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Vilhelm Bohr

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
32
Brosh, Robert
28
de Souza-Pinto, Nadja
25
Stevnsner, Tinna
21
von Kobbe, Cayetano
21
Opresko, Patricia
18
Dianov, Grigory
17
Cheng, Wen-Hsing
16
Harrigan, Jeanine
14
Orren, David
14
May, Alfred
13
Wilson, David Michael
12
Balajee, Adayabalam
11
Hickson, Ian
11
Karmakar, Parimal
11
Muftuoglu, Meltem

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Publications

TOP 3
Weissman Lior; de Souza-Pinto Nadja C; Mattson Mark P; Bohr Vilhelm A
DNA base excision repair activities in mouse models of Alzheimer's disease.
Ghosh Avik; Rossi Marie L; Aulds Jason; Croteau Deborah; Bohr Vilhelm A
Telomeric D-loops containing 8-oxo-2'-deoxyguanosine are preferred substrates for Werner and Bloom syndrome helicases and are bound by POT1.
Schurman Shepherd H; Hedayati Mohammad; Wang ZhengMing; Singh Dharmendra K; Speina Elzbieta; Zhang Yongqing; Becker Kevin; Macris Margaret; Sung Patrick; Wilson David M; Croteau Deborah L; Bohr Vilhelm A
Direct and indirect roles of RECQL4 in modulating base excision repair capacity.

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All Publications

2009: Weissman Lior; de Souza-Pinto Nadja C; Mattson Mark P; Bohr Vilhelm A
DNA base excision repair activities in mouse models of Alzheimer's disease.
Neurobiology of aging 2009;30(12):2080-1.
2009: Ghosh Avik; Rossi Marie L; Aulds Jason; Croteau Deborah; Bohr Vilhelm A
Telomeric D-loops containing 8-oxo-2'-deoxyguanosine are preferred substrates for Werner and Bloom syndrome helicases and are bound by POT1.
The Journal of biological chemistry 2009;284(45):31074-84.
2009: Schurman Shepherd H; Hedayati Mohammad; Wang ZhengMing; Singh Dharmendra K; Speina Elzbieta; Zhang Yongqing; Becker Kevin; Macris Margaret; Sung Patrick; Wilson David M; Croteau Deborah L; Bohr Vilhelm A
Direct and indirect roles of RECQL4 in modulating base excision repair capacity.
Human molecular genetics 2009;18(18):3470-83.
2009: Kyng Kasper; Croteau Deborah L; Bohr Vilhelm A
Werner syndrome resembles normal aging.
Cell cycle (Georgetown, Tex.) 2009;8(15):2323.
2009: de Souza-Pinto Nadja C; Maynard Scott; Hashiguchi Kazunari; Hu Jingping; Muftuoglu Meltem; Bohr Vilhelm A
The recombination protein RAD52 cooperates with the excision repair protein OGG1 for the repair of oxidative lesions in mammalian cells.
Molecular and cellular biology 2009;29(16):4441-54.
2009: Soerensen Mette; Gredilla Ricardo; Müller-Ohldach Mathis; Werner Alexandra; Bohr Vilhelm A; Osiewacz Heinz D; Stevnsner Tinna
A potential impact of DNA repair on ageing and lifespan in the ageing model organism Podospora anserina: decrease in mitochondrial DNA repair activity during ageing.
Mechanisms of ageing and development 2009;130(8):487-96.
2009: Maddukuri Leena; Speina Elzbieta; Christiansen Mette; Dudzinska Dominika; Zaim Jolanta; Obtulowicz Tomasz; Kabaczyk Sylwia; Komisarski Marek; Bukowy Zuzanna; Szczegielniak Jadwiga; Wójcik Andrzej; Kusmierek Jaroslaw T; Stevnsner Tinna; Bohr Vilhelm A; Tudek Barbara
Cockayne syndrome group B protein is engaged in processing of DNA adducts of lipid peroxidation product trans-4-hydroxy-2-nonenal.
Mutation research 2009;666(1-2):23-31.
2009: de Souza-Pinto Nadja C; Mason Penelope A; Hashiguchi Kazunari; Weissman Lior; Tian Jingyan; Guay David; Lebel Michel; Stevnsner Tinna V; Rasmussen Lene Juel; Bohr Vilhelm A
Novel DNA mismatch-repair activity involving YB-1 in human mitochondria.
DNA repair 2009;8(6):704-19.
2009: Singh Dharmendra Kumar; Ahn Byungchan; Bohr Vilhelm A
Roles of RECQ helicases in recombination based DNA repair, genomic stability and aging.
Biogerontology 2009;10(3):235-52.
2009: Rasmussen Niels; Hjuler Thomas; Bohr Vilhelm A; Cayé-Thomasen Per
[Is the concept "otogenic meningitis" a misunderstanding?]
Ugeskrift for laeger 2009;171(18):1480.
2009: Muftuoglu Meltem; de Souza-Pinto Nadja C; Dogan Arin; Aamann Maria; Stevnsner Tinna; Rybanska Ivana; Kirkali Güldal; Dizdaroglu Miral; Bohr Vilhelm A
Cockayne syndrome group B protein stimulates repair of formamidopyrimidines by NEIL1 DNA glycosylase.
The Journal of biological chemistry 2009;284(14):9270-9.
2009: Kirkali Güldal; de Souza-Pinto Nadja C; Jaruga Pawel; Bohr Vilhelm A; Dizdaroglu Miral
Accumulation of (5'S)-8,5'-cyclo-2'-deoxyadenosine in organs of Cockayne syndrome complementation group B gene knockout mice.
DNA repair 2009;8(2):274-8.
2009: Maynard Scott; Schurman Shepherd H; Harboe Charlotte; de Souza-Pinto Nadja C; Bohr Vilhelm A
Base excision repair of oxidative DNA damage and association with cancer and aging.
Carcinogenesis 2009;30(1):2-10.
2009: Ahn Byungchan; Lee Jae Wan; Jung Hana; Beck Gad; Bohr Vilhelm A
Mechanism of Werner DNA helicase: POT1 and RPA stimulates WRN to unwind beyond gaps in the translocating strand.
PloS one 2009;4(3):e4673.
2008: Bohr Vilhelm A
Rising from the RecQ-age: the role of human RecQ helicases in genome maintenance.
Trends in biochemical sciences 2008;33(12):609-20.
2008: Christmann Markus; Tomicic Maja T; Gestrich Christopher; Roos Wynand P; Bohr Vilhelm A; Kaina Bernd
WRN protects against topo I but not topo II inhibitors by preventing DNA break formation.
DNA repair 2008;7(12):1999-2009.
2008: Fried Linda P; Varadhan Ravi; Bohr Vilhelm A
Opinion section on frailty.
Mechanisms of ageing and development 2008;129(11):665.
2008: Muftuoglu Meltem; Oshima Junko; von Kobbe Cayetano; Cheng Wen-Hsing; Leistritz Dru F; Bohr Vilhelm A
The clinical characteristics of Werner syndrome: molecular and biochemical diagnosis.
Human genetics 2008;124(4):369-77.
2008: Aune Gregory J; Takagi Kazutaka; Sordet Olivier; Guirouilh-Barbat Josée; Antony Smitha; Bohr Vilhelm A; Pommier Yves
Von Hippel-Lindau-coupled and transcription-coupled nucleotide excision repair-dependent degradation of RNA polymerase II in response to trabectedin.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(20):6449-55.
2008: Sander Miriam; Avlund Kirsten; Lauritzen Martin; Gottlieb Tina; Halliwell Barry; Stevnsner Tinna; Wewer Ulla; Bohr Vilhelm A
Aging-from molecules to populations.
Mechanisms of ageing and development 2008;129(10):614-23.
2008: Muftuoglu Meltem; Kulikowicz Tomasz; Beck Gad; Lee Jae Wan; Piotrowski Jason; Bohr Vilhelm A
Intrinsic ssDNA annealing activity in the C-terminal region of WRN.
Biochemistry 2008;47(39):10247-54.
2008: Bukowy Zuzanna; Harrigan Jeanine A; Ramsden Dale A; Tudek Barbara; Bohr Vilhelm A; Stevnsner Tinna
WRN Exonuclease activity is blocked by specific oxidatively induced base lesions positioned in either DNA strand.
Nucleic acids research 2008;36(15):4975-87.
2008: Cheng Wen-Hsing; Muftic Diana; Muftuoglu Meltem; Dawut Lale; Morris Christa; Helleday Thomas; Shiloh Yosef; Bohr Vilhelm A
WRN is required for ATM activation and the S-phase checkpoint in response to interstrand cross-link-induced DNA double-strand breaks.
Molecular biology of the cell 2008;19(9):3923-33.
2008: Maynard Scott; Swistowska Anna Maria; Lee Jae Wan; Liu Ying; Liu Su-Ting; Da Cruz Alexandre Bettencourt; Rao Mahendra; de Souza-Pinto Nadja C; Zeng Xianmin; Bohr Vilhelm A
Human embryonic stem cells have enhanced repair of multiple forms of DNA damage.
Stem cells (Dayton, Ohio) 2008;26(9):2266-74.
2008: Liu Pingfang; Qian Limin; Sung Jung-Suk; de Souza-Pinto Nadja C; Zheng Li; Bogenhagen Daniel F; Bohr Vilhelm A; Wilson David M; Shen Binghui; Demple Bruce
Removal of oxidative DNA damage via FEN1-dependent long-patch base excision repair in human cell mitochondria.
Molecular and cellular biology 2008;28(16):4975-87.
2008: Kusumoto Rika; Dawut Lala; Marchetti Caterina; Wan Lee Jae; Vindigni Alessandro; Ramsden Dale; Bohr Vilhelm A
Werner protein cooperates with the XRCC4-DNA ligase IV complex in end-processing.
Biochemistry 2008;47(28):7548-56.
2008: Hyun Moonjung; Bohr Vilhelm A; Ahn Byungchan
Biochemical characterization of the WRN-1 RecQ helicase of Caenorhabditis elegans.
Biochemistry 2008;47(28):7583-93.
2008: Stevnsner Tinna; Muftuoglu Meltem; Aamann Maria Diget; Bohr Vilhelm A
The role of Cockayne Syndrome group B (CSB) protein in base excision repair and aging.
Mechanisms of ageing and development 2008;129(7-8):441-8.
2008: de Souza-Pinto Nadja C; Wilson David M; Stevnsner Tinna V; Bohr Vilhelm A
Mitochondrial DNA, base excision repair and neurodegeneration.
DNA repair 2008;7(7):1098-109.
2008: Yang Jenq-Lin; Weissman Lior; Bohr Vilhelm A; Mattson Mark P
Mitochondrial DNA damage and repair in neurodegenerative disorders.
DNA repair 2008;7(7):1110-20.
2008: Wilson David M; Bohr Vilhelm A; McKinnon Peter J
DNA damage, DNA repair, ageing and age-related disease.
Mechanisms of ageing and development 2008;129(7-8):349-52.
2008: Michishita Eriko; McCord Ronald A; Berber Elisabeth; Kioi Mitomu; Padilla-Nash Hesed; Damian Mara; Cheung Peggie; Kusumoto Rika; Kawahara Tiara L A; Barrett J Carl; Chang Howard Y; Bohr Vilhelm A; Ried Thomas; Gozani Or; Chua Katrin F
SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin.
Nature 2008;452(7186):492-6.
2008: Hyun Moonjung; Lee Jihyun; Lee Kyungjin; May Alfred; Bohr Vilhelm A; Ahn Byungchan
Longevity and resistance to stress correlate with DNA repair capacity in Caenorhabditis elegans.
Nucleic acids research 2008;36(4):1380-9.
2008: Liu Yie; Bohr Vilhelm A; Lansdorp Peter
Telomere, telomerase and aging.
Mechanisms of ageing and development 2008;129(1-2):1-2.
2008: Muftuoglu Meltem; Kusumoto Rika; Speina Elzbieta; Beck Gad; Cheng Wen-Hsing; Bohr Vilhelm A
Acetylation regulates WRN catalytic activities and affects base excision DNA repair.
PloS one 2008;3(4):e1918.
2007: Harrigan Jeanine A; Piotrowski Jason; Di Noto Luca; Levine Rodney L; Bohr Vilhelm A
Metal-catalyzed oxidation of the Werner syndrome protein causes loss of catalytic activities and impaired protein-protein interactions.
The Journal of biological chemistry 2007;282(50):36403-11.
2007: Pereira Mandy; Mason Penelope; Szczesny Roman J; Maddukuri Leena; Dziwura Sylwia; Jedrzejczak Robert; Paul Erin; Wojcik Andrzej; Dybczynska Lien; Tudek Barbara; Bartnik Ewa; Klysik Jan; Bohr Vilhelm A; Stepien Piotr P
Interaction of human SUV3 RNA/DNA helicase with BLM helicase; loss of the SUV3 gene results in mouse embryonic lethality.
Mechanisms of ageing and development 2007;128(11-12):609-17.
2007: Yang Hongying; Yang Tianle; Baur Joseph A; Perez Evelyn; Matsui Takashi; Carmona Juan J; Lamming Dudley W; Souza-Pinto Nadja C; Bohr Vilhelm A; Rosenzweig Anthony; de Cabo Rafael; Sauve Anthony A; Sinclair David A
Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival.
Cell 2007;130(6):1095-107.
2007: Das Aditi; Boldogh Istvan; Lee Jae Wan; Harrigan Jeanine A; Hegde Muralidhar L; Piotrowski Jason; de Souza Pinto Nadja; Ramos William; Greenberg Marc M; Hazra Tapas K; Mitra Sankar; Bohr Vilhelm A
The human Werner syndrome protein stimulates repair of oxidative DNA base damage by the DNA glycosylase NEIL1.
The Journal of biological chemistry 2007;282(36):26591-602.
2007: Cheng Wen-Hsing; Muftuoglu Meltem; Bohr Vilhelm A
Werner syndrome protein: functions in the response to DNA damage and replication stress in S-phase.
Experimental gerontology 2007;42(9):871-8.
2007: Jiao R; Harrigan J A; Shevelev I; Dietschy T; Selak N; Indig F E; Piotrowski J; Janscak P; Bohr V A; Stagljar I
The Werner syndrome protein is required for recruitment of chromatin assembly factor 1 following DNA damage.
Oncogene 2007;26(26):3811-22.
2007: Bohr V A; Ottersen O P; Tønjum T
Genome instability and DNA repair in brain, ageing and neurological disease.
Neuroscience 2007;145(4):1183-6.
2007: Alrefai Rudaina H; Winter David B; Bohr Vilhelm A; Gearhart Patricia J
Nucleotide excision repair in an immunoglobulin variable gene is less efficient than in a housekeeping gene.
Molecular immunology 2007;44(11):2800-5.
2007: Wilson David M; Bohr Vilhelm A
The mechanics of base excision repair, and its relationship to aging and disease.
DNA repair 2007;6(4):544-59.
2007: Weissman L; de Souza-Pinto N C; Stevnsner T; Bohr V A
DNA repair, mitochondria, and neurodegeneration.
Neuroscience 2007;145(4):1318-29.
2007: Harrigan Jeanine A; Fan Jinshui; Momand Jamil; Perrino Fred W; Bohr Vilhelm A; Wilson David M
WRN exonuclease activity is blocked by DNA termini harboring 3' obstructive groups.
Mechanisms of ageing and development 2007;128(3):259-66.
2007: Kraemer Kenneth H; Sander Miriam; Bohr Vilhelm A
New areas of focus at workshop on human diseases involving DNA repair deficiency and premature aging.
Mechanisms of ageing and development 2007;128(2):229-35.
2007: Kusumoto Rika; Muftuoglu Meltem; Bohr Vilhelm A
The role of WRN in DNA repair is affected by post-translational modifications.
Mechanisms of ageing and development 2007;128(1):50-7.
2007: Brosh Robert M; Bohr Vilhelm A
Human premature aging, DNA repair and RecQ helicases.
Nucleic acids research 2007;35(22):7527-44.
2007: Weissman Lior; Jo Dong-Gyu; Sørensen Martin M; de Souza-Pinto Nadja C; Markesbery William R; Mattson Mark P; Bohr Vilhelm A
Defective DNA base excision repair in brain from individuals with Alzheimer's disease and amnestic mild cognitive impairment.
Nucleic acids research 2007;35(16):5545-55.
2007: Imam Syed Z; Indig Fred E; Cheng Wen-Hsing; Saxena Satya P; Stevnsner Tinna; Kufe Donald; Bohr Vilhelm A
Cockayne syndrome protein B interacts with and is phosphorylated by c-Abl tyrosine kinase.
Nucleic acids research 2007;35(15):4941-51.
2007: Wong Heng-Kuan; Muftuoglu Meltem; Beck Gad; Imam Syed Z; Bohr Vilhelm A; Wilson David M
Cockayne syndrome B protein stimulates apurinic endonuclease 1 activity and protects against agents that introduce base excision repair intermediates.
Nucleic acids research 2007;35(12):4103-13.
2006: Otterlei Marit; Bruheim Per; Ahn Byungchan; Bussen Wendy; Karmakar Parimal; Baynton Kathy; Bohr Vilhelm A
Werner syndrome protein participates in a complex with RAD51, RAD54, RAD54B and ATR in response to ICL-induced replication arrest.
Journal of cell science 2006;119(Pt 24):5137-46.
2006: Eller Mark S; Liao Xiaodong; Liu SuiYang; Hanna Kendra; Bäckvall Helena; Opresko Patricia L; Bohr Vilhelm A; Gilchrest Barbara A
A role for WRN in telomere-based DNA damage responses.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(41):15073-8.
2006: Deeg H Joachim; Friedman Debra; Bohr Vilhelm A; Constine Louis; Jones Irene M; Sigurdson Alice; Socié Gérard; Van Zant Gary; Wei Qingyi; Martin Paul
Transplantation and aging.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2006;12(9):893-8.
2006: Imam Syed Z; Karahalil Bensu; Hogue Barbara A; Souza-Pinto Nadja C; Bohr Vilhelm A
Mitochondrial and nuclear DNA-repair capacity of various brain regions in mouse is altered in an age-dependent manner.
Neurobiology of aging 2006;27(8):1129-36.
2006: Rasmussen Lene Juel; Stevnsner Tinna; Bohr Vilhelm A
[DNA repair--a fundamental factor in ageing and development of cancer]
Ugeskrift for laeger 2006;168(24):2332-5.
2006: Agrelo Ruben; Cheng Wen-Hsing; Setien Fernando; Ropero Santiago; Espada Jesus; Fraga Mario F; Herranz Michel; Paz Maria F; Sanchez-Cespedes Montserrat; Artiga Maria Jesus; Guerrero David; Castells Antoni; von Kobbe Cayetano; Bohr Vilhelm A; Esteller Manel
Epigenetic inactivation of the premature aging Werner syndrome gene in human cancer.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(23):8822-7.
2006: Hisama Fuki M; Bohr Vilhelm A; Oshima Junko
WRN's tenth anniversary.
Science of aging knowledge environment : SAGE KE 2006;2006(10):pe18.
2006: Lukas Jiri; Bohr Vilhelm A; Halazonetis Thanos D
Cellular responses to DNA damage: current state of the field and review of the 52nd Benzon Symposium.
DNA repair 2006;5(5):591-601.
2006: Zhang Peisu; Furukawa Katsutoshi; Opresko Patricia L; Xu Xiangru; Bohr Vilhelm A; Mattson Mark P
TRF2 dysfunction elicits DNA damage responses associated with senescence in proliferating neural cells and differentiation of neurons.
Journal of neurochemistry 2006;97(2):567-81.
2006: Bischoff Claus; Petersen Hans Christian; Graakjaer Jesper; Andersen-Ranberg Karen; Vaupel James W; Bohr Vilhelm A; Kølvraa Steen; Christensen Kaare
No association between telomere length and survival among the elderly and oldest old.
Epidemiology (Cambridge, Mass.) 2006;17(2):190-4.
2006: Spillare E A; Wang X W; von Kobbe C; Bohr V A; Hickson I D; Harris C C
Redundancy of DNA helicases in p53-mediated apoptosis.
Oncogene 2006;25(14):2119-23.
2006: Muftuoglu Meltem; Wong Heng Kuan; Imam Syed Z; Wilson David M; Bohr Vilhelm A; Opresko Patricia L
Telomere repeat binding factor 2 interacts with base excision repair proteins and stimulates DNA synthesis by DNA polymerase beta.
Cancer research 2006;66(1):113-24.
2006: Brosh Robert M; Opresko Patricia L; Bohr Vilhelm A
Enzymatic mechanism of the WRN helicase/nuclease.
Methods in enzymology 2006;409():52-85.
2006: Cheng Wen-Hsing; Kusumoto Rika; Opresko Patricia L; Sui XiuFen; Huang Shurong; Nicolette Matthew L; Paull Tanya T; Campisi Judith; Seidman Michael; Bohr Vilhelm A
Collaboration of Werner syndrome protein and BRCA1 in cellular responses to DNA interstrand cross-links.
Nucleic acids research 2006;34(9):2751-60.
2006: Anson R Michael; Mason Penelope A; Bohr Vilhelm A
Gene-specific and mitochondrial repair of oxidative DNA damage.
Methods in molecular biology (Clifton, N.J.) 2006;314():155-81.
2006: Harrigan Jeanine A; Wilson David M; Prasad Rajendra; Opresko Patricia L; Beck Gad; May Alfred; Wilson Samuel H; Bohr Vilhelm A
The Werner syndrome protein operates in base excision repair and cooperates with DNA polymerase beta.
Nucleic acids research 2006;34(2):745-54.
2006: Muftuoglu Meltem; Sharma Sudha; Thorslund Tina; Stevnsner Tinna; Soerensen Martin M; Brosh Robert M; Bohr Vilhelm A
Cockayne syndrome group B protein has novel strand annealing and exchange activities.
Nucleic acids research 2006;34(1):295-304.
2005: Hu Jingping; de Souza-Pinto Nadja C; Haraguchi Kazuhiro; Hogue Barbara A; Jaruga Pawel; Greenberg Marc M; Dizdaroglu Miral; Bohr Vilhelm A
Repair of formamidopyrimidines in DNA involves different glycosylases: role of the OGG1, NTH1, and NEIL1 enzymes.
The Journal of biological chemistry 2005;280(49):40544-51.
2005: Kyng Kasper J; Bohr Vilhelm A
Gene expression and DNA repair in progeroid syndromes and human aging.
Ageing research reviews 2005;4(4):579-602.
2005: Lee Jae Wan; Kusumoto Rika; Doherty Kevin M; Lin Guang-Xin; Zeng Wangyong; Cheng Wen-Hsing; von Kobbe Cayetano; Brosh Robert M; Hu Jin-Shan; Bohr Vilhelm A
Modulation of Werner syndrome protein function by a single mutation in the conserved RecQ domain.
The Journal of biological chemistry 2005;280(47):39627-36.
2005: Karmakar Parimal; Bohr Vilhelm A
Cellular dynamics and modulation of WRN protein is DNA damage specific.
Mechanisms of ageing and development 2005;126(11):1146-58.
2005: Bischoff Claus; Graakjaer Jesper; Petersen Hans Christian; Jeune Bernard; Bohr Vilhelm A; Koelvraa Steen; Christensen Kaare
Telomere length among the elderly and oldest-old.
Twin research and human genetics : the official journal of the International Society for Twin Studies 2005;8(5):425-32.
2005: Christiansen Mette; Thorslund Tina; Jochimsen Bjarne; Bohr Vilhelm A; Stevnsner Tinna
The Cockayne syndrome group B protein is a functional dimer.
The FEBS journal 2005;272(17):4306-14.
2005: Thorslund Tina; von Kobbe Cayetano; Harrigan Jeanine A; Indig Fred E; Christiansen Mette; Stevnsner Tinna; Bohr Vilhelm A
Cooperation of the Cockayne syndrome group B protein and poly(ADP-ribose) polymerase 1 in the response to oxidative stress.
Molecular and cellular biology 2005;25(17):7625-36.
2005: Opresko Patricia L; Mason Penelope A; Podell Elaine R; Lei Ming; Hickson Ian D; Cech Thomas R; Bohr Vilhelm A
POT1 stimulates RecQ helicases WRN and BLM to unwind telomeric DNA substrates.
The Journal of biological chemistry 2005;280(37):32069-80.
2005: Bohr Vilhelm A
Deficient DNA repair in the human progeroid disorder, Werner syndrome.
Mutation research 2005;577(1-2):252-9.
2005: Wu Leonard; Chan Kok Lung; Ralf Christine; Bernstein Douglas A; Garcia Patrick L; Bohr Vilhelm A; Vindigni Alessandro; Janscak Pavel; Keck James L; Hickson Ian D
The HRDC domain of BLM is required for the dissolution of double Holliday junctions.
The EMBO journal 2005;24(14):2679-87.
2005: Kyng Kasper J; May Alfred; Stevnsner Tinna; Becker Kevin G; Kølvrå Steen; Bohr Vilhelm A
Gene expression responses to DNA damage are altered in human aging and in Werner Syndrome.
Oncogene 2005;24(32):5026-42.
2005: Mambo Elizabeth; Chatterjee Aditi; de Souza-Pinto Nadja C; Mayard Sabine; Hogue Barbara A; Hoque Mohammad O; Dizdaroglu Miral; Bohr Vilhelm A; Sidransky David
Oxidized guanine lesions and hOgg1 activity in lung cancer.
Oncogene 2005;24(28):4496-508.
2005: Kraemer Kenneth H; Bohr Vilhelm A;
The DNA Repair Interest Group: a global village.
DNA repair 2005;4(4):405-6.
2005: Stuart J A; Bourque B M; de Souza-Pinto N C; Bohr V A
No evidence of mitochondrial respiratory dysfunction in OGG1-null mice deficient in removal of 8-oxodeoxyguanine from mitochondrial DNA.
Free radical biology & medicine 2005;38(6):737-45.
2005: Cheng Wen-Hsing; Sakamoto Shuichi; Fox Jennifer T; Komatsu Kenshi; Carney James; Bohr Vilhelm A
Werner syndrome protein associates with gamma H2AX in a manner that depends upon Nbs1.
FEBS letters 2005;579(6):1350-6.
2005: Bohr Vilhelm A; Sander Miriam; Kraemer Kenneth H
Rare diseases provide rare insights into DNA repair pathways, TFIIH, aging and cancer center.
DNA repair 2005;4(2):293-302.
2005: Lee Jae Wan; Harrigan Jeanine; Opresko Patricia L; Bohr Vilhelm A
Pathways and functions of the Werner syndrome protein.
Mechanisms of ageing and development 2005;126(1):79-86.
2005: Stuart J A; Mayard S; Hashiguchi K; Souza-Pinto N C; Bohr V A
Localization of mitochondrial DNA base excision repair to an inner membrane-associated particulate fraction.
Nucleic acids research 2005;33(12):3722-32.
2005: Hu Jingping; Imam Syed Z; Hashiguchi Kazunari; de Souza-Pinto Nadja C; Bohr Vilhelm A
Phosphorylation of human oxoguanine DNA glycosylase (alpha-OGG1) modulates its function.
Nucleic acids research 2005;33(10):3271-82.
2005: Opresko Patricia L; Fan Jinshui; Danzy Shamika; Wilson David M; Bohr Vilhelm A
Oxidative damage in telomeric DNA disrupts recognition by TRF1 and TRF2.
Nucleic acids research 2005;33(4):1230-9.
2004: Von Kobbe Cayetano; May Alfred; Grandori Carla; Bohr Vilhelm A
Werner syndrome cells escape hydrogen peroxide-induced cell proliferation arrest.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(15):1970-2.
2004: Ahn Byungchan; Harrigan Jeanine A; Indig Fred E; Wilson David M; Bohr Vilhelm A
Regulation of WRN helicase activity in human base excision repair.
The Journal of biological chemistry 2004;279(51):53465-74.
2004: de Souza-Pinto Nadja C; Harris Curtis C; Bohr Vilhelm A
p53 functions in the incorporation step in DNA base excision repair in mouse liver mitochondria.
Oncogene 2004;23(39):6559-68.
2004: Hashiguchi Kazunari; Bohr Vilhelm A; de Souza-Pinto Nadja C
Oxidative stress and mitochondrial DNA repair: implications for NRTIs induced DNA damage.
Mitochondrion 2004;4(2-3):215-22.
2004: Bohr Vilhelm A; Metter E Jeffery; Harrigan Jeanine A; von Kobbe Cayetano; Liu Ji Lan; Gray Matthew D; Majumdar Alokes; Wilson David M; Seidman Michael M
Werner syndrome protein 1367 variants and disposition towards coronary artery disease in Caucasian patients.
Mechanisms of ageing and development 2004;125(7):491-6.
2004: Bendixen Mette H; Nexø Bjørn A; Bohr Vilhelm A; Frederiksen Henrik; McGue Matt; Kølvraa Steen; Christensen Kaare
A polymorphic marker in the first intron of the Werner gene associates with cognitive function in aged Danish twins.
Experimental gerontology 2004;39(7):1101-7.
2004: Bohr Vilhelm A; Souza-Pinto Nadja; Wilson Samuel
First US-EU DNA repair meeting: endogenous stress, National Conference Center, VA, USA, 14-18 October 2003.
DNA repair 2004;3(5):543-59.
2004: Cheng Wen-Hsing; von Kobbe Cayetano; Opresko Patricia L; Arthur L Matthew; Komatsu Kenshi; Seidman Michael M; Carney James P; Bohr Vilhelm A
Linkage between Werner syndrome protein and the Mre11 complex via Nbs1.
The Journal of biological chemistry 2004;279(20):21169-76.
2004: Indig Fred Eliezer; Partridge Juneth Joaquin; von Kobbe Cayetano; Aladjem Mirit I; Latterich Martin; Bohr Vilhelm A
Werner syndrome protein directly binds to the AAA ATPase p97/VCP in an ATP-dependent fashion.
Journal of structural biology 2004;146(1-2):251-9.
2004: Opresko Patricia L; Cheng Wen-Hsing; Bohr Vilhelm A
Junction of RecQ helicase biochemistry and human disease.
The Journal of biological chemistry 2004;279(18):18099-102.
2004: Stuart J A; Karahalil B; Hogue B A; Souza-Pinto N C; Bohr V A
Mitochondrial and nuclear DNA base excision repair are affected differently by caloric restriction.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(3):595-7.
2004: Sharma Sudha; Sommers Joshua A; Wu Leonard; Bohr Vilhelm A; Hickson Ian D; Brosh Robert M
Stimulation of flap endonuclease-1 by the Bloom's syndrome protein.
The Journal of biological chemistry 2004;279(11):9847-56.
2004: Hashiguchi K; Stuart J A; de Souza-Pinto N C; Bohr V A
The C-terminal alphaO helix of human Ogg1 is essential for 8-oxoguanine DNA glycosylase activity: the mitochondrial beta-Ogg1 lacks this domain and does not have glycosylase activity.
Nucleic acids research 2004;32(18):5596-608.
2004: von Kobbe Cayetano; Harrigan Jeanine A; Schreiber Valérie; Stiegler Patrick; Piotrowski Jason; Dawut Lale; Bohr Vilhelm A
Poly(ADP-ribose) polymerase 1 regulates both the exonuclease and helicase activities of the Werner syndrome protein.
Nucleic acids research 2004;32(13):4003-14.
2004: Stuart J A; Hashiguchi K; Wilson D M; Copeland W C; Souza-Pinto N C; Bohr V A
DNA base excision repair activities and pathway function in mitochondrial and cellular lysates from cells lacking mitochondrial DNA.
Nucleic acids research 2004;32(7):2181-92.
2003: Bohr Vilhelm A
Werner syndrome and its protein: clinical, cellular and molecular advances.
Mechanisms of ageing and development 2003;124(10-12):1073-82.
2003: Licht Cecilie Löe; Stevnsner Tinna; Bohr Vilhelm A
Cockayne syndrome group B cellular and biochemical functions.
American journal of human genetics 2003;73(6):1217-39.
2003: von Kobbe Cayetano; Harrigan Jeanine A; May Alfred; Opresko Patricia L; Dawut Lale; Cheng Wen-Hsing; Bohr Vilhelm A
Central role for the Werner syndrome protein/poly(ADP-ribose) polymerase 1 complex in the poly(ADP-ribosyl)ation pathway after DNA damage.
Molecular and cellular biology 2003;23(23):8601-13.
2003: von Kobbe Cayetano; Thomä Nicolas H; Czyzewski Bryan K; Pavletich Nikola P; Bohr Vilhelm A
Werner syndrome protein contains three structure-specific DNA binding domains.
The Journal of biological chemistry 2003;278(52):52997-3006.
2003: Harrigan J A; Bohr V A
Human diseases deficient in RecQ helicases.
Biochimie 2003;85(11):1185-93.
2003: Laine Jean-Philippe; Opresko Patricia L; Indig Fred E; Harrigan Jeanine A; von Kobbe Cayetano; Bohr Vilhelm A
Werner protein stimulates topoisomerase I DNA relaxation activity.
Cancer research 2003;63(21):7136-46.
2003: Kyng Kasper J; May Alfred; Kølvraa Steen; Bohr Vilhelm A
Gene expression profiling in Werner syndrome closely resembles that of normal aging.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(21):12259-64.
2003: Cheng Wen-Hsing; von Kobbe Cayetano; Opresko Patricia L; Fields Kesha M; Ren Jian; Kufe Donald; Bohr Vilhelm A
Werner syndrome protein phosphorylation by abl tyrosine kinase regulates its activity and distribution.
Molecular and cellular biology 2003;23(18):6385-95.
2003: Karahalil Bensu; de Souza-Pinto Nadja C; Parsons Jason L; Elder Rhoderick H; Bohr Vilhelm A
Compromised incision of oxidized pyrimidines in liver mitochondria of mice deficient in NTH1 and OGG1 glycosylases.
The Journal of biological chemistry 2003;278(36):33701-7.
2003: Baynton Kathy; Otterlei Marit; Bjørås Magnar; von Kobbe Cayetano; Bohr Vilhelm A; Seeberg Erling
WRN interacts physically and functionally with the recombination mediator protein RAD52.
The Journal of biological chemistry 2003;278(38):36476-86.
2003: Cheng Wen-Hsing; Bohr Vilhelm A
Diverse dealings of the Werner helicase/nuclease.
Science of aging knowledge environment : SAGE KE 2003;2003(31):PE22.
2003: Harrigan Jeanine A; Opresko Patricia L; von Kobbe Cayetano; Kedar Padmini S; Prasad Rajendra; Wilson Samuel H; Bohr Vilhelm A
The Werner syndrome protein stimulates DNA polymerase beta strand displacement synthesis via its helicase activity.
The Journal of biological chemistry 2003;278(25):22686-95.
2003: Opresko Patricia L; Cheng Wen-Hsing; von Kobbe Cayetano; Harrigan Jeanine A; Bohr Vilhelm A
Werner syndrome and the function of the Werner protein; what they can teach us about the molecular aging process.
Carcinogenesis 2003;24(5):791-802.
2003: Graakjaer Jesper; Bischoff Claus; Korsholm Lars; Holstebroe Søren; Vach Werner; Bohr Vilhelm A; Christensen Kaare; Kølvraa Steen
The pattern of chromosome-specific variations in telomere length in humans is determined by inherited, telomere-near factors and is maintained throughout life.
Mechanisms of ageing and development 2003;124(5):629-40.
2003: Jensen Anne; Calvayrac Guillaume; Karahalil Bensu; Bohr Vilhelm A; Stevnsner Tinna
Mammalian 8-oxoguanine DNA glycosylase 1 incises 8-oxoadenine opposite cytosine in nuclei and mitochondria, while a different glycosylase incises 8-oxoadenine opposite guanine in nuclei.
The Journal of biological chemistry 2003;278(21):19541-8.
2003: Tuo Jingsheng; Jaruga Pawel; Rodriguez Henry; Bohr Vilhelm A; Dizdaroglu Miral
Primary fibroblasts of Cockayne syndrome patients are defective in cellular repair of 8-hydroxyguanine and 8-hydroxyadenine resulting from oxidative stress.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(6):668-74.
2003: Kyng Kasper J; May Alfred; Brosh Robert M; Cheng Wen-Hsing; Chen Catheryne; Becker Kevin G; Bohr Vilhelm A
The transcriptional response after oxidative stress is defective in Cockayne syndrome group B cells.
Oncogene 2003;22(8):1135-49.
2003: Christiansen Mette; Stevnsner Tinna; Modin Charlotte; Martensen Pia M; Brosh Robert M; Bohr Vilhelm A
Functional consequences of mutations in the conserved SF2 motifs and post-translational phosphorylation of the CSB protein.
Nucleic acids research 2003;31(3):963-73.
2002: Stevnsner Tinna; Nyaga Simon; de Souza-Pinto Nadja C; van der Horst Gijsbertus T J; Gorgels Theo G M F; Hogue Barbara A; Thorslund Tina; Bohr Vilhelm A
Mitochondrial repair of 8-oxoguanine is deficient in Cockayne syndrome group B.
Oncogene 2002;21(57):8675-82.
2002: Karahalil Bensu; Hogue Barbara A; de Souza-Pinto Nadja C; Bohr Vilhelm A
Base excision repair capacity in mitochondria and nuclei: tissue-specific variations.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(14):1895-902.
2002: Tuo Jingsheng; Chen Catheryne; Zeng Xianmin; Christiansen Mette; Bohr Vilhelm A
Functional crosstalk between hOgg1 and the helicase domain of Cockayne syndrome group B protein.
DNA repair 2002;1(11):913-27.
2002: Stevnsner Tinna; Thorslund Tina; de Souza-Pinto Nadja C; Bohr Vilhelm A
Mitochondrial repair of 8-oxoguanine and changes with aging.
Experimental gerontology 2002;37(10-11):1189-96.
2002: von Kobbe Cayetano; Bohr Vilhelm A
A nucleolar targeting sequence in the Werner syndrome protein resides within residues 949-1092.
Journal of cell science 2002;115(Pt 20):3901-7.
2002: Opresko Patricia L; von Kobbe Cayetano; Laine Jean-Philippe; Harrigan Jeanine; Hickson Ian D; Bohr Vilhelm A
Telomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicases.
The Journal of biological chemistry 2002;277(43):41110-9.
2002: Karmakar Parimal; Snowden Carey M; Ramsden Dale A; Bohr Vilhelm A
Ku heterodimer binds to both ends of the Werner protein and functional interaction occurs at the Werner N-terminus.
Nucleic acids research 2002;30(16):3583-91.
2002: Yang Qin; Zhang Ran; Wang Xin Wei; Spillare Elisa A; Linke Steven P; Subramanian Deepa; Griffith Jack D; Li Ji Liang; Hickson Ian D; Shen Jiang Cheng; Loeb Lawrence A; Mazur Sharlyn J; Appella Ettore; Brosh Robert M; Karmakar Parimal; Bohr Vilhelm A; Harris Curtis C
The processing of Holliday junctions by BLM and WRN helicases is regulated by p53.
The Journal of biological chemistry 2002;277(35):31980-7.
2002: Tuo Jingsheng; Jaruga Pawel; Rodriguez Henry; Dizdaroglu Miral; Bohr Vilhelm A
The cockayne syndrome group B gene product is involved in cellular repair of 8-hydroxyadenine in DNA.
The Journal of biological chemistry 2002;277(34):30832-7.
2002: von Kobbe Cayetano; Karmakar Parimal; Dawut Lale; Opresko Patricia; Zeng Xianmin; Brosh Robert M; Hickson Ian D; Bohr Vilhelm A
Colocalization, physical, and functional interaction between Werner and Bloom syndrome proteins.
The Journal of biological chemistry 2002;277(24):22035-44.
2002: Bohr Vilhelm A
DNA-related pathways defective in human premature aging.
TheScientificWorldJournal 2002;2():1216-26.
2002: Sunesen Morten; Stevnsner Tinna; Brosh Jr Robert M; Dianov Grigory L; Bohr Vilhelm A
Global genome repair of 8-oxoG in hamster cells requires a functional CSB gene product.
Oncogene 2002;21(22):3571-8.
2002: Bohr Vilhelm A
Repair of oxidative DNA damage in nuclear and mitochondrial DNA, and some changes with aging in mammalian cells.
Free radical biology & medicine 2002;32(9):804-12.
2002: Karmakar Parimal; Piotrowski Jason; Brosh Robert M; Sommers Joshua A; Miller Susan P Lees; Cheng Wen-Hsing; Snowden Carey M; Ramsden Dale A; Bohr Vilhelm A
Werner protein is a target of DNA-dependent protein kinase in vivo and in vitro, and its catalytic activities are regulated by phosphorylation.
The Journal of biological chemistry 2002;277(21):18291-302.
2002: Thorslund Tina; Sunesen Morten; Bohr Vilhelm A; Stevnsner Tinna
Repair of 8-oxoG is slower in endogenous nuclear genes than in mitochondrial DNA and is without strand bias.
DNA repair 2002;1(4):261-73.
2002: Bohr Vilhelm A
Human premature aging syndromes and genomic instability.
Mechanisms of ageing and development 2002;123(8):987-93.
2002: Brosh Robert M; Bohr Vilhelm A
Roles of the Werner syndrome protein in pathways required for maintenance of genome stability.
Experimental gerontology 2002;37(4):491-506.
2002: Bohr Vilhelm A; Stevnsner Tinna; de Souza-Pinto Nadja C
Mitochondrial DNA repair of oxidative damage in mammalian cells.
Gene 2002;286(1):127-34.
2002: Mambo Elizabeth; Nyaga Simon G; Bohr Vilhelm A; Evans Michele K
Defective repair of 8-hydroxyguanine in mitochondria of MCF-7 and MDA-MB-468 human breast cancer cell lines.
Cancer research 2002;62(5):1349-55.
2002: Selzer Rebecca R; Nyaga Simon; Tuo Jingsheng; May Alfred; Muftuoglu Meltem; Christiansen Mette; Citterio Elisabetta; Brosh Robert M; Bohr Vilhelm A
Differential requirement for the ATPase domain of the Cockayne syndrome group B gene in the processing of UV-induced DNA damage and 8-oxoguanine lesions in human cells.
Nucleic acids research 2002;30(3):782-93.
2002: Muftuoglu Meltem; Selzer Rebecca; Tuo Jingsheng; Brosh Robert M; Bohr Vilhelm A
Phenotypic consequences of mutations in the conserved motifs of the putative helicase domain of the human Cockayne syndrome group B gene.
Gene 2002;283(1-2):27-40.
2002: de Souza-Pinto Nadja C; Bohr Vilhelm A
The mitochondrial theory of aging: involvement of mitochondrial DNA damage and repair.
International review of neurobiology 2002;53():519-34.
2002: Bohr Vilhelm A; Brosh Robert M; von Kobbe Cayetano; Opresko Patricia; Karmakar Parimal
Pathways defective in the human premature aging disease Werner syndrome.
Biogerontology 2002;3(1-2):89-94.
2002: Nyaga Simon G; Bohr Vilhelm A
Characterization of specialized mtDNA glycosylases.
Methods in molecular biology (Clifton, N.J.) 2002;197():227-44.
2001: Tuo J; Müftüoglu M; Chen C; Jaruga P; Selzer R R; Brosh R M; Rodriguez H; Dizdaroglu M; Bohr V A
The Cockayne Syndrome group B gene product is involved in general genome base excision repair of 8-hydroxyguanine in DNA.
The Journal of biological chemistry 2001;276(49):45772-9.
2001: Opresko P L; Laine J P; Brosh R M; Seidman M M; Bohr V A
Coordinate action of the helicase and 3' to 5' exonuclease of Werner syndrome protein.
The Journal of biological chemistry 2001;276(48):44677-87.
2001: Dianova I I; Bohr V A; Dianov G L
Interaction of human AP endonuclease 1 with flap endonuclease 1 and proliferating cell nuclear antigen involved in long-patch base excision repair.
Biochemistry 2001;40(42):12639-44.
2001: Brosh R M; von Kobbe C; Sommers J A; Karmakar P; Opresko P L; Piotrowski J; Dianova I; Dianov G L; Bohr V A
Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity.
The EMBO journal 2001;20(20):5791-801.
2001: Gabrielson K L; Hogue B A; Bohr V A; Cardounel A J; Nakajima W; Kofler J; Zweier J L; Rodriguez E R; Martin L J; de Souza-Pinto N C; Bressler J
Mitochondrial toxin 3-nitropropionic acid induces cardiac and neurotoxicity differentially in mice.
The American journal of pathology 2001;159(4):1507-20.
2001: Brosh R M; Karmakar P; Sommers J A; Yang Q; Wang X W; Spillare E A; Harris C C; Bohr V A
p53 Modulates the exonuclease activity of Werner syndrome protein.
The Journal of biological chemistry 2001;276(37):35093-102.
2001: Rosner K; Winter D B; Skovgaard G L; Oshima J; Gearhart P J; Bohr V A
Analysis of microsatellite instability and hypermutation of immunoglobulin variable genes in Werner syndrome.
Mechanisms of ageing and development 2001;122(11):1121-33.
2001: de Souza-Pinto N C; Eide L; Hogue B A; Thybo T; Stevnsner T; Seeberg E; Klungland A; Bohr V A
Repair of 8-oxodeoxyguanosine lesions in mitochondrial dna depends on the oxoguanine dna glycosylase (OGG1) gene and 8-oxoguanine accumulates in the mitochondrial dna of OGG1-defective mice.
Cancer research 2001;61(14):5378-81.
2001: Rosner K; Winter D B; Tarone R E; Skovgaard G L; Bohr V A; Gearhart P J
Third complementarity-determining region of mutated VH immunoglobulin genes contains shorter V, D, J, P, and N components than non-mutated genes.
Immunology 2001;103(2):179-87.
2001: Orren D K; Machwe A; Karmakar P; Piotrowski J; Cooper M P; Bohr V A
A functional interaction of Ku with Werner exonuclease facilitates digestion of damaged DNA.
Nucleic acids research 2001;29(9):1926-34.
2001: de Souza-Pinto N C; Hogue B A; Bohr V A
DNA repair and aging in mouse liver: 8-oxodG glycosylase activity increase in mitochondrial but not in nuclear extracts.
Free radical biology & medicine 2001;30(8):916-23.
2001: Rosner K; Winter D B; Kasmer C; Skovgaard G L; Tarone R E; Bohr V A; Gearhart P J
Impact of age on hypermutation of immunoglobulin variable genes in humans.
Journal of clinical immunology 2001;21(2):102-15.
2001: Podlutsky A J; Dianova I I; Podust V N; Bohr V A; Dianov G L
Human DNA polymerase beta initiates DNA synthesis during long-patch repair of reduced AP sites in DNA.
The EMBO journal 2001;20(6):1477-82.
2001: Brosh R M; Majumdar A; Desai S; Hickson I D; Bohr V A; Seidman M M
Unwinding of a DNA triple helix by the Werner and Bloom syndrome helicases.
The Journal of biological chemistry 2001;276(5):3024-30.
2001: Podlutsky A J; Dianova I I; Wilson S H; Bohr V A; Dianov G L
DNA synthesis and dRPase activities of polymerase beta are both essential for single-nucleotide patch base excision repair in mammalian cell extracts.
Biochemistry 2001;40(3):809-13.
2001: Bohr V A; Souza Pinto N; Nyaga S G; Dianov G; Kraemer K; Seidman M M; Brosh R M
DNA repair and mutagenesis in Werner syndrome.
Environmental and molecular mutagenesis 2001;38(2-3):227-34.
2001: Dianov G L; Souza-Pinto N; Nyaga S G; Thybo T; Stevnsner T; Bohr V A
Base excision repair in nuclear and mitochondrial DNA.
Progress in nucleic acid research and molecular biology 2001;68():285-97.
2000: Bohr V A; Cooper M; Orren D; Machwe A; Piotrowski J; Sommers J; Karmakar P; Brosh R
Werner syndrome protein: biochemical properties and functional interactions.
Experimental gerontology 2000;35(6-7):695-702.
2000: Machwe A; Orren D K; Bohr V A
Accelerated methylation of ribosomal RNA genes during the cellular senescence of Werner syndrome fibroblasts.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(12):1715-24.
2000: Sunesen M; Selzer R R; Brosh R M; Balajee A S; Stevnsner T; Bohr V A
Molecular characterization of an acidic region deletion mutant of Cockayne syndrome group B protein.
Nucleic acids research 2000;28(16):3151-9.
2000: Brosh R M; Li J L; Kenny M K; Karow J K; Cooper M P; Kureekattil R P; Hickson I D; Bohr V A
Replication protein A physically interacts with the Bloom's syndrome protein and stimulates its helicase activity.
The Journal of biological chemistry 2000;275(31):23500-8.
2000: Constantinou A; Tarsounas M; Karow J K; Brosh R M; Bohr V A; Hickson I D; West S C
Werner's syndrome protein (WRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest.
EMBO reports 2000;1(1):80-4.
2000: Machwe A; Ganunis R; Bohr V A; Orren D K
Selective blockage of the 3'-->5' exonuclease activity of WRN protein by certain oxidative modifications and bulky lesions in DNA.
Nucleic acids research 2000;28(14):2762-70.
2000: Brosh R M; Karow J K; White E J; Shaw N D; Hickson I D; Bohr V A
Potent inhibition of werner and bloom helicases by DNA minor groove binding drugs.
Nucleic acids research 2000;28(12):2420-30.
2000: Cooper M P; Machwe A; Orren D K; Brosh R M; Ramsden D; Bohr V A
Ku complex interacts with and stimulates the Werner protein.
Genes & development 2000;14(8):907-12.
2000: Dianov G L; Thybo T; Dianova I I; Lipinski L J; Bohr V A
Single nucleotide patch base excision repair is the major pathway for removal of thymine glycol from DNA in human cell extracts.
The Journal of biological chemistry 2000;275(16):11809-13.
2000: Christiansen M; Stevnsner T; Bohr V A; Clark B F; Rattan S I
Gene-specific DNA repair of pyrimidine dimers does not decline during cellular aging in vitro.
Experimental cell research 2000;256(1):308-14.
2000: May A; Bohr V A
Gene-specific repair of gamma-ray-induced DNA strand breaks in colon cancer cells: no coupling to transcription and no removal from the mitochondrial genome.
Biochemical and biophysical research communications 2000;269(2):433-7.
2000: Ravn P; Kjaer S; Jensen K H; Wind T; Jensen K B; Kristensen P; Brosh R M; Orren D K; Bohr V A; Clark B F
Identification of phage antibodies toward the Werner protein by selection on Western blots.
Electrophoresis 2000;21(3):509-16.
2000: Prasad R; Dianov G L; Bohr V A; Wilson S H
FEN1 stimulation of DNA polymerase beta mediates an excision step in mammalian long patch base excision repair.
The Journal of biological chemistry 2000;275(6):4460-6.
2000: Anson R M; Hudson E; Bohr V A
Mitochondrial endogenous oxidative damage has been overestimated.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(2):355-60.
2000: Balajee A S; Proietti De Santis L; Brosh R M; Selzer R; Bohr V A
Role of the ATPase domain of the Cockayne syndrome group B protein in UV induced apoptosis.
Oncogene 2000;19(4):477-89.
1999: Brosh R M; Balajee A S; Selzer R R; Sunesen M; Proietti De Santis L; Bohr V A
The ATPase domain but not the acidic region of Cockayne syndrome group B gene product is essential for DNA repair.
Molecular biology of the cell 1999;10(11):3583-94.
1999: Alrefai R H; Beecham E J; Bohr V A; Gearhart P J
Less repair of pyrimidine dimers and single-strand breaks in genes by scid cells.
Biochemical and biophysical research communications 1999;264(3):878-82.
1999: Balajee A S; Dianova I; Bohr V A
Oxidative damage-induced PCNA complex formation is efficient in xeroderma pigmentosum group A but reduced in Cockayne syndrome group B cells.
Nucleic acids research 1999;27(22):4476-82.
1999: Mazur S J; Sakaguchi K; Appella E; Wang X W; Harris C C; Bohr V A
Preferential binding of tumor suppressor p53 to positively or negatively supercoiled DNA involves the C-terminal domain.
Journal of molecular biology 1999;292(2):241-9.
1999: Stierum R H; Dianov G L; Bohr V A
Single-nucleotide patch base excision repair of uracil in DNA by mitochondrial protein extracts.
Nucleic acids research 1999;27(18):3712-9.
1999: Orren D K; Brosh R M; Nehlin J O; Machwe A; Gray M D; Bohr V A
Enzymatic and DNA binding properties of purified WRN protein: high affinity binding to single-stranded DNA but not to DNA damage induced by 4NQO.
Nucleic acids research 1999;27(17):3557-66.
1999: Bohr V A; Anson R M
Mitochondrial DNA repair pathways.
Journal of bioenergetics and biomembranes 1999;31(4):391-8.
1999: Anson R M; Sentürker S; Dizdaroglu M; Bohr V A
Measurement of oxidatively induced base lesions in liver from Wistar rats of different ages.
Free radical biology & medicine 1999;27(3-4):456-62.
1999: Dianov G L; Jensen B R; Kenny M K; Bohr V A
Replication protein A stimulates proliferating cell nuclear antigen-dependent repair of abasic sites in DNA by human cell extracts.
Biochemistry 1999;38(34):11021-5.
1999: Lipinski L J; Hoehr N; Mazur S J; Dianov G L; Sentürker S; Dizdaroglu M; Bohr V A
Repair of oxidative DNA base lesions induced by fluorescent light is defective in xeroderma pigmentosum group A cells.
Nucleic acids research 1999;27(15):3153-8.
1999: Balajee A S; Machwe A; May A; Gray M D; Oshima J; Martin G M; Nehlin J O; Brosh R; Orren D K; Bohr V A
The Werner syndrome protein is involved in RNA polymerase II transcription.
Molecular biology of the cell 1999;10(8):2655-68.
1999: Croteau D L; Stierum R H; Bohr V A
Mitochondrial DNA repair pathways.
Mutation research 1999;434(3):137-48.
1999: Cooper M P; Balajee A S; Bohr V A
The C-terminal domain of p21 inhibits nucleotide excision repair In vitro and In vivo.
Molecular biology of the cell 1999;10(7):2119-29.
1999: Bohr V A
[Focusing on the molecular biology of aging]
Ugeskrift for laeger 1999;161(25):3819-22.
1999: Kølvraa S; Bischoff C; Bohr V A
[Telomere terminals and telomerase. The biological aging clock?]
Ugeskrift for laeger 1999;161(26):3987-91.
1999: Brosh R M; Orren D K; Nehlin J O; Ravn P H; Kenny M K; Machwe A; Bohr V A
Functional and physical interaction between WRN helicase and human replication protein A.
The Journal of biological chemistry 1999;274(26):18341-50.
1999: Balajee A S; May A; Bohr V A
DNA repair of pyrimidine dimers and 6-4 photoproducts in the ribosomal DNA.
Nucleic acids research 1999;27(12):2511-20.
1999: Cullinane C; Mazur S J; Essigmann J M; Phillips D R; Bohr V A
Inhibition of RNA polymerase II transcription in human cell extracts by cisplatin DNA damage.
Biochemistry 1999;38(19):6204-12.
1999: Souza-Pinto N C; Croteau D L; Hudson E K; Hansford R G; Bohr V A
Age-associated increase in 8-oxo-deoxyguanosine glycosylase/AP lyase activity in rat mitochondria.
Nucleic acids research 1999;27(8):1935-42.
1999: Stierum R H; Croteau D L; Bohr V A
Purification and characterization of a mitochondrial thymine glycol endonuclease from rat liver.
The Journal of biological chemistry 1999;274(11):7128-36.
1999: Dianov G; Bischoff C; Sunesen M; Bohr V A
Repair of 8-oxoguanine in DNA is deficient in Cockayne syndrome group B cells.
Nucleic acids research 1999;27(5):1365-8.
1999: Bohr V A; Dianov G L
Oxidative DNA damage processing in nuclear and mitochondrial DNA.
Biochimie 1999;81(1-2):155-60.
1999: Custer L; Zajc B; Sayer J M; Cullinane C; Phillips D R; Cheh A M; Jerina D M; Bohr V A; Mazur S J
Stereospecific differences in repair by human cell extracts of synthesized oligonucleotides containing trans-opened 7,8,9, 10-tetrahydrobenzo[a]pyrene 7,8-diol 9,10-epoxide N2-dG adduct stereoisomers located within the human K-ras codon 12 sequence.
Biochemistry 1999;38(2):569-81.
1999: Anson R M; Bohr V A
Gene-specific and mitochondrial repair of oxidative DNA damage.
Methods in molecular biology (Clifton, N.J.) 1999;113():257-79.
1998: Hudson E K; Hogue B A; Souza-Pinto N C; Croteau D L; Anson R M; Bohr V A; Hansford R G
Age-associated change in mitochondrial DNA damage.
Free radical research 1998;29(6):573-9.
1998: Bohr V; Anson R M; Mazur S; Dianov G
Oxidative DNA damage processing and changes with aging.
Toxicology letters 1998;102-103():47-52.
1998: Balajee A S; May A; Dianova I; Bohr V A
Efficient PCNA complex formation is dependent upon both transcription coupled repair and genome overall repair.
Mutation research 1998;409(3):135-46.
1998: Dianov G; Bischoff C; Piotrowski J; Bohr V A
Repair pathways for processing of 8-oxoguanine in DNA by mammalian cell extracts.
The Journal of biological chemistry 1998;273(50):33811-6.
1998: Winter D B; Gearhart P J; Bohr V A
Homogeneous rate of degradation of nuclear DNA during apoptosis.
Nucleic acids research 1998;26(19):4422-5.
1998: Bohr V A; Dianov G; Balajee A; May A; Orren D K
DNA repair and transcription in human premature aging disorders.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 1998;3(1):11-3.
1998: Balajee A S; May A; Bohr V A
Fine structural analysis of DNA repair in mammalian cells.
Mutation research 1998;404(1-2):3-11.
1998: Winter D B; Phung Q H; Umar A; Baker S M; Tarone R E; Tanaka K; Liskay R M; Kunkel T A; Bohr V A; Gearhart P J
Altered spectra of hypermutation in antibodies from mice deficient for the DNA mismatch repair protein PMS2.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(12):6953-8.
1998: Phung Q H; Winter D B; Cranston A; Tarone R E; Bohr V A; Fishel R; Gearhart P J
Increased hypermutation at G and C nucleotides in immunoglobulin variable genes from mice deficient in the MSH2 mismatch repair protein.
The Journal of experimental medicine 1998;187(11):1745-51.
1998: Jaiswal M; Lipinski L J; Bohr V A; Mazur S J
Efficient in vitro repair of 7-hydro-8-oxodeoxyguanosine by human cell extracts: involvement of multiple pathways.
Nucleic acids research 1998;26(9):2184-91.
1998: Cullinane C; Bohr V A
DNA interstrand cross-links induced by psoralen are not repaired in mammalian mitochondria.
Cancer research 1998;58(7):1400-4.
1998: Anson R M; Croteau D L; Stierum R H; Filburn C; Parsell R; Bohr V A
Homogenous repair of singlet oxygen-induced DNA damage in differentially transcribed regions and strands of human mitochondrial DNA.
Nucleic acids research 1998;26(2):662-8.
1997: Croteau D L; ap Rhys C M; Hudson E K; Dianov G L; Hansford R G; Bohr V A
An oxidative damage-specific endonuclease from rat liver mitochondria.
The Journal of biological chemistry 1997;272(43):27338-44.
1997: Croteau D L; Bohr V A
Repair of oxidative damage to nuclear and mitochondrial DNA in mammalian cells.
The Journal of biological chemistry 1997;272(41):25409-12.
1997: Orren D K; Petersen L N; Bohr V A
Persistent DNA damage inhibits S-phase and G2 progression, and results in apoptosis.
Molecular biology of the cell 1997;8(6):1129-42.
1997: Gilchrest B A; Bohr V A
Aging processes, DNA damage, and repair.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1997;11(5):322-30.
1997: Balajee A S; May A; Dianov G L; Friedberg E C; Bohr V A
Reduced RNA polymerase II transcription in intact and permeabilized Cockayne syndrome group B cells.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(9):4306-11.
1997: Beecham E J; Owens J D; Shaughnessy J D; Huppi K; Bohr V A; Mushinski J F
Decoupling of DNA excision repair and RNA transcription in translocation breaksite regions of plasmacytoma-susceptible BALB/cAnPt mice.
Carcinogenesis 1997;18(4):687-94.
1997: Cullinane C; Weber C A; Dianov G; Bohr V A
Restoration of preferential and strand specific gene repair in group 2 Chinese hamster ovary mutants (UV5) by the XPD (ERCC2) gene.
Carcinogenesis 1997;18(4):681-6.
1996: Petersen L N; Mamenta E L; Stevnsner T; Chaney S G; Bohr V A
Increased gene specific repair of cisplatin induced interstrand crosslinks in cisplatin resistant cell lines, and studies on carrier ligand specificity.
Carcinogenesis 1996;17(12):2597-602.
1996: Taffe B G; Larminat F; Laval J; Croteau D L; Anson R M; Bohr V A
Gene-specific nuclear and mitochondrial repair of formamidopyrimidine DNA glycosylase-sensitive sites in Chinese hamster ovary cells.
Mutation research 1996;364(3):183-92.
1996: Orren D K; Dianov G L; Bohr V A
The human CSB (ERCC6) gene corrects the transcription-coupled repair defect in the CHO cell mutant UV61.
Nucleic acids research 1996;24(17):3317-22.
1996: Bartosova Z; Pirsel M; Reinhold W; Stetler-Stevenson M; Zajac-Kaye M; May A; Horak I D; Bohr V A
Gene-specific repair in human CD4+ lymphocytes reflects transcription and proliferation.
Mutation research 1996;363(3):191-9.
1996: Kruk P A; Balajee A S; Rao K S; Bohr V A
Telomere reduction and telomerase inactivation during neuronal cell differentiation.
Biochemical and biophysical research communications 1996;224(2):487-92.
1996: Ferguson A W; Flatow U; MacDonald N J; Larminat F; Bohr V A; Steeg P S
Increased sensitivity to cisplatin by nm23-transfected tumor cell lines.
Cancer research 1996;56(13):2931-5.
1996: Webb D K; Evans M K; Bohr V A
DNA repair fine structure in Werner's syndrome cell lines.
Experimental cell research 1996;224(2):272-8.
1996: Evans M K; Chin K V; Gottesman M M; Bohr V A
Gene-specific DNA repair and steady state transcription of the MDR1 gene in human tumor cell lines.
Oncogene 1996;12(3):651-8.
1995: Petersen L N; Stevnsner T; Bohr V A
DNA repair in a UV resistant Chinese hamster ovary cell line.
Carcinogenesis 1995;16(12):3075-81.
1995: Bohr V A
DNA repair fine structure and its relations to genomic instability.
Carcinogenesis 1995;16(12):2885-92.
1995: Bohr V A; Anson R M
DNA damage, mutation and fine structure DNA repair in aging.
Mutation research 1995;338(1-6):25-34.
1995: Petersen L N; Orren D K; Bohr V A
Gene-specific and strand-specific DNA repair in the G1 and G2 phases of the cell cycle.
Molecular and cellular biology 1995;15(7):3731-7.
1995: Orren D K; Petersen L N; Bohr V A
A UV-responsive G2 checkpoint in rodent cells.
Molecular and cellular biology 1995;15(7):3722-30.
1995: Link C J; Evans M K; Cook J A; Muldoon R; Stevnsner T; Bohr V A
Caffeine inhibits gene-specific repair of UV-induced DNA damage in hamster cells and in human xeroderma pigmentosum group C cells.
Carcinogenesis 1995;16(5):1149-55.
1995: Larminat F; Beecham E J; Link C J; May A; Bohr V A
DNA repair in the endogenous and episomal amplified c-myc oncogene loci in human tumor cells.
Oncogene 1995;10(8):1639-45.
1995: Link C J; Bohr V A
3"-Azido-3'-deoxythymidine and 2',3'-dideoxycytidine do not inhibit gene-specific DNA repair in hamster cells.
Biochemical and biophysical research communications 1995;208(1):198-203.
1995: Link C J; Robbins J H; Bohr V A
Gene specific DNA repair of damage induced in familial Alzheimer disease cells by ultraviolet irradiation or by nitrogen mustard.
Mutation research 1995;336(2):115-21.
1995: Kruk P A; Rampino N J; Bohr V A
DNA damage and repair in telomeres: relation to aging.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(1):258-62.
1994: Stevnsner T; Ding R; Smulson M; Bohr V A
Inhibition of gene-specific repair of alkylation damage in cells depleted of poly(ADP-ribose) polymerase.
Nucleic acids research 1994;22(22):4620-4.
1994: Rampino N J; Bohr V A
Rapid gene-specific repair of cisplatin lesions at the human DUG/DHFR locus comprising the divergent upstream gene and dihydrofolate reductase gene during early G1 phase of the cell cycle assayed by using the exonucleolytic activity of T4 DNA polymerase.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(23):10977-81.
1994: Larminat F; Bohr V A
Role of the human ERCC-1 gene in gene-specific repair of cisplatin-induced DNA damage.
Nucleic acids research 1994;22(15):3005-10.
1994: Evans M K; Bohr V A
Gene-specific DNA repair of UV-induced cyclobutane pyrimidine dimers in some cancer-prone and premature-aging human syndromes.
Mutation research 1994;314(3):221-31.
1994: Beecham E J; Jones G M; Link C; Huppi K; Potter M; Mushinski J F; Bohr V A
DNA repair defects associated with chromosomal translocation breaksite regions.
Molecular and cellular biology 1994;14(2):1204-12.
1993: Evans M K; Taffe B G; Harris C C; Bohr V A
DNA strand bias in the repair of the p53 gene in normal human and xeroderma pigmentosum group C fibroblasts.
Cancer research 1993;53(22):5377-81.
1993: Lee K B; Parker R J; Bohr V; Cornelison T; Reed E
Cisplatin sensitivity/resistance in UV repair-deficient Chinese hamster ovary cells of complementation groups 1 and 3.
Carcinogenesis 1993;14(10):2177-80.
1993: Stevnsner T; Bohr V A
Studies on the role of topoisomerases in general, gene- and strand-specific DNA repair.
Carcinogenesis 1993;14(9):1841-50.
1993: Stevnsner T; May A; Petersen L N; Larminat F; Pirsel M; Bohr V A
Repair of ribosomal RNA genes in hamster cells after UV irradiation, or treatment with cisplatin or alkylating agents.
Carcinogenesis 1993;14(8):1591-6.
1993: Zhen W; Evans M K; Haggerty C M; Bohr V A
Deficient gene specific repair of cisplatin-induced lesions in Xeroderma pigmentosum and Fanconi's anemia cell lines.
Carcinogenesis 1993;14(5):919-24.
1993: Evans M K; Robbins J H; Ganges M B; Tarone R E; Nairn R S; Bohr V A
Gene-specific DNA repair in xeroderma pigmentosum complementation groups A, C, D, and F. Relation to cellular survival and clinical features.
The Journal of biological chemistry 1993;268(7):4839-47.
1993: Larminat F; Zhen W; Bohr V A
Gene-specific DNA repair of interstrand cross-links induced by chemotherapeutic agents can be preferential.
The Journal of biological chemistry 1993;268(4):2649-54.
1993: May A; Nairn R S; Okumoto D S; Wassermann K; Stevnsner T; Jones J C; Bohr V A
Repair of individual DNA strands in the hamster dihydrofolate reductase gene after treatment with ultraviolet light, alkylating agents, and cisplatin.
The Journal of biological chemistry 1993;268(3):1650-7.
1993: Dabholkar M; Bostick-Bruton F; Weber C; Egwuagu C; Bohr V A; Reed E
Expression of excision repair genes in non-malignant bone marrow from cancer patients.
Mutation research 1993;293(2):151-60.
1993: Nouso K; Bohr V A; Schut H A; Snyderwine E G
Quantitation of 2-amino-3-methylimidazo[4,5-f]quinoline and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline DNA adducts in specific sequences using alkali or uvrABC excinuclease.
Molecular carcinogenesis 1993;7(2):126-34.
1992: Wassermann K; Pirsel M; Bohr V A
Overexpression of metallothionein in Chinese hamster ovary cells and its effect on nitrogen mustard-induced cytotoxicity: role of gene-specific damage and repair.
Cancer research 1992;52(24):6853-9.
1992: Link C J; Mitchell D L; Nairn R S; Bohr V A
Preferential and strand-specific DNA repair of (6-4) photoproducts detected by a photochemical method in the hamster DHFR gene.
Carcinogenesis 1992;13(11):1975-80.
1992: LeDoux S P; Wilson G L; Beecham E J; Stevnsner T; Wassermann K; Bohr V A
Repair of mitochondrial DNA after various types of DNA damage in Chinese hamster ovary cells.
Carcinogenesis 1992;13(11):1967-73.
1992: Dabholkar M; Bostick-Bruton F; Weber C; Bohr V A; Egwuagu C; Reed E
ERCC1 and ERCC2 expression in malignant tissues from ovarian cancer patients.
Journal of the National Cancer Institute 1992;84(19):1512-7.
1992: Zhen W; Link C J; O'Connor P M; Reed E; Parker R; Howell S B; Bohr V A
Increased gene-specific repair of cisplatin interstrand cross-links in cisplatin-resistant human ovarian cancer cell lines.
Molecular and cellular biology 1992;12(9):3689-98.
1992: Snyderwine E G; Bohr V A
Gene- and strand-specific damage and repair in Chinese hamster ovary cells treated with 4-nitroquinoline 1-oxide.
Cancer research 1992;52(15):4183-9.
1991: O'Connor P M; Wassermann K; Sarang M; Magrath I; Bohr V A; Kohn K W
Relationship between DNA cross-links, cell cycle, and apoptosis in Burkitt's lymphoma cell lines differing in sensitivity to nitrogen mustard.
Cancer research 1991;51(24):6550-7.
1991: Bohr V A
Gene specific DNA repair.
Carcinogenesis 1991;12(11):1983-92.
1991: Link C J; Burt R K; Bohr V A
Gene-specific repair of DNA damage induced by UV irradiation and cancer chemotherapeutics.
Cancer cells (Cold Spring Harbor, N.Y. : 1989) 1991;3(11):427-36.
1991: Jones J C; Stevnsner T; Mattern M R; Bohr V A
Effect of specific enzyme inhibitors on replication, total genome DNA repair and on gene-specific DNA repair after UV irradiation in CHO cells.
Mutation research 1991;255(2):155-62.
1991: Beecham E J; Mushinski J F; Shacter E; Potter M; Bohr V A
DNA repair in the c-myc proto-oncogene locus: possible involvement in susceptibility or resistance to plasmacytoma induction in BALB/c mice.
Molecular and cellular biology 1991;11(6):3095-104.
1991: Burt R K; Poirier M C; Link C J; Bohr V A
Antineoplastic drug resistance and DNA repair.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1991;2(5):325-34.
1991: Jones J C; Zhen W P; Reed E; Parker R J; Sancar A; Bohr V A
Gene-specific formation and repair of cisplatin intrastrand adducts and interstrand cross-links in Chinese hamster ovary cells.
The Journal of biological chemistry 1991;266(11):7101-7.
1991: LeDoux S P; Thangada M; Bohr V A; Wilson G L
Heterogeneous repair of methylnitrosourea-induced alkali-labile sites in different DNA sequences.
Cancer research 1991;51(3):775-9.
1991: Pettepher C C; LeDoux S P; Bohr V A; Wilson G L
Repair of alkali-labile sites within the mitochondrial DNA of RINr 38 cells after exposure to the nitrosourea streptozotocin.
The Journal of biological chemistry 1991;266(5):3113-7.
1991: Bohr V A
Gene specific damage and repair after treatment of cells with UV and chemotherapeutical agents.
Advances in experimental medicine and biology 1991;283():225-33.
1990: Wassermann K; Kohn K W; Bohr V A
Heterogeneity of nitrogen mustard-induced DNA damage and repair at the level of the gene in Chinese hamster ovary cells.
The Journal of biological chemistry 1990;265(23):13906-13.
1990: Bohr V A
DNA repair at the level of the gene: molecular and clinical considerations.
Journal of cancer research and clinical oncology 1990;116(4):384-91.
1990: Beecham E J; Mushinski J F; Shacter E; Potter M; Bohr V A
DNA repair in the c-myc locus.
Current topics in microbiology and immunology 1990;166():285-91.
1990: Parker R J; Poirier M C; Bostick-Bruton F; Vionnet J; Bohr V A; Reed E
Peripheral blood leukocytes as a surrogate marker for cisplatin drug resistance: studies of adduct levels and the repair gene ERCC1.
Basic life sciences 1990;53():251-61.
1989: Thomas D C; Okumoto D S; Sancar A; Bohr V A
Preferential DNA repair of (6-4) photoproducts in the dihydrofolate reductase gene of Chinese hamster ovary cells.
The Journal of biological chemistry 1989;264(30):18005-10.
1989: Bohr V A; Evans M K; Fornace A J
DNA repair and its pathogenetic implications.
Laboratory investigation; a journal of technical methods and pathology 1989;61(2):143-61.
1988: Bohr V A; Chu E H; van Duin M; Hanawalt P C; Okumoto D S
Human repair gene restores normal pattern of preferential DNA repair in repair defective CHO cells.
Nucleic acids research 1988;16(15):7397-403.
1987: Bohr V A
Preferential DNA repair in active genes.
Danish medical bulletin 1987;34(6):309-20.
1987: Bohr V A; Phillips D H; Hanawalt P C
Heterogeneous DNA damage and repair in the mammalian genome.
Cancer research 1987;47(24 Pt 1):6426-36.
1987: Okumoto D S; Bohr V A
DNA repair in the metallothionein gene increases with transcriptional activation.
Nucleic acids research 1987;15(23):10021-30.

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