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Bethel Stannard

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Shoshana Yakar; Nomeli P Nunez; Patricia Pennisi; Pnina Brodt; Hui Sun; Lucia Fallavollita; Hong Zhao; Louis Scavo; Ruslan Novosyadlyy; Naamit Kurshan; Bethel Stannard; Joyce East-Palmer; Nicole C P Smith; Susan N Perkins; Robin Fuchs-Young; J Carl Barrett; Stephen D Hursting; Derek LeRoith
Increased tumor growth in mice with diet-induced obesity: impact of ovarian hormones.
Shoshana Yakar; Hui Sun; Hong Zhao; Patricia Pennisi; Yuka Toyoshima; Jennifer Setser; Bethel Stannard; Louis Scavo; Derek LeRoith
Metabolic effects of IGF-I deficiency: lessons from mouse models.
Martin Haluzik; Carlo Colombo; Oksana Gavrilova; Streamson Chua Jr.; Nicole Wolf; Min Chen; Bethel Stannard; Kelly R Dietz; Derek Le Roith; Marc L Reitman
Genetic background (C57BL/6J versus FVB/N) strongly influences the severity of diabetes and insulin resistance in ob/ob mice.

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All Publications

2006: Shoshana Yakar; Nomeli P Nunez; Patricia Pennisi; Pnina Brodt; Hui Sun; Lucia Fallavollita; Hong Zhao; Louis Scavo; Ruslan Novosyadlyy; Naamit Kurshan; Bethel Stannard; Joyce East-Palmer; Nicole C P Smith; Susan N Perkins; Robin Fuchs-Young; J Carl Barrett; Stephen D Hursting; Derek LeRoith
Increased tumor growth in mice with diet-induced obesity: impact of ovarian hormones.
Endocrinology 2006;147(12):5826-34.
2005: Shoshana Yakar; Hui Sun; Hong Zhao; Patricia Pennisi; Yuka Toyoshima; Jennifer Setser; Bethel Stannard; Louis Scavo; Derek LeRoith
Metabolic effects of IGF-I deficiency: lessons from mouse models.
Pediatric endocrinology reviews : PER 2005;3(1):11-9.
2004: Martin Haluzik; Carlo Colombo; Oksana Gavrilova; Streamson Chua Jr.; Nicole Wolf; Min Chen; Bethel Stannard; Kelly R Dietz; Derek Le Roith; Marc L Reitman
Genetic background (C57BL/6J versus FVB/N) strongly influences the severity of diabetes and insulin resistance in ob/ob mice.
Endocrinology 2004;145(7):3258-64.
2004: Lisa Héron-Milhavet; Yang Xue-Jun; Susan J Vannucci; Teresa L Wood; Lisa B Willing; Bethel Stannard; Catalina Hernandez-Sanchez; Charles Mobbs; Anne Virsolvy; Derek LeRoith
Protection against hypoxic-ischemic injury in transgenic mice overexpressing Kir6.2 channel pore in forebrain.
Molecular and cellular neurosciences 2004;25(4):585-93.
2004: Shoshana Yakar; Jennifer Setser; Hong Zhao; Bethel Stannard; Martin Haluzik; Vaida Glatt; Mary L Bouxsein; John J Kopchick; Derek LeRoith
Inhibition of growth hormone action improves insulin sensitivity in liver IGF-1-deficient mice.
The Journal of clinical investigation 2004;113(1):96-105.
2003: Hyunsook Kim; Martin Haluzik; Zeenat Asghar; Daphne Yau; Jamie W Joseph; Ana M Fernandez; Marc L Reitman; Shoshana Yakar; Bethel Stannard; Lisa Heron-Milhavet; Michael B Wheeler; Derek LeRoith
Peroxisome proliferator-activated receptor-alpha agonist treatment in a transgenic model of type 2 diabetes reverses the lipotoxic state and improves glucose homeostasis.
Diabetes 2003;52(7):1770-8.
2002: Patricia Pennisi; Valarie Barr; Nomeli P Nunez; Bethel Stannard; Derek Le Roith
Reduced expression of insulin-like growth factor I receptors in MCF-7 breast cancer cells leads to a more metastatic phenotype.
Cancer research 2002;62(22):6529-37.
2002: Ana M Fernández; Joëlle Dupont; Roger P Farrar; Sukho Lee; Bethel Stannard; Derek Le Roith
Muscle-specific inactivation of the IGF-I receptor induces compensatory hyperplasia in skeletal muscle.
The Journal of clinical investigation 2002;109(3):347-55.
2001: C Hernández-Sánchez; Anthony Basile; Irina Fedorova; H Arima; Bethel Stannard; Ana M Fernandez; Y Ito; Derek LeRoith
Mice transgenically overexpressing sulfonylurea receptor 1 in forebrain resist seizure induction and excitotoxic neuron death.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(6):3549-54.
1999: Shoshana Yakar; JL Liu; Bethel Stannard; A Butler; D Accili; Brian Sauer; Derek LeRoith
Normal growth and development in the absence of hepatic insulin-like growth factor I.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(13):7324-9.
1998: Y Okubo; VA Blakesley; Bethel Stannard; J Silvio Gutkind; Derek Le Roith
Insulin-like growth factor-I inhibits the stress-activated protein kinase/c-Jun N-terminal kinase.
The Journal of biological chemistry 1998;273(40):25961-6.
1998: VA Blakesley; AP Koval; Bethel Stannard; AG Scrimgeour; Derek LeRoith
Replacement of tyrosine 1251 in the carboxyl terminus of the insulin-like growth factor-I receptor disrupts the actin cytoskeleton and inhibits proliferation and anchorage-independent growth.
The Journal of biological chemistry 1998;273(29):18411-22.
1997: VA Blakesley; D Beitner-Johnson; J R Van Brocklyn; S Rani; Z Shen-Orr; Bethel Stannard; Sarah Spiegel; Derek LeRoith
Sphingosine 1-phosphate stimulates tyrosine phosphorylation of Crk.
The Journal of biological chemistry 1997;272(26):16211-5.
1997: AG Scrimgeour; VA Blakesley; Bethel Stannard; Derek LeRoith
Mitogen-activated protein kinase and phosphatidylinositol 3-kinase pathways are not sufficient for insulin-like growth factor I-induced mitogenesis and tumorigenesis.
Endocrinology 1997;138(6):2552-8.
1997: VA Blakesley; Bethel Stannard; Thea Kalebic; Lee Helman; Derek LeRoith
Role of the IGF-I receptor in mutagenesis and tumor promotion.
The Journal of endocrinology 1997;152(3):339-44.
1996: D Beitner-Johnson; VA Blakesley; Z Shen-Orr; M Jimenez; Bethel Stannard; L M Wang; J Pierce; Derek LeRoith
The proto-oncogene product c-Crk associates with insulin receptor substrate-1 and 4PS. Modulation by insulin growth factor-I (IGF) and enhanced IGF-I signaling.
The Journal of biological chemistry 1996;271(16):9287-90.
1996: VA Blakesley; Thea Kalebic; Lee Helman; Bethel Stannard; T N Faria; Charles T Roberts; Derek LeRoith
Tumorigenic and mitogenic capacities are reduced in transfected fibroblasts expressing mutant insulin-like growth factor (IGF)-I receptors. The role of tyrosine residues 1250, 1251, and 1316 in the carboxy-terminus of the IGF-I receptor.
Endocrinology 1996;137(2):410-7.
1995: Bethel Stannard; VA Blakesley; H Kato; Charles T Roberts; Derek LeRoith
Single tyrosine substitution in the insulin-like growth factor I receptor inhibits ligand-induced receptor autophosphorylation and internalization, but not mitogenesis.
Endocrinology 1995;136(11):4918-24.
1994: T N Faria; VA Blakesley; H Kato; Bethel Stannard; Derek LeRoith; Charles T Roberts
Role of the carboxyl-terminal domains of the insulin and insulin-like growth factor I receptors in receptor function.
The Journal of biological chemistry 1994;269(19):13922-8.
1994: H Kato; T N Faria; Bethel Stannard; Charles T Roberts; Derek LeRoith
Essential role of tyrosine residues 1131, 1135, and 1136 of the insulin-like growth factor-I (IGF-I) receptor in IGF-I action.
Molecular endocrinology (Baltimore, Md.) 1994;8(1):40-50.
1993: H Domené; K Krishnamurthi; R Eshet; I Gilad; Z Laron; I Koch; Bethel Stannard; Fernando Cassorla; Charles T Roberts; Derek LeRoith
Growth hormone (GH) stimulates insulin-like growth factor-I (IGF-I) and IGF-I-binding protein-3, but not GH receptor gene expression in livers of juvenile rats.
Endocrinology 1993;133(2):675-82.
1993: H Kato; T N Faria; Bethel Stannard; R Levy-Toledano; Simeon I Taylor; Charles T Roberts; Derek LeRoith
Paradoxical biological effects of overexpressed insulin-like growth factor-1 receptors in Chinese hamster ovary cells.
Journal of cellular physiology 1993;156(1):145-52.
1993: H Kato; T N Faria; Bethel Stannard; Charles T Roberts; Derek LeRoith
Role of tyrosine kinase activity in signal transduction by the insulin-like growth factor-I (IGF-I) receptor. Characterization of kinase-deficient IGF-I receptors and the action of an IGF-I-mimetic antibody (alpha IR-3).
The Journal of biological chemistry 1993;268(4):2655-61.
1992: H Werner; M A Bach; Bethel Stannard; Charles T Roberts; Derek LeRoith
Structural and functional analysis of the insulin-like growth factor I receptor gene promoter.
Molecular endocrinology (Baltimore, Md.) 1992;6(10):1545-58.
1992: Derek LeRoith; M McGuinness; J Shemer; Bethel Stannard; F Lanau; T N Faria; H Kato; H Werner; Martin Adamo; Charles T Roberts
Insulin-like growth factors.
Biological signals 1992;1(4):173-81.
1991: H Werner; Bethel Stannard; M A Bach; Charles T Roberts; Derek LeRoith
Regulation of insulin-like growth factor I receptor gene expression in normal and pathological states.
Advances in experimental medicine and biology 1991;293():263-72.
1990: H Werner; Z Shen-Orr; Bethel Stannard; B Burguera; Charles T Roberts; Derek LeRoith
Experimental diabetes increases insulinlike growth factor I and II receptor concentration and gene expression in kidney.
Diabetes 1990;39(12):1490-7.
1990: B Burguera; H Werner; M Sklar; Z Shen-Orr; Bethel Stannard; Charles T Roberts; S P Nissley; Stephen J Vore; JF Caro; Derek LeRoith
Liver regeneration is associated with increased expression of the insulin-like growth factor-II/mannose-6-phosphate receptor.
Molecular endocrinology (Baltimore, Md.) 1990;4(10):1539-45.
1990: H Werner; Bethel Stannard; M A Bach; Derek LeRoith; Charles T Roberts
Cloning and characterization of the proximal promoter region of the rat insulin-like growth factor I (IGF-I) receptor gene.
Biochemical and biophysical research communications 1990;169(3):1021-7.
1990: P W Gyves; N Gesundheit; N R Thotakura; Bethel Stannard; George Decherney; Bruce D Weintraub
Changes in the sialylation and sulfation of secreted thyrotropin in congenital hypothyroidism.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(10):3792-6.
1989: Bethel Stannard; N Gesundheit; N R Thotakura; P W Gyves; C Ronin; Bruce D Weintraub
Differential effect of inhibitors of oligosaccharide processing on the secretion of thyrotropin from dispersed rodent pituitary cells.
Biochemical and biophysical research communications 1989;165(2):788-94.
1989: N Gesundheit; P W Gyves; George Decherney; Bethel Stannard; R L Winston; Bruce D Weintraub
Characterization and charge distribution of the asparagine-linked oligosaccharides on secreted mouse thyrotropin and free alpha-subunits.
Endocrinology 1989;124(6):2967-77.
1989: P W Gyves; N Gesundheit; Bethel Stannard; George Decherney; Bruce D Weintraub
Alterations in the glycosylation of secreted thyrotropin during ontogenesis. Analysis of sialylated and sulfated oligosaccharides.
The Journal of biological chemistry 1989;264(11):6104-10.
1988: Bethel Stannard; N Gesundheit; C Ronin; J Burnside; Bruce D Weintraub
Differential carbohydrate processing and secretion of thyrotropin and free alpha subunit. Effects of 1-deoxynojirimycin.
The Journal of biological chemistry 1988;263(17):8309-17.
1985: C Ronin; Bethel Stannard; Bruce D Weintraub
Differential processing and regulation of thyroid-stimulating hormone subunit carbohydrate chains in thyrotropic tumors and in normal and hypothyroid pituitaries.
Biochemistry 1985;24(20):5626-31.
1985: Bruce D Weintraub; Bethel Stannard; J A Magner; C Ronin; T Taylor; L Joshi; R B Constant; M M Menezes-Ferreira; P Petrick; N Gesundheit
Glycosylation and posttranslational processing of thyroid-stimulating hormone: clinical implications.
Recent progress in hormone research 1985;41():577-606.
1984: C Ronin; Bethel Stannard; I L Rosenbloom; J A Magner; Bruce D Weintraub
Glycosylation and processing of high-mannose oligosaccharides of thyroid-stimulating hormone subunits: comparison to nonsecretory cell glycoproteins.
Biochemistry 1984;23(20):4503-10.