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Hinrich Staecker

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Anatomy

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Sensorineural Hearing Loss

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Hinrich Staecker; Brian Rodgers
Developments in delivery of medications for inner ear disease.
Shannon Kraft; Douglas E Brough; Chi Hsu; Hinrich Staecker
Atoh1 induces auditory hair cell recovery in mice after ototoxic injury.
Keerthana Devarajan; M Laird Forrest; Michael S Detamore; Hinrich Staecker
Adenovector-mediated gene delivery to human umbilical cord mesenchymal stromal cells induces inner ear cell phenotype.

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All Publications

2013: Hinrich Staecker; Brian Rodgers
Developments in delivery of medications for inner ear disease.
Expert opinion on drug delivery 2013;10(5):639-50.
2013: Shannon Kraft; Douglas E Brough; Chi Hsu; Hinrich Staecker
Atoh1 induces auditory hair cell recovery in mice after ototoxic injury.
The Laryngoscope 2013;123(4):992-9.
2013: Keerthana Devarajan; M Laird Forrest; Michael S Detamore; Hinrich Staecker
Adenovector-mediated gene delivery to human umbilical cord mesenchymal stromal cells induces inner ear cell phenotype.
Cellular reprogramming 2013;15(1):43-54.
2013: Aritra Bhattacherjee; M A Karim Rumi; Hinrich Staecker; Peter G Smith
Bone morphogenetic protein 4 mediates estrogen-regulated sensory axon plasticity in the adult female reproductive tract.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2013;33(3):1050-61a.
2012: Kim Baker; Hinrich Staecker
Low dose oxidative stress induces mitochondrial damage in hair cells.
Anatomical record (Hoboken, N.J. : 2007) 2012;295(11):1868-76.
2012: Davina Gassner; Susanna C Pfannenstiel; Douglas E Brough; Dianne Durham; Hinrich Staecker
Canalostomy as a surgical approach for cochlear gene therapy in the rat.
Anatomical record (Hoboken, N.J. : 2007) 2012;295(11):1830-6.
2012: Sébastien Barriat; Hinrich Staecker; France van Wijck; Philippe P Lefebvre
Intratympanic steroid therapy using the Silverstein Microwick™ for refractory sudden sensorineural hearing loss increases speech intelligibility.
Audiology & neuro-otology 2012;17(2):105-11.
2011: Hinrich Staecker; Mark Praetorius; Douglas E Brough
Development of gene therapy for inner ear disease: Using bilateral vestibular hypofunction as a vehicle for translational research.
Hearing research 2011;276(1-2):44-51.
2010: Hinrich Staecker; Carolyn Garnham
Neurotrophin therapy and cochlear implantation: translating animal models to human therapy.
Experimental neurology 2010;226(1):1-5.
2010: Hinrich Staecker; Claude Jolly; Carolyn Garnham
Cochlear implantation: an opportunity for drug development.
Drug discovery today 2010;15(7-8):314-21.
2010: Sandra Prentiss; Kevin Sykes; Hinrich Staecker
Partial deafness cochlear implantation at the University of Kansas: techniques and outcomes.
Journal of the American Academy of Audiology 2010;21(3):197-203.
2010: Mark Praetorius; Chi Hsu; Kim Baker; Douglas E Brough; Peter K Plinkert; Hinrich Staecker
Adenovector-mediated hair cell regeneration is affected by promoter type.
Acta oto-laryngologica 2010;130(2):215-22.
2009: Mark Praetorius; Hinrich Staecker; P K Plinkert
[Surgical technique in cochlear implantation].
HNO 2009;57(7):663-70.
2009: Mark Praetorius; Douglas E Brough; Chi Hsu; Peter K Plinkert; Susanna C Pfannenstiel; Hinrich Staecker
Adenoviral vectors for improved gene delivery to the inner ear.
Hearing research 2009;248(1-2):31-8.
2009: Kim Baker; Douglas E Brough; Hinrich Staecker
Repair of the vestibular system via adenovector delivery of Atoh1: a potential treatment for balance disorders.
Advances in oto-rhino-laryngology 2009;66():52-63.
2009: Susanna C Pfannenstiel; Mark Praetorius; Peter K Plinkert; Douglas E Brough; Hinrich Staecker
Bcl-2 gene therapy prevents aminoglycoside-induced degeneration of auditory and vestibular hair cells.
Audiology & neuro-otology 2009;14(4):254-66.
2008: James Lin; Hinrich Staecker; M Samir Jafri
Optical coherence tomography imaging of the inner ear: a feasibility study with implications for cochlear implantation.
The Annals of otology, rhinology, and laryngology 2008;117(5):341-6.
2008: Mark Praetorius; S Pfannenstiel; C Klingmann; I Baumann; P K Plinkert; Hinrich Staecker
[Expression patterns of non-viral transfection with GFP in the organ of Corti in vitro and in vivo. Gene therapy of the inner ear with non-viral vectors].
HNO 2008;56(5):524-9.
2007: France Van Wijck; Hinrich Staecker; Philippe P Lefebvre
Topical steroid therapy using the Silverstein Microwick in sudden sensorineural hearing loss after failure of conventional treatment.
Acta oto-laryngologica 2007;127(10):1012-7.
2007: Mark Praetorius; Christian Brunner; Bernhard Lehnert; Christoph Klingmann; Helmut Schmidt; Hinrich Staecker; Bernhard Schick
Transsynaptic delivery of nanoparticles to the central auditory nervous system.
Acta oto-laryngologica 2007;127(5):486-90.
2007: Mark Praetorius; Kim Baker; Douglas E Brough; Peter K Plinkert; Hinrich Staecker
Pharmacodynamics of adenovector distribution within the inner ear tissues of the mouse.
Hearing research 2007;227(1-2):53-8.
2007: Hinrich Staecker; Mark Praetorius; Kim Baker; Douglas E Brough
Vestibular hair cell regeneration and restoration of balance function induced by math1 gene transfer.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 2007;28(2):223-31.
2007: J Ursick; Hinrich Staecker
An overview of animal models of tinnitus.
B-ENT 2007;3 Suppl 7():23-5.
2007: Hinrich Staecker; Wei Liu; Brigitte Malgrange; Philippe P Lefebvre; Thomas R Van De Water
Vector-mediated delivery of bcl-2 prevents degeneration of auditory hair cells and neurons after injury.
ORL; journal for oto-rhino-laryngology and its related specialties 2007;69(1):43-50.
2006: Mark Praetorius; Hinrich Staecker
[ASA and the inner ear. An old acquaintance in a new light].
HNO 2006;54(9):667-9.
2006: James Lin; Hinrich Staecker
Nonorganic hearing loss.
Seminars in neurology 2006;26(3):321-30.
2006: F Van Wijk; Hinrich Staecker; E Keithley; Philippe P Lefebvre
Local perfusion of the tumor necrosis factor alpha blocker infliximab to the inner ear improves autoimmune neurosensory hearing loss.
Audiology & neuro-otology 2006;11(6):357-65.
2006: Hinrich Staecker; Donald Easton; Philip A Mackowiak
The last myrmidon: The life, legacy, and fatal ear disorder of Heinrich Schliemann.
The Pharos of Alpha Omega Alpha-Honor Medical Society. Alpha Omega Alpha 2006;69(2):12-8.
2005: Carrie R Maiorana; Hinrich Staecker
Advances in inner ear gene therapy: exploring cochlear protection and regeneration.
Current opinion in otolaryngology & head and neck surgery 2005;13(5):308-12.
2005: Hinrich Staecker
Broadening the spectrum of treatment options for SNHL.
Archives of otolaryngology--head & neck surgery 2005;131(8):734.
2004: Hinrich Staecker; Douglas E Brough; Mark Praetorius; Kim Baker
Drug delivery to the inner ear using gene therapy.
Otolaryngologic clinics of North America 2004;37(5):1091-108.
2004: Michael Rodrigues; Bert W O'Malley; Hinrich Staecker; Rafael J Tamargo
Extended pericranial flap and bone graft reconstruction in anterior skull base surgery.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2004;131(1):69-76.
2004: Thomas R Van De Water; François Lallemend; Adrien A Eshraghi; Syed Ahsan; Jiao He; Jose Guzman; Marek Polak; Brigitte Malgrange; Philippe P Lefebvre; Hinrich Staecker; Thomas J Balkany
Caspases, the enemy within, and their role in oxidative stress-induced apoptosis of inner ear sensory cells.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 2004;25(4):627-32.
2003: Julie Berry; Bert W O'Malley; Steve Humphries; Hinrich Staecker
Making image guidance work: understanding control of accuracy.
The Annals of otology, rhinology, and laryngology 2003;112(8):689-92.
2003: Mark Praetorius; Kim Baker; Corina M Weich; Peter K Plinkert; Hinrich Staecker
Hearing preservation after inner ear gene therapy: the effect of vector and surgical approach.
ORL; journal for oto-rhino-laryngology and its related specialties 2003;65(4):211-4.
2003: Daniel Lee; William H Westra; Hinrich Staecker; Donlin M Long; John K Niparko; William H Slattery
Clinical and histopathologic features of recurrent vestibular schwannoma (acoustic neuroma) after stereotactic radiosurgery.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 2003;24(4):650-60; discussion 660.
2003: Ulysses Scarpidis; Dilip Madnani; Cynthia Shoemaker; Craig H Fletcher; Ken Kojima; Adrien A Eshraghi; Hinrich Staecker; Phillipe Lefebvre; Brigitte Malgrange; Thomas J Balkany; Thomas R Van De Water
Arrest of apoptosis in auditory neurons: implications for sensorineural preservation in cochlear implantation.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 2003;24(3):409-17.
2003: Venkata Kakarlapudi; Robert Sawyer; Hinrich Staecker
The effect of diabetes on sensorineural hearing loss.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 2003;24(3):382-6.
2002: Philippe P Lefebvre; Hinrich Staecker
Steroid perfusion of the inner ear for sudden sensorineural hearing loss after failure of conventional therapy: a pilot study.
Acta oto-laryngologica 2002;122(7):698-702.
2002: Julie A Berry; Susan L Gold; Ellen Alvarez Frederick; William C Gray; Hinrich Staecker
Patient-based outcomes in patients with primary tinnitus undergoing tinnitus retraining therapy.
Archives of otolaryngology--head & neck surgery 2002;128(10):1153-7.
2002: Hinrich Staecker; Philippe P Lefebvre
Autoimmune sensorineural hearing loss improved by tumor necrosis factor-alpha blockade: a case report.
Acta oto-laryngologica 2002;122(6):684-7.
2002: Philippe P Lefebvre; Brigitte Malgrange; François Lallemend; Hinrich Staecker; Gustave Moonen; Thomas R Van De Water
Mechanisms of cell death in the injured auditory system: otoprotective strategies.
Audiology & neuro-otology 2002;7(3):165-70.
2002: Hinrich Staecker
Tinnitus evaluation and treatment: assessment of quality of life indicators.
Acta oto-rhino-laryngologica Belgica 2002;56(4):355-6.
2002: Philippe P Lefebvre; Hinrich Staecker; Thomas R Van De Water; Gustave Moonen; Brigitte Malgrange
Microperfusion of the inner ear.
Acta oto-rhino-laryngologica Belgica 2002;56(4):365-8.
2002: Philippe P Lefebvre; Hinrich Staecker; Thomas R Van De Water; Gustave Moonen; Brigitte Malgrange
Pharmacologic treatment of inner ear: from basic science to the patient.
Acta oto-rhino-laryngologica Belgica 2002;56(1):45-9.
2002: Lori E Fantry; Hinrich Staecker
Vertigo and abacavir.
AIDS patient care and STDs 2002;16(1):5-7.
2001: Hinrich Staecker; Bert W O'Malley; H Eisenberg; B E Yoder
Use of the LandmarXtrade mark Surgical Navigation System in Lateral Skull Base and Temporal Bone Surgery.
Skull base : official journal of North American Skull Base Society ... [et al.] 2001;11(4):245-55.
2001: Hinrich Staecker; Q Y Zheng; Thomas R Van De Water
Oxidative stress in aging in the C57B16/J mouse cochlea.
Acta oto-laryngologica 2001;121(6):666-72.
2001: Hinrich Staecker; D Li; Bert W O'Malley; Thomas R Van De Water
Gene expression in the mammalian cochlea: a study of multiple vector systems.
Acta oto-laryngologica 2001;121(2):157-63.
2000: Hinrich Staecker; Joseph B Nadol; RG Ojeman; S Ronner; Michael J McKenna
Hearing preservation in acoustic neuroma surgery: middle fossa versus retrosigmoid approach.
The American journal of otology 2000;21(3):399-404.
2000: T Huang; A G Cheng; H Stupak; W Liu; A Kim; Hinrich Staecker; Philippe P Lefebvre; Brigitte Malgrange; Richard D Kopke; Gustave Moonen; Thomas R Van De Water
Oxidative stress-induced apoptosis of cochlear sensory cells: otoprotective strategies.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2000;18(2-3):259-70.
2000: Joseph B Nadol; Hinrich Staecker; Richard E Gliklich
Outcomes assessment for chronic otitis media: the Chronic Ear Survey.
The Laryngoscope 2000;110(3 Pt 3):32-5.
2000: Hinrich Staecker; Saumil N Merchant
Temporal bone pathology case of the month. Congenital fixation of the incus.
The American journal of otology 2000;21(1):137-8.
1999: Thomas R Van De Water; Hinrich Staecker; M W Halterman; Howard Federoff
Gene therapy in the inner ear. Mechanisms and clinical implications.
Annals of the New York Academy of Sciences 1999;884():345-60.
1999: Hinrich Staecker; H Chow; Joseph B Nadol
Osteomyelitis, lateral sinus thrombosis, and temporal lobe infarction caused by infection of a percutaneous cochlear implant.
The American journal of otology 1999;20(6):726-8.
1999: Brigitte Malgrange; Jean-Michel Rigo; Thomas R Van De Water; Hinrich Staecker; Gustave Moonen; Philippe P Lefebvre
Growth factor therapy to the damaged inner ear: clinical prospects.
International journal of pediatric otorhinolaryngology 1999;49 Suppl 1():S19-25.
1999: P Ashley Wackym; Wesley A King; Dennis S Poe; Glenn A Meyer; Robert G Ojemann; Fred G Barker; P R Walsh; Hinrich Staecker
Adjunctive use of endoscopy during acoustic neuroma surgery.
The Laryngoscope 1999;109(8):1193-201.
1999: Hinrich Staecker; Joseph B Nadol; RG Ojeman; Michael J McKenna
Delayed intracranial abscess after acoustic neuroma surgery: a report of two cases.
The American journal of otology 1999;20(3):369-72.
1998: Brigitte Malgrange; Philippe P Lefebvre; Thomas R Van De Water; C Bonnet; F Monville; Jean-Michel Rigo; Hinrich Staecker; Gustave Moonen
In Vitro Ototoxicity of aminoglycosides and platin derivatives. A semi-automatic assay for sensory hair cell damage in explanted rat organ of corti.
Toxicology in vitro : an international journal published in association with BIBRA 1998;12(6):705-14.
1998: W Liu; Hinrich Staecker; H Stupak; Brigitte Malgrange; P Lefebvre; Thomas R Van De Water
Caspase inhibitors prevent cisplatin-induced apoptosis of auditory sensory cells.
Neuroreport 1998;9(11):2609-14.
1998: Hinrich Staecker; Thomas R Van De Water
Factors controlling hair-cell regeneration/repair in the inner ear.
Current opinion in neurobiology 1998;8(4):480-7.
1998: Hinrich Staecker; R Gabaizadeh; Howard Federoff; Thomas R Van De Water
Brain-derived neurotrophic factor gene therapy prevents spiral ganglion degeneration after hair cell loss.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 1998;119(1):7-13.
1998: JG Feghali; Philippe P Lefebvre; Hinrich Staecker; Richard D Kopke; Dorothy A. Frenz; Brigitte Malgrange; W Liu; Gustave Moonen; Robert J Ruben; Thomas R Van De Water
Mammalian auditory hair cell regeneration/repair and protection: a review and future directions.
Ear, nose, & throat journal 1998;77(4):276, 280, 282-5.
1997: R Gabaizadeh; Hinrich Staecker; W Liu; Thomas R Van De Water
BDNF protection of auditory neurons from cisplatin involves changes in intracellular levels of both reactive oxygen species and glutathione.
Brain research. Molecular brain research 1997;50(1-2):71-8.
1997: Hinrich Staecker; S Dazert; Brigitte Malgrange; Philippe P Lefebvre; A F Ryan; Thomas R Van De Water
Transforming growth factor alpha treatment alters intracellular calcium levels in hair cells and protects them from ototoxic damage in vitro.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 1997;15(4-5):553-62.
1997: R Gabaizadeh; Hinrich Staecker; W Liu; Richard D Kopke; Brigitte Malgrange; Philippe P Lefebvre; Thomas R Van De Water
Protection of both auditory hair cells and auditory neurons from cisplatin induced damage.
Acta oto-laryngologica 1997;117(2):232-8.
1996: Brigitte Malgrange; Philippe P Lefebvre; D Martin; Hinrich Staecker; Thomas R Van De Water; Gustave Moonen
NT-3 has a tropic effect on process outgrowth by postnatal auditory neurones in vitro.
Neuroreport 1996;7(15-17):2495-9.
1996: C J Hartnick; Hinrich Staecker; Brigitte Malgrange; Philippe P Lefebvre; W Liu; Gustave Moonen; Thomas R Van De Water
Neurotrophic effects of BDNF and CNTF, alone and in combination, on postnatal day 5 rat acoustic ganglion neurons.
Journal of neurobiology 1996;30(2):246-54.
1996: Hinrich Staecker; V Galinovic-Schwartz; W Liu; P Lefebvre; Richard D Kopke; Brigitte Malgrange; Gustave Moonen; Thomas R Van De Water
The role of the neurotrophins in maturation and maintenance of postnatal auditory innervation.
The American journal of otology 1996;17(3):486-92.
1996: Hinrich Staecker; Thomas R Van De Water; Philippe P Lefebvre; W Liu; M Moghadassi; V Galinovic-Schwartz; Brigitte Malgrange; Gustave Moonen
NGF, BDNF and NT-3 play unique roles in the in vitro development and patterning of innervation of the mammalian inner ear.
Brain research. Developmental brain research 1996;92(1):49-60.
1996: Brigitte Malgrange; P Lefebvre; Thomas R Van De Water; Hinrich Staecker; Gustave Moonen
Effects of neurotrophins on early auditory neurones in cell culture.
Neuroreport 1996;7(4):913-7.
1996: Hinrich Staecker; Richard D Kopke; Brigitte Malgrange; P Lefebvre; Thomas R Van De Water
NT-3 and/or BDNF therapy prevents loss of auditory neurons following loss of hair cells.
Neuroreport 1996;7(4):889-94.
1996: Richard D Kopke; Hinrich Staecker; P Lefebvre; Brigitte Malgrange; Gustave Moonen; Robert J Ruben; Thomas R Van De Water
Effect of neurotrophic factors on the inner ear: clinical implications.
Acta oto-laryngologica 1996;116(2):248-52.
1996: Thomas R Van De Water; Hinrich Staecker; P Ernfors; Gustave Moonen; Philippe P Lefebvre
Neurotrophic factors as pharmacological agents for the treatment of injured auditory neurons.
Ciba Foundation symposium 1996;196():149-62; discussion 162-6.
1995: Hinrich Staecker; W Liu; C Hartnick; P Lefebvre; Brigitte Malgrange; Gustave Moonen; Thomas R Van De Water
NT-3 combined with CNTF promotes survival of neurons in modiolus-spiral ganglion explants.
Neuroreport 1995;6(11):1533-7.
1994: Philippe P Lefebvre; Brigitte Malgrange; Hinrich Staecker; M Moghadass; Thomas R Van De Water; Gustave Moonen
Neurotrophins affect survival and neuritogenesis by adult injured auditory neurons in vitro.
Neuroreport 1994;5(8):865-8.
1994: E Vazquez; Thomas R Van De Water; M Del Valle; José A Vega; Hinrich Staecker; F Giráldez; J Represa
Pattern of trkB protein-like immunoreactivity in vivo and the in vitro effects of brain-derived neurotrophic factor (BDNF) on developing cochlear and vestibular neurons.
Anatomy and embryology 1994;189(2):157-67.
1994: Hinrich Staecker; M Cammer; R Rubinstein; Thomas R Van De Water
A procedure for RT-PCR amplification of mRNAs on histological specimens.
BioTechniques 1994;16(1):76-80.
1993: Philippe P Lefebvre; Hinrich Staecker; Gustave Moonen; Thomas R Van De Water
Naftidrofuryl affects neurite regeneration by injured adult auditory neurons.
Acta oto-laryngologica 1993;113(4):498-501.
1993: Philippe P Lefebvre; Brigitte Malgrange; Hinrich Staecker; Gustave Moonen; Thomas R Van De Water
Retinoic acid stimulates regeneration of mammalian auditory hair cells.
Science (New York, N.Y.) 1993;260(5108):692-5.
1992: Philippe P Lefebvre; D Martin; Hinrich Staecker; T Weber; Gustave Moonen; Thomas R Van De Water
TGF beta 1 expression is initiated in adult auditory neurons by sectioning of the auditory nerve.
Neuroreport 1992;3(4):295-8.
1992: Philippe P Lefebvre; T Weber; Jean-Michel Rigo; Hinrich Staecker; Gustave Moonen; Thomas R Van De Water
Peripheral and central target-derived trophic factor(s) effects on auditory neurons.
Hearing research 1992;58(2):185-92.
1992: Philippe P Lefebvre; Thomas R Van De Water; Hinrich Staecker; T Weber; V Galinović-Schwartz; Gustave Moonen; Robert J Ruben
Nerve growth factor stimulates neurite regeneration but not survival of adult auditory neurons in vitro.
Acta oto-laryngologica 1992;112(2):288-93.
1991: Philippe P Lefebvre; Hinrich Staecker; T Weber; Thomas R Van De Water; Bernard Rogister; Gustave Moonen
TGFSS1 modulates bFGF receptor message expression in cultured adult auditory neurons.
Neuroreport 1991;2(6):305-8.
1991: Dorothy A. Frenz; V Galinovic-Schwartz; Hinrich Staecker; Thomas R Van De Water
Transforming growth factor-beta. Paracrine mediator of otic capsule formation.
Annals of the New York Academy of Sciences 1991;630():253-5.