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Karen Stevens

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Randal G Ross; Karen E Stevens; Brandie D Wagner; Julie Beuler; Sharon K Hunter; Amanda K Hutchison; Sherry Leonard; Lizbeth McCarthy; Robert Freedman
Perinatal choline effects on neonatal pathophysiology related to later schizophrenia risk.
Ryan C Bates; Bradley J Stith; Karen E Stevens
Chronic central administration of valproic acid: Increased pro-survival phospho-proteins and growth cone associated proteins with no behavioral pathology.
Catherine E Adams; Sharon L Graw; Kalynn M Schulz; J Stitzel; P U Teschke; J C Yonchek; Karen E Stevens
Reduced Chrna7 expression in mice is associated with decreases in hippocampal markers of inhibitory function: implications for neuropsychiatric diseases.

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All Publications

2013: Randal G Ross; Karen E Stevens; Brandie D Wagner; Julie Beuler; Sharon K Hunter; Amanda K Hutchison; Sherry Leonard; Lizbeth McCarthy; Robert Freedman
Perinatal choline effects on neonatal pathophysiology related to later schizophrenia risk.
The American journal of psychiatry 2013;170(3):290-8.
2012: Ryan C Bates; Bradley J Stith; Karen E Stevens
Chronic central administration of valproic acid: Increased pro-survival phospho-proteins and growth cone associated proteins with no behavioral pathology.
Pharmacology, biochemistry, and behavior 2012;103(2):237-44.
2012: Catherine E Adams; Sharon L Graw; Kalynn M Schulz; J Stitzel; P U Teschke; J C Yonchek; Karen E Stevens
Reduced Chrna7 expression in mice is associated with decreases in hippocampal markers of inhibitory function: implications for neuropsychiatric diseases.
Neuroscience 2012;207():274-82.
2011: Kalynn M Schulz; Catherine E Adams; Ralph Berger; Sherry Leonard; Eric W Neeley; Jennifer N Pearson; Karen E Stevens
Maternal stress during pregnancy causes sex-specific alterations in offspring memory performance, social interactions, indices of anxiety, and body mass.
Physiology & behavior 2011;104(2):340-7.
2010: Karen E Stevens; Brandon Cornejo; Catherine E Adams; Lijun Zheng; Joan Yonchek; Keith L Hoffman; Uwe Christians; William R Kem
Continuous administration of a selective alpha7 nicotinic partial agonist, DMXBA, improves sensory inhibition without causing tachyphylaxis or receptor upregulation in DBA/2 mice.
Brain research 2010;1352():140-6.
2010: Randal G Ross; Karen E Stevens; William R Proctor; Sherry Leonard; Michael A Kisley; Sharon K Hunter; Robert Freedman; Catherine E Adams
Research review: Cholinergic mechanisms, early brain development, and risk for schizophrenia.
Journal of child psychology and psychiatry, and allied disciplines 2010;51(5):535-49.
2009: Kristin M Wildeboer; Lijun Zheng; Kevin S Choo; Karen E Stevens
Ondansetron results in improved auditory gating in DBA/2 mice through a cholinergic mechanism.
Brain research 2009;1300():41-50.
2008: Karen E Stevens; Catherine E Adams; Tiffany Mellott; Emily Robbins; Michael A Kisley
Perinatal choline deficiency produces abnormal sensory inhibition in Sprague-Dawley rats.
Brain research 2008;1237():84-90.
2008: Johanna K Simosky; Robert Freedman; Karen E Stevens
Olanzapine improves deficient sensory inhibition in DBA/2 mice.
Brain research 2008;1233():129-36.
2008: Kristin M Wildeboer; Karen E Stevens
Stimulation of the alpha4beta2 nicotinic receptor by 5-I A-85380 improves auditory gating in DBA/2 mice.
Brain research 2008;1224():29-36.
2008: Robert Freedman; Ann Olincy; Robert W Buchanan; Josette G Harris; James M Gold; Lynn Johnson; Diana Allensworth; Alejandrina Guzman-Bonilla; Bettye Clement; M Patricia Ball; Jay Kutnick; Vicki Pender; Laura F Martin; Karen E Stevens; Brandie D Wagner; Gary O Zerbe; Ferenc Soti; William R Kem
Initial phase 2 trial of a nicotinic agonist in schizophrenia.
The American journal of psychiatry 2008;165(8):1040-7.
2008: Karen E Stevens; Catherine E Adams; Joan Yonchek; Cindy Hickel; Jeffrey Danielson; Michael A Kisley
Permanent improvement in deficient sensory inhibition in DBA/2 mice with increased perinatal choline.
Psychopharmacology 2008;198(3):413-20.
2008: Daniel J Abrams; Lijun Zheng; Kevin S Choo; Jun J Yang; Wei Wei; Thomas J Anchordoquy; Nasser H Zawia; Karen E Stevens
An initial animal proof-of-concept study for central administration of clozapine to schizophrenia patients.
Schizophrenia research 2008;100(1-3):86-96.
2008: Catherine E Adams; J C Yonchek; L Zheng; Allan C Collins; Karen E Stevens
Altered hippocampal circuit function in C3H alpha7 null mutant heterozygous mice.
Brain research 2008;1194():138-45.
2007: Ann Olincy; Karen E Stevens
Treating schizophrenia symptoms with an alpha7 nicotinic agonist, from mice to men.
Biochemical pharmacology 2007;74(8):1192-201.
2006: Karen E Stevens; Heidi C O'Neill; Gregory M Rose; Johan Luthman
The 5-HT(1A) receptor active compounds (R)-8-OH-DPAT and (S)-UH-301 modulate auditory evoked EEG responses in rats.
Amino acids 2006;31(4):365-75.
2006: Ann Olincy; Josette G Harris; Lynn L Johnson; Vicki Pender; Susan Kongs; Diana Allensworth; Jamey Ellis; Gary O Zerbe; Sherry Leonard; Karen E Stevens; James O Stevens; Laura Martin; Lawrence E Adler; Ferenc Soti; William R Kem; Robert Freedman
Proof-of-concept trial of an alpha7 nicotinic agonist in schizophrenia.
Archives of general psychiatry 2006;63(6):630-8.
2005: Robert Freedman; Randal Ross; Sherry Leonard; Marina Myles-Worsley; Catherine E Adams; Merilyne C Waldo; Jason R Tregellas; Laura Martin; Ann Olincy; Jody Tanabe; Michael A Kisley; Sharon Hunter; Karen E Stevens
Early biomarkers of psychosis.
Dialogues in clinical neuroscience 2005;7(1):17-29.
2003: Heidi C O'Neill; Mischel P Schmitt; Karen E Stevens
Lithium alters measures of auditory gating in two strains of mice.
Biological psychiatry 2003;54(8):847-53.
2003: Heidi C O'Neill; Kate Rieger; William R Kem; Karen E Stevens
DMXB, an alpha7 nicotinic agonist, normalizes auditory gating in isolation-reared rats.
Psychopharmacology 2003;169(3-4):332-9.
2003: Robert Freedman; Ann Olincy; Randal G Ross; Merilyne C Waldo; Karen E Stevens; Lawrence E Adler; Sherry Leonard
The genetics of sensory gating deficits in schizophrenia.
Current psychiatry reports 2003;5(2):155-61.
2003: Johanna K Simosky; Karen E Stevens; Lawrence E Adler; Robert Freedman
Clozapine improves deficient inhibitory auditory processing in DBA/2 mice, via a nicotinic cholinergic mechanism.
Psychopharmacology 2003;165(4):386-96.
2002: Johanna K Simosky; Karen E Stevens; Robert Freedman
Nicotinic agonists and psychosis.
Current drug targets. CNS and neurological disorders 2002;1(2):149-62.
2002: Robert Freedman; Lawrence E Adler; Ann Olincy; Merilyne C Waldo; Randal G Ross; Karen E Stevens; Sherry Leonard
Input dysfunction, schizotypy, and genetic models of schizophrenia.
Schizophrenia research 2002;54(1-2):25-32.
2001: Johanna K Simosky; Karen E Stevens; William R Kem; Robert Freedman
Intragastric DMXB-A, an alpha7 nicotinic agonist, improves deficient sensory inhibition in DBA/2 mice.
Biological psychiatry 2001;50(7):493-500.
2001: Karen E Stevens; A E Bullock; Allan C Collins
Chronic corticosterone treatment alters sensory gating in C3H mice.
Pharmacology, biochemistry, and behavior 2001;69(3-4):359-66.
2000: Catherine E Adams; Karen E Stevens; William R Kem; Robert Freedman
Inhibition of nitric oxide synthase prevents alpha 7 nicotinic receptor-mediated restoration of inhibitory auditory gating in rat hippocampus.
Brain research 2000;877(2):235-44.
2000: Robert Freedman; Catherine E Adams; Lawrence E Adler; Paula C Bickford; Judith Gault; Josette G Harris; Herbert T Nagamoto; Ann Olincy; Randal G Ross; Karen E Stevens; Merilyne C Waldo; Sherry Leonard
Inhibitory neurophysiological deficit as a phenotype for genetic investigation of schizophrenia.
American journal of medical genetics 2000;97(1):58-64.
1999: Karen E Stevens; William R Kem; Robert Freedman
Selective alpha 7 nicotinic receptor stimulation normalizes chronic cocaine-induced loss of hippocampal sensory inhibition in C3H mice.
Biological psychiatry 1999;46(10):1443-50.
1998: Catherine E Adams; Karen E Stevens
Inhibition of nitric oxide synthase disrupts inhibitory gating of auditory responses in rat hippocampus.
The Journal of pharmacology and experimental therapeutics 1998;287(2):760-5.
1998: RG Johnson; Karen E Stevens; Gregory M Rose
5-Hydroxytryptamine2 receptors modulate auditory filtering in the rat.
The Journal of pharmacology and experimental therapeutics 1998;285(2):643-50.
1998: Karen E Stevens; William R Kem; Vladimir M Mahnir; Robert Freedman
Selective alpha7-nicotinic agonists normalize inhibition of auditory response in DBA mice.
Psychopharmacology 1998;136(4):320-7.
1998: Karen E Stevens; Herbert T Nagamoto; RG Johnson; Catherine E Adams; Gregory M Rose
Kainic acid lesions in adult rats as a model of schizophrenia: changes in auditory information processing.
Neuroscience 1998;82(3):701-8.
1997: Karen E Stevens; RG Johnson; Gregory M Rose
Rats reared in social isolation show schizophrenia-like changes in auditory gating.
Pharmacology, biochemistry, and behavior 1997;58(4):1031-6.
1997: Karen E Stevens; K D Wear
Normalizing effects of nicotine and a novel nicotinic agonist on hippocampal auditory gating in two animal models.
Pharmacology, biochemistry, and behavior 1997;57(4):869-74.
1996: Karen E Stevens; Robert Freedman; A C Collins; M Hall; Sherry Leonard; M J Marks; Gregory M Rose
Genetic correlation of inhibitory gating of hippocampal auditory evoked response and alpha-bungarotoxin-binding nicotinic cholinergic receptors in inbred mouse strains.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1996;15(2):152-62.
1996: Karen E Stevens; Johan Luthman; E Lindqvist; R G Johnson; Gregory M Rose
Effects of neonatal dopamine depletion on sensory inhibition in the rat.
Pharmacology, biochemistry, and behavior 1996;53(4):817-23.
1996: Sherry Leonard; C Adams; CR Breese; Lawrence E Adler; Paula C Bickford; William Byerley; Hilary Coon; J M Griffith; Christine L Miller; Marina Myles-Worsley; Herbert T Nagamoto; Yvonne D Rollins; Karen E Stevens; Merilyne C Waldo; Robert Freedman
Nicotinic receptor function in schizophrenia.
Schizophrenia bulletin 1996;22(3):431-45.
1995: Karen E Stevens; J Meltzer; Gregory M Rose
Nicotinic cholinergic normalization of amphetamine-induced loss of auditory gating in freely moving rats.
Psychopharmacology 1995;119(2):163-70.
1993: Karen E Stevens; J Meltzer; Gregory M Rose
Disruption of sensory gating by the alpha 2 selective noradrenergic antagonist yohimbine.
Biological psychiatry 1993;33(2):130-2.
1991: Karen E Stevens; L L Fuller; Gregory M Rose
Dopaminergic and noradrenergic modulation of amphetamine-induced changes in auditory gating.
Brain research 1991;555(1):91-8.
1990: D A Engstrom; M C Bennett; Karen E Stevens; R L Wilson; David M Diamond; Monika Fleshner; Gregory M Rose
Modulation of hippocampal primed burst potentiation by anesthesia.
Brain research 1990;521(1-2):148-52.