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Janet Stein

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Sandhya Pande; Gillian Browne; Jane B Lian; Srivatsan Padmanabhan; Janet L Stein; Andre J van Wijnen; Sayyed K Zaidi; Gary S Stein
Oncogenic cooperation between PI3K/Akt signaling and transcription factor Runx2 promotes the invasive properties of metastatic breast cancer cells.
Hayk Hovhannisyan; Jane B Lian; Martin Montecino; Gary S Stein; Janet L Stein; Carlotta Glackin; Mohammad Q Hassan; Hai Wu; Ying Zhang; Andre J van Wijnen
Genomic occupancy of HLH, AP1 and Runx2 motifs within a nuclease sensitive site of the Runx2 gene.
Mohammad Q Hassan; Mohammad Jafferji; Zhaoyong Li; Yukiko Maeda; Gary S Stein; Janet L Stein; Hanna Taipaleenmaki; Andre J van Wijnen; Weibing Zhang; Carlo M Croce; Jonathan A R Gordon; Jane B Lian
miR-218 directs a Wnt signaling circuit to promote differentiation of osteoblasts and osteomimicry of metastatic cancer cells.

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2013: Sandhya Pande; Gillian Browne; Jane B Lian; Srivatsan Padmanabhan; Janet L Stein; Andre J van Wijnen; Sayyed K Zaidi; Gary S Stein
Oncogenic cooperation between PI3K/Akt signaling and transcription factor Runx2 promotes the invasive properties of metastatic breast cancer cells.
Journal of cellular physiology 2013;228(8):1784-92.
2013: Hayk Hovhannisyan; Jane B Lian; Martin Montecino; Gary S Stein; Janet L Stein; Carlotta Glackin; Mohammad Q Hassan; Hai Wu; Ying Zhang; Andre J van Wijnen
Genomic occupancy of HLH, AP1 and Runx2 motifs within a nuclease sensitive site of the Runx2 gene.
Journal of cellular physiology 2013;228(2):313-21.
2012: Mohammad Q Hassan; Mohammad Jafferji; Zhaoyong Li; Yukiko Maeda; Gary S Stein; Janet L Stein; Hanna Taipaleenmaki; Andre J van Wijnen; Weibing Zhang; Carlo M Croce; Jonathan A R Gordon; Jane B Lian
miR-218 directs a Wnt signaling circuit to promote differentiation of osteoblasts and osteomimicry of metastatic cancer cells.
The Journal of biological chemistry 2012;287(50):42084-92.
2012: Ricardo Medina; Martin Montecino; A Rasim Barutcu; Fernando Cruzat; Prachi N Ghule; Janet L Stein; Andre J van Wijnen; Gary S Stein
Epigenetic control of cell cycle-dependent histone gene expression is a principal component of the abbreviated pluripotent cell cycle.
Molecular and cellular biology 2012;32(19):3860-71.
2012: Sayyed K Zaidi; Christopher R Dowdy; Jane B Lian; Janet L Stein; Daniel J Trombly; Andre J van Wijnen; Gary S Stein
Epigenetic mechanisms in leukemia.
Advances in biological regulation 2012;52(3):369-76.
2012: Ying Zhang; Janet L Stein; Andre J van Wijnen; Rong-Lin Xie; Jonathan Gordon; Kimberly LeBlanc; Jane B Lian; Gary S Stein
Control of mesenchymal lineage progression by microRNAs targeting skeletal gene regulators Trps1 and Runx2.
The Journal of biological chemistry 2012;287(26):21926-35.
2012: Syed A Ali; Jason R Dobson; Jane B Lian; Janet L Stein; Andre J van Wijnen; Sayyed K Zaidi; Gary S Stein
A RUNX2-HDAC1 co-repressor complex regulates rRNA gene expression by modulating UBF acetylation.
Journal of cell science 2012;125(Pt 11):2732-9.
2012: Jane B Lian; Gary S Stein; Janet L Stein; Andre J van Wijnen; Tripti Gaur; Mohammad Q Hassan; Ying Zhang
MicroRNA control of bone formation and homeostasis.
Nature reviews. Endocrinology 2012;8(4):212-27.
2012: Margaretha van der Deen; Daniel W Young; Jacqueline Akech; Mario Galindo; Sneha Gupta; David Lapointe; Jane B Lian; Martin A Montecino; Gary S Stein; Janet L Stein; Andre J van Wijnen
Genomic promoter occupancy of runt-related transcription factor RUNX2 in Osteosarcoma cells identifies genes involved in cell adhesion and motility.
The Journal of biological chemistry 2012;287(7):4503-17.
2012: Gary S Stein; Janet L Stein; Andre van J Wijnen; Sayyed K Zaidi; Prachi Ghule; Rodrigo Grandy; Kristie Kapinas; Jane B Lian; Ricardo Medina; Martin Montecino; Klaus A Becker
The architectural organization of human stem cell cycle regulatory machinery.
Current pharmaceutical design 2012;18(13):1679-85.
2011: Berta Henriquez; Matias Hepp; Jane B Lian; Paola Merino; Hugo Sepulveda; Gary S Stein; Janet L Stein; Andre J van Wijnen; Martin Montecino
C/EBPβ binds the P1 promoter of the Runx2 gene and up-regulates Runx2 transcription in osteoblastic cells.
Journal of cellular physiology 2011;226(11):3043-52.
2011: Li-Jun Liu; Jaime Rivera-Perez; Gary S Stein; Janet L Stein; Sadiq Hussain; Stephen N Jones; Jane B Lian; Ronglin Xie; Andre J van Wijnen
Functional coupling of transcription factor HiNF-P and histone H4 gene expression during pre- and post-natal mouse development.
Gene 2011;483(1-2):1-10.
2011: Julie C Liu; Yang Lou; Gary S Stein; Janet L Stein; Heather A Steinman; Andre J van Wijnen; Brent Borodic; Jennifer L Colby; Tripti Gaur; Sadiq Hussain; Marci D Jones; Stephen N Jones; Christopher J Lengner; Jane B Lian
Runx2 protein expression utilizes the Runx2 P1 promoter to establish osteoprogenitor cell number for normal bone formation.
The Journal of biological chemistry 2011;286(34):30057-70.
2011: Ying Zhang; Carlo M Croce; Jane B Lian; Janet L Stein; Andre J van Wijnen; Rong-Lin Xie; Gary S Stein
A program of microRNAs controls osteogenic lineage progression by targeting transcription factor Runx2.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(24):9863-8.
2011: Sayyed K Zaidi; Daniel W Young; Martin Montecino; Andre J van Wijnen; Janet L Stein; Jane B Lian; Gary S Stein
Bookmarking the genome: maintenance of epigenetic information.
The Journal of biological chemistry 2011;286(21):18355-61.
2011: Prachi N Ghule; Ricardo Medina; Christopher J Lengner; Matthew Mandeville; Meng Qiao; Zbigniew Dominski; Jane B Lian; Janet L Stein; Andre J van Wijnen; Gary S Stein
Reprogramming the pluripotent cell cycle: restoration of an abbreviated G1 phase in human induced pluripotent stem (iPS) cells.
Journal of cellular physiology 2011;226(5):1149-56.
2011: Shirwin M Pockwinse; Krishna P Kota; Alexandre J C Quaresma; Anthony N Imbalzano; Jane B Lian; Andre J van Wijnen; Janet L Stein; Gary S Stein; Jeffrey A Nickerson
Live cell imaging of the cancer-related transcription factor RUNX2 during mitotic progression.
Journal of cellular physiology 2011;226(5):1383-9.
2011: Gary S Stein; Janet L Stein; Andre J van Wijnen; Jane B Lian; Sayyed K Zaidi; Jeffrey A Nickerson; Martin A Montecino; Daniel W Young
An architectural genetic and epigenetic perspective.
Integrative biology : quantitative biosciences from nano to macro 2011;3(4):297-303.
2011: Jonathan A R Gordon; Mohammad Q Hassan; Matthew Koss; Martin Montecino; Licia Selleri; Gary S Stein; Janet L Stein; Andre J van Wijnen; Jane B Lian
Epigenetic regulation of early osteogenesis and mineralized tissue formation by a HOXA10-PBX1-associated complex.
Cells, tissues, organs 2011;194(2-4):146-50.
2010: Jitesh Pratap; Jacqueline Akech; John J Wixted; Gabriela Szabo; Sadiq Hussain; Meghan E McGee-Lawrence; Xiaodong Li; Krystin Bedard; Robinder J Dhillon; Andre J van Wijnen; Janet L Stein; Gary S Stein; Jennifer J Westendorf; Jane B Lian
The histone deacetylase inhibitor, vorinostat, reduces tumor growth at the metastatic bone site and associated osteolysis, but promotes normal bone loss.
Molecular cancer therapeutics 2010;9(12):3210-20.
2010: Mohammad Q Hassan; Jonathan A R Gordon; Marcio M Beloti; Carlo M Croce; Andre J van Wijnen; Janet L Stein; Gary S Stein; Jane B Lian
A network connecting Runx2, SATB2, and the miR-23a~27a~24-2 cluster regulates the osteoblast differentiation program.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(46):19879-84.
2010: Rachit Bakshi; Mohammad Q Hassan; Jitesh Pratap; Jane B Lian; Martin Montecino; Andre J van Wijnen; Janet L Stein; Anthony N Imbalzano; Gary S Stein
The human SWI/SNF complex associates with RUNX1 to control transcription of hematopoietic target genes.
Journal of cellular physiology 2010;225(2):569-76.
2010: Sayyed K Zaidi; Daniel W Young; Martin Montecino; Jane B Lian; Janet L Stein; Andre J van Wijnen; Gary S Stein
Architectural epigenetics: mitotic retention of mammalian transcriptional regulatory information.
Molecular and cellular biology 2010;30(20):4758-66.
2010: Sayyed K Zaidi; Daniel W Young; Martin A Montecino; Jane B Lian; Andre J van Wijnen; Janet L Stein; Gary S Stein
Mitotic bookmarking of genes: a novel dimension to epigenetic control.
Nature reviews. Genetics 2010;11(8):583-9.
2010: Mohammad Q Hassan; Jonathan A R Gordon; Jane B Lian; Andre J van Wijnen; Janet L Stein; Gary S Stein
Ribonucleoprotein immunoprecipitation (RNP-IP): a direct in vivo analysis of microRNA-targets.
Journal of cellular biochemistry 2010;110(4):817-22.
2010: Jonathan A R Gordon; Mohammad Q Hassan; Sharanjot Saini; Martin Montecino; Andre J van Wijnen; Gary S Stein; Janet L Stein; Jane B Lian
Pbx1 represses osteoblastogenesis by blocking Hoxa10-mediated recruitment of chromatin remodeling factors.
Molecular and cellular biology 2010;30(14):3531-41.
2010: Tripti Gaur; Sadiq Hussain; Rajini Mudhasani; Isha Parulkar; Jennifer L Colby; Dana Frederick; Barbara E Kream; Andre J van Wijnen; Janet L Stein; Gary S Stein; Stephen N Jones; Jane B Lian
Dicer inactivation in osteoprogenitor cells compromises fetal survival and bone formation, while excision in differentiated osteoblasts increases bone mass in the adult mouse.
Developmental biology 2010;340(1):10-21.
2010: Christopher R Dowdy; Ronglin Xie; Dana Frederick; Sadiq Hussain; Sayyed K Zaidi; Diana Vradii; Amjad Javed; Xiangen Li; Stephen N Jones; Jane B Lian; Andre J van Wijnen; Janet L Stein; Gary S Stein
Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation.
Human molecular genetics 2010;19(6):1048-57.
2010: Syed A Ali; Sayyed K Zaidi; Jason R Dobson; Abdul Rauf Shakoori; Jane B Lian; Janet L Stein; Andre J van Wijnen; Gary S Stein
Transcriptional corepressor TLE1 functions with Runx2 in epigenetic repression of ribosomal RNA genes.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(9):4165-9.
2010: Margaretha van der Deen; Jacqueline Akech; Tao Wang; Thomas J Fitzgerald; Dario C Altieri; Lucia R Languino; Jane B Lian; Andre J van Wijnen; Janet L Stein; Gary S Stein
The cancer-related Runx2 protein enhances cell growth and responses to androgen and TGFbeta in prostate cancer cells.
Journal of cellular biochemistry 2010;109(4):828-37.
2010: J Akech; J J Wixted; K Bedard; Margaretha van der Deen; S Hussain; T A Guise; Andre J van Wijnen; Janet L Stein; Lucia R Languino; Dario C Altieri; J Pratap; Evan T Keller; Gary S Stein; Jane B Lian
Runx2 association with progression of prostate cancer in patients: mechanisms mediating bone osteolysis and osteoblastic metastatic lesions.
Oncogene 2010;29(6):811-21.
2010: Klaus A Becker; Prachi N Ghule; Jane B Lian; Janet L Stein; Andre J van Wijnen; Gary S Stein
Cyclin D2 and the CDK substrate p220(NPAT) are required for self-renewal of human embryonic stem cells.
Journal of cellular physiology 2010;222(2):456-64.
2010: Gloria Arriagada; Roberto Paredes; Andre J van Wijnen; Jane B Lian; Brigitte van Zundert; Gary S Stein; Janet L Stein; Martin Montecino
1alpha,25-dihydroxy vitamin D(3) induces nuclear matrix association of the 1alpha,25-dihydroxy vitamin D(3) receptor in osteoblasts independently of its ability to bind DNA.
Journal of cellular physiology 2010;222(2):336-46.
2010: Gary S Stein; Andre J van Wijnen; Anthony N Imbalzano; Martin Montecino; Sayyed K Zaidi; Jane B Lian; Jeffrey A Nickerson; Janet L Stein
Architectural genetic and epigenetic control of regulatory networks: compartmentalizing machinery for transcription and chromatin remodeling in nuclear microenvironments.
Critical reviews in eukaryotic gene expression 2010;20(2):149-55.
2010: Sayyed K Zaidi; Ricardo F Medina; Shirwin M Pockwinse; Rachit Bakshi; Krishna P Kota; Syed A Ali; Daniel W Young; Jeffrey A Nickerson; Amjad Javed; Martin Montecino; Andre J van Wijnen; Jane B Lian; Janet L Stein; Gary S Stein
Subnuclear localization and intranuclear trafficking of transcription factors.
Methods in molecular biology (Clifton, N.J.) 2010;647():77-93.
2010: Gary S Stein; Janet L Stein; Andre J van Wijnen; Jane B Lian; Martin Montecino; Carlo M Croce; Je-Yong Choi; Syed A Ali; Sandhya Pande; Mohammad Q Hassan; Sayyed K Zaidi; Daniel W Young
Transcription factor-mediated epigenetic regulation of cell growth and phenotype for biological control and cancer.
Advances in enzyme regulation 2010;50(1):160-7.
2010: Klaus A Becker; Janet L Stein; Jane B Lian; Andre J van Wijnen; Gary S Stein
Human embryonic stem cells are pre-mitotically committed to self-renewal and acquire a lengthened G1 phase upon lineage programming.
Journal of cellular physiology 2010;222(1):103-10.
2009: Inga A San Martin; Nelson Varela; Marcia Gaete; Karina Villegas; Mariana Osorio; Julio C Tapia; Marcelo Antonelli; Edna E Mancilla; Barry P Pereira; Saminathan S Nathan; Jane B Lian; Janet L Stein; Gary S Stein; Andre J van Wijnen; Mario Galindo
Impaired cell cycle regulation of the osteoblast-related heterodimeric transcription factor Runx2-Cbfbeta in osteosarcoma cells.
Journal of cellular physiology 2009;221(3):560-71.
2009: Sayyed K Zaidi; Christopher R Dowdy; Andre J van Wijnen; Jane B Lian; Azra Raza; Janet L Stein; Carlo M Croce; Gary S Stein
Altered Runx1 subnuclear targeting enhances myeloid cell proliferation and blocks differentiation by activating a miR-24/MKP-7/MAPK network.
Cancer research 2009;69(21):8249-55.
2009: Ying Zhang; Jane B Lian; Janet L Stein; Andre J van Wijnen; Gary S Stein
The Notch-responsive transcription factor Hes-1 attenuates osteocalcin promoter activity in osteoblastic cells.
Journal of cellular biochemistry 2009;108(3):651-9.
2009: Jitesh Pratap; Karen M Imbalzano; Jean M Underwood; Nathalie Cohet; Karthiga Gokul; Jacqueline Akech; Andre J van Wijnen; Janet L Stein; Anthony N Imbalzano; Jeffrey A Nickerson; Jane B Lian; Gary S Stein
Ectopic runx2 expression in mammary epithelial cells disrupts formation of normal acini structure: implications for breast cancer progression.
Cancer research 2009;69(17):6807-14.
2009: Tera M Filion; Meng Qiao; Prachi N Ghule; Matthew Mandeville; Andre J van Wijnen; Janet L Stein; Jane B Lian; Dario C Altieri; Gary S Stein
Survival responses of human embryonic stem cells to DNA damage.
Journal of cellular physiology 2009;220(3):586-92.
2009: Fernando Cruzat; Berta Henriquez; alejandro villagra; Matias Hepp; Jane B Lian; Andre J van Wijnen; Janet L Stein; Anthony N Imbalzano; Gary S Stein; Martin Montecino
SWI/SNF-independent nuclease hypersensitivity and an increased level of histone acetylation at the P1 promoter accompany active transcription of the bone master gene Runx2.
Biochemistry 2009;48(30):7287-95.
2009: Dario C Altieri; Lucia R Languino; Jane B Lian; Janet L Stein; Irwin Leav; Andre J van Wijnen; Zhong Jiang; Gary S Stein
Prostate cancer regulatory networks.
Journal of cellular biochemistry 2009;107(5):845-52.
2009: Ronglin Xie; Ricardo Medina; Ying Zhang; Sadiq Hussain; Jennifer Colby; Prachi Ghule; Sakthi Sundararajan; Marilyn Keeler; Li-Jun Liu; Margaretha van der Deen; Partha Mitra; Jane B Lian; Jaime A Rivera-Perez; Stephen N Jones; Janet L Stein; Andre J van Wijnen; Gary S Stein
The histone gene activator HINFP is a nonredundant cyclin E/CDK2 effector during early embryonic cell cycles.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(30):12359-64.
2009: Prachi N Ghule; Zbigniew Dominski; Jane B Lian; Janet L Stein; Andre J van Wijnen; Gary S Stein
The subnuclear organization of histone gene regulatory proteins and 3' end processing factors of normal somatic and embryonic stem cells is compromised in selected human cancer cell types.
Journal of cellular physiology 2009;220(1):129-35.
2009: Zhaoyong Li; Mohammad Q Hassan; Mohammed Jafferji; Rami I Aqeilan; Ramiro Garzon; Carlo M Croce; Andre J van Wijnen; Janet L Stein; Gary S Stein; Jane B Lian
Biological functions of miR-29b contribute to positive regulation of osteoblast differentiation.
The Journal of biological chemistry 2009;284(23):15676-84.
2009: Nadiya M Teplyuk; Ying Zhang; Yang Lou; John Hawse; Mohammad Q Hassan; Viktor I Teplyuk; Jitesh Pratap; Mario Galindo; Janet L Stein; Gary S Stein; Jane B Lian; Andre J van Wijnen
The osteogenic transcription factor runx2 controls genes involved in sterol/steroid metabolism, including CYP11A1 in osteoblasts.
Molecular endocrinology (Baltimore, Md.) 2009;23(6):849-61.
2009: Nadiya M Teplyuk; Larisa M Haupt; Ling Ling; Christian Dombrowski; Foong Kin Mun; Saminathan S Nathan; Jane B Lian; Janet L Stein; Gary S Stein; Simon Cool; Andre J van Wijnen
The osteogenic transcription factor Runx2 regulates components of the fibroblast growth factor/proteoglycan signaling axis in osteoblasts.
Journal of cellular biochemistry 2009;107(1):144-54.
2009: Partha Mitra; Prachi N Ghule; Margaretha van der Deen; Ricardo Medina; Rong-Lin Xie; William F Holmes; Xin Ye; Keiichi I Nakayama; J Wade Harper; Janet L Stein; Gary S Stein; Andre J van Wijnen
CDK inhibitors selectively diminish cell cycle controlled activation of the histone H4 gene promoter by p220NPAT and HiNF-P.
Journal of cellular physiology 2009;219(2):438-48.
2009: Sandhya Pande; Syed A Ali; Christopher Dowdy; Sayyed K Zaidi; Kosei Ito; Yoshiaki Ito; Martin Montecino; Jane B Lian; Janet L Stein; Andre J van Wijnen; Gary S Stein
Subnuclear targeting of the Runx3 tumor suppressor and its epigenetic association with mitotic chromosomes.
Journal of cellular physiology 2009;218(3):473-9.
2009: Gary S Stein; Sayyed K Zaidi; Janet L Stein; Jane B Lian; Andre J van Wijnen; Martin Montecino; Daniel W Young; Amjad Javed; Jitesh Pratap; Je-Yong Choi; Syed A Ali; Sandhya Pande; Mohammad Q Hassan
Organization, integration, and assembly of genetic and epigenetic regulatory machinery in nuclear microenvironments: implications for biological control in cancer.
Annals of the New York Academy of Sciences 2009;1155():4-14.
2009: Gary S Stein; Sayyed K Zaidi; Janet L Stein; Jane B Lian; Andre J van Wijnen; Martin Montecino; Daniel W Young; Amjad Javed; Jitesh Pratap; Je-Yong Choi; Syed A Ali; Sandhya Pande; Mohammad Q Hassan
Transcription-factor-mediated epigenetic control of cell fate and lineage commitment.
Biochemistry and cell biology = Biochimie et biologie cellulaire 2009;87(1):1-6.
2009: Yang Lou; Amjad Javed; Sadiq Hussain; Jennifer Colby; Dana Frederick; Jitesh Pratap; Ronglin Xie; Tripti Gaur; Andre J van Wijnen; Stephen N Jones; Gary S Stein; Jane B Lian; Janet L Stein
A Runx2 threshold for the cleidocranial dysplasia phenotype.
Human molecular genetics 2009;18(3):556-68.
2009: Marcela Stuardo; Milka Martinez; Karla Hidalgo; Martin Montecino; Amjad Javed; Jane B Lian; Gary S Stein; Janet L Stein; Soraya E Gutiérrez
Altered chromatin modifications in AML1/RUNX1 breakpoint regions involved in (8;21) translocation.
Journal of cellular physiology 2009;218(2):343-9.
2009: Ying Zhang; Mohammad Q Hassan; Rong-Lin Xie; John Hawse; Thomas C Spelsberg; Martin Montecino; Janet L Stein; Jane B Lian; Andre J van Wijnen; Gary S Stein
Co-stimulation of the bone-related Runx2 P1 promoter in mesenchymal cells by SP1 and ETS transcription factors at polymorphic purine-rich DNA sequences (Y-repeats).
The Journal of biological chemistry 2009;284(5):3125-35.
2009: Amjad Javed; Faiza Afzal; Jong-Sup Bae; Soraya Gutierrez; Kaleem Zaidi; Jitesh Pratap; Andre J van Wijnen; Janet L Stein; Gary S Stein; Jane B Lian
Specific residues of RUNX2 are obligatory for formation of BMP2-induced RUNX2-SMAD complex to promote osteoblast differentiation.
Cells, tissues, organs 2009;189(1-4):133-7.
2009: Mohammad Q Hassan; Sharanjot Saini; Jonathan Gordon; Andre J van Wijnen; Martin Montecino; Janet L Stein; Gary S Stein; Jane B Lian
Molecular switches involving homeodomain proteins, HOXA10 and RUNX2 regulate osteoblastogenesis.
Cells, tissues, organs 2009;189(1-4):122-5.
2008: Rachit Bakshi; Sayyed K Zaidi; Sandhya Pande; Mohammad Q Hassan; Daniel Young; Martin Montecino; Jane B Lian; Andre J van Wijnen; Janet L Stein; Gary S Stein
The leukemogenic t(8;21) fusion protein AML1-ETO controls rRNA genes and associates with nucleolar-organizing regions at mitotic chromosomes.
Journal of cell science 2008;121(Pt 23):3981-90.
2008: Prachi N Ghule; Zbigniew Dominski; Xiao-Cui Yang; William F Marzluff; Klaus A Becker; J Wade Harper; Jane B Lian; Janet L Stein; Andre J van Wijnen; Gary S Stein
Staged assembly of histone gene expression machinery at subnuclear foci in the abbreviated cell cycle of human embryonic stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(44):16964-9.
2008: Ricardo Medina; Timothy Buck; Sayyed K Zaidi; Angela Miele-Chamberland; Jane B Lian; Janet L Stein; Andre J van Wijnen; Gary S Stein
The histone gene cell cycle regulator HiNF-P is a unique zinc finger transcription factor with a novel conserved auxiliary DNA-binding motif.
Biochemistry 2008;47(44):11415-23.
2008: Nadiya M Teplyuk; Mario Galindo; Viktor I Teplyuk; Jitesh Pratap; Daniel Young; David Lapointe; Amjad Javed; Janet L Stein; Jane B Lian; Gary S Stein; Andre J van Wijnen
Runx2 regulates G protein-coupled signaling pathways to control growth of osteoblast progenitors.
The Journal of biological chemistry 2008;283(41):27585-97.
2008: Jitesh Pratap; John J Wixted; Tripti Gaur; Sayyed K Zaidi; Jason Dobson; Karthiga Devi Gokul; Sadiq Hussain; Andre J van Wijnen; Janet L Stein; Gary S Stein; Jane B Lian
Runx2 transcriptional activation of Indian Hedgehog and a downstream bone metastatic pathway in breast cancer cells.
Cancer research 2008;68(19):7795-802.
2008: Ying Zhang; Mohammad Q Hassan; Zhao-Yong Li; Janet L Stein; Jane B Lian; Andre J van Wijnen; Gary S Stein
Intricate gene regulatory networks of helix-loop-helix (HLH) proteins support regulation of bone-tissue related genes during osteoblast differentiation.
Journal of cellular biochemistry 2008;105(2):487-96.
2008: Zhaoyong Li; Mohammad Q Hassan; Stefano Volinia; Andre J van Wijnen; Janet L Stein; Carlo M Croce; Jane B Lian; Gary S Stein
A microRNA signature for a BMP2-induced osteoblast lineage commitment program.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(37):13906-11.
2008: Gary S Stein; Sayyed K Zaidi; Janet L Stein; Jane B Lian; Andre J van Wijnen; Martin Montecino; Daniel Young; Amjad Javed; Jitesh Pratap; Je-Yong Choi; Syed A Ali; Sandhya Pande; Mohammad Q Hassan
Genetic and epigenetic regulation in nuclear microenvironments for biological control in cancer.
Journal of cellular biochemistry 2008;104(6):2016-26.
2008: Syed A Ali; Sayyed K Zaidi; Caroline S Dacwag; Nunciada Salma; Daniel Young; Abdul Rauf Shakoori; Martin Montecino; Jane B Lian; Andre J van Wijnen; Anthony N Imbalzano; Gary S Stein; Janet L Stein
Phenotypic transcription factors epigenetically mediate cell growth control.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(18):6632-7.
2008: Ricardo Medina; Sayyed K Zaidi; Chang-gong liu; Janet L Stein; Andre J van Wijnen; Carlo M Croce; Gary S Stein
MicroRNAs 221 and 222 bypass quiescence and compromise cell survival.
Cancer research 2008;68(8):2773-80.
2008: Amjad Javed; Jong-Sup Bae; Faiza Afzal; Soraya Gutierrez; Jitesh Pratap; Sayyed K Zaidi; Yang Lou; Andre J van Wijnen; Janet L Stein; Gary S Stein; Jane B Lian
Structural coupling of Smad and Runx2 for execution of the BMP2 osteogenic signal.
The Journal of biological chemistry 2008;283(13):8412-22.
2008: Loreto Carvallo; Berta Henríquez; Roberto Paredes; Juan Olate; Sergio A Onate; Andre J van Wijnen; Jane B Lian; Gary S Stein; Janet L Stein; Martin Montecino
1alpha,25-dihydroxy vitamin D3-enhanced expression of the osteocalcin gene involves increased promoter occupancy of basal transcription regulators and gradual recruitment of the 1alpha,25-dihydroxy vitamin D3 receptor-SRC-1 coactivator complex.
Journal of cellular physiology 2008;214(3):740-9.
2008: Shirwin M Pockwinse; Sayyed K Zaidi; Ricardo F Medina; Rachit Bakshi; Krishna P Kota; Syed A Ali; Daniel Young; Jeffery A Nickerson; Amjad Javed; Martin Montecino; Andre J van Wijnen; Jane B Lian; Janet L Stein; Gary S Stein
In situ nuclear organization of regulatory machinery.
Methods in molecular biology (Clifton, N.J.) 2008;455():239-59.
2008: Margaretha van der Deen; Mohammad Q Hassan; Jitesh Pratap; Nadiya M Teplyuk; Daniel Young; Amjad Javed; Sayyed K Zaidi; Jane B Lian; Martin Montecino; Janet L Stein; Gary S Stein; Andre J van Wijnen
Chromatin immunoprecipitation assays: application of ChIP-on-chip for defining dynamic transcriptional mechanisms in bone cells.
Methods in molecular biology (Clifton, N.J.) 2008;455():165-76.
2008: Martin Montecino; Gary S Stein; Janet L Stein; Jane B Lian; Andre J van Wijnen; Loreto Carvallo; Sylvain Marcellini; Fernando Cruzat; Gloria Arriagada
Vitamin D control of gene expression: temporal and spatial parameters for organization of the regulatory machinery.
Critical reviews in eukaryotic gene expression 2008;18(2):163-72.
2007: Sayyed K Zaidi; Sandhya Pande; Jitesh Pratap; Tripti Gaur; Simina Grigoriu; Syed A Ali; Janet L Stein; Jane B Lian; Andre J van Wijnen; Gary S Stein
Runx2 deficiency and defective subnuclear targeting bypass senescence to promote immortalization and tumorigenic potential.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(50):19861-6.
2007: Ricardo Medina; Margaretha van der Deen; Angela Miele-Chamberland; Rong-Lin Xie; Andre J van Wijnen; Janet L Stein; Gary S Stein
The HiNF-P/p220NPAT cell cycle signaling pathway controls nonhistone target genes.
Cancer research 2007;67(21):10334-42.
2007: Rong-Lin Xie; Lijun Liu; Partha Mitra; Janet L Stein; Andre J van Wijnen; Gary S Stein
Transcriptional activation of the histone nuclear factor P (HiNF-P) gene by HiNF-P and its cyclin E/CDK2 responsive co-factor p220NPAT defines a novel autoregulatory loop at the G1/S phase transition.
Gene 2007;402(1-2):94-102.
2007: Mario Galindo; Rachel A Kahler; Nadiya M Teplyuk; Janet L Stein; Jane B Lian; Gary S Stein; Jennifer J Westendorf; Andre J van Wijnen
Cell cycle related modulations in Runx2 protein levels are independent of lymphocyte enhancer-binding factor 1 (Lef1) in proliferating osteoblasts.
Journal of molecular histology 2007;38(5):501-6.
2007: Prachi N Ghule; Klaus A Becker; J Wade Harper; Jane B Lian; Janet L Stein; Andre J van Wijnen; Gary S Stein
Cell cycle dependent phosphorylation and subnuclear organization of the histone gene regulator p220(NPAT) in human embryonic stem cells.
Journal of cellular physiology 2007;213(1):9-17.
2007: Angela Miele; Ricardo Medina; Andre J van Wijnen; Gary S Stein; Janet L Stein
The interactome of the histone gene regulatory factor HiNF-P suggests novel cell cycle related roles in transcriptional control and RNA processing.
Journal of cellular biochemistry 2007;102(1):136-48.
2007: Martin Montecino; Janet L Stein; Gary S Stein; Jane B Lian; Andre J van Wijnen; Fernando Cruzat; Soraya Gutiérrez; Juan Olate; Sylvain Marcellini; José L Gutiérrez
Nucleosome organization and targeting of SWI/SNF chromatin-remodeling complexes: contributions of the DNA sequence.
Biochemistry and cell biology = Biochimie et biologie cellulaire 2007;85(4):419-25.
2007: Sayyed K Zaidi; Daniel Young; Amjad Javed; Jitesh Pratap; Martin Montecino; Andre J van Wijnen; Jane B Lian; Janet L Stein; Gary S Stein
Nuclear microenvironments in biological control and cancer.
Nature reviews. Cancer 2007;7(6):454-63.
2007: Mohammad Q Hassan; Rahul Tare; Suk Hee Lee; Matthew Mandeville; Brian Weiner; Martin Montecino; Andre J van Wijnen; Janet L Stein; Gary S Stein; Jane B Lian
HOXA10 controls osteoblastogenesis by directly activating bone regulatory and phenotypic genes.
Molecular and cellular biology 2007;27(9):3337-52.
2007: Partha Mitra; Ronglin Xie; J Wade Harper; Janet L Stein; Gary S Stein; Andre J van Wijnen
HiNF-P is a bifunctional regulator of cell cycle controlled histone H4 gene transcription.
Journal of cellular biochemistry 2007;101(1):181-91.
2007: Martin Montecino; Gary S Stein; Fernando Cruzat; Sylvain Marcellini; Janet L Stein; Jane B Lian; Andre J van Wijnen; Gloria Arriagada
An architectural perspective of vitamin D responsiveness.
Archives of biochemistry and biophysics 2007;460(2):293-9.
2007: Arun Rajgopal; Daniel Young; Khawaja A Mujeeb; Janet L Stein; Jane B Lian; Andre J van Wijnen; Gary S Stein
Mitotic control of RUNX2 phosphorylation by both CDK1/cyclin B kinase and PP1/PP2A phosphatase in osteoblastic cells.
Journal of cellular biochemistry 2007;100(6):1509-17.
2007: José Gutiérrez; Roberto Paredes; Fernando Cruzat; David A Hill; Andre J van Wijnen; Jane B Lian; Gary S Stein; Janet L Stein; Anthony N Imbalzano; Martin Montecino
Chromatin remodeling by SWI/SNF results in nucleosome mobilization to preferential positions in the rat osteocalcin gene promoter.
The Journal of biological chemistry 2007;282(13):9445-57.
2007: Gloria Arriagada; Roberto Paredes; Juan Olate; Andre J van Wijnen; Jane B Lian; Gary S Stein; Janet L Stein; Sergio A Onate; Martin Montecino
Phosphorylation at serine 208 of the 1alpha,25-dihydroxy Vitamin D3 receptor modulates the interaction with transcriptional coactivators.
The Journal of steroid biochemistry and molecular biology 2007;103(3-5):425-9.
2007: Loreto Carvallo; Berta Henriquez; Juan Olate; Andre J van Wijnen; Jane B Lian; Gary S Stein; Sergio A Onate; Janet L Stein; Martin Montecino
The 1alpha,25-dihydroxy Vitamin D3 receptor preferentially recruits the coactivator SRC-1 during up-regulation of the osteocalcin gene.
The Journal of steroid biochemistry and molecular biology 2007;103(3-5):420-4.
2007: Daniel Young; Mohammad Q Hassan; Xiao-Qing Yang; Mario Galindo; Amjad Javed; Sayyed K Zaidi; Paul Furcinitti; David Lapointe; Martin Montecino; Jane B Lian; Janet L Stein; Andre J van Wijnen; Gary S Stein
Mitotic retention of gene expression patterns by the cell fate-determining transcription factor Runx2.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(9):3189-94.
2007: Klaus A Becker; Janet L Stein; Jane B Lian; Andre J van Wijnen; Gary S Stein
Establishment of histone gene regulation and cell cycle checkpoint control in human embryonic stem cells.
Journal of cellular physiology 2007;210(2):517-26.
2007: Jong-Sup Bae; Soraya Gutierrez; Radhika Narla; Jitesh Pratap; Rajitha Devados; Andre J van Wijnen; Janet L Stein; Gary S Stein; Jane B Lian; Amjad Javed
Reconstitution of Runx2/Cbfa1-null cells identifies a requirement for BMP2 signaling through a Runx2 functional domain during osteoblast differentiation.
Journal of cellular biochemistry 2007;100(2):434-49.
2007: Daniel Young; Mohammad Q Hassan; Jitesh Pratap; Mario Galindo; Sayyed K Zaidi; Suk-hee Lee; Xiaoqing Yang; Ronglin Xie; Amjad Javed; Jean M Underwood; Paul Furcinitti; Anthony N Imbalzano; Sheldon Penman; Jeffrey A Nickerson; Martin Montecino; Jane B Lian; Janet L Stein; Andre J van Wijnen; Gary S Stein
Mitotic occupancy and lineage-specific transcriptional control of rRNA genes by Runx2.
Nature 2007;445(7126):442-6.
2007: Gary S Stein; Jane B Lian; Andre J van Wijnen; Janet L Stein; Amjad Javed; Martin Montecino; Je-Yong Choi; Diana Vradii; Sayyed K Zaidi; Jitesh Pratap; Daniel Young
Organization of transcriptional regulatory machinery in nuclear microenvironments: implications for biological control and cancer.
Advances in enzyme regulation 2007;47():242-50.
2006: Mohammad Q Hassan; Rahul S Tare; Suk Hee Lee; Matthew Mandeville; Maria I Morasso; Amjad Javed; Andre J van Wijnen; Janet L Stein; Gary S Stein; Jane B Lian
BMP2 commitment to the osteogenic lineage involves activation of Runx2 by DLX3 and a homeodomain transcriptional network.
The Journal of biological chemistry 2006;281(52):40515-26.
2006: Ricardo Medina; Andre J van Wijnen; Gary S Stein; Janet L Stein
The histone gene transcription factor HiNF-P stabilizes its cell cycle regulatory co-activator p220NPAT.
Biochemistry 2006;45(51):15915-20.
2006: Jitesh Pratap; Jane B Lian; Amjad Javed; George L Barnes; Andre J van Wijnen; Janet L Stein; Gary S Stein
Regulatory roles of Runx2 in metastatic tumor and cancer cell interactions with bone.
Cancer metastasis reviews 2006;25(4):589-600.
2006: Gary S Stein; Andre J van Wijnen; Janet L Stein; Jane B Lian; Martin Montecino; Sayyed K Zaidi; Corey D Braastad
An architectural perspective of cell-cycle control at the G1/S phase cell-cycle transition.
Journal of cellular physiology 2006;209(3):706-10.
2006: Sayyed K Zaidi; Amjad Javed; Jitesh Pratap; Tania M Schroeder; Jennifer J Westendorf; Jane B Lian; Andre J van Wijnen; Gary S Stein; Janet L Stein
Alterations in intranuclear localization of Runx2 affect biological activity.
Journal of cellular physiology 2006;209(3):935-42.
2006: Klaus A Becker; Prachi N Ghule; Jaclyn A Therrien; Jane B Lian; Janet L Stein; Andre J van Wijnen; Gary S Stein
Self-renewal of human embryonic stem cells is supported by a shortened G1 cell cycle phase.
Journal of cellular physiology 2006;209(3):883-93.
2006: Soraya Bravo; Roberto Paredes; Pamela Izaurieta; Jane B Lian; Janet L Stein; Gary S Stein; María Victoria Hinrichs; Juan Olate; Luis G Aguayo; Martin Montecino
The classic receptor for 1alpha,25-dihydroxy vitamin D3 is required for non-genomic actions of 1alpha,25-dihydroxy vitamin D3 in osteosarcoma cells.
Journal of cellular biochemistry 2006;99(4):995-1000.
2006: alejandro villagra; Fernando Cruzat; Loreto Carvallo; Roberto Paredes; Juan Olate; Andre J van Wijnen; Gary S Stein; Jane B Lian; Janet L Stein; Anthony N Imbalzano; Martin Montecino
Chromatin remodeling and transcriptional activity of the bone-specific osteocalcin gene require CCAAT/enhancer-binding protein beta-dependent recruitment of SWI/SNF activity.
The Journal of biological chemistry 2006;281(32):22695-706.
2006: Tripti Gaur; Lillian Rich; Christopher J Lengner; Sadiq Hussain; Brune Trevant; David Ayers; Janet L Stein; Peter V N Bodine; Barry S Komm; Gary S Stein; Jane B Lian
Secreted frizzled related protein 1 regulates Wnt signaling for BMP2 induced chondrocyte differentiation.
Journal of cellular physiology 2006;208(1):87-96.
2006: Jane B Lian; Gary S Stein; Amjad Javed; Andre J van Wijnen; Janet L Stein; Martin Montecino; Mohammad Q Hassan; Tripti Gaur; Christopher J Lengner; Daniel Young
Networks and hubs for the transcriptional control of osteoblastogenesis.
Reviews in endocrine & metabolic disorders 2006;7(1-2):1-16.
2006: Shirwin M Pockwinse; Arun Rajgopal; Daniel Young; Khwaja A Mujeeb; Jeffrey A Nickerson; Amjad Javed; Sambra Redick; Jane B Lian; Andre J van Wijnen; Janet L Stein; Gary S Stein; Stephen J Doxsey
Microtubule-dependent nuclear-cytoplasmic shuttling of Runx2.
Journal of cellular physiology 2006;206(2):354-62.
2006: Diana Vradii; Stefan Wagner; Diem N Doan; Jeffrey A Nickerson; Martin Montecino; Jane B Lian; Janet L Stein; Andre J van Wijnen; Anthony N Imbalzano; Gary S Stein
Brg1, the ATPase subunit of the SWI/SNF chromatin remodeling complex, is required for myeloid differentiation to granulocytes.
Journal of cellular physiology 2006;206(1):112-8.
2005: William F Holmes; Corey D Braastad; Partha Mitra; Cornelia Hampe; Detlef Doenecke; Werner Albig; Janet L Stein; Andre J van Wijnen; Gary S Stein
Coordinate control and selective expression of the full complement of replication-dependent histone H4 genes in normal and cancer cells.
The Journal of biological chemistry 2005;280(45):37400-7.
2005: Xiangen Li; Diana Vradii; Soraya Gutierrez; Jane B Lian; Andre J van Wijnen; Janet L Stein; Gary S Stein; Amjad Javed
Subnuclear targeting of Runx1 is required for synergistic activation of the myeloid specific M-CSF receptor promoter by PU.1.
Journal of cellular biochemistry 2005;96(4):795-809.
2005: Jitesh Pratap; Amjad Javed; Lucia R Languino; Andre J van Wijnen; Janet L Stein; Gary S Stein; Jane B Lian
The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion.
Molecular and cellular biology 2005;25(19):8581-91.
2005: Tripti Gaur; Christopher J Lengner; Hayk Hovhannisyan; Ramesh A Bhat; Peter V N Bodine; Barry S Komm; Amjad Javed; Andre J van Wijnen; Janet L Stein; Gary S Stein; Jane B Lian
Canonical WNT signaling promotes osteogenesis by directly stimulating Runx2 gene expression.
The Journal of biological chemistry 2005;280(39):33132-40.
2005: Laura H Saltman; Amjad Javed; John Ribadeneyra; Sadiq Hussain; Daniel Young; Philip Osdoby; Alla Amcheslavsky; Andre J van Wijnen; Janet L Stein; Gary S Stein; Jane B Lian; Zvi Bar-Shavit
Organization of transcriptional regulatory machinery in osteoclast nuclei: compartmentalization of Runx1.
Journal of cellular physiology 2005;204(3):871-80.
2005: Angela Miele; Corey D Braastad; William F Holmes; Partha Mitra; Ricardo Medina; Ronglin Xie; Sayyed K Zaidi; Xin Ye; Yue Wei; J Wade Harper; Andre J van Wijnen; Janet L Stein; Gary S Stein
HiNF-P directly links the cyclin E/CDK2/p220NPAT pathway to histone H4 gene regulation at the G1/S phase cell cycle transition.
Molecular and cellular biology 2005;25(14):6140-53.
2005: Faiza Afzal; Jitesh Pratap; Kosei Ito; Yoshiaki Ito; Janet L Stein; Andre J van Wijnen; Gary S Stein; Jane B Lian; Amjad Javed
Smad function and intranuclear targeting share a Runx2 motif required for osteogenic lineage induction and BMP2 responsive transcription.
Journal of cellular physiology 2005;204(1):63-72.
2005: Mario Galindo; Jitesh Pratap; Daniel Young; Hayk Hovhannisyan; Hee-Jeong Im; Je-Yong Choi; Jane B Lian; Janet L Stein; Gary S Stein; Andre J van Wijnen
The bone-specific expression of Runx2 oscillates during the cell cycle to support a G1-related antiproliferative function in osteoblasts.
The Journal of biological chemistry 2005;280(21):20274-85.
2005: Diana Vradii; Sayyed K Zaidi; Jane B Lian; Andre J van Wijnen; Janet L Stein; Gary S Stein
Point mutation in AML1 disrupts subnuclear targeting, prevents myeloid differentiation, and effects a transformation-like phenotype.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(20):7174-9.
2005: Christopher J Lengner; Mohammad Q Hassan; Ryan W Serra; Christoph Lepper; Andre J van Wijnen; Janet L Stein; Jane B Lian; Gary S Stein
Nkx3.2-mediated repression of Runx2 promotes chondrogenic differentiation.
The Journal of biological chemistry 2005;280(16):15872-9.
2005: Daniel Young; Jitesh Pratap; Amjad Javed; Brian Weiner; Yasuyuki Ohkawa; Andre J van Wijnen; Martin Montecino; Gary S Stein; Janet L Stein; Anthony N Imbalzano; Jane B Lian
SWI/SNF chromatin remodeling complex is obligatory for BMP2-induced, Runx2-dependent skeletal gene expression that controls osteoblast differentiation.
Journal of cellular biochemistry 2005;94(4):720-30.
2005: Sayyed K Zaidi; Daniel Young; Je-Yong Choi; Jitesh Pratap; Amjad Javed; Martin Montecino; Janet L Stein; Andre J van Wijnen; Jane B Lian; Gary S Stein
The dynamic organization of gene-regulatory machinery in nuclear microenvironments.
EMBO reports 2005;6(2):128-33.
2005: Amjad Javed; George L Barnes; Jitesh Pratap; Tomasz Antkowiak; Louis C Gerstenfeld; Andre J van Wijnen; Janet L Stein; Jane B Lian; Gary S Stein
Impaired intranuclear trafficking of Runx2 (AML3/CBFA1) transcription factors in breast cancer cells inhibits osteolysis in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(5):1454-9.
2005: Gary S Stein; Jane B Lian; Janet L Stein; Andre J van Wijnen; Amjad Javed; Martin Montecino; Sayyed K Zaidi; Daniel Young; Je-Yong Choi; Jitesh Pratap
Combinatorial organization of the transcriptional regulatory machinery in biological control and cancer.
Advances in enzyme regulation 2005;45():136-54.
2004: Corey D Braastad; Hayk Hovhannisyan; Andre J van Wijnen; Janet L Stein; Gary S Stein
Functional characterization of a human histone gene cluster duplication.
Gene 2004;342(1):35-40.
2004: Soraya Gutierrez; Jilin Liu; Amjad Javed; Martin Montecino; Gary S Stein; Jane B Lian; Janet L Stein
The vitamin D response element in the distal osteocalcin promoter contributes to chromatin organization of the proximal regulatory domain.
The Journal of biological chemistry 2004;279(42):43581-8.
2004: Sayyed K Zaidi; Daniel Young; Je-Yong Choi; Jitesh Pratap; Amjad Javed; Martin Montecino; Janet L Stein; Jane B Lian; Andre J van Wijnen; Gary S Stein
Intranuclear trafficking: organization and assembly of regulatory machinery for combinatorial biological control.
The Journal of biological chemistry 2004;279(42):43363-6.
2004: Mohammad Q Hassan; Amjad Javed; Maria I Morasso; Jeremy Karlin; Martin Montecino; Andre J van Wijnen; Gary S Stein; Janet L Stein; Jane B Lian
Dlx3 transcriptional regulation of osteoblast differentiation: temporal recruitment of Msx2, Dlx3, and Dlx5 homeodomain proteins to chromatin of the osteocalcin gene.
Molecular and cellular biology 2004;24(20):9248-61.
2004: Roberto Paredes; Gloria Arriagada; Fernando Cruzat; alejandro villagra; Juan Olate; Kaleem Zaidi; Andre J van Wijnen; Jane B Lian; Gary S Stein; Janet L Stein; Martin Montecino
Bone-specific transcription factor Runx2 interacts with the 1alpha,25-dihydroxyvitamin D3 receptor to up-regulate rat osteocalcin gene expression in osteoblastic cells.
Molecular and cellular biology 2004;24(20):8847-61.
2004: Daniel Young; Sayyed K Zaidi; Paul Furcinitti; Amjad Javed; Andre J van Wijnen; Janet L Stein; Jane B Lian; Gary S Stein
Quantitative signature for architectural organization of regulatory factors using intranuclear informatics.
Journal of cell science 2004;117(Pt 21):4889-96.
2004: Christopher J Lengner; Christoph Lepper; Andre J van Wijnen; Janet L Stein; Gary S Stein; Jane B Lian
Primary mouse embryonic fibroblasts: a model of mesenchymal cartilage formation.
Journal of cellular physiology 2004;200(3):327-33.
2004: Gary S Stein; Jane B Lian; Andre J van Wijnen; Janet L Stein; Martin Montecino; Amjad Javed; Sayyed K Zaidi; Daniel Young; Je-Yong Choi; Shirwin M Pockwinse
Runx2 control of organization, assembly and activity of the regulatory machinery for skeletal gene expression.
Oncogene 2004;23(24):4315-29.
2004: Sayyed K Zaidi; Andrew J Sullivan; Ricardo Medina; Yoshiaki Ito; Andre J van Wijnen; Janet L Stein; Jane B Lian; Gary S Stein
Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription.
The EMBO journal 2004;23(4):790-9.
2004: Gary S Stein; Jane B Lian; Andre J van Wijnen; Janet L Stein; Amjad Javed; Martin Montecino; Sayyed K Zaidi; Daniel Young; Je-Yong Choi; Soraya Gutierrez; Shirwin M Pockwinse
Nuclear microenvironments support assembly and organization of the transcriptional regulatory machinery for cell proliferation and differentiation.
Journal of cellular biochemistry 2004;91(2):287-302.
2004: Amjad Javed; Sayyed K Zaidi; Soraya Gutierrez; Christopher J Lengner; Kimberly S Harrington; Hayk Hovhannisyan; Brian C Cho; Jitesh Pratap; Shirwin M Pockwinse; Martin Montecino; Andre J van Wijnen; Jane B Lian; Janet L Stein; Gary S Stein
Protein-deoxyribonucleic acid interactions linked to gene expression: ligation-mediated polymerase chain reaction.
Methods in molecular biology (Clifton, N.J.) 2004;285():63-7.
2004: Amjad Javed; Sayyed K Zaidi; Soraya Gutierrez; Christopher J Lengner; Kimberly S Harrington; Hayk Hovhannisyan; Brian C Cho; Jitesh Pratap; Shirwin M Pockwinse; Martin Montecino; Andre J van Wijnen; Jane B Lian; Janet L Stein; Gary S Stein
Protein-deoxyribonucleic acid interactions linked to gene expression: DNase I digestion.
Methods in molecular biology (Clifton, N.J.) 2004;285():57-62.
2004: Amjad Javed; Sayyed K Zaidi; Soraya Gutierrez; Christopher J Lengner; Kimberly S Harrington; Hayk Hovhannisyan; Brian C Cho; Jitesh Pratap; Shirwin M Pockwinse; Martin Montecino; Andre J van Wijnen; Jane B Lian; Janet L Stein; Gary S Stein
Protein-deoxyribonucleic acid interactions linked to gene expression: electrophoretic mobility shift assay.
Methods in molecular biology (Clifton, N.J.) 2004;285():45-55.
2004: Amjad Javed; Sayyed K Zaidi; Soraya Gutierrez; Christopher J Lengner; Kimberly S Harrington; Hayk Hovhannisyan; Brian C Cho; Jitesh Pratap; Shirwin M Pockwinse; Martin Montecino; Andre J van Wijnen; Jane B Lian; Janet L Stein; Gary S Stein
Chromatin immunoprecipitation.
Methods in molecular biology (Clifton, N.J.) 2004;285():41-4.
2004: Amjad Javed; Sayyed K Zaidi; Soraya Gutierrez; Christopher J Lengner; Kimberly S Harrington; Hayk Hovhannisyan; Brian C Cho; Jitesh Pratap; Shirwin M Pockwinse; Martin Montecino; Andre J van Wijnen; Jane B Lian; Janet L Stein; Gary S Stein
Analysis of in vivo gene expression using epitope-tagged proteins.
Methods in molecular biology (Clifton, N.J.) 2004;285():37-40.
2004: Amjad Javed; Sayyed K Zaidi; Soraya Gutierrez; Christopher J Lengner; Kimberly S Harrington; Hayk Hovhannisyan; Brian C Cho; Jitesh Pratap; Shirwin M Pockwinse; Martin Montecino; Andre J van Wijnen; Jane B Lian; Janet L Stein; Gary S Stein
Immunofluorescence analysis using epitope-tagged proteins: in vitro system.
Methods in molecular biology (Clifton, N.J.) 2004;285():33-6.
2004: Amjad Javed; Sayyed K Zaidi; Soraya Gutierrez; Christopher J Lengner; Kimberly S Harrington; Hayk Hovhannisyan; Brian C Cho; Jitesh Pratap; Shirwin M Pockwinse; Martin Montecino; Andre J van Wijnen; Jane B Lian; Janet L Stein; Gary S Stein
In situ immunofluorescence analysis: analyzing RNA synthesis by 5-bromouridine-5'-triphosphate labeling.
Methods in molecular biology (Clifton, N.J.) 2004;285():29-31.
2004: Amjad Javed; Sayyed K Zaidi; Soraya Gutierrez; Christopher J Lengner; Kimberly S Harrington; Hayk Hovhannisyan; Brian C Cho; Jitesh Pratap; Shirwin M Pockwinse; Martin Montecino; Andre J van Wijnen; Jane B Lian; Janet L Stein; Gary S Stein
In situ immunofluorescence analysis: immunofluorescence microscopy.
Methods in molecular biology (Clifton, N.J.) 2004;285():23-8.
2004: Gary S Stein; Janet L Stein; Jane B Lian; Andre J van Wijnen; Martin Montecino; Amjad Javed; Sayyed K Zaidi; Daniel Young; Je-Yong Choi; Shirwin M Pockwinse
Nuclear microenvironments: an architectural platform for the convergence and integration of transcriptional regulatory signals.
European journal of histochemistry : EJH 2004;48(1):65-76.
2004: Jane B Lian; Amjad Javed; Sayyed K Zaidi; Christopher J Lengner; Martin Montecino; Andre J van Wijnen; Janet L Stein; Gary S Stein
Regulatory controls for osteoblast growth and differentiation: role of Runx/Cbfa/AML factors.
Critical reviews in eukaryotic gene expression 2004;14(1-2):1-41.
2003: Sayyed K Zaidi; Daniel Young; Shirwin M Pockwinse; Amjad Javed; Jane B Lian; Janet L Stein; Andre J van Wijnen; Gary S Stein
Mitotic partitioning and selective reorganization of tissue-specific transcription factors in progeny cells.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(25):14852-7.
2003: Partha Mitra; Rong-Lin Xie; Ricardo Medina; Hayk Hovhannisyan; Sayyed K Zaidi; Yue Wei; J Wade Harper; Janet L Stein; Andre J van Wijnen; Gary S Stein
Identification of HiNF-P, a key activator of cell cycle-controlled histone H4 genes at the onset of S phase.
Molecular and cellular biology 2003;23(22):8110-23.
2003: Gary S Stein; Sayyed K Zaidi; Corey D Braastad; Martin Montecino; Andre J van Wijnen; Je-Yong Choi; Janet L Stein; Jane B Lian; Amjad Javed
Functional architecture of the nucleus: organizing the regulatory machinery for gene expression, replication and repair.
Trends in cell biology 2003;13(11):584-92.
2003: Jitesh Pratap; Mario Galindo; Sayyed K Zaidi; Diana Vradii; Bheem Bhat; John A Robinson; Je-Yong Choi; Toshisha Komori; Janet L Stein; Jane B Lian; Gary S Stein; Andre J van Wijnen
Cell growth regulatory role of Runx2 during proliferative expansion of preosteoblasts.
Cancer research 2003;63(17):5357-62.
2003: Sunita Gupta; Mai X Luong; Sylvia A Bleuming; Angela Miele; Michael Luong; Daniel Young; Erik S Knudsen; Andre J van Wijnen; Janet L Stein; Gary S Stein
Tumor suppressor pRB functions as a co-repressor of the CCAAT displacement protein (CDP/cut) to regulate cell cycle controlled histone H4 transcription.
Journal of cellular physiology 2003;196(3):541-56.
2003: Jane B Lian; Eva Balint; Amjad Javed; Hicham Drissi; Regan Vitti; Edward J Quinlan; Lina Zhang; Andre J van Wijnen; Janet L Stein; Nancy Speck; Gary S Stein
Runx1/AML1 hematopoietic transcription factor contributes to skeletal development in vivo.
Journal of cellular physiology 2003;196(2):301-11.
2003: Rong-Lin Xie; Sunita Gupta; Angela Miele; Dov Shiffman; Janet L Stein; Gary S Stein; Andre J van Wijnen
The tumor suppressor interferon regulatory factor 1 interferes with SP1 activation to repress the human CDK2 promoter.
The Journal of biological chemistry 2003;278(29):26589-96.
2003: Eva Balint; David Lapointe; Hicham Drissi; Caroline van der Meijden; Daniel Young; Andre J van Wijnen; Janet L Stein; Gary S Stein; Jane B Lian
Phenotype discovery by gene expression profiling: mapping of biological processes linked to BMP-2-mediated osteoblast differentiation.
Journal of cellular biochemistry 2003;89(2):401-26.
2003: Jose Sierra; alejandro villagra; Roberto Paredes; Fernando Cruzat; Soraya Gutierrez; Amjad Javed; Gloria Arriagada; Juan Olate; Maria Imschenetzky; Andre J van Wijnen; Jane B Lian; Gary S Stein; Janet L Stein; Martin Montecino
Regulation of the bone-specific osteocalcin gene by p300 requires Runx2/Cbfa1 and the vitamin D3 receptor but not p300 intrinsic histone acetyltransferase activity.
Molecular and cellular biology 2003;23(9):3339-51.
2003: Jiali Shen; Hayk Hovhannisyan; Jane B Lian; Martin Montecino; Gary S Stein; Janet L Stein; Andre J van Wijnen
Transcriptional induction of the osteocalcin gene during osteoblast differentiation involves acetylation of histones h3 and h4.
Molecular endocrinology (Baltimore, Md.) 2003;17(4):743-56.
2003: Gary S Stein; Jane B Lian; Janet L Stein; Andre J van Wijnen; Martin Montecino; Jitesh Pratap; Je Choi; Sayyed K Zaidi; Amjad Javed; Soraya Gutierrez; Kimberly Harrington; Jiali Shen; Daniel Young
Intranuclear organization of RUNX transcriptional regulatory machinery in biological control of skeletogenesis and cancer.
Blood cells, molecules & diseases 2003;30(2):170-6.
2003: Hayk Hovhannisyan; Brian Cho; Partha Mitra; Martin Montecino; Gary S Stein; Andre J van Wijnen; Janet L Stein
Maintenance of open chromatin and selective genomic occupancy at the cell cycle-regulated histone H4 promoter during differentiation of HL-60 promyelocytic leukemia cells.
Molecular and cellular biology 2003;23(4):1460-9.
2003: Gary S Stein; Jane B Lian; Janet L Stein; André J van Wijnen; Martin Montecino; Amjad Javed; Jitesh Pratap; Je Choi; Sayyed K Zaidi; Soraya Gutierrez; Kimberly Harrington; Jiali Shen; Daniel Young
Intranuclear trafficking of transcription factors: Requirements for vitamin D-mediated biological control of gene expression.
Journal of cellular biochemistry 2003;88(2):340-55.
2003: Gary S Stein; Jane B Lian; Martin Montecino; Janet L Stein; Andre J van Wijnen; Amjad Javed; Jitesh Pratap; Je Choi; Sayyed K Zaidi; Soraya Gutierrez; Kimberly Harrington; Jiali Shen; Daniel Young; Shirwin M Pockwinse
Nuclear microenvironments support physiological control of gene expression.
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology 2003;11(5):527-36.
2003: Gary S Stein; Jane B Lian; Janet L Stein; Andre J van Wijnen; Je Y Choi; Jitesh Pratap; Sayyed K Zaidi
Temporal and spatial parameters of skeletal gene expression: targeting RUNX factors and their coregulatory proteins to subnuclear domains.
Connective tissue research 2003;44 Suppl 1():149-53.
2003: Jane B Lian; Janet L Stein; Gary S Stein; Andre J van Wijnen; Martin Montecino; Amjad Javed; Soraya Gutierrez; Jiali Shen; Sayyed K Zaidi; Hicham Drissi
Runx2/Cbfa1 functions: diverse regulation of gene transcription by chromatin remodeling and co-regulatory protein interactions.
Connective tissue research 2003;44 Suppl 1():141-8.
2002: Karina Barseguian; Bart Lutterbach; Scott W Hiebert; Jeffrey A Nickerson; Jane B Lian; Janet L Stein; Andre J van Wijnen; Gary S Stein
Multiple subnuclear targeting signals of the leukemia-related AML1/ETO and ETO repressor proteins.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(24):15434-9.
2002: Kimberly S Harrington; Amjad Javed; Hicham Drissi; Sandra McNeil; Jane B Lian; Janet L Stein; Andre J van Wijnen; Yu-Li Wang; Gary S Stein
Transcription factors RUNX1/AML1 and RUNX2/Cbfa1 dynamically associate with stationary subnuclear domains.
Journal of cell science 2002;115(Pt 21):4167-76.
2002: Sayyed K Zaidi; Andrew J Sullivan; Andre J van Wijnen; Janet L Stein; Gary S Stein; Jane B Lian
Integration of Runx and Smad regulatory signals at transcriptionally active subnuclear sites.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(12):8048-53.
2002: Jiali Shen; Martin Montecino; Jane B Lian; Gary S Stein; Andre J van Wijnen; Janet L Stein
Histone acetylation in vivo at the osteocalcin locus is functionally linked to vitamin D-dependent, bone tissue-specific transcription.
The Journal of biological chemistry 2002;277(23):20284-92.
2002: Christopher J Lengner; Hicham Drissi; Je-Yong Choi; Andre J van Wijnen; Janet L Stein; Gary S Stein; Jane B Lian
Activation of the bone-related Runx2/Cbfa1 promoter in mesenchymal condensations and developing chondrocytes of the axial skeleton.
Mechanisms of development 2002;114(1-2):167-70.
2002: Caroline M van der Meijden; David S Lapointe; Mai X Luong; Daniel Peric-Hupkes; Brian Cho; Janet L Stein; Andre J van Wijnen; Gary S Stein
Gene profiling of cell cycle progression through S-phase reveals sequential expression of genes required for DNA replication and nucleosome assembly.
Cancer research 2002;62(11):3233-43.
2002: Rong-Lin Xie; Andre J van Wijnen; Caroline M van der Meijden; Janet L Stein; Gary S Stein
Forced expression of the interferon regulatory factor 2 oncoprotein causes polyploidy and cell death in FDC-P1 myeloid hematopoietic progenitor cells.
Cancer research 2002;62(9):2510-5.
2002: Hicham Drissi; Arlyssa Pouliot; Christian Koolloos; Janet L Stein; Jane B Lian; Gary S Stein; Andre J van Wijnen
1,25-(OH)2-vitamin D3 suppresses the bone-related Runx2/Cbfa1 gene promoter.
Experimental cell research 2002;274(2):323-33.
2002: Mai X Luong; Caroline M van der Meijden; DongXia Xing; Ruth Hesselton; Edwin S Monuki; Stephen N Jones; Jane B Lian; Janet L Stein; Gary S Stein; Ellis J Neufeld; Andre J van Wijnen
Genetic ablation of the CDP/Cux protein C terminus results in hair cycle defects and reduced male fertility.
Molecular and cellular biology 2002;22(5):1424-37.
2002: Soraya Gutierrez; Amjad Javed; Daniel K Tennant; Monique van Rees; Martin Montecino; Gary S Stein; Janet L Stein; Jane B Lian
CCAAT/enhancer-binding proteins (C/EBP) beta and delta activate osteocalcin gene transcription and synergize with Runx2 at the C/EBP element to regulate bone-specific expression.
The Journal of biological chemistry 2002;277(2):1316-23.
2002: Hicham Drissi; Arlyssa Pouliot; Janet L Stein; Andre J van Wijnen; Gary S Stein; Jane B Lian
Identification of novel protein/DNA interactions within the promoter of the bone-related transcription factor Runx2/Cbfa1.
Journal of cellular biochemistry 2002;86(2):403-12.
2001: P Mitra; P S Vaughan; Janet L Stein; Gary S Stein; Andre J van Wijnen
Purification and functional analysis of a novel leucine-zipper/nucleotide-fold protein, BZAP45, stimulating cell cycle regulated histone H4 gene transcription.
Biochemistry 2001;40(35):10693-9.
2001: Sayyed K Zaidi; Amjad Javed; Je-Yong Choi; Andre J van Wijnen; Janet L Stein; Jane B Lian; Gary S Stein
A specific targeting signal directs Runx2/Cbfa1 to subnuclear domains and contributes to transactivation of the osteocalcin gene.
Journal of cell science 2001;114(Pt 17):3093-102.
2001: C Banerjee; Amjad Javed; Je-Yong Choi; J Green; V Rosen; Andre J van Wijnen; Janet L Stein; Jane B Lian; Gary S Stein
Differential regulation of the two principal Runx2/Cbfa1 n-terminal isoforms in response to bone morphogenetic protein-2 during development of the osteoblast phenotype.
Endocrinology 2001;142(9):4026-39.
2001: Je-Yong Choi; Jitesh Pratap; Amjad Javed; Sayyed K Zaidi; L Xing; Eva Balint; S Dalamangas; B Boyce; Andre J van Wijnen; Jane B Lian; Janet L Stein; Stephen N Jones; Gary S Stein
Subnuclear targeting of Runx/Cbfa/AML factors is essential for tissue-specific differentiation during embryonic development.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(15):8650-5.
2001: R Xie; Andre J van Wijnen; Caroline M van der Meijden; Mai X Luong; Janet L Stein; Gary S Stein
The cell cycle control element of histone H4 gene transcription is maximally responsive to interferon regulatory factor pairs IRF-1/IRF-3 and IRF-1/IRF-7.
The Journal of biological chemistry 2001;276(21):18624-32.
2001: Amjad Javed; George L Barnes; B O Jasanya; Janet L Stein; Louis C Gerstenfeld; Jane B Lian; Gary S Stein
runt homology domain transcription factors (Runx, Cbfa, and AML) mediate repression of the bone sialoprotein promoter: evidence for promoter context-dependent activity of Cbfa proteins.
Molecular and cellular biology 2001;21(8):2891-905.
2001: Lindsay S Shopland; Meg Byron; Janet L Stein; Jane B Lian; Gary S Stein; Jeanne B Lawrence
Replication-dependent histone gene expression is related to Cajal body (CB) association but does not require sustained CB contact.
Molecular biology of the cell 2001;12(3):565-76.
2000: A Staal; J M Enserink; Janet L Stein; Gary S Stein; Andre J van Wijnen
Molecular characterization of celtix-1, a bromodomain protein interacting with the transcription factor interferon regulatory factor 2.
Journal of cellular physiology 2000;185(2):269-79.
2000: H Hoffmann; J Green; Andre J van Wijnen; Janet L Stein; Gary S Stein; Jane B Lian
Expression screening of factors binding to the osteocalcin bone-specific promoter element OC box I: isolation of a novel osteoblast differentiation-specific factor.
Journal of cellular biochemistry 2000;80(1):156-68.
2000: Hicham Drissi; Q Luc; R Shakoori; S Chuva De Sousa Lopes; Je-Yong Choi; Anne Terry; M Hu; S Jones; James C Neil; Jane B Lian; Janet L Stein; Andre J van Wijnen; Gary S Stein
Transcriptional autoregulation of the bone related CBFA1/RUNX2 gene.
Journal of cellular physiology 2000;184(3):341-50.
2000: Sandra McNeil; Amjad Javed; Kimberly S Harrington; Jane B Lian; Janet L Stein; Andre J van Wijnen; Gary S Stein
Leukemia-associated AML1/ETO (8;21) chromosomal translocation protein increases the cellular representation of PML bodies.
Journal of cellular biochemistry 2000;79(1):103-12.
2000: Gary S Stein; Andre J van Wijnen; Janet L Stein; Jane B Lian; Martin Montecino; Je Choi; Kaleem Zaidi; Amjad Javed
Intranuclear trafficking of transcription factors: implications for biological control.
Journal of cell science 2000;113 ( Pt 14)():2527-33.
2000: Gary S Stein; Jane B Lian; Janet L Stein; Andre J van Wijnen
Bone tissue specific transcriptional control: options for targeting gene therapy to the skeleton.
Cancer 2000;88(12 Suppl):2899-902.
2000: Amjad Javed; B Guo; Scott W Hiebert; Je-Yong Choi; J Green; S C Zhao; M A Osborne; S Stifani; Janet L Stein; Jane B Lian; Andre J van Wijnen; Gary S Stein
Groucho/TLE/R-esp proteins associate with the nuclear matrix and repress RUNX (CBF(alpha)/AML/PEBP2(alpha)) dependent activation of tissue-specific gene transcription.
Journal of cell science 2000;113 ( Pt 12)():2221-31.
2000: Gary S Stein; Martin Montecino; Andre J van Wijnen; Janet L Stein; Jane B Lian
Nuclear structure-gene expression interrelationships: implications for aberrant gene expression in cancer.
Cancer research 2000;60(8):2067-76.
2000: J A Gordon; Shirwin M Pockwinse; F Marc Stewart; Peter J Quesenberry; T Nakamura; C M Croce; Jane B Lian; Janet L Stein; Andre J van Wijnen; Gary S Stein
Modified intranuclear organization of regulatory factors in human acute leukemias: reversal after treatment.
Journal of cellular biochemistry 2000;77(1):30-43.
2000: Gary S Stein; Andre J van Wijnen; Janet L Stein; Jane B Lian; Martin Montecino; Kaleem Zaidi; Amjad Javed
Subnuclear organization and trafficking of regulatory proteins: implications for biological control and cancer.
Journal of cellular biochemistry. Supplement 2000;Suppl 35():84-92.
1999: Sandra McNeil; C Zeng; Kimberly S Harrington; Scott W Hiebert; Jane B Lian; Janet L Stein; Andre J van Wijnen; Gary S Stein
The t(8;21) chromosomal translocation in acute myelogenous leukemia modifies intranuclear targeting of the AML1/CBFalpha2 transcription factor.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(26):14882-7.
1999: M F van Gurp; Jitesh Pratap; Mai X Luong; Amjad Javed; H Hoffmann; Antonio Giordano; Janet L Stein; E J Neufeld; Jane B Lian; Gary S Stein; Andre J van Wijnen
The CCAAT displacement protein/cut homeodomain protein represses osteocalcin gene transcription and forms complexes with the retinoblastoma protein-related protein p107 and cyclin A.
Cancer research 1999;59(23):5980-8.
1999: Gary S Stein; Andre J van Wijnen; Janet L Stein; Jane B Lian; Amjad Javed; Sandra McNeil; Shirwin M Pockwinse
Insight into regulatory factor targeting to transcriptionally active subnuclear sites.
Experimental cell research 1999;253(1):110-6.
1999: L Tang; B Guo; Amjad Javed; Je-Yong Choi; Scott W Hiebert; Jane B Lian; Andre J van Wijnen; Janet L Stein; Gary S Stein; G Wayne Zhou
Crystal structure of the nuclear matrix targeting signal of the transcription factor acute myelogenous leukemia-1/polyoma enhancer-binding protein 2alphaB/core binding factor alpha2.
The Journal of biological chemistry 1999;274(47):33580-6.
1999: Amjad Javed; S Gutierrez; Martin Montecino; Andre J van Wijnen; Janet L Stein; Gary S Stein; Jane B Lian
Multiple Cbfa/AML sites in the rat osteocalcin promoter are required for basal and vitamin D-responsive transcription and contribute to chromatin organization.
Molecular and cellular biology 1999;19(11):7491-500.
1999: Gary S Stein; Andre J van Wijnen; Martin Montecino; Janet L Stein; Jane B Lian
Nuclear structure/gene expression interrelationships.
Journal of cellular physiology 1999;181(2):240-50.
1999: T J Last; Andre J van Wijnen; M C de Ridder; Gary S Stein; Janet L Stein
The homeodomain transcription factor CDP/cut interacts with the cell cycle regulatory element of histone H4 genes packaged into nucleosomes.
Molecular biology reports 1999;26(3):185-94.
1999: Hicham Drissi; D Hushka; F Aslam; Q Nguyen; E Buffone; Andrew Koff; Andre J van Wijnen; Jane B Lian; Janet L Stein; Gary S Stein
The cell cycle regulator p27kip1 contributes to growth and differentiation of osteoblasts.
Cancer research 1999;59(15):3705-11.
1999: Z Hou; Q Nguyen; B Frenkel; SK Nilsson; M Milne; Andre J van Wijnen; Janet L Stein; Peter J Quesenberry; Jane B Lian; Gary S Stein
Osteoblast-specific gene expression after transplantation of marrow cells: implications for skeletal gene therapy.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(13):7294-9.
1999: T J Last; Andre J van Wijnen; M J Birnbaum; Gary S Stein; Janet L Stein
Multiple interactions of the transcription factor YY1 with human histone H4 gene regulatory elements.
Journal of cellular biochemistry 1999;72(4):507-16.
1999: Martin Montecino; B Frenkel; Andre J van Wijnen; Jane B Lian; Gary S Stein; Janet L Stein
Chromatin hyperacetylation abrogates vitamin D-mediated transcriptional upregulation of the tissue-specific osteocalcin gene in vivo.
Biochemistry 1999;38(4):1338-45.
1999: Gary S Stein; Andre J van Wijnen; Janet L Stein; Jane B Lian
Interrelationships of transcriptional machinery with nuclear architecture.
Critical reviews in eukaryotic gene expression 1999;9(3-4):183-90.
1999: Gary S Stein; Andre J van Wijnen; Janet L Stein; Jane B Lian; Sandra McNeil; Shirwin M Pockwinse
Transcriptional control within the three-dimensional context of nuclear architecture: requirements for boundaries and direction.
Journal of cellular biochemistry 1999;Suppl 32-33():24-31.
1999: Gary S Stein; Andre J van Wijnen; Janet L Stein; Jane B Lian; S H Pockwinse; Sandra McNeil
Implications for interrelationships between nuclear architecture and control of gene expression under microgravity conditions.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1999;13 Suppl():S157-66.
1999: Jane B Lian; Gary S Stein; Janet L Stein; Andre J van Wijnen
Regulated expression of the bone-specific osteocalcin gene by vitamins and hormones.
Vitamins and hormones 1999;55():443-509.
1999: F Aslam; L McCabe; B Frenkel; Andre J van Wijnen; Gary S Stein; Jane B Lian; Janet L Stein
AP-1 and vitamin D receptor (VDR) signaling pathways converge at the rat osteocalcin VDR element: requirement for the internal activating protein-1 site for vitamin D-mediated trans-activation.
Endocrinology 1999;140(1):63-70.
1998: F Aziz; Andre J van Wijnen; Janet L Stein; Gary S Stein
HiNF-D (CDP-cut/CDC2/cyclin A/pRB-complex) influences the timing of IRF-2-dependent cell cycle activation of human histone H4 gene transcription at the G1/S phase transition.
Journal of cellular physiology 1998;177(3):453-64.
1998: Caroline M van der Meijden; PS Vaughan; A Staal; Werner Albig; Detlef Doenecke; Janet L Stein; Gary S Stein; Andre J van Wijnen
Selective expression of specific histone H4 genes reflects distinctions in transcription factor interactions with divergent H4 promoter elements.
Biochimica et biophysica acta 1998;1442(1):82-100.
1998: Je-Yong Choi; Andre J van Wijnen; F Aslam; John Leszyk; Janet L Stein; Gary S Stein; Jane B Lian; Sheldon Penman
Developmental association of the beta-galactoside-binding protein galectin-1 with the nuclear matrix of rat calvarial osteoblasts.
Journal of cell science 1998;111 ( Pt 20)():3035-43.
1998: Gary S Stein; Andre J van Wijnen; Janet L Stein; Jane B Lian; Shirwin M Pockwinse; Sandra McNeil
Interrelationships of nuclear structure and transcriptional control: functional consequences of being in the right place at the right time.
Journal of cellular biochemistry 1998;70(2):200-12.
1998: D Lindenmuth; Andre J van Wijnen; Sheldon Penman; Janet L Stein; Gary S Stein; Jane B Lian
TGF-beta1 modifications in nuclear matrix proteins of osteoblasts during differentiation.
Journal of cellular biochemistry 1998;69(3):291-303.
1998: V Shalhoub; F Aslam; E Breen; Andre J van Wijnen; R Bortell; Gary S Stein; Janet L Stein; Jane B Lian
Multiple levels of steroid hormone-dependent control of osteocalcin during osteoblast differentiation: glucocorticoid regulation of basal and vitamin D stimulated gene expression.
Journal of cellular biochemistry 1998;69(2):154-68.
1998: Sandra McNeil; B Guo; Janet L Stein; Jane B Lian; S Bushmeyer; E Seto; M L Atchison; Sheldon Penman; Andre J van Wijnen; Gary S Stein
Targeting of the YY1 transcription factor to the nucleolus and the nuclear matrix in situ: the C-terminus is a principal determinant for nuclear trafficking.
Journal of cellular biochemistry 1998;68(4):500-10.
1998: C Zeng; Sandra McNeil; Shirwin M Pockwinse; Jeffrey A Nickerson; Lindsay S Shopland; Jeanne B Lawrence; Sheldon Penman; Scott W Hiebert; Jane B Lian; Andre J van Wijnen; Janet L Stein; Gary S Stein
Intranuclear targeting of AML/CBFalpha regulatory factors to nuclear matrix-associated transcriptional domains.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(4):1585-9.
1998: PS Vaughan; Caroline M van der Meijden; F Aziz; H Harada; T Taniguchi; Andre J van Wijnen; Janet L Stein; Gary S Stein
Cell cycle regulation of histone H4 gene transcription requires the oncogenic factor IRF-2.
The Journal of biological chemistry 1998;273(1):194-9.
1998: Gary S Stein; Andre J van Wijnen; Janet L Stein; Jane B Lian; Shirwin M Pockwinse; Sandra McNeil
Linkages of nuclear architecture to biological and pathological control of gene expression.
Journal of cellular biochemistry. Supplement 1998;30-31():220-31.
1998: Jane B Lian; Gary S Stein; Janet L Stein; Andre J van Wijnen
Osteocalcin gene promoter: unlocking the secrets for regulation of osteoblast growth and differentiation.
Journal of cellular biochemistry. Supplement 1998;30-31():62-72.
1998: Gary S Stein; Andre J van Wijnen; Janet L Stein; Jane B Lian
Nuclear structure--skeletal gene expression interrelationships.
Frontiers in bioscience : a journal and virtual library 1998;3():d849-64.
1998: F Aziz; Andre J van Wijnen; PS Vaughan; S Wu; A R Shakoori; Jane B Lian; K J Soprano; Janet L Stein; Gary S Stein
The integrated activities of IRF-2 (HiNF-M), CDP/cut (HiNF-D) and H4TF-2 (HiNF-P) regulate transcription of a cell cycle controlled human histone H4 gene: mechanistic differences between distinct H4 genes.
Molecular biology reports 1998;25(1):1-12.
1998: M P Lynch; C Capparelli; Janet L Stein; Gary S Stein; Jane B Lian
Apoptosis during bone-like tissue development in vitro.
Journal of cellular biochemistry 1998;68(1):31-49.
1997: B Guo; Janet L Stein; Andre J van Wijnen; Gary S Stein
ATF1 and CREB trans-activate a cell cycle regulated histone H4 gene at a distal nuclear matrix associated promoter element.
Biochemistry 1997;36(47):14447-55.
1997: Hyun-Mo Ryoo; H M Hoffmann; T Beumer; B Frenkel; D A Towler; Gary S Stein; Janet L Stein; Andre J van Wijnen; Jane B Lian
Stage-specific expression of Dlx-5 during osteoblast differentiation: involvement in regulation of osteocalcin gene expression.
Molecular endocrinology (Baltimore, Md.) 1997;11(11):1681-94.
1997: Andre J van Wijnen; C Cooper; Paul R Odgren; F Aziz; A De Luca; R A Shakoori; Antonio Giordano; Peter J Quesenberry; Jane B Lian; Gary S Stein; Janet L Stein
Cell cycle-dependent modifications in activities of pRb-related tumor suppressors and proliferation-specific CDP/cut homeodomain factors in murine hematopoietic progenitor cells.
Journal of cellular biochemistry 1997;66(4):512-23.
1997: Gary S Stein; Jane B Lian; Andre J van Wijnen; Janet L Stein
The osteocalcin gene: a model for multiple parameters of skeletal-specific transcriptional control.
Molecular biology reports 1997;24(3):185-96.
1997: M J Birnbaum; B van Zundert; PS Vaughan; A J Whitmarsh; Andre J van Wijnen; R J Davis; Gary S Stein; Janet L Stein
Phosphorylation of the oncogenic transcription factor interferon regulatory factor 2 (IRF2) in vitro and in vivo.
Journal of cellular biochemistry 1997;66(2):175-83.
1997: E Smith; B Frenkel; T K MacLachlan; Antonio Giordano; Janet L Stein; Jane B Lian; Gary S Stein
Post-proliferative cyclin E-associated kinase activity in differentiated osteoblasts: inhibition by proliferating osteoblasts and osteosarcoma cells.
Journal of cellular biochemistry 1997;66(2):141-52.
1997: D M Lindenmuth; Andre J van Wijnen; Scott W Hiebert; Janet L Stein; Jane B Lian; Gary S Stein
Subcellular partitioning of transcription factors during osteoblast differentiation: developmental association of the AML/CBF alpha/PEBP2 alpha-related transcription factor-NMP-2 with the nuclear matrix.
Journal of cellular biochemistry 1997;66(1):123-32.
1997: C Banerjee; L R McCabe; Je-Yong Choi; Scott W Hiebert; Janet L Stein; Gary S Stein; Jane B Lian
Runt homology domain proteins in osteoblast differentiation: AML3/CBFA1 is a major component of a bone-specific complex.
Journal of cellular biochemistry 1997;66(1):1-8.
1997: C Zeng; Andre J van Wijnen; Janet L Stein; Shari Meyers; W Sun; Lindsay S Shopland; Jeanne B Lawrence; Sheldon Penman; Jane B Lian; Gary S Stein; Scott W Hiebert
Identification of a nuclear matrix targeting signal in the leukemia and bone-related AML/CBF-alpha transcription factors.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(13):6746-51.
1997: PS Vaughan; Andre J van Wijnen; Janet L Stein; Gary S Stein
Interferon regulatory factors: growth control and histone gene regulation--it's not just interferon anymore.
Journal of molecular medicine (Berlin, Germany) 1997;75(5):348-59.
1997: Jane B Lian; V Shalhoub; F Aslam; B Frenkel; J Green; M Hamrah; Gary S Stein; Janet L Stein
Species-specific glucocorticoid and 1,25-dihydroxyvitamin D responsiveness in mouse MC3T3-E1 osteoblasts: dexamethasone inhibits osteoblast differentiation and vitamin D down-regulates osteocalcin gene expression.
Endocrinology 1997;138(5):2117-27.
1997: B Frenkel; C Capparelli; M Van Auken; D Baran; J Bryan; Janet L Stein; Gary S Stein; Jane B Lian
Activity of the osteocalcin promoter in skeletal sites of transgenic mice and during osteoblast differentiation in bone marrow-derived stromal cell cultures: effects of age and sex.
Endocrinology 1997;138(5):2109-16.
1997: Shirwin M Pockwinse; G Krockmalnic; Stephen J Doxsey; Jeffrey A Nickerson; Jane B Lian; Andre J van Wijnen; Janet L Stein; Gary S Stein; Sheldon Penman
Cell cycle independent interaction of CDC2 with the centrosome, which is associated with the nuclear matrix-intermediate filament scaffold.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(7):3022-7.
1997: B Guo; F Aslam; Andre J van Wijnen; S G Roberts; B Frenkel; M R Green; H DeLuca; Jane B Lian; Gary S Stein; Janet L Stein
YY1 regulates vitamin D receptor/retinoid X receptor mediated transactivation of the vitamin D responsive osteocalcin gene.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(1):121-6.
1997: Hyun-Mo Ryoo; Andre J van Wijnen; Janet L Stein; Jane B Lian; Gary S Stein
Detection of a proliferation specific gene during development of the osteoblast phenotype by mRNA differential display.
Journal of cellular biochemistry 1997;64(1):106-16.
1996: Andre J van Wijnen; M F van Gurp; M C de Ridder; C Tufarelli; T J Last; M Birnbaum; PS Vaughan; Antonio Giordano; W Krek; Ellis J Neufeld; Janet L Stein; Gary S Stein
CDP/cut is the DNA-binding subunit of histone gene transcription factor HiNF-D: a mechanism for gene regulation at the G1/S phase cell cycle transition point independent of transcription factor E2F.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(21):11516-21.
1996: L R McCabe; C Banerjee; R Kundu; R J Harrison; Paul R Dobner; Janet L Stein; Jane B Lian; Gary S Stein
Developmental expression and activities of specific fos and jun proteins are functionally related to osteoblast maturation: role of Fra-2 and Jun D during differentiation.
Endocrinology 1996;137(10):4398-408.
1996: Gary S Stein; Janet L Stein; Jane B Lian; Andre J van Wijnen; Martin Montecino
Functional interrelationships between nuclear structure and transcriptional control: contributions to regulation of cell cycle- and tissue-specific gene expression.
Journal of cellular biochemistry 1996;62(2):198-209.
1996: C Banerjee; Scott W Hiebert; Janet L Stein; Jane B Lian; Gary S Stein
An AML-1 consensus sequence binds an osteoblast-specific complex and transcriptionally activates the osteocalcin gene.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(10):4968-73.
1996: H M Hoffmann; Tim Beumer; S Rahman; L R McCabe; C Banerjee; F Aslam; J A Tiro; Andre J van Wijnen; Janet L Stein; Gary S Stein; Jane B Lian
Bone tissue-specific transcription of the osteocalcin gene: role of an activator osteoblast-specific complex and suppressor hox proteins that bind the OC box.
Journal of cellular biochemistry 1996;61(2):310-24.
1996: C Banerjee; Janet L Stein; Andre J van Wijnen; B Frenkel; Jane B Lian; Gary S Stein
Transforming growth factor-beta 1 responsiveness of the rat osteocalcin gene is mediated by an activator protein-1 binding site.
Endocrinology 1996;137(5):1991-2000.
1996: Gary S Stein; Jane B Lian; Janet L Stein; Andre J van Wijnen; Martin Montecino
Transcriptional control of osteoblast growth and differentiation.
Physiological reviews 1996;76(2):593-629.
1996: B Frenkel; Martin Montecino; J Green; F Aslam; R Desai; C Banerjee; Janet L Stein; Jane B Lian; Gary S Stein
Basal and vitamin D-responsive activity of the rat osteocalcin promoter in stably transfected osteosarcoma cells: requirement of upstream sequences for control by the proximal regulatory domain.
Endocrinology 1996;137(3):1080-88.
1996: Jane B Lian; Gary S Stein; Janet L Stein; Andre J van Wijnen; L McCabe; C Banerjee; H Hoffmann
The osteocalcin gene promoter provides a molecular blueprint for regulatory mechanisms controlling bone tissue formation: role of transcription factors involved in development.
Connective tissue research 1996;35(1-4):15-21.
1995: M J Birnbaum; Andre J van Wijnen; Paul R Odgren; T J Last; G Suske; Gary S Stein; Janet L Stein
Sp1 trans-activation of cell cycle regulated promoters is selectively repressed by Sp3.
Biochemistry 1995;34(50):16503-8.
1995: B Guo; Paul R Odgren; Andre J van Wijnen; T J Last; Jeffrey A Nickerson; Sheldon Penman; Jane B Lian; Janet L Stein; Gary S Stein
The nuclear matrix protein NMP-1 is the transcription factor YY1.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(23):10526-30.
1995: E Smith; B Frenkel; R Schlegel; Antonio Giordano; Jane B Lian; Janet L Stein; Gary S Stein
Expression of cell cycle regulatory factors in differentiating osteoblasts: postproliferative up-regulation of cyclins B and E.
Cancer research 1995;55(21):5019-24.
1995: PS Vaughan; F Aziz; Andre J van Wijnen; S Wu; H Harada; T Taniguchi; K J Soprano; Janet L Stein; Gary S Stein
Activation of a cell-cycle-regulated histone gene by the oncogenic transcription factor IRF-2.
Nature 1995;377(6547):362-5.
1995: K L Wright; M J Birnbaum; Andre J van Wijnen; Gary S Stein; Janet L Stein
Bipartite structure of the proximal promoter of a human H4 histone gene.
Journal of cellular biochemistry 1995;58(3):372-9.
1995: F Aslam; V Shalhoub; Andre J van Wijnen; C Banerjee; Rita Bortell; AR Shakoori; G Litwack; Janet L Stein; Gary S Stein; Jane B Lian
Contributions of distal and proximal promoter elements to glucocorticoid regulation of osteocalcin gene transcription.
Molecular endocrinology (Baltimore, Md.) 1995;9(6):679-90.
1995: A L Ramsey-Ewing; Rita Bortell; Gary S Stein; Janet L Stein
Histone H4 proximal promoter mediates a complex transcriptional response during differentiation of 3T3L1 adipocytes.
Journal of cellular physiology 1995;163(2):312-20.
1995: Paul Kroeger; Andre J van Wijnen; U Pauli; K L Wright; Gary S Stein; Janet L Stein
In vivo occupancy of histone gene proximal promoter elements reflects gene copy number-dependent titratable transactivation factors and cross-species compatibility of regulatory sequences.
Journal of cellular biochemistry 1995;57(2):191-207.
1995: M P Lynch; Janet L Stein; Gary S Stein; Jane B Lian
The influence of type I collagen on the development and maintenance of the osteoblast phenotype in primary and passaged rat calvarial osteoblasts: modification of expression of genes supporting cell growth, adhesion, and extracellular matrix mineralization.
Experimental cell research 1995;216(1):35-45.
1995: Shirwin M Pockwinse; Janet L Stein; Jane B Lian; Gary S Stein
Developmental stage-specific cellular responses to vitamin D and glucocorticoids during differentiation of the osteoblast phenotype: interrelationship of morphology and gene expression by in situ hybridization.
Experimental cell research 1995;216(1):244-60.
1995: A A Heinrichs; Rita Bortell; M Bourke; Jane B Lian; Gary S Stein; Janet L Stein
Proximal promoter binding protein contributes to developmental, tissue-restricted expression of the rat osteocalcin gene.
Journal of cellular biochemistry 1995;57(1):90-100.
1994: E C Breen; Andre J van Wijnen; Jane B Lian; Gary S Stein; Janet L Stein
In vivo occupancy of the vitamin D responsive element in the osteocalcin gene supports vitamin D-dependent transcriptional upregulation in intact cells.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(26):12902-6.
1994: H M Hoffmann; K M Catron; Andre J van Wijnen; L R McCabe; Jane B Lian; Gary S Stein; Janet L Stein
Transcriptional control of the tissue-specific, developmentally regulated osteocalcin gene requires a binding motif for the Msx family of homeodomain proteins.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(26):12887-91.
1994: B Frenkel; Martin Montecino; Janet L Stein; Jane B Lian; Gary S Stein
A composite intragenic silencer domain exhibits negative and positive transcriptional control of the bone-specific osteocalcin gene: promoter and cell type requirements.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(23):10923-7.
1994: E C Breen; R A Ignotz; L McCabe; Janet L Stein; Gary S Stein; Jane B Lian
TGF beta alters growth and differentiation related gene expression in proliferating osteoblasts in vitro, preventing development of the mature bone phenotype.
Journal of cellular physiology 1994;160(2):323-35.
1994: F M van den Ent; Andre J van Wijnen; Jane B Lian; Janet L Stein; Gary S Stein
Cell cycle controlled histone H1, H3, and H4 genes share unusual arrangements of recognition motifs for HiNF-D supporting a coordinate promoter binding mechanism.
Journal of cellular physiology 1994;159(3):515-30.
1994: AR Shakoori; Andre J van Wijnen; Rita Bortell; Thomas A Owen; Janet L Stein; Jane B Lian; Gary S Stein
Variations in vitamin D receptor transcription factor complexes associated with the osteocalcin gene vitamin D responsive element in osteoblasts and osteosarcoma cells.
Journal of cellular biochemistry 1994;55(2):218-29.
1994: V Shalhoub; Rita Bortell; M E Jackson; Sandy C Marks; Janet L Stein; Jane B Lian; Gary S Stein
Transcriptionally active nuclei isolated from intact bone reflect modified levels of gene expression in skeletal development and pathology.
Journal of cellular biochemistry 1994;55(2):182-9.
1994: A Ramsey-Ewing; Andre J van Wijnen; Gary S Stein; Janet L Stein
Delineation of a human histone H4 cell cycle element in vivo: the master switch for H4 gene transcription.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(10):4475-9.
1994: Gary S Stein; Andre J van Wijnen; Janet L Stein; Jane B Lian; J P Bidwell; Martin Montecino
Nuclear architecture supports integration of physiological regulatory signals for transcription of cell growth and tissue-specific genes during osteoblast differentiation.
Journal of cellular biochemistry 1994;55(1):4-15.
1994: J P Bidwell; Andre J van Wijnen; E G Fey; H Merriman; Sheldon Penman; Janet L Stein; Gary S Stein; Jane B Lian
Subnuclear distribution of the vitamin D receptor.
Journal of cellular biochemistry 1994;54(4):494-500.
1994: Gary S Stein; Janet L Stein; Andre J van Wijnen; Jane B Lian
Histone gene transcription: a model for responsiveness to an integrated series of regulatory signals mediating cell cycle control and proliferation/differentiation interrelationships.
Journal of cellular biochemistry 1994;54(4):393-404.
1994: Rita Bortell; Thomas A Owen; R Ignotz; Gary S Stein; Janet L Stein
TGF beta 1 prevents the down-regulation of type I procollagen, fibronectin, and TGF beta 1 gene expression associated with 3T3-L1 pre-adipocyte differentiation.
Journal of cellular biochemistry 1994;54(2):256-63.
1994: J P Bidwell; E G Fey; Andre J van Wijnen; Sheldon Penman; Janet L Stein; Jane B Lian; Gary S Stein
Nuclear matrix proteins distinguish normal diploid osteoblasts from osteosarcoma cells.
Cancer research 1994;54(1):28-32.
1994: M Kockx; L McCabe; Janet L Stein; Jane B Lian; Gary S Stein
Influence of DNA replication inhibition on expression of cell growth and tissue-specific genes in osteoblasts and osteosarcoma cells.
Journal of cellular biochemistry 1994;54(1):47-55.
1993: B Frenkel; J Mijnes; M A Aronow; G Zambetti; C Banerjee; Janet L Stein; Jane B Lian; Gary S Stein
Position and orientation-selective silencer in protein-coding sequences of the rat osteocalcin gene.
Biochemistry 1993;32(49):13636-43.
1993: S Rahman; A Oberdorf; M Montecino; S M Tanhauser; Jane B Lian; Gary S Stein; Philip J Laipis; Janet L Stein
Multiple copies of the bone-specific osteocalcin gene in mouse and rat.
Endocrinology 1993;133(6):3050-3.
1993: A A Heinrichs; C Banerjee; Rita Bortell; Thomas A Owen; Janet L Stein; Gary S Stein; Jane B Lian
Identification and characterization of two proximal elements in the rat osteocalcin gene promoter that may confer species-specific regulation.
Journal of cellular biochemistry 1993;53(3):240-50.
1993: A A Heinrichs; Rita Bortell; S Rahman; Janet L Stein; E S Alnemri; G Litwack; Jane B Lian; Gary S Stein
Identification of multiple glucocorticoid receptor binding sites in the rat osteocalcin gene promoter.
Biochemistry 1993;32(42):11436-44.
1993: Andre J van Wijnen; J P Bidwell; E G Fey; Sheldon Penman; Jane B Lian; Janet L Stein; Gary S Stein
Nuclear matrix association of multiple sequence-specific DNA binding activities related to SP-1, ATF, CCAAT, C/EBP, OCT-1, and AP-1.
Biochemistry 1993;32(33):8397-402.
1993: F M van den Ent; Andre J van Wijnen; T J Last; Rita Bortell; Janet L Stein; Jane B Lian; Gary S Stein
Concerted control of multiple histone promoter factors during cell density inhibition of proliferation in osteosarcoma cells: reciprocal regulation of cell cycle-controlled and bone-related genes.
Cancer research 1993;53(10 Suppl):2399-409.
1993: Shirwin M Pockwinse; Jeanne B Lawrence; Robert H Singer; Janet L Stein; Jane B Lian; Gary S Stein
Gene expression at single cell resolution associated with development of the bone cell phenotype: ultrastructural and in situ hybridization analysis.
Bone 1993;14(3):347-52.
1993: J P Bidwell; Andre J van Wijnen; E G Fey; S Dworetzky; Sheldon Penman; Janet L Stein; Jane B Lian; Gary S Stein
Osteocalcin gene promoter-binding factors are tissue-specific nuclear matrix components.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(8):3162-6.
1993: AR Shakoori; Thomas A Owen; V Shalhoub; Janet L Stein; M Bustin; Gary S Stein; Jane B Lian
Differential expression of the chromosomal high mobility group proteins 14 and 17 during the onset of differentiation in mammalian osteoblasts and promyelocytic leukemia cells.
Journal of cellular biochemistry 1993;51(4):479-87.
1993: Rita Bortell; Thomas A Owen; V Shalhoub; A Heinrichs; M A Aronow; Cécile Rochette-Egly; Yves Lutz; Janet L Stein; Jane B Lian; Gary S Stein
Constitutive transcription of the osteocalcin gene in osteosarcoma cells is reflected by altered protein-DNA interactions at promoter regulatory elements.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(6):2300-4.
1993: Thomas A Owen; Rita Bortell; V Shalhoub; A Heinrichs; Janet L Stein; Gary S Stein; Jane B Lian
Postproliferative transcription of the rat osteocalcin gene is reflected by vitamin D-responsive developmental modifications in protein-DNA interactions at basal and enhancer promoter elements.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(4):1503-7.
1992: Rita Bortell; Andre J van Wijnen; A L Ramsey-Ewing; Gary S Stein; Janet L Stein
Differential regulation of H4 histone gene expression in 3T3-L1 pre-adipocytes during arrest of proliferation following contact inhibition or differentiation and its modulation by TGF beta 1.
Journal of cellular biochemistry 1992;50(1):62-72.
1992: Andre J van Wijnen; F M van den Ent; Jane B Lian; Janet L Stein; Gary S Stein
Overlapping and CpG methylation-sensitive protein-DNA interactions at the histone H4 transcriptional cell cycle domain: distinctions between two human H4 gene promoters.
Molecular and cellular biology 1992;12(7):3273-87.
1992: Rita Bortell; Thomas A Owen; J P Bidwell; P Gavazzo; E Breen; Andre J van Wijnen; H F DeLuca; Janet L Stein; Jane B Lian; Gary S Stein
Vitamin D-responsive protein-DNA interactions at multiple promoter regulatory elements that contribute to the level of rat osteocalcin gene expression.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(13):6119-23.
1992: S P Gerbaulet; Andre J van Wijnen; N Aronin; M S Tassinari; Jane B Lian; Janet L Stein; Gary S Stein
Downregulation of histone H4 gene transcription during postnatal development in transgenic mice and at the onset of differentiation in transgenically derived calvarial osteoblast cultures.
Journal of cellular biochemistry 1992;49(2):137-47.
1992: C W van der Houven van Oordt; Andre J van Wijnen; R Carter; K Soprano; Jane B Lian; Gary S Stein; Janet L Stein
Protein-DNA interactions at the H4-site III upstream transcriptional element of a cell cycle regulated histone H4 gene: differences in normal versus tumor cells.
Journal of cellular biochemistry 1992;49(1):93-110.
1992: S I Dworetzky; K L Wright; E G Fey; Sheldon Penman; Jane B Lian; Janet L Stein; Gary S Stein
Sequence-specific DNA-binding proteins are components of a nuclear matrix-attachment site.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(9):4178-82.
1992: K L Wright; R T Dell'Orco; Andre J van Wijnen; Janet L Stein; Gary S Stein
Multiple mechanisms regulate the proliferation-specific histone gene transcription factor HiNF-D in normal human diploid fibroblasts.
Biochemistry 1992;31(10):2812-8.
1992: Andre J van Wijnen; J Bidwell; Jane B Lian; Janet L Stein; Gary S Stein
Stairway assays: rapid localization of multiple protein/DNA interaction sites in gene-regulatory 5' regions.
BioTechniques 1992;12(3):400-7.
1992: AR Shakoori; A M Oberdorf; Thomas A Owen; Lee A Weber; E Hickey; Janet L Stein; Jane B Lian; Gary S Stein
Expression of heat shock genes during differentiation of mammalian osteoblasts and promyelocytic leukemia cells.
Journal of cellular biochemistry 1992;48(3):277-87.
1991: Andre J van Wijnen; Jane B Lian; Janet L Stein; Gary S Stein
Protein/DNA interactions involving ATF/AP1-, CCAAT-, and HiNF-D-related factors in the human H3-ST519 histone promoter: cross-competition with transcription regulatory sites in cell cycle controlled H4 and H1 histone genes.
Journal of cellular biochemistry 1991;47(4):337-51.
1991: Andre J van Wijnen; Thomas A Owen; J Holthuis; Jane B Lian; Janet L Stein; Gary S Stein
Coordination of protein-DNA interactions in the promoters of human H4, H3, and H1 histone genes during the cell cycle, tumorigenesis, and development.
Journal of cellular physiology 1991;148(1):174-89.
1991: Andre J van Wijnen; A L Ramsey-Ewing; Rita Bortell; Thomas A Owen; Jane B Lian; Janet L Stein; Gary S Stein
Transcriptional element H4-site II of cell cycle regulated human H4 histone genes is a multipartite protein/DNA interaction site for factors HiNF-D, HiNF-M, and HiNF-P: involvement of phosphorylation.
Journal of cellular biochemistry 1991;46(2):174-89.
1991: Andre J van Wijnen; T K Choi; Thomas A Owen; K L Wright; Jane B Lian; Rudolf Jaenisch; Janet L Stein; Gary S Stein
Involvement of the cell cycle-regulated nuclear factor HiNF-D in cell growth control of a human H4 histone gene during hepatic development in transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(6):2573-7.
1991: T D Morris; Lee A Weber; E Hickey; Gary S Stein; Janet L Stein
Changes in the stability of a human H3 histone mRNA during the HeLa cell cycle.
Molecular and cellular biology 1991;11(1):544-53.
1990: S I Dworetzky; E G Fey; Sheldon Penman; Jane B Lian; Janet L Stein; Gary S Stein
Progressive changes in the protein composition of the nuclear matrix during rat osteoblast differentiation.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(12):4605-9.
1990: E R Markose; Janet L Stein; Gary S Stein; Jane B Lian
Vitamin D-mediated modifications in protein-DNA interactions at two promoter elements of the osteocalcin gene.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(5):1701-5.
1989: Gary S Stein; Janet L Stein; Jane B Lian; Andre J van Wijnen; K L Wright; U Pauli
Modifications in molecular mechanisms associated with control of cell cycle regulated human histone gene expression during differentiation.
Cell biophysics 1989;15(3):201-23.
1989: Andre J van Wijnen; K L Wright; Jane B Lian; Janet L Stein; Gary S Stein
Human H4 histone gene transcription requires the proliferation-specific nuclear factor HiNF-D. Auxiliary roles for HiNF-C (Sp1-like) and HiNF-A (high mobility group-like).
The Journal of biological chemistry 1989;264(25):15034-42.
1988: D G Collar; K L Wright; Andre J van Wijnen; A L Ramsey; J Lian; Janet L Stein; Gary S Stein
The human H1 histone gene FNC16 is functionally expressed in proliferating HeLa S3 cells and is down-regulated during terminal differentiation in HL60 cells.
The Journal of biological chemistry 1988;263(31):15860-3.
1988: Andre J van Wijnen; R F Massung; Janet L Stein; Gary S Stein
Human H1 histone gene promoter CCAAT box binding protein HiNF-B is a mosaic factor.
Biochemistry 1988;27(17):6534-41.
1988: M L Moreno; U Pauli; S Chrysogelos; Janet L Stein; Gary S Stein
Persistence of a micrococcal nuclease sensitive region spanning the promoter-coding region junction of a cell cycle regulated human H4 histone gene throughout the cell cycle.
Biochemistry and cell biology = Biochimie et biologie cellulaire 1988;66(2):132-7.
1988: Andre J van Wijnen; K L Wright; R F Massung; M Gerretsen; Janet L Stein; Gary S Stein
Two target sites for protein binding in the promoter region of a cell cycle regulated human H1 histone gene.
Nucleic acids research 1988;16(2):571-92.
1988: Jeanne B Lawrence; Robert H Singer; C A Villnave; Janet L Stein; Gary S Stein
Intracellular distribution of histone mRNAs in human fibroblasts studied by in situ hybridization.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(2):463-7.
1987: Lisa Baumbach; Gary S Stein; Janet L Stein
Regulation of human histone gene expression: transcriptional and posttranscriptional control in the coupling of histone messenger RNA stability with DNA replication.
Biochemistry 1987;26(19):6178-87.
1987: S R Helms; Andre J van Wijnen; P Kroeger; A Shiels; C Stewart; J Hirshman; Janet L Stein; Gary S Stein
Identification of an enhancer-like element upstream from a cell cycle dependent human H4 histone gene.
Journal of cellular physiology 1987;132(3):552-8.
1986: M L Moreno; S A Chrysogelos; Gary S Stein; Janet L Stein
Reversible changes in the nucleosomal organization of a human H4 histone gene during the cell cycle.
Biochemistry 1986;25(19):5364-70.