endothelin-1 during and after cardiopulmonary bypass: association to graft sensitivity and postoperative recovery.
The Journal of thoracic and cardiovascular surgery 2001;122(2):358-64.
2001: Coker M L; Jolly J R; Joffs C; Etoh T; Holder J R; Bond B R; Spinale F G
Matrix metalloproteinase expression and activity in isolated myocytes after neurohormonal stimulation.
American journal of physiology. Heart and circulatory physiology 2001;281(2):H543-51.
2001: McElmurray J H; Mukherjee R; Patterson T M; Goldberg A; King M K; Hendrick J W; Gay D M; Clair M J; Jolly J R; Spinale F G
Comparison of amlodipine or nifedipine treatment with developing congestive heart failure: effects on myocyte contractility.
Journal of cardiac failure 2001;7(2):158-64.
2001: Walker C A; Ergul A; Grubbs A; Zile M R; Zellner J L; Crumbley A J; Spinale F G
beta-Adrenergic and endothelin receptor interaction in dilated human cardiomyopathic myocardium.
Journal of cardiac failure 2001;7(2):129-37.
2001: Joffs C; Gunasinghe H R; Multani M M; Dorman B H; Kratz J M; Crumbley A J; Crawford F A; Spinale F G
Cardiopulmonary bypass induces the synthesis and release of matrix metalloproteinases.
The Annals of thoracic surgery 2001;71(5):1518-23.
2001: Peterson J T; Hallak H; Johnson L; Li H; O'Brien P M; Sliskovic D R; Bocan T M; Coker M L; Etoh T; Spinale F G
Matrix metalloproteinase inhibition attenuates left ventricular remodeling and dysfunction in a rat model of progressive heart failure.
Circulation 2001;103(18):2303-9.
2001: Ergul A; Grubbs A L; Zhang Y; Joffs C; Sample J A; King M K; Spinale F G
Expression and activity of pulmonary endothelin converting enzyme in heart failure: relation to endothelin biosynthesis and receptor distribution.
Journal of cardiac failure 2001;7(1):84-91.
2001: King M K; Gay D M; Pan L C; McElmurray J H; Hendrick J W; Pirie C; Morrison A; Ding C; Mukherjee R; Spinale F G
Treatment with a growth hormone secretagogue in a model of developing heart failure: effects on ventricular and myocyte function.
Circulation 2001;103(2):308-13.
2000: Ergul A; Grubbs A L; Zhang Y; Spinale F G
Selective upregulation of endothelin converting enzyme-1a in the human failing heart.
Journal of cardiac failure 2000;6(4):314-20.
2000: Walker C A; Baicu S C; Goldberg A T; Widener C E; Fary D J; Almany D K; Ergul A; Crawford F A; Spinale F G
Temporal endothelin dynamics of the myocardial interstitium and systemic circulation in cardiopulmonary bypass.
The Journal of thoracic and cardiovascular surgery 2000;120(5):864-71.
2000: Krombach R S; McElmuray J H; Gay D M; Clair M J; Mukherjee R; Goldberg A T; Baicu S C; Spinale F G
Bradykinin degradation and relation to myocyte contractility.
Journal of cardiovascular pharmacology and therapeutics 2000;5(4):291-9.
2000: Dorman B H; Bond B R; Clair M J; Walker C A; Pinosky M L; Reeves S T; Kratz J M; Zellner J L; Crumbley A J; Multani M M; Spinale F G
Temporal synthesis and release of endothelin within the systemic and myocardial circulation during and after cardiopulmonary bypass: relation to postoperative recovery.
Journal of cardiothoracic and vascular anesthesia 2000;14(5):540-5.
2000: Spinale F G; Coker M L; Heung L J; Bond B R; Gunasinghe H R; Etoh T; Goldberg A T; Zellner J L; Crumbley A J
A matrix metalloproteinase induction/activation system exists in the human left ventricular myocardium and is upregulated in heart failure.
Circulation 2000;102(16):1944-9.
2000: Spinale F G
The effects of growth hormone supplementation on left ventricular function with the development of congestive heart failure.
Italian heart journal : official journal of the Italian Federation of Cardiology 2000;1 Suppl 3():S34-6.
2000: New R B; Sampson A C; King M K; Hendrick J W; Clair M J; McElmurray J H; Mandel J; Mukherjee R; de Gasparo M; Spinale F G
Effects of combined angiotensin II and endothelin receptor blockade with developing heart failure: effects on left ventricular performance.
Circulation 2000;102(12):1447-53.
2000: Clair M J; King M K; Goldberg A T; Hendrick J W; Nisato R; Gay D M; Morrison A E; McElmurray J H; Krombach R S; Bond B R; Cazaubon C; Nisato D; Spinale F G
Selective vasopressin, angiotensin II, or dual receptor blockade with developing congestive heart failure.
The Journal of pharmacology and experimental therapeutics 2000;293(3):852-60.
2000: Ergul A; Walker C A; Goldberg A; Baicu S C; Hendrick J W; King M K; Spinale F G
ET-1 in the myocardial interstitium: relation to myocyte ECE activity and expression.
American journal of physiology. Heart and circulatory physiology 2000;278(6):H2050-6.
2000: Dorman B H; New R B; Bond B R; Mukherjee R; Mukhin Y V; McElmurray J H; Spinale F G
Myocyte endothelin exposure during cardioplegic arrest exacerbates contractile dysfunction after reperfusion.
Anesthesia and analgesia 2000;90(5):1080-5.
2000: Spinale F G; Coker M L; Bond B R; Zellner J L
Myocardial matrix degradation and metalloproteinase activation in the failing heart: a potential therapeutic target.
Cardiovascular research 2000;46(2):225-38.
2000: Bond B R; Zellner J L; Dorman B H; Multani M M; Kratz J M; Crumbley A J; Crawford F A; Spinale F G
Differential effects of calcium channel antagonists in the amelioration of radial artery vasospasm.
The Annals of thoracic surgery 2000;69(4):1035-40; discussion 1040-1.
2000: Goldberg A T; Bond B R; Mukherjee R; New R B; Zellner J L; Crawford F A; Spinale F G
Endothelin receptor pathway in human left ventricular myocytes: relation to contractility.
The Annals of thoracic surgery 2000;69(3):711-5; discussion 716.
2000: Dorman B H; Sade R M; Burnette J S; Wiles H B; Pinosky M L; Reeves S T; Bond B R; Spinale F G
Magnesium supplementation in the prevention of arrhythmias in pediatric patients undergoing surgery for congenital heart defects.
American heart journal 2000;139(3):522-8.
2000: Nagatsu M; Spinale F G; Koide M; Tagawa H; DeFreitas G; Cooper G; Carabello B A
Bradycardia and the role of beta-blockade in the amelioration of left ventricular dysfunction.
Circulation 2000;101(6):653-9.
2000: Walker C A; Crawford F A; Spinale F G
Myocyte contractile dysfunction with hypertrophy and failure: relevance to cardiac surgery.
The Journal of thoracic and cardiovascular surgery 2000;119(2):388-400.
2000: Caparas S N; Clair M J; Krombach R S; Hendrick J W; Houck W V; Kribbs S B; Mukherjee R; Tempel G E; Spinale F G
Brain blood flow patterns after the development of congestive heart failure: effects of treadmill exercise.
Critical care medicine 2000;28(1):209-14.
2000: Roten L; Nemoto S; Simsic J; Coker M L; Rao V; Baicu S; Defreyte G; Soloway P J; Zile M R; Spinale F G
Effects of gene deletion of the tissue inhibitor of the matrix metalloproteinase-type 1 (TIMP-1) on left ventricular geometry and function in mice.
Journal of molecular and cellular cardiology 2000;32(1):109-20.
2000: Nagatomo Y; Carabello B A; Coker M L; McDermott P J; Nemoto S; Hamawaki M; Spinale F G
Differential effects of pressure or volume overload on myocardial MMP levels and inhibitory control.
American journal of physiology. Heart and circulatory physiology 2000;278(1):H151-61.
2000: Spinale F G; Lucas D G
Surgical options for the treatment of heart failure.
Clinical cornerstone 2000;3(2):45-56.
1999: Balaji S; Hewett K W; Krombach R S; Clair M J; Ye X; Spinale F G
Inducible lethal ventricular arrhythmias in swine with pacing-induced heart failure.
Basic research in cardiology 1999;94(6):496-503.
1999: Spinale F G
Cellular and molecular therapeutic targets for treatment of contractile dysfunction after cardioplegic arrest.
The Annals of thoracic surgery 1999;68(5):1934-41.
1999: Houck W V; Pan L C; Kribbs S B; Clair M J; McDaniel G M; Krombach R S; Merritt W M; Pirie C; Iannini J P; Mukherjee R; Spinale F G
Effects of growth hormone supplementation on left ventricular morphology and myocyte function with the development of congestive heart failure.
Circulation 1999;100(19):2003-9.
1999: Loging J A; New R B; Baicu S C; King M K; Hendrick J W; Crawford F A; de Gasparo M; Spinale F G
Effects of angiotensin type-I receptor blockade on pericardial fibrosis.
The Journal of surgical research 1999;87(1):101-7.
1999: McElmurray J H; Mukherjee R; New R B; Sampson A C; King M K; Hendrick J W; Goldberg A; Peterson T J; Hallak H; Zile M R; Spinale F G
Angiotensin-converting enzyme and matrix metalloproteinase inhibition with developing heart failure: comparative effects on left ventricular function and geometry.
The Journal of pharmacology and experimental therapeutics 1999;291(2):799-811.
1999: Krombach R S; Clair M J; Hendrick J W; Mukherjee R; Houck W V; Hebbar L; Kribbs S B; Dodd M G; Spinale F G
Amlodipine therapy in congestive heart failure: hemodynamic and neurohormonal effects at rest and after treadmill exercise.
The American journal of cardiology 1999;84(4A):3L-15L.
1999: Spinale F G; Coker M L; Krombach S R; Mukherjee R; Hallak H; Houck W V; Clair M J; Kribbs S B; Johnson L L; Peterson J T; Zile M R
Matrix metalloproteinase inhibition during the development of congestive heart failure : effects on left ventricular dimensions and function.
Circulation research 1999;85(4):364-76.
1999: Coker M L; Doscher M A; Thomas C V; Galis Z S; Spinale F G
Matrix metalloproteinase synthesis and expression in isolated LV myocyte preparations.
The American journal of physiology 1999;277(2 Pt 2):H777-87.
1999: Walker C A; Spinale F G
The structure and function of the cardiac myocyte: a review of fundamental concepts.
The Journal of thoracic and cardiovascular surgery 1999;118(2):375-82.
1999: Coker M L; Zellner J L; Crumbley A J; Spinale F G
Defects in matrix metalloproteinase inhibitory stoichiometry and selective MMP induction in patients with nonischemic or ischemic dilated cardiomyopathy.
Annals of the New York Academy of Sciences 1999;878():559-62.
1999: Rao V U; Spinale F G
Controlling myocardial matrix remodeling: implications for heart failure.
Cardiology in review 1999;7(3):136-43.
1999: Spinale F G
Novel approaches to retard ventricular remodeling in heart failure.
European journal of heart failure : journal of the Working Group on Heart Failure of the European Society of Cardiology 1999;1(1):17-23.
1998: Spinale F G; Iannini J P; Mukherjee R; Melton D M; de Gasparo M
Angiotensin AT1 receptor inhibition, angiotensin-converting enzyme inhibition, and combination therapy with developing heart failure: cellular mechanisms of action.
Journal of cardiac failure 1998;4(4):325-32.
1998: Clair M J; Krombach R S; Hendrick J W; Houck W V; Hebbar L; Kribbs S B; Rios G; Whitebread S; Mukherjee R; de Gasparo M; Spinale F G
AT1 angiotensin II receptor inhibition in pacing-induced heart failure: effects on left ventricular performance and regional blood flow patterns.
Journal of cardiac failure 1998;4(4):311-23.
1998: Thomas C V; McDaniel G M; Holzgrefe H H; Mukherjee R; Hird R B; Walker J D; Hebbar L; Powell J R; Spinale F G
Chronic dual inhibition of angiotensin-converting enzyme and neutral endopeptidase during the development of left ventricular dysfunction in dogs.
Journal of cardiovascular pharmacology 1998;32(6):902-12.
1998: Clair M J; Krombach R S; Coker M L; Heslin T L; Kribbs S B; de Gasparo M; Spinale F G
Angiotensin AT1 receptor inhibition in pacing induced heart failure: effects on left ventricular myocardial collagen content and composition.
Journal of molecular and cellular cardiology 1998;30(11):2355-64.
1998: Dorman B H; Hebbar L; Zellner J L; New R B; Houck W V; Acsell J; Nettles C; Hendrick J W; Sampson A P; Mukherjee R; Spinale F G
ATP-sensitive potassium channel activation before cardioplegia. Effects on ventricular and myocyte function.
Circulation 1998;98(19 Suppl):II176-83.
1998: Saad D; Mukherjee R; Thomas P B; Iannini J P; Basler C G; Hebbar L; O S J; Moreland S; Webb M L; Powell J R; Spinale F G
The effects of endothelin-A receptor blockade during the progression of pacing-induced congestive heart failure.
Journal of the American College of Cardiology 1998;32(6):1779-86.
1998: Mukherjee R; Spinale F G
L-type calcium channel abundance and function with cardiac hypertrophy and failure: a review.
Journal of molecular and cellular cardiology 1998;30(10):1899-916.
1998: Mann D L; Spinale F G
Activation of matrix metalloproteinases in the failing human heart: breaking the tie that binds.
Circulation 1998;98(17):1699-702.
1998: Spinale F G; Mukherjee R; Krombach R S; Clair M J; Hendrick J W; Houck W V; Hebbar L; Kribbs S B; Zellner J L; Dodd M G
Chronic amlodipine treatment during the development of heart failure.
Circulation 1998;98(16):1666-74.
1998: New R B; Zellner J L; Hebbar L; Mukherjee R; Sampson A C; Hendrick J W; Handy J R; Crawford F A; Spinale F G
Isolated left ventricular myocyte contractility in patients undergoing cardiac operations.
The Journal of thoracic and cardiovascular surgery 1998;116(3):495-502.
1998: Zellner J L; Kribbs S B; Dorman B H; Spinale F G
Cardiopulmonary bypass in a gravid patient: perioperative changes in endothelin levels.
The Annals of thoracic surgery 1998;66(1):268-70.
1998: Krombach R S; Clair M J; Hendrick J W; Houck W V; Zellner J L; Kribbs S B; Whitebread S; Mukherjee R; de Gasparo M; Spinale F G
Angiotensin converting enzyme inhibition, AT1 receptor inhibition, and combination therapy with pacing induced heart failure: effects on left ventricular performance and regional blood flow patterns.
Cardiovascular research 1998;38(3):631-45.
1998: Coker M L; Thomas C V; Clair M J; Hendrick J W; Krombach R S; Galis Z S; Spinale F G
Myocardial matrix metalloproteinase activity and abundance with congestive heart failure.
The American journal of physiology 1998;274(5 Pt 2):H1516-23.
1998: Houck W V; Kribbs S B; Zellner J L; Doscher M A; Joshi J D; Crawford F A; Spinale F G
Normothermic versus hypothermic hyperkalemic cardioplegia: effects on myocyte contractility.
The Annals of thoracic surgery 1998;65(5):1279-83.
1998: Thomas C V; Coker M L; Zellner J L; Handy J R; Crumbley A J; Spinale F G
Increased matrix metalloproteinase activity and selective upregulation in LV myocardium from patients with end-stage dilated cardiomyopathy.
Circulation 1998;97(17):1708-15.
1998: Bozkurt B; Kribbs S B; Clubb F J; Michael L H; Didenko V V; Hornsby P J; Seta Y; Oral H; Spinale F G; Mann D L
Pathophysiologically relevant concentrations of tumor necrosis factor-alpha promote progressive left ventricular dysfunction and remodeling in rats.
Circulation 1998;97(14):1382-91.
1998: Hebbar L; Houck W V; Zellner J L; Dorman B H; Spinale F G
Temporal relation of ATP-sensitive potassium-channel activation and contractility before cardioplegia.
The Annals of thoracic surgery 1998;65(4):1077-82.
1998: Spinale F G; Coker M L; Thomas C V; Walker J D; Mukherjee R; Hebbar L
Time-dependent changes in matrix metalloproteinase activity and expression during the progression of congestive heart failure: relation to ventricular and myocyte function.
Circulation research 1998;82(4):482-95.
1998: Kribbs S B; Merritt W M; Clair M J; Krombach R S; Houck W V; Dodd M G; Mukherjee R; Spinale F G
Amlodipine monotherapy, angiotensin-converting enzyme inhibition, and combination therapy with pacing-induced heart failure.
Hypertension 1998;31(3):755-65.
1998: Mukherjee R; Hewett K W; Walker J D; Basler C G; Spinale F G
Changes in L-type calcium channel abundance and function during the transition to pacing-induced congestive heart failure.
Cardiovascular research 1998;37(2):432-44.
1998: Eble D M; Walker J D; Samarel A M; Spinale F G
Myosin heavy chain synthesis during the progression of chronic tachycardia induced heart failure in rabbits.
Basic research in cardiology 1998;93(1):50-5.
1998: Houck W V; Thomas C V; Doscher M A; Wang Y H; Hebbar L; Joshi J D; Mukherjee R; Crawford F A; Spinale F G
Downstream defects in beta-adrenergic signaling and relation to myocyte contractility after cardioplegic arrest.
The Journal of thoracic and cardiovascular surgery 1998;115(1):190-9.
1997: Kribbs S B; Clair M J; Krombach R S; Hendrick J W; Thomas P B; Keever A T; Houch W V; Mukherjee R; Spinale F G
Pulmonary hemodynamics and endothelin levels in pacing-induced heart failure: during rest and exercise.
Journal of cardiac failure 1997;3(4):263-70.
1997: Hedgepath K R; Mukherjee R; Wang Z; Spinale F G
The relation between changes in myocyte orientation and contractile function with electrical field stimulation.
Basic research in cardiology 1997;92(6):385-90.
1997: Spinale F G; Holzgrefe H H; Mukherjee R; Webb M L; Hird R B; Cavallo M J; Powell J R; Koster W H
Angiotensin-converting enzyme inhibition and angiotensin II subtype-1 receptor blockade during the progression of left ventricular dysfunction: differential effects on myocyte contractile processes.
The Journal of pharmacology and experimental therapeutics 1997;283(3):1082-94.
1997: Spinale F G; Holzgrefe H H; Walker J D; Mukherjee R; Kribbs S B; Powell J R; Antonaccio M
Angiotensin II subtype-1 receptor blockade during the development of left ventricular hypertrophy in dogs: effects on ventricular and myocyte function.
Journal of cardiovascular pharmacology 1997;30(5):623-31.
1997: Dorman B H; Hebbar L; Clair M J; Hinton R B; Roy R C; Spinale F G
Potassium channel opener-augmented cardioplegia: protection of myocyte contractility with chronic left ventricular dysfunction.
Circulation 1997;96(9 Suppl):II-253-9.
1997: O S J; Cox M H; Crawford F A; Spinale F G
Protein kinase C activation before cardioplegic arrest: beneficial effects on myocyte contractility.
The Journal of thoracic and cardiovascular surgery 1997;114(4):651-9.
1997: Spinale F G; Mukherjee R; Iannini J P; Whitebread S; Hebbar L; Clair M J; Melton D M; Cox M H; Thomas P B; de Gasparo M
Modulation of the renin-angiotensin pathway through enzyme inhibition and specific receptor blockade in pacing-induced heart failure: II. Effects on myocyte contractile processes.
Circulation 1997;96(7):2397-406.
1997: Spinale F G; de Gasparo M; Whitebread S; Hebbar L; Clair M J; Melton D M; Krombach R S; Mukherjee R; Iannini J P; O S J
Modulation of the renin-angiotensin pathway through enzyme inhibition and specific receptor blockade in pacing-induced heart failure: I. Effects on left ventricular performance and neurohormonal systems.
Circulation 1997;96(7):2385-96.
1997: Dorman B H; Hebbar L; Hinton R B; Roy R C; Spinale F G
Preservation of myocyte contractile function after hyperthermic cardioplegic arrest by activation of ATP-sensitive potassium channels.
Circulation 1997;96(7):2376-84.
1997: Pinosky M L; Kennedy D J; Fishman R L; Reeves S T; Alpert C C; Ecklund J; Kribbs S; Spinale F G; Kratz J M; Crawford R; Gravlee G P; Dorman B H
Tranexamic acid reduces bleeding after cardiopulmonary bypass when compared to epsilon aminocaproic acid and placebo.
Journal of cardiac surgery 1997;12(5):330-8.
1997: Walker J D; Kratz J M; Basler C G; Meck L P; Stratton J R; Kribbs S B; Crawford F A; Spinale F G
Fate of gelatin-resorcinol-formaldehyde/glutaraldeyde adhesive on femoral vessel morphology.
The Journal of surgical research 1997;71(1):73-8.
1997: Wang Z; Lam C F; Mukherjee R; Hebbar L; Wang Y; Spinale F G
Relationship between external load and isolated myocyte contractile function with CHF in pigs.
The American journal of physiology 1997;273(1 Pt 2):H183-91.
1997: Hinton R B; Hebbar L; Cox M H; Mukherjee R; Joshi J D; Crawford F A; Spinale F G
Left ventricular regional myocyte contractility in normal and heart failure states.
Journal of molecular and cellular cardiology 1997;29(7):1939-46.
1997: Cox M H; O S J; de Gasparo M; Mukherjee R; Hewett K W; Spinale F G
Myocardial electrophysiological properties in the presence of an AT1 angiotensin II receptor antagonist.
Basic research in cardiology 1997;92(3):129-38.
1997: Cox M H; O S J; Hebbar L; Mukherjee R; Crawford F A; Spinale F G
Protective effects of adenosine on myocyte contractility during cardioplegic arrest.
The Annals of thoracic surgery 1997;63(4):981-7.
1997: Spinale F G; Walker J D; Mukherjee R; Iannini J P; Keever A T; Gallagher K P
Concomitant endothelin receptor subtype-A blockade during the progression of pacing-induced congestive heart failure in rabbits. Beneficial effects on left ventricular and myocyte function.
Circulation 1997;95(7):1918-29.
1997: Cox M H; O S J; Clair M J; Mukherjee R; Wakefield T W; Andrews P C; Stanley J C; Crawford F A; Spinale F G
Differential effects of novel protamine variants on myocyte contractile function with left ventricular failure.
Surgery 1997;121(3):304-13.
1997: Hebbar L; Dorman B H; Clair M J; Roy R C; Spinale F G
Negative and selective effects of propofol on isolated swine myocyte contractile function in pacing-induced congestive heart failure.
Anesthesiology 1997;86(3):649-59.
1997: Melton D M; Holzgrefe H H; Walker J D; Mukherjee R; Arthur S R; Antonaccio M J; Koster W H; Spinale F G
Effects of chronic angiotensin-converting enzyme inhibition on left ventricular and myocyte structure and function during recovery from chronic rapid pacing.
Journal of molecular and cellular cardiology 1997;29(2):697-710.
1997: Eble D M; Walker J D; Mukherjee R; Samarel A M; Spinale F G
Myosin heavy chain synthesis is increased in a rabbit model of heart failure.
The American journal of physiology 1997;272(2 Pt 2):H969-78.
1996: Thomas P B; Liu E C; Webb M L; Mukherjee R; Hebbar L; Spinale F G
Exogenous effects and endogenous production of endothelin in cardiac myocytes: potential significance in heart failure.
The American journal of physiology 1996;271(6 Pt 2):H2629-37.
1996: Spinale F G; Johnson W S; Wang Y; Wang Z; Mukherjee R; Hebbar L; Jones B U
Direct effects of chronic beta-adrenergic receptor blockade on left ventricular and myocyte function in a model of tachycardia-induced congestive heart failure.
Journal of cardiac failure 1996;2(4):311-8.
1996: Iannini J P; Spinale F G
The identification of contributory mechanisms for the development and progression of congestive heart failure in animal models.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 1996;15(11):1138-50.
1996: O S J; Zellner J L; Cox M H; Hebbar L; Brothers T E; Mukherjee R; Tempel G E; Dorman B H; Crawford F A; Spinale F G
Contributory mechanisms for the beneficial effects of myocyte preconditioning during cardioplegic arrest.
Circulation 1996;94(9 Suppl):II389-97.
1996: Hebbar L; Dorman B H; Roy R C; Spinale F G
The direct effects of propofol on myocyte contractile function after hypothermic cardioplegic arrest.
Anesthesia and analgesia 1996;83(5):949-57.
1996: Handy J R; Dorman B H; Cavallo M J; Hinton R B; Roy R C; Crawford F A; Spinale F G
Direct effects of oxygenated crystalloid or blood cardioplegia on isolated myocyte contractile function.
The Journal of thoracic and cardiovascular surgery 1996;112(4):1064-72.
1996: Spinale F G; Zellner J L; Johnson W S; Eble D M; Munyer P D
Cellular and extracellular remodeling with the development and recovery from tachycardia-induced cardiomyopathy: changes in fibrillar collagen, myocyte adhesion capacity and proteoglycans.
Journal of molecular and cellular cardiology 1996;28(8):1591-608.
1996: McMahon W S; Holzgrefe H H; Walker J D; Mukherjee R; Arthur S R; Cavallo M J; Child M J; Spinale F G
Cellular basis for improved left ventricular pump function after digoxin therapy in experimental left ventricular failure.
Journal of the American College of Cardiology 1996;28(2):495-505.
1996: O S J; Cox M H; Mukherjee R; Clair M J; Crawford F A; Spinale F G
Direct and interactive effects of cardioplegic arrest and protamine on myocyte contractility.
The Annals of thoracic surgery 1996;62(2):489-94.
1996: Reed C E; Dorman B H; Spinale F G
Mechanisms of right ventricular dysfunction after pulmonary resection.
The Annals of thoracic surgery 1996;62(1):225-31; discussion 231-2.
1996: Hansen S B; Slater A D; Rodriguez C A; Spinale F G; Santamore W P
Examination of epimysial leads used to stimulate the latissimus dorsi muscle.
IEEE transactions on bio-medical engineering 1996;43(6):653-7.
1996: McMahon W S; Gillette P C; Hinton R B; Stratton J R; Crawford F A; Spinale F G
Developmental differences in myocyte contractile response after cardioplegic arrest.
The Journal of thoracic and cardiovascular surgery 1996;111(6):1257-66.
1996: Dorman B H; Cavallo M J; Hinton R B; Roy R C; Spinale F G
Preservation of myocyte contractile function after hypothermic, hyperkalemic cardioplegic arrest with 2, 3-butanedione monoxime.
The Journal of thoracic and cardiovascular surgery 1996;111(3):621-9.
1996: Wang Z; Mukherjee R; Lam C F; Spinale F G
Spatial characterization of contracting cardiac myocytes by computer-assisted, video-based image processing.
The American journal of physiology 1996;270(2 Pt 2):H769-79.
1996: McMahon W S; Mukherjee R; Gillette P C; Crawford F A; Spinale F G
Right and left ventricular geometry and myocyte contractile processes with dilated cardiomyopathy: myocyte growth and beta-adrenergic responsiveness.
Cardiovascular research 1996;31(2):314-23.
1996: Zellner J L; Hebbar L; Crawford F A; Mukherjee R; Spinale F G
Beneficial effects of myocyte preconditioning on contractile processes after cardioplegic arrest.
The Annals of thoracic surgery 1996;61(2):558-64.
1996: Mannion J D; Blood V; Bailey W; Bauer T L; Magno M G; DiMeo F; Epple A; Spinale F G
The effect of basic fibroblast growth factor on the blood flow and morphologic features of a latissimus dorsi cardiomyoplasty.
The Journal of thoracic and cardiovascular surgery 1996;111(1):19-28.
1995: Hird R B; Wakefield T W; Mukherjee R; Jones B U; Crawford F A; Andrews P C; Stanley J C; Spinale F G
Direct effects of protamine sulfate on myocyte contractile processes. Cellular and molecular mechanisms.
Circulation 1995;92(9 Suppl):II433-46.
1995: Dorman B H; Cavallo M J; Roy R C; Spinale F G
The direct and interactive effects of phosphodiesterase inhibition and beta-adrenergic stimulation on myocyte contractile function after hypothermic cardioplegic arrest.
Anesthesia and analgesia 1995;81(5):925-31.
1995: Walker J D; Crawford F A; Mukherjee R; Spinale F G
The direct effects of 3,5,3'-triiodo-L-thyronine (T3) on myocyte contractile processes. Insights into mechanisms of action.
The Journal of thoracic and cardiovascular surgery 1995;110(5):1369-79; discussion 1379-80.
1995: Dorman B H; Elliott B M; Spinale F G; Bailey M K; Walton J S; Robison J G; Brothers T E; Cook M H
Protamine use during peripheral vascular surgery: a prospective randomized trial.
Journal of vascular surgery : official publication, the Society for Vascular Surgery [and] International Society for Cardiovascular Surgery, North American Chapter 1995;22(3):248-55; discussion 256.
1995: Kato S; Spinale F G; Tanaka R; Johnson W; Cooper G; Zile M R
Inhibition of collagen cross-linking: effects on fibrillar collagen and ventricular diastolic function.
The American journal of physiology 1995;269(3 Pt 2):H863-8.
1995: Spinale F G
1988: Comparison of bioimpedance and thermodilution methods for determining cardiac output: experimental and clinical studies. Updated in 1995.
The Annals of thoracic surgery 1995;60(2):483-4.
1995: Walker J D; Crawford F A; Spinale F G
3,5,3' Triiodo-L-thyronine pretreatment with cardioplegic arrest and chronic left ventricular dysfunction.
The Annals of thoracic surgery 1995;60(2):292-9.
1995: Walker J D; Crawford F A; Spinale F G
Pretreatment with 3,5,3'triiodo-L-thyronine (T3). Effects on myocyte contractile function after hypothermic cardioplegic arrest and rewarming.
The Journal of thoracic and cardiovascular surgery 1995;110(2):315-27.
1995: Spinale F G; Holzgrefe H H; Mukherjee R; Hird R B; Walker J D; Arnim-Barker A; Powell J R; Koster W H
Angiotensin-converting enzyme inhibition and the progression of congestive cardiomyopathy. Effects on left ventricular and myocyte structure and function.
Circulation 1995;92(3):562-78.
1995: Mukherjee R; Hewett K W; Spinale F G
Myocyte electrophysiological properties following the development of supraventricular tachycardia-induced cardiomyopathy.
Journal of molecular and cellular cardiology 1995;27(6):1333-48.
1995: Eble D M; Spinale F G
Contractile and cytoskeletal content, structure, and mRNA levels with tachycardia-induced cardiomyopathy.
The American journal of physiology 1995;268(6 Pt 2):H2426-39.
1995: Zile M R; Mukherjee R; Clayton C; Kato S; Spinale F G
Effects of chronic supraventricular pacing tachycardia on relaxation rate in isolated cardiac muscle cells.
The American journal of physiology 1995;268(5 Pt 2):H2104-13.
1995: Cavallo M J; Dorman B H; Spinale F G; Roy R C
Myocyte contractile responsiveness after hypothermic, hyperkalemic cardioplegic arrest. Disparity between exogenous calcium and beta-adrenergic stimulation.
Anesthesiology 1995;82(4):926-39.
1995: Hird R B; Crawford F A; Spinale F G
Differential effects of protamine sulfate on myocyte contractile function with left ventricular failure.
Journal of the American College of Cardiology 1995;25(3):773-80.
1995: Spinale F G; Holzgrefe H H; Mukherjee R; Arthur S R; Child M J; Powell J R; Koster W H
LV and myocyte structure and function after early recovery from tachycardia-induced cardiomyopathy.
The American journal of physiology 1995;268(2 Pt 2):H836-47.
1995: Hird R B; Crawford F A; Mukherjee R; Spinale F G
Direct effects of thrombin on myocyte contractile function.
The Annals of thoracic surgery 1995;59(2):288-93.
1994: Hird R B; Spinale F G; Hewett K W; Mukherjee R; Crawford F A
The direct effects of protamine sulfate on myocyte contractile processes.
The Journal of thoracic and cardiovascular surgery 1994;108(6):1100-14.
1994: Walker J D; Crawford F A; Kato S; Spinale F G
The novel effects of 3,5,3'-triiodo-L-thyronine on myocyte contractile function and beta-adrenergic responsiveness in dilated cardiomyopathy.
The Journal of thoracic and cardiovascular surgery 1994;108(4):672-9.
1994: Burkett D E; Seymour A A; Knight D H; Rabon C E; Lanoce V M; Clemons A F; Spinale F G
Myocardial effects of repetitive episodes of rapid ventricular pacing in conscious dogs: surgical creation, echocardiographic evaluation, and morphometric analysis.
Laboratory animal science 1994;44(5):453-61.
1994: Walker J D; Crawford F A; Mukherjee R; Zile M R; Spinale F G
Direct effects of acute administration of 3, 5, 3' triiodo-L-thyronine on myocyte function.
The Annals of thoracic surgery 1994;58(3):851-6.
1994: Spinale F G; Eble D M; Mukherjee R; Johnson W S; Walker J D
Left ventricular and myocyte structure and function following chronic ventricular tachycardia in rabbits.
Basic research in cardiology 1994;89(5):456-67.
1994: Spinale F G; Tempel G E; Mukherjee R; Eble D M; Brown R; Vacchiano C A; Zile M R
Cellular and molecular alterations in the beta adrenergic system with cardiomyopathy induced by tachycardia.
Cardiovascular research 1994;28(8):1243-50.
1994: Tsutsui H; Spinale F G; Nagatsu M; Schmid P G; Ishihara K; DeFreyte G; Cooper G; Carabello B A
Effects of chronic beta-adrenergic blockade on the left ventricular and cardiocyte abnormalities of chronic canine mitral regurgitation.
The Journal of clinical investigation 1994;93(6):2639-48.
1994: Hird R B; Crawford F A; Mukherjee R; Zile M R; Spinale F G
Effects of protamine on myocyte contractile function and beta-adrenergic responsiveness.
The Annals of thoracic surgery 1994;57(5):1066-74; discussion 1074-5.
1994: Handy J R; Spinale F G; Mukherjee R; Crawford F A
Hypothermic potassium cardioplegia impairs myocyte recovery of contractility and inotropy.
The Journal of thoracic and cardiovascular surgery 1994;107(4):1050-8.
1994: Kratz J M; Johnson W S; Mukherjee R; Hu J; Crawford F A; Spinale F G
The relation between latissimus dorsi skeletal muscle structure and contractile function after cardiomyoplasty.
The Journal of thoracic and cardiovascular surgery 1994;107(3):868-78.
1993: Spinale F G; Ishihra K; Zile M; DeFryte G; Crawford F A; Carabello B A
Structural basis for changes in left ventricular function and geometry because of chronic mitral regurgitation and after correction of volume overload.
The Journal of thoracic and cardiovascular surgery 1993;106(6):1147-57.
1993: Tanaka R; Fulbright B M; Mukherjee R; Burchell S A; Crawford F A; Zile M R; Spinale F G
The cellular basis for the blunted response to beta-adrenergic stimulation in supraventricular tachycardia-induced cardiomyopathy.
Journal of molecular and cellular cardiology 1993;25(10):1215-33.
1993: Sutton R G; Kratz J M; Spinale F G; Crawford F A
Comparison of three blood-processing techniques during and after cardiopulmonary bypass.
The Annals of thoracic surgery 1993;56(4):938-43.
1993: Reed C E; Dorman B H; Spinale F G
Assessment of right ventricular contractile performance after pulmonary resection.
The Annals of thoracic surgery 1993;56(3):426-31; discussion 431-2.
1993: Urabe Y; Hamada Y; Spinale F G; Carabello B A; Kent R L; Cooper G; Mann D L
Cardiocyte contractile performance in experimental biventricular volume-overload hypertrophy.
The American journal of physiology 1993;264(5 Pt 2):H1615-23.
1993: Mukherjee R; Crawford F A; Hewett K W; Spinale F G
Cell and sarcomere contractile performance from the same cardiocyte using video microscopy.
Journal of applied physiology (Bethesda, Md. : 1985) 1993;74(4):2023-33.
1993: Cheng W; Michele J J; Spinale F G; Sink J D; Santamore W P
Effects of cardiomyoplasty on biventricular function in canine chronic heart failure.
The Annals of thoracic surgery 1993;55(4):893-901.
1993: Dorman B H; Spinale F G; Bailey M K; Kratz J M; Roy R C
Identification of patients at risk for excessive blood loss during coronary artery bypass surgery: thromboelastography versus coagulation screen.
Anesthesia and analgesia 1993;76(4):694-700.
1993: Zile M R; Tomita M; Ishihara K; Nakano K; Lindroth J; Spinale F; Swindle M; Carabello B A
Changes in diastolic function during development and correction of chronic LV volume overload produced by mitral regurgitation.
Circulation 1993;87(4):1378-88.
1993: Spinale F G; Mukherjee R; Fulbright B M; Hu J; Crawford F A; Zile M R
Contractile properties of isolated porcine ventricular myocytes.
Cardiovascular research 1993;27(2):304-11.
1992: Dorman B H; Spinale F G; Kratz J M; Alpert C C; Ford M
Use of a combined right ventricular ejection fraction-oximetry catheter system for coronary bypass surgery.
Critical care medicine 1992;20(12):1650-6.
1992: Tanaka R; Spinale F G; Crawford F A; Zile M R
Effect of chronic supraventricular tachycardia on left ventricular function and structure in newborn pigs.
Journal of the American College of Cardiology 1992;20(7):1650-60.
1992: Zile M R; Tanaka R; Lindroth J R; Spinale F; Carabello B A; Mirsky I
Left ventricular volume determined echocardiographically by assuming a constant left ventricular epicardial long-axis/short-axis dimension ratio throughout the cardiac cycle.
Journal of the American College of Cardiology 1992;20(4):986-93.
1992: Burchell S A; Spinale F G; Crawford F A; Tanaka R; Zile M R
Effects of chronic tachycardia-induced cardiomyopathy on the beta-adrenergic receptor system.
The Journal of thoracic and cardiovascular surgery 1992;104(4):1006-12.
1992: Douville E C; Kratz J M; Spinale F G; Crawford F A; Alpert C C; Pearce A
Retrograde versus antegrade cardioplegia: impact on right ventricular function.
The Annals of thoracic surgery 1992;54(1):56-61.
1992: Spinale F G; Fulbright B M; Mukherjee R; Tanaka R; Hu J; Crawford F A; Zile M R
Relation between ventricular and myocyte function with tachycardia-induced cardiomyopathy.
Circulation research 1992;71(1):174-87.
1992: Reed C E; Spinale F G; Crawford F A
Effect of pulmonary resection on right ventricular function.
The Annals of thoracic surgery 1992;53(4):578-82.
1992: Spinale F G; Mukherjee R; Tanaka R; Zile M R
The effects of valvular regurgitation on thermodilution ejection fraction measurements.
Chest 1992;101(3):723-31.
1992: Spinale F G; Clayton C; Tanaka R; Fulbright B M; Mukherjee R; Schulte B A; Crawford F A; Zile M R
Myocardial Na+,K(+)-ATPase in tachycardia induced cardiomyopathy.
Journal of molecular and cellular cardiology 1992;24(3):277-94.
1992: Spinale F G; Tanaka R; Crawford F A; Zile M R
Changes in myocardial blood flow during development of and recovery from tachycardia-induced cardiomyopathy.
Circulation 1992;85(2):717-29.
1992: Spinale F G; Grine R C; Tempel G E; Crawford F A; Zile M R
Alterations in the myocardial capillary vasculature accompany tachycardia-induced cardiomyopathy.
Basic research in cardiology 1992;87(1):65-79.
1991: Spinale F G; Crawford F A; Hewett K W; Carabello B A
Ventricular failure and cellular remodeling with chronic supraventricular tachycardia.
The Journal of thoracic and cardiovascular surgery 1991;102(6):874-82.
1991: Spinale F G; Zellner J L; Tomita M; Crawford F A; Zile M R
Relation between ventricular and myocyte remodeling with the development and regression of supraventricular tachycardia-induced cardiomyopathy.
Circulation research 1991;69(4):1058-67.
1991: Zellner J L; Spinale F G; Eble D M; Hewett K W; Crawford F A
Alterations in myocyte shape and basement membrane attachment with tachycardia-induced heart failure.
Circulation research 1991;69(3):590-600.
1991: Spinale F G; Tomita M; Zellner J L; Cook J C; Crawford F A; Zile M R
Collagen remodeling and changes in LV function during development and recovery from supraventricular tachycardia.
The American journal of physiology 1991;261(2 Pt 2):H308-18.
1991: Spinale F G; Zellner J L; Tomita M; Tempel G E; Crawford F A; Zile M R
Tachycardia-induced cardiomyopathy: effects on blood flow and capillary structure.
The American journal of physiology 1991;261(1 Pt 2):H140-8.
1991: Trippel D L; Harold M E; Spinale F G; Buckles D S; Gillette P C
The acute effects of flecainide in the swine heart failing from incessant supraventricular tachycardia.
American heart journal 1991;121(6 Pt 1):1721-6.
1991: Nakano K; Swindle M M; Spinale F; Ishihara K; Kanazawa S; Smith A; Biederman R W; Clamp L; Hamada Y; Zile M R
Depressed contractile function due to canine mitral regurgitation improves after correction of the volume overload.
The Journal of clinical investigation 1991;87(6):2077-86.
1991: Smith A C; Zellner J L; Spinale F G; Swindle M M
Sedative and cardiovascular effects of midazolam in swine.
Laboratory animal science 1991;41(2):157-61.
1991: Spinale F G; Zellner J L; Mukherjee R; Crawford F A
Placement considerations for measuring thermodilution right ventricular ejection fractions.
Critical care medicine 1991;19(3):417-21.
1991: Tomita M; Spinale F G; Crawford F A; Zile M R
Changes in left ventricular volume, mass, and function during the development and regression of supraventricular tachycardia-induced cardiomyopathy. Disparity between recovery of systolic versus diastolic function.
Circulation 1991;83(2):635-44.
1991: Spinale F G; Pearce A P; Schulte B A; Crawford F A
Ventricular function and Na+,K(+)-ATPase activity and distribution with chronic supraventricular tachycardia.
Cardiovascular research 1991;25(2):138-44.
1991: Zellner J L; Spinale F G; Crawford F A; Cook J A
Right ventricular pump dysfunction with acute experimental septic shock.
The Journal of surgical research 1991;50(1):93-9.
1991: Mukherjee R; Spinale F G; von Recum A F; Crawford F A
In vitro validation of a right ventricular thermodilution ejection fraction system.
Annals of biomedical engineering 1991;19(2):165-77.
1991: Swindle M M; Spinale F G; Smith A C; Schumann R E; Green C T; Nakano K; Kanasawa S; Ishihara K; Zile M R; Carabello B A
Anesthetic and postoperative protocols for a canine model of reversible left ventricular volume overload.
Journal of investigative surgery : the official journal of the Academy of Surgical Research 1991;4(3):339-46.
1991: Tarnowski B I; Spinale F G; Nicholson J H
DAPI as a useful stain for nuclear quantitation.
Biotechnic & histochemistry : official publication of the Biological Stain Commission 1991;66(6):297-302.
1990: Spinale F G; Zellner J L; Mukherjee R; Ferris S E; Crawford F A
Thermodilution right ventricular ejection fraction. Catheter positioning effects.
Chest 1990;98(5):1259-65.
1990: Winston D C; Spinale F G; Crawford F A; Schulte B A
Immunocytochemical and enzyme histochemical localization of Na+,K(+)-ATPase in normal and ischemic porcine myocardium.
Journal of molecular and cellular cardiology 1990;22(10):1071-82.
1990: Hendrick D A; Smith A C; Kratz J M; Crawford F A; Spinale F G
The pig as a model of tachycardia and dilated cardiomyopathy.
Laboratory animal science 1990;40(5):495-501.
1990: Spinale F G; Hendrick D A; Crawford F A; Smith A C; Hamada Y; Carabello B A
Chronic supraventricular tachycardia causes ventricular dysfunction and subendocardial injury in swine.
The American journal of physiology 1990;259(1 Pt 2):H218-29.
1990: Spinale F G; Hendrick D A; Crawford F A; Carabello B A
Relationship between bioimpedance, thermodilution, and ventriculographic measurements in experimental congestive heart failure.
Cardiovascular research 1990;24(5):423-9.
1990: Zellner J L; Spinale F G; Crawford F A
Bioimpedance: a novel method for the determination of extravascular lung water.
The Journal of surgical research 1990;48(5):454-9.
1990: Spinale F G; Carabello B A; Crawford F A
Right ventricular function and three-dimensional modeling using computer-aided design.
Journal of applied physiology (Bethesda, Md. : 1985) 1990;68(4):1707-16.
1990: Spinale F G; Smith A C; Crawford F A
Relationship of bioimpedance to thermodilution and echocardiographic measurements of cardiac function.
Critical care medicine 1990;18(4):414-8.
1990: Swindle M M; Thompson R P; Carabello B A; Smith A C; Hepburn B J; Bodison D R; Corin W; Fazel A; Biederman W W; Spinale F G
Heritable ventricular septal defect in Yucatan miniature swine.
Laboratory animal science 1990;40(2):155-61.
1990: Spinale F G; Carabello B A; Schulte B A; Crawford F A
Wavefront myocyte injury and relationship to function in right ventricular ischemia.
The American journal of physiology 1990;258(2 Pt 2):H292-304.
1990: Spinale F G; Smith A C; Carabello B A; Crawford F A
Right ventricular function computed by thermodilution and ventriculography. A comparison of methods.
The Journal of thoracic and cardiovascular surgery 1990;99(1):141-52.
1990: Smith A C; Spinale F G; Swindle M M
Cardiac function and morphology of Hanford miniature swine and Yucatan miniature and micro swine.
Laboratory animal science 1990;40(1):47-50.
1989: Spinale F G; Reines H D; Cook M C; Crawford F A
Noninvasive estimation of extravascular lung water using bioimpedance.
The Journal of surgical research 1989;47(6):535-40.
1989: Leman R B; Spinale F G; Dorn G W; Cooper G; Spann J F; Gillette P C; Carabello B A
Supernormal ejection performance is isolated to the ipsilateral congenitally pressure-overloaded ventricle.
Journal of the American College of Cardiology 1989;13(6):1314-9.
1989: Spinale F G; Schulte B A; Crawford F A
Demonstration of early ischemic injury in porcine right ventricular myocardium.
The American journal of pathology 1989;134(3):693-704.
1989: Spinale F G; Linker R W; Crawford F A; Reines H D
Conventional versus high frequency jet ventilation with a bronchopleural fistula.
The Journal of surgical research 1989;46(2):147-51.
1989: Smith A C; Spinale F G; Carabello B A; Swindle M M
Technical aspects of cardiac catheterization of swine.
Journal of investigative surgery : the official journal of the Academy of Surgical Research 1989;2(2):187-94.
1988: Clevenger F W; Linker R W; Crawford F A; Spinale F G; Reines H D
The use of positive end expiratory pressure to alter systemic-pulmonary shunt flow using conventional and high frequency jet ventilators.
Current surgery 1988;45(3):212-4.
1988: Spinale F G; Reines H D; Crawford F A
Comparison of bioimpedance and thermodilution methods for determining cardiac output: experimental and clinical studies.
The Annals of thoracic surgery 1988;45(4):421-5.
1987: Ullom R L; Sade R M; Crawford F A; Ross B A; Spinale F
The Blalock-Taussig shunt in infants: standard versus modified.
The Annals of thoracic surgery 1987;44(5):539-43.
1986: Crawford F A; Sade R M; Spinale F
Bovine pericardium for correction of congenital heart defects.
The Annals of thoracic surgery 1986;41(6):602-5.

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