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Gary Stein

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
274
Lian, Jane
263
Stein, Janet
229
van Wijnen, Andre
71
Montecino, Martin
68
Javed, Amjad
45
Zaidi, Sayyed
41
Pratap, Jitesh
29
Young, Daniel
27
Pockwinse, Shirwin
22
Owen, Thomas
22
Choi, Je-Yong
20
Hassan, Mohammad
19
Gutierrez, Soraya
19
Bortell, Rita
16
Lengner, Christopher

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Publications

TOP 3
Becker Klaus A; Stein Janet L; Lian Jane B; van Wijnen Andre J; Stein Gary S
Human embryonic stem cells are pre-mitotically committed to self-renewal and acquire a lengthened G1 phase upon lineage programming.
Pereira Barry P; Zhou Yefang; Gupta Anurag; Leong David T; Aung Khin Zarchi; Ling Ling; Pho Robert W H; Galindo Mario; Salto-Tellez Manuel; Stein Gary S; Cool Simon M; van Wijnen Andre J; Nathan Saminathan S
Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1).
San Martin Inga A; Varela Nelson; Gaete Marcia; Villegas Karina; Osorio Mariana; Tapia Julio C; Antonelli Marcelo; Mancilla Edna E; Pereira Barry P; Nathan Saminathan S; Lian Jane B; Stein Janet L; Stein Gary S; van Wijnen Andre J; Galindo Mario
Impaired cell cycle regulation of the osteoblast-related heterodimeric transcription factor Runx2-Cbfbeta in osteosarcoma cells.

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All Publications

2010: Becker Klaus A; Stein Janet L; Lian Jane B; van Wijnen Andre J; Stein Gary S
Human embryonic stem cells are pre-mitotically committed to self-renewal and acquire a lengthened G1 phase upon lineage programming.
Journal of cellular physiology 2010;222(1):103-10.
2009: Pereira Barry P; Zhou Yefang; Gupta Anurag; Leong David T; Aung Khin Zarchi; Ling Ling; Pho Robert W H; Galindo Mario; Salto-Tellez Manuel; Stein Gary S; Cool Simon M; van Wijnen Andre J; Nathan Saminathan S
Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1).
Journal of cellular physiology 2009;221(3):778-88.
2009: San Martin Inga A; Varela Nelson; Gaete Marcia; Villegas Karina; Osorio Mariana; Tapia Julio C; Antonelli Marcelo; Mancilla Edna E; Pereira Barry P; Nathan Saminathan S; Lian Jane B; Stein Janet L; Stein Gary S; van Wijnen Andre J; Galindo Mario
Impaired cell cycle regulation of the osteoblast-related heterodimeric transcription factor Runx2-Cbfbeta in osteosarcoma cells.
Journal of cellular physiology 2009;221(3):560-71.
2009: Zaidi Sayyed K; Dowdy Christopher R; van Wijnen Andre J; Lian Jane B; Raza Azra; Stein Janet L; Croce Carlo M; Stein Gary S
Altered Runx1 subnuclear targeting enhances myeloid cell proliferation and blocks differentiation by activating a miR-24/MKP-7/MAPK network.
Cancer research 2009;69(21):8249-55.
2009: Zhang Ying; Lian Jane B; Stein Janet L; van Wijnen Andre J; Stein Gary S
The Notch-responsive transcription factor Hes-1 attenuates osteocalcin promoter activity in osteoblastic cells.
Journal of cellular biochemistry 2009;108(3):651-9.
2009: Wixted John J; Fanning Paul J; Gaur Tripti; O'Connell Shannon L; Silva Jason; Mason-Savas April; Ayers David C; Stein Gary S; Lian Jane B
Enhanced fracture repair by leukotriene antagonism is characterized by increased chondrocyte proliferation and early bone formation: a novel role of the cysteinyl LT-1 receptor.
Journal of cellular physiology 2009;221(1):31-9.
2009: Pratap Jitesh; Imbalzano Karen M; Underwood Jean M; Cohet Nathalie; Gokul Karthiga; Akech Jacqueline; van Wijnen Andre J; Stein Janet L; Imbalzano Anthony N; Nickerson Jeffrey A; Lian Jane B; Stein Gary S
Ectopic runx2 expression in mammary epithelial cells disrupts formation of normal acini structure: implications for breast cancer progression.
Cancer research 2009;69(17):6807-14.
2009: Filion Tera M; Qiao Meng; Ghule Prachi N; Mandeville Matthew; van Wijnen Andre J; Stein Janet L; Lian Jane B; Altieri Dario C; Stein Gary S
Survival responses of human embryonic stem cells to DNA damage.
Journal of cellular physiology 2009;220(3):586-92.
2009: Cruzat Fernando; Henriquez Berta; Villagra Alejandro; Hepp Matias; Lian Jane B; van Wijnen Andre J; Stein Janet L; Imbalzano Anthony N; Stein Gary S; Montecino Martin
SWI/SNF-independent nuclease hypersensitivity and an increased level of histone acetylation at the P1 promoter accompany active transcription of the bone master gene Runx2.
Biochemistry 2009;48(30):7287-95.
2009: Altieri Dario C; Languino Lucia R; Lian Jane B; Stein Janet L; Leav Irwin; van Wijnen Andre J; Jiang Zhong; Stein Gary S
Prostate cancer regulatory networks.
Journal of cellular biochemistry 2009;107(5):845-52.
2009: Xie Ronglin; Medina Ricardo; Zhang Ying; Hussain Sadiq; Colby Jennifer; Ghule Prachi; Sundararajan Sakthi; Keeler Marilyn; Liu Li-Jun; van der Deen Margaretha; Mitra Partha; Lian Jane B; Rivera-Perez Jaime A; Jones Stephen N; Stein Janet L; van Wijnen Andre J; Stein Gary S
The histone gene activator HINFP is a nonredundant cyclin E/CDK2 effector during early embryonic cell cycles.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(30):12359-64.
2009: Smith Kelly P; Luong Mai X; Stein Gary S
Pluripotency: toward a gold standard for human ES and iPS cells.
Journal of cellular physiology 2009;220(1):21-9.
2009: Gaur Tripti; Wixted John J; Hussain Sadiq; O'Connell Shannon L; Morgan Elise F; Ayers David C; Komm Barry S; Bodine Peter V; Stein Gary S; Lian Jane B
Secreted frizzled related protein 1 is a target to improve fracture healing.
Journal of cellular physiology 2009;220(1):174-81.
2009: Ghule Prachi N; Dominski Zbigniew; Lian Jane B; Stein Janet L; van Wijnen Andre J; Stein Gary S
The subnuclear organization of histone gene regulatory proteins and 3' end processing factors of normal somatic and embryonic stem cells is compromised in selected human cancer cell types.
Journal of cellular physiology 2009;220(1):129-35.
2009: Teplyuk Nadiya M; Zhang Ying; Lou Yang; Hawse John R; Hassan Mohammad Q; Teplyuk Viktor I; Pratap Jitesh; Galindo Mario; Stein Janet L; Stein Gary S; Lian Jane B; van Wijnen Andre J
The osteogenic transcription factor runx2 controls genes involved in sterol/steroid metabolism, including CYP11A1 in osteoblasts.
Molecular endocrinology (Baltimore, Md.) 2009;23(6):849-61.
2009: Li Zhaoyong; Hassan Mohammad Q; Jafferji Mohammed; Aqeilan Rami I; Garzon Ramiro; Croce Carlo M; van Wijnen Andre J; Stein Janet L; Stein Gary S; Lian Jane B
Biological functions of miR-29b contribute to positive regulation of osteoblast differentiation.
The Journal of biological chemistry 2009;284(23):15676-84.
2009: Song Jie; Xu Jianwen; Filion Tera; Saiz Eduardo; Tomsia Antoni P; Lian Jane B; Stein Gary S; Ayers David C; Bertozzi Carolyn R
Elastomeric high-mineral content hydrogel-hydroxyapatite composites for orthopedic applications.
Journal of biomedical materials research. Part A 2009;89(4):1098-107.
2009: Teplyuk Nadiya M; Haupt Larisa M; Ling Ling; Dombrowski Christian; Mun Foong Kin; Nathan Saminathan S; Lian Jane B; Stein Janet L; Stein Gary S; Cool Simon M; van Wijnen Andre J
The osteogenic transcription factor Runx2 regulates components of the fibroblast growth factor/proteoglycan signaling axis in osteoblasts.
Journal of cellular biochemistry 2009;107(1):144-54.
2009: Mitra Partha; Ghule Prachi N; van der Deen Margaretha; Medina Ricardo; Xie Rong-Lin; Holmes William F; Ye Xin; Nakayama Keiichi I; Harper J Wade; Stein Janet L; Stein Gary S; van Wijnen Andre J
CDK inhibitors selectively diminish cell cycle controlled activation of the histone H4 gene promoter by p220NPAT and HiNF-P.
Journal of cellular physiology 2009;219(2):438-48.
2009: Kuo Ya-Huei; Zaidi Sayyed K; Gornostaeva Svetlana; Komori Toshihisa; Stein Gary S; Castilla Lucio H
Runx2 induces acute myeloid leukemia in cooperation with Cbfbeta-SMMHC in mice.
Blood 2009;113(14):3323-32.
2009: Pande Sandhya; Ali Syed A; Dowdy Christopher; Zaidi Sayyed K; Ito Kosei; Ito Yoshiaki; Montecino Martin A; Lian Jane B; Stein Janet L; van Wijnen Andre J; Stein Gary S
Subnuclear targeting of the Runx3 tumor suppressor and its epigenetic association with mitotic chromosomes.
Journal of cellular physiology 2009;218(3):473-9.
2009: Aqeilan Rami I; Hagan John P; de Bruin Alain; Rawahneh Maysoon; Salah Zaidoun; Gaudio Eugenio; Siddiqui Hasan; Volinia Stefano; Alder Hansjuerg; Lian Jane B; Stein Gary S; Croce Carlo M
Targeted ablation of the WW domain-containing oxidoreductase tumor suppressor leads to impaired steroidogenesis.
Endocrinology 2009;150(3):1530-5.
2009: Stein Gary S; Zaidi Sayyed K; Stein Janet L; Lian Jane B; van Wijnen Andre J; Montecino Martin; Young Daniel W; Javed Amjad; Pratap Jitesh; Choi Je-Yong; Ali Syed A; Pande Sandhya; Hassan Mohammad Q
Organization, integration, and assembly of genetic and epigenetic regulatory machinery in nuclear microenvironments: implications for biological control in cancer.
Annals of the New York Academy of Sciences 2009;1155():4-14.
2009: Stein Gary S; Zaidi Sayyed K; Stein Janet L; Lian Jane B; van Wijnen Andre J; Montecino Martin; Young Daniel W; Javed Amjad; Pratap Jitesh; Choi Je-Yong; Ali Syed A; Pande Sandhya; Hassan Mohammad Q
Transcription-factor-mediated epigenetic control of cell fate and lineage commitment.
Biochemistry and cell biology = Biochimie et biologie cellulaire 2009;87(1):1-6.
2009: Lou Yang; Javed Amjad; Hussain Sadiq; Colby Jennifer; Frederick Dana; Pratap Jitesh; Xie Ronglin; Gaur Tripti; van Wijnen Andre J; Jones Stephen N; Stein Gary S; Lian Jane B; Stein Janet L
A Runx2 threshold for the cleidocranial dysplasia phenotype.
Human molecular genetics 2009;18(3):556-68.
2009: Stuardo Marcela; Martinez Milka; Hidalgo Karla; Montecino Martin; Javed Amjad; Lian Jane B; Stein Gary S; Stein Janet L; Gutiérrez Soraya E
Altered chromatin modifications in AML1/RUNX1 breakpoint regions involved in (8;21) translocation.
Journal of cellular physiology 2009;218(2):343-9.
2009: Zhang Ying; Hassan Mohammad Q; Xie Rong-Lin; Hawse John R; Spelsberg Thomas C; Montecino Martin; Stein Janet L; Lian Jane B; van Wijnen Andre J; Stein Gary S
Co-stimulation of the bone-related Runx2 P1 promoter in mesenchymal cells by SP1 and ETS transcription factors at polymorphic purine-rich DNA sequences (Y-repeats).
The Journal of biological chemistry 2009;284(5):3125-35.
2009: Javed Amjad; Afzal Faiza; Bae Jong-Sup; Gutierrez Soraya; Zaidi Kaleem; Pratap Jitesh; van Wijnen Andre J; Stein Janet L; Stein Gary S; Lian Jane B
Specific residues of RUNX2 are obligatory for formation of BMP2-induced RUNX2-SMAD complex to promote osteoblast differentiation.
Cells, tissues, organs 2009;189(1-4):133-7.
2009: Hassan Mohammad Q; Saini Sharanjot; Gordon Jonathan A R; van Wijnen Andre J; Montecino Martin; Stein Janet L; Stein Gary S; Lian Jane B
Molecular switches involving homeodomain proteins, HOXA10 and RUNX2 regulate osteoblastogenesis.
Cells, tissues, organs 2009;189(1-4):122-5.
2008: Bakshi Rachit; Zaidi Sayyed K; Pande Sandhya; Hassan Mohammad Q; Young Daniel W; Montecino Martin; Lian Jane B; van Wijnen Andre J; Stein Janet L; Stein Gary S
The leukemogenic t(8;21) fusion protein AML1-ETO controls rRNA genes and associates with nucleolar-organizing regions at mitotic chromosomes.
Journal of cell science 2008;121(Pt 23):3981-90.
2008: Ghule Prachi N; Dominski Zbigniew; Yang Xiao-Cui; Marzluff William F; Becker Klaus A; Harper J Wade; Lian Jane B; Stein Janet L; van Wijnen Andre J; Stein Gary S
Staged assembly of histone gene expression machinery at subnuclear foci in the abbreviated cell cycle of human embryonic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(44):16964-9.
2008: Medina Ricardo; Buck Timothy; Zaidi Sayyed K; Miele-Chamberland Angela; Lian Jane B; Stein Janet L; van Wijnen Andre J; Stein Gary S
The histone gene cell cycle regulator HiNF-P is a unique zinc finger transcription factor with a novel conserved auxiliary DNA-binding motif.
Biochemistry 2008;47(44):11415-23.
2008: Pratap Jitesh; Wixted John J; Gaur Tripti; Zaidi Sayyed K; Dobson Jason; Gokul Karthiga Devi; Hussain Sadiq; van Wijnen Andre J; Stein Janet L; Stein Gary S; Lian Jane B
Runx2 transcriptional activation of Indian Hedgehog and a downstream bone metastatic pathway in breast cancer cells.
Cancer research 2008;68(19):7795-802.
2008: Luong Mai X; Smith Kelly P; Stein Gary S
Human embryonic stem cell registries: value, challenges and opportunities.
Journal of cellular biochemistry 2008;105(3):625-32.
2008: Zhang Ying; Hassan Mohammad Q; Li Zhao-Yong; Stein Janet L; Lian Jane B; van Wijnen Andre J; Stein Gary S
Intricate gene regulatory networks of helix-loop-helix (HLH) proteins support regulation of bone-tissue related genes during osteoblast differentiation.
Journal of cellular biochemistry 2008;105(2):487-96.
2008: Teplyuk Nadiya M; Galindo Mario; Teplyuk Viktor I; Pratap Jitesh; Young Daniel W; Lapointe David; Javed Amjad; Stein Janet L; Lian Jane B; Stein Gary S; van Wijnen Andre J
Runx2 regulates G protein-coupled signaling pathways to control growth of osteoblast progenitors.
The Journal of biological chemistry 2008;283(41):27585-97.
2008: Trevant Brune; Gaur Tripti; Hussain Sadiq; Symons John; Komm Barry S; Bodine Peter V N; Stein Gary S; Lian Jane B
Expression of secreted frizzled related protein 1, a Wnt antagonist, in brain, kidney, and skeleton is dispensable for normal embryonic development.
Journal of cellular physiology 2008;217(1):113-26.
2008: Li Zhaoyong; Hassan Mohammad Q; Volinia Stefano; van Wijnen Andre J; Stein Janet L; Croce Carlo M; Lian Jane B; Stein Gary S
A microRNA signature for a BMP2-induced osteoblast lineage commitment program.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(37):13906-11.
2008: Stein Gary S; Davie James R; Knowlton J Randy; Zaidi Sayyed K
Nuclear microenvironments and cancer.
Journal of cellular biochemistry 2008;104(6):1949-52.
2008: Stein Gary S; Zaidi Sayyed K; Stein Janet L; Lian Jane B; van Wijnen Andre J; Montecino Martin; Young Daniel W; Javed Amjad; Pratap Jitesh; Choi Je-Yong; Ali Syed A; Pande Sandhya; Hassan Mohammad Q
Genetic and epigenetic regulation in nuclear microenvironments for biological control in cancer.
Journal of cellular biochemistry 2008;104(6):2016-26.
2008: Aqeilan Rami I; Hassan Mohammad Q; de Bruin Alain; Hagan John P; Volinia Stefano; Palumbo Titziana; Hussain Sadiq; Lee Suk-Hee; Gaur Tripti; Stein Gary S; Lian Jane B; Croce Carlo M
The WWOX tumor suppressor is essential for postnatal survival and normal bone metabolism.
The Journal of biological chemistry 2008;283(31):21629-39.
2008: Ali Syed A; Zaidi Sayyed K; Dacwag Caroline S; Salma Nunciada; Young Daniel W; Shakoori Abdul R; Montecino Martin A; Lian Jane B; van Wijnen Andre J; Imbalzano Anthony N; Stein Gary S; Stein Janet L
Phenotypic transcription factors epigenetically mediate cell growth control.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(18):6632-7.
2008: Medina Ricardo; Zaidi Sayyed K; Liu Chang-Gong; Stein Janet L; van Wijnen Andre J; Croce Carlo M; Stein Gary S
MicroRNAs 221 and 222 bypass quiescence and compromise cell survival.
Cancer research 2008;68(8):2773-80.
2008: Jensen Eric D; Niu Lingling; Caretti Giuseppina; Nicol Samantha M; Teplyuk Nadiya; Stein Gary S; Sartorelli Vittorio; van Wijnen Andre J; Fuller-Pace Frances V; Westendorf Jennifer J
p68 (Ddx5) interacts with Runx2 and regulates osteoblast differentiation.
Journal of cellular biochemistry 2008;103(5):1438-51.
2008: Javed Amjad; Bae Jong-Sup; Afzal Faiza; Gutierrez Soraya; Pratap Jitesh; Zaidi Sayyed K; Lou Yang; van Wijnen Andre J; Stein Janet L; Stein Gary S; Lian Jane B
Structural coupling of Smad and Runx2 for execution of the BMP2 osteogenic signal.
The Journal of biological chemistry 2008;283(13):8412-22.
2008: Carvallo Loreto; Henríquez Berta; Paredes Roberto; Olate Juan; Onate Sergio; van Wijnen Andre J; Lian Jane B; Stein Gary S; Stein Janet L; Montecino Martin
1alpha,25-dihydroxy vitamin D3-enhanced expression of the osteocalcin gene involves increased promoter occupancy of basal transcription regulators and gradual recruitment of the 1alpha,25-dihydroxy vitamin D3 receptor-SRC-1 coactivator complex.
Journal of cellular physiology 2008;214(3):740-9.
2008: George Kerri L; Saltman Laura H; Stein Gary S; Lian Jane B; Zurier Robert B
Ajulemic acid, a nonpsychoactive cannabinoid acid, suppresses osteoclastogenesis in mononuclear precursor cells and induces apoptosis in mature osteoclast-like cells.
Journal of cellular physiology 2008;214(3):714-20.
2008: Pockwinse Shirwin M; Zaidi Sayyed K; Medina Ricardo F; Bakshi Rachit; Kota Krishna P; Ali Syed A; Young Daniel W; Nickerson Jeffery A; Javed Amjad; Montecino Martin; van Wijnen Andre J; Lian Jane B; Stein Janet L; Stein Gary S
In situ nuclear organization of regulatory machinery.
Methods in molecular biology (Clifton, N.J.) 2008;455():239-59.
2008: van der Deen Margaretha; Hassan Mohammad Q; Pratap Jitesh; Teplyuk Nadiya M; Young Daniel W; Javed Amjad; Zaidi Sayyed K; Lian Jane B; Montecino Martin; Stein Janet L; Stein Gary S; van Wijnen Andre J
Chromatin immunoprecipitation assays: application of ChIP-on-chip for defining dynamic transcriptional mechanisms in bone cells.
Methods in molecular biology (Clifton, N.J.) 2008;455():165-76.
2008: Montecino Martin; Stein Gary S; Stein Janet L; Lian Jane B; van Wijnen Andre J; Carvallo Loreto; Marcellini Sylvain; Cruzat Fernando; Arriagada Gloria
Vitamin D control of gene expression: temporal and spatial parameters for organization of the regulatory machinery.
Critical reviews in eukaryotic gene expression 2008;18(2):163-72.
2007: Zaidi Sayyed K; Pande Sandhya; Pratap Jitesh; Gaur Tripti; Grigoriu Simina; Ali Syed A; Stein Janet L; Lian Jane B; van Wijnen Andre J; Stein Gary S
Runx2 deficiency and defective subnuclear targeting bypass senescence to promote immortalization and tumorigenic potential.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(50):19861-6.
2007: Stein Gary S
Gene expression in nuclear microenvironments for biological control and cancer.
Cancer biology & therapy 2007;6(11):1817-21.
2007: Medina Ricardo; van der Deen Margaretha; Miele-Chamberland Angela; Xie Rong-Lin; van Wijnen Andre J; Stein Janet L; Stein Gary S
The HiNF-P/p220NPAT cell cycle signaling pathway controls nonhistone target genes.
Cancer research 2007;67(21):10334-42.
2007: Xie Rong-Lin; Liu Lijun; Mitra Partha; Stein Janet L; van Wijnen Andre J; Stein Gary S
Transcriptional activation of the histone nuclear factor P (HiNF-P) gene by HiNF-P and its cyclin E/CDK2 responsive co-factor p220NPAT defines a novel autoregulatory loop at the G1/S phase transition.
Gene 2007;402(1-2):94-102.
2007: Galindo Mario; Kahler Rachel A; Teplyuk Nadiya M; Stein Janet L; Lian Jane B; Stein Gary S; Westendorf Jennifer J; van Wijnen Andre J
Cell cycle related modulations in Runx2 protein levels are independent of lymphocyte enhancer-binding factor 1 (Lef1) in proliferating osteoblasts.
Journal of molecular histology 2007;38(5):501-6.
2007: Ghule Prachi N; Becker Klaus A; Harper J Wade; Lian Jane B; Stein Janet L; van Wijnen Andre J; Stein Gary S
Cell cycle dependent phosphorylation and subnuclear organization of the histone gene regulator p220(NPAT) in human embryonic stem cells.
Journal of cellular physiology 2007;213(1):9-17.
2007: Miele Angela; Medina Ricardo; van Wijnen Andre J; Stein Gary S; Stein Janet L
The interactome of the histone gene regulatory factor HiNF-P suggests novel cell cycle related roles in transcriptional control and RNA processing.
Journal of cellular biochemistry 2007;102(1):136-48.
2007: Montecino Martin; Stein Janet L; Stein Gary S; Lian Jane B; van Wijnen Andre J; Cruzat Fernando; Gutiérrez Soraya; Olate Juan; Marcellini Sylvain; Gutiérrez José L
Nucleosome organization and targeting of SWI/SNF chromatin-remodeling complexes: contributions of the DNA sequence.
Biochemistry and cell biology = Biochimie et biologie cellulaire 2007;85(4):419-25.
2007: Zaidi Sayyed K; Young Daniel W; Javed Amjad; Pratap Jitesh; Montecino Martin; van Wijnen Andre; Lian Jane B; Stein Janet L; Stein Gary S
Nuclear microenvironments in biological control and cancer.
Nature reviews. Cancer 2007;7(6):454-63.
2007: Bruna Carola; Arriagada Gloria; Lian Jane B; Stein Gary S; Bunster Marta; Martinez-Oyanedel Jose; Montecino Martin
Crystallization and preliminary X-ray analysis of a domain in the Runx2 transcription factor that interacts with the 1alpha,25 dihydroxy vitamin D3 receptor.
Journal of cellular biochemistry 2007;101(3):785-9.
2007: Hassan Mohammad Q; Tare Rahul; Lee Suk Hee; Mandeville Matthew; Weiner Brian; Montecino Martin; van Wijnen Andre J; Stein Janet L; Stein Gary S; Lian Jane B
HOXA10 controls osteoblastogenesis by directly activating bone regulatory and phenotypic genes.
Molecular and cellular biology 2007;27(9):3337-52.
2007: Mitra Partha; Xie Ronglin; Harper J Wade; Stein Janet L; Stein Gary S; van Wijnen Andre J
HiNF-P is a bifunctional regulator of cell cycle controlled histone H4 gene transcription.
Journal of cellular biochemistry 2007;101(1):181-91.
2007: Montecino Martin; Stein Gary S; Cruzat Fernando; Marcellini Sylvain; Stein Janet L; Lian Jane B; van Wijnen Andre J; Arriagada Gloria
An architectural perspective of vitamin D responsiveness.
Archives of biochemistry and biophysics 2007;460(2):293-9.
2007: Rajgopal Arun; Young Daniel W; Mujeeb Khawaja A; Stein Janet L; Lian Jane B; van Wijnen Andre J; Stein Gary S
Mitotic control of RUNX2 phosphorylation by both CDK1/cyclin B kinase and PP1/PP2A phosphatase in osteoblastic cells.
Journal of cellular biochemistry 2007;100(6):1509-17.
2007: Arriagada Gloria; Paredes Roberto; Olate Juan; van Wijnen Andre; Lian Jane B; Stein Gary S; Stein Janet L; Onate Sergio; Montecino Martin
Phosphorylation at serine 208 of the 1alpha,25-dihydroxy Vitamin D3 receptor modulates the interaction with transcriptional coactivators.
The Journal of steroid biochemistry and molecular biology 2007;103(3-5):425-9.
2007: Gutiérrez José; Paredes Roberto; Cruzat Fernando; Hill David A; van Wijnen Andre J; Lian Jane B; Stein Gary S; Stein Janet L; Imbalzano Anthony N; Montecino Martin
Chromatin remodeling by SWI/SNF results in nucleosome mobilization to preferential positions in the rat osteocalcin gene promoter.
The Journal of biological chemistry 2007;282(13):9445-57.
2007: Carvallo Loreto; Henriquez Berta; Olate Juan; van Wijnen Andre J; Lian Jane B; Stein Gary S; Onate Sergio; Stein Janet L; Montecino Martin
The 1alpha,25-dihydroxy Vitamin D3 receptor preferentially recruits the coactivator SRC-1 during up-regulation of the osteocalcin gene.
The Journal of steroid biochemistry and molecular biology 2007;103(3-5):420-4.
2007: Young Daniel W; Hassan Mohammad Q; Yang Xiao-Qing; Galindo Mario; Javed Amjad; Zaidi Sayyed K; Furcinitti Paul; Lapointe David; Montecino Martin; Lian Jane B; Stein Janet L; van Wijnen Andre J; Stein Gary S
Mitotic retention of gene expression patterns by the cell fate-determining transcription factor Runx2.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(9):3189-94.
2007: Becker Klaus A; Stein Janet L; Lian Jane B; van Wijnen Andre J; Stein Gary S
Establishment of histone gene regulation and cell cycle checkpoint control in human embryonic stem cells.
Journal of cellular physiology 2007;210(2):517-26.
2007: Bae Jong-Sup; Gutierrez Soraya; Narla Radhika; Pratap Jitesh; Devados Rajitha; van Wijnen Andre J; Stein Janet L; Stein Gary S; Lian Jane B; Javed Amjad
Reconstitution of Runx2/Cbfa1-null cells identifies a requirement for BMP2 signaling through a Runx2 functional domain during osteoblast differentiation.
Journal of cellular biochemistry 2007;100(2):434-49.
2007: Young Daniel W; Hassan Mohammad Q; Pratap Jitesh; Galindo Mario; Zaidi Sayyed K; Lee Suk-hee; Yang Xiaoqing; Xie Ronglin; Javed Amjad; Underwood Jean M; Furcinitti Paul; Imbalzano Anthony N; Penman Sheldon; Nickerson Jeffrey A; Montecino Martin A; Lian Jane B; Stein Janet L; van Wijnen Andre J; Stein Gary S
Mitotic occupancy and lineage-specific transcriptional control of rRNA genes by Runx2.
Nature 2007;445(7126):442-6.
2007: Stein Gary S; Lian Jane B; van Wijnen Andre J; Stein Janet L; Javed Amjad; Montecino Martin; Choi Je-Yong; Vradii Diana; Zaidi Sayyed K; Pratap Jitesh; Young Daniel
Organization of transcriptional regulatory machinery in nuclear microenvironments: implications for biological control and cancer.
Advances in enzyme regulation 2007;47():242-50.
2006: Medina Ricardo; van Wijnen Andre J; Stein Gary S; Stein Janet L
The histone gene transcription factor HiNF-P stabilizes its cell cycle regulatory co-activator p220NPAT.
Biochemistry 2006;45(51):15915-20.
2006: Pratap J; Lian J B; Javed A; Barnes G L; van Wijnen A J; Stein J L; Stein G S
Regulatory roles of Runx2 in metastatic tumor and cancer cell interactions with bone.
Cancer metastasis reviews 2006;25(4):589-600.
2006: Hassan Mohammad Q; Tare Rahul S; Lee Suk Hee; Mandeville Matthew; Morasso Maria I; Javed Amjad; van Wijnen Andre J; Stein Janet L; Stein Gary S; Lian Jane B
BMP2 commitment to the osteogenic lineage involves activation of Runx2 by DLX3 and a homeodomain transcriptional network.
The Journal of biological chemistry 2006;281(52):40515-26.
2006: Stein Gary S; van Wijnen André J; Stein Janet L; Lian Jane B; Montecino Martin; Zaidi Sayyed K; Braastad Corey
An architectural perspective of cell-cycle control at the G1/S phase cell-cycle transition.
Journal of cellular physiology 2006;209(3):706-10.
2006: Zaidi Sayyed K; Javed Amjad; Pratap Jitesh; Schroeder Tania M; J Westendorf Jennifer; Lian Jane B; van Wijnen Andre J; Stein Gary S; Stein Janet L
Alterations in intranuclear localization of Runx2 affect biological activity.
Journal of cellular physiology 2006;209(3):935-42.
2006: Becker Klaus A; Ghule Prachi N; Therrien Jaclyn A; Lian Jane B; Stein Janet L; van Wijnen Andre J; Stein Gary S
Self-renewal of human embryonic stem cells is supported by a shortened G1 cell cycle phase.
Journal of cellular physiology 2006;209(3):883-93.
2006: Bravo Soraya; Paredes Roberto; Izaurieta Pamela; Lian Jane B; Stein Janet L; Stein Gary S; Hinrichs Maria Victoria; Olate Juan; Aguayo Luis G; Montecino Martin
The classic receptor for 1alpha,25-dihydroxy vitamin D3 is required for non-genomic actions of 1alpha,25-dihydroxy vitamin D3 in osteosarcoma cells.
Journal of cellular biochemistry 2006;99(4):995-1000.
2006: Villagra Alejandro; Cruzat Fernando; Carvallo Loreto; Paredes Roberto; Olate Juan; van Wijnen Andre J; Stein Gary S; Lian Jane B; Stein Janet L; Imbalzano Anthony N; Montecino Martin
Chromatin remodeling and transcriptional activity of the bone-specific osteocalcin gene require CCAAT/enhancer-binding protein beta-dependent recruitment of SWI/SNF activity.
The Journal of biological chemistry 2006;281(32):22695-706.
2006: Gaur Tripti; Rich Lillian; Lengner Christopher J; Hussain Sadiq; Trevant Brune; Ayers David; Stein Janet L; Bodine Peter V N; Komm Barry S; Stein Gary S; Lian Jane B
Secreted frizzled related protein 1 regulates Wnt signaling for BMP2 induced chondrocyte differentiation.
Journal of cellular physiology 2006;208(1):87-96.
2006: Lian Jane B; Stein Gary S; Javed Amjad; van Wijnen Andre J; Stein Janet L; Montecino Martin; Hassan Mohammad Q; Gaur Tripti; Lengner Christopher J; Young Daniel W
Networks and hubs for the transcriptional control of osteoblastogenesis.
Reviews in endocrine & metabolic disorders 2006;7(1-2):1-16.
2006: Kahler Rachel A; Galindo Mario; Lian Jane; Stein Gary S; van Wijnen Andre J; Westendorf Jennifer J
Lymphocyte enhancer-binding factor 1 (Lef1) inhibits terminal differentiation of osteoblasts.
Journal of cellular biochemistry 2006;97(5):969-83.
2006: Lengner Christopher J; Steinman Heather A; Gagnon James; Smith Thomas W; Henderson Janet E; Kream Barbara E; Stein Gary S; Lian Jane B; Jones Stephen N
Osteoblast differentiation and skeletal development are regulated by Mdm2-p53 signaling.
The Journal of cell biology 2006;172(6):909-21.
2006: Pockwinse Shirwin M; Rajgopal Arun; Young Daniel W; Mujeeb Khwaja A; Nickerson Jeffrey; Javed Amjad; Redick Sambra; Lian Jane B; van Wijnen Andre J; Stein Janet L; Stein Gary S; Doxsey Stephen J
Microtubule-dependent nuclear-cytoplasmic shuttling of Runx2.
Journal of cellular physiology 2006;206(2):354-62.
2006: Vradii Diana; Wagner Stefan; Doan Diem N; Nickerson Jeffrey A; Montecino Martin; Lian Jane B; Stein Janet L; van Wijnen Andre J; Imbalzano Anthony N; Stein Gary S
Brg1, the ATPase subunit of the SWI/SNF chromatin remodeling complex, is required for myeloid differentiation to granulocytes.
Journal of cellular physiology 2006;206(1):112-8.
2005: Bodine Peter V N; Billiard Julia; Moran Robert A; Ponce-de-Leon Helga; McLarney Sean; Mangine Annamarie; Scrimo Melissa J; Bhat Ramesh A; Stauffer Barbara; Green Jack; Stein Gary S; Lian Jane B; Komm Barry S
The Wnt antagonist secreted frizzled-related protein-1 controls osteoblast and osteocyte apoptosis.
Journal of cellular biochemistry 2005;96(6):1212-30.
2005: Li Xiangen; Vradii Diana; Gutierrez Soraya; Lian Jane B; van Wijnen Andre J; Stein Janet L; Stein Gary S; Javed Amjad
Subnuclear targeting of Runx1 is required for synergistic activation of the myeloid specific M-CSF receptor promoter by PU.1.
Journal of cellular biochemistry 2005;96(4):795-809.
2005: Holmes William F; Braastad Corey D; Mitra Partha; Hampe Cornelia; Doenecke Detlef; Albig Werner; Stein Janet L; van Wijnen Andre J; Stein Gary S
Coordinate control and selective expression of the full complement of replication-dependent histone H4 genes in normal and cancer cells.
The Journal of biological chemistry 2005;280(45):37400-7.
2005: Pratap Jitesh; Javed Amjad; Languino Lucia R; van Wijnen Andre J; Stein Janet L; Stein Gary S; Lian Jane B
The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion.
Molecular and cellular biology 2005;25(19):8581-91.
2005: Gaur Tripti; Lengner Christopher J; Hovhannisyan Hayk; Bhat Ramesh A; Bodine Peter V N; Komm Barry S; Javed Amjad; van Wijnen Andre J; Stein Janet L; Stein Gary S; Lian Jane B
Canonical WNT signaling promotes osteogenesis by directly stimulating Runx2 gene expression.
The Journal of biological chemistry 2005;280(39):33132-40.
2005: Saltman Laura H; Javed Amjad; Ribadeneyra John; Hussain Sadiq; Young Daniel W; Osdoby Philip; Amcheslavsky Alla; van Wijnen Andre J; Stein Janet L; Stein Gary S; Lian Jane B; Bar-Shavit Zvi
Organization of transcriptional regulatory machinery in osteoclast nuclei: compartmentalization of Runx1.
Journal of cellular physiology 2005;204(3):871-80.
2005: Miele Angela; Braastad Corey D; Holmes William F; Mitra Partha; Medina Ricardo; Xie Ronglin; Zaidi Sayyed K; Ye Xin; Wei Yue; Harper J Wade; van Wijnen Andre J; Stein Janet L; Stein Gary S
HiNF-P directly links the cyclin E/CDK2/p220NPAT pathway to histone H4 gene regulation at the G1/S phase cell cycle transition.
Molecular and cellular biology 2005;25(14):6140-53.
2005: Afzal Faiza; Pratap Jitesh; Ito Kosei; Ito Yoshiaki; Stein Janet L; van Wijnen Andre J; Stein Gary S; Lian Jane B; Javed Amjad
Smad function and intranuclear targeting share a Runx2 motif required for osteogenic lineage induction and BMP2 responsive transcription.
Journal of cellular physiology 2005;204(1):63-72.
2005: Vradii Diana; Zaidi Sayyed K; Lian Jane B; van Wijnen Andre J; Stein Janet L; Stein Gary S
Point mutation in AML1 disrupts subnuclear targeting, prevents myeloid differentiation, and effects a transformation-like phenotype.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(20):7174-9.
2005: Galindo Mario; Pratap Jitesh; Young Daniel W; Hovhannisyan Hayk; Im Hee-Jeong; Choi Je-Yong; Lian Jane B; Stein Janet L; Stein Gary S; van Wijnen Andre J
The bone-specific expression of Runx2 oscillates during the cell cycle to support a G1-related antiproliferative function in osteoblasts.
The Journal of biological chemistry 2005;280(21):20274-85.
2005: Stein Gary S
Mechanogenomic control of DNA exposure and sequestration.
The American journal of pathology 2005;166(4):959-62.
2005: Lengner Christopher J; Hassan Mohammad Q; Serra Ryan W; Lepper Christoph; van Wijnen Andre J; Stein Janet L; Lian Jane B; Stein Gary S
Nkx3.2-mediated repression of Runx2 promotes chondrogenic differentiation.
The Journal of biological chemistry 2005;280(16):15872-9.
2005: Young Daniel W; Pratap Jitesh; Javed Amjad; Weiner Brian; Ohkawa Yasuyuki; van Wijnen Andre; Montecino Martin; Stein Gary S; Stein Janet L; Imbalzano Anthony N; Lian Jane B
SWI/SNF chromatin remodeling complex is obligatory for BMP2-induced, Runx2-dependent skeletal gene expression that controls osteoblast differentiation.
Journal of cellular biochemistry 2005;94(4):720-30.
2005: Zaidi Sayyed K; Young Daniel W; Choi Je-Yong; Pratap Jitesh; Javed Amjad; Montecino Martin; Stein Janet L; van Wijnen Andre J; Lian Jane B; Stein Gary S
The dynamic organization of gene-regulatory machinery in nuclear microenvironments.
EMBO reports 2005;6(2):128-33.
2005: Javed Amjad; Barnes George L; Pratap Jitesh; Antkowiak Tomasz; Gerstenfeld Louis C; van Wijnen Andre J; Stein Janet L; Lian Jane B; Stein Gary S
Impaired intranuclear trafficking of Runx2 (AML3/CBFA1) transcription factors in breast cancer cells inhibits osteolysis in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(5):1454-9.
2005: Stein Gary S; Lian Jane B; Stein Janet L; van Wijnen Andre J; Javed Amjad; Montecino Martin; Zaidi Sayyed K; Young Daniel W; Choi Je-Yong; Pratap Jitesh
Combinatorial organization of the transcriptional regulatory machinery in biological control and cancer.
Advances in enzyme regulation 2005;45():136-54.
2004: Braastad Corey D; Hovhannisyan Hayk; van Wijnen Andre J; Stein Janet L; Stein Gary S
Functional characterization of a human histone gene cluster duplication.
Gene 2004;342(1):35-40.
2004: Hassan Mohammad Q; Javed Amjad; Morasso Maria I; Karlin Jeremy; Montecino Martin; van Wijnen Andre J; Stein Gary S; Stein Janet L; Lian Jane B
Dlx3 transcriptional regulation of osteoblast differentiation: temporal recruitment of Msx2, Dlx3, and Dlx5 homeodomain proteins to chromatin of the osteocalcin gene.
Molecular and cellular biology 2004;24(20):9248-61.
2004: Paredes Roberto; Arriagada Gloria; Cruzat Fernando; Villagra Alejandro; Olate Juan; Zaidi Kaleem; van Wijnen Andre; Lian Jane B; Stein Gary S; Stein Janet L; Montecino Martin
Bone-specific transcription factor Runx2 interacts with the 1alpha,25-dihydroxyvitamin D3 receptor to up-regulate rat osteocalcin gene expression in osteoblastic cells.
Molecular and cellular biology 2004;24(20):8847-61.
2004: Young Daniel W; Zaidi Sayyed K; Furcinitti Paul S; Javed Amjad; van Wijnen Andre J; Stein Janet L; Lian Jane B; Stein Gary S
Quantitative signature for architectural organization of regulatory factors using intranuclear informatics.
Journal of cell science 2004;117(Pt 21):4889-96.
2004: Gutierrez Soraya; Liu Jilin; Javed Amjad; Montecino Martin; Stein Gary S; Lian Jane B; Stein Janet L
The vitamin D response element in the distal osteocalcin promoter contributes to chromatin organization of the proximal regulatory domain.
The Journal of biological chemistry 2004;279(42):43581-8.
2004: Zaidi Sayyed K; Young Daniel W; Choi Je-Yong; Pratap Jitesh; Javed Amjad; Montecino Martin; Stein Janet L; Lian Jane B; van Wijnen Andre J; Stein Gary S
Intranuclear trafficking: organization and assembly of regulatory machinery for combinatorial biological control.
The Journal of biological chemistry 2004;279(42):43363-6.
2004: Lengner Christopher J; Lepper Christoph; van Wijnen Andre J; Stein Janet L; Stein Gary S; Lian Jane B
Primary mouse embryonic fibroblasts: a model of mesenchymal cartilage formation.
Journal of cellular physiology 2004;200(3):327-33.
2004: Barnes George L; Hebert Kerri E; Kamal Mohammad; Javed Amjad; Einhorn Thomas A; Lian Jane B; Stein Gary S; Gerstenfeld Louis C
Fidelity of Runx2 activity in breast cancer cells is required for the generation of metastases-associated osteolytic disease.
Cancer research 2004;64(13):4506-13.
2004: Stein Gary S; Lian Jane B; van Wijnen Andre J; Stein Janet L; Montecino Martin; Javed Amjad; Zaidi Sayyed K; Young Daniel W; Choi Je-Yong; Pockwinse Shirwin M
Runx2 control of organization, assembly and activity of the regulatory machinery for skeletal gene expression.
Oncogene 2004;23(24):4315-29.
2004: Bodine Peter V N; Zhao Weiguang; Kharode Yogendra P; Bex Frederick J; Lambert Andre-Jean; Goad Mary Beth; Gaur Tripti; Stein Gary S; Lian Jane B; Komm Barry S
The Wnt antagonist secreted frizzled-related protein-1 is a negative regulator of trabecular bone formation in adult mice.
Molecular endocrinology (Baltimore, Md.) 2004;18(5):1222-37.
2004: Zaidi Sayyed K; Sullivan Andrew J; Medina Ricardo; Ito Yoshiaki; van Wijnen Andre J; Stein Janet L; Lian Jane B; Stein Gary S
Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription.
The EMBO journal 2004;23(4):790-9.
2004: Stein Gary S; Lian Jane B; van Wijnen Andre J; Stein Janet L; Javed Amjad; Montecino Martin; Zaidi S Kaleem; Young Daniel; Choi Je-Yong; Gutierrez Soraya; Pockwinse Shirwin
Nuclear microenvironments support assembly and organization of the transcriptional regulatory machinery for cell proliferation and differentiation.
Journal of cellular biochemistry 2004;91(2):287-302.
2004: Javed Amjad; Zaidi Sayyed K; Gutierrez Soraya E; Lengner Christopher J; Harrington Kimberly S; Hovhannisyan Hayk; Cho Brian C; Pratap Jitesh; Pockwinse Shirwin M; Montecino Martin; van Wijnen André J; Lian Jane B; Stein Janet L; Stein Gary S
Protein-deoxyribonucleic acid interactions linked to gene expression: ligation-mediated polymerase chain reaction.
Methods in molecular biology (Clifton, N.J.) 2004;285():63-7.
2004: Javed Amjad; Zaidi Sayyed K; Gutierrez Soraya E; Lengner Christopher J; Harrington Kimberly S; Hovhannisyan Hayk; Cho Brian C; Pratap Jitesh; Pockwinse Shirwin M; Montecino Martin; van Wijnen André J; Lian Jane B; Stein Janet L; Stein Gary S
Protein-deoxyribonucleic acid interactions linked to gene expression: DNase I digestion.
Methods in molecular biology (Clifton, N.J.) 2004;285():57-62.
2004: Javed Amjad; Zaidi Sayyed K; Gutierrez Soraya E; Lengner Christopher J; Harrington Kimberly S; Hovhannisyan Hayk; Cho Brian C; Pratap Jitesh; Pockwinse Shirwin M; Montecino Martin; van Wijnen André J; Lian Jane B; Stein Janet L; Stein Gary S
Protein-deoxyribonucleic acid interactions linked to gene expression: electrophoretic mobility shift assay.
Methods in molecular biology (Clifton, N.J.) 2004;285():45-55.
2004: Javed Amjad; Zaidi Sayyed K; Gutierrez Soraya E; Lengner Christopher J; Harrington Kimberly S; Hovhannisyan Hayk; Cho Brian C; Pratap Jitesh; Pockwinse Shirwin M; Montecino Martin; van Wijnen André J; Lian Jane B; Stein Janet L; Stein Gary S
Chromatin immunoprecipitation.
Methods in molecular biology (Clifton, N.J.) 2004;285():41-4.
2004: Javed Amjad; Zaidi Sayyed K; Gutierrez Soraya E; Lengner Christopher J; Harrington Kimberly S; Hovhannisyan Hayk; Cho Brian C; Pratap Jitesh; Pockwinse Shirwin M; Montecino Martin; van Wijnen André J; Lian Jane B; Stein Janet L; Stein Gary S
Analysis of in vivo gene expression using epitope-tagged proteins.
Methods in molecular biology (Clifton, N.J.) 2004;285():37-40.
2004: Javed Amjad; Zaidi Sayyed K; Gutierrez Soraya E; Lengner Christopher J; Harrington Kimberly S; Hovhannisyan Hayk; Cho Brian C; Pratap Jitesh; Pockwinse Shirwin M; Montecino Martin; van Wijnen André J; Lian Jane B; Stein Janet L; Stein Gary S
Immunofluorescence analysis using epitope-tagged proteins: in vitro system.
Methods in molecular biology (Clifton, N.J.) 2004;285():33-6.
2004: Javed Amjad; Zaidi Sayyed K; Gutierrez Soraya E; Lengner Christopher J; Harrington Kimberly S; Hovhannisyan Hayk; Cho Brian C; Pratap Jitesh; Pockwinse Shirwin M; Montecino Martin; van Wijnen André J; Lian Jane B; Stein Janet L; Stein Gary S
In situ immunofluorescence analysis: analyzing RNA synthesis by 5-bromouridine-5'-triphosphate labeling.
Methods in molecular biology (Clifton, N.J.) 2004;285():29-31.
2004: Javed Amjad; Zaidi Sayyed K; Gutierrez Soraya E; Lengner Christopher J; Harrington Kimberly S; Hovhannisyan Hayk; Cho Brian C; Pratap Jitesh; Pockwinse Shirwin M; Montecino Martin; van Wijnen André J; Lian Jane B; Stein Janet L; Stein Gary S
In situ immunofluorescence analysis: immunofluorescence microscopy.
Methods in molecular biology (Clifton, N.J.) 2004;285():23-8.
2004: Stein G S; Stein J L; Lian J B; Van Wijnen A J; Montecino M; Javed A; Zaidi S K; Young D; Choi Je-Yong; Pockwinse S
Nuclear microenvironments: an architectural platform for the convergence and integration of transcriptional regulatory signals.
European journal of histochemistry : EJH 2004;48(1):65-76.
2004: Lian Jane B; Javed Amjad; Zaidi S Kaleem; Lengner Christopher; Montecino Martin; van Wijnen Andre J; Stein Janet L; Stein Gary S
Regulatory controls for osteoblast growth and differentiation: role of Runx/Cbfa/AML factors.
Critical reviews in eukaryotic gene expression 2004;14(1-2):1-41.
2003: Zaidi Sayyed K; Young Daniel W; Pockwinse Shirwin M; Javed Amjad; Lian Jane B; Stein Janet L; van Wijnen Andre J; Stein Gary S
Mitotic partitioning and selective reorganization of tissue-specific transcription factors in progeny cells.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(25):14852-7.
2003: Mitra Partha; Xie Rong-Lin; Medina Ricardo; Hovhannisyan Hayk; Zaidi S Kaleem; Wei Yue; Harper J Wade; Stein Janet L; van Wijnen André J; Stein Gary S
Identification of HiNF-P, a key activator of cell cycle-controlled histone H4 genes at the onset of S phase.
Molecular and cellular biology 2003;23(22):8110-23.
2003: Stein Gary S; Zaidi Sayyed K; Braastad Corey D; Montecino Martin; van Wijnen Andre J; Choi Je-Yong; Stein Janet L; Lian Jane B; Javed Amjad
Functional architecture of the nucleus: organizing the regulatory machinery for gene expression, replication and repair.
Trends in cell biology 2003;13(11):584-92.
2003: Pratap Jitesh; Galindo Mario; Zaidi S Kaleem; Vradii Diana; Bhat Bheem M; Robinson John A; Choi Je-Yong; Komori Toshisha; Stein Janet L; Lian Jane B; Stein Gary S; van Wijnen Andre J
Cell growth regulatory role of Runx2 during proliferative expansion of preosteoblasts.
Cancer research 2003;63(17):5357-62.
2003: Gupta Sunita; Luong Mai X; Bleuming Sylvia A; Miele Angela; Luong Michael; Young Daniel; Knudsen Erik S; Van Wijnen Andre J; Stein Janet L; Stein Gary S
Tumor suppressor pRB functions as a co-repressor of the CCAAT displacement protein (CDP/cut) to regulate cell cycle controlled histone H4 transcription.
Journal of cellular physiology 2003;196(3):541-56.
2003: Bidinger Bonnie; Torres Roxabella; Rossetti Ronald G; Brown Lisa; Beltre Rosa; Burstein Sumner; Lian Jane B; Stein Gary S; Zurier Robert B
Ajulemic acid, a nonpsychoactive cannabinoid acid, induces apoptosis in human T lymphocytes.
Clinical immunology (Orlando, Fla.) 2003;108(2):95-102.
2003: Lian Jane B; Balint Eva; Javed Amjad; Drissi Hicham; Vitti Regan; Quinlan Edward J; Zhang Lina; Van Wijnen Andre J; Stein Janet L; Speck Nancy; Stein Gary S
Runx1/AML1 hematopoietic transcription factor contributes to skeletal development in vivo.
Journal of cellular physiology 2003;196(2):301-11.
2003: Xie Rong-Lin; Gupta Sunita; Miele Angela; Shiffman Dov; Stein Janet L; Stein Gary S; van Wijnen Andre J
The tumor suppressor interferon regulatory factor 1 interferes with SP1 activation to repress the human CDK2 promoter.
The Journal of biological chemistry 2003;278(29):26589-96.
2003: Lian J B; Stein G S
The temporal and spatial subnuclear organization of skeletal gene regulatory machinery: integrating multiple levels of transcriptional control.
Calcified tissue international 2003;72(6):631-7.
2003: Barnes George L; Javed Amjad; Waller Sylvan M; Kamal Mohammad H; Hebert Kerri E; Hassan Mohammad Q; Bellahcene Akeila; Van Wijnen Andre J; Young Marian F; Lian Jane B; Stein Gary S; Gerstenfeld Louis C
Osteoblast-related transcription factors Runx2 (Cbfa1/AML3) and MSX2 mediate the expression of bone sialoprotein in human metastatic breast cancer cells.
Cancer research 2003;63(10):2631-7.
2003: Balint Eva; Lapointe David; Drissi Hicham; van der Meijden Caroline; Young Daniel W; van Wijnen Andre J; Stein Janet L; Stein Gary S; Lian Jane B
Phenotype discovery by gene expression profiling: mapping of biological processes linked to BMP-2-mediated osteoblast differentiation.
Journal of cellular biochemistry 2003;89(2):401-26.
2003: Sierra Jose; Villagra Alejandro; Paredes Roberto; Cruzat Fernando; Gutierrez Soraya; Javed Amjad; Arriagada Gloria; Olate Juan; Imschenetzky Maria; Van Wijnen Andre J; Lian Jane B; Stein Gary S; Stein Janet L; Montecino Martin
Regulation of the bone-specific osteocalcin gene by p300 requires Runx2/Cbfa1 and the vitamin D3 receptor but not p300 intrinsic histone acetyltransferase activity.
Molecular and cellular biology 2003;23(9):3339-51.
2003: Shen Jiali; Hovhannisyan Hayk; Lian Jane B; Montecino Martin A; Stein Gary S; Stein Janet L; Van Wijnen Andre J
Transcriptional induction of the osteocalcin gene during osteoblast differentiation involves acetylation of histones h3 and h4.
Molecular endocrinology (Baltimore, Md.) 2003;17(4):743-56.
2003: Stein Gary S; Lian Jane B; Stein Janet L; van Wijnen André J; Montecino Martin; Pratap Jitesh; Choi Je; Zaidi S Kaleem; Javed Amjad; Gutierrez Soraya; Harrington Kimberly; Shen Jiali; Young Daniel
Intranuclear organization of RUNX transcriptional regulatory machinery in biological control of skeletogenesis and cancer.
Blood cells, molecules & diseases 2003;30(2):170-6.
2003: Hovhannisyan Hayk; Cho Brian; Mitra Partha; Montecino Martin; Stein Gary S; Van Wijnen Andre J; Stein Janet L
Maintenance of open chromatin and selective genomic occupancy at the cell cycle-regulated histone H4 promoter during differentiation of HL-60 promyelocytic leukemia cells.
Molecular and cellular biology 2003;23(4):1460-9.
2003: Stein Gary S; Lian Jane B; Stein Janet L; Wijnen André J van; Montecino Martin; Javed Amjad; Pratap Jitesh; Choi Je; Zaidi S Kaleem; Gutierrez Soraya; Harrington Kimberly; Shen Jiali; Young Daniel
Intranuclear trafficking of transcription factors: Requirements for vitamin D-mediated biological control of gene expression.
Journal of cellular biochemistry 2003;88(2):340-55.
2003: Lian J B; Stein G S
Runx2/Cbfa1: a multifunctional regulator of bone formation.
Current pharmaceutical design 2003;9(32):2677-85.
2003: Stein Gary S; Lian Jane B; Montecino Martin; Stein Janet L; van Wijnen André J; Javed Amjad; Pratap Jitesh; Choi Je; Zaidi S Kaleem; Gutierrez Soraya; Harrington Kimberly; Shen Jiali; Young Daniel; Pockwinse Shirwin
Nuclear microenvironments support physiological control of gene expression.
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 2003;11(5):527-36.
2003: Stein Gary S; Lian Jane B; Stein Janet L; van Wijnen André J; Choi Je Y; Pratap Jitesh; Zaidi S Kaleem
Temporal and spatial parameters of skeletal gene expression: targeting RUNX factors and their coregulatory proteins to subnuclear domains.
Connective tissue research 2003;44 Suppl 1():149-53.
2003: Lian Jane B; Stein Janet L; Stein Gary S; van Wijnen André J; Montecino Martin; Javed Amjad; Gutierrez Soraya; Shen Jiali; Zaidi S Kaleem; Drissi Hicham
Runx2/Cbfa1 functions: diverse regulation of gene transcription by chromatin remodeling and co-regulatory protein interactions.
Connective tissue research 2003;44 Suppl 1():141-8.
2002: Barseguian Karina; Lutterbach Bart; Hiebert Scott W; Nickerson Jeffrey; Lian Jane B; Stein Janet L; van Wijnen Andre J; Stein Gary S
Multiple subnuclear targeting signals of the leukemia-related AML1/ETO and ETO repressor proteins.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(24):15434-9.
2002: Westendorf Jennifer J; Zaidi S Kaleem; Cascino Jonathan E; Kahler Rachel; van Wijnen André J; Lian Jane B; Yoshida Minoru; Stein Gary S; Li Xiaodong
Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter.
Molecular and cellular biology 2002;22(22):7982-92.
2002: Harrington Kimberly S; Javed Amjad; Drissi Hicham; McNeil Sandra; Lian Jane B; Stein Janet L; Van Wijnen André J; Wang Yu-Li; Stein Gary S
Transcription factors RUNX1/AML1 and RUNX2/Cbfa1 dynamically associate with stationary subnuclear domains.
Journal of cell science 2002;115(Pt 21):4167-76.
2002: Lengner Christopher J; Drissi Hicham; Choi Je-Yong; van Wijnen Andre J; Stein Janet L; Stein Gary S; Lian Jane B
Activation of the bone-related Runx2/Cbfa1 promoter in mesenchymal condensations and developing chondrocytes of the axial skeleton.
Mechanisms of development 2002;114(1-2):167-70.
2002: Zaidi Sayyed K; Sullivan Andrew J; van Wijnen Andre J; Stein Janet L; Stein Gary S; Lian Jane B
Integration of Runx and Smad regulatory signals at transcriptionally active subnuclear sites.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(12):8048-53.
2002: van der Meijden Caroline M J; Lapointe David S; Luong Mai X; Peric-Hupkes Daniel; Cho Brian; Stein Janet L; van Wijnen Andre J; Stein Gary S
Gene profiling of cell cycle progression through S-phase reveals sequential expression of genes required for DNA replication and nucleosome assembly.
Cancer research 2002;62(11):3233-43.
2002: Shen Jiali; Montecino Martin; Lian Jane B; Stein Gary S; Van Wijnen Andre J; Stein Janet L
Histone acetylation in vivo at the osteocalcin locus is functionally linked to vitamin D-dependent, bone tissue-specific transcription.
The Journal of biological chemistry 2002;277(23):20284-92.
2002: Xie Rong-Lin; van Wijnen Andre J; van der Meijden Caroline M; Stein Janet L; Stein Gary S
Forced expression of the interferon regulatory factor 2 oncoprotein causes polyploidy and cell death in FDC-P1 myeloid hematopoietic progenitor cells.
Cancer research 2002;62(9):2510-5.
2002: Drissi Hicham; Pouliot Arlyssa; Koolloos Christian; Stein Janet L; Lian Jane B; Stein Gary S; van Wijnen André J
1,25-(OH)2-vitamin D3 suppresses the bone-related Runx2/Cbfa1 gene promoter.
Experimental cell research 2002;274(2):323-33.
2002: Luong Mai X; van der Meijden Caroline M; Xing DongXia; Hesselton Ruth; Monuki Edwin S; Jones Stephen N; Lian Jane B; Stein Janet L; Stein Gary S; Neufeld Ellis J; van Wijnen Andre J
Genetic ablation of the CDP/Cux protein C terminus results in hair cycle defects and reduced male fertility.
Molecular and cellular biology 2002;22(5):1424-37.
2002: Gutierrez Soraya; Javed Amjad; Tennant Daniel K; van Rees Monique; Montecino Martin; Stein Gary S; Stein Janet L; Lian Jane B
CCAAT/enhancer-binding proteins (C/EBP) beta and delta activate osteocalcin gene transcription and synergize with Runx2 at the C/EBP element to regulate bone-specific expression.
The Journal of biological chemistry 2002;277(2):1316-23.
2002: Drissi Hicham; Pouliot Arlyssa; Stein Janet L; van Wijnen Andre J; Stein Gary S; Lian Jane B
Identification of novel protein/DNA interactions within the promoter of the bone-related transcription factor Runx2/Cbfa1.
Journal of cellular biochemistry 2002;86(2):403-12.
2001: Zaidi S K; Javed A; Choi J Y; van Wijnen A J; Stein J L; Lian J B; Stein G S
A specific targeting signal directs Runx2/Cbfa1 to subnuclear domains and contributes to transactivation of the osteocalcin gene.
Journal of cell science 2001;114(Pt 17):3093-102.
2001: Mitra P; Vaughan P S; Stein J L; Stein G S; van Wijnen A J
Purification and functional analysis of a novel leucine-zipper/nucleotide-fold protein, BZAP45, stimulating cell cycle regulated histone H4 gene transcription.
Biochemistry 2001;40(35):10693-9.
2001: Banerjee C; Javed A; Choi J Y; Green J; Rosen V; van Wijnen A J; Stein J L; Lian J B; Stein G S
Differential regulation of the two principal Runx2/Cbfa1 n-terminal isoforms in response to bone morphogenetic protein-2 during development of the osteoblast phenotype.
Endocrinology 2001;142(9):4026-39.
2001: Choi J Y; Pratap J; Javed A; Zaidi S K; Xing L; Balint E; Dalamangas S; Boyce B; van Wijnen A J; Lian J B; Stein J L; Jones S N; Stein G S
Subnuclear targeting of Runx/Cbfa/AML factors is essential for tissue-specific differentiation during embryonic development.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(15):8650-5.
2001: Kim R D; Stein G S; Chari R S
Impact of cell swelling on proliferative signal transduction in the liver.
Journal of cellular biochemistry 2001;83(1):56-69.
2001: Xie R; van Wijnen A J; van Der Meijden C; Luong M X; Stein J L; Stein G S
The cell cycle control element of histone H4 gene transcription is maximally responsive to interferon regulatory factor pairs IRF-1/IRF-3 and IRF-1/IRF-7.
The Journal of biological chemistry 2001;276(21):18624-32.
2001: Javed A; Barnes G L; Jasanya B O; Stein J L; Gerstenfeld L; Lian J B; Stein G S
runt homology domain transcription factors (Runx, Cbfa, and AML) mediate repression of the bone sialoprotein promoter: evidence for promoter context-dependent activity of Cbfa proteins.
Molecular and cellular biology 2001;21(8):2891-905.
2001: Shopland L S; Byron M; Stein J L; Lian J B; Stein G S; Lawrence J B
Replication-dependent histone gene expression is related to Cajal body (CB) association but does not require sustained CB contact.
Molecular biology of the cell 2001;12(3):565-76.
2001: Prince M; Banerjee C; Javed A; Green J; Lian J B; Stein G S; Bodine P V; Komm B S
Expression and regulation of Runx2/Cbfa1 and osteoblast phenotypic markers during the growth and differentiation of human osteoblasts.
Journal of cellular biochemistry 2001;80(3):424-40.
2000: Staal A; Enserink J M; Stein J L; Stein G S; van Wijnen A J
Molecular characterization of celtix-1, a bromodomain protein interacting with the transcription factor interferon regulatory factor 2.
Journal of cellular physiology 2000;185(2):269-79.
2000: Hoffmann H; Green J; van Wijnen A J; Stein J L; Stein G S; Lian J B
Expression screening of factors binding to the osteocalcin bone-specific promoter element OC box I: isolation of a novel osteoblast differentiation-specific factor.
Journal of cellular biochemistry 2000;80(1):156-68.
2000: Drissi H; Luc Q; Shakoori R; Chuva De Sousa Lopes S; Choi J Y; Terry A; Hu M; Jones S; Neil J C; Lian J B; Stein J L; Van Wijnen A J; Stein G S
Transcriptional autoregulation of the bone related CBFA1/RUNX2 gene.
Journal of cellular physiology 2000;184(3):341-50.
2000: McNeil S; Javed A; Harrington K S; Lian J B; Stein J L; van Wijnen A J; Stein G S
Leukemia-associated AML1/ETO (8;21) chromosomal translocation protein increases the cellular representation of PML bodies.
Journal of cellular biochemistry 2000;79(1):103-12.
2000: Stein G S; van Wijnen A J; Stein J L; Lian J B; Montecino M; Choi J; Zaidi K; Javed A
Intranuclear trafficking of transcription factors: implications for biological control.
Journal of cell science 2000;113 ( Pt 14)():2527-33.
2000: Stein G S; Lian J B; Stein J L; van Wijnen A J
Bone tissue specific transcriptional control: options for targeting gene therapy to the skeleton.
Cancer 2000;88(12 Suppl):2899-902.
2000: Javed A; Guo B; Hiebert S; Choi J Y; Green J; Zhao S C; Osborne M A; Stifani S; Stein J L; Lian J B; van Wijnen A J; Stein G S
Groucho/TLE/R-esp proteins associate with the nuclear matrix and repress RUNX (CBF(alpha)/AML/PEBP2(alpha)) dependent activation of tissue-specific gene transcription.
Journal of cell science 2000;113 ( Pt 12)():2221-31.
2000: Stein G S; Montecino M; van Wijnen A J; Stein J L; Lian J B
Nuclear structure-gene expression interrelationships: implications for aberrant gene expression in cancer.
Cancer research 2000;60(8):2067-76.
2000: Gordon J A; Pockwinse S M; Stewart F M; Quesenberry P J; Nakamura T; Croce C M; Lian J B; Stein J L; van Wijnen A J; Stein G S
Modified intranuclear organization of regulatory factors in human acute leukemias: reversal after treatment.
Journal of cellular biochemistry 2000;77(1):30-43.
2000: Brown R S; Shalhoub V; Coulter S; Alex S; Joris I; De Vito W; Lian J; Stein G S
Developmental regulation of thyrotropin receptor gene expression in the fetal and neonatal rat thyroid: relation to thyroid morphology and to thyroid-specific gene expression.
Endocrinology 2000;141(1):340-5.
2000: Stein G S; van Wijnen A J; Stein J L; Lian J B; Montecino M; Zaidi K; Javed A
Subnuclear organization and trafficking of regulatory proteins: implications for biological control and cancer.
Journal of cellular biochemistry. Supplement 2000;Suppl 35():84-92.
1999: McNeil S; Zeng C; Harrington K S; Hiebert S; Lian J B; Stein J L; van Wijnen A J; Stein G S
The t(8;21) chromosomal translocation in acute myelogenous leukemia modifies intranuclear targeting of the AML1/CBFalpha2 transcription factor.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(26):14882-7.
1999: van Gurp M F; Pratap J; Luong M; Javed A; Hoffmann H; Giordano A; Stein J L; Neufeld E J; Lian J B; Stein G S; van Wijnen A J
The CCAAT displacement protein/cut homeodomain protein represses osteocalcin gene transcription and forms complexes with the retinoblastoma protein-related protein p107 and cyclin A.
Cancer research 1999;59(23):5980-8.
1999: Stein G S; van Wijnen A J; Stein J L; Lian J B; Javed A; McNeil S; Pockwinse S M
Insight into regulatory factor targeting to transcriptionally active subnuclear sites.
Experimental cell research 1999;253(1):110-6.
1999: Tang L; Guo B; Javed A; Choi J Y; Hiebert S; Lian J B; van Wijnen A J; Stein J L; Stein G S; Zhou G W
Crystal structure of the nuclear matrix targeting signal of the transcription factor acute myelogenous leukemia-1/polyoma enhancer-binding protein 2alphaB/core binding factor alpha2.
The Journal of biological chemistry 1999;274(47):33580-6.
1999: Javed A; Gutierrez S; Montecino M; van Wijnen A J; Stein J L; Stein G S; Lian J B
Multiple Cbfa/AML sites in the rat osteocalcin promoter are required for basal and vitamin D-responsive transcription and contribute to chromatin organization.
Molecular and cellular biology 1999;19(11):7491-500.
1999: Stein G S; Van Wijnen A J; Montecino M; Stein J L; Lian J B
Nuclear structure/gene expression interrelationships.
Journal of cellular physiology 1999;181(2):240-50.
1999: Last T J; van Wijnen A J; de Ridder M C; Stein G S; Stein J L
The homeodomain transcription factor CDP/cut interacts with the cell cycle regulatory element of histone H4 genes packaged into nucleosomes.
Molecular biology reports 1999;26(3):185-94.
1999: Drissi H; Hushka D; Aslam F; Nguyen Q; Buffone E; Koff A; van Wijnen A; Lian J B; Stein J L; Stein G S
The cell cycle regulator p27kip1 contributes to growth and differentiation of osteoblasts.
Cancer research 1999;59(15):3705-11.
1999: Hou Z; Nguyen Q; Frenkel B; Nilsson S K; Milne M; van Wijnen A J; Stein J L; Quesenberry P; Lian J B; Stein G S
Osteoblast-specific gene expression after transplantation of marrow cells: implications for skeletal gene therapy.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(13):7294-9.
1999: Last T J; van Wijnen A J; Birnbaum M J; Stein G S; Stein J L
Multiple interactions of the transcription factor YY1 with human histone H4 gene regulatory elements.
Journal of cellular biochemistry 1999;72(4):507-16.
1999: Nilsson S K; Dooner M S; Weier H U; Frenkel B; Lian J B; Stein G S; Quesenberry P J
Cells capable of bone production engraft from whole bone marrow transplants in nonablated mice.
The Journal of experimental medicine 1999;189(4):729-34.
1999: Montecino M; Frenkel B; van Wijnen A J; Lian J B; Stein G S; Stein J L
Chromatin hyperacetylation abrogates vitamin D-mediated transcriptional upregulation of the tissue-specific osteocalcin gene in vivo.
Biochemistry 1999;38(4):1338-45.
1999: Aslam F; McCabe L; Frenkel B; van Wijnen A J; Stein G S; Lian J B; Stein J L
AP-1 and vitamin D receptor (VDR) signaling pathways converge at the rat osteocalcin VDR element: requirement for the internal activating protein-1 site for vitamin D-mediated trans-activation.
Endocrinology 1999;140(1):63-70.
1999: Stein G S; van Wijnen A J; Stein J L; Lian J B
Interrelationships of transcriptional machinery with nuclear architecture.
Critical reviews in eukaryotic gene expression 1999;9(3-4):183-90.
1999: Stein G S; van Wijnen A J; Stein J L; Lian J B; McNeil S; Pockwinse S M
Transcriptional control within the three-dimensional context of nuclear architecture: requirements for boundaries and direction.
Journal of cellular biochemistry 1999;Suppl 32-33():24-31.
1999: Stein G S; van Wijnen A J; Stein J L; Lian J B; Pockwinse S H; McNeil S
Implications for interrelationships between nuclear architecture and control of gene expression under microgravity conditions.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1999;13 Suppl():S157-66.
1999: Lian J B; Stein G S; Stein J L; van Wijnen A J
Regulated expression of the bone-specific osteocalcin gene by vitamins and hormones.
Vitamins and hormones 1999;55():443-509.
1998: Aziz F; van Wijnen A J; Stein J L; Stein G S
HiNF-D (CDP-cut/CDC2/cyclin A/pRB-complex) influences the timing of IRF-2-dependent cell cycle activation of human histone H4 gene transcription at the G1/S phase transition.
Journal of cellular physiology 1998;177(3):453-64.
1998: van der Meijden C M; Vaughan P S; Staal A; Albig W; Doenecke D; Stein J L; Stein G S; van Wijnen A J
Selective expression of specific histone H4 genes reflects distinctions in transcription factor interactions with divergent H4 promoter elements.
Biochimica et biophysica acta 1998;1442(1):82-100.
1998: Choi J Y; van Wijnen A J; Aslam F; Leszyk J D; Stein J L; Stein G S; Lian J B; Penman S
Developmental association of the beta-galactoside-binding protein galectin-1 with the nuclear matrix of rat calvarial osteoblasts.
Journal of cell science 1998;111 ( Pt 20)():3035-43.
1998: Stein G S; van Wijnen A J; Stein J L; Lian J B; Pockwinse S; McNeil S
Interrelationships of nuclear structure and transcriptional control: functional consequences of being in the right place at the right time.
Journal of cellular biochemistry 1998;70(2):200-12.
1998: Lindenmuth D; van Wijnen A J; Penman S; Stein J L; Stein G S; Lian J B
TGF-beta1 modifications in nuclear matrix proteins of osteoblasts during differentiation.
Journal of cellular biochemistry 1998;69(3):291-303.
1998: Shalhoub V; Aslam F; Breen E; van Wijnen A; Bortell R; Stein G S; Stein J L; Lian J B
Multiple levels of steroid hormone-dependent control of osteocalcin during osteoblast differentiation: glucocorticoid regulation of basal and vitamin D stimulated gene expression.
Journal of cellular biochemistry 1998;69(2):154-68.
1998: Bodine P V; Henderson R A; Green J; Aronow M; Owen T; Stein G S; Lian J B; Komm B S
Estrogen receptor-alpha is developmentally regulated during osteoblast differentiation and contributes to selective responsiveness of gene expression.
Endocrinology 1998;139(4):2048-57.
1998: McNeil S; Guo B; Stein J L; Lian J B; Bushmeyer S; Seto E; Atchison M L; Penman S; van Wijnen A J; Stein G S
Targeting of the YY1 transcription factor to the nucleolus and the nuclear matrix in situ: the C-terminus is a principal determinant for nuclear trafficking.
Journal of cellular biochemistry 1998;68(4):500-10.
1998: Zeng C; McNeil S; Pockwinse S; Nickerson J; Shopland L; Lawrence J B; Penman S; Hiebert S; Lian J B; van Wijnen A J; Stein J L; Stein G S
Intranuclear targeting of AML/CBFalpha regulatory factors to nuclear matrix-associated transcriptional domains.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(4):1585-9.
1998: Aziz F; van Wijnen A J; Vaughan P S; Wu S; Shakoori A R; Lian J B; Soprano K J; Stein J L; Stein G S
The integrated activities of IRF-2 (HiNF-M), CDP/cut (HiNF-D) and H4TF-2 (HiNF-P) regulate transcription of a cell cycle controlled human histone H4 gene: mechanistic differences between distinct H4 genes.
Molecular biology reports 1998;25(1):1-12.
1998: Vaughan P S; van der Meijden C M; Aziz F; Harada H; Taniguchi T; van Wijnen A J; Stein J L; Stein G S
Cell cycle regulation of histone H4 gene transcription requires the oncogenic factor IRF-2.
The Journal of biological chemistry 1998;273(1):194-9.
1998: Lynch M P; Capparelli C; Stein J L; Stein G S; Lian J B
Apoptosis during bone-like tissue development in vitro.
Journal of cellular biochemistry 1998;68(1):31-49.
1998: Stein G S; van Wijnen A J; Stein J L; Lian J B; Pockwinse S M; McNeil S
Linkages of nuclear architecture to biological and pathological control of gene expression.
Journal of cellular biochemistry. Supplement 1998;30-31():220-31.
1998: Lian J B; Stein G S; Stein J L; van Wijnen A J
Osteocalcin gene promoter: unlocking the secrets for regulation of osteoblast growth and differentiation.
Journal of cellular biochemistry. Supplement 1998;30-31():62-72.
1998: Stein G S; van Wijnen A J; Stein J L; Lian J B
Nuclear structure--skeletal gene expression interrelationships.
Frontiers in bioscience : a journal and virtual library 1998;3():d849-64.
1997: Guo B; Stein J L; van Wijnen A J; Stein G S
ATF1 and CREB trans-activate a cell cycle regulated histone H4 gene at a distal nuclear matrix associated promoter element.
Biochemistry 1997;36(47):14447-55.
1997: Ryoo H M; Hoffmann H M; Beumer T; Frenkel B; Towler D A; Stein G S; Stein J L; van Wijnen A J; Lian J B
Stage-specific expression of Dlx-5 during osteoblast differentiation: involvement in regulation of osteocalcin gene expression.
Molecular endocrinology (Baltimore, Md.) 1997;11(11):1681-94.
1997: van Wijnen A J; Cooper C; Odgren P; Aziz F; De Luca A; Shakoori R A; Giordano A; Quesenberry P J; Lian J B; Stein G S; Stein J L
Cell cycle-dependent modifications in activities of pRb-related tumor suppressors and proliferation-specific CDP/cut homeodomain factors in murine hematopoietic progenitor cells.
Journal of cellular biochemistry 1997;66(4):512-23.
1997: Stein G S; Lian J B; van Wijnen A J; Stein J L
The osteocalcin gene: a model for multiple parameters of skeletal-specific transcriptional control.
Molecular biology reports 1997;24(3):185-96.
1997: Birnbaum M J; van Zundert B; Vaughan P S; Whitmarsh A J; van Wijnen A J; Davis R J; Stein G S; Stein J L
Phosphorylation of the oncogenic transcription factor interferon regulatory factor 2 (IRF2) in vitro and in vivo.
Journal of cellular biochemistry 1997;66(2):175-83.
1997: Smith E; Frenkel B; MacLachlan T K; Giordano A; Stein J L; Lian J B; Stein G S
Post-proliferative cyclin E-associated kinase activity in differentiated osteoblasts: inhibition by proliferating osteoblasts and osteosarcoma cells.
Journal of cellular biochemistry 1997;66(2):141-52.
1997: Lindenmuth D M; van Wijnen A J; Hiebert S; Stein J L; Lian J B; Stein G S
Subcellular partitioning of transcription factors during osteoblast differentiation: developmental association of the AML/CBF alpha/PEBP2 alpha-related transcription factor-NMP-2 with the nuclear matrix.
Journal of cellular biochemistry 1997;66(1):123-32.
1997: Banerjee C; McCabe L R; Choi J Y; Hiebert S W; Stein J L; Stein G S; Lian J B
Runt homology domain proteins in osteoblast differentiation: AML3/CBFA1 is a major component of a bone-specific complex.
Journal of cellular biochemistry 1997;66(1):1-8.
1997: Zeng C; van Wijnen A J; Stein J L; Meyers S; Sun W; Shopland L; Lawrence J B; Penman S; Lian J B; Stein G S; Hiebert S W
Identification of a nuclear matrix targeting signal in the leukemia and bone-related AML/CBF-alpha transcription factors.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(13):6746-51.
1997: Bodine P V; Green J; Harris H A; Bhat R A; Stein G S; Lian J B; Komm B S
Functional properties of a conditionally phenotypic, estrogen-responsive, human osteoblast cell line.
Journal of cellular biochemistry 1997;65(3):368-87.
1997: Vaughan P S; van Wijnen A J; Stein J L; Stein G S
Interferon regulatory factors: growth control and histone gene regulation--it's not just interferon anymore.
Journal of molecular medicine (Berlin, Germany) 1997;75(5):348-59.
1997: Lian J B; Shalhoub V; Aslam F; Frenkel B; Green J; Hamrah M; Stein G S; Stein J L
Species-specific glucocorticoid and 1,25-dihydroxyvitamin D responsiveness in mouse MC3T3-E1 osteoblasts: dexamethasone inhibits osteoblast differentiation and vitamin D down-regulates osteocalcin gene expression.
Endocrinology 1997;138(5):2117-27.
1997: Frenkel B; Capparelli C; Van Auken M; Baran D; Bryan J; Stein J L; Stein G S; Lian J B
Activity of the osteocalcin promoter in skeletal sites of transgenic mice and during osteoblast differentiation in bone marrow-derived stromal cell cultures: effects of age and sex.
Endocrinology 1997;138(5):2109-16.
1997: Pockwinse S M; Krockmalnic G; Doxsey S J; Nickerson J; Lian J B; van Wijnen A J; Stein J L; Stein G S; Penman S
Cell cycle independent interaction of CDC2 with the centrosome, which is associated with the nuclear matrix-intermediate filament scaffold.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(7):3022-7.
1997: Ryoo H M; van Wijnen A J; Stein J L; Lian J B; Stein G S
Detection of a proliferation specific gene during development of the osteoblast phenotype by mRNA differential display.
Journal of cellular biochemistry 1997;64(1):106-16.
1997: Guo B; Aslam F; van Wijnen A J; Roberts S G; Frenkel B; Green M R; DeLuca H; Lian J B; Stein G S; Stein J L
YY1 regulates vitamin D receptor/retinoid X receptor mediated transactivation of the vitamin D responsive osteocalcin gene.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(1):121-6.
1996: van Wijnen A J; van Gurp M F; de Ridder M C; Tufarelli C; Last T J; Birnbaum M; Vaughan P S; Giordano A; Krek W; Neufeld E J; Stein J L; Stein G S
CDP/cut is the DNA-binding subunit of histone gene transcription factor HiNF-D: a mechanism for gene regulation at the G1/S phase cell cycle transition point independent of transcription factor E2F.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(21):11516-21.
1996: McCabe L R; Banerjee C; Kundu R; Harrison R J; Dobner P R; Stein J L; Lian J B; Stein G S
Developmental expression and activities of specific fos and jun proteins are functionally related to osteoblast maturation: role of Fra-2 and Jun D during differentiation.
Endocrinology 1996;137(10):4398-408.
1996: Stein G S; Stein J L; Lian J B; van Wijnen A J; Montecino M
Functional interrelationships between nuclear structure and transcriptional control: contributions to regulation of cell cycle- and tissue-specific gene expression.
Journal of cellular biochemistry 1996;62(2):198-209.
1996: Hoffmann H M; Beumer T L; Rahman S; McCabe L R; Banerjee C; Aslam F; Tiro J A; van Wijnen A J; Stein J L; Stein G S; Lian J B
Bone tissue-specific transcription of the osteocalcin gene: role of an activator osteoblast-specific complex and suppressor hox proteins that bind the OC box.
Journal of cellular biochemistry 1996;61(2):310-24.
1996: Banerjee C; Hiebert S W; Stein J L; Lian J B; Stein G S
An AML-1 consensus sequence binds an osteoblast-specific complex and transcriptionally activates the osteocalcin gene.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(10):4968-73.
1996: Banerjee C; Stein J L; Van Wijnen A J; Frenkel B; Lian J B; Stein G S
Transforming growth factor-beta 1 responsiveness of the rat osteocalcin gene is mediated by an activator protein-1 binding site.
Endocrinology 1996;137(5):1991-2000.
1996: Tang K T; Capparelli C; Stein J L; Stein G S; Lian J B; Huber A C; Braverman L E; DeVito W J
Acidic fibroblast growth factor inhibits osteoblast differentiation in vitro: altered expression of collagenase, cell growth-related, and mineralization-associated genes.
Journal of cellular biochemistry 1996;61(1):152-66.
1996: Stein G S; Lian J B; Stein J L; Van Wijnen A J; Montecino M
Transcriptional control of osteoblast growth and differentiation.
Physiological reviews 1996;76(2):593-629.
1996: Frenkel B; Montecino M; Green J; Aslam F; Desai R; Banerjee C; Stein J L; Lian J B; Stein G S
Basal and vitamin D-responsive activity of the rat osteocalcin promoter in stably transfected osteosarcoma cells: requirement of upstream sequences for control by the proximal regulatory domain.
Endocrinology 1996;137(3):1080-88.
1996: Shalhoub V; Jackson M E; Paradise C; Stein G S; Lian J B; Marks S C
Heterogeneity of colony stimulating factor-1 gene expression in the skeleton of four osteopetrotic mutations in rats and mice.
Journal of cellular physiology 1996;166(2):340-50.
1996: Lian J B; Stein G S; Stein J L; Van Wijnen A; McCabe L; Banerjee C; Hoffmann H
The osteocalcin gene promoter provides a molecular blueprint for regulatory mechanisms controlling bone tissue formation: role of transcription factors involved in development.
Connective tissue research 1996;35(1-4):15-21.
1995: Birnbaum M J; van Wijnen A J; Odgren P R; Last T J; Suske G; Stein G S; Stein J L
Sp1 trans-activation of cell cycle regulated promoters is selectively repressed by Sp3.
Biochemistry 1995;34(50):16503-8.
1995: Smith E; Frenkel B; Schlegel R; Giordano A; Lian J B; Stein J L; Stein G S
Expression of cell cycle regulatory factors in differentiating osteoblasts: postproliferative up-regulation of cyclins B and E.
Cancer research 1995;55(21):5019-24.
1995: Guo B; Odgren P R; van Wijnen A J; Last T J; Nickerson J; Penman S; Lian J B; Stein J L; Stein G S
The nuclear matrix protein NMP-1 is the transcription factor YY1.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(23):10526-30.
1995: Merriman H L; van Wijnen A J; Hiebert S; Bidwell J P; Fey E; Lian J; Stein J; Stein G S
The tissue-specific nuclear matrix protein, NMP-2, is a member of the AML/CBF/PEBP2/runt domain transcription factor family: interactions with the osteocalcin gene promoter.
Biochemistry 1995;34(40):13125-32.
1995: Vaughan P S; Aziz F; van Wijnen A J; Wu S; Harada H; Taniguchi T; Soprano K J; Stein J L; Stein G S
Activation of a cell-cycle-regulated histone gene by the oncogenic transcription factor IRF-2.
Nature 1995;377(6547):362-5.
1995: Wright K L; Birnbaum M J; van Wijnen A J; Stein G S; Stein J L
Bipartite structure of the proximal promoter of a human H4 histone gene.
Journal of cellular biochemistry 1995;58(3):372-9.
1995: Aslam F; Shalhoub V; van Wijnen A J; Banerjee C; Bortell R; Shakoori A R; Litwack G; Stein J L; Stein G S; Lian J B
Contributions of distal and proximal promoter elements to glucocorticoid regulation of osteocalcin gene transcription.
Molecular endocrinology (Baltimore, Md.) 1995;9(6):679-90.
1995: Ramsey-Ewing A L; Bortell R; Stein G S; Stein J L
Histone H4 proximal promoter mediates a complex transcriptional response during differentiation of 3T3L1 adipocytes.
Journal of cellular physiology 1995;163(2):312-20.
1995: Menconi M J; Pockwinse S; Owen T A; Dasse K A; Stein G S; Lian J B
Properties of blood-contacting surfaces of clinically implanted cardiac assist devices: gene expression, matrix composition, and ultrastructural characterization of cellular linings.
Journal of cellular biochemistry 1995;57(3):557-73.
1995: Kroeger P E; van Wijnen A J; Pauli U; Wright K L; Stein G S; Stein J L
In vivo occupancy of histone gene proximal promoter elements reflects gene copy number-dependent titratable transactivation factors and cross-species compatibility of regulatory sequences.
Journal of cellular biochemistry 1995;57(2):191-207.
1995: Lynch M P; Stein J L; Stein G S; Lian J B
The influence of type I collagen on the development and maintenance of the osteoblast phenotype in primary and passaged rat calvarial osteoblasts: modification of expression of genes supporting cell growth, adhesion, and extracellular matrix mineralization.
Experimental cell research 1995;216(1):35-45.
1995: Pockwinse S M; Stein J L; Lian J B; Stein G S
Developmental stage-specific cellular responses to vitamin D and glucocorticoids during differentiation of the osteoblast phenotype: interrelationship of morphology and gene expression by in situ hybridization.
Experimental cell research 1995;216(1):244-60.
1995: Heinrichs A A; Bortell R; Bourke M; Lian J B; Stein G S; Stein J L
Proximal promoter binding protein contributes to developmental, tissue-restricted expression of the rat osteocalcin gene.
Journal of cellular biochemistry 1995;57(1):90-100.
1995: Stein G S; van Wijnen A J; Stein J; Lian J B; Montecino M
Contributions of nuclear architecture to transcriptional control.
International review of cytology 1995;162A():251-78.
1994: Breen E C; van Wijnen A J; Lian J B; Stein G S; Stein J L
In vivo occupancy of the vitamin D responsive element in the osteocalcin gene supports vitamin D-dependent transcriptional upregulation in intact cells.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(26):12902-6.
1994: Hoffmann H M; Catron K M; van Wijnen A J; McCabe L R; Lian J B; Stein G S; Stein J L
Transcriptional control of the tissue-specific, developmentally regulated osteocalcin gene requires a binding motif for the Msx family of homeodomain proteins.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(26):12887-91.
1994: Frenkel B; Montecino M; Stein J L; Lian J B; Stein G S
A composite intragenic silencer domain exhibits negative and positive transcriptional control of the bone-specific osteocalcin gene: promoter and cell type requirements.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(23):10923-7.
1994: Breen E C; Ignotz R A; McCabe L; Stein J L; Stein G S; Lian J B
TGF beta alters growth and differentiation related gene expression in proliferating osteoblasts in vitro, preventing development of the mature bone phenotype.
Journal of cellular physiology 1994;160(2):323-35.
1994: Barone L M; Aronow M A; Tassinari M S; Conlon D; Canalis E; Stein G S; Lian J B
Differential effects of warfarin on mRNA levels of developmentally regulated vitamin K dependent proteins, osteocalcin, and matrix GLA protein in vitro.
Journal of cellular physiology 1994;160(2):255-64.
1994: Jackson M E; Shalhoub V; Lian J B; Stein G S; Marks S C
Aberrant gene expression in cultured mammalian bone cells demonstrates an osteoblast defect in osteopetrosis.
Journal of cellular biochemistry 1994;55(3):366-72.
1994: van den Ent F M; van Wijnen A J; Lian J B; Stein J L; Stein G S
Cell cycle controlled histone H1, H3, and H4 genes share unusual arrangements of recognition motifs for HiNF-D supporting a coordinate promoter binding mechanism.
Journal of cellular physiology 1994;159(3):515-30.
1994: Shakoori A R; van Wijnen A J; Bortell R; Owen T A; Stein J L; Lian J B; Stein G S
Variations in vitamin D receptor transcription factor complexes associated with the osteocalcin gene vitamin D responsive element in osteoblasts and osteosarcoma cells.
Journal of cellular biochemistry 1994;55(2):218-29.
1994: Shalhoub V; Bortell R; Jackson M E; Marks S C; Stein J L; Lian J B; Stein G S
Transcriptionally active nuclei isolated from intact bone reflect modified levels of gene expression in skeletal development and pathology.
Journal of cellular biochemistry 1994;55(2):182-9.
1994: Jenis L G; Ongphiphadhanakul B; Braverman L E; Stein G S; Lian J B; Lew R; Baran D T
Responsiveness of gene expression markers of osteoblastic and osteoclastic activity to calcitonin in the appendicular and axial skeleton of the rat in vivo.
Calcified tissue international 1994;54(6):511-5.
1994: Ramsey-Ewing A; Van Wijnen A J; Stein G S; Stein J L
Delineation of a human histone H4 cell cycle element in vivo: the master switch for H4 gene transcription.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(10):4475-9.
1994: Stein G S; van Wijnen A J; Stein J L; Lian J B; Bidwell J P; Montecino M
Nuclear architecture supports integration of physiological regulatory signals for transcription of cell growth and tissue-specific genes during osteoblast differentiation.
Journal of cellular biochemistry 1994;55(1):4-15.
1994: Bidwell J P; van Wijnen A J; Fey E G; Merriman H; Penman S; Stein J L; Stein G S; Lian J B
Subnuclear distribution of the vitamin D receptor.
Journal of cellular biochemistry 1994;54(4):494-500.
1994: Stein G S; Stein J L; van Wijnen A J; Lian J B
Histone gene transcription: a model for responsiveness to an integrated series of regulatory signals mediating cell cycle control and proliferation/differentiation interrelationships.
Journal of cellular biochemistry 1994;54(4):393-404.
1994: Bortell R; Owen T A; Ignotz R; Stein G S; Stein J L
TGF beta 1 prevents the down-regulation of type I procollagen, fibronectin, and TGF beta 1 gene expression associated with 3T3-L1 pre-adipocyte differentiation.
Journal of cellular biochemistry 1994;54(2):256-63.
1994: Shalhoub V; Bettencourt B; Jackson M E; MacKay C A; Glimcher M J; Marks S C; Stein G S; Lian J B
Abnormalities of phosphoprotein gene expression in three osteopetrotic rat mutations: elevated mRNA transcripts, protein synthesis, and accumulation in bone of mutant animals.
Journal of cellular physiology 1994;158(1):110-20.
1994: Bidwell J P; Fey E G; van Wijnen A J; Penman S; Stein J L; Lian J B; Stein G S
Nuclear matrix proteins distinguish normal diploid osteoblasts from osteosarcoma cells.
Cancer research 1994;54(1):28-32.
1994: Kockx M; McCabe L; Stein J L; Lian J B; Stein G S
Influence of DNA replication inhibition on expression of cell growth and tissue-specific genes in osteoblasts and osteosarcoma cells.
Journal of cellular biochemistry 1994;54(1):47-55.
1993: Rahman S; Oberdorf A; Montecino M; Tanhauser S M; Lian J B; Stein G S; Laipis P J; Stein J L
Multiple copies of the bone-specific osteocalcin gene in mouse and rat.
Endocrinology 1993;133(6):3050-3.
1993: Ongphiphadhanakul B; Jenis L G; Braverman L E; Alex S; Stein G S; Lian J B; Baran D T
Etidronate inhibits the thyroid hormone-induced bone loss in rats assessed by bone mineral density and messenger ribonucleic acid markers of osteoblast and osteoclast function.
Endocrinology 1993;133(6):2502-7.
1993: Frenkel B; Mijnes J; Aronow M A; Zambetti G; Banerjee C; Stein J L; Lian J B; Stein G S
Position and orientation-selective silencer in protein-coding sequences of the rat osteocalcin gene.
Biochemistry 1993;32(49):13636-43.
1993: Heinrichs A A; Banerjee C; Bortell R; Owen T A; Stein J L; Stein G S; Lian J B
Identification and characterization of two proximal elements in the rat osteocalcin gene promoter that may confer species-specific regulation.
Journal of cellular biochemistry 1993;53(3):240-50.
1993: Jenis L G; Lian J B; Stein G S; Baran D T
1 alpha,25-dihydroxyvitamin D3-induced changes in intracellular pH in osteoblast-like cells modulate gene expression.
Journal of cellular biochemistry 1993;53(3):234-9.
1993: Heinrichs A A; Bortell R; Rahman S; Stein J L; Alnemri E S; Litwack G; Lian J B; Stein G S
Identification of multiple glucocorticoid receptor binding sites in the rat osteocalcin gene promoter.
Biochemistry 1993;32(42):11436-44.
1993: van Wijnen A J; Bidwell J P; Fey E G; Penman S; Lian J B; Stein J L; Stein G S
Nuclear matrix association of multiple sequence-specific DNA binding activities related to SP-1, ATF, CCAAT, C/EBP, OCT-1, and AP-1.
Biochemistry 1993;32(33):8397-402.
1993: Stein G S; Lian J B
Molecular mechanisms mediating proliferation/differentiation interrelationships during progressive development of the osteoblast phenotype.
Endocrine reviews 1993;14(4):424-42.
1993: Jenis L G; Waud C E; Stein G S; Lian J B; Baran D T
Effect of gallium nitrate in vitro and in normal rats.
Journal of cellular biochemistry 1993;52(3):330-6.
1993: Barone L M; Tassinari M S; Bortell R; Owen T A; Zerogian J; Gagne K; Stein G S; Lian J B
Inhibition of induced endochondral bone development in caffeine-treated rats.
Journal of cellular biochemistry 1993;52(2):171-82.
1993: van den Ent F M; van Wijnen A J; Last T J; Bortell R; Stein J L; Lian J B; Stein G S
Concerted control of multiple histone promoter factors during cell density inhibition of proliferation in osteosarcoma cells: reciprocal regulation of cell cycle-controlled and bone-related genes.
Cancer research 1993;53(10 Suppl):2399-409.
1993: Pockwinse S M; Lawrence J B; Singer R H; Stein J L; Lian J B; Stein G S
Gene expression at single cell resolution associated with development of the bone cell phenotype: ultrastructural and in situ hybridization analysis.
Bone 1993;14(3):347-52.
1993: Shakoori A R; Owen T A; Shalhoub V; Stein J L; Bustin M; Stein G S; Lian J B
Differential expression of the chromosomal high mobility group proteins 14 and 17 during the onset of differentiation in mammalian osteoblasts and promyelocytic leukemia cells.
Journal of cellular biochemistry 1993;51(4):479-87.
1993: Bidwell J P; Van Wijnen A J; Fey E G; Dworetzky S; Penman S; Stein J L; Lian J B; Stein G S
Osteocalcin gene promoter-binding factors are tissue-specific nuclear matrix components.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(8):3162-6.
1993: Bortell R; Owen T A; Shalhoub V; Heinrichs A; Aronow M A; Rochette-Egly C; Lutz Y; Stein J L; Lian J B; Stein G S
Constitutive transcription of the osteocalcin gene in osteosarcoma cells is reflected by altered protein-DNA interactions at promoter regulatory elements.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(6):2300-4.
1993: Owen T A; Bortell R; Shalhoub V; Heinrichs A; Stein J L; Stein G S; Lian J B
Postproliferative transcription of the rat osteocalcin gene is reflected by vitamin D-responsive developmental modifications in protein-DNA interactions at basal and enhancer promoter elements.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(4):1503-7.
1992: Shalhoub V; Conlon D; Tassinari M; Quinn C; Partridge N; Stein G S; Lian J B
Glucocorticoids promote development of the osteoblast phenotype by selectively modulating expression of cell growth and differentiation associated genes.
Journal of cellular biochemistry 1992;50(4):425-40.
1992: Chanoine J P; Stein G S; Braverman L E; Shalhoub V; Lian J B; Huber C A; DeVito W J
Acidic fibroblast growth factor modulates gene expression in the rat thyroid in vivo.
Journal of cellular biochemistry 1992;50(4):392-9.
1992: Bortell R; van Wijnen A J; Ramsey-Ewing A L; Stein G S; Stein J L
Differential regulation of H4 histone gene expression in 3T3-L1 pre-adipocytes during arrest of proliferation following contact inhibition or differentiation and its modulation by TGF beta 1.
Journal of cellular biochemistry 1992;50(1):62-72.
1992: De Vito W J; Chanoine J P; Alex S; Fang S L; Stone S; Huber C A; Shalhoub V; Lian J B; Stein G S; Braverman L E
Effect of in vivo administration of recombinant acidic fibroblast growth factor on thyroid function in the rat: induction of colloid goiter.
Endocrinology 1992;131(2):729-35.
1992: Pockwinse S M; Wilming L G; Conlon D M; Stein G S; Lian J B
Expression of cell growth and bone specific genes at single cell resolution during development of bone tissue-like organization in primary osteoblast cultures.
Journal of cellular biochemistry 1992;49(3):310-23.
1992: van Wijnen A J; van den Ent F M; Lian J B; Stein J L; Stein G S
Overlapping and CpG methylation-sensitive protein-DNA interactions at the histone H4 transcriptional cell cycle domain: distinctions between two human H4 gene promoters.
Molecular and cellular biology 1992;12(7):3273-87.
1992: Bortell R; Owen T A; Bidwell J P; Gavazzo P; Breen E; van Wijnen A J; DeLuca H F; Stein J L; Lian J B; Stein G S
Vitamin D-responsive protein-DNA interactions at multiple promoter regulatory elements that contribute to the level of rat osteocalcin gene expression.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(13):6119-23.
1992: Gerbaulet S P; van Wijnen A J; Aronin N; Tassinari M S; Lian J B; Stein J L; Stein G S
Downregulation of histone H4 gene transcription during postnatal development in transgenic mice and at the onset of differentiation in transgenically derived calvarial osteoblast cultures.
Journal of cellular biochemistry 1992;49(2):137-47.
1992: van der Houven van Oordt C W; van Wijnen A J; Carter R; Soprano K; Lian J B; Stein G S; Stein J L
Protein-DNA interactions at the H4-site III upstream transcriptional element of a cell cycle regulated histone H4 gene: differences in normal versus tumor cells.
Journal of cellular biochemistry 1992;49(1):93-110.
1992: Lian J B; Stein G S
Transcriptional control of vitamin D-regulated proteins.
Journal of cellular biochemistry 1992;49(1):37-45.
1992: Dworetzky S I; Wright K L; Fey E G; Penman S; Lian J B; Stein J L; Stein G S
Sequence-specific DNA-binding proteins are components of a nuclear matrix-attachment site.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(9):4178-82.
1992: van Wijnen A J; Bidwell J; Lian J B; Stein J L; Stein G S
Stairway assays: rapid localization of multiple protein/DNA interaction sites in gene-regulatory 5' regions.
BioTechniques 1992;12(3):400-7.
1992: Wright K L; Dell'Orco R T; van Wijnen A J; Stein J L; Stein G S
Multiple mechanisms regulate the proliferation-specific histone gene transcription factor HiNF-D in normal human diploid fibroblasts.
Biochemistry 1992;31(10):2812-8.
1992: Shakoori A R; Oberdorf A M; Owen T A; Weber L A; Hickey E; Stein J L; Lian J B; Stein G S
Expression of heat shock genes during differentiation of mammalian osteoblasts and promyelocytic leukemia cells.
Journal of cellular biochemistry 1992;48(3):277-87.
1992: Lian J B; Stein G S
Concepts of osteoblast growth and differentiation: basis for modulation of bone cell development and tissue formation.
Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists 1992;3(3):269-305.
1991: van Wijnen A J; Lian J B; Stein J L; Stein G S
Protein/DNA interactions involving ATF/AP1-, CCAAT-, and HiNF-D-related factors in the human H3-ST519 histone promoter: cross-competition with transcription regulatory sites in cell cycle controlled H4 and H1 histone genes.
Journal of cellular biochemistry 1991;47(4):337-51.
1991: Stein G S; Lian J B; Dworetzky S I; Owen T A; Bortell R; Bidwell J P; van Wijnen A J
Regulation of transcription-factor activity during growth and differentiation: involvement of the nuclear matrix in concentration and localization of promoter binding proteins.
Journal of cellular biochemistry 1991;47(4):300-5.
1991: Tassinari M S; Gerstenfeld L C; Stein G S; Lian J B
Effect of caffeine on parameters of osteoblast growth and differentiation of a mineralized extracellular matrix in vitro.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1991;6(10):1029-36.
1991: Schepmoes G; Breen E; Owen T A; Aronow M A; Stein G S; Lian J B
Influence of dexamethasone on the vitamin D-mediated regulation of osteocalcin gene expression.
Journal of cellular biochemistry 1991;47(2):184-96.
1991: Barone L M; Owen T A; Tassinari M S; Bortell R; Stein G S; Lian J B
Developmental expression and hormonal regulation of the rat matrix Gla protein (MGP) gene in chondrogenesis and osteogenesis.
Journal of cellular biochemistry 1991;46(4):351-65.
1991: van Wijnen A J; Owen T A; Holthuis J; Lian J B; Stein J L; Stein G S
Coordination of protein-DNA interactions in the promoters of human H4, H3, and H1 histone genes during the cell cycle, tumorigenesis, and development.
Journal of cellular physiology 1991;148(1):174-89.
1991: van Wijnen A J; Ramsey-Ewing A L; Bortell R; Owen T A; Lian J B; Stein J L; Stein G S
Transcriptional element H4-site II of cell cycle regulated human H4 histone genes is a multipartite protein/DNA interaction site for factors HiNF-D, HiNF-M, and HiNF-P: involvement of phosphorylation.
Journal of cellular biochemistry 1991;46(2):174-89.
1991: Shalhoub V; Jackson M E; Lian J B; Stein G S; Marks S C
Gene expression during skeletal development in three osteopetrotic rat mutations. Evidence for osteoblast abnormalities.
The Journal of biological chemistry 1991;266(15):9847-56.
1991: van Wijnen A J; Choi T K; Owen T A; Wright K L; Lian J B; Jaenisch R; Stein J L; Stein G S
Involvement of the cell cycle-regulated nuclear factor HiNF-D in cell growth control of a human H4 histone gene during hepatic development in transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(6):2573-7.
1991: Owen T A; Aronow M S; Barone L M; Bettencourt B; Stein G S; Lian J B
Pleiotropic effects of vitamin D on osteoblast gene expression are related to the proliferative and differentiated state of the bone cell phenotype: dependency upon basal levels of gene expression, duration of exposure, and bone matrix competency in normal rat osteoblast cultures.
Endocrinology 1991;128(3):1496-504.
1991: Morris T D; Weber L A; Hickey E; Stein G S; Stein J L
Changes in the stability of a human H3 histone mRNA during the HeLa cell cycle.
Molecular and cellular biology 1991;11(1):544-53.
1991: Lian J B; Stein G S; Bortell R; Owen T A
Phenotype suppression: a postulated molecular mechanism for mediating the relationship of proliferation and differentiation by Fos/Jun interactions at AP-1 sites in steroid responsive promoter elements of tissue-specific genes.
Journal of cellular biochemistry 1991;45(1):9-14.
1990: Bortell R; Barone L M; Tassinari M S; Lian J B; Stein G S
Gene expression during endochondral bone development: evidence for coordinate expression of transforming growth factor beta 1 and collagen type I.
Journal of cellular biochemistry 1990;44(2):81-91.
1990: Stein G S; Lian J B; Owen T A
Relationship of cell growth to the regulation of tissue-specific gene expression during osteoblast differentiation.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1990;4(13):3111-23.
1990: Owen T A; Holthuis J; Markose E; van Wijnen A J; Wolfe S A; Grimes S R; Lian J B; Stein G S
Modifications of protein-DNA interactions in the proximal promoter of a cell-growth-regulated histone gene during onset and progression of osteoblast differentiation.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(13):5129-33.
1990: Dworetzky S I; Fey E G; Penman S; Lian J B; Stein J L; Stein G S
Progressive changes in the protein composition of the nuclear matrix during rat osteoblast differentiation.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(12):4605-9.
1990: Owen T A; Aronow M; Shalhoub V; Barone L M; Wilming L; Tassinari M S; Kennedy M B; Pockwinse S; Lian J B; Stein G S
Progressive development of the rat osteoblast phenotype in vitro: reciprocal relationships in expression of genes associated with osteoblast proliferation and differentiation during formation of the bone extracellular matrix.
Journal of cellular physiology 1990;143(3):420-30.
1990: Aronow M A; Gerstenfeld L C; Owen T A; Tassinari M S; Stein G S; Lian J B
Factors that promote progressive development of the osteoblast phenotype in cultured fetal rat calvaria cells.
Journal of cellular physiology 1990;143(2):213-21.
1990: Markose E R; Stein J L; Stein G S; Lian J B
Vitamin D-mediated modifications in protein-DNA interactions at two promoter elements of the osteocalcin gene.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(5):1701-5.
1989: Stein G S; Stein J L; Lian J B; Van Wijnen A J; Wright K L; Pauli U
Modifications in molecular mechanisms associated with control of cell cycle regulated human histone gene expression during differentiation.
Cell biophysics 1989;15(3):201-23.
1989: van Wijnen A J; Wright K L; Lian J B; Stein J L; Stein G S
Human H4 histone gene transcription requires the proliferation-specific nuclear factor HiNF-D. Auxiliary roles for HiNF-C (Sp1-like) and HiNF-A (high mobility group-like).
The Journal of biological chemistry 1989;264(25):15034-42.
1989: Shalhoub V; Gerstenfeld L C; Collart D; Lian J B; Stein G S
Downregulation of cell growth and cell cycle regulated genes during chick osteoblast differentiation with the reciprocal expression of histone gene variants.
Biochemistry 1989;28(13):5318-22.
1989: Puchacz E; Lian J B; Stein G S; Wozney J; Huebner K; Croce C
Chromosomal localization of the human osteocalcin gene.
Endocrinology 1989;124(5):2648-50.
1989: Stein G S; Lian J B; Gerstenfeld L G; Shalhoub V; Aronow M; Owen T; Markose E
The onset and progression of osteoblast differentiation is functionally related to cellular proliferation.
Connective tissue research 1989;20(1-4):3-13.
1989: Lian J B; Stein G S; Stewart C; Puchacz E; Mackowiak S; Aronow M; Von Deck M; Shalhoub V
Osteocalcin: characterization and regulated expression of the rat gene.
Connective tissue research 1989;21(1-4):61-8; discussion 69.
1989: Marks S C; Mackowiak S; Shaloub V; Lian J B; Stein G S
Proliferation and differentiation of osteoblasts in osteopetrotic rats: modification in expression of genes encoding cell growth and extracellular matrix proteins.
Connective tissue research 1989;21(1-4):107-13; discussion 114-6.
1988: Collar D G; Wright K L; van Wijnen A J; Ramsey A L; Lian J; Stein J L; Stein G S
The human H1 histone gene FNC16 is functionally expressed in proliferating HeLa S3 cells and is down-regulated during terminal differentiation in HL60 cells.
The Journal of biological chemistry 1988;263(31):15860-3.
1988: van Wijnen A J; Massung R F; Stein J L; Stein G S
Human H1 histone gene promoter CCAAT box binding protein HiNF-B is a mosaic factor.
Biochemistry 1988;27(17):6534-41.
1988: Moreno M L; Pauli U; Chrysogelos S; Stein J L; Stein G S
Persistence of a micrococcal nuclease sensitive region spanning the promoter-coding region junction of a cell cycle regulated human H4 histone gene throughout the cell cycle.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1988;66(2):132-7.
1988: Lawrence J B; Singer R H; Villnave C A; Stein J L; Stein G S
Intracellular distribution of histone mRNAs in human fibroblasts studied by in situ hybridization.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(2):463-7.
1988: van Wijnen A J; Wright K L; Massung R F; Gerretsen M; Stein J L; Stein G S
Two target sites for protein binding in the promoter region of a cell cycle regulated human H1 histone gene.
Nucleic acids research 1988;16(2):571-92.
1987: Baumbach L L; Stein G S; Stein J L
Regulation of human histone gene expression: transcriptional and posttranscriptional control in the coupling of histone messenger RNA stability with DNA replication.
Biochemistry 1987;26(19):6178-87.
1987: Helms S R; van Wijnen A J; Kroeger P; Shiels A; Stewart C; Hirshman J; Stein J L; Stein G S
Identification of an enhancer-like element upstream from a cell cycle dependent human H4 histone gene.
Journal of cellular physiology 1987;132(3):552-8.
1986: Moreno M L; Chrysogelos S A; Stein G S; Stein J L
Reversible changes in the nucleosomal organization of a human H4 histone gene during the cell cycle.
Biochemistry 1986;25(19):5364-70.

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