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Kwangseog Ahn

Research Profile

Chemicals & Drugs

Anatomy

Living Beings

Cytomegalovirus

Phenomena

Protein Binding

Physiology

Disorders

Cytomegalovirus Infections

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Publications

TOP 3
Youngkyun Kim; Sanghyun Lee; JIN HYUN AHN; Donghyun Kim; Sungchul Kim; Kwangseog Ahn
Human cytomegalovirus clinical strain-specific microRNA miR-UL148D targets the human chemokine RANTES during infection.
Sungchul Kim; V Narry Kim; Youngkyun Kim; Young-Eui Kim; Young-Kook Kim; Sanghyun Lee; Stanley R Riddell; Jinwook Shin; efstratios stratikos; JIN HYUN AHN; Irini Evnouchidou; Donghyun Kim; Kwangseog Ahn
Human cytomegalovirus microRNA miR-US4-1 inhibits CD8(+) T cell responses by targeting the aminopeptidase ERAP1.
Kwangmin Cho; Sunglim Cho; Kwonyoon Kang; Seongman Kang; Sungwook Lee; Seong-Ok Lee; Changhoon Oh; Jae Wook Ryoo; Kwangseog Ahn
Redox-regulated peptide transfer from the transporter associated with antigen processing to major histocompatibility complex class I molecules by protein disulfide isomerase.

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All Publications

2012: Youngkyun Kim; Sanghyun Lee; JIN HYUN AHN; Donghyun Kim; Sungchul Kim; Kwangseog Ahn
Human cytomegalovirus clinical strain-specific microRNA miR-UL148D targets the human chemokine RANTES during infection.
PLoS pathogens 2012;8(3):e1002577.
2011: Sungchul Kim; V Narry Kim; Youngkyun Kim; Young-Eui Kim; Young-Kook Kim; Sanghyun Lee; Stanley R Riddell; Jinwook Shin; efstratios stratikos; JIN HYUN AHN; Irini Evnouchidou; Donghyun Kim; Kwangseog Ahn
Human cytomegalovirus microRNA miR-US4-1 inhibits CD8(+) T cell responses by targeting the aminopeptidase ERAP1.
Nature immunology 2011;12(10):984-91.
2011: Kwangmin Cho; Sunglim Cho; Kwonyoon Kang; Seongman Kang; Sungwook Lee; Seong-Ok Lee; Changhoon Oh; Jae Wook Ryoo; Kwangseog Ahn
Redox-regulated peptide transfer from the transporter associated with antigen processing to major histocompatibility complex class I molecules by protein disulfide isomerase.
Antioxidants & redox signaling 2011;15(3):621-33.
2011: Youngsoo Jun; Kwangseog Ahn
Tmp21, a novel MHC-I interacting protein, preferentially binds to Β2-microglobulin-free MHC-I heavy chains.
BMB reports 2011;44(6):369-74.
2011: Sunglim Cho; Jeongmin Ryoo; Youngsoo Jun; Kwangseog Ahn
Receptor-mediated ER export of human MHC class I molecules is regulated by the C-terminal single amino acid.
Traffic (Copenhagen, Denmark) 2011;12(1):42-55.
2010: Seong-Ok Lee; Kwangmin Cho; Sunglim Cho; Ilkwon Kim; Changhoon Oh; Kwangseog Ahn
Protein disulphide isomerase is required for signal peptide peptidase-mediated protein degradation.
The EMBO journal 2010;29(2):363-75.
2009: Eunkyung Kim; Heechun Kwak; Kwangseog Ahn
Cytosolic aminopeptidases influence MHC class I-mediated antigen presentation in an allele-dependent manner.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(11):7379-87.
2009: Kwonyoon Kang; Boyoun Park; Changhoon Oh; Kwangmin Cho; Kwangseog Ahn
A role for protein disulfide isomerase in the early folding and assembly of MHC class I molecules.
Antioxidants & redox signaling 2009;11(10):2553-61.
2009: Sungwook Lee; Boyoun Park; Kwonyoon Kang; Kwangseog Ahn
Redox-regulated export of the major histocompatibility complex class I-peptide complexes from the endoplasmic reticulum.
Molecular biology of the cell 2009;20(14):3285-94.
2009: Youngkyun Kim; Kwonyoon Kang; Ilkwon Kim; Yoon Jeong Lee; Changhoon Oh; Jae Wook Ryoo; Eunae Jeong; Kwangseog Ahn
Molecular mechanisms of MHC class I-antigen processing: redox considerations.
Antioxidants & redox signaling 2009;11(4):907-36.
2008: Kwangseog Ahn; Susan R Woskie; Louis DiBerardinis; Michael J Ellenbecker
A review of published quantitative experimental studies on factors affecting laboratory fume hood performance.
Journal of occupational and environmental hygiene 2008;5(11):735-53.
2008: Youngkyun Kim; Boyoun Park; Sunglim Cho; Jinwook Shin; Kwangmin Cho; youngsoo jun; Kwangseog Ahn
Human cytomegalovirus UL18 utilizes US6 for evading the NK and T-cell responses.
PLoS pathogens 2008;4(8):e1000123.
2008: Taehyeung Kim; Dong Ho Lee; Kwangseog Ahn; Hyunchul Ha; Heechang Park; Cheng Xu Piao; Xiaoyu Li; Jeoungyoon Seo
Characteristics of rain penetration through a gravity ventilator used for natural ventilation.
The Annals of occupational hygiene 2008;52(1):35-44.
2006: Boyoun Park; Sungwook Lee; Eunkyung Kim; Kwangmin Cho; Stanley R Riddell; Sunglim Cho; Kwangseog Ahn
Redox regulation facilitates optimal peptide selection by MHC class I during antigen processing.
Cell 2006;127(2):369-82.
2006: Jinwook Shin; Boyoun Park; Sungwook Lee; Youngkyun Kim; Bonita J Biegalke; Seongman Kang; Kwangseog Ahn
A short isoform of human cytomegalovirus US3 functions as a dominant negative inhibitor of the full-length form.
Journal of virology 2006;80(11):5397-404.
2005: Seong-Ok Lee; Sujin Hwang; Junghyun Park; Boyoun Park; Bong-Suk Jin; Sungwook Lee; Eunkyung Kim; Sunglim Cho; Youngkyun Kim; Kwangmin Cho; Jinwook Shin; Kwangseog Ahn
Functional dissection of HCMV US11 in mediating the degradation of MHC class I molecules.
Biochemical and biophysical research communications 2005;330(4):1262-7.
2005: nupur tewari pande; Colin Powers; Kwangseog Ahn; Klaus J Frueh
Rhesus cytomegalovirus contains functional homologues of US2, US3, US6, and US11.
Journal of virology 2005;79(9):5786-98.
2005: Bong-Suk Jin; Lee Won-Kyu; Kwangseog Ahn; Myung Kyu Lee; Yeon Gyu Yu
High-throughput screening method of inhibitors that block the interaction between 2 helical regions of HIV-1 gp41.
Journal of biomolecular screening 2005;10(1):13-9.
2004: Sunoh Kim; Taehyun Kim; Kwangseog Ahn; Woo-Kyu Park; Seung-Yeol Nah; Hyewhon Rhim
Ginsenoside Rg3 antagonizes NMDA receptors through a glycine modulatory site in rat cultured hippocampal neurons.
Biochemical and biophysical research communications 2004;323(2):416-24.
2004: Jinwook Shin; Boyoun Park; Sunglim Cho; Sungwook Lee; Youngkyun Kim; Seong-Ok Lee; Kwangmin Cho; Sunray Lee; Bong-Suk Jin; JIN HYUN AHN; Eui-Ju Choi; Kwangseog Ahn
Promyelocytic leukemia is a direct inhibitor of SAPK2/p38 mitogen-activated protein kinase.
The Journal of biological chemistry 2004;279(39):40994-1003.
2004: Hyunho Kim; Woocho Jeong; Kwangseog Ahn; Curie Ahn; Seongman Kang
Siah-1 interacts with the intracellular region of polycystin-1 and affects its stability via the ubiquitin-proteasome pathway.
Journal of the American Society of Nephrology : JASN 2004;15(8):2042-9.
2004: Gyu Man Park; Sunray Lee; Boyoun Park; Eunkyung Kim; Jinwook Shin; Kwangmin Cho; Kwangseog Ahn
Soluble HLA-G generated by proteolytic shedding inhibits NK-mediated cell lysis.
Biochemical and biophysical research communications 2004;313(3):606-11.
2004: Boyoun Park; Youngkyun Kim; Jinwook Shin; Sungwook Lee; Kwangmin Cho; Klaus J Frueh; Sunray Lee; Kwangseog Ahn
Human cytomegalovirus inhibits tapasin-dependent peptide loading and optimization of the MHC class I peptide cargo for immune evasion.
Immunity 2004;20(1):71-85.
2003: Boyoun Park; Kwangseog Ahn
An essential function of tapasin in quality control of HLA-G molecules.
The Journal of biological chemistry 2003;278(16):14337-45.
2003: Sungwook Lee; Boyoun Park; Kwangseog Ahn
Determinant for endoplasmic reticulum retention in the luminal domain of the human cytomegalovirus US3 glycoprotein.
Journal of virology 2003;77(3):2147-56.
2003: Boyoun Park; Sungwook Lee; Euijae Kim; Kwangseog Ahn
A single polymorphic residue within the peptide-binding cleft of MHC class I molecules determines spectrum of tapasin dependence.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(2):961-8.
2002: Sook-Kyung Chang; Boyoun Park; Jinwook Shin; JIN HYUN AHN; Ik-Hwan Kim; Kwangseog Ahn
Proto-oncogene PML enhances antigen presentation by MHC class I molecules in human lung cancer cells.
Molecules and cells 2002;14(1):130-5.
2002: Sunoh Kim; Kwangseog Ahn; Tae H Oh; Seung-Yeol Nah; Hyewhon Rhim
Inhibitory effect of ginsenosides on NMDA receptor-mediated signals in rat hippocampal neurons.
Biochemical and biophysical research communications 2002;296(2):247-54.
2002: Boyoun Park; Hokyung Oh; Sungwook Lee; Yangsook Song; Jinwook Shin; Young Chul Sung; Sue-Yun Hwang; Kwangseog Ahn
The MHC class I homolog of human cytomegalovirus is resistant to down-regulation mediated by the unique short region protein (US)2, US3, US6, and US11 gene products.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(7):3464-9.
2002: Mirim Jin; Junghyun Park; Sungwook Lee; Boyoun Park; Jinwook Shin; Ki-Joon Song; Tae-In Ahn; Sue-Yun Hwang; Byung-Yoon Ahn; Kwangseog Ahn
Hantaan virus enters cells by clathrin-dependent receptor-mediated endocytosis.
Virology 2002;294(1):60-9.
2001: J H Park; H W Kwon; H K Chung; Ik-Hwan Kim; Kwangseog Ahn; Eui-Ju Choi; Ira Pastan; M Choe
A divalent recombinant immunotoxin formed by a disulfide bond between the extension peptide chains.
Molecules and cells 2001;12(3):398-402.
2001: Boyoun Park; Sungwook Lee; E Kim; S Chang; M Jin; Kwangseog Ahn
The truncated cytoplasmic tail of HLA-G serves a quality-control function in post-ER compartments.
Immunity 2001;15(2):213-24.
2000: Sungwook Lee; J Yoon; Boyoun Park; youngsoo jun; Mirim Jin; Ha-Chin Sung; I H Kim; Seongman Kang; E J Choi; Byung-Yoon Ahn; Kwangseog Ahn
Structural and functional dissection of human cytomegalovirus US3 in binding major histocompatibility complex class I molecules.
Journal of virology 2000;74(23):11262-9.
2000: Bong-Suk Jin; JR Ryu; Kwangseog Ahn; Yeon Gyu Yu
Design of a peptide inhibitor that blocks the cell fusion mediated by glycoprotein 41 of human immunodeficiency virus type 1.
AIDS research and human retroviruses 2000;16(17):1797-804.
2000: Sung-Jo Kim; H Park; Jeong-Kook Kim; Ji Youl Lee; Kwangseog Ahn; M Choe; Yun-Jaie Choi; Joon Kim
Random changes of amino acid residues with expected frequency by saturated point mutagenesis.
Molecules and cells 2000;10(2):232-5.
2000: Hee-Sae Park; E Park; Mi-Sung Kim; Kwangseog Ahn; Ick Young Kim; Eui-Ju Choi
Selenite inhibits the c-Jun N-terminal kinase/stress-activated protein kinase (JNK/SAPK) through a thiol redox mechanism.
The Journal of biological chemistry 2000;275(4):2527-31.
2000: youngsoo jun; Euijae Kim; M Jin; Ha-Chin Sung; H Han; D E Geraghty; Kwangseog Ahn
Human cytomegalovirus gene products US3 and US6 down-regulate trophoblast class I MHC molecules.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(2):805-11.
1999: Tae Soo Kim; Myeong-Hee Yu; Youn Wook Chung; Joon Kim; Eui-Ju Choi; Kwangseog Ahn; Ick Young Kim
Fetal mouse selenophosphate synthetase 2 (SPS2): biological activities of mutant forms in Escherichia coli.
Molecules and cells 1999;9(4):422-8.
1999: K S Bok; Hyangshuk Rhim; Young Do Yoo; E Choi; Kwangseog Ahn; Ik-Hwan Kim; Seongman Kang
Expanded polyglutamine tract itself induces cell death in cultured cells.
Molecules and cells 1999;9(4):398-402.
1997: Kwangseog Ahn; A Gruhler; B Galocha; T R Jones; Emmanuel J H J Wiertz; H L Ploegh; PA Peterson; Y Yang; Klaus J Frueh
The ER-luminal domain of the HCMV glycoprotein US6 inhibits peptide translocation by TAP.
Immunity 1997;6(5):613-21.