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Louis Staudt
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41
Rosenwald, Andreas
22
Chan, Wing
21
Gascoyne, Randy
18
Jaffe, Elaine
17
Delabie, Jan
17
Campo, Elias
16
Davis, Eric
16
Shaffer, Arthur
16
Weisenburger, Dennis
16
Wright, George
15
Ott, German
11
Rimsza, Lisa
11
Wilson, Wyndham
10
Greiner, Timothy
9
Dent, AL
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All Publications
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2009: Taylor James G; Cheuk Adam T; Tsang Patricia S; Chung Joon-Yong; Song Young K; Desai Krupa; Yu Yanlin; Chen Qing-Rong; Shah Kushal; Youngblood Victoria; Fang Jun; Kim Su Young; Yeung Choh; Helman Lee J; Mendoza Arnulfo; Ngo Vu; Staudt Louis M; Wei Jun S; Khanna Chand; Catchpoole Daniel; Qualman Stephen J; Hewitt Stephen M; Merlino Glenn; Chanock Stephen J; Khan Javed
Identification of FGFR4-activating mutations in human rhabdomyosarcomas that promote metastasis in xenotransplanted models.
The Journal of clinical investigation 2009;119(11):3395-407.
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2009: Choi William W L; Weisenburger Dennis D; Greiner Timothy C; Piris Miguel A; Banham Alison H; Delabie Jan; Braziel Rita M; Geng Huimin; Iqbal Javeed; Lenz Georg; Vose Julie M; Hans Christine P; Fu Kai; Smith Lynette M; Li Min; Liu Zhongfeng; Gascoyne Randy D; Rosenwald Andreas; Ott German; Rimsza Lisa M; Campo Elias; Jaffe Elaine S; Jaye David L; Staudt Louis M; Chan Wing C
A new immunostain algorithm classifies diffuse large B-cell lymphoma into molecular subtypes with high accuracy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(17):5494-502.
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2009: Coffey Greg P; Rajapaksa Ranjani; Liu Raymond; Sharpe Orr; Kuo Chiung-Chi; Krauss Sharon Wald; Sagi Yael; Davis R Eric; Staudt Louis M; Sharman Jeff P; Robinson William H; Levy Shoshana
Engagement of CD81 induces ezrin tyrosine phosphorylation and its cellular redistribution with filamentous actin.
Journal of cell science 2009;122(Pt 17):3137-44.
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2009: Leich Ellen; Salaverria Itziar; Bea Silvia; Zettl Andreas; Wright George; Moreno Victor; Gascoyne Randy D; Chan Wing-Chung; Braziel Rita M; Rimsza Lisa M; Weisenburger Dennis D; Delabie Jan; Jaffe Elaine S; Lister Andrew; Fitzgibbon Jude; Staudt Louis M; Hartmann Elena M; Mueller-Hermelink Hans-Konrad; Campo Elias; Ott German; Rosenwald Andreas
Follicular lymphomas with and without translocation t(14;18) differ in gene expression profiles and genetic alterations.
Blood 2009;114(4):826-34.
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2009: Dunleavy Kieron; Pittaluga Stefania; Czuczman Myron S; Dave Sandeep S; Wright George; Grant Nicole; Shovlin Margaret; Jaffe Elaine S; Janik John E; Staudt Louis M; Wilson Wyndham H
Differential efficacy of bortezomib plus chemotherapy within molecular subtypes of diffuse large B-cell lymphoma.
Blood 2009;113(24):6069-76.
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2009: Shaffer Arthur L; Emre N C Tolga; Romesser Paul B; Staudt Louis M
IRF4: Immunity. Malignancy! Therapy?
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(9):2954-61.
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2009: Bidère Nicolas; Ngo Vu N; Lee Jeansun; Collins Cailin; Zheng Lixin; Wan Fengyi; Davis R Eric; Lenz Georg; Anderson D Eric; Arnoult Damien; Vazquez Aimé; Sakai Keiko; Zhang Jun; Meng Zhaojing; Veenstra Timothy D; Staudt Louis M; Lenardo Michael J
Casein kinase 1alpha governs antigen-receptor-induced NF-kappaB activation and human lymphoma cell survival.
Nature 2009;458(7234):92-6.
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2008: Lam Lloyd T; Davis R Eric; Ngo Vu N; Lenz Georg; Wright George; Xu Weihong; Zhao Hong; Yu Xin; Dang Lenny; Staudt Louis M
Compensatory IKKalpha activation of classical NF-kappaB signaling during IKKbeta inhibition identified by an RNA interference sensitization screen.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(52):20798-803.
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2008: Lenz Georg; Wright George W; Emre N C Tolga; Kohlhammer Holger; Dave Sandeep S; Davis R Eric; Carty Shannon; Lam Lloyd T; Shaffer A L; Xiao Wenming; Powell John; Rosenwald Andreas; Ott German; Muller-Hermelink Hans Konrad; Gascoyne Randy D; Connors Joseph M; Campo Elias; Jaffe Elaine S; Delabie Jan; Smeland Erlend B; Rimsza Lisa M; Fisher Richard I; Weisenburger Dennis D; Chan Wing C; Staudt Louis M
Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(36):13520-5.
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2008: Salaverria Itziar; Zettl Andreas; Beà Silvia; Hartmann Elena M; Dave Sandeep S; Wright George W; Boerma Evert-Jan; Kluin Philip M; Ott German; Chan Wing C; Weisenburger Dennis D; Lopez-Guillermo Armando; Gascoyne Randy D; Delabie Jan; Rimsza Lisa M; Braziel Rita M; Jaffe Elaine S; Staudt Louis M; Müller-Hermelink Hans Konrad; Campo Elias; Rosenwald Andreas;
Chromosomal alterations detected by comparative genomic hybridization in subgroups of gene expression-defined Burkitt's lymphoma.
Haematologica 2008;93(9):1327-34.
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2008: Shaffer Arthur L; Emre N C Tolga; Lamy Laurence; Ngo Vu N; Wright George; Xiao Wenming; Powell John; Dave Sandeep; Yu Xin; Zhao Hong; Zeng Yuxin; Chen Bangzheng; Epstein Joshua; Staudt Louis M
IRF4 addiction in multiple myeloma.
Nature 2008;454(7201):226-31.
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2008: Wilson Wyndham H; Dunleavy Kieron; Pittaluga Stefania; Hegde Upendra; Grant Nicole; Steinberg Seth M; Raffeld Mark; Gutierrez Martin; Chabner Bruce A; Staudt Louis; Jaffe Elaine S; Janik John E
Phase II study of dose-adjusted EPOCH and rituximab in untreated diffuse large B-cell lymphoma with analysis of germinal center and post-germinal center biomarkers.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(16):2717-24.
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2008: Lam Lloyd T; Wright George; Davis R Eric; Lenz Georg; Farinha Pedro; Dang Lenny; Chan John W; Rosenwald Andreas; Gascoyne Randy D; Staudt Louis M
Cooperative signaling through the signal transducer and activator of transcription 3 and nuclear factor-{kappa}B pathways in subtypes of diffuse large B-cell lymphoma.
Blood 2008;111(7):3701-13.
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2008: Lenz Georg; Davis R Eric; Ngo Vu N; Lam Lloyd; George Thaddeus C; Wright George W; Dave Sandeep S; Zhao Hong; Xu Weihong; Rosenwald Andreas; Ott German; Muller-Hermelink Hans Konrad; Gascoyne Randy D; Connors Joseph M; Rimsza Lisa M; Campo Elias; Jaffe Elaine S; Delabie Jan; Smeland Erlend B; Fisher Richard I; Chan Wing C; Staudt Louis M
Oncogenic CARD11 mutations in human diffuse large B cell lymphoma.
Science (New York, N.Y.) 2008;319(5870):1676-9.
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2008: Baskar Sivasubramanian; Kwong Ka Yin; Hofer Thomas; Levy Jessica M; Kennedy Michael G; Lee Elinor; Staudt Louis M; Wilson Wyndham H; Wiestner Adrian; Rader Christoph
Unique cell surface expression of receptor tyrosine kinase ROR1 in human B-cell chronic lymphocytic leukemia.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(2):396-404.
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2008: Xie Yuli; Deng ShiXian; Thomas Craig J; Liu Yidong; Zhang Ya-Qin; Rinderspacher Alison; Huang Wenwei; Gong Gangli; Wyler Michael; Cayanis Efithia; Aulner Nathalie; Többen Udo; Chung Caty; Pampou Sergey; Southall Noel; Vidovic Dusica; Schürer Stephan; Branden Lars; Davis R Eric; Staudt Louis M; Inglese James; Austin Christopher P; Landry Donald W; Smith Deborah H; Auld Douglas S
Identification of N-(quinolin-8-yl)benzenesulfonamides as agents capable of down-regulating NFkappaB activity within two separate high-throughput screens of NFkappaB activation.
Bioorganic & medicinal chemistry letters 2008;18(1):329-35.
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2007: Kimm Lindsey R; deLeeuw Ronald J; Savage Kerry J; Rosenwald Andreas; Campo Elias; Delabie Jan; Ott German; Muller-Hermelink Hans-Konrad; Jaffe Elaine S; Rimsza Lisa M; Weisenburger Dennis D; Chan Wing C; Staudt Louis M; Connors Joseph M; Gascoyne Randy D; Lam Wan L
Frequent occurrence of deletions in primary mediastinal B-cell lymphoma.
Genes, chromosomes & cancer 2007;46(12):1090-7.
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2007: Iqbal J; Greiner T C; Patel K; Dave B J; Smith L; Ji J; Wright G; Sanger W G; Pickering D L; Jain S; Horsman D E; Shen Y; Fu K; Weisenburger D D; Hans C P; Campo E; Gascoyne R D; Rosenwald A; Jaffe E S; Delabie J; Rimsza L; Ott G; Müller-Hermelink H K; Connors J M; Vose J M; McKeithan T; Staudt L M; Chan W C;
Distinctive patterns of BCL6 molecular alterations and their functional consequences in different subgroups of diffuse large B-cell lymphoma.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2007;21(11):2332-43.
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2007: Hystad Marit E; Myklebust June H; Bø Trond H; Sivertsen Einar A; Rian Edith; Forfang Lise; Munthe Else; Rosenwald Andreas; Chiorazzi Michael; Jonassen Inge; Staudt Louis M; Smeland Erlend B
Characterization of early stages of human B cell development by gene expression profiling.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(6):3662-71.
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2007: Annunziata Christina M; Davis R Eric; Demchenko Yulia; Bellamy William; Gabrea Ana; Zhan Fenghuang; Lenz Georg; Hanamura Ichiro; Wright George; Xiao Wenming; Dave Sandeep; Hurt Elaine M; Tan Bruce; Zhao Hong; Stephens Owen; Santra Madhumita; Williams David R; Dang Lenny; Barlogie Bart; Shaughnessy John D; Kuehl W Michael; Staudt Louis M
Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma.
Cancer cell 2007;12(2):115-30.
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2007: Dunleavy Kieron; Staudt Louis M; Wilson Wyndham H
The BCL-2 biomarker in the era of molecular diagnosis of diffuse large B-cell lymphoma.
Leukemia & lymphoma 2007;48(6):1061-3.
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2007: Wiestner Adrian; Tehrani Mahsa; Chiorazzi Michael; Wright George; Gibellini Federica; Nakayama Kazutaka; Liu Hui; Rosenwald Andreas; Muller-Hermelink H Konrad; Ott German; Chan Wing C; Greiner Timothy C; Weisenburger Dennis D; Vose Julie; Armitage James O; Gascoyne Randy D; Connors Joseph M; Campo Elias; Montserrat Emilio; Bosch Francesc; Smeland Erlend B; Kvaloy Stein; Holte Harald; Delabie Jan; Fisher Richard I; Grogan Thomas M; Miller Thomas P; Wilson Wyndham H; Jaffe Elaine S; Staudt Louis M
Point mutations and genomic deletions in CCND1 create stable truncated cyclin D1 mRNAs that are associated with increased proliferation rate and shorter survival.
Blood 2007;109(11):4599-606.
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2007: Kuo Tracy C; Shaffer Arthur L; Haddad Joseph; Choi Yong Sung; Staudt Louis M; Calame Kathryn
Repression of BCL-6 is required for the formation of human memory B cells in vitro.
The Journal of experimental medicine 2007;204(4):819-30.
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2007: Salaverria Itziar; Zettl Andreas; Beà Sílvia; Moreno Victor; Valls Joan; Hartmann Elena; Ott German; Wright George; Lopez-Guillermo Armando; Chan Wing C; Weisenburger Dennis D; Gascoyne Randy D; Grogan Thomas M; Delabie Jan; Jaffe Elaine S; Montserrat Emili; Muller-Hermelink Hans-Konrad; Staudt Louis M; Rosenwald Andreas; Campo Elias
Specific secondary genetic alterations in mantle cell lymphoma provide prognostic information independent of the gene expression-based proliferation signature.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(10):1216-22.
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2007: Lenz Georg; Nagel Inga; Siebert Reiner; Roschke Anna V; Sanger Warren; Wright George W; Dave Sandeep S; Tan Bruce; Zhao Hong; Rosenwald Andreas; Muller-Hermelink Hans Konrad; Gascoyne Randy D; Campo Elias; Jaffe Elaine S; Smeland Erlend B; Fisher Richard I; Kuehl W Michael; Chan Wing C; Staudt Louis M
Aberrant immunoglobulin class switch recombination and switch translocations in activated B cell-like diffuse large B cell lymphoma.
The Journal of experimental medicine 2007;204(3):633-43.
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2007: Davis R Eric; Zhang Ya-Qin; Southall Noel; Staudt Louis M; Austin Christopher P; Inglese James; Auld Douglas S
A cell-based assay for IkappaBalpha stabilization using a two-color dual luciferase-based sensor.
Assay and drug development technologies 2007;5(1):85-103.
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2007: Staudt Louis M
A closer look at follicular lymphoma.
The New England journal of medicine 2007;356(7):741-2.
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2007: Dunleavy Kieron; Davis R Eric; Landgren Ola; Staudt Louis M; Wilson Wyndham H
BCL-6 and rituximab in diffuse large B-cell lymphoma: where are we?
Blood 2007;109(2):843-4; discussion 844-5.
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2007: Mestre-Escorihuela Cinta; Rubio-Moscardo Fanny; Richter Jose A; Siebert Reiner; Climent Joan; Fresquet Vicente; Beltran Elena; Agirre Xabier; Marugan Isabel; Marín Miguel; Rosenwald Andreas; Sugimoto Kei-Ji; Wheat Luise M; Karran E Loraine; García Juan F; Sanchez Lydia; Prosper Felipe; Staudt Louis M; Pinkel Daniel; Dyer Martin J S; Martinez-Climent Jose A
Homozygous deletions localize novel tumor suppressor genes in B-cell lymphomas.
Blood 2007;109(1):271-80.
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2006: Roberts Robin A; Wright George; Rosenwald Andreas R; Jaramillo Marina A; Grogan Thomas M; Miller Thomas P; Frutiger Yvette; Chan Wing C; Gascoyne Randy D; Ott German; Muller-Hermelink H Konrad; Staudt Louis M; Rimsza Lisa M
Loss of major histocompatibility class II gene and protein expression in primary mediastinal large B-cell lymphoma is highly coordinated and related to poor patient survival.
Blood 2006;108(1):311-8.
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2006: Ngo Vu N; Davis R Eric; Lamy Laurence; Yu Xin; Zhao Hong; Lenz Georg; Lam Lloyd T; Dave Sandeep; Yang Liming; Powell John; Staudt Louis M
A loss-of-function RNA interference screen for molecular targets in cancer.
Nature 2006;441(7089):106-10.
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2006: Shaffer Arthur L; Wright George; Yang Liming; Powell John; Ngo Vu; Lamy Laurence; Lam Lloyd T; Davis R Eric; Staudt Louis M
A library of gene expression signatures to illuminate normal and pathological lymphoid biology.
Immunological reviews 2006;210():67-85.
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2006: Spence Susan L; Shaffer Arthur L; Staudt Louis M; Amde Sewit; Manney Sutana; Terry Cheryl; Weisz Keith; Nissley Peter
Transformation of late passage insulin-like growth factor-I receptor null mouse embryo fibroblasts by SV40 T antigen.
Cancer research 2006;66(8):4233-9.
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2006: Greiner Timothy C; Dasgupta Chiranjib; Ho Vincent V; Weisenburger Dennis D; Smith Lynette M; Lynch James C; Vose Julie M; Fu Kai; Armitage James O; Braziel Rita M; Campo Elias; Delabie Jan; Gascoyne Randy D; Jaffe Elaine S; Muller-Hermelink Hans K; Ott German; Rosenwald Andreas; Staudt Louis M; Im Michael Y; Karaman Mazen W; Pike Brian L; Chan Wing C; Hacia Joseph G
Mutation and genomic deletion status of ataxia telangiectasia mutated (ATM) and p53 confer specific gene expression profiles in mantle cell lymphoma.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(7):2352-7.
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2006: Iqbal Javeed; Neppalli Vishala T; Wright George; Dave Bhavana J; Horsman Douglas E; Rosenwald Andreas; Lynch James; Hans Christine P; Weisenburger Dennis D; Greiner Timothy C; Gascoyne Randy D; Campo Elias; Ott German; Müller-Hermelink H Konrad; Delabie Jan; Jaffe Elaine S; Grogan Thomas M; Connors Joseph M; Vose Julie M; Armitage James O; Staudt Louis M; Chan Wing C
BCL2 expression is a prognostic marker for the activated B-cell-like type of diffuse large B-cell lymphoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(6):961-8.
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2006: Rimsza Lisa M; Roberts Robin A; Campo Elias; Grogan Thomas M; Bea Silvia; Salaverria Itziar; Zettl Andreas; Rosenwald Andreas; Ott German; Muller-Hermelink H Konrad; Delabie Jan; Fisher Richard I; Unger Joseph M; Leblanc Michael; Staudt Louis M; Jaffe Elaine S; Gascoyne Randy D; Chan Wing C; Weisenburger Dennis D; Greiner Timothy; Braziel Rita M; Miller Thomas P
Loss of major histocompatibility class II expression in non-immune-privileged site diffuse large B-cell lymphoma is highly coordinated and not due to chromosomal deletions.
Blood 2006;107(3):1101-7.
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2005: Fu Kai; Weisenburger Dennis D; Greiner Timothy C; Dave Sandeep; Wright George; Rosenwald Andreas; Chiorazzi Michael; Iqbal Javeed; Gesk Stefan; Siebert Reiner; De Jong Daphne; Jaffe Elaine S; Wilson Wyndham H; Delabie Jan; Ott German; Dave Bhavana J; Sanger Warren G; Smith Lynette M; Rimsza Lisa; Braziel Rita M; Müller-Hermelink H Konrad; Campo Elias; Gascoyne Randy D; Staudt Louis M; Chan Wing C;
Cyclin D1-negative mantle cell lymphoma: a clinicopathologic study based on gene expression profiling.
Blood 2005;106(13):4315-21.
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2005: Rubio-Moscardo Fanny; Blesa David; Mestre Cinta; Siebert Reiner; Balasas Theo; Benito Adalberto; Rosenwald Andreas; Climent Joan; Martinez Jose I; Schilhabel Markus; Karran E Lorraine; Gesk Stefan; Esteller Manel; deLeeuw Ronald; Staudt Louis M; Fernandez-Luna Jose Luis; Pinkel Daniel; Dyer Martin J S; Martinez-Climent Jose A
Characterization of 8p21.3 chromosomal deletions in B-cell lymphoma: TRAIL-R1 and TRAIL-R2 as candidate dosage-dependent tumor suppressor genes.
Blood 2005;106(9):3214-22.
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2005: Park Sung Sup; Shaffer Arthur L; Kim Joong Su; duBois Wendy; Potter Michael; Staudt Louis M; Janz Siegfried
Insertion of Myc into Igh accelerates peritoneal plasmacytomas in mice.
Cancer research 2005;65(17):7644-52.
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2005: Mestre C; Rubio-Moscardo F; Rosenwald A; Climent J; Dyer M J S; Staudt L; Pinkel D; Siebert R; Martinez-Climent J A
Homozygous deletion of SOCS1 in primary mediastinal B-cell lymphoma detected by CGH to BAC microarrays.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2005;19(6):1082-4.
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2005: Lam Lloyd T; Davis R Eric; Pierce Jackie; Hepperle Michael; Xu Yajun; Hottelet Maria; Nong Yuhua; Wen Danyi; Adams Julian; Dang Lenny; Staudt Louis M
Small molecule inhibitors of IkappaB kinase are selectively toxic for subgroups of diffuse large B-cell lymphoma defined by gene expression profiling.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(1):28-40.
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2005: Han Seong Su; Shaffer Arthur L; Peng Liangping; Chung Seung Tae; Lim Jae Hwan; Maeng Sungho; Kim Joong Su; McNeil Nicole; Ried Thomas; Staudt Louis M; Janz Siegfried
Molecular and cytological features of the mouse B-cell lymphoma line iMycEmu-1.
Molecular cancer 2005;4():40.
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2005: Staudt Louis M; Dave Sandeep
The biology of human lymphoid malignancies revealed by gene expression profiling.
Advances in immunology 2005;87():163-208.
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2004: Shen Yulei; Iqbal Javeed; Xiao Li; Lynch Ryan C; Rosenwald Andreas; Staudt Louis M; Sherman Simon; Dybkaer Karen; Zhou Guimei; Eudy James D; Delabie Jan; McKeithan Timothy W; Chan Wing C
Distinct gene expression profiles in different B-cell compartments in human peripheral lymphoid organs.
BMC immunology 2004;5():20.
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2004: de Leeuw Ronald J; Davies Jonathan J; Rosenwald Andreas; Bebb Gwyn; Gascoyne Randy D; Dyer Martin J S; Staudt Louis M; Martinez-Climent Jose A; Lam Wan L
Comprehensive whole genome array CGH profiling of mantle cell lymphoma model genomes.
Human molecular genetics 2004;13(17):1827-37.
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2004: Rosenwald Andreas; Chuang Eric Y; Davis R Eric; Wiestner Adrian; Alizadeh Ash A; Arthur Diane C; Mitchell James B; Marti Gerald E; Fowler Daniel H; Wilson Wyndham H; Staudt Louis M
Fludarabine treatment of patients with chronic lymphocytic leukemia induces a p53-dependent gene expression response.
Blood 2004;104(5):1428-34.
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2004: Shaffer A L; Shapiro-Shelef Miriam; Iwakoshi Neal N; Lee Ann-Hwee; Qian Shu-Bing; Zhao Hong; Yu Xin; Yang Liming; Tan Bruce K; Rosenwald Andreas; Hurt Elaine M; Petroulakis Emmanuel; Sonenberg Nahum; Yewdell Jonathan W; Calame Kathryn; Glimcher Laurie H; Staudt Louis M
XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation.
Immunity 2004;21(1):81-93.
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2004: Tunyaplin Chainarong; Shaffer A L; Angelin-Duclos Cristina D; Yu Xin; Staudt Louis M; Calame Kathryn L
Direct repression of prdm1 by Bcl-6 inhibits plasmacytic differentiation.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(2):1158-65.
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2004: Iqbal Javeed; Sanger Warren G; Horsman Douglas E; Rosenwald Andreas; Pickering Diane L; Dave Bhavana; Dave Sandeep; Xiao Li; Cao Kajia; Zhu Quiming; Sherman Simon; Hans Christine P; Weisenburger Dennis D; Greiner Timothy C; Gascoyne Randy D; Ott German; Müller-Hermelink H Konrad; Delabie Jan; Braziel Rita M; Jaffe Elaine S; Campo Elias; Lynch James C; Connors Joseph M; Vose Julie M; Armitage James O; Grogan Thomas M; Staudt Louis M; Chan Wing C
BCL2 translocation defines a unique tumor subset within the germinal center B-cell-like diffuse large B-cell lymphoma.
The American journal of pathology 2004;165(1):159-66.
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2004: Rimsza Lisa M; Roberts Robin A; Miller Thomas P; Unger Joseph M; LeBlanc Michael; Braziel Rita M; Weisenberger Dennis D; Chan Wing C; Muller-Hermelink H Konrad; Jaffe Elaine S; Gascoyne Randy D; Campo Elias; Fuchs Deborah A; Spier Catherine M; Fisher Richard I; Delabie Jan; Rosenwald Andreas; Staudt Louis M; Grogan Thomas M
Loss of MHC class II gene and protein expression in diffuse large B-cell lymphoma is related to decreased tumor immunosurveillance and poor patient survival regardless of other prognostic factors: a follow-up study from the Leukemia and Lymphoma Molecular Profiling Project.
Blood 2004;103(11):4251-8.
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2004: Cahir-McFarland Ellen D; Carter Kara; Rosenwald Andreas; Giltnane Jena M; Henrickson Sarah E; Staudt Louis M; Kieff Elliott
Role of NF-kappa B in cell survival and transcription of latent membrane protein 1-expressing or Epstein-Barr virus latency III-infected cells.
Journal of virology 2004;78(8):4108-19.
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2004: Hurt Elaine M; Wiestner Adrian; Rosenwald Andreas; Shaffer A L; Campo Elias; Grogan Tom; Bergsagel P Leif; Kuehl W Michael; Staudt Louis M
Overexpression of c-maf is a frequent oncogenic event in multiple myeloma that promotes proliferation and pathological interactions with bone marrow stroma.
Cancer cell 2004;5(2):191-9.
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2004: Orchard Jenny A; Ibbotson Rachel E; Davis Zadie; Wiestner Adrian; Rosenwald Andreas; Thomas Peter W; Hamblin Terry J; Staudt Louis M; Oscier David G
ZAP-70 expression and prognosis in chronic lymphocytic leukaemia.
Lancet 2004;363(9403):105-11.
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2004: Hans Christine P; Weisenburger Dennis D; Greiner Timothy C; Gascoyne Randy D; Delabie Jan; Ott German; Müller-Hermelink H Konrad; Campo Elias; Braziel Rita M; Jaffe Elaine S; Pan Zenggang; Farinha Pedro; Smith Lynette M; Falini Brunangelo; Banham Alison H; Rosenwald Andreas; Staudt Louis M; Connors Joseph M; Armitage James O; Chan Wing C
Confirmation of the molecular classification of diffuse large B-cell lymphoma by immunohistochemistry using a tissue microarray.
Blood 2004;103(1):275-82.
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2003: McConnell Melanie J; Chevallier Nathalie; Berkofsky-Fessler Windy; Giltnane Jena M; Malani Rupal B; Staudt Louis M; Licht Jonathan D
Growth suppression by acute promyelocytic leukemia-associated protein PLZF is mediated by repression of c-myc expression.
Molecular and cellular biology 2003;23(24):9375-88.
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2003: Wiestner Adrian; Staudt Louis M
Towards molecular diagnosis and targeted therapy of lymphoid malignancies.
Seminars in hematology 2003;40(4):296-307.
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2003: Wright George; Tan Bruce; Rosenwald Andreas; Hurt Elaine H; Wiestner Adrian; Staudt Louis M
A gene expression-based method to diagnose clinically distinct subgroups of diffuse large B cell lymphoma.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(17):9991-6.
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2003: Pan Zenggang; Shen Yulei; Du Cheng; Zhou Guimei; Rosenwald Andreas; Staudt Louis M; Greiner Timothy C; McKeithan Timothy W; Chan Wing C
Two newly characterized germinal center B-cell-associated genes, GCET1 and GCET2, have differential expression in normal and neoplastic B cells.
The American journal of pathology 2003;163(1):135-44.
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2003: Wiestner Adrian; Rosenwald Andreas; Barry Todd S; Wright George; Davis R Eric; Henrickson Sarah E; Zhao Hong; Ibbotson Rachel E; Orchard Jenny A; Davis Zadie; Stetler-Stevenson Maryalice; Raffeld Mark; Arthur Diane C; Marti Gerald E; Wilson Wyndham H; Hamblin Terry J; Oscier David G; Staudt Louis M
ZAP-70 expression identifies a chronic lymphocytic leukemia subtype with unmutated immunoglobulin genes, inferior clinical outcome, and distinct gene expression profile.
Blood 2003;101(12):4944-51.
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2003: Sanchez-Izquierdo Dolors; Buchonnet Gerard; Siebert Reiner; Gascoyne Randy D; Climent Joan; Karran Loraine; Marin Miguel; Blesa David; Horsman Douglas; Rosenwald Andreas; Staudt Louis M; Albertson Donna G; Du Ming-Qing; Ye Hongtao; Marynen Peter; Garcia-Conde Javier; Pinkel Daniel; Dyer Martin J S; Martinez-Climent Jose Angel
MALT1 is deregulated by both chromosomal translocation and amplification in B-cell non-Hodgkin lymphoma.
Blood 2003;101(11):4539-46.
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2003: Staudt Louis M
Molecular diagnosis of the hematologic cancers.
The New England journal of medicine 2003;348(18):1777-85.
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2003: Kovanen Panu E; Rosenwald Andreas; Fu Jacqueline; Hurt Elaine M; Lam Lloyd T; Giltnane Jena M; Wright George; Staudt Louis M; Leonard Warren J
Analysis of gamma c-family cytokine target genes. Identification of dual-specificity phosphatase 5 (DUSP5) as a regulator of mitogen-activated protein kinase activity in interleukin-2 signaling.
The Journal of biological chemistry 2003;278(7):5205-13.
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2003: Rosenwald Andreas; Staudt Louis M
Gene expression profiling of diffuse large B-cell lymphoma.
Leukemia & lymphoma 2003;44 Suppl 3():S41-7.
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2002: Shaffer A L; Rosenwald Andreas; Staudt Louis M
Lymphoid malignancies: the dark side of B-cell differentiation.
Nature reviews. Immunology 2002;2(12):920-32.
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2002: Staudt Louis M; Wilson Wyndham H
Focus on lymphomas.
Cancer cell 2002;2(5):363-6.
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2002: Shaffer A L; Lin Kuo I; Kuo Tracy C; Yu Xin; Hurt Elaine M; Rosenwald Andreas; Giltnane Jena M; Yang Liming; Zhao Hong; Calame Kathryn; Staudt Louis M
Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program.
Immunity 2002;17(1):51-62.
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2002: Davis R Eric; Staudt Louis M
Molecular diagnosis of lymphoid malignancies by gene expression profiling.
Current opinion in hematology 2002;9(4):333-8.
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2002: Rosenwald Andreas; Staudt Louis M
Clinical translation of gene expression profiling in lymphomas and leukemias.
Seminars in oncology 2002;29(3):258-63.
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2002: Huang James Z; Sanger Warren G; Greiner Timothy C; Staudt Louis M; Weisenburger Dennis D; Pickering Diane L; Lynch James C; Armitage James O; Warnke Roger A; Alizadeh Ash A; Lossos Izidore S; Levy Ronald; Chan Wing C
The t(14;18) defines a unique subset of diffuse large B-cell lymphoma with a germinal center B-cell gene expression profile.
Blood 2002;99(7):2285-90.
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2002: Staudt Louis M
It's ALL in the diagnosis.
Cancer cell 2002;1(2):109-10.
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2002: Boldrick Jennifer C; Alizadeh Ash A; Diehn Maximilian; Dudoit Sandrine; Liu Chih Long; Belcher Christopher E; Botstein David; Staudt Louis M; Brown Patrick O; Relman David A
Stereotyped and specific gene expression programs in human innate immune responses to bacteria.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(2):972-7.
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2002: Staudt Louis M
Gene expression profiling of lymphoid malignancies.
Annual review of medicine 2002;53():303-18.
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2001: Davis R E; Brown K D; Siebenlist U; Staudt L M
Constitutive nuclear factor kappaB activity is required for survival of activated B cell-like diffuse large B cell lymphoma cells.
The Journal of experimental medicine 2001;194(12):1861-74.
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2001: Rosenwald A; Alizadeh A A; Widhopf G; Simon R; Davis R E; Yu X; Yang L; Pickeral O K; Rassenti L Z; Powell J; Botstein D; Byrd J C; Grever M R; Cheson B D; Chiorazzi N; Wilson W H; Kipps T J; Brown P O; Staudt L M
Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia.
The Journal of experimental medicine 2001;194(11):1639-47.
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2001: Shaffer A L; Rosenwald A; Hurt E M; Giltnane J M; Lam L T; Pickeral O K; Staudt L M
Signatures of the immune response.
Immunity 2001;15(3):375-85.
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2001: Ma C; Staudt L M
Molecular definition of the germinal centre stage of B-cell differentiation.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2001;356(1405):83-9.
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2001: Lam L T; Pickeral O K; Peng A C; Rosenwald A; Hurt E M; Giltnane J M; Averett L M; Zhao H; Davis R E; Sathyamoorthy M; Wahl L M; Harris E D; Mikovits J A; Monks A P; Hollingshead M G; Sausville E A; Staudt L M
Genomic-scale measurement of mRNA turnover and the mechanisms of action of the anti-cancer drug flavopiridol.
Genome biology 2001;2(10):RESEARCH0041.
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2000: Shaffer A L; Yu X; He Y; Boldrick J; Chan E P; Staudt L M
BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control.
Immunity 2000;13(2):199-212.
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2000: Alizadeh A A; Staudt L M
Genomic-scale gene expression profiling of normal and malignant immune cells.
Current opinion in immunology 2000;12(2):219-25.
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2000: Staudt L M
The molecular and cellular origins of Hodgkin's disease.
The Journal of experimental medicine 2000;191(2):207-12.
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2000: Hastie T; Tibshirani R; Eisen M B; Alizadeh A; Levy R; Staudt L; Chan W C; Botstein D; Brown P
'Gene shaving' as a method for identifying distinct sets of genes with similar expression patterns.
Genome biology 2000;1(2):RESEARCH0003.
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1999: Dent A L; Doherty T M; Paul W E; Sher A; Staudt L M
BCL-6-deficient mice reveal an IL-4-independent, STAT6-dependent pathway that controls susceptibility to infection by Leishmania major.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(4):2098-103.
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1999: Iyer V R; Eisen M B; Ross D T; Schuler G; Moore T; Lee J C; Trent J M; Staudt L M; Hudson J; Boguski M S; Lashkari D; Shalon D; Botstein D; Brown P O
The transcriptional program in the response of human fibroblasts to serum.
Science (New York, N.Y.) 1999;283(5398):83-7.
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1999: Alizadeh A; Eisen M; Davis R E; Ma C; Sabet H; Tran T; Powell J I; Yang L; Marti G E; Moore D T; Hudson J R; Chan W C; Greiner T; Weisenburger D; Armitage J O; Lossos I; Levy R; Botstein D; Brown P O; Staudt L M
The lymphochip: a specialized cDNA microarray for the genomic-scale analysis of gene expression in normal and malignant lymphocytes.
Cold Spring Harbor symposia on quantitative biology 1999;64():71-8.
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1999: Staudt L M; Dent A L; Shaffer A L; Yu X
Regulation of lymphocyte cell fate decisions and lymphomagenesis by BCL-6.
International reviews of immunology 1999;18(4):381-403.
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1998: Alizadeh A; Eisen M; Botstein D; Brown P O; Staudt L M
Probing lymphocyte biology by genomic-scale gene expression analysis.
Journal of clinical immunology 1998;18(6):373-9.
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1998: Dent A L; Hu-Li J; Paul W E; Staudt L M
T helper type 2 inflammatory disease in the absence of interleukin 4 and transcription factor STAT6.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(23):13823-8.
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1997: Dent A L; Shaffer A L; Yu X; Allman D; Staudt L M
Control of inflammation, cytokine expression, and germinal center formation by BCL-6.
Science (New York, N.Y.) 1997;276(5312):589-92.
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1996: Thornton A M; Ogryzko V V; Dent A; Sharf R; Levi B Z; Kanno Y; Staudt L M; Howard B H; Ozato K
A dominant negative mutant of an IFN regulatory factor family protein inhibits both type I and type II IFN-stimulated gene expression and antiproliferative activity of IFNs.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(11):5145-54.
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1996: Behrens T W; Kearns G M; Rivard J J; Bernstein H D; Yewdell J W; Staudt L M
Carboxyl-terminal targeting and novel post-translational processing of JAW1, a lymphoid protein of the endoplasmic reticulum.
The Journal of biological chemistry 1996;271(38):23528-34.
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1996: Dent A L; Yewdell J; Puvion-Dutilleul F; Koken M H; de The H; Staudt L M
LYSP100-associated nuclear domains (LANDs): description of a new class of subnuclear structures and their relationship to PML nuclear bodies.
Blood 1996;88(4):1423-6.
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1996: Liao X; Gilbert D J; Dent A; Staudt L M; Jenkins N A; Copeland N G
Mapping of the mouse Bcl6 gene to chromosome 16.
Mammalian genome : official journal of the International Mammalian Genome Society 1996;7(8):621-2.
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1996: Vigano M A; Staudt L M
Transcriptional activation by Oct-3: evidence for a specific role of the POU-specific domain in mediating functional interaction with Oct-1.
Nucleic acids research 1996;24(11):2112-8.
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1996: Liao X; Ma C; Trask B; Massa H; Gilbert D J; Staudt L M; Jenkins N A; Copeland N G
LAF4 maps to mouse chromosome 1 and human chromosome 2q11.2-q12.
Mammalian genome : official journal of the International Mammalian Genome Society 1996;7(6):467-8.
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1996: Allman D; Jain A; Dent A; Maile R R; Selvaggi T; Kehry M R; Staudt L M
BCL-6 expression during B-cell activation.
Blood 1996;87(12):5257-68.
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1996: Seyfert V L; Allman D; He Y; Staudt L M
Transcriptional repression by the proto-oncogene BCL-6.
Oncogene 1996;12(11):2331-42.
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1996: Ma C; Staudt L M
LAF-4 encodes a lymphoid nuclear protein with transactivation potential that is homologous to AF-4, the gene fused to MLL in t(4;11) leukemias.
Blood 1996;87(2):734-45.
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1995: Stewart D M; Notarangelo L D; Kurman C C; Staudt L M; Nelson D L
Molecular genetic analysis of X-linked hypogammaglobulinemia and isolated growth hormone deficiency.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(5):2770-4.
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1995: Staudt L M; Dent A; Ma C; Allman D; Powell J; Maile R; Scherle P; Behrens T
Rapid identification of novel human lymphoid-restricted genes by automated DNA sequencing of subtracted cDNA libraries.
Current topics in microbiology and immunology 1995;194():155-61.
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1994: Behrens T W; Jagadeesh J; Scherle P; Kearns G; Yewdell J; Staudt L M
Jaw1, A lymphoid-restricted membrane protein localized to the endoplasmic reticulum.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(2):682-90.
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1993: Scherle P; Behrens T; Staudt L M
Ly-GDI, a GDP-dissociation inhibitor of the RhoA GTP-binding protein, is expressed preferentially in lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(16):7568-72.
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1992: Rosner M H; Vigano M A; Rigby P W; Arnheiter H; Staudt L M
Oct-3 and mammalian development: correction of discussion.
Science (New York, N.Y.) 1992;257(5067):147.
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1992: Kang S M; Tsang W; Doll S; Scherle P; Ko H S; Tran A C; Lenardo M J; Staudt L M
Induction of the POU domain transcription factor Oct-2 during T-cell activation by cognate antigen.
Molecular and cellular biology 1992;12(7):3149-54.
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1992: Rosner M; De Santo R J; Arnheiter H; Staudt L M
Retraction: Oct-3 is a maternal factor required for the first mouse embryonic division.
Cell 1992;69(5):724.
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1991: Rosner M H; Vigano M A; Rigby P W; Arnheiter H; Staudt L M
Oct-3 and the beginning of mammalian development.
Science (New York, N.Y.) 1991;253(5016):144-5.
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1991: Siracusa L D; Rosner M H; Vigano M A; Gilbert D J; Staudt L M; Copeland N G; Jenkins N A
Chromosomal location of the octamer transcription factors, Otf-1, Otf-2, and Otf-3, defines multiple Otf-3-related sequences dispersed in the mouse genome.
Genomics 1991;10(2):313-26.
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1991: Rosner M H; De Santo R J; Arnheiter H; Staudt L M
Oct-3 is a maternal factor required for the first mouse embryonic division.
Cell 1991;64(6):1103-10.
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1990: Rosner M H; Vigano M A; Ozato K; Timmons P M; Poirier F; Rigby P W; Staudt L M
A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo.
Nature 1990;345(6277):686-92.
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1989: Takimoto M; Quinn J P; Farina A R; Staudt L M; Levens D
fos/jun and octamer-binding protein interact with a common site in a negative element of the human c-myc gene.
The Journal of biological chemistry 1989;264(15):8992-9.
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1988: Ko H S; Fast P; McBride W; Staudt L M
A human protein specific for the immunoglobulin octamer DNA motif contains a functional homeobox domain.
Cell 1988;55(1):135-44.
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