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Martin Stevens

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TOP 3
Michael Kuehl; Martin J Stevens
Cardiovascular autonomic neuropathies as complications of diabetes mellitus.
Milan K Piya; Rodica Pop-Busui; Ganesh Nallur Shivu; Khalid Abozguia; Kiran Dubb; Michael Frenneaux; Parth Narendran; T T Phan; Abd A Tahrani; Martin J Stevens
Abnormal left ventricular torsion and cardiac autonomic dysfunction in subjects with type 1 diabetes mellitus.
Abd A Tahrani; Trevor Askwith; Martin J Stevens
Emerging drugs for diabetic neuropathy.

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All Publications

2012: Michael Kuehl; Martin J Stevens
Cardiovascular autonomic neuropathies as complications of diabetes mellitus.
Nature reviews. Endocrinology 2012;8(7):405-16.
2011: Milan K Piya; Rodica Pop-Busui; Ganesh Nallur Shivu; Khalid Abozguia; Kiran Dubb; Michael Frenneaux; Parth Narendran; T T Phan; Abd A Tahrani; Martin J Stevens
Abnormal left ventricular torsion and cardiac autonomic dysfunction in subjects with type 1 diabetes mellitus.
Metabolism: clinical and experimental 2011;60(8):1115-21.
2010: Abd A Tahrani; Trevor Askwith; Martin J Stevens
Emerging drugs for diabetic neuropathy.
Expert opinion on emerging drugs 2010;15(4):661-83.
2010: Roman Stavniichuk; Viktor Drel; Hanna Shevalye; Igor Vareniuk; Martin J Stevens; Jerry L Nadler; Irina G Obrosova
Role of 12/15-lipoxygenase in nitrosative stress and peripheral prediabetic and diabetic neuropathies.
Free radical biology & medicine 2010;49(6):1036-45.
2009: Rodica Pop-Busui; Elif Arioglu Oral; David M Raffel; Jaeman Byun; Valida Bajirovic; Anuradha Vivekanandan-Giri; Aaron Kellogg; Subramaniam Pennathur; Martin J Stevens
Impact of rosiglitazone and glyburide on nitrosative stress and myocardial blood flow regulation in type 2 diabetes mellitus.
Metabolism: clinical and experimental 2009;58(7):989-94.
2007: Aaron P Kellogg; Tim D Wiggin; Dennis Larkin; John M Hayes; Martin J Stevens; Rodica Pop-Busui
Protective effects of cyclooxygenase-2 gene inactivation against peripheral nerve dysfunction and intraepidermal nerve fiber loss in experimental diabetes.
Diabetes 2007;56(12):2997-3005.
2007: Elena A Gillespie; Brenda W Gillespie; Martin J Stevens
Painful diabetic neuropathy: impact of an alternative approach.
Diabetes care 2007;30(4):999-1001.
2007: Martin J Stevens; Fei Li; Viktor Drel; Omorodola I Abatan; H Kim; D Burnett; D Larkin; Irina G Obrosova
Nicotinamide reverses neurological and neurovascular deficits in streptozotocin diabetic rats.
The Journal of pharmacology and experimental therapeutics 2007;320(1):458-64.
2006: Irina G Obrosova; Viktor Drel; Arno K Kumagai; C Szábo; Pal Pacher; Martin J Stevens
Early diabetes-induced biochemical changes in the retina: comparison of rat and mouse models.
Diabetologia 2006;49(10):2525-33.
2006: Olga Ilnytska; Valeriy V Lyzogubov; Martin J Stevens; Viktor Drel; Nazar Mashtalir; Pal Pacher; Mark A Yorek; Irina G Obrosova
Poly(ADP-ribose) polymerase inhibition alleviates experimental diabetic sensory neuropathy.
Diabetes 2006;55(6):1686-94.
2006: Fei Li; Omorodola I Abatan; Howard Kim; Diana Burnett; Dennis Larkin; Irina G Obrosova; Martin J Stevens
Taurine reverses neurological and neurovascular deficits in Zucker diabetic fatty rats.
Neurobiology of disease 2006;22(3):669-76.
2006: Viktor Drel; Pal Pacher; Martin J Stevens; Irina G Obrosova
Aldose reductase inhibition counteracts nitrosative stress and poly(ADP-ribose) polymerase activation in diabetic rat kidney and high-glucose-exposed human mesangial cells.
Free radical biology & medicine 2006;40(8):1454-65.
2006: Catherine L Martin; James Albers; William H Herman; Patricia Cleary; Barbara Waberski; Douglas A Greene; Martin J Stevens; Eva L Feldman
Neuropathy among the diabetes control and complications trial cohort 8 years after trial completion.
Diabetes care 2006;29(2):340-4.
2005: Irina G Obrosova; Viktor Drel; Pal Pacher; Olga Ilnytska; Zhong Q Wang; Martin J Stevens; Mark A Yorek
Oxidative-nitrosative stress and poly(ADP-ribose) polymerase (PARP) activation in experimental diabetic neuropathy: the relation is revisited.
Diabetes 2005;54(12):3435-41.
2005: Eitaro Nakashima; Rodica Pop-Busui; Roberto Towns; Thommey P Thomas; Yoshiuki Hosaka; Jiro Nakamura; Douglas A Greene; Paul D Killen; Justin Schroeder; Dennis Larkin; Yuk Lam Ho; Martin J Stevens
Regulation of the human taurine transporter by oxidative stress in retinal pigment epithelial cells stably transformed to overexpress aldose reductase.
Antioxidants & redox signaling 2005;7(11-12):1530-42.
2005: Andrea M Vincent; Martin J Stevens; Carey Backus; Lisa L McLean; Eva L Feldman
Cell culture modeling to test therapies against hyperglycemia-mediated oxidative stress and injury.
Antioxidants & redox signaling 2005;7(11-12):1494-506.
2005: Humaira Lateef; Muhammad Nadeem Aslam; Martin J Stevens; James Varani
Pretreatment of diabetic rats with lipoic acid improves healing of subsequently-induced abrasion wounds.
Archives of dermatological research 2005;297(2):75-83.
2005: Martin J Stevens
Oxidative-nitrosative stress as a contributing factor to cardiovascular disease in subjects with diabetes.
Current vascular pharmacology 2005;3(3):253-66.
2005: Fei Li; Viktor Drel; Csaba Szabó; Martin J Stevens; Irina G Obrosova
Low-dose poly(ADP-ribose) polymerase inhibitor-containing combination therapies reverse early peripheral diabetic neuropathy.
Diabetes 2005;54(5):1514-22.
2005: Humaira Lateef; Omorodola I Abatan; Muhammad Nadeem Aslam; Martin J Stevens; James Varani
Topical pretreatment of diabetic rats with all-trans retinoic acid improves healing of subsequently induced abrasion wounds.
Diabetes 2005;54(3):855-61.
2005: Irina G Obrosova; Pal Pacher; Csaba Szabó; Zsuzsanna Zsengeller; Hiroko Hirooka; Martin J Stevens; Mark A Yorek
Aldose reductase inhibition counteracts oxidative-nitrosative stress and poly(ADP-ribose) polymerase activation in tissue sites for diabetes complications.
Diabetes 2005;54(1):234-42.
2005: Fei Li; Irina G Obrosova; Omorodola I Abatan; Dequan Tian; Dennis Larkin; Edward L Stuenkel; Martin J Stevens
Taurine replacement attenuates hyperalgesia and abnormal calcium signaling in sensory neurons of STZ-D rats.
American journal of physiology. Endocrinology and metabolism 2005;288(1):E29-36.
2005: Martin J Stevens; Dennis Larkin; Eva L Feldman; Monte A Delmonte; Douglas A Greene
Establishment, maintenance, and transfection of in vitro cultures of human retinal pigment epithelium.
Methods in molecular medicine 2005;107():343-51.
2004: Rodica Pop-Busui; Ian Kirkwood; Helena Schmid; Vlad Marinescu; Justin Schroeder; Dennis Larkin; Elina Yamada; David M Raffel; Martin J Stevens
Sympathetic dysfunction in type 1 diabetes: association with impaired myocardial blood flow reserve and diastolic dysfunction.
Journal of the American College of Cardiology 2004;44(12):2368-74.
2004: Martin J Stevens; Weixian Zhang; Fei Li; Anders A F Sima
C-peptide corrects endoneurial blood flow but not oxidative stress in type 1 BB/Wor rats.
American journal of physiology. Endocrinology and metabolism 2004;287(3):E497-505.
2004: Humaira Lateef; Martin J Stevens; James Varani
All-trans-retinoic acid suppresses matrix metalloproteinase activity and increases collagen synthesis in diabetic human skin in organ culture.
The American journal of pathology 2004;165(1):167-74.
2004: Irina G Obrosova; Alexander G Minchenko; Robert N Frank; Gail Seigel; Zsuzsanna Zsengeller; Pal Pacher; Martin J Stevens; Csaba Szabó
Poly(ADP-ribose) polymerase inhibitors counteract diabetes- and hypoxia-induced retinal vascular endothelial growth factor overexpression.
International journal of molecular medicine 2004;14(1):55-64.
2004: Fei Li; Csaba Szabó; Pal Pacher; G J Southan; Omorodola I Abatan; T Charniauskaya; Martin J Stevens; Irina G Obrosova
Evaluation of orally active poly(ADP-ribose) polymerase inhibitor in streptozotocin-diabetic rat model of early peripheral neuropathy.
Diabetologia 2004;47(4):710-7.
2004: Irina G Obrosova; Fei Li; Omorodola I Abatan; Mark A Forsell; Katalin Komjáti; Pal Pacher; Csaba Szabó; Martin J Stevens
Role of poly(ADP-ribose) polymerase activation in diabetic neuropathy.
Diabetes 2004;53(3):711-20.
2003: Alexander G Minchenko; Martin J Stevens; Lauren White; Omorodola I Abatan; Katalin Komjáti; Pal Pacher; Csaba Szabó; Irina G Obrosova
Diabetes-induced overexpression of endothelin-1 and endothelin receptors in the rat renal cortex is mediated via poly(ADP-ribose) polymerase activation.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(11):1514-6.
2003: Irina G Obrosova; Alexander G Minchenko; Rukmini Vasupuram; Lauren White; Omorodola I Abatan; Arno K Kumagai; Robert N Frank; Martin J Stevens
Aldose reductase inhibitor fidarestat prevents retinal oxidative stress and vascular endothelial growth factor overexpression in streptozotocin-diabetic rats.
Diabetes 2003;52(3):864-71.
2002: James Varani; Patricia Perone; Matthew G Merfert; Sang Eun Moon; Dennis Larkin; Martin J Stevens
All-trans retinoic acid improves structure and function of diabetic rat skin in organ culture.
Diabetes 2002;51(12):3510-6.
2002: Jennifer A Kearney; David A Buchner; Georgius De Haan; Maja Adamska; Stephen I Levin; Amy R Furay; Roger L Albin; Julie M Jones; Mauricio Montal; Martin J Stevens; Leslie K Sprunger; Miriam H Meisler
Molecular and pathological effects of a modifier gene on deficiency of the sodium channel Scn8a (Na(v)1.6).
Human molecular genetics 2002;11(22):2765-75.
2002: Rodica Pop-Busui; Vlad Marinescu; Carol Van Huysen; Fei Li; Kelli A Sullivan; Douglas A Greene; Dennis Larkin; Martin J Stevens
Dissection of metabolic, vascular, and nerve conduction interrelationships in experimental diabetic neuropathy by cyclooxygenase inhibition and acetyl-L-carnitine administration.
Diabetes 2002;51(8):2619-28.
2002: Irina G Obrosova; Carol Van Huysen; Lamia Fathallah; Xianghui Cao Cao; Douglas A Greene; Martin J Stevens
An aldose reductase inhibitor reverses early diabetes-induced changes in peripheral nerve function, metabolism, and antioxidative defense.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(1):123-5.
2001: Irina G Obrosova; Lamia Fathallah; Martin J Stevens
Taurine counteracts oxidative stress and nerve growth factor deficit in early experimental diabetic neuropathy.
Experimental neurology 2001;172(1):211-9.
2001: Irina G Obrosova; Alexander G Minchenko; Vlad Marinescu; Lamia Fathallah; A Kennedy; C M Stockert; Robert N Frank; Martin J Stevens
Antioxidants attenuate early up regulation of retinal vascular endothelial growth factor in streptozotocin-diabetic rats.
Diabetologia 2001;44(9):1102-10.
2001: Rodica Pop-Busui; Kelli A Sullivan; Carol Van Huysen; L Bayer; X Cao; Roberto Towns; Martin J Stevens
Depletion of taurine in experimental diabetic neuropathy: implications for nerve metabolic, vascular, and functional deficits.
Experimental neurology 2001;168(2):259-72.
2001: Martin J Stevens
New imaging techniques for cardiovascular autonomic neuropathy: a window on the heart.
Diabetes technology & therapeutics 2001;3(1):9-22.
2001: Irina G Obrosova; Martin J Stevens; HJ Lang
Diabetes-induced changes in retinal NAD-redox status: pharmacological modulation and implications for pathogenesis of diabetic retinopathy.
Pharmacology 2001;62(3):172-80.
2000: Irina G Obrosova; Carol Van Huysen; Lamia Fathallah; X Cao; Martin J Stevens; Douglas A Greene
Evaluation of alpha(1)-adrenoceptor antagonist on diabetes-induced changes in peripheral nerve function, metabolism, and antioxidative defense.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(11):1548-58.
2000: Martin J Stevens; Irina G Obrosova; X Cao; Carol Van Huysen; Douglas A Greene
Effects of DL-alpha-lipoic acid on peripheral nerve conduction, blood flow, energy metabolism, and oxidative stress in experimental diabetic neuropathy.
Diabetes 2000;49(6):1006-15.
2000: Rodica Pop-Busui; William Chey; Martin J Stevens
Severe hypertension induced by the long-acting somatostatin analogue sandostatin LAR in a patient with diabetic autonomic neuropathy.
The Journal of clinical endocrinology and metabolism 2000;85(3):943-6.
1999: Martin J Stevens; Yoshiuki Hosaka; J A Masterson; S M Jones; Thommey P Thomas; Dennis Larkin
Downregulation of the human taurine transporter by glucose in cultured retinal pigment epithelial cells.
The American journal of physiology 1999;277(4 Pt 1):E760-71.
1999: Douglas A Greene; Martin J Stevens; Eva L Feldman
Diabetic neuropathy: scope of the syndrome.
The American journal of medicine 1999;107(2B):2S-8S.
1999: K Kato; Thommey P Thomas; Martin J Stevens; Douglas A Greene; J Nakamura
2-Chloroadenosine reverses hyperglycemia-induced inhibition of phosphoinositide synthesis in cultured human retinal pigment epithelial cells and prevents reduced nerve conduction velocity in diabetic rats.
Metabolism: clinical and experimental 1999;48(7):827-33.
1999: Douglas A Greene; Martin J Stevens; Irina G Obrosova; Eva L Feldman
Glucose-induced oxidative stress and programmed cell death in diabetic neuropathy.
European journal of pharmacology 1999;375(1-3):217-23.
1999: Francesca Porcellati; Yoshiuki Hosaka; T Hlaing; M Togawa; Dennis Larkin; A Karihaloo; Martin J Stevens; Paul D Killen; Douglas A Greene
Alternate splicing in human Na+-MI cotransporter gene yields differentially regulated transport isoforms.
The American journal of physiology 1999;276(6 Pt 1):C1325-37.
1999: H Schmid; L A Forman; X Cao; Phillip S Sherman; Martin J Stevens
Heterogeneous cardiac sympathetic denervation and decreased myocardial nerve growth factor in streptozotocin-induced diabetic rats: implications for cardiac sympathetic dysinnervation complicating diabetes.
Diabetes 1999;48(3):603-8.
1999: Irina G Obrosova; Martin J Stevens
Effect of dietary taurine supplementation on GSH and NAD(P)-redox status, lipid peroxidation, and energy metabolism in diabetic precataractous lens.
Investigative ophthalmology & visual science 1999;40(3):680-8.
1999: Martin J Stevens; David M Raffel; KC Allman; M Schwaiger; Darryl Wieland
Regression and progression of cardiac sympathetic dysinnervation complicating diabetes: an assessment by C-11 hydroxyephedrine and positron emission tomography.
Metabolism: clinical and experimental 1999;48(1):92-101.
1998: Irina G Obrosova; X Cao; Douglas A Greene; Martin J Stevens
Diabetes-induced changes in lens antioxidant status, glucose utilization and energy metabolism: effect of DL-alpha-lipoic acid.
Diabetologia 1998;41(12):1442-50.
1998: Martin J Stevens; David M Raffel; KC Allman; F Dayanikli; Edward P Ficaro; T Sandford; Darryl Wieland; M A Pfeifer; M Schwaiger
Cardiac sympathetic dysinnervation in diabetes: implications for enhanced cardiovascular risk.
Circulation 1998;98(10):961-8.
1998: Martin J Stevens; F Dayanikli; David M Raffel; KC Allman; T Sandford; Eva L Feldman; Darryl Wieland; James R Corbett; M Schwaiger
Scintigraphic assessment of regionalized defects in myocardial sympathetic innervation and blood flow regulation in diabetic patients with autonomic neuropathy.
Journal of the American College of Cardiology 1998;31(7):1575-84.
1998: Francesca Porcellati; T Hlaing; M Togawa; Martin J Stevens; Dennis Larkin; Yoshiuki Hosaka; Thomas W Glover; D N Henry; Douglas A Greene; Paul D Killen
Human Na(+)-myo-inositol cotransporter gene: alternate splicing generates diverse transcripts.
The American journal of physiology 1998;274(5 Pt 1):C1215-25.
1997: Eva L Feldman; Martin J Stevens; Douglas A Greene
Pathogenesis of diabetic neuropathy.
Clinical neuroscience (New York, N.Y.) 1997;4(6):365-70.
1996: Martin J Stevens; S A Lattimer; Eva L Feldman; E D Helton; D S Millington; Anders A F Sima; Douglas A Greene
Acetyl-L-carnitine deficiency as a cause of altered nerve myo-inositol content, Na,K-ATPase activity, and motor conduction velocity in the streptozotocin-diabetic rat.
Metabolism: clinical and experimental 1996;45(7):865-72.
1996: Anders A F Sima; H Ristic; A Merry; M Kamijo; S A Lattimer; Martin J Stevens; Douglas A Greene
Primary preventive and secondary interventionary effects of acetyl-L-carnitine on diabetic neuropathy in the bio-breeding Worcester rat.
The Journal of clinical investigation 1996;97(8):1900-7.
1996: H Shindo; Thommey P Thomas; Dennis Larkin; A K Karihaloo; H Inada; Toshimasa Onaya; Martin J Stevens; Douglas A Greene
Modulation of basal nitric oxide-dependent cyclic-GMP production by ambient glucose, myo-inositol, and protein kinase C in SH-SY5Y human neuroblastoma cells.
The Journal of clinical investigation 1996;97(3):736-45.
1996: Eva L Feldman; Monte A Delmonte; Martin J Stevens; Douglas A Greene
Establishment and maintenance of in vitro cultures of human retinal pigment epithelium.
Methods in molecular medicine 1996;2():517-24.
1995: Martin J Stevens; Eva L Feldman; Douglas A Greene
The aetiology of diabetic neuropathy: the combined roles of metabolic and vascular defects.
Diabetic medicine : a journal of the British Diabetic Association 1995;12(7):566-79.
1995: Martin J Stevens
Nitric oxide as a potential bridge between the metabolic and vascular hypotheses of diabetic neuropathy.
Diabetic medicine : a journal of the British Diabetic Association 1995;12(4):292-5.
1994: Eva L Feldman; Martin J Stevens; P K Thomas; M B Brown; N Canal; Douglas A Greene
A practical two-step quantitative clinical and electrophysiological assessment for the diagnosis and staging of diabetic neuropathy.
Diabetes care 1994;17(11):1281-9.
1994: Martin J Stevens; J Dananberg; Eva L Feldman; S A Lattimer; M Kamijo; Thommey P Thomas; H Shindo; Anders A F Sima; Douglas A Greene
The linked roles of nitric oxide, aldose reductase and, (Na+,K+)-ATPase in the slowing of nerve conduction in the streptozotocin diabetic rat.
The Journal of clinical investigation 1994;94(2):853-9.
1994: Thommey P Thomas; Francesca Porcellati; K Kato; Martin J Stevens; W R Sherman; Douglas A Greene
Effects of glucose on sorbitol pathway activation, cellular redox, and metabolism of myo-inositol, phosphoinositide, and diacylglycerol in cultured human retinal pigment epithelial cells.
The Journal of clinical investigation 1994;93(6):2718-24.
1993: KC Allman; Martin J Stevens; Darryl Wieland; G D Hutchins; E R Wolfe; D A Greene; M Schwaiger
Noninvasive assessment of cardiac diabetic neuropathy by carbon-11 hydroxyephedrine and positron emission tomography.
Journal of the American College of Cardiology 1993;22(5):1425-32.
1993: Thommey P Thomas; Eva L Feldman; J Nakamura; K Kato; M Lien; Martin J Stevens; Douglas A Greene
Ambient glucose and aldose reductase-induced myo-inositol depletion modulate basal and carbachol-stimulated inositol phospholipid metabolism and diacylglycerol accumulation in human retinal pigment epithelial cells in culture.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(20):9712-6.
1993: Douglas A Greene; Anders A F Sima; Martin J Stevens; Eva L Feldman; Paul D Killen; D N Henry; Thommey P Thomas; J Dananberg; S A Lattimer
Aldose reductase inhibitors: an approach to the treatment of diabetic nerve damage.
Diabetes/metabolism reviews 1993;9(3):189-217.
1993: Martin J Stevens; D N Henry; Thommey P Thomas; Paul D Killen; Douglas A Greene
Aldose reductase gene expression and osmotic dysregulation in cultured human retinal pigment epithelial cells.
The American journal of physiology 1993;265(3 Pt 1):E428-38.
1993: Martin J Stevens; S A Lattimer; M Kamijo; C Van Huysen; Anders A F Sima; Douglas A Greene
Osmotically-induced nerve taurine depletion and the compatible osmolyte hypothesis in experimental diabetic neuropathy in the rat.
Diabetologia 1993;36(7):608-14.
1992: Douglas A Greene; Anders A F Sima; Martin J Stevens; Eva L Feldman; S A Lattimer
Complications: neuropathy, pathogenetic considerations.
Diabetes care 1992;15(12):1902-25.