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Robyn Starr

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Robyn Starr; Martina Fuchsberger; Lei Shong Lau; Adam P Uldrich; Ankita Goradia; Tracy A Willson; Anne M Verhagen; Warren S Alexander; Mark J Smyth
SOCS-1 binding to tyrosine 441 of IFN-gamma receptor subunit 1 contributes to the attenuation of IFN-gamma signaling in vivo.
Hayley A Croom; David J Izon; Mark M Chong; David J Curtis; Andrew W Roberts; Thomas W H Kay; Douglas J Hilton; Warren S Alexander; Robyn Starr
Perturbed thymopoiesis in vitro in the absence of suppressor of cytokine signalling 1 and 3.
Elena Tucker; Kristy O'Donnell; Martina Fuchsberger; Adrienne A Hilton; Donald Metcalf; Kylie Greig; Natalie Sims; Julian M W Quinn; Warren S Alexander; Douglas J Hilton; Benjamin T Kile; David M Tarlinton; Robyn Starr
A novel mutation in the Nfkb2 gene generates an NF-kappa B2 "super repressor".

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2009: Robyn Starr; Martina Fuchsberger; Lei Shong Lau; Adam P Uldrich; Ankita Goradia; Tracy A Willson; Anne M Verhagen; Warren S Alexander; Mark J Smyth
SOCS-1 binding to tyrosine 441 of IFN-gamma receptor subunit 1 contributes to the attenuation of IFN-gamma signaling in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(7):4537-44.
2008: Hayley A Croom; David J Izon; Mark M Chong; David J Curtis; Andrew W Roberts; Thomas W H Kay; Douglas J Hilton; Warren S Alexander; Robyn Starr
Perturbed thymopoiesis in vitro in the absence of suppressor of cytokine signalling 1 and 3.
Molecular immunology 2008;45(10):2888-96.
2007: Elena Tucker; Kristy O'Donnell; Martina Fuchsberger; Adrienne A Hilton; Donald Metcalf; Kylie Greig; Natalie Sims; Julian M W Quinn; Warren S Alexander; Douglas J Hilton; Benjamin T Kile; David M Tarlinton; Robyn Starr
A novel mutation in the Nfkb2 gene generates an NF-kappa B2 "super repressor".
Journal of immunology (Baltimore, Md. : 1950) 2007;179(11):7514-22.
2007: Christine Brender; Gillian M Tannahill; Brendan J Jenkins; Joel Fletcher; Ruth Columbus; Christiaan J M Saris; Matthias Ernst; Nicos A Nicola; Douglas J Hilton; Warren S Alexander; Robyn Starr
Suppressor of cytokine signaling 3 regulates CD8 T-cell proliferation by inhibition of interleukins 6 and 27.
Blood 2007;110(7):2528-36.
2006: Gayle M Davey; William R Heath; Robyn Starr
SOCS1: a potent and multifaceted regulator of cytokines and cell-mediated inflammation.
Tissue antigens 2006;67(1):1-9.
2006: Jennifer E Fenner; Robyn Starr; Ann L Cornish; Jian-Guo Zhang; Donald Metcalf; Robert D Schreiber; Kathleen Sheehan; Douglas J Hilton; Warren S Alexander; Paul J Hertzog
Suppressor of cytokine signaling 1 regulates the immune response to infection by a unique inhibition of type I interferon activity.
Nature immunology 2006;7(1):33-9.
2005: Gayle M Davey; Robyn Starr; Ann L Cornish; J Theodore Burghardt; Warren S Alexander; Francis R Carbone; Charles D Surh; William R Heath
SOCS-1 regulates IL-15-driven homeostatic proliferation of antigen-naive CD8 T cells, limiting their autoimmune potential.
The Journal of experimental medicine 2005;202(8):1099-108.
2004: Christine Brender; Ruth Columbus; Donald Metcalf; Emanuela Handman; Robyn Starr; Nick Huntington; David M Tarlinton; Niels Ødum; Sandra E Nicholson; Nicos A Nicola; Douglas J Hilton; Warren S Alexander
SOCS5 is expressed in primary B and T lymphoid cells but is dispensable for lymphocyte production and function.
Molecular and cellular biology 2004;24(13):6094-103.
2003: Robyn Starr; Douglas J Hilton
Defining control: regulation of dendritic cell activation and immune homeostasis by SOCS1.
Immunity 2003;19(3):308-9.
2003: Ann L Cornish; Mark M W Chong; Gayle M Davey; Rima Darwiche; Nicos A Nicola; Douglas J Hilton; Thomas W H Kay; Robyn Starr; Warren S Alexander
Suppressor of cytokine signaling-1 regulates signaling in response to interleukin-2 and other gamma c-dependent cytokines in peripheral T cells.
The Journal of biological chemistry 2003;278(25):22755-61.
2003: Mark M W Chong; Ann L Cornish; Rima Darwiche; Edouard G Stanley; Jared F Purton; Dale I Godfrey; Douglas J Hilton; Robyn Starr; Warren S Alexander; Thomas W H Kay
Suppressor of cytokine signaling-1 is a critical regulator of interleukin-7-dependent CD8+ T cell differentiation.
Immunity 2003;18(4):475-87.
2003: Ann L Cornish; Gayle M Davey; Donald Metcalf; Jared F Purton; Jason E Corbin; Christopher J Greenhalgh; Rima Darwiche; Li Wu; Nicos A Nicola; Dale I Godfrey; William R Heath; Douglas J Hilton; Warren S Alexander; Robyn Starr
Suppressor of cytokine signaling-1 has IFN-gamma-independent actions in T cell homeostasis.
Journal of immunology (Baltimore, Md. : 1950) 2003;170(2):878-86.
2002: Joanne L Eyles; Donald Metcalf; Michael J Grusby; Douglas J Hilton; Robyn Starr
Negative regulation of interleukin-12 signaling by suppressor of cytokine signaling-1.
The Journal of biological chemistry 2002;277(46):43735-40.
2002: Rachael Richardson; Robyn Starr; Leecia J L Angus; Douglas J Hilton
A somatic cell genetic system for dissecting hemopoietic cytokine signal transduction.
The Journal of biological chemistry 2002;277(28):25624-30.
2002: Danielle L Krebs; Rachel Uren; Donald Metcalf; Steven Rakar; Jian-Guo Zhang; Robyn Starr; David P De Souza; Kathy Hanzinikolas; Jo Eyles; Lisa M Connolly; Richard J Simpson; Nicos A Nicola; Sandra E Nicholson; Manuel Baca; Douglas J Hilton; Warren S Alexander
SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation.
Molecular and cellular biology 2002;22(13):4567-78.
2002: Ann M Turnley; Robyn Starr; Perry F Bartlett
Failure of sensory neurons to express class I MHC is due to differential SOCS1 expression.
Journal of neuroimmunology 2002;123(1-2):35-40.
2001: Ann M Turnley; Robyn Starr; Perry F Bartlett
SOCS1 regulates interferon-gamma mediated sensory neuron survival.
Neuroreport 2001;12(16):3443-5.
2001: Jian-Guo Zhang; Donald Metcalf; Steven Rakar; M Asimakis; Christopher J Greenhalgh; Tracy A Willson; Robyn Starr; Sandra E Nicholson; W Carter; Warren S Alexander; Douglas J Hilton; Nicos A Nicola
The SOCS box of suppressor of cytokine signaling-1 is important for inhibition of cytokine action in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(23):13261-5.
2001: Geoffrey J Lindeman; Sergio Wittlin; H Lada; Matthew J Naylor; M Santamaria; Jian-Guo Zhang; Robyn Starr; Douglas J Hilton; Warren S Alexander; Christopher J Ormandy; Jane E Visvader
SOCS1 deficiency results in accelerated mammary gland development and rescues lactation in prolactin receptor-deficient mice.
Genes & development 2001;15(13):1631-6.
2001: M Brysha; Jian-Guo Zhang; P Bertolino; Jason E Corbin; Warren S Alexander; Nicos A Nicola; Douglas J Hilton; Robyn Starr
Suppressor of cytokine signaling-1 attenuates the duration of interferon gamma signal transduction in vitro and in vivo.
The Journal of biological chemistry 2001;276(25):22086-9.
2000: Donald Metcalf; Christopher J Greenhalgh; Elizabeth M Viney; Tracy A Willson; Robyn Starr; Nicos A Nicola; Douglas J Hilton; Warren S Alexander
Gigantism in mice lacking suppressor of cytokine signalling-2.
Nature 2000;405(6790):1069-73.
1999: Warren S Alexander; Robyn Starr; Donald Metcalf; Sandra E Nicholson; A Farley; Andrew G Elefanty; M Brysha; Benjamin T Kile; R Richardson; Manuel Baca; Jian-Guo Zhang; Tracy A Willson; Elizabeth M Viney; Naomi S Sprigg; Steven Rakar; Jason Corbin; Sandra Mifsud; Ladina DiRago; Dale Cary; Nicos A Nicola; Douglas J Hilton
Suppressors of cytokine signaling (SOCS): negative regulators of signal transduction.
Journal of leukocyte biology 1999;66(4):588-92.
1999: Warren S Alexander; Robyn Starr; Jennifer E Fenner; Clare L Scott; Emanuela Handman; Naomi S Sprigg; Jason E Corbin; Ann L Cornish; Rima Darwiche; Catherine M Owczarek; Thomas W H Kay; Nicos A Nicola; Paul J Hertzog; Donald Metcalf; Douglas J Hilton
SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine.
Cell 1999;98(5):597-608.
1999: Donald Metcalf; Warren S Alexander; Andrew G Elefanty; Nicos A Nicola; Douglas J Hilton; Robyn Starr; Sandra Mifsud; Ladina Di Rago
Aberrant hematopoiesis in mice with inactivation of the gene encoding SOCS-1.
Leukemia 1999;13(6):926-34.
1999: Sandra E Nicholson; Tracy A Willson; A Farley; Robyn Starr; Jian-Guo Zhang; Manuel Baca; Warren S Alexander; Donald Metcalf; Douglas J Hilton; Nicos A Nicola
Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechanisms for inhibition of LIF and IL-6 signal transduction.
The EMBO journal 1999;18(2):375-85.
1999: Nicos A Nicola; Sandra E Nicholson; Donald Metcalf; Jian-Guo Zhang; Manuel Baca; A Farley; Tracy A Willson; Robyn Starr; W Alexander; Douglas J Hilton
Negative regulation of cytokine signaling by the SOCS proteins.
Cold Spring Harbor symposia on quantitative biology 1999;64():397-404.
1998: Robyn Starr; Donald Metcalf; Andrew G Elefanty; M Brysha; Tracy A Willson; Nicos A Nicola; Douglas J Hilton; Warren S Alexander
Liver degeneration and lymphoid deficiencies in mice lacking suppressor of cytokine signaling-1.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(24):14395-9.
1998: Robyn Starr; Douglas J Hilton
SOCS: suppressors of cytokine signalling.
The international journal of biochemistry & cell biology 1998;30(10):1081-5.
1998: T E Adams; J A Hansen; Robyn Starr; Nicos A Nicola; Douglas J Hilton; Nils Billestrup
Growth hormone preferentially induces the rapid, transient expression of SOCS-3, a novel inhibitor of cytokine receptor signaling.
The Journal of biological chemistry 1998;273(3):1285-7.
1998: Douglas J Hilton; Rachael Richardson; Warren S Alexander; Elizabeth M Viney; Tracy A Willson; Naomi S Sprigg; Robyn Starr; Sandra E Nicholson; Donald Metcalf; Nicos A Nicola
Twenty proteins containing a C-terminal SOCS box form five structural classes.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(1):114-9.
1997: Robyn Starr; Ulrike Novak; T A Willson; Melissa Inglese; V Murphy; W S Alexander; D Metcalf; Nicos A Nicola; Douglas J Hilton; Matthias Ernst
Distinct roles for leukemia inhibitory factor receptor alpha-chain and gp130 in cell type-specific signal transduction.
The Journal of biological chemistry 1997;272(32):19982-6.
1997: Robyn Starr; Tracy A Willson; Elizabeth M Viney; L J Murray; J R Rayner; Brendan J Jenkins; Thomas J Gonda; Warren S Alexander; Donald Metcalf; Nicos A Nicola; Douglas J Hilton
A family of cytokine-inducible inhibitors of signalling.
Nature 1997;387(6636):917-21.
1996: S E Nicholson; Robyn Starr; Ulrike Novak; Douglas J Hilton; Judith E Layton
Tyrosine residues in the granulocyte colony-stimulating factor (G-CSF) receptor mediate G-CSF-induced differentiation of murine myeloid leukemic (M1) cells.
The Journal of biological chemistry 1996;271(43):26947-53.