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Margarethe Spindler-Barth

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S Schauer; T Burster; Margarethe Spindler-Barth
N- and C-terminal degradation of ecdysteroid receptor isoforms, when transiently expressed in mammalian CHO cells, is regulated by the proteasome and cysteine and threonine proteases.
S Schauer; A Azoitei; S Braun; Margarethe Spindler-Barth
Influence of hormone response elements (HREs) on ecdysteroid receptor concentration.
Ch Tremmel; A Azoitei; H Hollmann; M Schaefer; Margarethe Spindler-Barth
Influence of helix 12 of Ultraspiracle on Drosophila melanogaster ecdysone receptor function.

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All Publications

2012: S Schauer; T Burster; Margarethe Spindler-Barth
N- and C-terminal degradation of ecdysteroid receptor isoforms, when transiently expressed in mammalian CHO cells, is regulated by the proteasome and cysteine and threonine proteases.
Insect molecular biology 2012;21(3):383-94.
2011: S Schauer; A Azoitei; S Braun; Margarethe Spindler-Barth
Influence of hormone response elements (HREs) on ecdysteroid receptor concentration.
Insect molecular biology 2011;20(6):701-11.
2011: Ch Tremmel; A Azoitei; H Hollmann; M Schaefer; Margarethe Spindler-Barth
Influence of helix 12 of Ultraspiracle on Drosophila melanogaster ecdysone receptor function.
Insect molecular biology 2011;20(4):417-28.
2011: Sebastian Schauer; Jenna Callender; Vincent C Henrich; Margarethe Spindler-Barth
The N-terminus of ecdysteroid receptor isoforms and ultraspiracle interacts with different ecdysteroid response elements in a sequence specific manner to modulate transcriptional activity.
The Journal of steroid biochemistry and molecular biology 2011;124(3-5):84-92.
2011: Ch Tremmel; M Schaefer; A Azoitei; H Ruff; Margarethe Spindler-Barth
Interaction of the N-terminus of ecdysone receptor isoforms with the ligand-binding domain.
Molecular and cellular endocrinology 2011;332(1-2):293-300.
2011: Katarzyna Betanska; Celine Hönl; Margarethe Spindler-Barth; Klaus-Dieter Spindler
The importance of exportin and Ran for nucleocytoplasmic shuttling of the ecdysteroid receptor.
Archives of insect biochemistry and physiology 2011;76(1):12-21.
2009: Klaus-Dieter Spindler; C Hönl; Ch Tremmel; S Braun; H Ruff; Margarethe Spindler-Barth
Ecdysteroid hormone action.
Cellular and molecular life sciences : CMLS 2009;66(24):3837-50.
2009: Simone Braun; Anca Azoitei; Margarethe Spindler-Barth
DNA-binding properties of Drosophila ecdysone receptor isoforms and their modification by the heterodimerization partner ultraspiracle.
Archives of insect biochemistry and physiology 2009;72(3):172-91.
2009: Katarzyna Betanska; Susan Czogalla; Margarethe Spindler-Barth; Klaus-Dieter Spindler
Influence of cell cycle on ecdysteroid receptor in CHO-K1 cells.
Archives of insect biochemistry and physiology 2009;72(3):142-53.
2009: Heike Ruff; Christian Tremmel; Margarethe Spindler-Barth
Transcriptional activity of ecdysone receptor isoforms is regulated by modulation of receptor stability and interaction with Ab- and C-domains of the heterodimerization partner ultraspiracle.
Archives of insect biochemistry and physiology 2009;72(3):154-71.
2009: Joshua M Beatty; Guy Smagghe; Takehiko Ogura; Yoshiaki Nakagawa; Margarethe Spindler-Barth; Vincent C Henrich
Properties of ecdysteroid receptors from diverse insect species in a heterologous cell culture system--a basis for screening novel insecticidal candidates.
The FEBS journal 2009;276(11):3087-98.
2009: Anca Azoitei; Margarethe Spindler-Barth
DNA affects ligand binding of the ecdysone receptor of Drosophila melanogaster.
Molecular and cellular endocrinology 2009;303(1-2):91-9.
2008: Claudia Nieva; Margarethe Spindler-Barth; Klaus-Dieter Spindler
Impact of heterodimerization on intracellular localization of the ecdysteroid receptor (EcR).
Archives of insect biochemistry and physiology 2008;68(1):40-8.
2007: Claudia Nieva; Margarethe Spindler-Barth; Anca Azoitei; Klaus-Dieter Spindler
Influence of hormone on intracellular localization of the Drosophila melanogaster ecdysteroid receptor (EcR).
Cellular signalling 2007;19(12):2582-7.
2007: Katarzyna Betanska; Claudia Nieva; Margarethe Spindler-Barth; Klaus-Dieter Spindler
Nucleocytoplasmic shuttling of the ecdysteroid receptor (EcR) and of ultraspiracle (Usp) from Drosophila melanogaster in mammalian cells: energy requirement and interaction with exportin.
Archives of insect biochemistry and physiology 2007;65(3):134-42.
2007: Marcus V Cronauer; S Braun; Ch Tremmel; Klaus-Dietrich Kröncke; Margarethe Spindler-Barth
Nuclear localization and DNA binding of ecdysone receptor and ultraspiracle.
Archives of insect biochemistry and physiology 2007;65(3):125-33.
2007: Tomasz Gwóźdź; Joanna Dutko-Gwóźdź; Claudia Nieva; Katarzyna Betańska; Marek Orłowski; Agnieszka Kowalska; Jurek Dobrucki; Margarethe Spindler-Barth; Klaus-Dieter Spindler; Andrzej Ozyhar
EcR and Usp, components of the ecdysteroid nuclear receptor complex, exhibit differential distribution of molecular determinants directing subcellular trafficking.
Cellular signalling 2007;19(3):490-503.
2006: J Beatty; Torsten Fauth; J L Callender; Margarethe Spindler-Barth; Vincent C Henrich
Analysis of transcriptional activity mediated by Drosophila melanogaster ecdysone receptor isoforms in a heterologous cell culture system.
Insect molecular biology 2006;15(6):785-95.
2006: M Szécsi; Margarethe Spindler-Barth
Flash labeling of a nuclear receptor domain (D domain of ultraspiracle) fused to tetracysteine tag.
Acta biologica Hungarica 2006;57(2):181-90.
2005: Claudia Nieva; Tomasz Gwóźdź; Joanna Dutko-Gwóźdź; Joerg Wiedenmann; Margarethe Spindler-Barth; Elzbieta Wieczorek; Jurek Dobrucki; Danuta Duś; Vincent C Henrich; Andrzej Ozyhar; Klaus-Dieter Spindler
Ultraspiracle promotes the nuclear localization of ecdysteroid receptor in mammalian cells.
Biological chemistry 2005;386(5):463-70.
2005: B Greb-Markiewicz; Torsten Fauth; Margarethe Spindler-Barth
Ligand binding is without effect on complex formation of the ligand binding domain of the ecdysone receptor (EcR).
Archives of insect biochemistry and physiology 2005;59(1):1-11.
2005: Michael Burret; Jean-Luc Boevé; Alison Barker; Margarethe Spindler-Barth
Structure and mechanical strength of larval cuticle of sawflies capable of "easy bleeding" a defence strategy against predators evolved in Tenthredinidae (Hymenoptera).
Tissue & cell 2005;37(1):67-74.
2004: Marco Grebe; Torsten Fauth; Margarethe Spindler-Barth
Dynamic of ligand binding to Drosophila melanogaster ecdysteroid receptor.
Insect biochemistry and molecular biology 2004;34(9):981-9.
2004: Sabina Przibilla; William W Hitchcock; Mihaly Szécsi; Marco Grebe; Joshua Beatty; Vincent C Henrich; Margarethe Spindler-Barth
Functional studies on the ligand-binding domain of Ultraspiracle from Drosophila melanogaster.
Biological chemistry 2004;385(1):21-30.
2003: Marco Grebe; Sabina Przibilla; Vincent C Henrich; Margarethe Spindler-Barth
Characterization of the ligand-binding domain of the ecdysteroid receptor from Drosophila melanogaster.
Biological chemistry 2003;384(1):105-16.
2002: Markus Lezzi; Thomas Bergman; Vincent C Henrich; Martin Vögtli; Christina Frömel; Marco Grebe; Sabina Przibilla; Margarethe Spindler-Barth
Ligand-induced heterodimerization between the ligand binding domains of the Drosophila ecdysteroid receptor and ultraspiracle.
European journal of biochemistry / FEBS 2002;269(13):3237-45.
2002: Marco Grebe; Margarethe Spindler-Barth
Expression of ecdysteroid receptor and ultraspiracle from Chironomus tentans (Insecta, Diptera) in E. coli and purification in a functional state.
Insect biochemistry and molecular biology 2002;32(2):167-74.
2000: Vincent C Henrich; M E Vogtli; Christophe Antoniewski; Margarethe Spindler-Barth; Sabina Przibilla; Maher A Noureddine; Markus Lezzi
Developmental effects of a chimeric ultraspiracle gene derived from Drosophila and Chironomus.
Genesis (New York, N.Y. : 2000) 2000;28(3-4):125-33.
2000: M Feix; S Glöggler; M Londershausen; Wolfgang Weidemann; Klaus-Dieter Spindler; Margarethe Spindler-Barth
A cDNA encoding a chitinase from the epithelial cell line of chironomus tentans (Insecta, diptera) and its functional expression.
Archives of insect biochemistry and physiology 2000;45(1):24-36.
2000: Marco Grebe; P Rauch; Margarethe Spindler-Barth
Characterization of subclones of the epithelial cell line from Chironomus tentans resistant to the insecticide RH 5992, a non-steroidal moulting hormone agonist.
Insect biochemistry and molecular biology 2000;30(7):591-600.
1999: Martin Vögtli; M O Imhof; N E Brown; P Rauch; Margarethe Spindler-Barth; Markus Lezzi; Vincent C Henrich
Functional characterization of two Ultraspiracle forms (CtUSP-1 and CtUSP-2) from Chironomus tentans.
Insect biochemistry and molecular biology 1999;29(10):931-42.
1999: Klaus-Dieter Spindler; Margarethe Spindler-Barth
Inhibitors of chitinases.
EXS 1999;87():201-9.
1999: C Elke; P Rauch; Margarethe Spindler-Barth; Klaus-Dieter Spindler
DNA-binding properties of the ecdysteroid receptor-complex (EcR/USP) of the epithelial cell line from Chironomus tentans.
Archives of insect biochemistry and physiology 1999;41(3):124-33.
1998: P Rauch; Marco Grebe; C Elke; Klaus-Dieter Spindler; Margarethe Spindler-Barth
Ecdysteroid receptor and ultraspiracle from Chironomus tentans (Insecta) are phosphoproteins and are regulated differently by molting hormone.
Insect biochemistry and molecular biology 1998;28(4):265-75.
1998: M Lammerding-Köppel; Margarethe Spindler-Barth; E Steiner; Markus Lezzi; Ulrich Drews; Klaus-Dieter Spindler
Immunohistochemical localization of ecdysteroid receptor and ultraspiracle in the epithelial cell line from Chironomus tentans (Insecta, Diptera).
Tissue & cell 1998;30(2):187-94.
1998: Margarethe Spindler-Barth; Klaus-Dieter Spindler
Ecdysteroid resistant subclones of the epithelial cell line from Chironomus tentans (Insecta, Diptera). I. Selection and characterization of resistant clones.
In vitro cellular & developmental biology. Animal 1998;34(2):116-22.
1997: Klaus-Dieter Spindler; Margarethe Spindler-Barth; S Sakuda
Effect of demethylation on the chitinase inhibitory activity of allosamidin.
Archives of insect biochemistry and physiology 1997;36(3):223-7.
1997: C Elke; Martin Vögtli; P Rauch; Margarethe Spindler-Barth; Markus Lezzi
Expression of EcR and USP in Escherichia coli: purification and functional studies.
Archives of insect biochemistry and physiology 1997;35(1-2):59-69.
1996: S Wegener; Margarethe Spindler-Barth; Klaus-Dieter Spindler
A muscarinic acetylcholine receptor, present in the epithelial cell line from Chironomus tentans.
Biological chemistry 1996;377(12):819-24.
1992: Klaus-Dieter Spindler; Margarethe Spindler-Barth; A Turberg; G Adam
Action of brassinosteroids on the epithelial cell line from Chironomus tentans.
Zeitschrift für Naturforschung. C, Journal of biosciences 1992;47(3-4):280-4.
1992: Margarethe Spindler-Barth
Endocrine strategies for the control of ectoparasites and insect pests.
Parasitology research 1992;78(2):89-95.
1991: Margarethe Spindler-Barth; A Turberg; Klaus-Dieter Spindler
On the action of RH 5849, a nonsteroidal ecdysteroid agonist, on a cell line from Chironomus tentans.
Archives of insect biochemistry and physiology 1991;16(1):11-8.
1990: Klaus-Dieter Spindler; Margarethe Spindler-Barth; M Londershausen
Chitin metabolism: a target for drugs against parasites.
Parasitology research 1990;76(4):283-8.
1987: Klaus-Dieter Spindler; Alain Van Wormhoudt; Daniel Sellos; Margarethe Spindler-Barth
Ecdysteroid levels during embryogenesis in the shrimp, Palaemon serratus (Crustacea Decapoda): quantitative and qualitative changes.
General and comparative endocrinology 1987;66(1):116-22.
1986: H Mehlhorn; Klaus-Dieter Spindler; Margarethe Spindler-Barth; V Walldorf; P Andrews; H Thomas
The effect of precocene II and 20-OH-ecdysone on Litomosoides carinii and Dipetalonema viteae in vivo.
Zeitschrift für Parasitenkunde (Berlin, Germany) 1986;72(6):843-5.
1986: Klaus-Dieter Spindler; Margarethe Spindler-Barth; H Mehlhorn
Effects of the juvenile hormone antagonist precocene II and the moulting hormone 20-OH-ecdysone on Litomosoides carinii and Dipetalonema viteae in vitro.
Zeitschrift für Parasitenkunde (Berlin, Germany) 1986;72(6):837-41.