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Kaila Srai

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

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Fourier Transform Infrared Spectroscopy

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Co-Publications
Name
35
Debnam, Edward
14
Epstein, O
10
Ramesh, Bala
9
Marks, Joanne
7
Rice-Evans, Catherine
6
Schümann, Klaus
6
Spencer, Jeremy
6
Sharp, Paul
6
Unwin, Robert
5
Simpson, Robert
5
Solanky, Nita
5
Kuhnle, Gunter
5
McArdle, Harry
5
Haris, PI
5
Bayele, Henry

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Publications

TOP 3
Chung Bomee; Chaston Timothy; Marks Joanne; Srai Surjit Kaila; Sharp Paul A
Hepcidin decreases iron transporter expression in vivo in mouse duodenum and spleen and in vitro in THP-1 macrophages and intestinal Caco-2 cells.
Bayele Henry K; Srai Surjit K S
Regulatory variation in hepcidin expression as a heritable quantitative trait.
Gambling Lorraine; Czopek Alicja; Andersen Henriette S; Holtrop Grietje; Srai S Kaila S; Krejpcio Zbigniew; McArdle Harry J
Fetal iron status regulates maternal iron metabolism during pregnancy in the rat.

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All Publications

2009: Chung Bomee; Chaston Timothy; Marks Joanne; Srai Surjit Kaila; Sharp Paul A
Hepcidin decreases iron transporter expression in vivo in mouse duodenum and spleen and in vitro in THP-1 macrophages and intestinal Caco-2 cells.
The Journal of nutrition 2009;139(8):1457-62.
2009: Bayele Henry K; Srai Surjit K S
Regulatory variation in hepcidin expression as a heritable quantitative trait.
Biochemical and biophysical research communications 2009;384(1):22-7.
2009: Gambling Lorraine; Czopek Alicja; Andersen Henriette S; Holtrop Grietje; Srai S Kaila S; Krejpcio Zbigniew; McArdle Harry J
Fetal iron status regulates maternal iron metabolism during pregnancy in the rat.
American journal of physiology. Regulatory, integrative and comparative physiology 2009;296(4):R1063-70.
2008: Chaston T; Chung B; Mascarenhas M; Marks J; Patel B; Srai S K; Sharp P
Evidence for differential effects of hepcidin in macrophages and intestinal epithelial cells.
Gut 2008;57(3):374-82.
2007: Goestemeyer A K; Marks J; Srai S K; Debnam E S; Unwin R J
GLUT2 protein at the rat proximal tubule brush border membrane correlates with protein kinase C (PKC)-betal and plasma glucose concentration.
Diabetologia 2007;50(10):2209-17.
2007: Bayele Henry K; Peyssonnaux Carole; Giatromanolaki Alexandra; Arrais-Silva Wagner W; Mohamed Hiba S; Collins Helen; Giorgio Selma; Koukourakis Michael; Johnson Randall S; Blackwell Jenefer M; Nizet Victor; Srai Surjit Kaila S
HIF-1 regulates heritable variation and allele expression phenotypes of the macrophage immune response gene SLC11A1 from a Z-DNA forming microsatellite.
Blood 2007;110(8):3039-48.
2007: Sharp Paul; Srai Surjit-Kaila
Molecular mechanisms involved in intestinal iron absorption.
World journal of gastroenterology : WJG 2007;13(35):4716-24.
2007: Marks J; Churchill L J; Srai S K; Biber J; Murer H; Jaeger P; Debnam E S; Unwin R J;
Intestinal phosphate absorption in a model of chronic renal failure.
Kidney international 2007;72(2):166-73.
2006: Bayele Henry K; McArdle Harry; Srai Surjit K S
Cis and trans regulation of hepcidin expression by upstream stimulatory factor.
Blood 2006;108(13):4237-45.
2006: Bekri Soumeya; Gual Philippe; Anty Rodolphe; Luciani Nathalie; Dahman Monsef; Ramesh Bala; Iannelli Antonio; Staccini-Myx Aline; Casanova Dominique; Ben Amor Imed; Saint-Paul Marie-Christine; Huet Pierre-Michel; Sadoul Jean-Louis; Gugenheim Jean; Srai Surjit Kaila S; Tran Albert; Le Marchand-Brustel Yannick
Increased adipose tissue expression of hepcidin in severe obesity is independent from diabetes and NASH.
Gastroenterology 2006;131(3):788-96.
2006: Marks Joanne; Srai Surjit K; Biber Jürg; Murer Heini; Unwin Robert J; Debnam Edward S
Intestinal phosphate absorption and the effect of vitamin D: a comparison of rats with mice.
Experimental physiology 2006;91(3):531-7.
2006: Johnston K L; Johnson D M; Marks J; Srai S K; Debnam E S; Sharp P A
Non-haem iron transport in the rat proximal colon.
European journal of clinical investigation 2006;36(1):35-40.
2006: Ettle Thomas; Elsenhans Bernd; Windisch Wilhelm; Srai Surjit K S; Schümann Klaus
Mobilisation of recently absorbed 59Fe in ex vivo perfused rat duodena and the influence of iron status and subsequently absorbed chelators.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2006;19(4):231-41.
2005: Dluzniewska Joanna; Sarnowska Anna; Beresewicz Malgorzata; Johnson Ian; Srai Surjit K S; Ramesh Bala; Goldspink Geoffrey; Górecki Dariusz C; Zablocka Barbara
A strong neuroprotective effect of the autonomous C-terminal peptide of IGF-1 Ec (MGF) in brain ischemia.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(13):1896-8.
2005: Leung P S; Srai S K; Mascarenhas M; Churchill L J; Debnam E S
Increased duodenal iron uptake and transfer in a rat model of chronic hypoxia is accompanied by reduced hepcidin expression.
Gut 2005;54(10):1391-5.
2005: Johnson Deborah M; Yamaji Sachie; Tennant Jason; Srai Surjit K; Sharp Paul A
Regulation of divalent metal transporter expression in human intestinal epithelial cells following exposure to non-haem iron.
FEBS letters 2005;579(9):1923-9.
2004: El Mohsen Manal Abd; Marks Joanne; Kuhnle Gunter; Rice-Evans Catherine; Moore Kevin; Gibson Glenn; Debnam Edward; Srai S Kaila
The differential tissue distribution of the citrus flavanone naringenin following gastric instillation.
Free radical research 2004;38(12):1329-40.
2004: Yamaji Sachie; Sharp Paul; Ramesh Bala; Srai Surjit Kaila
Inhibition of iron transport across human intestinal epithelial cells by hepcidin.
Blood 2004;104(7):2178-80.
2004: Johnson Deborah; Bayele Henry; Johnston Kelly; Tennant Jason; Srai Surjit Kaila; Sharp Paul
Tumour necrosis factor alpha regulates iron transport and transporter expression in human intestinal epithelial cells.
FEBS letters 2004;573(1-3):195-201.
2004: Laftah Abas H; Ramesh Bala; Simpson Robert J; Solanky Nita; Bahram Seiamak; Schümann Klaus; Debnam Edward S; Srai Surjit K S
Effect of hepcidin on intestinal iron absorption in mice.
Blood 2004;103(10):3940-4.
2004: Laftah Abas H; Raja Kishor B; Beaumont Nick; Simpson Robert J; Deacon Allan; Solanky Nita; Srai Surjit Kaila S; Peters Timothy J
The effects of inhibition of haem biosynthesis by griseofulvin on intestinal iron absorption.
Basic & clinical pharmacology & toxicology 2004;94(4):161-8.
2004: Rechner Andreas R; Smith Martin A; Kuhnle Gunter; Gibson Glenn R; Debnam Edward S; Srai S Kaila S; Moore Kevin P; Rice-Evans Catherine A
Colonic metabolism of dietary polyphenols: influence of structure on microbial fermentation products.
Free radical biology & medicine 2004;36(2):212-25.
2004: Turner C M; Ramesh B; Srai S K S; Burnstock G; Unwin R J
Altered ATP-sensitive P2 receptor subtype expression in the Han:SPRD cy/+ rat, a model of autosomal dominant polycystic kidney disease.
Cells, tissues, organs 2004;178(3):168-79.
2003: Marks Joanne; Carvou Nicolas J C; Debnam Edward S; Srai Surjit K; Unwin Robert J
Diabetes increases facilitative glucose uptake and GLUT2 expression at the rat proximal tubule brush border membrane.
The Journal of physiology 2003;553(Pt 1):137-45.
2003: Gambling Lorraine; Dunford Susan; Wallace Donna I; Zuur Grietje; Solanky Nita; Srai S Kaila S; McArdle Harry J
Iron deficiency during pregnancy affects postnatal blood pressure in the rat.
The Journal of physiology 2003;552(Pt 2):603-10.
2003: Laftah Abas H; Simpson Robert J; Beaumont Nick; Bahram Seiamak; Schümann Klaus; Srai S Kaila S
Hypoxic response of iron absorption is not affected by the Hfe gene knock-out in mice.
British journal of haematology 2003;123(1):170-2.
2003: Gambling Lorraine; Danzeisen Ruth; Fosset Cedric; Andersen Henriette S; Dunford Susan; Srai S Kaila S; MCArdle Harry J
Iron and copper interactions in development and the effect on pregnancy outcome.
The Journal of nutrition 2003;133(5 Suppl 1):1554S-6S.
2003: Simpson R J; Debnam E; Beaumont N; Bahram S; Schümann K; Srai S K S
Duodenal mucosal reductase in wild-type and Hfe knockout mice on iron adequate, iron deficient, and iron rich feeding.
Gut 2003;52(4):510-3.
2003: Simpson Robert J; Debnam Edward S; Laftah Abas H; Solanky Nita; Beaumont Nick; Bahram Seiamak; Schümann Klaus; Srai S Kaila S
Duodenal nonheme iron content correlates with iron stores in mice, but the relationship is altered by Hfe gene knock-out.
Blood 2003;101(8):3316-8.
2003: Marks J; Debnam E S; Dashwood M R; Srai S K; Unwin R J
Detection of glucagon receptor mRNA in the rat proximal tubule: potential role for glucagon in the control of renal glucose transport.
Clinical science (London, England : 1979) 2003;104(3):253-8.
2002: Tennant Jason; Stansfield Matthew; Yamaji Sachie; Srai Surjit Kaila; Sharp Paul
Effects of copper on the expression of metal transporters in human intestinal Caco-2 cells.
FEBS letters 2002;527(1-3):239-44.
2002: Lebeau A; Frank J; Biesalski H K; Weiss G; Srai S K S; Simpson R J; McKie A T; Bahram S; Gilfillan S; Schümann K
Long-term sequelae of HFE deletion in C57BL/6 x 129/O1a mice, an animal model for hereditary haemochromatosis.
European journal of clinical investigation 2002;32(8):603-12.
2002: Smith Michael W; Shenoy K Bhasker; Debnam Edward S; Dashwood Michael R; Churchill Linda J; Srai S Kaila
Divalent metal inhibition of non-haem iron uptake across the rat duodenal brush border membrane.
The British journal of nutrition 2002;88(1):51-6.
2002: Srai S K S; Bomford Adrian; McArdle Harry J
Iron transport across cell membranes: molecular understanding of duodenal and placental iron uptake.
Best practice & research. Clinical haematology 2002;15(2):243-59.
2002: Syed Basharut A; Beaumont Nick J; Patel Alpesh; Naylor Claire E; Bayele Henry K; Joannou Christopher L; Rowe Peter S N; Evans Robert W; Srai S Kaila S
Analysis of the human hephaestin gene and protein: comparative modelling of the N-terminus ecto-domain based upon ceruloplasmin.
Protein engineering 2002;15(3):205-14.
2001: Spencer J P; Schroeter H; Shenoy B; Srai S K; Debnam E S; Rice-Evans C
Epicatechin is the primary bioavailable form of the procyanidin dimers B2 and B5 after transfer across the small intestine.
Biochemical and biophysical research communications 2001;285(3):588-93.
2001: Gambling L; Danzeisen R; Gair S; Lea R G; Charania Z; Solanky N; Joory K D; Srai S K; McArdle H J
Effect of iron deficiency on placental transfer of iron and expression of iron transport proteins in vivo and in vitro.
The Biochemical journal 2001;356(Pt 3):883-9.
2001: Spencer J P; Schroeter H; Kuhnle G; Srai S K; Tyrrell R M; Hahn U; Rice-Evans C
Epicatechin and its in vivo metabolite, 3'-O-methyl epicatechin, protect human fibroblasts from oxidative-stress-induced cell death involving caspase-3 activation.
The Biochemical journal 2001;354(Pt 3):493-500.
2000: Kuhnle G; Spencer J P; Schroeter H; Shenoy B; Debnam E S; Srai S K; Rice-Evans C; Hahn U
Epicatechin and catechin are O-methylated and glucuronidated in the small intestine.
Biochemical and biophysical research communications 2000;277(2):507-12.
2000: Spencer J P; Chaudry F; Pannala A S; Srai S K; Debnam E; Rice-Evans C
Decomposition of cocoa procyanidins in the gastric milieu.
Biochemical and biophysical research communications 2000;272(1):236-41.
2000: Kuhnle G; Spencer J P; Chowrimootoo G; Schroeter H; Debnam E S; Srai S K; Rice-Evans C; Hahn U
Resveratrol is absorbed in the small intestine as resveratrol glucuronide.
Biochemical and biophysical research communications 2000;272(1):212-7.
2000: Smith M W; Debnam E S; Dashwood M R; Srai S K
Structural and cellular adaptation of duodenal iron uptake in rats maintained on an iron-deficient diet.
Pflügers Archiv : European journal of physiology 2000;439(4):449-54.
2000: Tandy S; Williams M; Leggett A; Lopez-Jimenez M; Dedes M; Ramesh B; Srai S K; Sharp P
Nramp2 expression is associated with pH-dependent iron uptake across the apical membrane of human intestinal Caco-2 cells.
The Journal of biological chemistry 2000;275(2):1023-9.
1999: Spencer J P; Chowrimootoo G; Choudhury R; Debnam E S; Srai S K; Rice-Evans C
The small intestine can both absorb and glucuronidate luminal flavonoids.
FEBS letters 1999;458(2):224-30.
1999: Choudhury R; Srai S K; Debnam E; Rice-Evans C A
Urinary excretion of hydroxycinnamates and flavonoids after oral and intravenous administration.
Free radical biology & medicine 1999;27(3-4):278-86.
1998: Brazier S P; Ramesh B; Haris P I; Lee D C; Srai S K
Secondary structure analysis of the putative membrane-associated domains of the inward rectifier K+ channel ROMK1.
The Biochemical journal 1998;335 ( Pt 2)():375-80.
1998: Abbott G W; Mercer E A; Miller R T; Ramesh B; Srai S K
Conformational changes in a mammalian voltage-dependent potassium channel inactivation peptide.
Biochemistry 1998;37(6):1640-5.
1997: Abbott G W; Bloemendal M; Van Stokkum I H; Mercer E A; Miller R T; Sewing S; Wolters M; Pongs O; Srai S K
Secondary structure, stability and tetramerisation of recombinant K(V)1.1 potassium channel cytoplasmic N-terminal fragment.
Biochimica et biophysica acta 1997;1341(1):71-8.
1997: Sharp P A; Boyer S; Srai S K; Baldwin S A; Debnam E S
Early diabetes-induced changes in rat jejunal glucose transport and the response to insulin.
The Journal of endocrinology 1997;154(1):19-25.
1997: Mercer E A; Abbott G W; Brazier S P; Ramesh B; Haris P I; Srai S K
Synthetic putative transmembrane region of minimal potassium channel protein (minK) adopts an alpha-helical conformation in phospholipid membranes.
The Biochemical journal 1997;325 ( Pt 2)():475-9.
1997: O'Riordan D K; Debnam E S; Sharp P A; Simpson R J; Taylor E M; Srai S K
Mechanisms involved in increased iron uptake across rat duodenal brush-border membrane during hypoxia.
The Journal of physiology 1997;500 ( Pt 2)():379-84.
1997: Dong R; Srai S K; Debnam E; Smith M
Transcriptional and translational control over sodium-glucose-linked transporter (SGLT1) gene expression in adult rat small intestine.
FEBS letters 1997;406(1-2):79-82.
1996: Boyer S; Sharp P A; Debnam E S; Baldwin S A; Srai S K
Streptozotocin diabetes and the expression of GLUT1 at the brush border and basolateral membranes of intestinal enterocytes.
FEBS letters 1996;396(2-3):218-22.
1996: Sharp P A; Debnam E S; Srai S K
Rapid enhancement of brush border glucose uptake after exposure of rat jejunal mucosa to glucose.
Gut 1996;39(4):545-50.
1995: van Haeringen B; de Lange F; van Stokkum I H; Srai S K; Evans R W; van Grondelle R; Bloemendal M
Dynamic structure of human serum transferrin from transient electric birefringence experiments.
Proteins 1995;23(2):233-40.
1995: O'Riordan D K; Sharp P; Sykes R M; Srai S K; Epstein O; Debnam E S
Cellular mechanisms underlying the increased duodenal iron absorption in rats in response to phenylhydrazine-induced haemolytic anaemia.
European journal of clinical investigation 1995;25(10):722-7.
1995: Abbott G W; Mercer E A; Wolters M; Sewing S; Pongs O; Srai S K
Structure analysis of a recombinant voltage-gated potassium channel (Kv1.1) N-terminus using FTIR spectroscopy and thermal denaturation.
Biochemical Society transactions 1995;23(3):479S.
1995: Mercer E A; Abbott G W; Ramesh B; Haris P I; Chapman D; Srai S K
Structural characterisation of a slowly activating potassium channel (IsK).
Biochemical Society transactions 1995;23(3):478S.
1995: Debnam E S; Smith M W; Sharp P A; Srai S K; Turvey A; Keable S J
The effects of streptozotocin diabetes on sodium-glucose transporter (SGLT1) expression and function in rat jejunal and ileal villus-attached enterocytes.
Pflügers Archiv : European journal of physiology 1995;430(2):151-9.
1995: Hamilton M I; Bradley N J; Srai S K; Thrasivoulou C; Pounder R E; Wakefield A J
Autoimmunity in ulcerative colitis: tropomyosin is not the major antigenic determinant of the Das monoclonal antibody, 7E12H12.
Clinical and experimental immunology 1995;99(3):404-11.
1994: Kozma M M; Chowrimootoo G; Debnam E S; Epstein O; Srai S K
Developmental changes in mucosal iron binding proteins in the guinea pig. Expression of transferrin, H and L ferritin and binding of iron to a low molecular weight protein.
Biochimica et biophysica acta 1994;1201(2):229-34.
1994: Hadden J M; Bloemendal M; Haris P I; van Stokkum I H; Chapman D; Srai S K
Structure and thermal stability of the extracellular fragment of human transferrin receptor at extracellular and endosomal pH.
FEBS letters 1994;350(2-3):235-9.
1994: Hadden J M; Bloemendal M; Haris P I; Srai S K; Chapman D
Fourier transform infrared spectroscopy and differential scanning calorimetry of transferrins: human serum transferrin, rabbit serum transferrin and human lactoferrin.
Biochimica et biophysica acta 1994;1205(1):59-67.
1992: Bingle C D; Kelly F; Epstein O; Srai S K
Induction of hepatic and pulmonary caeruloplasmin gene expression in developing guinea pigs following premature delivery.
Biochimica et biophysica acta 1992;1139(3):217-21.
1992: Chowrimootoo G; Gillett M; Debnam E S; Srai S K; Epstein O
Iron-transferrin binding to isolated guinea pig enterocytes and the regional localisation of intestinal iron transfer during ontogeny.
Biochimica et biophysica acta 1992;1116(3):256-60.
1992: Bingle C D; Srai S K; Epstein O
Copper metabolism in hypercupremic human livers. Studies of its subcellular distribution, association with binding proteins and expression of mRNAs.
Journal of hepatology 1992;15(1-2):94-101.
1992: Bala T K; Debnam E; Srai S K
Partial characterisation of brushborder membrane bound iron binding protein of guinea pig enterocytes.
Biochemical Society transactions 1992;20(2):177S.
1992: Chowrimootoo G; Debnam E S; Srai S K; Epstein O
Regional characteristics of intestinal iron absorption in the guinea-pig.
Experimental physiology 1992;77(1):177-83.
1991: Bingle C D; Epstein O; Srai S K; Gitlin J D
Hepatic caeruloplasmin-gene expression during development in the guinea-pig. Correlation with changes in hepatic copper metabolism.
The Biochemical journal 1991;276 ( Pt 3)():771-5.
1991: Debnam E S; Srai S K; Chowrimootoo G; Epstein O
Ontogeny of iron uptake across brush border membrane of guinea pig duodenum and its autoradiographic localisation.
Biology of the neonate 1991;59(1):30-6.
1990: Bingle C D; Epstein O; Srai S K
A developmental shift from low- to high-Mr copper binders in guinea-pig serum.
Biochemical Society transactions 1990;18(4):645.
1990: Chowrimootoo G; Debnam E; Epstein O; Srai S
Regional localization of iron absorption in the guinea-pig small intestine during development.
Biochemical Society transactions 1990;18(4):612-3.
1990: Chesta J; Debnam E S; Srai S K; Epstein O
Delayed stomach to caecum transit time in the diabetic rat. Possible role of hyperglucagonaemia.
Gut 1990;31(6):660-2.
1990: Bingle C D; Srai S K; Epstein O
Developmental changes in hepatic copper proteins in the guinea pig.
Journal of hepatology 1990;10(2):138-43.
1989: Chesta J; Srai S K; Burroughs A K; Scheuer P J; Epstein O
Copper overload in the developing guinea pig liver: a histological, histochemical and biochemical study.
Liver 1989;9(4):198-204.
1988: Srai S K; Debnam E S; Boss M; Epstein O
Age-related changes in the kinetics of iron absorption across the guinea pig proximal intestine in vivo.
Biology of the neonate 1988;53(1):53-9.
1988: Bingle C D; Srai S K; Whiteley G S; Epstein O
Neonatal and adult copper-64 metabolism in the pig and the possible relationship between the ontogeny of copper metabolism and Wilson's disease.
Biology of the neonate 1988;54(5):294-300.

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