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Ramaprasad Srinivasan

Research Profile

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TOP 3
Eric A Singer; Gopal N Gupta; Daniel Marchalik; Ramaprasad Srinivasan
Evolving therapeutic targets in renal cell carcinoma.
Qingyan Liu; Susanna Galli; William Marston Linehan; Ramaprasad Srinivasan; Maria Tsokos; Maria J Merino
Renal medullary carcinoma: molecular, immunohistochemistry, and morphologic correlation.
Toni K Choueiri; Peter Eisenberg; Keith T Flaherty; Naomi B Haas; Andrea L Harzstark; Kevin H Laubscher; W Marston Linehan; Theodore F Logan; David F McDermott; Paul S Meltzer; Maria J Merino; Lone H Ottesen; Brian I Rini; Jonathan E Rosenberg; Robert Ross; Laurie Sherman; Sandy Srinivas; Laurel M Adams; Donald P Bottaro; Ronald M Bukowski; Mark N Stein; Ulka Nitin Vaishampayan; Ramaprasad Srinivasan
Phase II and biomarker study of the dual MET/VEGFR2 inhibitor foretinib in patients with papillary renal cell carcinoma.

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All Publications

2013: Eric A Singer; Gopal N Gupta; Daniel Marchalik; Ramaprasad Srinivasan
Evolving therapeutic targets in renal cell carcinoma.
Current opinion in oncology 2013;25(3):273-80.
2013: Qingyan Liu; Susanna Galli; William Marston Linehan; Ramaprasad Srinivasan; Maria Tsokos; Maria J Merino
Renal medullary carcinoma: molecular, immunohistochemistry, and morphologic correlation.
The American journal of surgical pathology 2013;37(3):368-74.
2013: Toni K Choueiri; Peter Eisenberg; Keith T Flaherty; Naomi B Haas; Andrea L Harzstark; Kevin H Laubscher; W Marston Linehan; Theodore F Logan; David F McDermott; Paul S Meltzer; Maria J Merino; Lone H Ottesen; Brian I Rini; Jonathan E Rosenberg; Robert Ross; Laurie Sherman; Sandy Srinivas; Laurel M Adams; Donald P Bottaro; Ronald M Bukowski; Mark N Stein; Ulka Nitin Vaishampayan; Ramaprasad Srinivasan
Phase II and biomarker study of the dual MET/VEGFR2 inhibitor foretinib in patients with papillary renal cell carcinoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2013;31(2):181-6.
2013: Nick W Liu; Maria Merino; Peter A Pinto; Thomas Sanford; Ramaprasad Srinivasan; Vladimir Valero; Robert Worrell; Youfeng Yang; Olga Aprelikova; Charles Bechert; Kiranpreet Khurana; W Marston Linehan; Jack L Liu; Gennady Bratslavsky
Impact of ischemia and procurement conditions on gene expression in renal cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2013;19(1):42-9.
2012: Christopher J Ricketts; Laura S Schmidt; Brian Shuch; Ramaprasad Srinivasan; Catherine Stolle; Cathy D Vocke; Ming-Hui Wei; Youfeng Yang; Berton Zbar; Maria J Merino; Adam R Metwalli; Lindsay Middelton; Karel Pacak; Stephen E Pautler; James Peterson; Peter A Pinto; Gennady Bratslavsky; W Marston Linehan
Succinate dehydrogenase kidney cancer: an aggressive example of the Warburg effect in cancer.
The Journal of urology 2012;188(6):2063-71.
2012: Eric A Singer; Ramaprasad Srinivasan
Intravenous therapies for castration-resistant prostate cancer: toxicities and adverse events.
Urologic oncology 2012;30(4 Suppl):S15-9.
2012: Paul H Chung; W Marston Linehan; Peter A Pinto; Ramaprasad Srinivasan; Gennady Bratslavsky
Renal cell carcinoma with metastases to the gallbladder: four cases from the National Cancer Institute (NCI) and review of the literature.
Urologic oncology 2012;30(4):476-81.
2012: Eric A Singer; Gopal N Gupta; Ramaprasad Srinivasan
Targeted therapeutic strategies for the management of renal cell carcinoma.
Current opinion in oncology 2012;24(3):284-90.
2012: Brian Shuch; Julia C Friend; W Marston Linehan; Srinivas Vourganti; Lee M Zehngebot; Ramaprasad Srinivasan
Targeting the mTOR pathway in Chromophobe Kidney Cancer.
Journal of Cancer 2012;3():152-7.
2012: Brian Shuch; Gennady Bratslavsky; W Marston Linehan; Ramaprasad Srinivasan
Sarcomatoid renal cell carcinoma: a comprehensive review of the biology and current treatment strategies.
The oncologist 2012;17(1):46-54.
2011: E Cherkasova; J A Hong; A V Kudryavtseva; Michael I Lerman; W M Linehan; E Malinzak; M Merino; M L Nickerson; S Rao; David S Schrump; Vera Senchenko; Ramaprasad Srinivasan; Yoshiyuki Takahashi; X Tian; Richard W Childs
Inactivation of the von Hippel-Lindau tumor suppressor leads to selective expression of a human endogenous retrovirus in kidney cancer.
Oncogene 2011;30(47):4697-706.
2011: Wing-Hang Tong; Jane Trepel; Sophie Vaulont; Benoit Viollet; Manish Vira; Youfeng Yang; Rachid Sougrat; Carole Sourbier; Ramaprasad Srinivasan; Gennady Bratslavsky; Manik Ghosh; Suh Young Jeong; Yeong Sang Kim; Gennady Kovtunovych; Sunmin Lee; W Marston Linehan; Vladimir Valera Romero; Tracey A Rouault
The glycolytic shift in fumarate-hydratase-deficient kidney cancer lowers AMPK levels, increases anabolic propensities and lowers cellular iron levels.
Cancer cell 2011;20(3):315-27.
2011: Eric A Singer; Gopal N Gupta; Ramaprasad Srinivasan
Update on targeted therapies for clear cell renal cell carcinoma.
Current opinion in oncology 2011;23(3):283-9.
2011: Sara Brooks; W Marston Linehan; Ramaprasad Srinivasan; Heidi H Kong
Successful laser treatment of vandetanib-associated cutaneous pigmentation.
Archives of dermatology 2011;147(3):364-5.
2011: Eric A Singer; Gennady Bratslavsky; Lindsay Middelton; Ramaprasad Srinivasan; W Marston Linehan
Impact of genetics on the diagnosis and treatment of renal cancer.
Current urology reports 2011;12(1):47-55.
2011: Thomas Sanford; Ramaprasad Srinivasan; Vladimir Valera; Paul H Chung; W Marston Linehan; Ariel Reinish; Gennady Bratslavsky
Molecular sub-classification of renal epithelial tumors using meta-analysis of gene expression microarrays.
PloS one 2011;6(7):e21260.
2011: Gennady Bratslavsky; Thomas Sanford; Ramaprasad Srinivasan; Olga Aprelikova; Jack Liu; Martha Quezado; Maria Merino; W Marston Linehan
Differential genetic expression in large versus small clear cell renal cell carcinoma: results from microarray analysis.
Journal of Cancer 2011;2():271-9.
2011: Eric A Singer; Ramaprasad Srinivasan; Gennady Bratslavsky
Editorial comment.
The Journal of urology 2011;185(1):66.
2010: Eric A Singer; Gennady Bratslavsky; W Marston Linehan; Ramaprasad Srinivasan
Targeted therapies for non-clear renal cell carcinoma.
Targeted oncology 2010;5(2):119-29.
2010: W Marston Linehan; Ramaprasad Srinivasan; Laura S Schmidt
The genetic basis of kidney cancer: a metabolic disease.
Nature reviews. Urology 2010;7(5):277-85.
2010: W Marston Linehan; Gennady Bratslavsky; Peter A Pinto; Laura S Schmidt; Len Neckers; Donald Bottaro; Ramaprasad Srinivasan
Molecular diagnosis and therapy of kidney cancer.
Annual review of medicine 2010;61():329-43.
2010: Youfeng Yang; Vladimir A Valera; Hesed Padilla-Nash; Carole Sourbier; Cathy D Vocke; Manish Vira; Mones Abu-Asab; Gennady Bratslavsky; Maria Tsokos; Maria J Merino; Peter A Pinto; Ramaprasad Srinivasan; Thomas Ried; Len Neckers; W Marston Linehan
UOK 262 cell line, fumarate hydratase deficient (FH-/FH-) hereditary leiomyomatosis renal cell carcinoma: in vitro and in vivo model of an aberrant energy metabolic pathway in human cancer.
Cancer genetics and cytogenetics 2010;196(1):45-55.
2009: Sivasubramanian Baskar; Jessica M Suschak; Ivan Samija; Ramaprasad Srinivasan; Richard W Childs; Steven Z Pavletic; Michael Bishop; Christoph Rader
A human monoclonal antibody drug and target discovery platform for B-cell chronic lymphocytic leukemia based on allogeneic hematopoietic stem cell transplantation and phage display.
Blood 2009;114(20):4494-502.
2009: W Marston Linehan; Peter A Pinto; Gennady Bratslavsky; Elizabeth Pfaffenroth; Maria Merino; Cathy D Vocke; Jorge R Toro; Donald Bottaro; Len Neckers; Laura S Schmidt; Ramaprasad Srinivasan
Hereditary kidney cancer: unique opportunity for disease-based therapy.
Cancer 2009;115(10 Suppl):2252-61.
2009: Gulsun Erdag; Jeanne M Meck; Aurelia Meloni-Ehrig; Ludmila Matyakhina; Theresa Donohue; Ramaprasad Srinivasan; Philip Mowrey; JoAnn Kelly; Aleah Smith; Richard Childs
Long-term persistence of nonpathogenic clonal chromosome abnormalities in donor hematopoietic cells after allogeneic stem cell transplantation.
Cancer genetics and cytogenetics 2009;190(2):125-30.
2008: Yoshiyuki Takahashi; Nanae Harashima; Sachiko Kajigaya; Hisayuki Yokoyama; Elena Cherkasova; J Philip McCoy; Ken-Ichi Hanada; Othon Mena; Roger Kurlander; Abdul Tawab; Tawab Abdul; Ramaprasad Srinivasan; Andreas Lundqvist; Elizabeth Malinzak; Nancy Geller; Michael I Lerman; Richard W Childs
Regression of human kidney cancer following allogeneic stem cell transplantation is associated with recognition of an HERV-E antigen by T cells.
The Journal of clinical investigation 2008;118(3):1099-109.
2007: Bipin N Savani; Stephan Mielke; S Adams; M Uribe; Katayoun Rezvani; Agnes S M Yong; J Zeilah; Roger Kurlander; Ramaprasad Srinivasan; Richard Childs; Nancy Hensel; A John Barrett
Rapid natural killer cell recovery determines outcome after T-cell-depleted HLA-identical stem cell transplantation in patients with myeloid leukemias but not with acute lymphoblastic leukemia.
Leukemia 2007;21(10):2145-52.
2007: Robert L Grubb; Michael E Franks; Jorge Toro; Lindsay Middelton; Lynda Choyke; Sarah Fowler; Carlos Torres-Cabala; Gladys Glenn; Peter Choyke; Maria J Merino; Berton Zbar; Peter A Pinto; Ramaprasad Srinivasan; Jonathan Coleman; W Marston Linehan
Hereditary leiomyomatosis and renal cell cancer: a syndrome associated with an aggressive form of inherited renal cancer.
The Journal of urology 2007;177(6):2074-9; discussion 2079-80.
2007: Ramaprasad Srinivasan; Andrew J Armstrong; William Dahut; Daniel J George
Anti-angiogenic therapy in renal cell cancer.
BJU international 2007;99(5 Pt B):1296-300.
2007: Ramaprasad Srinivasan; W Marston Linehan
Antiangiogenic therapy in renal cell carcinoma: from concept to reality.
Nature clinical practice. Urology 2007;4(2):74-5.
2007: W Marston Linehan; Peter A Pinto; Ramaprasad Srinivasan; Maria Merino; Peter Choyke; Lynda Choyke; Jonathan Coleman; Jorge Toro; Gladys Glenn; Cathy D Vocke; Berton Zbar; Laura S Schmidt; Donald Bottaro; Len Neckers
Identification of the genes for kidney cancer: opportunity for disease-specific targeted therapeutics.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(2 Pt 2):671s-679s.
2006: Bipin N Savani; Aldemar Montero; Ramaprasad Srinivasan; anurag singh; Aarthi Shenoy; Stephan Mielke; Katayoun Rezvani; Shervin Karimpour; Richard Childs; A John Barrett
Chronic GVHD and pretransplantation abnormalities in pulmonary function are the main determinants predicting worsening pulmonary function in long-term survivors after stem cell transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2006;12(12):1261-9.
2006: Jean-Baptiste Lattouf; Ramaprasad Srinivasan; Peter A Pinto; W Marston Linehan; Len Neckers
Mechanisms of disease: the role of heat-shock protein 90 in genitourinary malignancy.
Nature clinical practice. Urology 2006;3(11):590-601.
2006: Anne Rothman; Gladys Glenn; Lynda Choyke; Ramaprasad Srinivasan; W Marston Linehan; Edward W Cowen
Multiple painful cutaneous nodules and renal mass.
Journal of the American Academy of Dermatology 2006;55(4):683-6.
2006: Ramaprasad Srinivasan; Jasmine Daniels; Vincent Fusaro; Andreas Lundqvist; J Keith Killian; David H Geho; Martha Quezado; David Kleiner; Sally Rucker; Virginia Espina; Gordon R Whiteley; Lance A Liotta; Emanuel F Petricoin; Stefania Pittaluga; Ben Hitt; A John Barrett; Kevin P Rosenblatt; Richard W Childs
Accurate diagnosis of acute graft-versus-host disease using serum proteomic pattern analysis.
Experimental hematology 2006;34(6):796-801.
2006: Ramaprasad Srinivasan; Yoshiyuki Takahashi; J Philip McCoy; Igor Espinoza-Delgado; Colleen Dorrance; Takehito Igarashi; Andreas Lundqvist; A John Barrett; Neal S Young; Nancy Geller; Richard W Childs
Overcoming graft rejection in heavily transfused and allo-immunised patients with bone marrow failure syndromes using fludarabine-based haematopoietic cell transplantation.
British journal of haematology 2006;133(3):305-14.
2005: Bipin N Savani; Ramaprasad Srinivasan; Igor Espinoza-Delgado; Colleen Dorrance; Yoshiyuki Takahashi; Takehito Igarashi; Katayoun Rezvani; Andreas Lundqvist; A John Barrett; Richard W Childs
Treatment of relapsed blast-phase Philadelphia-chromosome-positive leukaemia after non-myeloablative stem-cell transplantation with donor lymphocytes and imatinib.
The lancet oncology 2005;6(10):809-12.
2005: Ramaprasad Srinivasan; James E Balow; Sharda G Sabnis; Andreas Lundqvist; Takehito Igarashi; Yoshiyuki Takahashi; Howard A Austin; John F Tisdale; John Barrett; Nancy Geller; Richard Childs
Nephrotic syndrome: an under-recognised immune-mediated complication of non-myeloablative allogeneic haematopoietic cell transplantation.
British journal of haematology 2005;131(1):74-9.
2005: Richard Childs; Ramaprasad Srinivasan
High-dose chemotherapy and allogeneic immunotherapy.
Lancet 2005;366(9482):273-5.
2005: Edward Gorak; Nancy Geller; Ramaprasad Srinivasan; Igor Espinoza-Delgado; Theresa Donohue; A John Barrett; Anthony Suffredini; Richard Childs
Engraftment syndrome after nonmyeloablative allogeneic hematopoietic stem cell transplantation: incidence and effects on survival.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2005;11(7):542-50.
2005: Ramaprasad Srinivasan; Armando C Filie; James Reynolds; Richard Chang; Catherine Chow; David S Schrump; Yoshiyuki Takahashi; Anthony F Suffredini; Richard W Childs
Positron emission tomography for lymphoma staging: tissue remains the issue.
Journal of the National Cancer Institute 2005;97(8):611-3.
2005: Linda M Griffith; J Philip McCoy; Charles D Bolan; David F Stroncek; A C Pickett; Gilda F Linton; Andreas Lundqvist; Ramaprasad Srinivasan; Susan F Leitman; Richard W Childs
Persistence of recipient plasma cells and anti-donor isohaemagglutinins in patients with delayed donor erythropoiesis after major ABO incompatible non-myeloablative haematopoietic cell transplantation.
British journal of haematology 2005;128(5):668-75.
2005: Ramaprasad Srinivasan; W Marston Linehan
Targeted for destruction: the molecular basis for development of novel therapeutic strategies in renal cell cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(3):410-2.
2004: W Marston Linehan; James R Vasselli; Ramaprasad Srinivasan; McClellan Walther; Maria Merino; Peter Choyke; Cathy D Vocke; Laura Schmidt; Jennifer S. Isaacs; Gladys Glenn; Jorge Toro; Berton Zbar; Donald Bottaro; Len Neckers
Genetic basis of cancer of the kidney: disease-specific approaches to therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(18 Pt 2):6282S-9S.
2004: Ramaprasad Srinivasan; S Chakrabarti; THOMAS WALSH; Takehito Igarashi; Yoshiyuki Takahashi; David Kleiner; Theresa Donohue; R Shalabi; Cristian Carvallo; A John Barrett; Nancy Geller; Richard Childs
Improved survival in steroid-refractory acute graft versus host disease after non-myeloablative allogeneic transplantation using a daclizumab-based strategy with comprehensive infection prophylaxis.
British journal of haematology 2004;124(6):777-86.
2004: Cristian Carvallo; Nancy Geller; Roger Kurlander; Ramaprasad Srinivasan; Othon Mena; Takehito Igarashi; Linda M Griffith; W Marston Linehan; Richard W Childs
Prior chemotherapy and allograft CD34+ dose impact donor engraftment following nonmyeloablative allogeneic stem cell transplantation in patients with solid tumors.
Blood 2004;103(4):1560-3.
2004: Yoshiyuki Takahashi; J Philip McCoy; Cristian Carvallo; Candido Rivera; Takehito Igarashi; Ramaprasad Srinivasan; Neal S Young; Richard W Childs
In vitro and in vivo evidence of PNH cell sensitivity to immune attack after nonmyeloablative allogeneic hematopoietic cell transplantation.
Blood 2004;103(4):1383-90.
2004: Francesca Re; Ramaprasad Srinivasan; Takehito Igarashi; Franco Marincola; Richard Childs
Green fluorescent protein expression in dendritic cells enhances their immunogenicity and elicits specific cytotoxic T-cell responses in humans.
Experimental hematology 2004;32(2):210-7.