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Joan Steitz

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Kasandra J. Riley; Joan A Steitz
The "Observer Effect" in genome-wide surveys of protein-RNA interactions.
Andrei Alexandrov; David Colognori; Mei-Di Shu; Joan A Steitz
Human spliceosomal protein CWC22 plays a role in coupling splicing to exon junction complex deposition and nonsense-mediated decay.
Jessica A Brown; Kazimierz T Tycowski; Max L Valenstein; Therese A Yario; Joan A Steitz
Formation of triple-helical structures by the 3'-end sequences of MALAT1 and MENβ noncoding RNAs.

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All Publications

2013: Kasandra J. Riley; Joan A Steitz
The "Observer Effect" in genome-wide surveys of protein-RNA interactions.
Molecular cell 2013;49(4):601-4.
2012: Andrei Alexandrov; David Colognori; Mei-Di Shu; Joan A Steitz
Human spliceosomal protein CWC22 plays a role in coupling splicing to exon junction complex deposition and nonsense-mediated decay.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(52):21313-8.
2012: Jessica A Brown; Kazimierz T Tycowski; Max L Valenstein; Therese A Yario; Joan A Steitz
Formation of triple-helical structures by the 3'-end sequences of MALAT1 and MENβ noncoding RNAs.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(47):19202-7.
2012: Kasandra J. Riley; Therese A Yario; Joan A Steitz
Association of Argonaute proteins and microRNAs can occur after cell lysis.
RNA (New York, N.Y.) 2012;18(9):1581-5.
2012: Kazimierz T Tycowski; Sumit Borah; Mary Shi; Mei-Di Shu; Joan A Steitz
Conservation of a triple-helix-forming RNA stability element in noncoding and genomic RNAs of diverse viruses.
Cell reports 2012;2(1):26-32.
2012: Kasandra J. Riley; Robert B Darnell; Joseph M Luna; Gabrielle S Rabinowitz; Therese A Yario; Joan A Steitz
EBV and human microRNAs co-target oncogenic and apoptotic viral and human genes during latency.
The EMBO journal 2012;31(9):2207-21.
2012: Anita Nag; Joan A Steitz
Tri-snRNP-associated proteins interact with subunits of the TRAMP and nuclear exosome complexes, linking RNA decay and pre-mRNA splicing.
RNA biology 2012;9(3):334-42.
2011: Sumit Borah; Alicia Darnell; Nicole Darricarrère; Jinjong Myoung; Joan A Steitz
A viral nuclear noncoding RNA binds re-localized poly(A) binding protein and is required for late KSHV gene expression.
PLoS pathogens 2011;7(10):e1002300.
2011: Demian Cazalla; Mingyi Xie; Joan A Steitz
A primate herpesvirus uses the integrator complex to generate viral microRNAs.
Molecular cell 2011;43(6):982-92.
2011: Andrei Alexandrov; David Colognori; Joan A Steitz
Human eIF4AIII interacts with an eIF4G-like partner, NOM1, revealing an evolutionarily conserved function outside the exon junction complex.
Genes & development 2011;25(10):1078-90.
2011: Ivan Martinez; Demian Cazalla; Laura L Almstead; Joan A Steitz; Daniel DiMaio
miR-29 and miR-30 regulate B-Myb expression during cellular senescence.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(2):522-7.
2010: Rachel M Mitton-Fry; Suzanne J DeGregorio; Jimin Wang; Thomas A Steitz; Joan A Steitz
Poly(A) tail recognition by a viral RNA element through assembly of a triple helix.
Science (New York, N.Y.) 2010;330(6008):1244-7.
2010: Demian Cazalla; Joan A Steitz
Down-regulation of a host microRNA by a viral noncoding RNA.
Cold Spring Harbor symposia on quantitative biology 2010;75():321-4.
2010: Jan M Pawlicki; Joan A Steitz
Nuclear networking fashions pre-messenger RNA and primary microRNA transcripts for function.
Trends in cell biology 2010;20(1):52-61.
2009: Joan A Steitz; Shobha Vasudevan
miRNPs: versatile regulators of gene expression in vertebrate cells.
Biochemical Society transactions 2009;37(Pt 5):931-5.
2009: Kazimierz T Tycowski; Mei-Di Shu; Abiodun Kukoyi; Joan A Steitz
A conserved WD40 protein binds the Cajal body localization signal of scaRNP particles.
Molecular cell 2009;34(1):47-57.
2009: Sumit Borah; Anthony C Wong; Joan A Steitz
Drosophila hnRNP A1 homologs Hrp36/Hrp38 enhance U2-type versus U12-type splicing to regulate alternative splicing of the prospero twintron.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(8):2577-82.
2009: Jan M Pawlicki; Joan A Steitz
Subnuclear compartmentalization of transiently expressed polyadenylated pri-microRNAs: processing at transcription sites or accumulation in SC35 foci.
Cell cycle (Georgetown, Tex.) 2009;8(3):345-56.
2008: Dennis M Mishler; Alexander B Christ; Joan A Steitz
Flexibility in the site of exon junction complex deposition revealed by functional group and RNA secondary structure alterations in the splicing substrate.
RNA (New York, N.Y.) 2008;14(12):2657-70.
2008: Nikolay G Kolev; Therese A Yario; Eleni Benson; Joan A Steitz
Conserved motifs in both CPSF73 and CPSF100 are required to assemble the active endonuclease for histone mRNA 3'-end maturation.
EMBO reports 2008;9(10):1013-8.
2008: Kyle Friend; Nikolay G Kolev; Mei-Di Shu; Joan A Steitz
Minor-class splicing occurs in the nucleus of the Xenopus oocyte.
RNA (New York, N.Y.) 2008;14(8):1459-62.
2008: Jan M Pawlicki; Joan A Steitz
Primary microRNA transcript retention at sites of transcription leads to enhanced microRNA production.
The Journal of cell biology 2008;182(1):61-76.
2008: Joan A Steitz; Gideon Dreyfuss; Adrian R Krainer; Angus I Lamond; A Gregory Matera; Richard A Padgett
Where in the cell is the minor spliceosome?
Proceedings of the National Academy of Sciences of the United States of America 2008;105(25):8485-6.
2008: Shobha Vasudevan; Yingchun Tong; Joan A Steitz
Cell-cycle control of microRNA-mediated translation regulation.
Cell cycle (Georgetown, Tex.) 2008;7(11):1545-9.
2007: Shobha Vasudevan; Yingchun Tong; Joan A Steitz
Switching from repression to activation: microRNAs can up-regulate translation.
Science (New York, N.Y.) 2007;318(5858):1931-4.
2007: Kyle Friend; Alexander F Lovejoy; Joan A Steitz
U2 snRNP binds intronless histone pre-mRNAs to facilitate U7-snRNP-dependent 3' end formation.
Molecular cell 2007;28(2):240-52.
2007: nicholas conrad; Mei-Di Shu; Katherine E Uyhazi; Joan A Steitz
Mutational analysis of a viral RNA element that counteracts rapid RNA decay by interaction with the polyadenylate tail.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(25):10412-7.
2007: J Robin Lytle; Therese A Yario; Joan A Steitz
Target mRNAs are repressed as efficiently by microRNA-binding sites in the 5' UTR as in the 3' UTR.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(23):9667-72.
2007: Shobha Vasudevan; Joan A Steitz
AU-rich-element-mediated upregulation of translation by FXR1 and Argonaute 2.
Cell 2007;128(6):1105-18.
2006: nicholas conrad; Stavroula Mili; Eleanor L Marshall; Mei-Di Shu; Joan A Steitz
Identification of a rapid mammalian deadenylation-dependent decay pathway and its inhibition by a viral RNA element.
Molecular cell 2006;24(6):943-53.
2006: Victor Fok; Kyle Friend; Joan A Steitz
Epstein-Barr virus noncoding RNAs are confined to the nucleus, whereas their partner, the human La protein, undergoes nucleocytoplasmic shuttling.
The Journal of cell biology 2006;173(3):319-25.
2006: Victor Fok; Rachel M Mitton-Fry; Angie Grech; Joan A Steitz
Multiple domains of EBER 1, an Epstein-Barr virus noncoding RNA, recruit human ribosomal protein L22.
RNA (New York, N.Y.) 2006;12(5):872-82.
2006: Nikolay G Kolev; Joan A Steitz
In vivo assembly of functional U7 snRNP requires RNA backbone flexibility within the Sm-binding site.
Nature structural & molecular biology 2006;13(4):347-53.
2006: Shobha Vasudevan; Emre Seli; Joan A Steitz
Metazoan oocyte and early embryo development program: a progression through translation regulatory cascades.
Genes & development 2006;20(2):138-46.
2006: nicholas conrad; Victor Fok; D Cazalla; S Borah; Joan A Steitz
The challenge of viral snRNPs.
Cold Spring Harbor symposia on quantitative biology 2006;71():377-84.
2005: Nikolay G Kolev; Joan A Steitz
Symplekin and multiple other polyadenylation factors participate in 3'-end maturation of histone mRNAs.
Genes & development 2005;19(21):2583-92.
2005: Lara B Weinstein Szewczak; J Scott Gabrielsen; Suzanne J Degregorio; Scott A Strobel; Joan A Steitz
Molecular basis for RNA kink-turn recognition by the h15.5K small RNP protein.
RNA (New York, N.Y.) 2005;11(9):1407-19.
2005: Heidi L Cook; J Robin Lytle; Hannah E Mischo; Ming-Jie Li; John J Rossi; Daniel P Silva; Ronald C Desrosiers; Joan A Steitz
Small nuclear RNAs encoded by Herpesvirus saimiri upregulate the expression of genes linked to T cell activation in virally transformed T cells.
Current biology : CB 2005;15(10):974-9.
2005: nicholas conrad; Joan A Steitz
A Kaposi's sarcoma virus RNA element that increases the nuclear abundance of intronless transcripts.
The EMBO journal 2005;24(10):1831-41.
2005: Yingqun Huang; Joan A Steitz
SRprises along a messenger's journey.
Molecular cell 2005;17(5):613-5.
2005: Emre Seli; Maria D Lalioti; Sean M Flaherty; Denny Sakkas; Nihal Terzi; Joan A Steitz
An embryonic poly(A)-binding protein (ePAB) is expressed in mouse oocytes and early preimplantation embryos.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(2):367-72.
2004: Tetsuro Hirose; Mei-Di Shu; Joan A Steitz
Splicing of U12-type introns deposits an exon junction complex competent to induce nonsense-mediated mRNA decay.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(52):17976-81.
2004: Kazimierz T Tycowski; Alar Aab; Joan A Steitz
Guide RNAs with 5' caps and novel box C/D snoRNA-like domains for modification of snRNAs in metazoa.
Current biology : CB 2004;14(22):1985-95.
2004: Stavroula Mili; Joan A Steitz
Evidence for reassociation of RNA-binding proteins after cell lysis: implications for the interpretation of immunoprecipitation analyses.
RNA (New York, N.Y.) 2004;10(11):1692-4.
2004: Yingqun Huang; Therese A Yario; Joan A Steitz
A molecular link between SR protein dephosphorylation and mRNA export.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(26):9666-70.
2004: Heidi L Cook; Hannah E Mischo; Joan A Steitz
The Herpesvirus saimiri small nuclear RNAs recruit AU-rich element-binding proteins but do not alter host AU-rich element-containing mRNA levels in virally transformed T cells.
Molecular and cellular biology 2004;24(10):4522-33.
2004: J Robin Lytle; Joan A Steitz
Premature termination codons do not affect the rate of splicing of neighboring introns.
RNA (New York, N.Y.) 2004;10(4):657-68.
2004: Ana Rebane; Alar Aab; Joan A Steitz
Transportins 1 and 2 are redundant nuclear import factors for hnRNP A1 and HuR.
RNA (New York, N.Y.) 2004;10(4):590-9.
2004: Petra Scamborova; Anthony Wong; Joan A Steitz
An intronic enhancer regulates splicing of the twintron of Drosophila melanogaster prospero pre-mRNA by two different spliceosomes.
Molecular and cellular biology 2004;24(5):1855-69.
2003: Abhijit A Patel; Joan A Steitz
Splicing double: insights from the second spliceosome.
Nature reviews. Molecular cell biology 2003;4(12):960-70.
2003: IE Gallouzi; CM Brennan; Joan A Steitz
Protein ligands mediate the CRM1-dependent export of HuR in response to heat shock.
RNA (New York, N.Y.) 2003;9(11):1410.
2003: Tetsuro Hirose; Mei-Di Shu; Joan A Steitz
Splicing-dependent and -independent modes of assembly for intron-encoded box C/D snoRNPs in mammalian cells.
Molecular cell 2003;12(1):113-23.
2003: Yingqun Huang; Renata Gattoni; James Stévenin; Joan A Steitz
SR splicing factors serve as adapter proteins for TAP-dependent mRNA export.
Molecular cell 2003;11(3):837-43.
2003: Timothy S McConnell; R Peter Lokken; Joan A Steitz
Assembly of the U1 snRNP involves interactions with the backbone of the terminal stem of U1 snRNA.
RNA (New York, N.Y.) 2003;9(2):193-201.
2003: Joan A Steitz
Commentary: Bio2010--new challenges for biology educators.
Cell biology education 2003;2(2):87-91.
2002: Lara B Weinstein Szewczak; Suzanne J DeGregorio; Scott A Strobel; Joan A Steitz
Exclusive interaction of the 15.5 kD protein with the terminal box C/D motif of a methylation guide snoRNP.
Chemistry & biology 2002;9(10):1095-107.
2002: Niamh M Cahill; Kyle Friend; Wayne A Speckmann; Zhu-Hong Li; Rebecca M Terns; Michael P Terns; Joan A Steitz
Site-specific cross-linking analyses reveal an asymmetric protein distribution for a box C/D snoRNP.
The EMBO journal 2002;21(14):3816-28.
2002: Abhijit A Patel; Matthew McCarthy; Joan A Steitz
The splicing of U12-type introns can be a rate-limiting step in gene expression.
The EMBO journal 2002;21(14):3804-15.
2002: Timothy S McConnell; Soo-Jin Cho; Mikko J Frilander; Joan A Steitz
Branchpoint selection in the splicing of U12-dependent introns in vitro.
RNA (New York, N.Y.) 2002;8(5):579-86.
2002: Leo R Otake; Petra Scamborova; Carl Hashimoto; Joan A Steitz
The divergent U12-type spliceosome is required for pre-mRNA splicing and is essential for development in Drosophila.
Molecular cell 2002;9(2):439-46.
2001: IE Gallouzi; Joan A Steitz
Delineation of mRNA export pathways by the use of cell-permeable peptides.
Science (New York, N.Y.) 2001;294(5548):1895-901.
2001: Tetsuro Hirose; Joan A Steitz
Position within the host intron is critical for efficient processing of box C/D snoRNAs in mammalian cells.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(23):12914-9.
2001: Jens Lykke-Andersen; Mei-Di Shu; Joan A Steitz
Communication of the position of exon-exon junctions to the mRNA surveillance machinery by the protein RNPS1.
Science (New York, N.Y.) 2001;293(5536):1836-9.
2001: IE Gallouzi; CM Brennan; Joan A Steitz
Protein ligands mediate the CRM1-dependent export of HuR in response to heat shock.
RNA (New York, N.Y.) 2001;7(9):1348-61.
2001: Timothy S McConnell; Joan A Steitz
Proximity of the invariant loop of U5 snRNA to the second intron residue during pre-mRNA splicing.
The EMBO journal 2001;20(13):3577-86.
2001: Yingqun Huang; Joan A Steitz
Splicing factors SRp20 and 9G8 promote the nucleocytoplasmic export of mRNA.
Molecular cell 2001;7(4):899-905.
2001: Yi-Tao Yu; Mei-Di Shu; Aarthi Narayanan; Rebecca M Terns; Michael P Terns; Joan A Steitz
Internal modification of U2 small nuclear (sn)RNA occurs in nucleoli of Xenopus oocytes.
The Journal of cell biology 2001;152(6):1279-88.
2001: G K Voeltz; J Ongkasuwan; N Standart; Joan A Steitz
A novel embryonic poly(A) binding protein, ePAB, regulates mRNA deadenylation in Xenopus egg extracts.
Genes & development 2001;15(6):774-88.
2001: Kazimierz T Tycowski; Joan A Steitz
Non-coding snoRNA host genes in Drosophila: expression strategies for modification guide snoRNAs.
European journal of cell biology 2001;80(2):119-25.
2001: CM Brennan; Joan A Steitz
HuR and mRNA stability.
Cellular and molecular life sciences : CMLS 2001;58(2):266-77.
2001: Mikko J Frilander; Joan A Steitz
Dynamic exchanges of RNA interactions leading to catalytic core formation in the U12-dependent spliceosome.
Molecular cell 2001;7(1):217-26.
2000: Jens Lykke-Andersen; Mei-Di Shu; Joan A Steitz
Human Upf proteins target an mRNA for nonsense-mediated decay when bound downstream of a termination codon.
Cell 2000;103(7):1121-31.
2000: CM Brennan; IE Gallouzi; Joan A Steitz
Protein ligands to HuR modulate its interaction with target mRNAs in vivo.
The Journal of cell biology 2000;151(1):1-14.
2000: IE Gallouzi; CM Brennan; Myrna G Stenberg; Maurice S Swanson; A Eversole; Nancy Maizels; Joan A Steitz
HuR binding to cytoplasmic mRNA is perturbed by heat shock.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(7):3073-8.
1999: L B Weinstein; Joan A Steitz
Guided tours: from precursor snoRNA to functional snoRNP.
Current opinion in cell biology 1999;11(3):378-84.
1999: Mikko J Frilander; Joan A Steitz
Initial recognition of U12-dependent introns requires both U11/5' splice-site and U12/branchpoint interactions.
Genes & development 1999;13(7):851-63.
1998: Xinhao Cynthia Fan; Joan A Steitz
HNS, a nuclear-cytoplasmic shuttling sequence in HuR.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(26):15293-8.
1998: G K Voeltz; Joan A Steitz
AUUUA sequences direct mRNA deadenylation uncoupled from decay during Xenopus early development.
Molecular and cellular biology 1998;18(12):7537-45.
1998: C M Smith; Joan A Steitz
Classification of gas5 as a multi-small-nucleolar-RNA (snoRNA) host gene and a member of the 5'-terminal oligopyrimidine gene family reveals common features of snoRNA host genes.
Molecular and cellular biology 1998;18(12):6897-909.
1998: Kazimierz T Tycowski; Z H You; P J Graham; Joan A Steitz
Modification of U6 spliceosomal RNA is guided by other small RNAs.
Molecular cell 1998;2(5):629-38.
1998: Yi-Tao Yu; Mei-Di Shu; Joan A Steitz
Modifications of U2 snRNA are required for snRNP assembly and pre-mRNA splicing.
The EMBO journal 1998;17(19):5783-95.
1998: Xinhao Cynthia Fan; Joan A Steitz
Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the in vivo stability of ARE-containing mRNAs.
The EMBO journal 1998;17(12):3448-60.
1997: A R Parker; Joan A Steitz
Inhibition of mammalian spliceosome assembly and pre-mRNA splicing by peptide inhibitors of protein kinases.
RNA (New York, N.Y.) 1997;3(11):1301-12.
1997: Xinhao Cynthia Fan; Vic Myer; Joan A Steitz
AU-rich elements target small nuclear RNAs as well as mRNAs for rapid degradation.
Genes & development 1997;11(19):2557-68.
1997: J Lapham; Yi-Tao Yu; Mei-Di Shu; Joan A Steitz; Donald M Crothers
The position of site-directed cleavage of RNA using RNase H and 2'-O-methyl oligonucleotides is dependent on the enzyme source.
RNA (New York, N.Y.) 1997;3(9):950-1.
1997: Yi-Tao Yu; Joan A Steitz
A new strategy for introducing photoactivatable 4-thiouridine ((4S)U) into specific positions in a long RNA molecule.
RNA (New York, N.Y.) 1997;3(7):807-10.
1997: Yi-Tao Yu; Joan A Steitz
Site-specific crosslinking of mammalian U11 and u6atac to the 5' splice site of an AT-AC intron.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(12):6030-5.
1997: C M Smith; Joan A Steitz
Sno storm in the nucleolus: new roles for myriad small RNPs.
Cell 1997;89(5):669-72.
1997: Vic Myer; Xinhao Cynthia Fan; Joan A Steitz
Identification of HuR as a protein implicated in AUUUA-mediated mRNA decay.
The EMBO journal 1997;16(8):2130-9.
1997: Yi-Tao Yu; Mei-Di Shu; Joan A Steitz
A new method for detecting sites of 2'-O-methylation in RNA molecules.
RNA (New York, N.Y.) 1997;3(3):324-31.
1996: Yi-Tao Yu; W Y Tarn; T A Yario; Joan A Steitz
More Sm snRNAs from vertebrate cells.
Experimental cell research 1996;229(2):276-81.
1996: E C Scharl; Joan A Steitz
Length suppression in histone messenger RNA 3'-end maturation: processing defects of insertion mutant premessenger RNAs can be compensated by insertions into the U7 small nuclear RNA.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(25):14659-64.
1996: K T Tycowski; C M Smith; Mei-Di Shu; Joan A Steitz
A small nucleolar RNA requirement for site-specific ribose methylation of rRNA in Xenopus.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(25):14480-5.
1996: W Y Tarn; Joan A Steitz
Highly diverged U4 and U6 small nuclear RNAs required for splicing rare AT-AC introns.
Science (New York, N.Y.) 1996;273(5283):1824-32.
1996: W Y Tarn; Joan A Steitz
A novel spliceosome containing U11, U12, and U5 snRNPs excises a minor class (AT-AC) intron in vitro.
Cell 1996;84(5):801-11.
1996: K T Tycowski; Mei-Di Shu; Joan A Steitz
A mammalian gene with introns instead of exons generating stable RNA products.
Nature 1996;379(6564):464-6.
1995: Joan A Steitz; K T Tycowski
Small RNA chaperones for ribosome biogenesis.
Science (New York, N.Y.) 1995;270(5242):1626-7.
1995: D C Cho; E C Scharl; Joan A Steitz
Decreasing the distance between the two conserved sequence elements of histone pre-messenger RNA interferes with 3' processing in vitro.
RNA (New York, N.Y.) 1995;1(9):905-14.
1995: W Y Tarn; T A Yario; Joan A Steitz
U12 snRNA in vertebrates: evolutionary conservation of 5' sequences implicated in splicing of pre-mRNAs containing a minor class of introns.
RNA (New York, N.Y.) 1995;1(6):644-56.
1995: Y Mishima; Joan A Steitz
Site-specific crosslinking of 4-thiouridine-modified human tRNA(3Lys) to reverse transcriptase from human immunodeficiency virus type I.
The EMBO journal 1995;14(11):2679-87.
1995: Vic Myer; Joan A Steitz
Isolation and characterization of a novel, low abundance hnRNP protein: A0.
RNA (New York, N.Y.) 1995;1(2):171-82.
1995: W Y Tarn; Joan A Steitz
Modulation of 5' splice site choice in pre-messenger RNA by two distinct steps.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(7):2504-8.
1994: K T Tycowski; Mei-Di Shu; Joan A Steitz
Requirement for intron-encoded U22 small nucleolar RNA in 18S ribosomal RNA maturation.
Science (New York, N.Y.) 1994;266(5190):1558-61.
1994: W Y Tarn; Joan A Steitz
SR proteins can compensate for the loss of U1 snRNP functions in vitro.
Genes & development 1994;8(22):2704-17.
1994: B A Peculis; Joan A Steitz
Sequence and structural elements critical for U8 snRNP function in Xenopus oocytes are evolutionarily conserved.
Genes & development 1994;8(18):2241-55.
1994: E C Scharl; Joan A Steitz
The site of 3' end formation of histone messenger RNA is a fixed distance from the downstream element recognized by the U7 snRNP.
The EMBO journal 1994;13(10):2432-40.
1994: D P Toczyski; A Gregory Matera; David C Ward; Joan A Steitz
The Epstein-Barr virus (EBV) small RNA EBER1 binds and relocalizes ribosomal protein L22 in EBV-infected human B lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(8):3463-7.
1993: Erik J Sontheimer; Joan A Steitz
The U5 and U6 small nuclear RNAs as active site components of the spliceosome.
Science (New York, N.Y.) 1993;262(5142):1989-96.
1993: J J Cortes; Erik J Sontheimer; S D Seiwert; Joan A Steitz
Mutations in the conserved loop of human U5 snRNA generate use of novel cryptic 5' splice sites in vivo.
The EMBO journal 1993;12(13):5181-9.
1993: D A Wassarman; Joan A Steitz
A base-pairing interaction between U2 and U6 small nuclear RNAs occurs in > 150S complexes in HeLa cell extracts: implications for the spliceosome assembly pathway.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(15):7139-43.
1993: Anita Gilliam; Joan A Steitz
Rare scleroderma autoantibodies to the U11 small nuclear ribonucleoprotein and to the trimethylguanosine cap of U small nuclear RNAs.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(14):6781-5.
1993: Thomas A Steitz; Joan A Steitz
A general two-metal-ion mechanism for catalytic RNA.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(14):6498-502.
1993: K T Tycowski; Mei-Di Shu; Joan A Steitz
A small nucleolar RNA is processed from an intron of the human gene encoding ribosomal protein S3.
Genes & development 1993;7(7A):1176-90.
1993: B A Peculis; Joan A Steitz
Disruption of U8 nucleolar snRNA inhibits 5.8S and 28S rRNA processing in the Xenopus oocyte.
Cell 1993;73(6):1233-45.
1993: S D Seiwert; Joan A Steitz
Uncoupling two functions of the U1 small nuclear ribonucleoprotein particle during in vitro splicing.
Molecular and cellular biology 1993;13(6):3135-45.
1993: K M Wassarman; Joan A Steitz
Association with terminal exons in pre-mRNAs: a new role for the U1 snRNP?
Genes & development 1993;7(4):647-59.
1993: D P Toczyski; Joan A Steitz
The cellular RNA-binding protein EAP recognizes a conserved stem-loop in the Epstein-Barr virus small RNA EBER 1.
Molecular and cellular biology 1993;13(1):703-10.
1992: J R Wyatt; Erik J Sontheimer; Joan A Steitz
Site-specific cross-linking of mammalian U5 snRNP to the 5' splice site before the first step of pre-mRNA splicing.
Genes & development 1992;6(12B):2542-53.
1992: K Tyc; Joan A Steitz
A new interaction between the mouse 5' external transcribed spacer of pre-rRNA and U3 snRNA detected by psoralen crosslinking.
Nucleic acids research 1992;20(20):5375-82.
1992: D A Wassarman; Joan A Steitz
Interactions of small nuclear RNA's with precursor messenger RNA during in vitro splicing.
Science (New York, N.Y.) 1992;257(5078):1918-25.
1992: Joan A Steitz
Splicing takes a holliday.
Science (New York, N.Y.) 1992;257(5072):888-9.
1992: K M Wassarman; Joan A Steitz
The low-abundance U11 and U12 small nuclear ribonucleoproteins (snRNPs) interact to form a two-snRNP complex.
Molecular and cellular biology 1992;12(3):1276-85.
1992: Vic Myer; S I Lee; Joan A Steitz
Viral small nuclear ribonucleoproteins bind a protein implicated in messenger RNA destabilization.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(4):1296-300.
1992: Erik J Sontheimer; Joan A Steitz
Three novel functional variants of human U5 small nuclear RNA.
Molecular and cellular biology 1992;12(2):734-46.
1991: Susan J. Baserga; X D Yang; Joan A Steitz
Three pseudogenes for human U13 snRNA belong to class III.
Gene 1991;107(2):347-8.
1991: U M Bond; T A Yario; Joan A Steitz
Multiple processing-defective mutations in a mammalian histone pre-mRNA are suppressed by compensatory changes in U7 RNA both in vivo and in vitro.
Genes & development 1991;5(9):1709-22.
1991: Susan J. Baserga; X D Yang; Joan A Steitz
An intact Box C sequence in the U3 snRNA is required for binding of fibrillarin, the protein common to the major family of nucleolar snRNPs.
The EMBO journal 1991;10(9):2645-51.
1991: D A Wassarman; Joan A Steitz
Structural analyses of the 7SK ribonucleoprotein (RNP), the most abundant human small RNP of unknown function.
Molecular and cellular biology 1991;11(7):3432-45.
1991: D P Toczyski; Joan A Steitz
EAP, a highly conserved cellular protein associated with Epstein-Barr virus small RNAs (EBERs).
The EMBO journal 1991;10(2):459-66.
1990: J P Bruzik; Joan A Steitz
Spliced leader RNA sequences can substitute for the essential 5' end of U1 RNA during splicing in a mammalian in vitro system.
Cell 1990;62(5):889-99.
1990: S I Lee; Joan A Steitz
Herpesvirus saimiri U RNAs are expressed and assembled into ribonucleoprotein particles in the absence of other viral genes.
Journal of virology 1990;64(8):3905-15.
1990: S Kass; K Tyc; Joan A Steitz; Barbara Sollner-Webb
The U3 small nucleolar ribonucleoprotein functions in the first step of preribosomal RNA processing.
Cell 1990;60(6):897-908.
1990: Joan A Steitz; J P Bruzik; K Tyc; S Kass; Barbara Sollner-Webb
Molecular analyses of the functions of SL and U3 snRNPs.
Molecular biology reports 1990;14(2-3):123.
1989: A L Pinto; Joan A Steitz
The mammalian analogue of the yeast PRP8 splicing protein is present in the U4/5/6 small nuclear ribonucleoprotein particle and the spliceosome.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(22):8742-6.
1989: K Tyc; Joan A Steitz
U3, U8 and U13 comprise a new class of mammalian snRNPs localized in the cell nucleolus.
The EMBO journal 1989;8(10):3113-9.
1989: K L Mowry; R Oh; Joan A Steitz
Each of the conserved sequence elements flanking the cleavage site of mammalian histone pre-mRNAs has a distinct role in the 3'-end processing reaction.
Molecular and cellular biology 1989;9(7):3105-8.
1989: E Gottlieb; Joan A Steitz
The RNA binding protein La influences both the accuracy and the efficiency of RNA polymerase III transcription in vitro.
The EMBO journal 1989;8(3):841-50.
1989: E Gottlieb; Joan A Steitz
Function of the mammalian La protein: evidence for its action in transcription termination by RNA polymerase III.
The EMBO journal 1989;8(3):851-61.
1989: David A Wassarman; S I Lee; Joan A Steitz
Nucleotide sequence of HSUR 5 RNA from herpesvirus saimiri.
Nucleic acids research 1989;17(3):1258.
1988: K A Montzka; Joan A Steitz
Additional low-abundance human small nuclear ribonucleoproteins: U11, U12, etc.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(23):8885-9.
1988: K A Parker; J P Bruzik; Joan A Steitz
An in vitro interaction between the human U3 snRNP and 28S rRNA sequences near the alpha-sarcin site.
Nucleic acids research 1988;16(22):10493-509.
1988: D H Kedes; Joan A Steitz
Correct in vivo splicing of the mouse immunoglobulin kappa light-chain pre-mRNA is dependent on 5' splice-site position even in the absence of transcription.
Genes & development 1988;2(11):1448-59.
1988: J P Bruzik; K Van Doren; D Hirsh; Joan A Steitz
Trans splicing involves a novel form of small nuclear ribonucleoprotein particles.
Nature 1988;335(6190):559-62.
1988: S I Lee; S C Murthy; J J Trimble; Ronald C Desrosiers; Joan A Steitz
Four novel U RNAs are encoded by a herpesvirus.
Cell 1988;54(5):599-607.
1988: Joan A Steitz; C Berg; J P Hendrick; H La Branche-Chabot; A Metspalu; J Rinke; T Yario
A 5S rRNA/L5 complex is a precursor to ribosome assembly in mammalian cells.
The Journal of cell biology 1988;106(3):545-56.
1988: J N Glickman; John G Howe; Joan A Steitz
Structural analyses of EBER1 and EBER2 ribonucleoprotein particles present in Epstein-Barr virus-infected cells.
Journal of virology 1988;62(3):902-11.
1987: K L Mowry; Joan A Steitz
Identification of the human U7 snRNP as one of several factors involved in the 3' end maturation of histone premessenger RNA's.
Science (New York, N.Y.) 1987;238(4834):1682-7.
1987: B E Rich; Joan A Steitz
Human acidic ribosomal phosphoproteins P0, P1, and P2: analysis of cDNA clones, in vitro synthesis, and assembly.
Molecular and cellular biology 1987;7(11):4065-74.
1987: D H Kedes; Joan A Steitz
Accurate 5' splice-site selection in mouse kappa immunoglobulin light chain premessenger RNAs is not cell-type-specific.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(22):7928-32.
1987: K A Parker; Joan A Steitz
Structural analysis of the human U3 ribonucleoprotein particle reveal a conserved sequence available for base pairing with pre-rRNA.
Molecular and cellular biology 1987;7(8):2899-913.
1984: I Pettersson; M Hinterberger; T Mimori; E Gottlieb; Joan A Steitz
The structure of mammalian small nuclear ribonucleoproteins. Identification of multiple protein components reactive with anti-(U1)ribonucleoprotein and anti-Sm autoantibodies.
The Journal of biological chemistry 1984;259(9):5907-14.
1984: T Mimori; M Hinterberger; I Pettersson; Joan A Steitz
Autoantibodies to the U2 small nuclear ribonucleoprotein in a patient with scleroderma-polymyositis overlap syndrome.
The Journal of biological chemistry 1984;259(1):560-5.
1983: Steve Mount; I Pettersson; M Hinterberger; A Karmas; Joan A Steitz
The U1 small nuclear RNA-protein complex selectively binds a 5' splice site in vitro.
Cell 1983;33(2):509-18.
1983: M Hinterberger; I Pettersson; Joan A Steitz
Isolation of small nuclear ribonucleoproteins containing U1, U2, U4, U5, and U6 RNAs.
The Journal of biological chemistry 1983;258(4):2604-13.
1983: M D Rosa; J P Hendrick; MR Lerner; Joan A Steitz; M Reichlin
A mammalian tRNAHis-containing antigen is recognized by the polymyositis-specific antibody anti-Jo-1.
Nucleic acids research 1983;11(3):853-70.
1983: Joan A Steitz; S L Wolin; J Rinke; I Pettersson; Steve Mount; E A Lerner; M Hinterberger; E Gottlieb
Small ribonucleoproteins from eukaryotes: structures and roles in RNA biogenesis.
Cold Spring Harbor symposia on quantitative biology 1983;47 Pt 2():893-900.
1982: Joan A Steitz; C Berg; E Gottlieb; John Hardin; C Hashimoto; J P Hendrick; M Hinterberger; M Krikeles; M R Lerner; Steve Mount
Structure and function of small ribonucleoproteins from eukaryotic cells.
Princess Takamatsu symposia 1982;12():101-7.
1981: J P Hendrick; S L Wolin; J Rinke; M R Lerner; Joan A Steitz
Ro small cytoplasmic ribonucleoproteins are a subclass of La ribonucleoproteins: further characterization of the Ro and La small ribonucleoproteins from uninfected mammalian cells.
Molecular and cellular biology 1981;1(12):1138-49.
1981: M D Rosa; E Gottlieb; MR Lerner; Joan A Steitz
Striking similarities are exhibited by two small Epstein-Barr virus-encoded ribonucleic acids and the adenovirus-associated ribonucleic acids VAI and VAII.
Molecular and cellular biology 1981;1(9):785-96.
1980: M R Lerner; J A Boyle; Steve Mount; S L Wolin; Joan A Steitz
Are snRNPs involved in splicing?
Nature 1980;283(5743):220-4.