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William St Clair

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E William St Clair; Frederick B Vivino; Josiah Wedgwood; Chacko J Alappatt; Philip Cohen; Lytia Fisher; Marc C Levesque; James McNamara; Kathy L Moser Sivils; Eline T Luning Prak; Meagan E Spychala
Rituximab therapy for primary Sjögren's syndrome: an open-label clinical trial and mechanistic analysis.
Mala S Kaul; Sunil V Rao; Linda K Shaw; Stacy P Ardoin; Emily Honeycutt; E William St Clair
Association of systemic lupus erythematosus with angiographically defined coronary artery disease: a retrospective cohort study.
Sharon A Chung; Paul F Dellaripa; Jeffrey C Edberg; Gary S Hoffman; Megan Kravitz; Alfred D Mahr; Peter A Merkel; Robert M Plenge; Delnaz Roshandel; Philip Seo; Richard Sherva; Katherine A Siminovitch; Ulrich Specks; Robert Spiera; E William St Clair; John H Stone; Gang Xie; Paul A Monach
Meta-analysis of genetic polymorphisms in granulomatosis with polyangiitis (Wegener's) reveals shared susceptibility loci with rheumatoid arthritis.

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2013: E William St Clair; Frederick B Vivino; Josiah Wedgwood; Chacko J Alappatt; Philip Cohen; Lytia Fisher; Marc C Levesque; James McNamara; Kathy L Moser Sivils; Eline T Luning Prak; Meagan E Spychala
Rituximab therapy for primary Sjögren's syndrome: an open-label clinical trial and mechanistic analysis.
Arthritis and rheumatism 2013;65(4):1097-106.
2013: Mala S Kaul; Sunil V Rao; Linda K Shaw; Stacy P Ardoin; Emily Honeycutt; E William St Clair
Association of systemic lupus erythematosus with angiographically defined coronary artery disease: a retrospective cohort study.
Arthritis care & research 2013;65(2):266-73.
2012: Sharon A Chung; Paul F Dellaripa; Jeffrey C Edberg; Gary S Hoffman; Megan Kravitz; Alfred D Mahr; Peter A Merkel; Robert M Plenge; Delnaz Roshandel; Philip Seo; Richard Sherva; Katherine A Siminovitch; Ulrich Specks; Robert Spiera; E William St Clair; John H Stone; Gang Xie; Paul A Monach
Meta-analysis of genetic polymorphisms in granulomatosis with polyangiitis (Wegener's) reveals shared susceptibility loci with rheumatoid arthritis.
Arthritis and rheumatism 2012;64(10):3463-71.
2012: E William St Clair
Hepatitis C virus-related cryoglobulinemic vasculitis: emerging trends in therapy.
Arthritis and rheumatism 2012;64(3):604-8.
2012: Gunnar Tomasson; Michael Walsh; Steven R Ytterberg; Paul A Monach; Philip Seo; Ulrich Specks; Robert Spiera; E William St Clair; John H Stone; Maarten Boers; Simon Carette; David Cuthbertson; John C Davis; Gary S Hoffman; Nader A Khalidi; Carol A Langford; Michael P LaValley; Carol A McAlear; W Joseph McCune; Peter A Merkel
Assessment of health-related quality of life as an outcome measure in granulomatosis with polyangiitis (Wegener's).
Arthritis care & research 2012;64(2):273-9.
2012: Paul A Monach; Philip Seo; Ulrich Specks; Robert Spiera; E William St Clair; John H Stone; Nadia Tchao; Gunnar Tomasson; Steven R Ytterberg; Simon Carette; David Cuthbertson; Linna Ding; Marion Haubitz; Gary S Hoffman; David Iklé; Cees G M Kallenberg; Nader A Khalidi; Jeffrey Krischer; Philipp Kümpers; Carol A Langford; Alexander Lukasz; Peter A Merkel
Circulating angiopoietin-2 as a biomarker in ANCA-associated vasculitis.
PloS one 2012;7(1):e30197.
2011: Megan E B Clowse; Susannah C Copland; John C Davis; Gary S Hoffman; Tsung-Cheng Hsieh; W Joseph McCune; Peter A Merkel; Ulrich Specks; Robert F Spiera; E William St Clair; John H Stone; Steven R Ytterberg; Nancy B Allen; Shein-Chung Chow
Ovarian reserve diminished by oral cyclophosphamide therapy for granulomatosis with polyangiitis (Wegener's).
Arthritis care & research 2011;63(12):1777-81.
2011: Paul A Monach; Mark Mueller; Philip Seo; Ronald D Snyder; Ulrich Specks; Robert Spiera; E William St Clair; John H Stone; Nadia Tchao; Gunnar Tomasson; Steven R Ytterberg; David Cuthbertson; Linna Ding; Fernando C Fervenza; Barri J Fessler; Yi-Zhong Gu; Gary S Hoffman; David Ikle; Cees G M Kallenberg; Jeffrey Krischer; Carol A Langford; Peter A Merkel
Circulating markers of vascular injury and angiogenesis in antineutrophil cytoplasmic antibody-associated vasculitis.
Arthritis and rheumatism 2011;63(12):3988-97.
2011: Gunnar Tomasson; John C Davis; Javier D Finkielman; Jane E Freedman; Gary S Hoffman; Michael P LaValley; W Joseph McCune; Peter A Merkel; Ulrich Specks; Robert Spiera; E William St Clair; John H Stone; Kahraman Tanriverdi
Relationship between markers of platelet activation and inflammation with disease activity in Wegener's granulomatosis.
The Journal of rheumatology 2011;38(6):1048-54.
2011: Yohei Iwata; Takashi Matsushita; Mayuka Horikawa; David J DiLillo; Koichi Yanaba; Guglielmo M Venturi; Paul M Szabolcs; Steven H Bernstein; Cynthia M Magro; Armistead D Williams; Russell P Hall; E William St Clair; Thomas F Tedder
Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells.
Blood 2011;117(2):530-41.
2010: Alfred Mahr; Jeffrey C Edberg; John H Stone; Gary S Hoffman; E William St Clair; Ulrich Specks; Paul F Dellaripa; Philip Seo; Robert Spiera; Farshid N Rouhani; Mark L Brantly; Peter A Merkel
Alpha₁-antitrypsin deficiency-related alleles Z and S and the risk of Wegener's granulomatosis.
Arthritis and rheumatism 2010;62(12):3760-7.
2010: E William St Clair
Good and bad memories following rituximab therapy.
Arthritis and rheumatism 2010;62(1):1-5.
2009: E William St Clair
Novel targeted therapies for autoimmunity.
Current opinion in immunology 2009;21(6):648-57.
2009: Josef S Smolen; Désirée van der Heijde; Daniel Aletaha; S Xu; J Han; D Baker; E William St Clair
Progression of radiographic joint damage in rheumatoid arthritis: independence of erosions and joint space narrowing.
Annals of the rheumatic diseases 2009;68(10):1535-40.
2009: Josef S Smolen; C Han; D M F M van der Heijde; P Emery; Joan M Bathon; Edward Keystone; Ravinder N Maini; Joachim R Kalden; Daniel Aletaha; D Baker; J Han; M Bala; E William St Clair
Radiographic changes in rheumatoid arthritis patients attaining different disease activity states with methotrexate monotherapy and infliximab plus methotrexate: the impacts of remission and tumour necrosis factor blockade.
Annals of the rheumatic diseases 2009;68(6):823-7.
2009: Javier D Finkielman; Peter A Merkel; D Schroeder; Gary S Hoffman; Robert Spiera; E William St Clair; John C Davis; W Joseph McCune; A Lears; Steven R Ytterberg; Amber M Hummel; Margaret A Viss; Tobias Peikert; John H Stone; Ulrich Specks
Glycosylation of proteinase 3 (PR3) is not required for its reactivity with antineutrophil cytoplasmic antibodies (ANCA) in Wegener's granulomatosis.
Clinical and experimental rheumatology 2009;27(1 Suppl 52):S45-52.
2008: Alfred Mahr; Tuhina Neogi; Michael P LaValley; John C Davis; Gary S Hoffman; W Joseph McCune; Ulrich Specks; Robert Spiera; E William St Clair; John H Stone; Peter A Merkel
Assessment of the item selection and weighting in the Birmingham vasculitis activity score for Wegener's granulomatosis.
Arthritis and rheumatism 2008;59(6):884-91.
2008: Koichi Yanaba; Jean-David Bouaziz; Takashi Matsushita; Cynthia M Magro; E William St Clair; Thomas F Tedder
B-lymphocyte contributions to human autoimmune disease.
Immunological reviews 2008;223():284-99.
2008: Peter K Wung; Troy Anderson; Kevin R Fontaine; Gary S Hoffman; Ulrich Specks; Peter A Merkel; Robert Spiera; John C Davis; E William St Clair; W Joseph McCune; John H Stone
Effects of glucocorticoids on weight change during the treatment of Wegener's granulomatosis.
Arthritis and rheumatism 2008;59(5):746-53.
2008: E William St Clair
The calm after the cytokine storm: lessons from the TGN1412 trial.
The Journal of clinical investigation 2008;118(4):1344-7.
2008: Marc C Levesque; E William St Clair
B cell-directed therapies for autoimmune disease and correlates of disease response and relapse.
The Journal of allergy and clinical immunology 2008;121(1):13-21; quiz 22-3.
2007: Jodi K Sebastian; Barbara Voetsch; John H Stone; Zurina Romay-Penabad; Grace H Lo; Nancy B Allen; John C Davis; Gary S Hoffman; W Joseph McCune; E William St Clair; Ulrich Specks; Robert Spiera; Joseph Loscalzo; Silvia S Pierangeli; Peter A Merkel
The frequency of anticardiolipin antibodies and genetic mutations associated with hypercoagulability among patients with Wegener's granulomatosis with and without history of a thrombotic event.
The Journal of rheumatology 2007;34(12):2446-50.
2007: Javier D Finkielman; Peter A Merkel; Darrell Schroeder; Gary S Hoffman; Robert Spiera; E William St Clair; John C Davis; W Joseph McCune; Andrea K Lears; Steven R Ytterberg; Amber M Hummel; Margaret A Viss; Tobias Peikert; John H Stone; Ulrich Specks
Antiproteinase 3 antineutrophil cytoplasmic antibodies and disease activity in Wegener granulomatosis.
Annals of internal medicine 2007;147(9):611-9.
2007: Chenglong Han; Mahboob U Rahman; Mittie K Doyle; Joan M Bathon; Josef Smolen; Arthur Kavanaugh; René Westhovens; E William St Clair; Daniel Baker; Mohan Bala
Association of anemia and physical disability among patients with rheumatoid arthritis.
The Journal of rheumatology 2007;34(11):2177-82.
2007: Koichi Yanaba; Yasuhito Hamaguchi; Guglielmo M Venturi; Douglas A Steeber; E William St Clair; Thomas F Tedder
B cell depletion delays collagen-induced arthritis in mice: arthritis induction requires synergy between humoral and cell-mediated immunity.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(2):1369-80.
2007: Javier D Finkielman; Augustine S Lee; Amber M Hummel; Margaret A Viss; Gregory L Jacob; Henry A Homburger; Tobias Peikert; Gary S Hoffman; Peter A Merkel; Robert Spiera; E William St Clair; John C Davis; W Joseph McCune; Andrea K Tibbs; Steven R Ytterberg; John H Stone; Ulrich Specks
ANCA are detectable in nearly all patients with active severe Wegener's granulomatosis.
The American journal of medicine 2007;120(7):643.e9-14.
2007: R John Looney; Betty Diamond; V Michael Holers; Marc C Levesque; Larry Moreland; Moon H Nahm; E William St Clair
Guidelines for assessing immunocompetency in clinical trials for autoimmune diseases.
Clinical immunology (Orlando, Fla.) 2007;123(3):235-43.
2007: Jodi K Sebastian; Alfred Mahr; Sohail S Ahmed; John H Stone; Zurina Romay-Penabad; John C Davis; Gary S Hoffman; W Joseph McCune; E William St Clair; Ulrich Specks; Robert Spiera; Silvia S Pierangeli; Peter A Merkel
Antiendothelial cell antibodies in patients with Wegener's granulomatosis: prevalence and correlation with disease activity and manifestations.
The Journal of rheumatology 2007;34(5):1027-31.
2007: E William St Clair; Larry A Turka; Andrew Saxon; Jeffrey B Matthews; Mohamed H Sayegh; George S Eisenbarth; Jeffrey Bluestone
New reagents on the horizon for immune tolerance.
Annual review of medicine 2007;58():329-46.
2006: John H Stone; Janet T Holbrook; Matthew A Marriott; Andrea K Tibbs; Lourdes P Sejismundo; Yuan-I Min; Ulrich Specks; Peter A Merkel; Robert Spiera; John C Davis; E William St Clair; W Joseph McCune; Steven R Ytterberg; Nancy B Allen; Gary S Hoffman
Solid malignancies among patients in the Wegener's Granulomatosis Etanercept Trial.
Arthritis and rheumatism 2006;54(5):1608-18.
2006: Josef S Smolen; Chenglong Han; Désirée van der Heijde; Paul Emery; Joan M Bathon; Edward Keystone; Joachim R Kalden; Michael Schiff; Mohan Bala; Daniel Baker; John Han; Ravinder N Maini; E William St Clair
Infliximab treatment maintains employability in patients with early rheumatoid arthritis.
Arthritis and rheumatism 2006;54(3):716-22.
2006: Josef S Smolen; Désirée van der Heijde; E William St Clair; Paul Emery; Joan M Bathon; Edward Keystone; Ravinder N Maini; Joachim R Kalden; Michael Schiff; Daniel Baker; Chenglong Han; John Han; Mohan Bala
Predictors of joint damage in patients with early rheumatoid arthritis treated with high-dose methotrexate with or without concomitant infliximab: results from the ASPIRE trial.
Arthritis and rheumatism 2006;54(3):702-10.
2006: Christine Savage; E William St Clair
New therapeutics in rheumatoid arthritis.
Rheumatic diseases clinics of North America 2006;32(1):57-74, viii.
2006: J Brice Weinberg; Thomas Lang; William E Wilkinson; David S Pisetsky; E William St Clair
Serum, urinary, and salivary nitric oxide in rheumatoid arthritis: complexities of interpreting nitric oxide measures.
Arthritis research & therapy 2006;8(5):R140.
2005: Peter K Wung; Janet T Holbrook; Gary S Hoffman; Andrea K Tibbs; Ulrich Specks; Yuan-I Min; Peter A Merkel; Robert Spiera; John C Davis; E William St Clair; Joseph M McCune; Steven R Ytterberg; Nancy B Allen; John H Stone
Herpes zoster in immunocompromised patients: incidence, timing, and risk factors.
The American journal of medicine 2005;118(12):1416.
2005: Philip Seo; Yuan-I Min; Janet T Holbrook; Gary S Hoffman; Peter A Merkel; Robert Spiera; John C Davis; Steven R Ytterberg; E William St Clair; W Joseph McCune; Ulrich Specks; Nancy B Allen; Raashid Luqmani; John H Stone
Damage caused by Wegener's granulomatosis and its treatment: prospective data from the Wegener's Granulomatosis Etanercept Trial (WGET).
Arthritis and rheumatism 2005;52(7):2168-78.
2005: Barton F Haynes; Judith Fleming; E William St Clair; Hermann Katinger; Gabriela Stiegler; Renate Kunert; James Robinson; Richard M Scearce; Kelly Plonk; Herman F Staats; Thomas L Ortel; Hua-Xin Liao; S Munir Alam
Cardiolipin polyspecific autoreactivity in two broadly neutralizing HIV-1 antibodies.
Science (New York, N.Y.) 2005;308(5730):1906-8.
2005: Peter A Merkel; Grace H Lo; Janet T Holbrook; Andrea K Tibbs; Nancy B Allen; John C Davis; Gary S Hoffman; W Joseph McCune; E William St Clair; Ulrich Specks; Robert Spiera; Michelle Petri; John H Stone
Brief communication: high incidence of venous thrombotic events among patients with Wegener granulomatosis: the Wegener's Clinical Occurrence of Thrombosis (WeCLOT) Study.
Annals of internal medicine 2005;142(8):620-6.
2005: Robin C Geletka; E William St Clair
Infliximab for the treatment of early rheumatoid arthritis.
Expert opinion on biological therapy 2005;5(3):405-17.
2005: John H Stone; Vinodh N Rajapakse; Gary S Hoffman; Ulrich Specks; Peter A Merkel; Robert Spiera; John C Davis; E William St Clair; Joseph M McCune; Sally Ross; Ben A Hitt; Timothy D Veenstra; Thomas P Conrads; Lance A Liotta; Emanuel F Petricoin
A serum proteomic approach to gauging the state of remission in Wegener's granulomatosis.
Arthritis and rheumatism 2005;52(3):902-10.
2004: E William St Clair; Désirée van der Heijde; Josef S Smolen; Ravinder N Maini; Joan M Bathon; Paul Emery; Edward Keystone; Michael Schiff; Joachim R Kalden; Ben Wang; Kimberly Dewoody; Roberta Weiss; Daniel Baker
Combination of infliximab and methotrexate therapy for early rheumatoid arthritis: a randomized, controlled trial.
Arthritis and rheumatism 2004;50(11):3432-43.
2004: Ravinder N Maini; F C Breedveld; Joachim R Kalden; J S Smolen; D Furst; M H Weisman; E William St Clair; Gregory F Keenan; Désirée van der Heijde; PA Marsters; P E Lipsky
Sustained improvement over two years in physical function, structural damage, and signs and symptoms among patients with rheumatoid arthritis treated with infliximab and methotrexate.
Arthritis and rheumatism 2004;50(4):1051-65.
2003: Robin Geletka; E William St Clair
Treatment of early rheumatoid arthritis.
Best practice & research. Clinical rheumatology 2003;17(5):791-809.
2003: Lisa G Criscione; Jeremy Sugarman; Linda Sanders; David S Pisetsky; E William St Clair
Informed consent in a clinical trial of a novel treatment for rheumatoid arthritis.
Arthritis and rheumatism 2003;49(3):361-7.
2002: E William St Clair; Carrie L Wagner; Adedigbo A Fasanmade; Benjamin Wang; Thomas Schaible; Arthur Kavanaugh; Edward Keystone
The relationship of serum infliximab concentrations to clinical improvement in rheumatoid arthritis: results from ATTRACT, a multicenter, randomized, double-blind, placebo-controlled trial.
Arthritis and rheumatism 2002;46(6):1451-9.
2001: E William St Clair; William E Wilkinson; David S Pisetsky; Daniel J Sexton; R Drew; Virginia B Kraus; Robert Greenwald
The effects of intravenous doxycycline therapy for rheumatoid arthritis: a randomized, double-blind, placebo-controlled trial.
Arthritis and rheumatism 2001;44(5):1043-7.
2001: John H Stone; Gary S Hoffman; Peter A Merkel; Yuan-I Min; Misty L Uhlfelder; David B Hellmann; Ulrich Specks; Nancy B Allen; John C Davis; Robert Spiera; L H Calabrese; Fredrick M Wigley; N Maiden; R M Valente; John L Niles; Kenneth H Fye; W Joseph McCune; E William St Clair; Raashid Luqmani
A disease-specific activity index for Wegener's granulomatosis: modification of the Birmingham Vasculitis Activity Score. International Network for the Study of the Systemic Vasculitides (INSSYS).
Arthritis and rheumatism 2001;44(4):912-20.
2000: Peter E Lipsky; D M van der Heijde; E William St Clair; D E Furst; F C Breedveld; J R Kalden; J S Smolen; Michael Weisman; P Emery; M Feldmann; G R Harriman; R N Maini
Infliximab and methotrexate in the treatment of rheumatoid arthritis. Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group.
The New England journal of medicine 2000;343(22):1594-602.
2000: E William St Clair; S B Cohen; M L Lee; R M Fleischmann; S H Lee; Larry W Moreland; N J Olsen; P W Pratt; D E Yocum; Louis W Heck; J Winkelhake; J S Holcenberg; M J Shulman
Treatment of rheumatoid arthritis with a DR4/1 peptide.
The Journal of rheumatology 2000;27(8):1855-63.
2000: Marc C Levesque; D A Mackin; J A Fleming; E William St Clair
Serum levels of soluble CD44 in primary Sjögren's syndrome.
The Journal of rheumatology 2000;27(6):1444-9.
2000: Arthur Kavanaugh; E William St Clair; W Joseph McCune; T Braakman; Peter E Lipsky
Chimeric anti-tumor necrosis factor-alpha monoclonal antibody treatment of patients with rheumatoid arthritis receiving methotrexate therapy.
The Journal of rheumatology 2000;27(4):841-50.
1999: H James Williams; G S Alarcon; R Joks; Virginia Steen; K Bulpitt; Daniel O Clegg; CAROL ZIMINSKI; M E Luggen; E William St Clair; RF Willkens; C Yarboro; JG Morgan; MJ Egger; J R Ward
Early undifferentiated connective tissue disease (CTD). VI. An inception cohort after 10 years: disease remissions and changes in diagnoses in well established and undifferentiated CTD.
The Journal of rheumatology 1999;26(4):816-25.
1998: E William St Clair; SA Moak; William E Wilkinson; L Sanders; T Lang; Robert Greenwald
A cross sectional analysis of 5 different markers of collagen degradation in rheumatoid arthritis.
The Journal of rheumatology 1998;25(8):1472-9.
1998: M L Barnett; Joel M Kremer; E William St Clair; Daniel O Clegg; Daniel E Furst; Michael Weisman; M J Fletcher; S Chasan-Taber; E Finger; A Morales; CH Le; DE Trentham
Treatment of rheumatoid arthritis with oral type II collagen. Results of a multicenter, double-blind, placebo-controlled trial.
Arthritis and rheumatism 1998;41(2):290-7.
1997: Joel M Kremer; Graciela S Alarcón; Michael E Weinblatt; M V Kaymakcian; M Macaluso; Grant W Cannon; W R Palmer; J S Sundy; E William St Clair; R W Alexander; G J Smith; C A Axiotis
Clinical, laboratory, radiographic, and histopathologic features of methotrexate-associated lung injury in patients with rheumatoid arthritis: a multicenter study with literature review.
Arthritis and rheumatism 1997;40(10):1829-37.
1997: Graciela S Alarcón; Joel M Kremer; M Macaluso; Michael E Weinblatt; Grant W Cannon; W R Palmer; E William St Clair; J S Sundy; R W Alexander; G J Smith; C A Axiotis
Risk factors for methotrexate-induced lung injury in patients with rheumatoid arthritis. A multicenter, case-control study. Methotrexate-Lung Study Group.
Annals of internal medicine 1997;127(5):356-64.
1996: Nancy J Olsen; RH Brooks; J J Cush; P E Lipsky; E William St Clair; Eric L Matteson; K N Gold; Grant W Cannon; C G Jackson; W Joseph McCune; David A Fox; B Nelson; T Lorenz; V Strand
A double-blind, placebo-controlled study of anti-CD5 immunoconjugate in patients with rheumatoid arthritis. The Xoma RA Investigator Group.
Arthritis and rheumatism 1996;39(7):1102-8.
1996: J D Isaacs; V K Manna; N Rapson; Ken J Bulpitt; B L Hazleman; Eric L Matteson; E William St Clair; T J Schnitzer; J M Johnston
CAMPATH-1H in rheumatoid arthritis--an intravenous dose-ranging study.
British journal of rheumatology 1996;35(3):231-40.
1995: Eric L Matteson; D E Yocum; E William St Clair; A A Achkar; M S Thakor; M R Jacobs; A E Hays; C K Heitman; J M Johnston
Treatment of active refractory rheumatoid arthritis with humanized monoclonal antibody CAMPATH-1H administered by daily subcutaneous injection.
Arthritis and rheumatism 1995;38(9):1187-93.