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Thomas Stamminger

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Cytomegalovirus

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Nadine Frankenberg; Peter Lischka; Sandra Pepperl-Klindworth; Thomas Stamminger; Bodo Plachter
Nucleocytoplasmic shuttling and CRM1-dependent MHC class I peptide presentation of human cytomegalovirus pp65.
Stefan Sörgel; Thomas Stamminger; Marco Thomas; Jörg Votteler; Kirsten Fraedrich; Ulrich Schubert
Perinuclear localization of the HIV-1 regulatory protein Vpr is important for induction of G2-arrest.
Barbara Zielke; Katrin Zielke; Caroline Pfeifer; Marco Thomas; Nadine Wagenknecht; Thomas Stamminger
Transfer of the UAP56 interaction motif of human cytomegalovirus pUL69 to its murine cytomegalovirus homolog converts the protein into a functional mRNA export factor that can substitute for pUL69 during viral infection.

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2012: Nadine Frankenberg; Peter Lischka; Sandra Pepperl-Klindworth; Thomas Stamminger; Bodo Plachter
Nucleocytoplasmic shuttling and CRM1-dependent MHC class I peptide presentation of human cytomegalovirus pp65.
Medical microbiology and immunology 2012;201(4):567-79.
2012: Stefan Sörgel; Thomas Stamminger; Marco Thomas; Jörg Votteler; Kirsten Fraedrich; Ulrich Schubert
Perinuclear localization of the HIV-1 regulatory protein Vpr is important for induction of G2-arrest.
Virology 2012;432(2):444-51.
2012: Barbara Zielke; Katrin Zielke; Caroline Pfeifer; Marco Thomas; Nadine Wagenknecht; Thomas Stamminger
Transfer of the UAP56 interaction motif of human cytomegalovirus pUL69 to its murine cytomegalovirus homolog converts the protein into a functional mRNA export factor that can substitute for pUL69 during viral infection.
Journal of virology 2012;86(13):7448-53.
2012: S Abele-Ohl; C Heim; J Hoffmann; Martina Leis; S Mahmoudian; R Müller; Bernd M Spriewald; Thomas Stamminger; Michael Weyand; M Wollin; Stephan Ensminger
Human cytomegalovirus infection leads to elevated levels of transplant arteriosclerosis in a humanized mouse aortic xenograft model.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2012;12(7):1720-9.
2012: Manfred Marschall; Helga Ruebsamen-Schaeff; Thomas Stamminger; Andreas Urban; Steffen Wildum; Holger Zimmermann; Peter Lischka
In vitro evaluation of the activities of the novel anticytomegalovirus compound AIC246 (letermovir) against herpesviruses and other human pathogenic viruses.
Antimicrobial agents and chemotherapy 2012;56(2):1135-7.
2011: Martin Zydek; Christian Hagemeier; Thomas Stamminger; Nina Tavalai; Ralf Uecker; Lüder Wiebusch
General blockade of human cytomegalovirus immediate-early mRNA expression in the S/G2 phase by a nuclear, Daxx- and PML-independent mechanism.
The Journal of general virology 2011;92(Pt 12):2757-69.
2011: Sunwen Chou; Gail Marousek; Jens Milbradt; Thomas Stamminger; Sabrina Auerochs; Manfred Marschall
The unique antiviral activity of artesunate is broadly effective against human cytomegaloviruses including therapy-resistant mutants.
Antiviral research 2011;92(2):364-8.
2011: Ana Kralj; Shohreh Mahmoudian; Thomas Stamminger; Nuska Tschammer; Alexander Wetzel; Markus R Heinrich
Identification of novel allosteric modulators for the G-protein coupled US28 receptor of human cytomegalovirus.
Bioorganic & medicinal chemistry letters 2011;21(18):5446-50.
2011: Nina Tavalai; Martina Adler; Yvonne Riedl; Myriam Scherer; Thomas Stamminger
Evidence for a dual antiviral role of the major nuclear domain 10 component Sp100 during the immediate-early and late phases of the human cytomegalovirus replication cycle.
Journal of virology 2011;85(18):9447-58.
2011: Sonja Pötzsch; Pia Rücker; Nadja Spindler; Thomas Stamminger; Heinrich Sticht; Florian Weisel; Anna-Katharina Wiegers; Tina Baroti; Tanja Fisch; Nina Grieb; Michael Mach; Luis Martin-Parras; Thomas H Winkler
B cell repertoire analysis identifies new antigenic domains on glycoprotein B of human cytomegalovirus which are target of neutralizing antibodies.
PLoS pathogens 2011;7(8):e1002172.
2011: Martina Adler; Regina Müller; Nina Tavalai; Thomas Stamminger
Human cytomegalovirus immediate-early gene expression is restricted by the nuclear domain 10 component Sp100.
The Journal of general virology 2011;92(Pt 7):1532-8.
2011: Sabine Feichtinger; Laura Graf; Bert Klebl; Regina Müller; Thomas Stamminger; Jan Eickhoff; Manfred Marschall
Recruitment of cyclin-dependent kinase 9 to nuclear compartments during cytomegalovirus late replication: importance of an interaction between viral pUL69 and cyclin T1.
The Journal of general virology 2011;92(Pt 7):1519-31.
2011: H Zakaryan; Thomas Stamminger
Nuclear remodelling during viral infections.
Cellular microbiology 2011;13(6):806-13.
2011: Dana G Wolf; Avichai Shimoni; Igor B Resnick; Thomas Stamminger; Avidan U Neumann; Sunwen Chou; Thomas Efferth; Orit Caplan; Jessica Rose; Arnon Nagler; Manfred Marschall
Human cytomegalovirus kinetics following institution of artesunate after hematopoietic stem cell transplantation.
Antiviral research 2011;90(3):183-6.
2011: Nina Tavalai; Thomas Stamminger
Intrinsic cellular defense mechanisms targeting human cytomegalovirus.
Virus research 2011;157(2):128-33.
2011: Barbara Zielke; Marco Thomas; Antje Giede-Jeppe; Regina Müller; Thomas Stamminger
Characterization of the betaherpesviral pUL69 protein family reveals binding of the cellular mRNA export factor UAP56 as a prerequisite for stimulation of nuclear mRNA export and for efficient viral replication.
Journal of virology 2011;85(4):1804-19.
2011: Marco Thomas; Peter Lischka; Regina Müller; Thomas Stamminger
The cellular DExD/H-box RNA-helicases UAP56 and URH49 exhibit a CRM1-independent nucleocytoplasmic shuttling activity.
PloS one 2011;6(7):e22671.
2011: Mengxi Jiang; Pouya Entezami; Monica Gamez; Thomas Stamminger; Michael J Imperiale
Functional reorganization of promyelocytic leukemia nuclear bodies during BK virus infection.
mBio 2011;2(1):e00281-10.
2010: Christian Heim; Silke Abele-Ohl; Sebastian Eckl; Martina Ramsperger-Gleixner; Shohreh Mahmoudian; Michael Weyand; Thomas Stamminger; Stephan Ensminger
Murine cytomegalovirus infection leads to increased levels of transplant arteriosclerosis in a murine aortic allograft model.
Transplantation 2010;90(4):373-9.
2010: Silke Abele-Ohl; Martina Leis; Shohreh Mahmoudian; Michael Weyand; Thomas Stamminger; Stephan Ensminger
Rag2-/- gamma-chain-/- mice as hosts for human vessel transplantation and allogeneic human leukocyte reconstitution.
Transplant immunology 2010;23(1-2):59-64.
2009: Nina Tavalai; Thomas Stamminger
Interplay between Herpesvirus Infection and Host Defense by PML Nuclear Bodies.
Viruses 2009;1(3):1240-64.
2009: Anja Berndt; Heike Hofmann-Winkler; Nina Tavalai; Gabriele Hahn; Thomas Stamminger
Importance of covalent and noncovalent SUMO interactions with the major human cytomegalovirus transactivator IE2p86 for viral infection.
Journal of virology 2009;83(24):12881-94.
2009: Nina Kaiser; Peter Lischka; Nadine Wagenknecht; Thomas Stamminger
Inhibition of human cytomegalovirus replication via peptide aptamers directed against the nonconventional nuclear localization signal of the essential viral replication factor pUL84.
Journal of virology 2009;83(22):11902-13.
2009: Manfred Marschall; Thomas Stamminger
Molecular targets for antiviral therapy of cytomegalovirus infections.
Future microbiology 2009;4(6):731-42.
2009: Sabine Rechter; Gillian M Scott; Jan Eickhoff; Katrin Zielke; Sabrina Auerochs; Regina Müller; Thomas Stamminger; William D Rawlinson; Manfred Marschall
Cyclin-dependent Kinases Phosphorylate the Cytomegalovirus RNA Export Protein pUL69 and Modulate Its Nuclear Localization and Activity.
The Journal of biological chemistry 2009;284(13):8605-13.
2009: Marco Thomas; Sabine Rechter; Jens Milbradt; Sabrina Auerochs; Regina Müller; Thomas Stamminger; Manfred Marschall
Cytomegaloviral protein kinase pUL97 interacts with the nuclear mRNA export factor pUL69 to modulate its intranuclear localization and activity.
The Journal of general virology 2009;90(Pt 3):567-78.
2008: Nina Tavalai; Thomas Stamminger
New insights into the role of the subnuclear structure ND10 for viral infection.
Biochimica et biophysica acta 2008;1783(11):2207-21.
2008: Nina Tavalai; Martina Kraiger; Nina Kaiser; Thomas Stamminger
Insertion of an EYFP-pp71 (UL82) coding sequence into the human cytomegalovirus genome results in a recombinant virus with enhanced viral growth.
Journal of virology 2008;82(21):10543-55.
2008: Thomas Efferth; Marta R Romero; Dana G Wolf; Thomas Stamminger; Jose J G Marin; Manfred Marschall
The antiviral activities of artemisinin and artesunate.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2008;47(6):804-11.
2008: Mark R Schleiss; Jan Eickhoff; Sabrina Auerochs; Martina Leis; Silke Abele; Sabine Rechter; Yeon Choi; Jodi Anderson; Gillian Scott; William Rawlinson; Detlef Michel; Stephan Ensminger; Bert Klebl; Thomas Stamminger; Manfred Marschall
Protein kinase inhibitors of the quinazoline class exert anti-cytomegaloviral activity in vitro and in vivo.
Antiviral research 2008;79(1):49-61.
2008: Michael Y Shapira; Igor B Resnick; Sunwen Chou; Avidan U Neumann; Nell S Lurain; Thomas Stamminger; Orit Caplan; Niveen Saleh; Thomas Efferth; Manfred Marschall; Dana G Wolf
Artesunate as a potent antiviral agent in a patient with late drug-resistant cytomegalovirus infection after hematopoietic stem cell transplantation.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2008;46(9):1455-7.
2008: Marion Kaspari; Nina Tavalai; Thomas Stamminger; Albert Zimmermann; Rita Schilf; Elke Bogner
Proteasome inhibitor MG132 blocks viral DNA replication and assembly of human cytomegalovirus.
FEBS letters 2008;582(5):666-72.
2008: Thomas Stamminger
Interactions of human cytomegalovirus proteins with the nuclear transport machinery.
Current topics in microbiology and immunology 2008;325():167-85.
2008: Zsolt Toth; Thomas Stamminger
The human cytomegalovirus regulatory protein UL69 and its effect on mRNA export.
Frontiers in bioscience : a journal and virtual library 2008;13():2939-49.
2008: Nina Tavalai; Peer Papior; Sabine Rechter; Thomas Stamminger
Nuclear domain 10 components promyelocytic leukemia protein and hDaxx independently contribute to an intrinsic antiviral defense against human cytomegalovirus infection.
Journal of virology 2008;82(1):126-37.
2007: George Sourvinos; Nina Tavalai; Anja Berndt; Demetrios A Spandidos; Thomas Stamminger
Recruitment of human cytomegalovirus immediate-early 2 protein onto parental viral genomes in association with ND10 in live-infected cells.
Journal of virology 2007;81(18):10123-36.
2007: Peter Lischka; Marco Thomas; Zsolt Toth; Regina Mueller; Thomas Stamminger
Multimerization of human cytomegalovirus regulatory protein UL69 via a domain that is conserved within its herpesvirus homologues.
The Journal of general virology 2007;88(Pt 2):405-10.
2007: Vera Schregel; Sabrina Auerochs; Ramona Jochmann; Katja Maurer; Thomas Stamminger; Manfred Marschall
Mapping of a self-interaction domain of the cytomegalovirus protein kinase pUL97.
The Journal of general virology 2007;88(Pt 2):395-404.
2006: Peter Lischka; Claudia Rauh; Regina Mueller; Thomas Stamminger
Human cytomegalovirus UL84 protein contains two nuclear export signals and shuttles between the nucleus and the cytoplasm.
Journal of virology 2006;80(20):10274-80.
2006: Sabine Raab; Zsolt Toth; Christian de Groot; Thomas Stamminger; Stefan Hoth
ABA-responsive RNA-binding proteins are involved in chloroplast and stromule function in Arabidopsis seedlings.
Planta 2006;224(4):900-14.
2006: Nina Tavalai; Peer Papior; Sabine Rechter; Martina Leis; Thomas Stamminger
Evidence for a role of the cellular ND10 protein PML in mediating intrinsic immunity against human cytomegalovirus infections.
Journal of virology 2006;80(16):8006-18.
2006: Roger D Everett; Sabine Rechter; Peer Papior; Nina Tavalai; Thomas Stamminger; Anne Orr
PML contributes to a cellular mechanism of repression of herpes simplex virus type 1 infection that is inactivated by ICP0.
Journal of virology 2006;80(16):7995-8005.
2006: Kerstin Lorz; Heike Hofmann; Anja Berndt; Nina Tavalai; Regina Mueller; Ursula Schlötzer-Schrehardt; Thomas Stamminger
Deletion of open reading frame UL26 from the human cytomegalovirus genome results in reduced viral growth, which involves impaired stability of viral particles.
Journal of virology 2006;80(11):5423-34.
2006: Peter Lischka; Zsolt Toth; Marco Thomas; Regina Mueller; Thomas Stamminger
The UL69 transactivator protein of human cytomegalovirus interacts with DEXD/H-Box RNA helicase UAP56 to promote cytoplasmic accumulation of unspliced RNA.
Molecular and cellular biology 2006;26(5):1631-43.
2006: Suzanne J F Kaptein; Thomas Efferth; Martina Leis; Sabine Rechter; Sabrina Auerochs; Martina Kalmer; Cathrien A Bruggeman; Cornelis Vink; Thomas Stamminger; Manfred Marschall
The anti-malaria drug artesunate inhibits replication of cytomegalovirus in vitro and in vivo.
Antiviral research 2006;69(2):60-9.
2006: Zsolt Toth; Peter Lischka; Thomas Stamminger
RNA-binding of the human cytomegalovirus transactivator protein UL69, mediated by arginine-rich motifs, is not required for nuclear export of unspliced RNA.
Nucleic acids research 2006;34(4):1237-49.
2005: Manfred Marschall; Andrea Marzi; Patricia aus dem Siepen; Ramona Jochmann; Martina Kalmer; Sabrina Auerochs; Peter Lischka; Martina Leis; Thomas Stamminger
Cellular p32 recruits cytomegalovirus kinase pUL97 to redistribute the nuclear lamina.
The Journal of biological chemistry 2005;280(39):33357-67.
2005: Helmut Mett; Kerstin Hölscher; Heidrun Degen; Christina Esdar; Birgit Felden De Neumann; Birgit Flicke; Tatjana Freudenreich; Gaby Holzer; Sieglinde Schinzel; Thomas Stamminger; Matthias Stein-Gerlach; Manfred Marschall; Thomas Herget
Identification of inhibitors for a virally encoded protein kinase by 2 different screening systems: in vitro kinase assay and in-cell activity assay.
Journal of biomolecular screening 2005;10(1):36-45.
2004: Thomas Herget; Martina Freitag; Monika Morbitzer; Regina Kupfer; Thomas Stamminger; Manfred Marschall
Novel chemical class of pUL97 protein kinase-specific inhibitors with strong anticytomegaloviral activity.
Antimicrobial agents and chemotherapy 2004;48(11):4154-62.
2004: Thomas Efferth; Achille Benakis; Marta R Romero; Maja T Tomicic; Rolf Rauh; Daniel Steinbach; Ralf Häfer; Thomas Stamminger; Franz Oesch; Bernd Kaina; Manfred Marschall
Enhancement of cytotoxicity of artemisinins toward cancer cells by ferrous iron.
Free radical biology & medicine 2004;37(7):998-1009.
2004: Karina Schierling; Thomas Stamminger; Thomas Mertens; Michael Winkler
Human cytomegalovirus tegument proteins ppUL82 (pp71) and ppUL35 interact and cooperatively activate the major immediate-early enhancer.
Journal of virology 2004;78(17):9512-23.
2004: Martina Leis; Manfred Marschall; Thomas Stamminger
Downregulation of the cellular adhesion molecule Thy-1 (CD90) by cytomegalovirus infection of human fibroblasts.
The Journal of general virology 2004;85(Pt 7):1995-2000.
2004: Jan Eickhoff; Miriam Hanke; Matthias Stein-Gerlach; Tan Poi Kiang; Katrin Herzberger; Peter Habenberger; Stefan Müller; Bert Klebl; Manfred Marschall; Thomas Stamminger; Matt Cotten
RICK activates a NF-kappaB-dependent anti-human cytomegalovirus response.
The Journal of biological chemistry 2004;279(10):9642-52.
2003: Said Hashemolhosseini; Karin Kilian; Elena Kardash; Peter Lischka; Thomas Stamminger; Michael Wegner
Structural requirements for nuclear localization of GCMa/Gcm-1.
FEBS letters 2003;553(3):315-20.
2003: Manfred Marschall; Martina Freitag; Patricia Suchy; Daniel Romaker; Regina Kupfer; Miriam Hanke; Thomas Stamminger
The protein kinase pUL97 of human cytomegalovirus interacts with and phosphorylates the DNA polymerase processivity factor pUL44.
Virology 2003;311(1):60-71.
2003: Peter Lischka; Gabriele Sorg; Michael Kann; Michael Winkler; Thomas Stamminger
A nonconventional nuclear localization signal within the UL84 protein of human cytomegalovirus mediates nuclear import via the importin alpha/beta pathway.
Journal of virology 2003;77(6):3734-48.
2003: Martina Kronschnabl; Thomas Stamminger
Synergistic induction of intercellular adhesion molecule-1 by the human cytomegalovirus transactivators IE2p86 and pp71 is mediated via an Sp1-binding site.
The Journal of general virology 2003;84(Pt 1):61-73.
2002: Stephan Rehberg; Peter Lischka; Gabi Glaser; Thomas Stamminger; Michael Wegner; Olaf Rosorius
Sox10 is an active nucleocytoplasmic shuttle protein, and shuttling is crucial for Sox10-mediated transactivation.
Molecular and cellular biology 2002;22(16):5826-34.
2002: Heike Hofmann; Hilde Sindre; Thomas Stamminger
Functional interaction between the pp71 protein of human cytomegalovirus and the PML-interacting protein human Daxx.
Journal of virology 2002;76(11):5769-83.
2002: Thomas Stamminger; Matthias Gstaiger; Konstanze Weinzierl; Kerstin Lorz; Michael Winkler; Walter Schaffner
Open reading frame UL26 of human cytomegalovirus encodes a novel tegument protein that contains a strong transcriptional activation domain.
Journal of virology 2002;76(10):4836-47.
2002: Manfred Marschall; Matthias Stein-Gerlach; Martina Freitag; Regina Kupfer; Miriam van den Bogaard; Thomas Stamminger
Direct targeting of human cytomegalovirus protein kinase pUL97 by kinase inhibitors is a novel principle for antiviral therapy.
The Journal of general virology 2002;83(Pt 5):1013-23.
2002: Thomas Efferth; Manfred Marschall; Xin Wang; Shu-Mei Huong; Ilona Hauber; Armin Olbrich; Martina Kronschnabl; Thomas Stamminger; Eng-Shang Huang
Antiviral activity of artesunate towards wild-type, recombinant, and ganciclovir-resistant human cytomegaloviruses.
Journal of molecular medicine (Berlin, Germany) 2002;80(4):233-42.
2002: Martina Kronschnabl; Manfred Marschall; Thomas Stamminger
Efficient and tightly regulated expression systems for the human cytomegalovirus major transactivator protein IE2p86 in permissive cells.
Virus research 2002;83(1-2):89-102.
2001: Peter Lischka; Olaf Rosorius; E Trommer; Thomas Stamminger
A novel transferable nuclear export signal mediates CRM1-independent nucleocytoplasmic shuttling of the human cytomegalovirus transactivator protein pUL69.
The EMBO journal 2001;20(24):7271-83.
2001: Manfred Marschall; Matthias Stein-Gerlach; Martina Freitag; Regina Kupfer; M van Den Bogaard; Thomas Stamminger
Inhibitors of human cytomegalovirus replication drastically reduce the activity of the viral protein kinase pUL97.
The Journal of general virology 2001;82(Pt 6):1439-50.
2000: Michael Winkler; T aus Dem Siepen; Thomas Stamminger
Functional interaction between pleiotropic transactivator pUL69 of human cytomegalovirus and the human homolog of yeast chromatin regulatory protein SPT6.
Journal of virology 2000;74(17):8053-64.
2000: Manfred Marschall; Martina Freitag; S Weiler; Gabriele Sorg; Thomas Stamminger
Recombinant green fluorescent protein-expressing human cytomegalovirus as a tool for screening antiviral agents.
Antimicrobial agents and chemotherapy 2000;44(6):1588-97.
2000: Heike Hofmann; S Flöss; Thomas Stamminger
Covalent modification of the transactivator protein IE2-p86 of human cytomegalovirus by conjugation to the ubiquitin-homologous proteins SUMO-1 and hSMT3b.
Journal of virology 2000;74(6):2510-24.
2000: S Flöss; Thomas Stamminger
Analysis of Protein-DNA Interactions During Cytomegalovirus Infection.
Methods in molecular medicine 2000;33():95-114.
1999: Gabriele Sorg; Thomas Stamminger
Mapping of nuclear localization signals by simultaneous fusion to green fluorescent protein and to beta-galactosidase.
BioTechniques 1999;26(5):858-62.
1999: H Einsele; H Herbart; T Bock; C Müller; Bernhard Fleckenstein; M Mach; Thomas Stamminger; Gerhard Jahn; Christian Sinzger; U Koszinowski; U Meyer-König; T Mertens; Bodo Plachter; M J Reddehase; Christian A Schmidt
[Recommendations for the diagnosis and therapy of cytomegalovirus infection after stem-cell transplantation. The Research Alliance on the Complications of Organ Transplantation due to Herpes Viruses].
Deutsche medizinische Wochenschrift (1946) 1999;124(16):501-6.
1998: Gabriele Sorg; Thomas Stamminger
Strong conservation of the constitutive activity of the IE1/2 transcriptional control region in wild-type strains of human cytomegalovirus.
The Journal of general virology 1998;79 ( Pt 12)():3039-47.
1998: Stefan Pöhlmann; S Flöss; P O Ilyinskii; Thomas Stamminger; Frank Kirchhoff
Sequences just upstream of the simian immunodeficiency virus core enhancer allow efficient replication in the absence of NF-kappaB and Sp1 binding elements.
Journal of virology 1998;72(7):5589-98.
1997: S Gebert; S Schmolke; Gabriele Sorg; S Flöss; Bodo Plachter; Thomas Stamminger
The UL84 protein of human cytomegalovirus acts as a transdominant inhibitor of immediate-early-mediated transactivation that is able to prevent viral replication.
Journal of virology 1997;71(9):7048-60.
1996: M Winkler; Thomas Stamminger
A specific subform of the human cytomegalovirus transactivator protein pUL69 is contained within the tegument of virus particles.
Journal of virology 1996;70(12):8984-7.
1996: F Korioth; G G Maul; Bodo Plachter; Thomas Stamminger; J Frey
The nuclear domain 10 (ND10) is disrupted by the human cytomegalovirus gene product IE1.
Experimental cell research 1996;229(1):155-8.
1995: D Lang; S Gebert; H Arlt; Thomas Stamminger
Functional interaction between the human cytomegalovirus 86-kilodalton IE2 protein and the cellular transcription factor CREB.
Journal of virology 1995;69(10):6030-7.
1994: D Lang; Thomas Stamminger
Minor groove contacts are essential for an interaction of the human cytomegalovirus IE2 protein with its DNA target.
Nucleic acids research 1994;22(16):3331-8.
1994: H Arlt; D Lang; S Gebert; Thomas Stamminger
Identification of binding sites for the 86-kilodalton IE2 protein of human cytomegalovirus within an IE2-responsive viral early promoter.
Journal of virology 1994;68(7):4117-25.
1994: M Winkler; S A Rice; Thomas Stamminger
UL69 of human cytomegalovirus, an open reading frame with homology to ICP27 of herpes simplex virus, encodes a transactivator of gene expression.
Journal of virology 1994;68(6):3943-54.
1994: Thomas Stamminger; Bernhard Fleckenstein
[Current developments in antiviral chemotherapy. 3: Vidarabine, ganciclovir].
Fortschritte der Medizin 1994;112(12):172-3.
1994: Thomas Stamminger; Bernhard Fleckenstein
[Current developments in antiviral chemotherapy. 2: Acyclovir].
Fortschritte der Medizin 1994;112(11):159-60.
1994: Thomas Stamminger; Bernhard Fleckenstein
[Current developments in antiviral chemotherapy. 1: Principles and overview--amantadine].
Fortschritte der Medizin 1994;112(10):140-1.
1993: Bodo Plachter; W Britt; R Vornhagen; Thomas Stamminger; Gerhard Jahn
Analysis of proteins encoded by IE regions 1 and 2 of human cytomegalovirus using monoclonal antibodies generated against recombinant antigens.
Virology 1993;193(2):642-52.
1993: D Lang; Thomas Stamminger
The 86-kilodalton IE-2 protein of human cytomegalovirus is a sequence-specific DNA-binding protein that interacts directly with the negative autoregulatory response element located near the cap site of the IE-1/2 enhancer-promoter.
Journal of virology 1993;67(1):323-31.
1992: H Moch; D Lang; Thomas Stamminger
Strong trans activation of the human cytomegalovirus major immediate-early enhancer by p40tax of human T-cell leukemia virus type I via two repetitive tax-responsive sequence elements.
Journal of virology 1992;66(12):7346-54.
1992: D Lang; Helmut Fickenscher; Thomas Stamminger
Analysis of proteins binding to the proximal promoter region of the human cytomegalovirus IE-1/2 enhancer/promoter reveals both consensus and aberrant recognition sequences for transcription factors Sp1 and CREB.
Nucleic acids research 1992;20(13):3287-95.
1991: R Lehner; Thomas Stamminger; Michael Mach
Comparative sequence analysis of human cytomegalovirus strains.
Journal of clinical microbiology 1991;29(11):2494-502.
1991: E Puchtler; Thomas Stamminger
An inducible promoter mediates abundant expression from the immediate-early 2 gene region of human cytomegalovirus at late times after infection.
Journal of virology 1991;65(11):6301-6.
1991: Thomas Stamminger; E Puchtler; Bernhard Fleckenstein
Discordant expression of the immediate-early 1 and 2 gene regions of human cytomegalovirus at early times after infection involves posttranscriptional processing events.
Journal of virology 1991;65(5):2273-82.
1990: S A Rudolph; Thomas Stamminger; Gerhard Jahn
Transcriptional analysis of the eight-kilobase mRNA encoding the major capsid protein of human cytomegalovirus.
Journal of virology 1990;64(10):5167-72.
1990: Thomas Stamminger; Bernhard Fleckenstein
Immediate-early transcription regulation of human cytomegalovirus.
Current topics in microbiology and immunology 1990;154():3-19.
1990: Thomas Stamminger; Helmut Fickenscher; Bernhard Fleckenstein
Cell type-specific induction of the major immediate early enhancer of human cytomegalovirus by cyclic AMP.
The Journal of general virology 1990;71 ( Pt 1)():105-13.
1989: Michael Mach; Thomas Stamminger; Gerhard Jahn
Human cytomegalovirus: recent aspects from molecular biology.
The Journal of general virology 1989;70 ( Pt 12)():3117-46.
1989: Helmut Fickenscher; Thomas Stamminger; R Rüger; Bernhard Fleckenstein
The role of a repetitive palindromic sequence element in the human cytomegalovirus major immediate early enhancer.
The Journal of general virology 1989;70 ( Pt 1)():107-23.