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Paolo Sportoletti

Research Profile

Anatomy

Chemicals & Drugs

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Mouse

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T-Lymphocyte Subsets

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Paolo Sportoletti; Enrico Tiacci; Emanuela Varasano; Pamela Zanghì; Oxana Bereshchenko; Niccolò Bolli; Debora Cecchini; Franca Falzetti; Ilaria Gionfriddo; Tamara Intermesoli; Massimo F Martelli; Maria Paola Martelli; Arianna Masciulli; Roberta Rossi; Brunangelo Falini
The human NPM1 mutation A perturbs megakaryopoiesis in a conditional mouse model.
Maria Paola Martelli; Paolo Sportoletti; Enrico Tiacci; Massimo F Martelli; Brunangelo Falini
Mutational landscape of AML with normal cytogenetics: biological and clinical implications.
Beatrice Del Papa; Stefano Baldoni; Chiara Balucani; Debora Cecchini; Franca Falzetti; Katia Fettucciari; Pierfrancesco Marconi; Massimo F Martelli; Emanuela Rosati; Paolo Sportoletti; Mauro Di Ianni
Notch1 modulates mesenchymal stem cells mediated regulatory T-cell induction.

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All Publications

2013: Paolo Sportoletti; Enrico Tiacci; Emanuela Varasano; Pamela Zanghì; Oxana Bereshchenko; Niccolò Bolli; Debora Cecchini; Franca Falzetti; Ilaria Gionfriddo; Tamara Intermesoli; Massimo F Martelli; Maria Paola Martelli; Arianna Masciulli; Roberta Rossi; Brunangelo Falini
The human NPM1 mutation A perturbs megakaryopoiesis in a conditional mouse model.
Blood 2013;121(17):3447-58.
2013: Maria Paola Martelli; Paolo Sportoletti; Enrico Tiacci; Massimo F Martelli; Brunangelo Falini
Mutational landscape of AML with normal cytogenetics: biological and clinical implications.
Blood reviews 2013;27(1):13-22.
2013: Beatrice Del Papa; Stefano Baldoni; Chiara Balucani; Debora Cecchini; Franca Falzetti; Katia Fettucciari; Pierfrancesco Marconi; Massimo F Martelli; Emanuela Rosati; Paolo Sportoletti; Mauro Di Ianni
Notch1 modulates mesenchymal stem cells mediated regulatory T-cell induction.
European journal of immunology 2013;43(1):182-7.
2012: Mauro Di Ianni; Brunangelo Falini; Stefano Baldoni; Maria Grazia Cantelmi; Alessandra Carotti; Laura Cavalli; Debora Cecchini; Beatrice Del Papa; Roberta Iacucci Ostini; Massimo F Martelli; Antonio Pierini; Paolo Sportoletti; Tiziana Zei; Franca Falzetti
T regulatory cell separation for clinical application.
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 2012;47(2):213-6.
2012: Arati Khanna-Gupta; Michelle Levine; Navid Nia; Pier Paolo Pandolfi; Paolo Sportoletti; Hong Sun; Maria Virgilio; Nirmalee Abayasekara; Stephanie Halene; Jee-Yeong Jeong; Nancy Berliner
Up-regulation of translation eukaryotic initiation factor 4E in nucleophosmin 1 haploinsufficient cells results in changes in CCAAT enhancer-binding protein α activity: implications in myelodysplastic syndrome and acute myeloid leukemia.
The Journal of biological chemistry 2012;287(39):32728-37.
2011: Mauro Di Ianni; Brunangelo Falini; Franca Falzetti; Pierfrancesco Marconi; Katia Perruccio; Yair Reisner; Emanuela Rosati; Loredana Ruggeri; Paolo Sportoletti; Adelmo Terenzi; Andrea Velardi; Franco Aversa; Alessandra Carotti; Beatrice Del Papa; Massimo F Martelli
Immunoselection and clinical use of T regulatory cells in HLA-haploidentical stem cell transplantation.
Best practice & research. Clinical haematology 2011;24(3):459-66.
2011: Rodolfo Bianchini; Onelia Bistoni; Elena Bartoloni Bocci; Roberto Gerli; Giuseppe Nocentini; Maria Grazia Petrillo; Simona Ronchetti; Paolo Sportoletti; Alessia Alunno; Carlo Riccardi
CD4(+) CD25(low) GITR(+) cells: a novel human CD4(+) T-cell population with regulatory activity.
European journal of immunology 2011;41(8):2269-78.
2011: Paolo Sportoletti
How does the NPM1 mutant induce leukemia?
Pediatric reports 2011;3 Suppl 2():e6.
2011: Mauro Di Ianni; Franca Falzetti; Alessandra Carotti; Adelmo Terenzi; Flora Castellino; Elisabetta Bonifacio; Beatrice Del Papa; Tiziana Zei; Roberta Iacucci Ostini; Debora Cecchini; Teresa Aloisi; Katia Perruccio; Loredana Ruggeri; Chiara Balucani; Antonio Pierini; Paolo Sportoletti; Cynthia Aristei; Brunangelo Falini; Yair Reisner; Andrea Velardi; Franco Aversa; Massimo F Martelli
Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation.
Blood 2011;117(14):3921-8.
2011: Simona Ronchetti; Giuseppe Nocentini; Maria Grazia Petrillo; Rodolfo Bianchini; Paolo Sportoletti; Alessandra Bastianelli; Emira M Ayroldi; Carlo Riccardi
Glucocorticoid-Induced TNFR family Related gene (GITR) enhances dendritic cell activity.
Immunology letters 2011;135(1-2):24-33.
2011: M Galuppo; Giuseppe Nocentini; Emanuela Mazzon; Simona Ronchetti; Emanuela Esposito; Luisa Riccardi; Paolo Sportoletti; Rosanna Di Paola; Stefano Bruscoli; Carlo Riccardi; Salvatore Cuzzocrea
The glucocorticoid-induced TNF receptor family-related protein (GITR) is critical to the development of acute pancreatitis in mice.
British journal of pharmacology 2011;162(5):1186-201.
2011: Brunangelo Falini; Maria Paola Martelli; Niccolò Bolli; Paolo Sportoletti; Arcangelo Liso; Enrico Tiacci; Torsten Haferlach
Acute myeloid leukemia with mutated nucleophosmin (NPM1): is it a distinct entity?
Blood 2011;117(4):1109-20.
2009: Brunangelo Falini; Paolo Sportoletti; Maria Paola Martelli
Acute myeloid leukemia with mutated NPM1: diagnosis, prognosis and therapeutic perspectives.
Current opinion in oncology 2009;21(6):573-81.
2008: Paolo Sportoletti; Silvia Grisendi; Samia M Majid; Ke Cheng; John G Clohessy; Agnes Viale; Julie T Feldstein; Pier Paolo Pandolfi
Npm1 is a haploinsufficient suppressor of myeloid and lymphoid malignancies in the mouse.
Blood 2008;111(7):3859-62.
2008: Mauro Di Ianni; Beatrice Del Papa; Maria De Ioanni; Lorenzo Moretti; Elisabetta Bonifacio; Debora Cecchini; Paolo Sportoletti; Franca Falzetti; Antonio Tabilio
Mesenchymal cells recruit and regulate T regulatory cells.
Experimental hematology 2008;36(3):309-18.
2007: Roberto Ria; Anna Maria Scarponi; Franca Falzetti; Stelvio Ballanti; Mauro Di Ianni; Paolo Sportoletti; Michele Cimminiello; Cristiana Gasbarrino; Benedetta Pallone; Angelo Vacca; Franco Dammacco; Elmo Mannarino; Antonio Tabilio
Loss of bone mineral density and secondary hyperparathyroidism are complications of autologous stem cell transplantation.
Leukemia & lymphoma 2007;48(5):923-30.
2006: Paolo Sportoletti; Beatrice Del Papa; Maria De Ioanni; Lorenzo Moretti; Elisabetta Bonifacio; Vania Lanterna; Alain Bell; Katia Fettucciari; Eugenia Carnevali; Tiziana Zei; Franca Falzetti; Massimo F Martelli; Antonio Tabilio; Mauro Di Ianni
Interleukin-7-engineered mesenchymal cells: in vitro effects on naive T-cell population.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2006;12(12):1250-60.
2006: Roberto Ria; Mauro Di Ianni; Paolo Sportoletti; Michele Cimminiello; L Marcomigni; Antonio Tabilio
Recurrent primary plasmacytoma of the eyelid with rapid regional metastasis.
Leukemia & lymphoma 2006;47(3):549-52.
2005: Mauro Di Ianni; Maria De Ioanni; Adelmo Terenzi; Paolo Sportoletti; Lorenzo Moretti; Franca Falzetti; Eugenia Gaozza; Tiziana Zei; Fabrizio Spinozzi; Claude BAGNIS; Patrice Mannoni; Elisabetta Bonifacio; Brunangelo Falini; Massimo F Martelli; Beatrice Del Papa; Antonio Tabilio
Interleukin 7-engineered stromal cells: a new approach for hastening naive T cell recruitment.
Human gene therapy 2005;16(6):752-64.
2004: Mauro Di Ianni; Beatrice Del Papa; Maria De Ioanni; Paolo Sportoletti; Lorenzo Moretti; Franca Falzetti; Massimo F Martelli; Antonio Tabilio
Mesenchymal cells: a vehicle for gene therapy.
Blood cells, molecules & diseases 2004;33(3):267-70.