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Tom Sprong

Research Profile

Living Beings

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Physiology

Complement Activation

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Leukocytes, Mononuclear

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Publications

TOP 3
Stephan P Keijmel; Hans Knoop; Tom Sprong; Jos W M van der Meer; Gijs Bleijenberg; Corine E Delsing; Chantal P Bleeker-Rovers
The Qure study: Q fever fatigue syndrome--response to treatment; a randomized placebo-controlled trial.
Teske Schoffelen; Teun Boekhout; Maria-Teresa Illnait-Zaragozi; Leo A B Joosten; Jacques F Meis; Mihai G Netea; Tom Sprong
Cryptococcus gattii induces a cytokine pattern that is distinct from other cryptococcal species.
L M Kampschreur; M P G Koopmans; Marrigje H Nabuurs-Franssen; D W Notermans; H A Bijlmer; Chantal P Bleeker-Rovers; R A Coutinho; C E Delsing; P M Schneeberger; Tom Sprong; M E E van Kasteren; M C A Wegdam-Blans; Peter C Wever; Jan Jelrik Oosterheert
Defining chronic Q fever: a matter of debate.

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All Publications

2013: Stephan P Keijmel; Hans Knoop; Tom Sprong; Jos W M van der Meer; Gijs Bleijenberg; Corine E Delsing; Chantal P Bleeker-Rovers
The Qure study: Q fever fatigue syndrome--response to treatment; a randomized placebo-controlled trial.
BMC infectious diseases 2013;13():157.
2013: Teske Schoffelen; Teun Boekhout; Maria-Teresa Illnait-Zaragozi; Leo A B Joosten; Jacques F Meis; Mihai G Netea; Tom Sprong
Cryptococcus gattii induces a cytokine pattern that is distinct from other cryptococcal species.
PloS one 2013;8(1):e55579.
2012: L M Kampschreur; M P G Koopmans; Marrigje H Nabuurs-Franssen; D W Notermans; H A Bijlmer; Chantal P Bleeker-Rovers; R A Coutinho; C E Delsing; P M Schneeberger; Tom Sprong; M E E van Kasteren; M C A Wegdam-Blans; Peter C Wever; Jan Jelrik Oosterheert
Defining chronic Q fever: a matter of debate.
The Journal of infection 2012;65(4):362-3.
2012: Linda M Kampschreur; Annemarie M C Koop; Marrigje H Nabuurs-Franssen; Jan Jelrik Oosterheert; Marjolijn J H Pronk; Nicole H M Renders; Yvonne Soethoudt; Tom Sprong; Marjo E van Kasteren; Marjolijn C A Wegdam-Blans; Sybrandus N Blank; Chantal P Bleeker-Rovers; Monique G L De Jager-Leclercq; Corine E Delsing; Rolf H H Groenwold; Cornelis A R Groot; Andy I M Hoepelman; Peter C Wever
Microbiological challenges in the diagnosis of chronic Q fever.
Clinical and vaccine immunology : CVI 2012;19(5):787-90.
2012: Shih-Chin Cheng; Peter Garred; Bernhard Hube; Leo A B Joosten; Bart Jan Kullberg; Lone Schejbel; Tom Sprong; Jos W M van der Meer; Marcel van Deuren; Mihai G Netea
Complement plays a central role in Candida albicans-induced cytokine production by human PBMCs.
European journal of immunology 2012;42(4):993-1004.
2012: M C A Wegdam-Blans; H A Bijlmer; Chantal P Bleeker-Rovers; C E Delsing; L M Kampschreur; M P G Koopmans; P J Lestrade; M H Nabuurs-Franssen; D W Notermans; Jan Jelrik Oosterheert; N H M Renders; Tom Sprong; M E E van Kasteren
Chronic Q fever: review of the literature and a proposal of new diagnostic criteria.
The Journal of infection 2012;64(3):247-59.
2012: Pascal Renner; Marlies Knaup Reymond; Thierry Roger; Tom Sprong; Fred C G J Sweep; Marcel van Deuren; Helen Betts; Murielle Bochud; Pierre-Yves Bochud; Anne-Laure Chanson; Veronique Erard; Saul N Faust; Elene Haralambous; Michael Levin; Elliot Mermel; Robert C Read; Thierry Calandra
A functional microsatellite of the macrophage migration inhibitory factor gene associated with meningococcal disease.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012;26(2):907-16.
2011: Janet van Kuilenburg; Freek Verheugt; Joe Sexton; Tom Sprong; Waander L van Heerde; Leon Bouwels; Paul Lap; Knut Tore Lappegård; Tom Eirik Mollnes; Izabela Plesiewicz; Gheorghe A Pop
Persisting thrombin activity in elderly patients with atrial fibrillation on oral anticoagulation is decreased by anti-inflammatory therapy with intensive cholesterol-lowering treatment.
Journal of clinical lipidology 2011;5(4):273-80.
2011: Martine J Hollestelle; Ka Wai Lai; Peter J Lenting; Tom Sprong; Marcel van Deuren; Philip G de Groot; Niels Bovenschen
Cleavage of von Willebrand factor by granzyme M destroys its factor VIII binding capacity.
PloS one 2011;6(9):e24216.
2010: Cornelia Hoedemaekers; Marcel van Deuren; Tom Sprong; Peter Pickkers; Tom Eirik Mollnes; Ina Klasen; Johannes van der Hoeven
The complement system is activated in a biphasic pattern after coronary artery bypass grafting.
The Annals of thoracic surgery 2010;89(3):710-6.
2009: Tom Sprong; Johanna van der Ven-Jongekrijg; Chris Neeleman; Jos W M van der Meer; Marcel van Deuren
Influence of innate cytokine production capacity on clinical manifestation and severity of pediatric meningococcal disease.
Critical care medicine 2009;37(10):2812-8.
2009: I M E Desar; Marcel van Deuren; Tom Sprong; J B M J Jansen; F Namavar; Christina M.J.E, Vandenbroucke-Grauls; J W M Van Der Meer
Serum bactericidal activity against Helicobacter pylori in patients with hypogammaglobulinaemia.
Clinical and experimental immunology 2009;156(3):434-9.
2009: Corine E Delsing; Chantal P Bleeker-Rovers; Marrigje Nabuurs-Franssen; Tom Sprong; Andre J A M van der Ven; Bart Jan Kullberg
[Q fever, a potential serious disease].
Nederlands tijdschrift voor geneeskunde 2009;153(14):652-7.
2007: Calin Popa; Shahla Abdollahi-Roodsaz; Leo A B Joosten; Nozomi Takahashi; Tom Sprong; Giovanni Matera; Maria Carla Liberto; Alfredo Foca; Marcel van Deuren; Bart Jan Kullberg; Wim B van den Berg; Jos W M van der Meer; Mihai G Netea
Bartonella quintana lipopolysaccharide is a natural antagonist of Toll-like receptor 4.
Infection and immunity 2007;75(10):4831-7.
2007: Meta Roestenberg; Matthew McCall; Tom Eirik Mollnes; Marcel van Deuren; Tom Sprong; Ina S Klasen; Cornelus C Hermsen; Robert W Sauerwein; Andre J A M van der Ven
Complement activation in experimental human malaria infection.
Transactions of the Royal Society of Tropical Medicine and Hygiene 2007;101(7):643-9.
2007: Tom Sprong; Peter Pickkers; Anneke Geurts-Moespot; Johanna van der Ven-Jongekrijg; Chris Neeleman; Marlies Knaup; Didier Leroy; Thierry Calandra; Jos W M van der Meer; Fred C G J Sweep; Marcel van Deuren
Macrophage migration inhibitory factor (MIF) in meningococcal septic shock and experimental human endotoxemia.
Shock (Augusta, Ga.) 2007;27(5):482-7.
2006: Marcel van Deuren; Tom Sprong
[Diagnostic image (283). A man with a swollen tongue].
Nederlands tijdschrift voor geneeskunde 2006;150(43):2400-1; author reply 2401.
2006: Tom Sprong; Dirk Roos; Corry M R Weemaes; Chris Neeleman; Christel L M Geesing; Tom Eirik Mollnes; Marcel van Deuren
Deficient alternative complement pathway activation due to factor D deficiency by 2 novel mutations in the complement factor D gene in a family with meningococcal infections.
Blood 2006;107(12):4865-70.
2006: Lucas T G J van Eijk; Arjan Nooteboom; Thijs Hendriks; Tom Sprong; Mihai G Netea; Paul Smits; Johannes G van der Hoeven; Peter Pickkers
Plasma obtained during human endotoxemia increases endothelial albumin permeability in vitro.
Shock (Augusta, Ga.) 2006;25(4):358-62.
2005: Peter Pickkers; Tom Sprong; Lucas van Eijk; Hans van der Hoeven; Paul Smits; Marcel van Deuren
Vascular endothelial growth factor is increased during the first 48 hours of human septic shock and correlates with vascular permeability.
Shock (Augusta, Ga.) 2005;24(6):508-12.
2005: Mieke F Roelofs; Leo A B Joosten; Shahla Abdollahi-Roodsaz; Antoine W T van Lieshout; Tom Sprong; F H J van den Hoogen; Wim B van den Berg; Timothy Radstake
The expression of toll-like receptors 3 and 7 in rheumatoid arthritis synovium is increased and costimulation of toll-like receptors 3, 4, and 7/8 results in synergistic cytokine production by dendritic cells.
Arthritis and rheumatism 2005;52(8):2313-22.
2004: Tom Sprong; Dominic L Jack; Nigel J Klein; Malcolm W Turner; Peter van der Ley; Liana Steeghs; Liesbeth Jacobs; Jos W M van der Meer; Marcel van Deuren
Mannose binding lectin enhances IL-1beta and IL-10 induction by non-lipopolysaccharide (LPS) components of Neisseria meningitidis.
Cytokine 2004;28(2):59-66.
2004: Tom Sprong; Anne-Sophie W Møller; Anna Bjerre; Elisabeth Wedege; Peter Kierulf; Jos W M van der Meer; Per Brandtzaeg; Marcel van Deuren; Tom Eirik Mollnes
Complement activation and complement-dependent inflammation by Neisseria meningitidis are independent of lipopolysaccharide.
Infection and immunity 2004;72(6):3344-9.
2004: Tom Sprong; Mihai G Netea; Peter van der Ley; Trees J G Verver-Jansen; Liesbeth E H Jacobs; Anton F H Stalenhoef; Jos W M van der Meer; Marcel van Deuren
Human lipoproteins have divergent neutralizing effects on E. coli LPS, N. meningitidis LPS, and complete Gram-negative bacteria.
Journal of lipid research 2004;45(4):742-9.
2003: Tom Sprong; Per Brandtzaeg; Michael Fung; Anne Pharo; E Arne Høiby; Terje E Michaelsen; Audun Aase; Jos W M van der Meer; Marcel van Deuren; Tom Eirik Mollnes
Inhibition of C5a-induced inflammation with preserved C5b-9-mediated bactericidal activity in a human whole blood model of meningococcal sepsis.
Blood 2003;102(10):3702-10.
2002: Tom Sprong; Peter van der Ley; Liana Steeghs; Will J Taw; Trees J W Verver-Janssen; Mihai G Netea; Jos W M van der Meer; Marcel van Deuren
Neisseria meningitidis can induce pro-inflammatory cytokine production via pathways independent from CD14 and toll-like receptor 4.
European cytokine network 2002;13(4):411-7.
2001: Mihai G Netea; Bart Jan Kullberg; Leo A B Joosten; Tom Sprong; Ineke Verschueren; Otto Boerman; F Amiot; Wim B van den Berg; Jos W M van der Meer
Lethal Escherichia coli and Salmonella typhimurium endotoxemia is mediated through different pathways.
European journal of immunology 2001;31(9):2529-38.
2001: Tom Sprong; Nike M M L Stikkelbroeck; Peter van der Ley; Liana Steeghs; Loek van Alphen; Nigel Klein; Mihai G Netea; Jos W M van der Meer; Marcel van Deuren
Contributions of Neisseria meningitidis LPS and non-LPS to proinflammatory cytokine response.
Journal of leukocyte biology 2001;70(2):283-8.