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Giatgen Spinas

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Isabelle Aeberli; Philip A Gerber; Michel Hochuli; Stefanie B Murer; Giatgen A Spinas; Lisa Sze; Luc Tappy; Kaspar Berneis
Moderate amounts of fructose consumption impair insulin sensitivity in healthy young men: a randomized controlled trial.
Zuzana Sopkova; Giatgen A Spinas; Radovan Tisko; Kaspar Berneis; Zuzana Dorkova; Manfredi Rizzo; Ruzena Tkacova
Size and subclasses of low-density lipoproteins in patients with obstructive sleep apnea.
Simone Boller; Nicola Boschetti; Flurin Item; Bradley A Joblin; Giatgen A Spinas; Thomas Trüb; Linhua Xu; Markus Niessen
From signal transduction to signal interpretation: an alternative model for the molecular function of insulin receptor substrates.

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2013: Isabelle Aeberli; Philip A Gerber; Michel Hochuli; Stefanie B Murer; Giatgen A Spinas; Lisa Sze; Luc Tappy; Kaspar Berneis
Moderate amounts of fructose consumption impair insulin sensitivity in healthy young men: a randomized controlled trial.
Diabetes care 2013;36(1):150-6.
2012: Zuzana Sopkova; Giatgen A Spinas; Radovan Tisko; Kaspar Berneis; Zuzana Dorkova; Manfredi Rizzo; Ruzena Tkacova
Size and subclasses of low-density lipoproteins in patients with obstructive sleep apnea.
Angiology 2012;63(8):617-21.
2012: Simone Boller; Nicola Boschetti; Flurin Item; Bradley A Joblin; Giatgen A Spinas; Thomas Trüb; Linhua Xu; Markus Niessen
From signal transduction to signal interpretation: an alternative model for the molecular function of insulin receptor substrates.
Archives of physiology and biochemistry 2012;118(3):148-55.
2011: Linhua Xu; Giatgen A Spinas; Markus Niessen
Pro- or anti-inflammatory properties of the adipokine dipeptidyl peptidase-4?
Gastroenterology 2011;141(6):e17.
2011: Peter Wiesli; Cornelia Zwimpfer; Heidi Seiler; Giatgen A Spinas; Heiko Uthoff; René Kindhauser; Aurel Perren; Thomas Pfammatter; Christoph Schmid
Are biochemical markers of neuroendocrine tumors coreleased with insulin following local calcium stimulation in patients with insulinomas?
Pancreas 2011;40(7):995-9.
2011: Dimitri P Mikhailidis; Klaus G Parhofer; Giovam Battista Rini; Manfredi Rizzo; Giatgen A Spinas; Gerald H Tomkin; Alexandros D Tselepis; Anthony S Wierzbicki; Karl Winkler; Alberto Zambon; Vasilios Athyros; Kaspar Berneis; Jacqueline de Graaf; Moses Elisaf; Matilda Florentin; Bruce Griffin; Winfried März; Evangelos Liberopoulos
"European panel on low density lipoprotein (LDL) subclasses": a statement on the pathophysiology, atherogenicity and clinical significance of LDL subclasses: executive summary.
Current vascular pharmacology 2011;9(5):531-2.
2011: Dimitri P Mikhailidis; Klaus G Parhofer; Giovam Battista Rini; Manfredi Rizzo; Giatgen A Spinas; Gerald H Tomkin; Alexandros D Tselepis; Anthony S Wierzbicki; Karl Winkler; Alberto Zambon; Vasilios Athyros; Kaspar Berneis; Jacqueline de Graaf; Moses Elisaf; Matilda Florentin; Bruce Griffin; Winfried März; Evangelos Liberopoulos
"European panel on low density lipoprotein (LDL) subclasses": a statement on the pathophysiology, atherogenicity and clinical significance of LDL subclasses.
Current vascular pharmacology 2011;9(5):533-71.
2011: Isabelle Aeberli; Heiner K Berthold; Philipp A Gerber; Ioanna Gouni-Berthold; Sarah R Haile; Michel Hochuli; Sibylle Kohler; Giatgen A Spinas; Kaspar Berneis
Low to moderate sugar-sweetened beverage consumption impairs glucose and lipid metabolism and promotes inflammation in healthy young men: a randomized controlled trial.
The American journal of clinical nutrition 2011;94(2):479-85.
2010: Manfredi Rizzo; Giatgen A Spinas; Giovam Battista Rini; Kaspar Berneis
Is diabetes the cost to pay for a greater cardiovascular prevention?
International journal of cardiology 2010;144(2):309-10.
2010: Julia H Goedecke; Kristina Utzschneider; Mirjam V Faulenbach; Manfredi Rizzo; Kaspar Berneis; Giatgen A Spinas; Joel A Dave; Naomi S Levitt; Estelle V Lambert; Tommy Olsson; Steven E Kahn
Ethnic differences in serum lipoproteins and their determinants in South African women.
Metabolism: clinical and experimental 2010;59(9):1341-50.
2010: L Xu; Giatgen A Spinas; Markus Niessen
ER stress in adipocytes inhibits insulin signaling, represses lipolysis, and alters the secretion of adipokines without inhibiting glucose transport.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2010;42(9):643-51.
2010: Kaspar Berneis; Manfredi Rizzo; Heiner K Berthold; Giatgen A Spinas; Wilhelm Krone; Ioanna Gouni-Berthold
Ezetimibe alone or in combination with simvastatin increases small dense low-density lipoproteins in healthy men: a randomized trial.
European heart journal 2010;31(13):1633-9.
2010: Francesca Buzzi; Linhua Xu; Richard A Zuellig; Simone B Boller; Giatgen A Spinas; Debby Hynx; Zai Chang; Zhongzhou Yang; Brian A Hemmings; Oliver Tschopp; Markus Niessen
Differential effects of protein kinase B/Akt isoforms on glucose homeostasis and islet mass.
Molecular and cellular biology 2010;30(3):601-12.
2010: Kaspar Berneis; Manfredi Rizzo; J Evans; Giovam Battista Rini; Giatgen A Spinas; J H Goedecke
Interleukin-18 levels are associated with low-density lipoproteins size.
European journal of clinical investigation 2010;40(1):54-5.
2009: Manfredi Rizzo; Giatgen A Spinas; Mustafa Cesur; Zeynep Ozbalkan; Giovam Battista Rini; Kaspar Berneis
Atherogenic lipoprotein phenotype and LDL size and subclasses in drug-naïve patients with early rheumatoid arthritis.
Atherosclerosis 2009;207(2):502-6.
2009: Manfredi Rizzo; Ali A Rizvi; Giatgen A Spinas; Giovam Battista Rini; Kaspar Berneis
Glucose lowering and anti-atherogenic effects of incretin-based therapies: GLP-1 analogues and DPP-4-inhibitors.
Expert opinion on investigational drugs 2009;18(10):1495-503.
2009: Manfredi Rizzo; Kaspar Berneis; Martin Hersberger; Ilenia Pepe; Gaetana Di Fede; Giovam Battista Rini; Giatgen A Spinas; Enrico Carmina
Milder forms of atherogenic dyslipidemia in ovulatory versus anovulatory polycystic ovary syndrome phenotype.
Human reproduction (Oxford, England) 2009;24(9):2286-92.
2009: Michael Brändle; K M Erny-Albrecht; Gordon Goodall; Giatgen A Spinas; P Streit; W J Valentine
Exenatide versus insulin glargine: a cost-effectiveness evaluation in patients with Type 2 diabetes in Switzerland.
International journal of clinical pharmacology and therapeutics 2009;47(8):501-15.
2009: Kaspar Berneis; Manfredi Rizzo; Giatgen A Spinas; Gabriele Di Lorenzo; Gaetana Di Fede; Ilenia Pepe; Vincenzo Pernice; Giovam Battista Rini
The predictive role of atherogenic dyslipidemia in subjects with non-coronary atherosclerosis.
Clinica chimica acta; international journal of clinical chemistry 2009;406(1-2):36-40.
2009: Manfredi Rizzo; Giovam Battista Rini; Giatgen A Spinas; Kaspar Berneis
The effects of ezetimibe on LDL-cholesterol: quantitative or qualitative changes?
Atherosclerosis 2009;204(2):330-3.
2009: Manfredi Rizzo; Vincenzo Pernice; Arian Frasheri; Gabriele Di Lorenzo; Giovam Battista Rini; Giatgen A Spinas; Kaspar Berneis
Small, dense low-density lipoproteins (LDL) are predictors of cardio- and cerebro-vascular events in subjects with the metabolic syndrome.
Clinical endocrinology 2009;70(6):870-5.
2009: Manfredi Rizzo; Kaspar Berneis; Giatgen A Spinas; Giovam Battista Rini; N K Kapur
Quantitative and qualitative effects of rosuvastatin on LDL-cholesterol: what is the clinical significance?
International journal of clinical practice 2009;63(3):478-85.
2009: Isabelle Aeberli; Giatgen A Spinas; Roger Lehmann; Dagmar l'Allemand; Luciano Molinari; Michael B Zimmermann
Diet determines features of the metabolic syndrome in 6- to 14-year-old children.
International journal for vitamin and nutrition research. Internationale Zeitschrift für Vitamin- und Ernährungsforschung. Journal international de vitaminologie et de nutrition 2009;79(1):14-23.
2009: Kaspar Berneis; M Rizzo; Martin Hersberger; G B Rini; G Di Fede; I Pepe; Giatgen A Spinas; Enrico Carmina
Atherogenic forms of dyslipidaemia in women with polycystic ovary syndrome.
International journal of clinical practice 2009;63(1):56-62.
2008: M Rizzo; Kaspar Berneis; A E Altinova; F B Toruner; M Akturk; G Ayvaz; G B Rini; Giatgen A Spinas; M Arslan
Atherogenic lipoprotein phenotype and LDL size and subclasses in women with gestational diabetes.
Diabetic medicine : a journal of the British Diabetic Association 2008;25(12):1406-11.
2008: Isabelle Aeberli; N Beljean; Roger Lehmann; D I'Allemand; Giatgen A Spinas; Michael B Zimmermann
The increase of fatty acid-binding protein aP2 in overweight and obese children: interactions with dietary fat and impact on measures of subclinical inflammation.
International journal of obesity (2005) 2008;32(10):1513-20.
2008: Manfredi Rizzo; Emanuel R Christ; Giovam Battista Rini; Giatgen A Spinas; Kaspar Berneis
The differential effects of thiazolidindiones on atherogenic dyslipidemia in type 2 diabetes: what is the clinical significance?
Expert opinion on pharmacotherapy 2008;9(13):2295-303.
2008: Roger Lehmann; Giatgen A Spinas; Wolfgang Moritz; Markus Weber
Has time come for new goals in human islet transplantation?
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2008;8(6):1096-100.
2008: Beat Schwegler; Katrin D M Stumpe; D Weishaupt; Klaus Strobel; Giatgen A Spinas; G K von Schulthess; J Hodler; T Böni; M Y Donath
Unsuspected osteomyelitis is frequent in persistent diabetic foot ulcer and better diagnosed by MRI than by 18F-FDG PET or 99mTc-MOAB.
Journal of internal medicine 2008;263(1):99-106.
2008: P A Gerber; Vojtech Pavlicek; Nicolas Demartines; Richard A Zuellig; T Pfammatter; R Wüthrich; Markus Weber; Giatgen A Spinas; Roger Lehmann
Simultaneous islet-kidney vs pancreas-kidney transplantation in type 1 diabetes mellitus: a 5 year single centre follow-up.
Diabetologia 2008;51(1):110-9.
2007: Isabelle Aeberli; Ralf Biebinger; Roger Lehmann; Dagmar l'Allemand; Giatgen A Spinas; Michael B Zimmermann
Serum retinol-binding protein 4 concentration and its ratio to serum retinol are associated with obesity and metabolic syndrome components in children.
The Journal of clinical endocrinology and metabolism 2007;92(11):4359-65.
2007: Isabelle Aeberli; Michael B Zimmermann; Luciano Molinari; Roger Lehmann; Dagmar l'Allemand; Giatgen A Spinas; Kaspar Berneis
Fructose intake is a predictor of LDL particle size in overweight schoolchildren.
The American journal of clinical nutrition 2007;86(4):1174-8.
2007: Roger Lehmann; Richard A Zuellig; Patrick Kugelmeier; Philipp B Baenninger; Wolfgang Moritz; Aurel Perren; Pierre-Alain Clavien; Markus Weber; Giatgen A Spinas
Superiority of small islets in human islet transplantation.
Diabetes 2007;56(3):594-603.
2007: Markus Niessen; Frank Jaschinski; Flurin Item; Morgan P McNamara; Giatgen A Spinas; Thomas Trüb
Insulin receptor substrates 1 and 2 but not Shc can activate the insulin receptor independent of insulin and induce proliferation in CHO-IR cells.
Experimental cell research 2007;313(4):805-15.
2007: Emanuela Borter; Markus Niessen; Richard A Zuellig; Giatgen A Spinas; Patrick Spielmann; Gieri Camenisch; Roland H Wenger
Glucose-stimulated insulin production in mice deficient for the PAS kinase PASKIN.
Diabetes 2007;56(1):113-7.
2006: Peter Wiesli; R Lehmann; Pierre-Alexandre Krayenbuehl; Christoph Schmid; Giatgen A Spinas
Assessment of basal insulin requirement using fasting tests in insulin-treated patients with type 2 diabetes mellitus.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2006;114(10):539-43.
2006: Isabelle Aeberli; Luciano Molinari; Giatgen A Spinas; Roger Lehmann; Dagmar l'Allemand; Michael B Zimmermann
Dietary intakes of fat and antioxidant vitamins are predictors of subclinical inflammation in overweight Swiss children.
The American journal of clinical nutrition 2006;84(4):748-55.
2006: Andrew J Palmer; Stéphane Roze; William J Valentine; Joshua A Ray; Andreas Frei; Michel Burnier; Bernhard Hess; Giatgen A Spinas; Michael Brändle
Health economic implications of irbesartan plus conventional antihypertensive medications versus conventional blood pressure control alone in patients with type 2 diabetes, hypertension, and renal disease in Switzerland.
Swiss medical weekly 2006;136(21-22):346-52.
2006: Monika K Wälti; Thomas Walczyk; Michael B Zimmermann; G Fortunato; M Weber; Giatgen A Spinas; Richard F Hurrell
Urinary excretion of an intravenous 26Mg dose as an indicator of marginal magnesium deficiency in adults.
European journal of clinical nutrition 2006;60(2):147-54.
2005: Edwin Straumann; David J Kurz; Jörg Muntwyler; Irene Stettler; Marcel Furrer; Barbara Naegeli; Jürgen Frielingsdorf; Ernst Schuiki; Raymond Mury; Osmund Bertel; Giatgen A Spinas
Admission glucose concentrations independently predict early and late mortality in patients with acute myocardial infarction treated by primary or rescue percutaneous coronary intervention.
American heart journal 2005;150(5):1000-6.
2005: Joachim Størling; J Binzer; Annika K Andersson; R A Züllig; Morten Tonnesen; R Lehmann; Giatgen A Spinas; Stellan Sandler; Nils Billestrup; Thomas Mandrup-Poulsen
Nitric oxide contributes to cytokine-induced apoptosis in pancreatic beta cells via potentiation of JNK activity and inhibition of Akt.
Diabetologia 2005;48(10):2039-50.
2005: I Amacker-Françoys; S Mohanty; Markus Niessen; Giatgen A Spinas; Thomas Trüb
The metabolisable hexoses D-glucose and D-mannose enhance the expression of IRS-2 but not of IRS-1 in pancreatic beta-cells.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2005;113(8):423-9.
2005: Peter Wiesli; Christoph Schmid; Oranna Kerwer; Christel Nigg-Koch; Richard Klaghofer; Burkhardt Seifert; Giatgen A Spinas; Kyrill Schwegler
Acute psychological stress affects glucose concentrations in patients with type 1 diabetes following food intake but not in the fasting state.
Diabetes care 2005;28(8):1910-5.
2005: Roger Lehmann; Vojtech Pavlicek; Giatgen A Spinas; Markus Weber
[Islet transplantation in type I diabetes mellitus].
Therapeutische Umschau. Revue thérapeutique 2005;62(7):481-6.
2005: Peter Wiesli; Beat Schwegler; Beat Schmid; Giatgen A Spinas; Christoph Schmid
Mini-Mental State Examination is superior to plasma glucose concentrations in monitoring patients with suspected hypoglycaemic disorders during the 72-hour fast.
European journal of endocrinology / European Federation of Endocrine Societies 2005;152(4):605-10.
2005: S Mohanty; Giatgen A Spinas; Kathrin Maedler; Richard A Zuellig; R Lehmann; Marc Y Donath; Thomas Trüb; Markus Niessen
Overexpression of IRS2 in isolated pancreatic islets causes proliferation and protects human beta-cells from hyperglycemia-induced apoptosis.
Experimental cell research 2005;303(1):68-78.
2004: Peter Wiesli; Michael Brändle; Christoph Schmid; Lukas Krähenbühl; Jürg Furrer; Ulrich Keller; Giatgen A Spinas; Thomas Pfammatter
Selective arterial calcium stimulation and hepatic venous sampling in the evaluation of hyperinsulinemic hypoglycemia: potential and limitations.
Journal of vascular and interventional radiology : JVIR 2004;15(11):1251-6.
2004: Peter Wiesli; Christoph Schmid; Aurel Perren; Thomas Pfammatter; Giatgen A Spinas; Ulrich Keller
Hypoglycemia in response to glucose and glucagon in insulinoma patients with a negative prolonged fast: functional and morphological properties.
Journal of endocrinological investigation 2004;27(9):832-8.
2004: Peter Wiesli; Aurel Perren; Parvin Saremaslani; Thomas Pfammatter; Giatgen A Spinas; Christoph Schmid
Abnormalities of proinsulin processing in functioning insulinomas: clinical implications.
Clinical endocrinology 2004;61(4):424-30.
2004: Andrew J Palmer; Stéphane Roze; William J Valentine; Michael E Minshall; Morten Lammert; Lars Nicklasson; Giatgen A Spinas
Deleterious effects of increased body weight associated with intensive insulin therapy for type 1 diabetes: increased blood pressure and worsened lipid profile partially negate improvements in life expectancy.
Current medical research and opinion 2004;20 Suppl 1():S67-73.
2004: Andrew J Palmer; Stéphane Roze; William J Valentine; Michael E Minshall; Morten Lammert; Alan Oglesby; Clarice Hayes; Giatgen A Spinas
What impact would pancreatic beta-cell preservation have on life expectancy, quality-adjusted life expectancy and costs of complications in patients with type 2 diabetes? A projection using the CORE Diabetes Model.
Current medical research and opinion 2004;20 Suppl 1():S59-66.
2004: Andrew J Palmer; Stéphane Roze; William J Valentine; Michael E Minshall; Clarice Hayes; Alan Oglesby; Giatgen A Spinas
Impact of changes in HbA1c, lipids and blood pressure on long-term outcomes in type 2 diabetes patients: an analysis using the CORE Diabetes Model.
Current medical research and opinion 2004;20 Suppl 1():S53-8.
2004: Andrew J Palmer; Stéphane Roze; Morten Lammert; William J Valentine; Michael E Minshall; Lars Nicklasson; Mari-Anne Gall; Giatgen A Spinas
Comparing the long-term cost-effectiveness of repaglinide plus metformin versus nateglinide plus metformin in type 2 diabetes patients with inadequate glycaemic control: an application of the CORE Diabetes Model in type 2 diabetes.
Current medical research and opinion 2004;20 Suppl 1():S41-51.
2004: Andrew J Palmer; Stéphane Roze; William J Valentine; Michael E Minshall; Volker Foos; Francesco M Lurati; Morten Lammert; Giatgen A Spinas
Validation of the CORE Diabetes Model against epidemiological and clinical studies.
Current medical research and opinion 2004;20 Suppl 1():S27-40.
2004: Andrew J Palmer; Stéphane Roze; William J Valentine; Michael E Minshall; Volker Foos; Francesco M Lurati; Morten Lammert; Giatgen A Spinas
The CORE Diabetes Model: Projecting long-term clinical outcomes, costs and cost-effectiveness of interventions in diabetes mellitus (types 1 and 2) to support clinical and reimbursement decision-making.
Current medical research and opinion 2004;20 Suppl 1():S5-26.
2004: Peter Wiesli; Michael Brändle; Thomas Pfammatter; Jürgen Zapf; Giatgen A Spinas; Christoph Schmid
Insulin determination by specific and unspecific immunoassays in patients with insulinoma evaluated by the arterial stimulation and venous sampling test.
European journal of endocrinology / European Federation of Endocrine Societies 2004;151(1):123-6.
2004: Kathrin Maedler; Joachim Størling; Jeppe Sturis; Richard A Zuellig; Giatgen A Spinas; Per O G Arkhammar; Thomas Mandrup-Poulsen; Marc Y Donath
Glucose- and interleukin-1beta-induced beta-cell apoptosis requires Ca2+ influx and extracellular signal-regulated kinase (ERK) 1/2 activation and is prevented by a sulfonylurea receptor 1/inwardly rectifying K+ channel 6.2 (SUR/Kir6.2) selective potassium channel opener in human islets.
Diabetes 2004;53(7):1706-13.
2004: Peter Wiesli; Michael Brändle; Jürgen Zapf; Heidi Seiler; Cornelia Zwimpfer; Giatgen A Spinas; Christoph Schmid
Assessment of hyperinsulinaemia at the termination of the prolonged fast.
Clinica chimica acta; international journal of clinical chemistry 2004;342(1-2):227-31.
2004: Irmgard Schmitt-Koopmann; Matthias Schwenkglenks; Giatgen A Spinas; Thomas D Szucs
Direct medical costs of type 2 diabetes and its complications in Switzerland.
European journal of public health 2004;14(1):3-9.
2004: Andrew J Palmer; Stéphane Roze; William J Valentine; Giatgen A Spinas; Jonathan E Shaw; Paul Z Zimmet
Intensive lifestyle changes or metformin in patients with impaired glucose tolerance: modeling the long-term health economic implications of the diabetes prevention program in Australia, France, Germany, Switzerland, and the United Kingdom.
Clinical therapeutics 2004;26(2):304-21.
2003: Peter Wiesli; Beat Schwegler; Giatgen A Spinas; Christoph Schmid
Serum cystatin C is sensitive to small changes in thyroid function.
Clinica chimica acta; international journal of clinical chemistry 2003;338(1-2):87-90.
2003: Monika K Wälti; Michael B Zimmermann; Thomas Walczyk; Giatgen A Spinas; Richard F Hurrell
Measurement of magnesium absorption and retention in type 2 diabetic patients with the use of stable isotopes.
The American journal of clinical nutrition 2003;78(3):448-53.
2003: R Lehmann; RA Honegger; C Feinle; Michael Fried; Giatgen A Spinas; Werner Schwizer
Glucose control is not improved by accelerating gastric emptying in patients with type 1 diabetes mellitus and gastroparesis. a pilot study with cisapride as a model drug.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2003;111(5):255-61.
2003: Monika K Wälti; Michael B Zimmermann; Giatgen A Spinas; Richard F Hurrell
Low plasma magnesium in type 2 diabetes.
Swiss medical weekly 2003;133(19-20):289-92.
2003: Kathrin Maedler; José Oberholzer; Pascal Bucher; Giatgen A Spinas; Marc Y Donath
Monounsaturated fatty acids prevent the deleterious effects of palmitate and high glucose on human pancreatic beta-cell turnover and function.
Diabetes 2003;52(3):726-33.
2002: Peter Wiesli; Michael Brändle; Beat Schwegler; R Lehmann; Giatgen A Spinas; Christoph Schmid
A plasma glucose concentration below 2.5 mmol L-1 is not an appropriate criterion to end the 72-h fast.
Journal of internal medicine 2002;252(6):504-9.
2002: Peter Wiesli; Giatgen A Spinas; T Pfammatter; L Krahenbuhl; Christoph Schmid
Glucose-induced hypoglycaemia.
Lancet 2002;360(9344):1476.
2002: Kathrin Maedler; Pavel Sergeev; Frédéric Ris; José Oberholzer; Helen I Joller-Jemelka; Giatgen A Spinas; Nurit Kaiser; Philippe A Halban; Marc Y Donath
Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets.
The Journal of clinical investigation 2002;110(6):851-60.
2002: Beat Schwegler; T Böni; Jürg Furrer; Giatgen A Spinas; Roger Lehmann
[Practical management of diabetic foot].
Therapeutische Umschau. Revue thérapeutique 2002;59(8):435-42.
2002: Michael Brändle; Giatgen A Spinas
[Management of cardiovascular risk factors in type 2 diabetes mellitus].
Therapeutische Umschau. Revue thérapeutique 2002;59(8):415-21.
2002: P Wiesli; Giatgen A Spinas
[General insulin therapy practice in type 2 diabetes mellitus].
Therapeutische Umschau. Revue thérapeutique 2002;59(8):402-9.
2002: Marc Y Donath; Kathrin Maedler; Pavel Sergeev; Daniela Dyntar; D Thomas; Giatgen A Spinas
[The pathogenesis of type 2 diabetes--new aspects and clinical consequences].
Therapeutische Umschau. Revue thérapeutique 2002;59(8):381-5.
2002: Giatgen A Spinas
[Type 2 diabetes: an equivalent of coronary heart disease].
Therapeutische Umschau. Revue thérapeutique 2002;59(8):379.
2002: Kathrin Maedler; Adriano Fontana; Frédéric Ris; Pavel Sergeev; Christian Toso; José Oberholzer; Roger Lehmann; Felix Bachmann; Andrea Tasinato; Giatgen A Spinas; Philippe A Halban; Marc Y Donath
FLIP switches Fas-mediated glucose signaling in human pancreatic beta cells from apoptosis to cell replication.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(12):8236-41.
2002: Monika K Wälti; Michael B Zimmermann; Giatgen A Spinas; S Jacob; Richard F Hurrell
Dietary magnesium intake in type 2 diabetes.
European journal of clinical nutrition 2002;56(5):409-14.
2001: Michael Brändle; T Pfammatter; Giatgen A Spinas; R Lehmann; Christoph Schmid
Assessment of selective arterial calcium stimulation and hepatic venous sampling to localize insulin-secreting tumours.
Clinical endocrinology 2001;55(3):357-62.
2001: Daniela Dyntar; Monika Eppenberger-Eberhardt; Kathrin Maedler; M Pruschy; Hans M Eppenberger; Giatgen A Spinas; Marc Y Donath
Glucose and palmitic acid induce degeneration of myofibrils and modulate apoptosis in rat adult cardiomyocytes.
Diabetes 2001;50(9):2105-13.
2001: Kathrin Maedler; Giatgen A Spinas; R Lehmann; Pavel Sergeev; M Weber; A Fontana; Nurit Kaiser; Marc Y Donath
Glucose induces beta-cell apoptosis via upregulation of the Fas receptor in human islets.
Diabetes 2001;50(8):1683-90.
2001: Michael Brändle; R Lehmann; F E Maly; Christoph Schmid; Giatgen A Spinas
Diminished insulin secretory response to glucose but normal insulin and glucagon secretory responses to arginine in a family with maternally inherited diabetes and deafness caused by mitochondrial tRNA(LEU(UUR)) gene mutation.
Diabetes care 2001;24(7):1253-8.
2001: Thomas Clerici; C Schmid; P Komminoth; Jochen Lange; Giatgen A Spinas; Michael Brändle
10 Swiss kindreds with multiple endocrine neoplasia type 1: assessment of screening methods.
Swiss medical weekly 2001;131(25-26):381-6.
2001: Kathrin Maedler; Giatgen A Spinas; Daniela Dyntar; Wolfgang Moritz; Nurit Kaiser; Marc Y Donath
Distinct effects of saturated and monounsaturated fatty acids on beta-cell turnover and function.
Diabetes 2001;50(1):69-76.
2000: R Lehmann; Giatgen A Spinas
[Screening, diagnosis and management of diabetes mellitus and diabetic complications].
Therapeutische Umschau. Revue thérapeutique 2000;57(1):12-21.
1999: J Borovicka; R Lehmann; Patrik Kunz; R Fraser; C Kreiss; Gérard R Crelier; Peter Boesiger; Giatgen A Spinas; Michael Fried; Werner Schwizer
Evaluation of gastric emptying and motility in diabetic gastroparesis with magnetic resonance imaging: effects of cisapride.
The American journal of gastroenterology 1999;94(10):2866-73.
1999: Daniele Perucchini; U Fischer; Giatgen A Spinas; Renate Huch; A Huch; R Lehmann
Using fasting plasma glucose concentrations to screen for gestational diabetes mellitus: prospective population based study.
BMJ (Clinical research ed.) 1999;319(7213):812-5.
1999: C Eggenberger; Michael Brändle; Renato L Galeazzi; Giatgen A Spinas; C Schmid
[Cushing syndrome due to ectopic ACTH secretion: an uncommon case presentation, diagnosis and therapy].
Schweizerische medizinische Wochenschrift 1999;129(23):890-5.
1999: Michael Brändle; P Ammann; Giatgen A Spinas; Fabrizio Dutly; Renato L Galeazzi; Christoph Schmid; Martin Altwegg
Relapsing Whipple's disease presenting with hypopituitarism.
Clinical endocrinology 1999;50(3):399-403.
1998: Giatgen A Spinas
[United Kingdom Prospective Diabetes Study: facts and questions].
Schweizerische medizinische Wochenschrift 1998;128(51-52):2043-6.
1998: Giatgen A Spinas; R Laffranchi; I Francoys; Ivana David; C Richter; Manfred Reinecke
The early phase of glucose-stimulated insulin secretion requires nitric oxide.
Diabetologia 1998;41(3):292-9.
1997: R Laffranchi; Giatgen A Spinas
Interferon-gamma inhibits insulin release and induces cell death in the pancreatic beta-cell line INS-1 independently of nitric oxide production.
Experimental cell research 1997;237(1):217-22.
1997: R Lehmann; Vladimir Kaplan; Roland Bingisser; Konrad E Bloch; Giatgen A Spinas
Impact of physical activity on cardiovascular risk factors in IDDM.
Diabetes care 1997;20(10):1603-11.
1997: R Laffranchi; Gabriele Schoedon; N Blau; Giatgen A Spinas
Tetrahydrobiopterin synthesis precedes nitric oxide-dependent inhibition of insulin secretion in INS-1 rat pancreatic beta-cells.
Biochemical and biophysical research communications 1997;233(1):66-70.
1996: R Lehmann; J Borovicka; Patrik Kunz; Gérard R Crelier; Peter Boesiger; Michael Fried; Werner Schwizer; Giatgen A Spinas
Evaluation of delayed gastric emptying in diabetic patients with autonomic neuropathy by a new magnetic resonance imaging technique and radio-opaque markers.
Diabetes care 1996;19(10):1075-82.
1996: R Laffranchi; Giatgen A Spinas
Interleukin 10 inhibits insulin release from and nitric oxide production in rat pancreatic islets.
European journal of endocrinology / European Federation of Endocrine Societies 1996;135(3):374-8.
1995: R Laffranchi; V Gogvadze; Christoph Richter; Giatgen A Spinas
Nitric oxide (nitrogen monoxide, NO) stimulates insulin secretion by inducing calcium release from mitochondria.
Biochemical and biophysical research communications 1995;217(2):584-91.
1995: R Lehmann; A Vokac; K Niedermann; K Agosti; Giatgen A Spinas
Loss of abdominal fat and improvement of the cardiovascular risk profile by regular moderate exercise training in patients with NIDDM.
Diabetologia 1995;38(11):1313-9.