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Philipp Stawowy

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Jan Kaufmann; Martin Meixner; Heike Meyborg; Aline Müller; Eckart Fleck; Kristof Graf; Tobias Hauptmann; Kai Kappert; Daniel Urban; Ernst Wellnhofer; Philipp Stawowy
Soluble P-selectin level correlates with acetylsalicylic acid but not with clopidogrel response in patients with stable coronary artery disease after a percutaneous coronary intervention.
Daniel Urban; Eckart Fleck; Sanchita Ghosh; Kai Kappert; Jan Kaufmann; Ulrich Kintscher; Janina Lorenz; Heike Meyborg; Philipp Stawowy
Proprotein convertase furin enhances survival and migration of vascular smooth muscle cells via processing of pro-nerve growth factor.
Sarah M Bernhard; Petra Goldin-Lang; Sebastian Kirsch; Sabrina Klare; Heike Meyborg; Jennifer Schmitz; Eva Schrezenmeier; Kerstin Seidel; Philipp Stawowy; Thomas Unger; Daniela Zaade; Frank S Zollmann; Heiko Funke-Kaiser
The (pro)renin receptor ((P)RR) can act as a repressor of Wnt signalling.

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All Publications

2013: Jan Kaufmann; Martin Meixner; Heike Meyborg; Aline Müller; Eckart Fleck; Kristof Graf; Tobias Hauptmann; Kai Kappert; Daniel Urban; Ernst Wellnhofer; Philipp Stawowy
Soluble P-selectin level correlates with acetylsalicylic acid but not with clopidogrel response in patients with stable coronary artery disease after a percutaneous coronary intervention.
Coronary artery disease 2013;24(4):312-20.
2013: Daniel Urban; Eckart Fleck; Sanchita Ghosh; Kai Kappert; Jan Kaufmann; Ulrich Kintscher; Janina Lorenz; Heike Meyborg; Philipp Stawowy
Proprotein convertase furin enhances survival and migration of vascular smooth muscle cells via processing of pro-nerve growth factor.
Journal of biochemistry 2013;153(2):197-207.
2012: Sarah M Bernhard; Petra Goldin-Lang; Sebastian Kirsch; Sabrina Klare; Heike Meyborg; Jennifer Schmitz; Eva Schrezenmeier; Kerstin Seidel; Philipp Stawowy; Thomas Unger; Daniela Zaade; Frank S Zollmann; Heiko Funke-Kaiser
The (pro)renin receptor ((P)RR) can act as a repressor of Wnt signalling.
Biochemical pharmacology 2012;84(12):1643-50.
2012: Mandy Bloch; Antonio Brunetti; Anna Foryst-Ludwig; Alfredo Fusco; Lena Herbst; Kai Kappert; Francesco Paonessa; André Prock; Daniel Sedding; Joachim Spranger; Philipp Stawowy; Thomas Unger; Henning Witt; Ilse Nirmala Bähr; Verena Benz; Ulrich Kintscher
High-mobility group A1 protein: a new coregulator of peroxisome proliferator-activated receptor-γ-mediated transrepression in the vasculature.
Circulation research 2012;110(3):394-405.
2012: André Duelsner; Nora Gatzke; Johanna Glaser; Philipp Hillmeister; Eun-Ji Lee; Kerstin Lehmann; Meijing Li; Heike Meyborg; Stephanie Nagorka; Philipp Stawowy; Daniel Urban; Anja Bondke Persson; Andreas Busjahn; Ivo R Buschmann
Granulocyte colony-stimulating factor improves cerebrovascular reserve capacity by enhancing collateral growth in the circle of Willis.
Cerebrovascular diseases (Basel, Switzerland) 2012;33(5):419-29.
2011: Jan Fritzsche; Philipp Stawowy
Time for endothelial cell proprotein convertase PC5/6 in cardiovascular medicine?
Journal of molecular medicine (Berlin, Germany) 2011;89(11):1061-3.
2011: Philipp Hillmeister; Imo E Hoefer; Carmen Infante-Duarte; Georg Jung; Ferdinand le Noble; Meijing Li; Stephanie Nagorka; Ines Schadock; Yu Shi; Philipp Stawowy; Kerstin Troidl; Daniel Urban; Haitao Wang; André Dülsner; Marco Frentsch; Nora Gatzke; Isabell Hamann; Michael Bader; Ivo R Buschmann
Arteriogenesis is modulated by bradykinin receptor signaling.
Circulation research 2011;109(5):524-33.
2011: Anna Foryst-Ludwig; Dennis Gürgen; Verena Benz; Christian Böhm; Duska Dragun; Michael C Kreissl; Knut Mai; Vera Regitz-Zagrosek; Carola Schubert; Christiane Sprang; Joachim Spranger; Philipp Stawowy; Beata Thalke; Thomas Unger; Ulrich Kintscher
Sex differences in physiological cardiac hypertrophy are associated with exercise-mediated changes in energy substrate availability.
American journal of physiology. Heart and circulatory physiology 2011;301(1):H115-22.
2011: Daniel Urban; Usan Thanabalasingam; Dietger Stibenz; Jan Kaufmann; Heike Meyborg; Eckart Fleck; Michael Gräfe; Philipp Stawowy
CD40/CD40L interaction induces E-selectin dependent leukocyte adhesion to human endothelial cells and inhibits endothelial cell migration.
Biochemical and biophysical research communications 2011;404(1):448-52.
2010: Vesna Furundzija; Jan Fritzsche; Jan Kaufmann; Heike Meyborg; Eckart Fleck; Kai Kappert; Philipp Stawowy
IGF-1 increases macrophage motility via PKC/p38-dependent alphavbeta3-integrin inside-out signaling.
Biochemical and biophysical research communications 2010;394(3):786-91.
2010: Kai Kappert; Vesna Furundzija; Jan Fritzsche; Christian Margeta; Janine Krüger; Heike Meyborg; Eckart Fleck; Philipp Stawowy
Integrin cleavage regulates bidirectional signalling in vascular smooth muscle cells.
Thrombosis and haemostasis 2010;103(3):556-63.
2009: Thore Dietrich; Thomas Hucko; Riad Bourayou; Cosima Jahnke; Ingo Paetsch; Kirstin Atrott; Philipp Stawowy; Michael Gräfe; Christoph Klein; Bernhard Schnackenburg; Eckart Fleck; Kristof Graf
High resolution magnetic resonance imaging in atherosclerotic mice treated with ezetimibe.
The international journal of cardiovascular imaging 2009;25(8):827-36.
2009: Kai Kappert; Oleg Tsuprykov; Jan Kaufmann; Jan Fritzsche; Ingo Ott; Matthias Goebel; Ilse Nirmala Bähr; Paul-Laszlo Hässle; Ronald Gust; Eckart Fleck; Thomas Unger; Philipp Stawowy; Ulrich Kintscher
Chronic treatment with losartan results in sufficient serum levels of the metabolite EXP3179 for PPARgamma activation.
Hypertension 2009;54(4):738-43.
2009: Kai Kappert; Heike Meyborg; Bernadette Baumann; Vesna Furundzija; Jan Kaufmann; Kristof Graf; Dietger Stibenz; Eckart Fleck; Philipp Stawowy
Integrin cleavage facilitates cell surface-associated proteolysis required for vascular smooth muscle cell invasion.
The international journal of biochemistry & cell biology 2009;41(7):1511-7.
2009: Patrick Micke; Daniel Hackbusch; Sibel Mercan; Philipp Stawowy; Oleg Tsuprykov; Thomas Unger; Arne Ostman; Kai Kappert
Regulation of tyrosine phosphatases in the adventitia during vascular remodelling.
Biochemical and biophysical research communications 2009;382(4):678-84.
2009: Patrick Asbach; Ingo Paetsch; Philipp Stawowy; Bernhard Sander; Eckart Fleck
Statin-associated focal myositis.
International journal of cardiology 2009;133(1):e33-4.
2008: Philipp Stawowy; Cosima Jahnke; Engin Osmanoglou; Roland Hetzer; Eckart Fleck; Ingo Paetsch
Acute isolated viral pericarditis with rapid progression to constrictive pericardial disease.
Circulation. Cardiovascular imaging 2008;1(2):173-4.
2008: Kristof Graf; Thomas Hucko; Philipp Stawowy
Cardiac benefits of mineralocorticoid receptor inhibition in renal failure.
Hypertension 2008;52(2):209-10.
2008: Mattias Roser; Ashraf Hamdan; Takeshi Komoda; Charalampos Kriatselis; Philipp Stawowy; Rudolf Meyer; Roland Hetzer; Christoph Knosalla; Ingo Paetsch
Images in cardiovascular medicine. Left ventricular cardiac hemangioma presenting with atypical chest pain.
Circulation 2008;117(22):2958-60.
2008: Kristof Graf; Thore Dietrich; Michael Tachezy; Frank-Detlef Scholle; Kai Licha; Philipp Stawowy; Michael Grafe; Peter Hauff; Eckart Fleck
Monitoring therapeutical intervention with ezetimibe using targeted near-infrared fluorescence imaging in experimental atherosclerosis.
Molecular imaging 2008;7(2):68-76.
2008: Mattias Roser; Johannes Möller; Takeshi Komoda; Christoph Knosalla; Philipp Stawowy
Alkaptonuric aortic stenosis.
European heart journal 2008;29(4):444.
2008: Kai Kappert; Heike Meyborg; Markus Clemenz; Kristof Graf; Eckart Fleck; Ulrich Kintscher; Philipp Stawowy
Insulin facilitates monocyte migration: a possible link to tissue inflammation in insulin-resistance.
Biochemical and biophysical research communications 2008;365(3):503-8.
2007: Thore Dietrich; Christin Perlitz; Kai Licha; Philipp Stawowy; Kirstin Atrott; Michael Tachezy; Heike Meyborg; Carolin Stocker; Michael Gräfe; Eckart Fleck; Michael Schirner; Kristof Graf
ED-B fibronectin (ED-B) can be targeted using a novel single chain antibody conjugate and is associated with macrophage accumulation in atherosclerotic lesions.
Basic research in cardiology 2007;102(4):298-307.
2007: Arne Fischoeder; Heike Meyborg; Dietger Stibenz; Eckart Fleck; Kristof Graf; Philipp Stawowy
Insulin augments matrix metalloproteinase-9 expression in monocytes.
Cardiovascular research 2007;73(4):841-8.
2005: Philipp Stawowy; Eckart Fleck
Proprotein convertases furin and PC5: targeting atherosclerosis and restenosis at multiple levels.
Journal of molecular medicine (Berlin, Germany) 2005;83(11):865-75.
2005: Philipp Stawowy; Christian Margeta; Florian Blaschke; Carsten Lindschau; Chantel Spencer-Hänsch; Michael Leitges; Giuseppe Biagini; Eckart Fleck; Kristof Graf
Protein kinase C epsilon mediates angiotensin II-induced activation of beta1-integrins in cardiac fibroblasts.
Cardiovascular research 2005;67(1):50-9.
2005: Philipp Stawowy; Heike Meyborg; Dietger Stibenz; Núbia Borges Pereira Stawowy; Mattias Roser; Usan Thanabalasingam; John P Veinot; Michel Chrétien; Nabil G Seidah; Eckart Fleck; Kristof Graf
Furin-like proprotein convertases are central regulators of the membrane type matrix metalloproteinase-pro-matrix metalloproteinase-2 proteolytic cascade in atherosclerosis.
Circulation 2005;111(21):2820-7.
2005: Philipp Stawowy; Heike Kallisch; Núbia Borges Pereira Stawowy; Dietger Stibenz; John P Veinot; Michael Gräfe; Nabil G Seidah; Michel Chrétien; Eckart Fleck; Kristof Graf
Immunohistochemical localization of subtilisin/kexin-like proprotein convertases in human atherosclerosis.
Virchows Archiv : an international journal of pathology 2005;446(4):351-9.
2004: Kristof Graf; Philipp Stawowy
Osteopontin: a protective mediator of cardiac fibrosis?
Hypertension 2004;44(6):809-10.
2004: Philipp Stawowy; Heike Kallisch; Adam Kilimnik; Christian Margeta; Nabil G Seidah; Michel Chrétien; Eckart Fleck; Kristof Graf
Proprotein convertases regulate insulin-like growth factor 1-induced membrane-type 1 matrix metalloproteinase in VSMCs via endoproteolytic activation of the insulin-like growth factor-1 receptor.
Biochemical and biophysical research communications 2004;321(3):531-8.
2004: Philipp Stawowy; Christian Margeta; Heike Kallisch; Nabil G Seidah; Michel Chrétien; Eckart Fleck; Kristof Graf
Regulation of matrix metalloproteinase MT1-MMP/MMP-2 in cardiac fibroblasts by TGF-beta1 involves furin-convertase.
Cardiovascular research 2004;63(1):87-97.
2004: M Neuss; Mattias Roser; Sebastian Kelle; F Girke; G Winbeck; Philipp Stawowy; Eckart Fleck
Calculation of individual cardiovascular risk in a primary prevention setting shows a high number of patients with a high risk score.
Zeitschrift für Kardiologie 2004;93(5):413-5.
2004: Philipp Stawowy; Heike Kallisch; John P Veinot; Adam Kilimnik; Wendy Prichett; Stephan Goetze; Nabil G Seidah; Michel Chrétien; Eckart Fleck; Kristof Graf
Endoproteolytic activation of alpha(v) integrin by proprotein convertase PC5 is required for vascular smooth muscle cell adhesion to vitronectin and integrin-dependent signaling.
Circulation 2004;109(6):770-6.
2003: Philipp Stawowy; Stephan Goetze; Christian Margeta; Eckart Fleck; Kristof Graf
LPS regulate ERK1/2-dependent signaling in cardiac fibroblasts via PKC-mediated MKP-1 induction.
Biochemical and biophysical research communications 2003;303(1):74-80.
2003: Philipp Stawowy; Kristof Graf; Stephan Goetze; Mattias Roser; Michel Chrétien; Nabil G Seidah; Eckart Fleck; Mieczyslaw Marcinkiewicz
Coordinated regulation and colocalization of alphav integrin and its activating enzyme proprotein convertase PC5 in vivo.
Histochemistry and cell biology 2003;119(3):239-45.
2003: Kristof Graf; Kai Kappert; Philipp Stawowy; Johanna Bokemeyer; Florian Blaschke; Gunther Schmidt; Ulrich Kintscher; Stephan Goetze; Eckart Fleck
Statins regulate alpha2beta1-integrin expression and collagen I-dependent functions in human vascular smooth muscle cells.
Journal of cardiovascular pharmacology 2003;41(1):89-96.
2002: Stephan Goetze; Anne Bungenstock; Cornelia Czupalla; Friedrich Eilers; Philipp Stawowy; Ulrich Kintscher; Chantel Spencer-Hänsch; Kristof Graf; Bernd Nürnberg; Ronald E Law; Eckart Fleck; Michael Gräfe
Leptin induces endothelial cell migration through Akt, which is inhibited by PPARgamma-ligands.
Hypertension 2002;40(5):748-54.
2002: Florian Blaschke; Philipp Stawowy; Stephan Goetze; Oliver Hintz; Michael Gräfe; Ulrich Kintscher; Eckart Fleck; Kristof Graf
Hypoxia activates beta(1)-integrin via ERK 1/2 and p38 MAP kinase in human vascular smooth muscle cells.
Biochemical and biophysical research communications 2002;296(4):890-6.
2002: Florian Blaschke; Philipp Stawowy; Kai Kappert; Stephan Goetze; Ulrich Kintscher; Brigitte Wollert-Wulf; Eckart Fleck; Kristof Graf
Angiotensin II-augmented migration of VSMCs towards PDGF-BB involves Pyk2 and ERK 1/2 activation.
Basic research in cardiology 2002;97(4):334-42.
2002: Stephan Goetze; Friedrich Eilers; Anne Bungenstock; Ulrich Kintscher; Philipp Stawowy; Florian Blaschke; Kristof Graf; Ronald E Law; Eckart Fleck; Michael Gräfe
PPAR activators inhibit endothelial cell migration by targeting Akt.
Biochemical and biophysical research communications 2002;293(5):1431-7.
2002: Philipp Stawowy; Florian Blaschke; Peter Pfautsch; Stephan Goetze; Frank Lippek; Brigitte Wollert-Wulf; Eckart Fleck; Kristof Graf
Increased myocardial expression of osteopontin in patients with advanced heart failure.
European journal of heart failure 2002;4(2):139-46.
2002: Philipp Stawowy; Florian Blaschke; Adam Kilimnik; Stephan Goetze; Heike Kallisch; Michel Chrétien; Mieczyslaw Marcinkiewicz; Eckart Fleck; Kristof Graf
Proprotein convertase PC5 regulation by PDGF-BB involves PI3-kinase/p70(s6)-kinase activation in vascular smooth muscle cells.
Hypertension 2002;39(2 Pt 2):399-404.
2001: Stephan Goetze; Florian Blaschke; Philipp Stawowy; Dennis Bruemmer; C Spencer; Kristof Graf; Michael Gräfe; Ronald E Law; Eckart Fleck
TNFalpha inhibits insulin's antiapoptotic signaling in vascular smooth muscle cells.
Biochemical and biophysical research communications 2001;287(3):662-70.
2001: Philipp Stawowy; Jadwiga Marcinkiewicz; Kristof Graf; Nabil G Seidah; Michel Chrétien; E Fleck; Mieczyslaw Marcinkiewicz
Selective expression of the proprotein convertases furin, pc5, and pc7 in proliferating vascular smooth muscle cells of the rat aorta in vitro.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2001;49(3):323-32.
2000: Kristof Graf; M Neuss; Philipp Stawowy; Willa A Hsueh; Eckart Fleck; Ronald E Law
Angiotensin II and alpha(v)beta(3) integrin expression in rat neonatal cardiac fibroblasts.
Hypertension 2000;35(4):978-84.