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Dan Staerk

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Iran

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Publications

TOP 3
Clara Grosso; Anna K Jäger; Dan Staerk
Coupling of a high-resolution monoamine oxidase-A inhibitor assay and HPLC-SPE-NMR for advanced bioactivity profiling of plant extracts.
Jeppe S Schmidt; Lars O Dragsted; Michael B Lauridsen; John Nielsen; Dan Staerk
Development of a bioassay-coupled HPLC-SPE-ttNMR platform for identification of α-glucosidase inhibitors in apple peel (Malus ×domestica Borkh.).
Sara Agnolet; Robert Verpoorte; Stefanie Wiese; Dan Staerk
Comprehensive analysis of commercial willow bark extracts by new technology platform: combined use of metabolomics, high-performance liquid chromatography-solid-phase extraction-nuclear magnetic resonance spectroscopy and high-resolution radical scavenging assay.

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All Publications

2013: Clara Grosso; Anna K Jäger; Dan Staerk
Coupling of a high-resolution monoamine oxidase-A inhibitor assay and HPLC-SPE-NMR for advanced bioactivity profiling of plant extracts.
Phytochemical analysis : PCA 2013;24(2):141-7.
2012: Jeppe S Schmidt; Lars O Dragsted; Michael B Lauridsen; John Nielsen; Dan Staerk
Development of a bioassay-coupled HPLC-SPE-ttNMR platform for identification of α-glucosidase inhibitors in apple peel (Malus ×domestica Borkh.).
Food chemistry 2012;135(3):1692-9.
2012: Sara Agnolet; Robert Verpoorte; Stefanie Wiese; Dan Staerk
Comprehensive analysis of commercial willow bark extracts by new technology platform: combined use of metabolomics, high-performance liquid chromatography-solid-phase extraction-nuclear magnetic resonance spectroscopy and high-resolution radical scavenging assay.
Journal of chromatography. A 2012;1262():130-7.
2012: Anders N Hansen; Christine D Bendiksen; Tina Friis; Flemming Steen Jørgensen; Christian A Olsen; Dan Staerk; Lene Sylvest; Gunnar Houen
Synthesis and antiangiogenic activity of N-alkylated levamisole derivatives.
PloS one 2012;7(9):e45405.
2011: Julie R Kesting; Kukkundoor R Kini; Lars Olsen; Harishchandra S Prakash; Dan Staerk; Tejesvi Mysore; Jerzy W Jaroszewski
Production of unusual dispiro metabolites in Pestalotiopsis virgatula endophyte cultures: HPLC-SPE-NMR, electronic circular dichroism, and time-dependent density-functional computation study.
Journal of natural products 2011;74(10):2206-15.
2009: Julie R Kesting; Dan Staerk; Mysore V Tejesvi; Kukkundoor R Kini; Harishchandra S Prakash; Jerzy W Jaroszewski
HPLC-SPE-NMR identification of a novel metabolite containing the benzo[c]oxepin skeleton from the endophytic fungus Pestalotiopsis virgatula culture.
Planta medica 2009;75(10):1104-6.
2009: Dan Staerk; Julie R Kesting; Majid Sairafianpour; Matthias Witt; Javad Asili; Seyed A Emami; Jerzy W Jaroszewski
Accelerated dereplication of crude extracts using HPLC-PDA-MS-SPE-NMR: quinolinone alkaloids of Haplophyllum acutifolium.
Phytochemistry 2009;70(8):1055-61.
2009: Jesper Larsen; Dan Staerk; Claus Cornett; Steen H Hansen; Jerzy W Jaroszewski
Identification of reaction products between drug substances and excipients by HPLC-SPE-NMR: ester and amide formation between citric acid and 5-aminosalicylic acid.
Journal of pharmaceutical and biomedical analysis 2009;49(3):839-42.
2009: Martin M Pedersen; Jude C Chukwujekwu; Carmen A Lategan; Johannes van Staden; Peter J Smith; Dan Staerk
Antimalarial sesquiterpene lactones from Distephanus angulifolius.
Phytochemistry 2009;70(5):601-7.
2009: Julie R Kesting; Inge-Lise Tolderlund; Anders F Pedersen; Matthias Witt; Jerzy W Jaroszewski; Dan Staerk
Piperidine and tetrahydropyridine alkaloids from Lobelia siphilitica and Hippobroma longiflora.
Journal of natural products 2009;72(2):312-5.
2009: Anders Juul Lawaetz; Bonnie Schmidt; Dan Staerk; Jerzy W Jaroszewski; Rasmus Bro
Application of rotated PCA models to facilitate interpretation of metabolite profiles: commercial preparations of St. John's Wort.
Planta medica 2009;75(3):271-9.
2008: François Crestey; Matthias Witt; Karla Frydenvang; Dan Staerk; Jerzy W Jaroszewski; Henrik Franzyk
Microwave-assisted ring-opening of activated aziridines with resin-bound amines.
The Journal of organic chemistry 2008;73(9):3566-9.
2008: Bonnie Schmidt; Jerzy W Jaroszewski; Rasmus Bro; Matthias Witt; Dan Staerk
Combining PARAFAC analysis of HPLC-PDA profiles and structural characterization using HPLC-PDA-SPE-NMR-MS experiments: commercial preparations of St. John's Wort.
Analytical chemistry 2008;80(6):1978-87.
2007: Kennett Sprogøe; Dan Staerk; Anna K Jäger; Anne Adsersen; Steen H Hansen; Matthias Witt; Anne-Katrine R Landbo; Anne S Meyer; Jerzy W Jaroszewski
Targeted natural product isolation guided by HPLC-SPE-NMR: constituents of Hubertia species.
Journal of natural products 2007;70(9):1472-7.
2007: Maja Lambery; Jean-Luc Wolfender; Dan Staerk; S Brøgger Christensen; Kurt Hostettmann; Jerzy W Jaroszewski
Identification of natural products using HPLC-SPE combined with CapNMR.
Analytical chemistry 2007;79(2):727-35.
2006: Dan Staerk; Bishnu P Chapagain; Therese Lindin; Zeev Wiesman; Jerzy W Jaroszewski
Structural analysis of complex saponins of Balanites aegyptiaca by 800 MHz 1H NMR spectroscopy.
Magnetic resonance in chemistry : MRC 2006;44(10):923-8.
2006: Bonnie Rasmussen; Aimee-Justine Nkurunziza; Matthias Witt; Hellen Oketch-Rabah; Jerzy W Jaroszewski; Dan Staerk
Dovyalicin-type spermidine alkaloids from Dovyalis species.
Journal of natural products 2006;69(9):1300-4.
2006: Cailean Clarkson; Dan Staerk; Steen H Hansen; Peter J Smith; Jerzy W Jaroszewski
Identification of major and minor constituents of Harpagophytum procumbens (Devil's claw) using HPLC-SPE-NMR and HPLC-ESIMS/APCIMS.
Journal of natural products 2006;69(9):1280-8.
2006: Bonnie Rasmussen; Olivier Cloarec; Huiru Tang; Dan Staerk; Jerzy W Jaroszewski
Multivariate analysis of integrated and full-resolution 1H-NMR spectral data from complex pharmaceutical preparations: St. John's wort.
Planta medica 2006;72(6):556-63.
2006: Cailean Clarkson; Dan Staerk; Steen H Hansen; Peter J Smith; Jerzy W Jaroszewski
Discovering new natural products directly from crude extracts by HPLC-SPE-NMR: chinane diterpenes in Harpagophytum procumbens.
Journal of natural products 2006;69(4):527-30.
2005: Maja Lambery; Dan Staerk; Steen H Hansen; Majid Sairafianpour; Jerzy W Jaroszewski
Rapid extract dereplication using HPLC-SPE-NMR: analysis of isoflavonoids from Smirnowia iranica.
Journal of natural products 2005;68(10):1500-9.
2005: Maja Lambert; Dan Staerk; Steen H Hansen; Jerzy W Jaroszewski
HPLC-SPE-NMR hyphenation in natural products research: optimization of analysis of Croton membranaceus extract.
Magnetic resonance in chemistry : MRC 2005;43(9):771-5.
2005: Cailean Clarkson; Dan Staerk; Steen H Hansen; Jerzy W Jaroszewski
Hyphenation of solid-phase extraction with liquid chromatography and nuclear magnetic resonance: application of HPLC-DAD-SPE-NMR to identification of constituents of Kanahia laniflora.
Analytical chemistry 2005;77(11):3547-53.
2005: Jerzy W Jaroszewski; Dan Staerk; Sören Boe Holm-Móller; Thomas Hógh Jensen; Henrik Franzyk; Brinda Somanadhan
Naravelia zeylanica [corrected] occurrence of primary benzamides in flowering plants.
Natural product research 2005;19(3):291-4.
2004: Karsten Petersson; Brian Thoning Pedersen; Dan Staerk; Karen A Krogfelt; Claus Larsen
N4-alkyloxycarbonyl derivatives of cytosine: physicochemical characterisation, and cytosine regeneration rates and release from alginic acid gels.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2004;23(4-5):337-45.
2004: Hanne L Ziegler; Harald Hansen; Dan Staerk; S Brøgger Christensen; Henry Hägerstrand; Jerzy W Jaroszewski
The antiparasitic compound licochalcone a is a potent echinocytogenic agent that modifies the erythrocyte membrane in the concentration range where antiplasmodial activity is observed.
Antimicrobial agents and chemotherapy 2004;48(10):4067-71.
2004: Dan Staerk; Jesper Larsen; Line A Larsen; Elin Olafsdottir; Matthias Witt; Jerzy W Jaroszewski
Selagoline, a new alkaloid from Huperzia selago.
Natural product research 2004;18(3):197-203.
2004: Dan Staerk; Brian Skole; Flemming Steen Jørgensen; Bogdan A Budnik; Patrick Ekpe; Jerzy W Jaroszewski
Isolation of a library of aromadendranes from Landolphia dulcis and its characterization using the VolSurf approach.
Journal of natural products 2004;67(5):799-805.
2004: Gerhard Bringmann; Michael Dreyer; Johan Faber; Petur W Dalsgaard; Dan Staerk; Jerzy W Jaroszewski; Henry Ndangalasi; Frank Mbago; Reto Brun; S Brøgger Christensen
Ancistrotanzanine C and related 5,1'- and 7,3'-coupled naphthylisoquinoline alkaloids from Ancistrocladus tanzaniensis.
Journal of natural products 2004;67(5):743-8.
2004: Javad Asili; Maja Lambery; Hanne L Ziegler; Dan Staerk; Majid Sairafianpour; Matthias Witt; Gholamreza Asghari; Ismaiel S Ibrahimi; Jerzy W Jaroszewski
Labdanes and isopimaranes from Platycladus orientalis and their effects on erythrocyte membrane and on Plasmodium falciparum growth in the erythrocyte host cells.
Journal of natural products 2004;67(4):631-7.
2004: Hanne L Ziegler; Henrik Franzyk; Majid Sairafianpour; Mehrnoush Tabatabai; Mahboubeh D Tehrani; Karim Bagherzadeh; Henry Hägerstrand; Dan Staerk; Jerzy W Jaroszewski
Erythrocyte membrane modifying agents and the inhibition of Plasmodium falciparum growth: structure-activity relationships for betulinic acid analogues.
Bioorganic & medicinal chemistry 2004;12(1):119-27.
2003: Majid Sairafianpour; Babak Bahreininejad; Matthias Witt; Hanne L Ziegler; Jerzy W Jaroszewski; Dan Staerk
Terpenoids of Salvia hydrangea: two new, rearranged 20-norabietanes and the effect of oleanolic acid on erythrocyte membranes.
Planta medica 2003;69(9):846-50.
2003: Gerhard Bringmann; Michael Dreyer; Johan Faber; Petur W Dalsgaard; Dan Staerk; Jerzy W Jaroszewski; Henry Ndangalasi; Frank Mbago; Reto Brun; Matthias Reichert; Katja Maksimenka; S Brøgger Christensen
Ancistrotanzanine A, the first 5,3'-coupled naphthylisoquinoline alkaloid, and two further, 5,8'-linked related compounds from the newly described species Ancistrocladus tanzaniensis.
Journal of natural products 2003;66(9):1159-65.
2003: Dan Staerk; Matthias Witt; Hellen Oketch-Rabah; Jerzy W Jaroszewski
A new class of spermidine-derived alkaloids.
Organic letters 2003;5(16):2793-6.
2002: Hanne L Ziegler; Dan Staerk; Jette Christensen; Carl Erik Olsen; Archibald A Sittie; Jerzy W Jaroszewski
New dammarane and malabaricane triterpenes from Caloncoba echinata.
Journal of natural products 2002;65(12):1764-8.
2002: Majid Sairafianpour; Oliver Kayser; Jette Christensen; Mohammad Asfa; Matthias Witt; Dan Staerk; Jerzy W Jaroszewski
Leishmanicidal and antiplasmodial activity of constituents of Smirnowia iranica.
Journal of natural products 2002;65(12):1754-8.
2002: Dan Staerk; Anne K Lykkeberg; Jette Christensen; Bogdan A Budnik; Fumiko Abe; Jerzy W Jaroszewski
In vitro cytotoxic activity of phenanthroindolizidine alkaloids from Cynanchum vincetoxicum and Tylophora tanakae against drug-sensitive and multidrug-resistant cancer cells.
Journal of natural products 2002;65(9):1299-302.
2002: Hanne L Ziegler; Thomas Høgh Jensen; Jette Christensen; Dan Staerk; Henry Hägerstrand; Archibald A Sittie; Carl Erik Olsen; Trine Staalsø; Patrick Ekpe; Jerzy W Jaroszewski
Possible artefacts in the in vitro determination of antimalarial activity of natural products that incorporate into lipid bilayer: apparent antiplasmodial activity of dehydroabietinol, a constituent of Hyptis suaveolens.
Planta medica 2002;68(6):547-9.
2002: Hanne L Ziegler; Dan Staerk; Jette Christensen; Lars Hviid; Henry Hägerstrand; Jerzy W Jaroszewski
In vitro Plasmodium falciparum drug sensitivity assay: inhibition of parasite growth by incorporation of stomatocytogenic amphiphiles into the erythrocyte membrane.
Antimicrobial agents and chemotherapy 2002;46(5):1441-6.
2001: Majid Sairafianpour; Jette Christensen; Dan Staerk; Bogdan A Budnik; Arsalan Kharazmi; K Bagherzadeh; Jerzy W Jaroszewski
Leishmanicidal, antiplasmodial, and cytotoxic activity of novel diterpenoid 1,2-quinones from Perovskia abrotanoides: new source of tanshinones.
Journal of natural products 2001;64(11):1398-403.
2001: Dan Staerk; Per-Ola Norrby; Jerzy W Jaroszewski
Conformational analysis of indole alkaloids corynantheine and dihydrocorynantheine by dynamic 1H NMR spectroscopy and computational methods: steric effects of ethyl vs vinyl group.
The Journal of organic chemistry 2001;66(7):2217-21.
2000: Dan Staerk; Jette Christensen; E Lemmich; Jens O Duus; Carl Erik Olsen; Jerzy W Jaroszewski
Cytotoxic activity of some phenanthroindolizidine N-oxide alkaloids from Cynanchum vincetoxicum.
Journal of natural products 2000;63(11):1584-6.
2000: Dan Staerk; E Lemmich; Jette Christensen; Arsalan Kharazmi; Carl Erik Olsen; Jerzy W Jaroszewski
Leishmanicidal, antiplasmodial and cytotoxic activity of indole alkaloids from Corynanthe pachyceras.
Planta medica 2000;66(6):531-6.