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James Squires

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Matthew A Gray; E James Squires
Effects of nuclear receptor transactivation on boar taint metabolism and gene expression in porcine hepatocytes.
Matthew A Gray; E James Squires
Effects of nuclear receptor transactivation on steroid hormone synthesis and gene expression in porcine Leydig cells.
P Wiercinska; Yanping Lou; E James Squires
The roles of different porcine cytochrome P450 enzymes and cytochrome b5A in skatole metabolism.

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All Publications

2013: Matthew A Gray; E James Squires
Effects of nuclear receptor transactivation on boar taint metabolism and gene expression in porcine hepatocytes.
The Journal of steroid biochemistry and molecular biology 2013;133():110-9.
2013: Matthew A Gray; E James Squires
Effects of nuclear receptor transactivation on steroid hormone synthesis and gene expression in porcine Leydig cells.
The Journal of steroid biochemistry and molecular biology 2013;133():93-100.
2012: P Wiercinska; Yanping Lou; E James Squires
The roles of different porcine cytochrome P450 enzymes and cytochrome b5A in skatole metabolism.
Animal : an international journal of animal bioscience 2012;6(5):834-45.
2011: K Jen; E James Squires
In vitro assessment of the effectiveness of non-nutritive sorbent materials as binding agents for boar taint compounds.
Animal : an international journal of animal bioscience 2011;5(11):1821-8.
2011: K Jen; E James Squires
Efficacy of non-nutritive sorbent materials as intestinal-binding agents for the control of boar taint.
Animal : an international journal of animal bioscience 2011;5(11):1814-20.
2011: Natalie Keirstead; M Anthony Hayes; G E Vandervoort; Andrew S Brooks; E James Squires; Brandon N Lillie
Single nucleotide polymorphisms in collagenous lectins and other innate immune genes in pigs with common infectious diseases.
Veterinary immunology and immunopathology 2011;142(1-2):1-13.
2010: Matthew A Gray; Callie B Pollock; Lawrence B Schook; E James Squires
Characterization of porcine pregnane X receptor, farnesoid X receptor and their splice variants.
Experimental biology and medicine (Maywood, N.J.) 2010;235(6):718-36.
2010: Maxwell C K Leung; Kiera-Lynne Bowley; E James Squires
Examination of testicular gene expression patterns in Yorkshire pigs with high and low levels of boar taint.
Animal biotechnology 2010;21(2):77-87.
2009: M A Gray; J N Peacock; E James Squires
Characterization of the porcine constitutive androstane receptor (CAR) and its splice variants.
Xenobiotica; the fate of foreign compounds in biological systems 2009;39(12):915-30.
2009: G Zamaratskaia; E James Squires
Biochemical, nutritional and genetic effects on boar taint in entire male pigs.
Animal : an international journal of animal bioscience 2009;3(11):1508-21.
2009: E Yeh; R Darren Wood; S Leeson; E James Squires
Effect of dietary omega-3 and omega-6 fatty acids on clotting activities of Factor V, VII and X in fatty liver haemorrhagic syndrome-susceptible laying hens.
British poultry science 2009;50(3):382-92.
2009: A Heinrich; Todd F Duffield; Kerry D Lissemore; E James Squires; Suzanne T Millman
The impact of meloxicam on postsurgical stress associated with cautery dehorning.
Journal of dairy science 2009;92(2):540-7.
2009: M J Billen; E James Squires
The role of porcine cytochrome b5A and cytochrome b5B in the regulation of cytochrome P45017A1 activities.
The Journal of steroid biochemistry and molecular biology 2009;113(1-2):98-104.
2008: Peter P Purslow; J A B Robinson; E James Squires; J Brown; Ming C Cha; C F M Delange; IB Mandell; TM Widowski; G Vandervoort
Modelling quality variations in commercial Ontario pork production.
Meat science 2008;80(1):123-31.
2008: G Zamaratskaia; Ellen Dahl; Andrzej Madej; E James Squires; Oystein Andresen
Studies on 5alpha-androst-16-en-3-one binding to porcine serum, plasma and testicular cytosolic fraction and to human serum.
The Journal of steroid biochemistry and molecular biology 2008;111(1-2):24-8.
2008: G Zamaratskaia; H K Andersson; G Chen; R K Juneja; Y Lou; Kerstin Lundström; J Peacock; L Rydhmer; E James Squires
Effect of polymorphism in the porcine cytochrome b5 ( CYB5A) gene on androstenone and skatole concentrations and sexual development in Swedish pig populations.
Animal : an international journal of animal bioscience 2008;2(2):190-6.
2008: J Peacock; Yanping Lou; Kerstin Lundström; E James Squires
The effect of a c.-8G>T polymorphism on the expression of cytochrome b5A and boar taint in pigs.
Animal genetics 2008;39(1):15-21.
2007: G Zamaratskaia; W James Gilmore; Kerstin Lundström; E James Squires
Effect of testicular steroids on catalytic activities of cytochrome P450 enzymes in porcine liver microsomes.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2007;45(4):676-81.
2007: G Zamaratskaia; Y Lou; G Chen; Ø Andresen; Kerstin Lundström; E James Squires
Effect of hCG stimulation on plasma androstenone concentrations and cytochrome b5 levels in testicular tissue.
Reproduction in domestic animals = Zuchthygiene 2007;42(1):105-8.
2007: Brandon N Lillie; Natalie D Keirstead; E James Squires; M Anthony Hayes
Gene polymorphisms associated with reduced hepatic expression of porcine mannan-binding lectin C.
Developmental and comparative immunology 2007;31(8):830-46.
2006: Brandon N Lillie; Natalie D Keirstead; E James Squires; M Anthony Hayes
Single-nucleotide polymorphisms in porcine mannan-binding lectin A.
Immunogenetics 2006;58(12):983-93.
2006: F Lanthier; Yanping Lou; M A Terner; E James Squires
Characterizing developmental changes in plasma and tissue skatole concentrations in the prepubescent intact male pig.
Journal of animal science 2006;84(7):1699-708.
2006: Zhihong Lin; Yanping Lou; E James Squires
Functional polymorphism in porcine CYP2E1 gene: Its association with skatole levels.
The Journal of steroid biochemistry and molecular biology 2006;99(4-5):231-7.
2006: Michael A Terner; W James Gilmore; Yanping Lou; E James Squires
The role of CYP2A and CYP2E1 in the metabolism of 3-methylindole in primary cultured porcine hepatocytes.
Drug metabolism and disposition: the biological fate of chemicals 2006;34(5):848-54.
2006: PA Sinclair; W James Gilmore; Z Lin; Yanping Lou; E James Squires
Molecular cloning and regulation of porcine SULT2A1: relationship between SULT2A1 expression and sulfoconjugation of androstenone.
Journal of molecular endocrinology 2006;36(2):301-11.
2005: Zhihong Lin; Yanping Lou; E James Squires
Identification of a single nucleotide polymorphism in porcine testis cytochrome P450-c17 (CYP17) and its effect on steroidogenesis.
Biochemical genetics 2005;43(9-10):531-42.
2005: PA Sinclair; E James Squires; James I Raeside; Rick Renaud
Synthesis of free and sulphoconjugated 16-androstene steroids by the Leydig cells of the mature domestic boar.
The Journal of steroid biochemistry and molecular biology 2005;96(2):217-28.
2005: PA Sinclair; S Hancock; W James Gilmore; E James Squires
Metabolism of the 16-androstene steroids in primary cultured porcine hepatocytes.
The Journal of steroid biochemistry and molecular biology 2005;96(1):79-87.
2005: Zhihong Lin; Yanping Lou; John Peacock; E James Squires
A novel polymorphism in the 5' untranslated region of the porcine cytochrome b5 (CYB5) gene is associated with decreased fat androstenone level.
Mammalian genome : official journal of the International Mammalian Genome Society 2005;16(5):367-73.
2005: PA Sinclair; E James Squires
Testicular sulfoconjugation of the 16-androstene steroids by hydroxysteroid sulfotransferase: its effect on the concentrations of 5alpha-androstenone in plasma and fat of the mature domestic boar.
Journal of animal science 2005;83(2):358-65.
2005: Jennifer D Stewart; Yanping Lou; E James Squires; Paul M Coussens
Using human microarrays to identify differentially expressed genes associated with increased steroidogenesis in boars.
Animal biotechnology 2005;16(2):139-51.
2004: Zhihong Lin; Yanping Lou; E James Squires
Molecular cloning, expression and functional characterization of the cytochrome P450 2A6 gene in pig liver.
Animal genetics 2004;35(4):314-6.
2004: G Zamaratskaia; J Babol; Andrzej Madej; E James Squires; Kerstin Lundström
Age-related variation of plasma concentrations of skatole, androstenone, testosterone, oestradiol-17 beta, oestrone sulphate, dehydroepiandrosterone sulphate, triiodothyronine and IGF-1 in six entire male pigs.
Reproduction in domestic animals = Zuchthygiene 2004;39(3):168-72.
2003: A E Thomson; Patricia A Gentry; E James Squires
Comparison of the coagulation profile of fatty liver haemorrhagic syndrome-susceptible laying hens and normal laying hens.
British poultry science 2003;44(4):626-33.
2003: B E Schumann; E James Squires; S Leeson; B Hunter
Effect of hens fed dietary flaxseed with and without a fatty liver supplement on hepatic, plasma and production characteristics relevant to fatty liver haemorrhagic syndrome in laying hens.
British poultry science 2003;44(2):234-44.
2003: Gonzalo J Diaz; E James Squires
Phase II in vitro metabolism of 3-methylindole metabolites in porcine liver.
Xenobiotica; the fate of foreign compounds in biological systems 2003;33(5):485-98.
2002: H V L N Swamy; Trevor K Smith; EJ MacDonald; Herman J Boermans; E James Squires
Effects of feeding a blend of grains naturally contaminated with Fusarium mycotoxins on swine performance, brain regional neurochemistry, and serum chemistry and the efficacy of a polymeric glucomannan mycotoxin adsorbent.
Journal of animal science 2002;80(12):3257-67.
2002: J Babol; E James Squires; E A Gullett
Factors affecting the level of boar taint in entire male pigs as assessed by consumer sensory panel.
Meat science 2002;61(1):33-40.
2002: A E Thomson; E James Squires; Patricia A Gentry
Assessment of factor V, VII and X activities, the key coagulant proteins of the tissue factor pathway in poultry plasma.
British poultry science 2002;43(2):313-21.
2001: PA Sinclair; E James Squires; James I Raeside
Early postnatal plasma concentrations of testicular steroid hormones, pubertal development, and carcass leanness as potential indicators of boar taint in market weight intact male pigs.
Journal of animal science 2001;79(7):1868-76.
2001: E James Squires; RJ Julian
The effect of dietary chloride and bicarbonate on blood pH, haematological variables, pulmonary hypertension and ascites in broiler chickens.
British poultry science 2001;42(2):207-12.
2001: PA Sinclair; E James Squires; James I Raeside; Jack Britt; V G Hedgpeth
The effect of early postnatal treatment with a gonadotropin-releasing hormone agonist on the developmental profiles of testicular steroid hormones in the intact male pig.
Journal of animal science 2001;79(4):1003-10.
2001: JP Walton; RJ Julian; E James Squires
The effects of dietary flax oil and antioxidants on ascites and pulmonary hypertension in broilers using a low temperature model.
British poultry science 2001;42(1):123-9.
2000: B E Schuman; E James Squires; S Leeson
Effect of dietary flaxseed, flax oil and n-3 fatty acid supplement on hepatic and plasma characteristics relevant to fatty liver haemorrhagic syndrome in laying hens.
British poultry science 2000;41(4):465-72.
2000: Gonzalo J Diaz; E James Squires
Metabolism of 3-methylindole by porcine liver microsomes: responsible cytochrome P450 enzymes.
Toxicological sciences : an official journal of the Society of Toxicology 2000;55(2):284-92.
2000: Gonzalo J Diaz; E James Squires
Role of aldehyde oxidase in the hepatic in vitro metabolism of 3-methylindole in pigs.
Journal of agricultural and food chemistry 2000;48(3):833-7.
1999: Gonzalo J Diaz; E James Squires; RJ Julian
The use of selected plasma enzyme activities for the diagnosis of fatty liver-hemorrhagic syndrome in laying hens.
Avian diseases 1999;43(4):768-73.
1999: Gonzalo J Diaz; Konstantine Skordos; Garold S Yost; E James Squires
Identification of phase I metabolites of 3-methylindole produced by pig liver microsomes.
Drug metabolism and disposition: the biological fate of chemicals 1999;27(10):1150-6.
1999: JP Walton; J M Bond; RJ Julian; E James Squires
Effect of dietary flax oil and hypobaric hypoxia on pulmonary hypertension and haematological variables in broiler chickens.
British poultry science 1999;40(3):385-91.
1999: S M Davis; E James Squires
Association of cytochrome b5 with 16-androstene steroid synthesis in the testis and accumulation in the fat of male pigs.
Journal of animal science 1999;77(5):1230-5.
1999: J Babol; E James Squires; Kerstin Lundström
Relationship between metabolism of androstenone and skatole in intact male pigs.
Journal of animal science 1999;77(1):84-92.
1998: J Babol; E James Squires; Kerstin Lundström
Relationship between oxidation and conjugation metabolism of skatole in pig liver and concentrations of skatole in fat.
Journal of animal science 1998;76(3):829-38.
1998: J Babol; E James Squires; Kerstin Lundström
Hepatic metabolism of skatole in pigs by cytochrome P4502E1.
Journal of animal science 1998;76(3):822-8.
1997: E James Squires; Kerstin Lundström
Relationship between cytochrome P450IIE1 in liver and levels of skatole and its metabolites in intact male pigs.
Journal of animal science 1997;75(9):2506-11.
1997: S Leeson; AK Zubair; E James Squires; C Forsberg
Influence of dietary levels of fat, fiber, and copper sulfate and fat rancidity on cecal activity in the growing turkey.
Poultry science 1997;76(1):59-66.
1996: J M Bond; RJ Julian; E James Squires
Effect of dietary flax oil and hypobaric hypoxia on right ventricular hypertrophy and ascites in broiler chickens.
British poultry science 1996;37(4):731-41.
1996: J Babol; E James Squires; M Bonneau
Factors regulating the concentrations of 16-androstene steroids in submaxillary salivary glands of pigs.
Journal of animal science 1996;74(2):413-9.
1995: W J Meadus; E James Squires
Effect of phospholipids and organic solvents on the formation of 5,16-androstadien-3 beta-ol from pregnenolone in adrenal and testicular microsomes.
Steroids 1995;60(5):395-400.
1994: RJ Julian; E James Squires
Haematopoietic and right ventricular response to intermittent hypobaric hypoxia in meat-type chickens.
Avian pathology : journal of the W.V.P.A 1994;23(3):539-45.
1994: Gonzalo J Diaz; E James Squires; RJ Julian
Effect of selected dietary antioxidants on fatty liver-haemorrhagic syndrome in laying hens.
British poultry science 1994;35(4):621-9.
1994: Gonzalo J Diaz; E James Squires; RJ Julian; Herman J Boermans
Individual and combined effects of T-2 toxin and DAS in laying hens.
British poultry science 1994;35(3):393-405.
1994: P Gazdzinski; E James Squires; RJ Julian
Hepatic lipidosis in turkeys.
Avian diseases 1994;38(2):379-84.
1994: Gonzalo J Diaz; RJ Julian; E James Squires
Lesions in broiler chickens following experimental intoxication with cobalt.
Avian diseases 1994;38(2):308-16.
1994: Gonzalo J Diaz; RJ Julian; E James Squires
Cobalt-induced polycythaemia causing right ventricular hypertrophy and ascites in meat-type chickens.
Avian pathology : journal of the W.V.P.A 1994;23(1):91-104.
1994: Z Xu; E James Squires; T M Bray
Effects of dietary zinc deficiency on the hepatic microsomal cytochrome P450 2B in rats.
Canadian journal of physiology and pharmacology 1994;72(3):211-6.
1994: M Bonneau; R Dufour; C Chouvet; C Roulet; W Meadus; E James Squires
The effects of immunization against luteinizing hormone-releasing hormone on performance, sexual development, and levels of boar taint-related compounds in intact male pigs.
Journal of animal science 1994;72(1):14-20.
1993: RJ Julian; S M Mirsalimi; E James Squires
Effect of hypobaric hypoxia and diet on blood parameters and pulmonary hypertension-induced right ventricular hypertrophy in turkey poults and ducklings.
Avian pathology : journal of the W.V.P.A 1993;22(4):683-92.
1993: W J Meadus; J I Mason; E James Squires
Cytochrome P450c17 from porcine and bovine adrenal catalyses the formation of 5,16-androstadien-3 beta-ol from pregnenolone in the presence of cytochrome b5.
The Journal of steroid biochemistry and molecular biology 1993;46(5):565-72.
1993: H H Draper; E James Squires; H Mahmoodi; J Wu; S Agarwal; M Hadley
A comparative evaluation of thiobarbituric acid methods for the determination of malondialdehyde in biological materials.
Free radical biology & medicine 1993;15(4):353-63.
1993: S M Mirsalimi; RJ Julian; E James Squires
Effect of hypobaric hypoxia on slow- and fast-growing chickens fed diets with high and low protein levels.
Avian diseases 1993;37(3):660-7.
1993: E James Squires; J D Summers
A consideration of comparative metabolic aspects of the aetiology of sudden death syndrome and ascites in broilers.
The British veterinary journal 1993;149(3):285-94.
1992: RJ Julian; S M Mirsalimi; L G Bagley; E James Squires
Effect of hypoxia and diet on spontaneous turkey cardiomyopathy (round-heart disease).
Avian diseases 1992;36(4):1043-7.
1992: E James Squires; J Wu
Enhanced induction of hepatic lipid peroxidation by ferric nitrilotriacetate in chickens susceptible to fatty liver rupture.
British poultry science 1992;33(2):329-37.
1991: E James Squires; E A Gullett; K R Fisher; G D Partlow
Comparison of androst-16-ene steroid levels determined by a colorimetric assay with boar taint estimated by a trained sensory panel.
Journal of animal science 1991;69(3):1092-100.
1991: E James Squires; E V Valdes; J Wu; S Leeson
Research note: utility of the thiobarbituric acid test in the determination of the quality of fats and oils in feeds.
Poultry science 1991;70(1):180-3.
1990: E James Squires
High performance liquid chromatographic analysis of the malondialdehyde content of chicken liver.
Poultry science 1990;69(8):1371-6.
1990: E James Squires; M Negishi
Tissue-specific regulation of cytochrome P-450 dependent testosterone 15 alpha-hydroxylase.
Canadian journal of physiology and pharmacology 1990;68(6):769-76.
1989: E James Squires
Involvement of cytochrome P-450 in the synthesis of 5,16,androstadien-3 beta-ol from pregnenolone in pig testes microsomes.
Journal of steroid biochemistry 1989;33(4A):621-6.