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Irina Stepanov

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Aleksandar Knezevich; John Muzic; Dorothy K Hatsukami; Stephen S Hecht; Irina Stepanov
Nornicotine nitrosation in saliva and its relation to endogenous synthesis of N'-nitrosonornicotine in humans.
Irina Stepanov; Lois Biener; Robin L Bliss; Stephen S Hecht; Joni Jensen; Dorothy K Hatsukami
Increased pouch sizes and resulting changes in the amounts of nicotine and tobacco-specific N-nitrosamines in single pouches of Camel Snus and Marlboro Snus.
Irina Stepanov; Lois Biener; RL Bliss; Stephen S Hecht; Joni Jensen; Aleksandar Knezevich; Amy L Nyman; Dorothy K Hatsukami
Monitoring tobacco-specific N-nitrosamines and nicotine in novel Marlboro and Camel smokeless tobacco products: findings from Round 1 of the New Product Watch.

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All Publications

2013: Aleksandar Knezevich; John Muzic; Dorothy K Hatsukami; Stephen S Hecht; Irina Stepanov
Nornicotine nitrosation in saliva and its relation to endogenous synthesis of N'-nitrosonornicotine in humans.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2013;15(2):591-5.
2012: Irina Stepanov; Lois Biener; Robin L Bliss; Stephen S Hecht; Joni Jensen; Dorothy K Hatsukami
Increased pouch sizes and resulting changes in the amounts of nicotine and tobacco-specific N-nitrosamines in single pouches of Camel Snus and Marlboro Snus.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2012;14(10):1241-5.
2012: Irina Stepanov; Lois Biener; RL Bliss; Stephen S Hecht; Joni Jensen; Aleksandar Knezevich; Amy L Nyman; Dorothy K Hatsukami
Monitoring tobacco-specific N-nitrosamines and nicotine in novel Marlboro and Camel smokeless tobacco products: findings from Round 1 of the New Product Watch.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2012;14(3):274-81.
2011: Stephen S Hecht; Irina Stepanov; Dorothy K Hatsukami
Major tobacco companies have technology to reduce carcinogen levels but do not apply it to popular smokeless tobacco products.
Tobacco control 2011;20(6):443.
2011: Rachel I Vogel; Irina Stepanov; Steven G Carmella; Dorothy K Hatsukami; Stephen S Hecht
The ratio of a urinary tobacco-specific lung carcinogen metabolite to cotinine is significantly higher in passive than in active smokers.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2011;16(6):491-7.
2011: Jian-Min Yuan; Renwei Wang; Yu-Tang Gao; Stephen S Hecht; Aleksandar D Knezevich; Irina Stepanov
Urinary levels of the tobacco-specific carcinogen N'-nitrosonornicotine and its glucuronide are strongly associated with esophageal cancer risk in smokers.
Carcinogenesis 2011;32(9):1366-71.
2011: Michael Kotlyar; Louise A Hertsgaard; Bruce R Lindgren; Joni A Jensen; Steven G Carmella; Irina Stepanov; Sharon E Murphy; Stephen S Hecht; Dorothy K Hatsukami
Effect of oral snus and medicinal nicotine in smokers on toxicant exposure and withdrawal symptoms: a feasibility study.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2011;20(1):91-100.
2010: Dorothy K Hatsukami; Michael Kotlyar; Louise A Hertsgaard; Yan Zhang; Steven G Carmella; Joni A Jensen; Sharon S Allen; Peter G Shields; Sharon E Murphy; Irina Stepanov; Stephen S Hecht
Reduced nicotine content cigarettes: effects on toxicant exposure, dependence and cessation.
Addiction (Abingdon, England) 2010;105(2):343-55.
2010: Irina Stepanov; Peter W Villalta; Aleksandar Knezevich; Joni Jensen; Dorothy Hatsukami; Stephen S Hecht
Analysis of 23 polycyclic aromatic hydrocarbons in smokeless tobacco by gas chromatography-mass spectrometry.
Chemical research in toxicology 2010;23(1):66-73.
2009: Irina Stepanov; Steven G Carmella; Anna Briggs; Louise Hertsgaard; Bruce Lindgren; Dorothy Hatsukami; Stephen S Hecht
Presence of the carcinogen N'-nitrosonornicotine in the urine of some users of oral nicotine replacement therapy products.
Cancer research 2009;69(21):8236-40.
2009: Irina Stepanov; Stephen S Hecht
Mitochondrial DNA adducts in the lung and liver of F344 rats chronically treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and (S)-4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.
Chemical research in toxicology 2009;22(2):406-14.
2009: Irina Stepanov; Steven G Carmella; Shaomei Han; Angela Pinto; Andrew A Strasser; Caryn Lerman; Stephen S Hecht
Evidence for endogenous formation of N'-nitrosonornicotine in some long-term nicotine patch users.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2009;11(1):99-105.
2008: Irina Stepanov; Joni Jensen; Dorothy Hatsukami; Stephen S Hecht
New and traditional smokeless tobacco: comparison of toxicant and carcinogen levels.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2008;10(12):1773-82.
2008: Irina Stepanov; Pramod Upadhyaya; Steven G Carmella; Rachel M Feuer; Joni Jensen; Dorothy K Hatsukami; Stephen S Hecht
Extensive metabolic activation of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in smokers.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2008;17(7):1764-73.
2008: Irina Stepanov; Stephen S Hecht
Detection and quantitation of N'-nitrosonornicotine in human toenails by liquid chromatography-electrospray ionization-tandem mass spectrometry.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2008;17(4):945-8.
2008: Stephen S Hecht; Steven G Carmella; A Edmonds; Sharon E Murphy; Irina Stepanov; X Luo; Dorothy K Hatsukami
Exposure to nicotine and a tobacco-specific carcinogen increase with duration of use of smokeless tobacco.
Tobacco control 2008;17(2):128-31.
2008: Stephen S Hecht; Steven G Carmella; Irina Stepanov; Joni Jensen; Amanda Anderson; Dorothy K Hatsukami
Metabolism of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone to its biomarker total NNAL in smokeless tobacco users.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2008;17(3):732-5.
2007: Diana Porubin; Stephen S Hecht; Zhong-ze Li; Maria Gonta; Irina Stepanov
Endogenous formation of N'-nitrosonornicotine in F344 rats in the presence of some antioxidants and grape seed extract.
Journal of agricultural and food chemistry 2007;55(17):7199-204.
2007: Irina Stepanov; Stephen S Hecht; Bruce Lindgren; Peyton Jacob; Margaret Wilson; Neal L Benowitz
Relationship of human toenail nicotine, cotinine, and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol to levels of these biomarkers in plasma and urine.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007;16(7):1382-6.
2006: Irina Stepanov; Rachel M Feuer; Joni Jensen; Dorothy Hatsukami; Stephen S Hecht
Mass spectrometric quantitation of nicotine, cotinine, and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in human toenails.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2006;15(12):2378-83.
2006: Irina Stepanov; Joni Jensen; Dorothy Hatsukami; Stephen S Hecht
Tobacco-specific nitrosamines in new tobacco products.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2006;8(2):309-13.
2006: Irina Stepanov; Stephen S Hecht; Gheorghe Duca; Igor Mardari
Uptake of the tobacco-specific lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by Moldovan children.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2006;15(1):7-11.
2005: Irina Stepanov; Stephen S Hecht; Sidney S Mirvish; Maria Gonta
Comparative analysis of tobacco-specific nitrosamines and total N-nitroso compounds in moldovan cigarette tobacco.
Journal of agricultural and food chemistry 2005;53(20):8082-6.
2005: Irina Stepanov; Stephen S Hecht; Sreevidya Ramakrishnan; Prakash C Gupta
Tobacco-specific nitrosamines in smokeless tobacco products marketed in India.
International journal of cancer. Journal international du cancer 2005;116(1):16-9.
2005: Irina Stepanov; Stephen S Hecht
Tobacco-specific nitrosamines and their pyridine-N-glucuronides in the urine of smokers and smokeless tobacco users.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(4):885-91.
2002: Irina Stepanov; Steven G Carmella; Stephen S Hecht; Gheorghe Duca
Analysis of tobacco-specific nitrosamines in Moldovan cigarette tobacco.
Journal of agricultural and food chemistry 2002;50(10):2793-7.