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Katherine Stephenson

Research Profile

Chemicals & Drugs

Living Beings

Physiology

Anatomy

Disorders

Liver Neoplasms

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Publications

TOP 3
Young-Hoon Ahn; You Sang Hwang; Hua Liu; Xiu Jun Wang; Ying Zhang; Katherine K Stephenson; Tatiana N Boronina; Robert N Cole; Albena T Dinkova-Kostova; Paul Talalay; Philip A Cole
Electrophilic tuning of the chemoprotective natural product sulforaphane.
Lawrence Lee; Katherine K Stephenson; Jed W Fahey; Teresa Parsons; Paul S Lietman; Adriana S A Andrade; Xiaoguang Lei; Heedong Yun; Gaik H Soon; Ping Shen; Samuel J Danishefsky; Charles Flexner
Induction of chemoprotective phase 2 enzymes by ginseng and its components.
Karen Liby; Mark M Yore; Bill D Roebuck; Karen J Baumgartner; Tadashi Honda; Chitra Sundararajan; Hidenori Yoshizawa; Gordon W Gribble; Charlotte R Williams; Renee Risingsong; Darlene B Royce; Albena T Dinkova-Kostova; Katherine K Stephenson; Patricia A Egner; Melinda S Yates; John Groopman; Thomas W Kensler; Michael B. Sporn
A novel acetylenic tricyclic bis-(cyano enone) potently induces phase 2 cytoprotective pathways and blocks liver carcinogenesis induced by aflatoxin.

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All Publications

2010: Young-Hoon Ahn; You Sang Hwang; Hua Liu; Xiu Jun Wang; Ying Zhang; Katherine K Stephenson; Tatiana N Boronina; Robert N Cole; Albena T Dinkova-Kostova; Paul Talalay; Philip A Cole
Electrophilic tuning of the chemoprotective natural product sulforaphane.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(21):9590-5.
2009: Lawrence Lee; Katherine K Stephenson; Jed W Fahey; Teresa Parsons; Paul S Lietman; Adriana S A Andrade; Xiaoguang Lei; Heedong Yun; Gaik H Soon; Ping Shen; Samuel J Danishefsky; Charles Flexner
Induction of chemoprotective phase 2 enzymes by ginseng and its components.
Planta medica 2009;75(10):1129-33.
2008: Karen Liby; Mark M Yore; Bill D Roebuck; Karen J Baumgartner; Tadashi Honda; Chitra Sundararajan; Hidenori Yoshizawa; Gordon W Gribble; Charlotte R Williams; Renee Risingsong; Darlene B Royce; Albena T Dinkova-Kostova; Katherine K Stephenson; Patricia A Egner; Melinda S Yates; John Groopman; Thomas W Kensler; Michael B. Sporn
A novel acetylenic tricyclic bis-(cyano enone) potently induces phase 2 cytoprotective pathways and blocks liver carcinogenesis induced by aflatoxin.
Cancer research 2008;68(16):6727-33.
2008: Albena T Dinkova-Kostova; Stephanie N Jenkins; Scott L Wehage; David L Huso; Andrea L Benedict; Katherine K Stephenson; Jed W Fahey; Hua Liu; Karen T Liby; Tadashi Honda; Gordon W Gribble; Michael B. Sporn; Paul Talalay
A dicyanotriterpenoid induces cytoprotective enzymes and reduces multiplicity of skin tumors in UV-irradiated mice.
Biochemical and biophysical research communications 2008;367(4):859-65.
2007: Karen T Liby; Tadashi Honda; Charlotte R Williams; Renee Risingsong; Darlene B Royce; Nanjoo Suh; Albena T Dinkova-Kostova; Katherine K Stephenson; Paul Talalay; Chitra Sundararajan; Gordon W Gribble; Michael B. Sporn
Novel semisynthetic analogues of betulinic acid with diverse cytoprotective, antiproliferative, and proapoptotic activities.
Molecular cancer therapeutics 2007;6(7):2113-9.
2006: Albena T Dinkova-Kostova; Stephanie N Jenkins; Jed W Fahey; Lingxiang Ye; Scott L Wehage; Karen T Liby; Katherine K Stephenson; Kristina L Wade; Paul Talalay
Protection against UV-light-induced skin carcinogenesis in SKH-1 high-risk mice by sulforaphane-containing broccoli sprout extracts.
Cancer letters 2006;240(2):243-52.
2006: Li Tang; Yuesheng Zhang; Hillary E Jobson; Jun Li; Katherine K Stephenson; Kristina L Wade; Jed W Fahey
Potent activation of mitochondria-mediated apoptosis and arrest in S and M phases of cancer cells by a broccoli sprout extract.
Molecular cancer therapeutics 2006;5(4):935-44.
2006: Theresa A Shapiro; Jed W Fahey; Albena T Dinkova-Kostova; W David Holtzclaw; Katherine K Stephenson; Kristina L Wade; Lingxiang Ye; Paul Talalay
Safety, tolerance, and metabolism of broccoli sprout glucosinolates and isothiocyanates: a clinical phase I study.
Nutrition and cancer 2006;55(1):53-62.
2006: Rex Munday; Yuesheng Zhang; Jed W Fahey; Hillary E Jobson; Christine M Munday; Jun Li; Katherine K Stephenson
Evaluation of isothiocyanates as potent inducers of carcinogen-detoxifying enzymes in the urinary bladder: critical nature of in vivo bioassay.
Nutrition and cancer 2006;54(2):223-31.
2005: Thomas W Kensler; Jian-Guo Chen; Patricia A Egner; Jed W Fahey; Lisa P Jacobson; Katherine K Stephenson; Lingxiang Ye; Jamie L Coady; Jin-Bing Wang; Yan Wu; Yan Sun; Qi-Nan Zhang; Bao-Chu Zhang; Yuan-Rong Zhu; Geng-Sun Qian; Stephen G Carmella; Stephen S Hecht; Lorie Benning; Stephen J Gange; John Groopman; Paul Talalay
Effects of glucosinolate-rich broccoli sprouts on urinary levels of aflatoxin-DNA adducts and phenanthrene tetraols in a randomized clinical trial in He Zuo township, Qidong, People's Republic of China.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(11 Pt 1):2605-13.
2005: Jed W Fahey; Katherine K Stephenson; Albena T Dinkova-Kostova; Patricia A Egner; Thomas W Kensler; Paul Talalay
Chlorophyll, chlorophyllin and related tetrapyrroles are significant inducers of mammalian phase 2 cytoprotective genes.
Carcinogenesis 2005;26(7):1247-55.
2005: Albena T Dinkova-Kostova; Karen T Liby; Katherine K Stephenson; W David Holtzclaw; Xiangqun Gao; Nanjoo Suh; Charlotte Williams; Renee Risingsong; Tadashi Honda; Gordon W Gribble; Michael B. Sporn; Paul Talalay
Extremely potent triterpenoid inducers of the phase 2 response: correlations of protection against oxidant and inflammatory stress.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(12):4584-9.
2004: Jed W Fahey; Albena T Dinkova-Kostova; Katherine K Stephenson; Paul Talalay
The "Prochaska" microtiter plate bioassay for inducers of NQO1.
Methods in enzymology 2004;382():243-58.
2003: Jed W Fahey; Kristina L Wade; Katherine K Stephenson; F Edward Chou
Separation and purification of glucosinolates from crude plant homogenates by high-speed counter-current chromatography.
Journal of chromatography. A 2003;996(1-2):85-93.
2002: Jed W Fahey; Katherine K Stephenson
Pinostrobin from honey and Thai ginger (Boesenbergia pandurata): a potent flavonoid inducer of mammalian phase 2 chemoprotective and antioxidant enzymes.
Journal of agricultural and food chemistry 2002;50(25):7472-6.
2002: Fernanda Maria Valente Pereira; Eduardo Rosa; Jed W Fahey; Katherine K Stephenson; Rosa Carvalho; Alfredo Aires
Influence of temperature and ontogeny on the levels of glucosinolates in broccoli (Brassica oleracea Var. italica) sprouts and their effect on the induction of mammalian phase 2 enzymes.
Journal of agricultural and food chemistry 2002;50(21):6239-44.
2002: Jed W Fahey; Xavier Haristoy; Patrick Dolan; Thomas W Kensler; Isabelle Scholtus; Katherine K Stephenson; Paul Talalay; Alain Lozniewski
Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and prevents benzo[a]pyrene-induced stomach tumors.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(11):7610-5.
2001: J K Troyer; Katherine K Stephenson; Jed W Fahey
Analysis of glucosinolates from broccoli and other cruciferous vegetables by hydrophilic interaction liquid chromatography.
Journal of chromatography. A 2001;919(2):299-304.
2001: Jay H Fowke; Jed W Fahey; Katherine K Stephenson; James R Hebert
Using isothiocyanate excretion as a biological marker of Brassica vegetable consumption in epidemiological studies: evaluating the sources of variability.
Public health nutrition 2001;4(3):837-46.
2001: Theresa A Shapiro; Jed W Fahey; Kristina L Wade; Katherine K Stephenson; Paul Talalay
Chemoprotective glucosinolates and isothiocyanates of broccoli sprouts: metabolism and excretion in humans.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2001;10(5):501-8.
1998: Theresa A Shapiro; Jed W Fahey; Kristina L Wade; Katherine K Stephenson; Paul Talalay
Human metabolism and excretion of cancer chemoprotective glucosinolates and isothiocyanates of cruciferous vegetables.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1998;7(12):1091-100.