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Stanislaw Stepkowski

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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T-Lymphocytes

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Co-Publications
Name
98
Kahan, Barry
33
Wang, Mou-Er
28
Wang, Min
27
Tian, Ling
23
Kirken, Robert
17
Qu, Xuimei
16
Yu, J
13
Bennett, Frank
11
Tejpal, Neelam
10
Nagy, Zsuzsanna
9
Napoli, Kimberly
9
Condon, Tom
9
Stecker, Kim
9
Taegtmeyer, Heinrich
8
Chen, Wenhau

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Publications

TOP 3
Khattar Mithun; Chen Wenhao; Stepkowski Stanislaw M
Expanding and converting regulatory T cells: a horizon for immunotherapy.
Stepkowski Stanislaw M
Targeting of the fifth complement (C5) component to fight graft impairment after ischemia-reperfusion injury.
Wenderfer Scott E; Stepkowski Stanislaw M; Braun Michael C
Increased survival and reduced renal injury in MRL/lpr mice treated with a novel sphingosine-1-phosphate receptor agonist.

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All Publications

2009: Khattar Mithun; Chen Wenhao; Stepkowski Stanislaw M
Expanding and converting regulatory T cells: a horizon for immunotherapy.
Archivum immunologiae et therapiae experimentalis 2009;57(3):199-204.
2008: Stepkowski Stanislaw M
Targeting of the fifth complement (C5) component to fight graft impairment after ischemia-reperfusion injury.
Transplantation 2008;86(10):1351.
2008: Wenderfer Scott E; Stepkowski Stanislaw M; Braun Michael C
Increased survival and reduced renal injury in MRL/lpr mice treated with a novel sphingosine-1-phosphate receptor agonist.
Kidney international 2008;74(10):1319-26.
2008: Stepkowski Stanislaw M; Chen Wenhao; Ross Jeremy A; Nagy Zsuzsanna S; Kirken Robert A
STAT3: an important regulator of multiple cytokine functions.
Transplantation 2008;85(10):1372-7.
2007: Chen Wenhao; Diao Jun; Stepkowski Stanislaw M; Zhang Li
Both infiltrating regulatory T cells and insufficient antigen presentation are involved in long-term cardiac xenograft survival.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(3):1542-8.
2007: Ross Jeremy A; Nagy Zsuzsanna S; Cheng Hanyin; Stepkowski Stanislaw M; Kirken Robert A
Regulation of T cell homeostasis by JAKs and STATs.
Archivum immunologiae et therapiae experimentalis 2007;55(4):231-45.
2007: Razeghi Peter; Wang Mou-Er; Youker Keith A; Golfman Leonard; Stepkowski Stanislaw; Taegtmeyer Heinrich
Lack of NF-kappaB1 (p105/p50) attenuates unloading-induced downregulation of PPARalpha and PPARalpha-regulated gene expression in rodent heart.
Cardiovascular research 2007;74(1):133-9.
2007: Razeghi Peter; Volpini Kaelin C; Wang Mou-Er; Youker Keith A; Stepkowski Stanislaw; Taegtmeyer Heinrich
Mechanical unloading of the heart activates the calpain system.
Journal of molecular and cellular cardiology 2007;42(2):449-52.
2006: Stepkowski Stanislaw M; Phan Tammy; Zhang Huimin; Bilinski Szczepan; Kloc Malgorzata; Qi Yuhua; Katz Stephen M; Rutzky Lynne P
Immature syngeneic dendritic cells potentiate tolerance to pancreatic islet allografts depleted of donor dendritic cells in microgravity culture condition.
Transplantation 2006;82(12):1756-63.
2006: Nagy Zsuzsanna S; Rui Hallgeir; Stepkowski Stanislaw M; Karras James; Kirken Robert A
A preferential role for STAT5, not constitutively active STAT3, in promoting survival of a human lymphoid tumor.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(8):5032-40.
2006: Stepkowski Stanislaw M; Kirken Robert A
Janus tyrosine kinases and signal transducers and activators of transcription regulate critical functions of T cells in allograft rejection and transplantation tolerance.
Transplantation 2006;82(3):295-303.
2006: Razeghi Peter; Buksinska-Lisik Malgorzata; Palanichamy Nanthini; Stepkowski Stanislaw; Frazier O Howard; Taegtmeyer Heinrich
Transcriptional regulators of ribosomal biogenesis are increased in the unloaded heart.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(8):1090-6.
2006: Razeghi Peter; Baskin Kedryn K; Sharma Saumya; Young Martin E; Stepkowski Stanislaw; Essop M Faadiel; Taegtmeyer Heinrich
Atrophy, hypertrophy, and hypoxemia induce transcriptional regulators of the ubiquitin proteasome system in the rat heart.
Biochemical and biophysical research communications 2006;342(2):361-4.
2006: Zhang Ye; Kirken Robert A; Furian Lucrezia; Janczewska Slawa; Qu Xiumei; Hancock Wayne W; Wang Mouer; Tejpal Neelam; Kerman Ronald; Kahan Barry D; Stepkowski Stanislaw M
Allograft rejection requires STAT5a/b-regulated antiapoptotic activity in T cells but not B cells.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(1):128-37.
2006: Sharma Saumya; Ying Jun; Razeghi Peter; Stepkowski Stanislaw; Taegtmeyer Heinrich
Atrophic remodeling of the transplanted rat heart.
Cardiology 2006;105(2):128-36.
2005: Hong M E; Hong J C; Stepkowski S; Kahan B D
Correlation between cyclosporine-induced nephrotoxicity in reduced nephron mass and expression of kidney injury molecule-1 and aquaporin-2 gene.
Transplantation proceedings 2005;37(10):4254-8.
2005: Semiletova Natalya V; Shen Xiu-Da; Baibakov Boris; Feldman Daniel M; Mukherjee Kaushik; Frank Jonathan M; Stepkowski Stainslaw M; Busuttil Ronald W; Kupiec-Weglinski Jerzy W; Ghobrial Rafik M
Inhibition of chronic rejection by antibody induced vascular accommodation in fully allogeneic heart allografts.
Transplantation 2005;80(11):1535-40.
2005: Stepkowski Stanislaw M; Kao Judy; Wang Mou-Er; Tejpal Neelam; Podder Hemangshu; Furian Lucrezia; Dimmock Jonathan; Jha Amitabh; Das Umashankar; Kahan Barry D; Kirken Robert A
The Mannich base NC1153 promotes long-term allograft survival and spares the recipient from multiple toxicities.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(7):4236-46.
2005: Chen Wenhau; Langer Robert M; Janczewska Slawa; Furian Lucrezia; Geary Richard; Qu Xuimei; Wang Mouer; Verani Regina; Condon Tom; Stecker Kim; Bennett C Frank; Stepkowski Stanislaw M
Methoxyethyl-modified intercellular adhesion molecule-1 antisense phosphorothiateoligonucleotides inhibit allograft rejection, ischemic-reperfusion injury, and cyclosporine-induced nephrotoxicity.
Transplantation 2005;79(4):401-8.
2005: Stepkowski Stanislaw M; Knight Richard; Podder Hemangshu; Kerman Ronald
Our picks of big and not so big issues.
Annals of transplantation : quarterly of the Polish Transplantation Society 2005;10(3):37-40.
2004: Langer Robert; Wang Mouer; Stepkowski Stanislaw M; Hancock Wayne W; Han Rongxiang; Li Ping; Feng Lily; Kirken Robert A; Berens Kurt L; Dupre Brian; Podder Hemangshu; Dixon Richard A F; Kahan Barry D
Selectin inhibitor bimosiamose prolongs survival of kidney allografts by reduction in intragraft production of cytokines and chemokines.
Journal of the American Society of Nephrology : JASN 2004;15(11):2893-901.
2004: Kahan Barry D; Stepkowski Stanislaw; Kilic Murat; Katz Steven M; Van Buren Charles T; Welsh Maria S; Tami Joseph A; Shanahan William R
Phase I and phase II safety and efficacy trial of intercellular adhesion molecule-1 antisense oligodeoxynucleotide (ISIS 2302) for the prevention of acute allograft rejection.
Transplantation 2004;78(6):858-63.
2004: Bai Shuang; Stepkowski Stanislaw M; Kahan Barry D; Brunner Lane J
Metabolic interaction between cyclosporine and sirolimus.
Transplantation 2004;77(10):1507-12.
2004: Nagy Zsuzsanna S; Ross Jeremy; Cheng Hanyin; Stepkowski Stanislaw M; Kirken Robert A
Regulation of lymphoid cell apoptosis by Jaks and Stats.
Critical reviews in immunology 2004;24(2):87-110.
2003: Razeghi Peter; Sharma Saumya; Ying Jun; Li Yi-Ping; Stepkowski Stanislaw; Reid Michael B; Taegtmeyer Heinrich
Atrophic remodeling of the heart in vivo simultaneously activates pathways of protein synthesis and degradation.
Circulation 2003;108(20):2536-41.
2003: Perez John; Stepkowski Stanislaw M; Song Ping; Trawick Barton; Wang Mou-Er; Janczewska Slawa; Kahan Barry D
Selection of lowly immunogenic and highly tolerogenic donor and recipient allochimeric class I major histocompatibility complex proteins.
Transplantation 2003;76(8):1201-7.
2003: Behbod Fariba; Nagy Zsuzsanna S; Stepkowski Stanislaw M; Karras James; Johnson Charlene R; Jarvis W David; Kirken Robert A
Specific inhibition of Stat5a/b promotes apoptosis of IL-2-responsive primary and tumor-derived lymphoid cells.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(8):3919-27.
2003: Kahan B D; Kirken R A; Stepkowski S M
New approaches to transplant immunosuppression.
Transplantation proceedings 2003;35(5):1621-3.
2003: Stepkowski S M
Preclinical results of sirolimus treatment in transplant models.
Transplantation proceedings 2003;35(3 Suppl):219S-226S.
2003: Janczewska Slawa; Wisniewski Marcin; Stepkowski Stanislaw M; Lukomska Barbara
Fast hematopoietic recovery after bone marrow engraftment needs physiological proximity of stromal and stem cells.
Cell transplantation 2003;12(4):399-406.
2002: Nagy Zsuzsanna S; Wang Yuling; Erwin-Cohen Rebecca A; Aradi János; Monia Brett; Wang Li Hua; Stepkowski Stanislaw M; Rui Hallgeir; Kirken Robert A
Interleukin-2 family cytokines stimulate phosphorylation of the Pro-Ser-Pro motif of Stat5 transcription factors in human T cells: resistance to suppression of multiple serine kinase pathways.
Journal of leukocyte biology 2002;72(4):819-28.
2002: Rutzky Lynne P; Bilinski Szczepan; Kloc Malgorzata; Phan Tammy; Zhang Huimin; Katz Stephen M; Stepkowski Stanislaw M
Microgravity culture condition reduces immunogenicity and improves function of pancreatic islets1.
Transplantation 2002;74(1):13-21.
2002: Stepkowski Stanislaw M; Kirken Robert A; Trawick Barton W; Wang Min; Tejpal Neelam; Wang Mou-Er; Tian Ling; Clark James; Kahan Barry D
Allochimeric class I MHC protein-induced tolerance by partial TCR engagement requires activation of both CTL4- and common gamma-chain-dependent cytokine signals.
Transplantation 2002;73(8):1227-35.
2002: Stepkowski Stanislaw M; Erwin-Cohen Rebecca A; Behbod Fariba; Wang Mou-Er; Qu Xienui; Tejpal Neelam; Nagy Zsuzsanna S; Kahan Barry D; Kirken Robert A
Selective inhibitor of Janus tyrosine kinase 3, PNU156804, prolongs allograft survival and acts synergistically with cyclosporine but additively with rapamycin.
Blood 2002;99(2):680-9.
2001: Stepkowski S M; Kirken R A; Nagy Z S; Trawick B W; Wang M; Tejpal N; Wang M E; Tian L; Clark J; Kahan B D
The role of Stat5 in the induction of regulatory T cells in transplantation tolerance.
Transplantation proceedings 2001;33(7-8):3835-6.
2001: Stepkowski S M; Nagy Z S; Kahan B D; Kirken R A
The role of signals 1, 2, and 3 in induction of transplantation tolerance.
Transplantation proceedings 2001;33(7-8):3831-2.
2001: Stepkowski S M; Chen W; Bennett C F; Condon T P; Stecker K; Tian L; Kahan B D
Phosphorothioate/methoxyethyl-modified ICAM-1 antisense oligonucleotides improves prevention of ischemic/reperfusion injury.
Transplantation proceedings 2001;33(7-8):3705-6.
2001: Stepkowski S M; Nagy Z S; Wang M E; Behbod F; Erwin-Cohen R; Kahan B D; Kirken R A
PNU156804 inhibits Jak3 tyrosine kinase and rat heart allograft rejection.
Transplantation proceedings 2001;33(7-8):3272-3.
2001: Stepkowski S M; Chen W; Geary R; Wang M E; Condon T; Stecker K; Bennett C F
An oral formulation for intracellular adhesion molecules-1 antisense oligonucleotides.
Transplantation proceedings 2001;33(7-8):3271.
2001: Stepkowski S M
The role of adhesion molecules and chemokines in homeostasis and pathologic processes in transplanted organs.
Transplantation proceedings 2001;33(7-8):3064-6.
2001: Qu X; Kirken R A; Tian L; Wang M; Bennett C F; Stepkowski S M
Selective inhibition of IL-2 gene expression by IL-2 antisense oligonucleotides blocks heart allograft rejection.
Transplantation 2001;72(5):915-23.
2001: Doenst T; Goodwin G W; Cedars A M; Wang M; Stepkowski S; Taegtmeyer H
Load-induced changes in vivo alter substrate fluxes and insulin responsiveness of rat heart in vitro.
Metabolism: clinical and experimental 2001;50(9):1083-90.
2001: Bai S; Brunner L J; Stepkowski S M; Napoli K L; Kahan B D
Effect of low dose cyclosporine and sirolimus on hepatic drug metabolism in the rat1.
Transplantation 2001;71(11):1585-92.
2001: Podder H; Stepkowski S M; Napoli K L; Clark J; Verani R R; Chou T C; Kahan B D
Pharmacokinetic interactions augment toxicities of sirolimus/cyclosporine combinations.
Journal of the American Society of Nephrology : JASN 2001;12(5):1059-71.
2001: Young M E; Patil S; Ying J; Depre C; Ahuja H S; Shipley G L; Stepkowski S M; Davies P J; Taegtmeyer H
Uncoupling protein 3 transcription is regulated by peroxisome proliferator-activated receptor (alpha) in the adult rodent heart.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(3):833-45.
2001: Behbod F; Erwin-Cohen R A; Wang M E; Trawick B W; Qu X; Verani R; Kahan B D; Stepkowski S M; Kirken R A
Concomitant inhibition of Janus kinase 3 and calcineurin-dependent signaling pathways synergistically prolongs the survival of rat heart allografts.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(6):3724-32.
2001: Podder H; Stepkowski S M; Napoli K; Kahan B D
Pharmacokinetic interactions between sirolimus and cyclosporine exacerbate renal dysfunction.
Transplantation proceedings 2001;33(1-2):1086.
2001: Chen W; Bennett C F; Condon T P; Stecker K; Tian L; Kahan B D; Stepkowski S M
Methoxyethyl modification of phosphorothioate ICAM-1 antisense oligonucleotides improves prevention of ischemic/reperfusion injury.
Transplantation proceedings 2001;33(1-2):854.
2001: Ghobrial R; Amersi F; Stecker K; Kato H; Melinek J; Singer J; Mhoyan A; Busuttil R W; Kupiec-Weglinski J W; Stepkowski S M
Amelioration of hepatic ischemia/reperfusion injury with intercellular adhesion molecule-1 antisense oligodeoxynucleotides.
Transplantation proceedings 2001;33(1-2):538.
2001: Rutzky L; Kloc M; Bilinski S; Phan T; Zhang H; Stepkowski S M; Katz S
Microgravity culture conditions decrease immunogenicity but maintain excellent morphology of pancreatic islets.
Transplantation proceedings 2001;33(1-2):388.
2001: Stepkowski S M; Chen W; Geary R; Wang M E; Condon T; Stecker K; Bennett C F
Development of an oral formulation for ICAM-1 antisense oligonucleotides.
Transplantation proceedings 2001;33(1-2):387.
2001: Tian L; Qu X; Wang M E; Kirken R A; Bennett F C; Stepkowski S M
Selective inhibition of IL-2 mRNA blocks allograft rejection by limiting T cell clonal expansion.
Transplantation proceedings 2001;33(1-2):330.
2001: Wang M; Kirken R; Behbod F; Erwin-Cohen R; Stepkowski S M; Kahan B D
Inhibition of Jak3 tyrosine kinase by PNU156804 blocks rat heart allograft rejection.
Transplantation proceedings 2001;33(1-2):201.
2001: Stepkowski S M; Kirken R A; Wang M; Yu J; Akioka K; Kahan B D
Tolerance induction by alteration of T cell receptor (TCR) signaling using an allochimeric donor/recipient class I MHC protein.
Transplantation proceedings 2001;33(1-2):131.
2001: Kirken R A; Erwin-Cohen R; Behbod F; Wang M; Stepkowski S M; Kahan B D
Tyrphostin AG490 selectively inhibits activation of the JAK3/STAT5/MAPK pathway and rejection of rat heart allografts.
Transplantation proceedings 2001;33(1-2):95.
2000: Katz S M; Bennett F; Stecker K; Clark J H; Pham T; Wang M E; Kahan B D; Stepkowski S M
ICAM-1 antisense oligodeoxynucleotide improves islet allograft survival and function.
Cell transplantation 2000;9(6):817-28.
2000: Okamoto M; Stepkowski S M; Wang M; Kahan B D
Use of allochimeric proteins to mitigate graft-versus-host and host-versus-graft immune responses to rat small bowel allografts.
Transplantation 2000;70(7):1060-7.
2000: Stepkowski S M; Qu X; Wang M E; Tian L; Chen W; Wancewicz E V; Johnston J F; Bennett C F; Monia B P
Inhibition of C-raf expression by antisense oligonucleotides extends heart allograft survival in rats.
Transplantation 2000;70(4):656-61.
2000: Stepkowski S M
Development of antisense oligodeoxynucleotides for transplantation.
Current opinion in molecular therapeutics 2000;2(3):304-17.
2000: Stepkowski S M; Kirken R A
The role of IL-2 in allograft rejection--a lesson learned from experimental work.
Transplantation 2000;69(12):2480-2.
2000: Kahan B D; Stepkowski S M; Napoli K L; Katz S M; Knight R J; Van Buren C
The development of sirolimus: The University of Texas-Houston experience.
Clinical transplants 2000;():145-58.
1999: Akioka K; Kirkin R; Wang M; Tian L; Yu J; Stepkowski S M; Kahan B D
Reduced expression of NF-AT and NF-kappa B transcription factors in tolerant recipients treated with tolerogenic allochimeric donor/recipient class I MHC protein.
Transplantation proceedings 1999;31(7):2745-6.
1999: Chen W; Bennett C F; Wang M E; Dragun D; Tian L; Stecker K; Clark J H; Kahan B D; Stepkowski S M
Perfusion of kidneys with unformulated "naked" intercellular adhesion molecule-1 antisense oligodeoxynucleotides prevents ischemic/reperfusion injury.
Transplantation 1999;68(6):880-7.
1999: Tian L; Wang M; Yu J; Kahan B D; Stepkowski S M
Nucleotide sequences of three distinct complementary DNA clones encoding rat class II major histocompatibility complex RT1.D beta-chain proteins.
Immunogenetics 1999;49(7-8):735-7.
1999: Perez J; Yu J; Stepkowski S M; Kahan B D
Immunization with Escherichia coli-produced soluble MHC class I proteins induces accelerated rejection or prolonged survival of rat cardiac allografts.
Transplantation proceedings 1999;31(3):1560.
1999: Stepkowski S M; Yu J; Wang M; Kahan B D
Induction of tolerance by oral administration of a tolerogenic allochimeric donor/recipient class I MHC protein.
Transplantation proceedings 1999;31(3):1557.
1999: Wang M; Yu J; Stepkowski S M; Kahan B D
Localization of immunogenic and tolerogenic epitopes in the RT1.A1 alloantigen.
Transplantation proceedings 1999;31(3):1517-8.
1999: Troncoso P; Stepkowski S M; Wang M E; Qu X; Chueh S C; Clark J; Kahan B D
Prophylaxis of acute renal allograft rejection using FTY720 in combination with subtherapeutic doses of cyclosporine.
Transplantation 1999;67(1):145-51.
1998: Depre C; Shipley G L; Chen W; Han Q; Doenst T; Moore M L; Stepkowski S; Davies P J; Taegtmeyer H
Unloaded heart in vivo replicates fetal gene expression of cardiac hypertrophy.
Nature medicine 1998;4(11):1269-75.
1998: Stepkowski S M; Wang M E; Condon T P; Cheng-Flournoy S; Stecker K; Graham M; Qu X; Tian L; Chen W; Kahan B D; Bennett C F
Protection against allograft rejection with intercellular adhesion molecule-1 antisense oligodeoxynucleotides.
Transplantation 1998;66(6):699-707.
1998: Stepkowski S M; Wang M; Qu X; Yu J; Okamoto M; Tejpal N; Kahan B D
Synergistic interaction of FTY720 with cyclosporine or sirolimus to prolong heart allograft survival.
Transplantation proceedings 1998;30(5):2214-6.
1998: Stepkowski S M
Application of antisense oligodeoxynucleotides for organ transplantation.
Transplantation proceedings 1998;30(5):2142-5.
1998: Stepkowski S M
Antisense oligodeoxynucleotides for organ transplantation.
Clinical biochemistry 1998;31(5):375-9.
1998: Boyle M J; Baghdassarian V; Stepkowski S M; Dumble L J; Kahan B D
Intrasplenic liver parenchymal cells in conjunction with low-dose rapamycin and cyclosporine induce a unique and specific prolongation of rat cardiac and small bowel allograft survival.
Cell transplantation 1998;7(3):247-56.
1998: Wang M E; Tejpal N; Qu X; Yu J; Okamoto M; Stepkowski S M; Kahan B D
Immunosuppressive effects of FTY720 alone or in combination with cyclosporine and/or sirolimus.
Transplantation 1998;65(7):899-905.
1998: Napoli K L; Wang M E; Stepkowski S M; Kahan B D
Relative tissue distributions of cyclosporine and sirolimus after concomitant peroral administration to the rat: evidence for pharmacokinetic interactions.
Therapeutic drug monitoring 1998;20(2):123-33.
1997: Chueh S C; Tian L; Wang M; Wang M E; Stepkowski S M; Kahan B D
Induction of tolerance toward rat cardiac allografts by treatment with allochimeric class I MHC antigen and FTY720.
Transplantation 1997;64(10):1407-14.
1997: Tian L; Stepkowski S M; Qu X; Wang M E; Wang M; Yu J; Kahan B D
Cytokine mRNA expression in tolerant heart allografts after immunosuppression with cyclosporine, sirolimus or brequinar.
Transplant immunology 1997;5(3):189-98.
1997: Wang M; Stepkowski S M; Yu J; Wang M; Kahan B D
Localization of cryptic tolerogenic epitopes in the alpha1-helical region of the RT1.Au alloantigen.
Transplantation 1997;63(10):1373-9.
1997: Stepkowski S M; Wang M; Langowski J; Ghobrial R; Qu X; Yu J; Tian L; Kahan B D
Localization of tolerogenic epitopes in the alpha 1 helical region of the rat class I major histocompatibility complex molecule.
Transplantation proceedings 1997;29(3):1663-4.
1997: Wang M; Stepkowski S M; Tian L; Langowski J; Yu J; Kloc M; Kahan B D
Nucleotide sequences of rat cDNA clones coding heavy chain class I major histocompatibility complex proteins.
Transplantation proceedings 1997;29(3):1661-2.
1997: Stepkowski S M; Tian L; Napoli K L; Ghobrial R; Wang M E; Chou T C; Kahan B D
Synergistic mechanisms by which sirolimus and cyclosporin inhibit rat heart and kidney allograft rejection.
Clinical and experimental immunology 1997;108(1):63-8.
1997: Napoli K L; Wang M E; Stepkowski S M; Kahan B D
Distribution of sirolimus in rat tissue.
Clinical biochemistry 1997;30(2):135-42.
1997: Katz S M; Tian L; Stepkowski S M; Phan T; Bennett C F; Kahan B D
Effect of ICAM-1/LFA-1 blockade on pancreatic islet allograft survival, function, and early cytokine production.
Transplantation proceedings 1997;29(1-2):748-9.
1997: Stepkowski S M; Wang M E; Amante A; Kalinin D; Qu X; Blasdel T; Condon T; Kahan B D; Bennett F C
Antisense ICAM-1 oligonucleotides block allograft rejection in rats.
Transplantation proceedings 1997;29(1-2):1285.
1997: Wang M; Yu J; Wang M E; Tian L; Stepkowski S M; Kahan B D
Induction of donor-specific tolerance by chimeric class I MHC molecules bearing donor alpha 1 helical amino acids.
Transplantation proceedings 1997;29(1-2):1224-5.
1997: Stepkowski S M; Tian L; Wang M E; Qu X; Napoli K; Kahan B D
Sirolimus in transplantation.
Archivum immunologiae et therapiae experimentalis 1997;45(5-6):383-90.
1996: He G; Wang M; Xu H; Tian L; Yu J; Stepkowski S M; Kahan B D
Impact of different forms of recipient antigen and different routes of antigen administration in donor pretreatment for preventing graft-versus-host disease in rat small bowel transplantation.
Transplantation proceedings 1996;28(5):2469.
1996: Ghobrial R R; Hamashima T; Wang M E; Wang M; Stepkowski S M; Kahan B D
Induction of transplantation tolerance by chimeric donor/recipient class I RT1.Aa molecules.
Transplantation 1996;62(7):1002-10.
1996: Stepkowski S M; Napoli K L; Wang M E; Qu X; Chou T C; Kahan B D
Effects of the pharmacokinetic interaction between orally administered sirolimus and cyclosporine on the synergistic prolongation of heart allograft survival in rats.
Transplantation 1996;62(7):986-94.
1996: Wang M; Qu X; Stepkowski S M; Chou T C; Kahan B D
Beneficial effect of graft perfusion with anti-T cell receptor monoclonal antibodies on survival of small bowel allografts in rat recipients treated with brequinar alone or in combination with cyclosporine and sirolimus.
Transplantation 1996;61(3):458-64.
1996: Wang M; Stepkowski S M; Wang M E; Tian L; Qu X; Tu Y; He G; Kahan B D
Induction of specific allograft immunity by soluble class I MHC heavy chain protein produced in a baculovirus expression system.
Transplantation 1996;61(3):448-57.
1996: Wang M; Stepkowski S M; Hebert J S; Tian L; Yu J; Kahan B D
Nucleotide sequences of three H-2K and three H-2D complementary DNA clones coding mouse class I MHC heavy chain proteins.
Annals of transplantation : quarterly of the Polish Transplantation Society 1996;1(3):26-31.
1996: Stepkowski S M
Sirolimus, a potent new immunosuppressive drug for organ transplantation.
Annals of transplantation : quarterly of the Polish Transplantation Society 1996;1(3):19-25.
1996: Ghobrial R; Karczewski M; Ferraresso M; Tian L; Stepkowski S M; Kahan B D
Kinetics of in vitro immune responses of T and B cells during tolerance induction by sirolimus.
Annals of transplantation : quarterly of the Polish Transplantation Society 1996;1(4):22-9.
1996: Wang M; Stepkowski S M; Tian L; Langowski J L; Yu J; Kahan B D
Nucleotide sequences of three distinct clones coding for rat heavy chain class I major histocompatibility antigens.
Immunogenetics 1996;43(5):318-20.
1996: Wang M; Stepkowski S M; Tian L; Langowski J L; Hebert J S; Kloc M; Yu J; Kahan B D
Nucleotide sequences of three distinct cDNA clones coding for the rat class I heavy chain RT1n antigen.
Immunogenetics 1996;45(1):73-5.
1995: Hamashima T; Stepkowski S M; Chou T C; Kahan B D
Synergistic interaction of 3 M KCl-extracted donor antigens (e-HAg) with cyclosporine or cyclosporine/sirolimus for prolongation of rat heart allograft survival.
Transplant immunology 1995;3(4):335-41.
1995: Katz S M; Browne B; Phan T; Wang M E; Bennett C F; Stepkowski S M; Kahan B D
Efficacy of ICAM-1 antisense oligonucleotide in pancreatic islet transplantation.
Transplantation proceedings 1995;27(6):3214.
1995: Ghobrial R; Hamashima T; Kloc M; Etkin L; Stepkowski S M; Kahan B D
Membrane-bound or soluble truncated RT1.Aa rat class I major histocompatibility antigens induce specific alloimmunity.
Transplantation 1995;60(6):602-10.
1995: Ghobrial R R; Stepkowski S M; Kahan B D
Molecular engineering of the major histocompatibility complex for immunomodulation.
Clinical transplantation 1995;9(3 Pt 2):237-45.
1995: Wang M; Stepkowski S M; Kahan B D
Donor pretreatment with anti-T-cell receptor monoclonal antibodies prevents graft-vs-host disease in brequinar-treated small bowel allograft recipients.
Transplantation proceedings 1995;27(1):383.
1995: Ghobrial R; Hamashima T; Stepkowski S M; Kahan B D
Induction of transplantation tolerance by perioperative injection of "quasi-self" chimeric class I MHC antigen combined with a short cyclosporine course.
Transplantation proceedings 1995;27(1):239-40.
1995: Hamashima T; Stepkowski S M; Kahan B D
Dose-dependent effect of intrathymically injected 3-mol/L KCl-extracted histocompatibility antigens to prolong heart allograft survival in rats.
Transplantation proceedings 1995;27(1):134-5.
1995: Stepkowski S M; Tu Y; Condon T P; Bennett C F
Induction of transplantation tolerance by treatment with ICAM-1 antisense oligonucleotides and anti-LFA-1 monoclonal antibodies.
Transplantation proceedings 1995;27(1):113.
1995: Tu Y; Stepkowski S M; Chou T C; Kahan B D
The synergistic effects of cyclosporine, sirolimus, and brequinar on heart allograft survival in mice.
Transplantation 1995;59(2):177-83.
1994: Stepkowski S M; Tu Y; Condon T P; Bennett C F
Blocking of heart allograft rejection by intercellular adhesion molecule-1 antisense oligonucleotides alone or in combination with other immunosuppressive modalities.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(11):5336-46.
1994: Ferraresso M; Tian L; Ghobrial R; Stepkowski S M; Kahan B D
Rapamycin inhibits production of cytotoxic but not noncytotoxic antibodies and preferentially activates T helper 2 cells that mediate long-term survival of heart allografts in rats.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(7):3307-18.
1994: Hamashima T; Stepkowski S M; Smith S; Kahan B D
Synergistic effect of 3M KCl-extracted donor antigens with cyclosporine or cyclosporine/rapamycin to prolong heart allograft survival in rats.
Transplantation proceedings 1994;26(5):3053-5.
1994: Ferraresso M; Knight R; Tu Y; Stepkowski S M; Kahan B D
Triple combination of cyclosporine, brequinar, and rapamycin prolongs kidney allograft survival in the mongrel dog.
Transplantation proceedings 1994;26(5):3028.
1994: Stepkowski S M; Tu Y; Chou T C; Kahan B D
Synergistic interactions of cyclosporine, rapamycin, and brequinar on heart allograft survival in mice.
Transplantation proceedings 1994;26(5):3025-7.
1994: Kahan B D; Chou T; Tejpal N; Wang M; Chee C; Stepkowski S
Synergistic effects of cyclosporin analogs--A, D, G, IMM-125--with rapamycin and/or brequinar.
Transplantation proceedings 1994;26(5):3021-4.
1994: Stepkowski S M
Transplantation immunobiology. An update.
The Surgical clinics of North America 1994;74(5):991-1013.
1994: Hamashima T; Stepkowski S M; Smith S; Kahan B D
Induction of transplantation tolerance by a single intrathymic injection of 3M KCl-extracted donor histocompatibility antigens combined with two doses of anti-rat alpha/beta-T cell receptor monoclonal antibodies.
Transplantation 1994;58(1):105-7.
1994: Knight R J; Kurrle R; Stepkowski S; Serino F; Chou T C; Kahan B D
Synergistic immunosuppressive actions of cyclosporine with a mouse anti-rat alpha/beta-T cell receptor monoclonal antibody.
Transplantation 1994;57(11):1544-8.
1993: Wang M; Tu Y; Stepkowski S M; Kahan B D
Effect of cyclosporine alone or in combination with rapamycin and brequinar on survival of hamster heart xenograft in rats.
Transplantation proceedings 1993;25(5):2876-7.
1993: Stepkowski S M; Ghobrial R; Wang B; Ito Y; Goto S; Hamashima T; Kahan B D
Donor-soluble histocompatibility antigen selectively potentiates suppressor elements while decreasing the frequency of alloantigen-specific T cytotoxic cells.
Transplantation proceedings 1993;25(5):2875.
1993: Ferraresso M; Rigotti P; Stepkowski S M; Chou T C; Kahan B D
Immunosuppressive effects of defibrotide.
Transplantation 1993;56(4):928-33.
1993: Stepkowski S M; Kahan B D
Synergistic activity of the triple combination: cyclosporine, rapamycin, and brequinar.
Transplantation proceedings 1993;25(3 Suppl 2):29-31.
1993: Kahan B D; Tejpal N; Gibbons-Stubbers S; Tu Y; Wang M; Stepkowski S; Chou T C
The synergistic interactions in vitro and in vivo of brequinar sodium with cyclosporine or rapamycin alone and in triple combination.
Transplantation 1993;55(4):894-900.
1993: Ferraresso M; Ghobrial R; Stepkowski S M; Kahan B D
The mechanism of unresponsiveness to allografts induced by rapamycin and rapamycin/cyclosporine treatment in rats.
Transplantation 1993;55(4):888-94.
1993: Lahiri-Munir D; Zhang B X; Stepkowski S M; Li T; Garcia C A
Transplantation of allogeneic retinal pigment epithelium under the kidney capsule.
Transplantation proceedings 1993;25(1 Pt 2):1017-8.
1993: Ferraresso M; Wang M E; Stepkowski S M; Kahan B D
Rescue therapy with rapamycin blocks an ongoing process of heart allograft rejection.
Transplantation proceedings 1993;25(1 Pt 1):729.
1993: Stepkowski S M; Tian L; Kloc M
Interleukin-2 antisense oligonucleotides inhibit T-cell function.
Transplantation proceedings 1993;25(1 Pt 1):125.
1992: Wang M E; Stepkowski S M; Ferraresso M; Kahan B D
Evidence that rapamycin rescue therapy delays rejection of major (MHC) plus minor (non-MHC) histoincompatible heart allografts in rats.
Transplantation 1992;54(4):704-9.
1992: Goto S; Stepkowski S M; Kahan B D
Benefit of multiple over single doses of 3M KCL-extracted histocompatibility antigen in the potentiating cyclosporine-induced prolongation of rat cardiac allograft survival.
Transplantation 1992;53(3):705-7.
1992: Stepkowski S M; Chen H F; Wang M E; Daloze P; Kahan B D
Inhibition of host-versus-graft and graft-versus-host responses after small bowel transplantation in rats by rapamycin.
Transplantation 1992;53(2):258-64.
1991: Stepkowski S M; Kahan B D
Rapamycin and cyclosporine synergistically prolong heart and kidney allograft survival.
Transplantation proceedings 1991;23(6):3262-4.
1991: Miyagawa S; Stepkowski S M; Lawen J G; Rutzky L P; Kahan B D
In vitro correlates of in vivo therapy with cyclosporine to immunosuppress rejection of heterotopic rat cardiac allografts across strong (RT-1) plus weak (non-RT-1) histocompatibility differences.
Transplantation 1991;52(5):851-7.
1991: Vathsala A; Goto S; Yoshimura N; Stepkowski S; Chou T C; Kahan B D
The immunosuppressive antagonism of low doses of FK506 and cyclosporine.
Transplantation 1991;52(1):121-8.
1991: Stepkowski S M; Goto S; Wiggins J; Christopher J; Kahan B D
Contribution of CD4+ cells to allorejection across a class I major histocompatibility complex barrier in congeneic rats.
Transplantation proceedings 1991;23(1 Pt 1):172-3.
1991: Kahan B D; Gibbons S; Tejpal N; Chou T C; Stepkowski S
Synergistic effect of the rapamycin-cyclosporine combination: median effect analysis of in vitro immune performances by human T lymphocytes in PHA, CD3, and MLR proliferative and cytotoxicity assays.
Transplantation proceedings 1991;23(1 Pt 2):1090-1.
1991: Goto S; Stepkowski S M; Kahan B D
Effect of FK 506 and cyclosporine on heart allograft survival in rats.
Transplantation proceedings 1991;23(1 Pt 1):529-30.
1991: Miyagawa S; Stepkowski S M; Kahan B D
Mechanism of unresponsiveness in rats induced by a short course of FK 506 or CyA.
Transplantation proceedings 1991;23(1 Pt 1):334-5.
1991: Kahan B D; Gibbons S; Tejpal N; Stepkowski S M; Chou T C
Synergistic interactions of cyclosporine and rapamycin to inhibit immune performances of normal human peripheral blood lymphocytes in vitro.
Transplantation 1991;51(1):232-9.
1991: Stepkowski S M; Chen H; Daloze P; Kahan B D
Rapamycin, a potent immunosuppressive drug for vascularized heart, kidney, and small bowel transplantation in the rat.
Transplantation 1991;51(1):22-6.
1990: Stepkowski S M; Ito T
Frequency of alloantigen-specific T cytotoxic cells in high- and low-responder recipients of class I MHC-disparate heart allografts.
Transplantation 1990;50(1):112-9.
1990: Florence L S; Jiang G L; Ang K K; Stepkowski S M; Kahan B D
In vitro analysis of T cell-mediated cytotoxicity displayed by rat heart allograft recipients rendered unresponsive by total-lymphoid irradiation and extracted donor antigen.
Transplantation 1990;49(2):436-44.
1990: Ito T; Stepkowski S M; Kahan B D
Soluble antigen and cyclosporine-induced specific unresponsiveness in rats. Frequency of alloantigen-specific T cytotoxic cells in normal, sensitized, and unresponsive rats.
Transplantation 1990;49(2):422-8.
1989: Stepkowski S M; Ito T
Rejection mechanism of class I disparate heart allografts in a rat model.
Transplantation proceedings 1989;21(2):3303-6.
1989: Goto S; Stepkowski S M; Kahan B D
Multiple injections of KCl-extracted donor-antigen in combination with a short course of cyclosporine therapy induces prolonged heart allograft survival in rats.
Transplantation proceedings 1989;21(2):3300-2.
1989: Ito T; Stepkowski S M
Frequency of T cytotoxic cells correlates with the immune status of organ allograft recipients.
Transplantation proceedings 1989;21(2):3282-5.
1989: Ito T; Stepkowski S M; Kahan B D
Decreased frequency of alloantigen-specific T cells following immunosuppression with extracted donor histocompatibility antigen and a brief course of cyclosporine.
Transplantation proceedings 1989;21(1 Pt 1):248-51.
1989: Stepkowski S; Goto S; Reynolds K; Ito T; Kahan B D
Induction of unresponsiveness after local low-dose cyclosporine administration.
Transplantation proceedings 1989;21(1 Pt 1):1120-2.
1989: Stepkowski S M; Goto S; Ito T; Reynolds K; Didlake R; Kim E K; Kahan B D
Prolongation of heterotopic heart allograft survival by local delivery of continuous low-dose cyclosporine therapy.
Transplantation 1989;47(1):17-23.
1989: Florence L S; Ito T; Ang K K; Jiang G L; Wong C S; Goto S; Didlake R; Kim E K; Stepkowski S; Kahan B D
The synergistic effect of total-lymphoid irradiation with extracted donor alloantigen in inducing transplantation unresponsiveness.
Transplantation 1989;47(1):156-62.
1988: Ito T; Stepkowski S; Kahan B D
Frequency of T cytotoxic cells after perioperative treatment with extracted antigen and cyclosporine in rat cardiac transplantation.
Transplantation proceedings 1988;20(3 Suppl 3):1045-52.
1988: Kahan B D; Didlake R; Kim E E; Yoshimura N; Kondo E; Stepkowski S
Important role of cyclosporine for the induction of immunologic tolerance in adult hosts.
Transplantation proceedings 1988;20(3 Suppl 3):23-35.
1988: Kahan B D; Didlake R; Kim E E; Yoshimura N; Kondo E; Stepkowski S
Important role of cyclosporine for the induction of immunologic tolerance in adult hosts.
Transplantation proceedings 1988;20(2 Suppl 2):438-50.

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