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David Stewart

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Gerald S Falchook; Filip Janku; David J Stewart; Anne S Tsao; Christel C Bastida; Razelle Kurzrock
Non-small-cell lung cancer with HER2 exon 20 mutation: regression with dual HER2 inhibition and anti-VEGF combination treatment.
David J Stewart; Razelle Kurzrock
Fool's gold, lost treasures, and the randomized clinical trial.
Filip Janku; Donald A Berry; Jing Gong; Henrique A Parsons; David J Stewart; Razelle Kurzrock
Outcomes of phase II clinical trials with single-agent therapies in advanced/metastatic non-small cell lung cancer published between 2000 and 2009.

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2013: Gerald S Falchook; Filip Janku; David J Stewart; Anne S Tsao; Christel C Bastida; Razelle Kurzrock
Non-small-cell lung cancer with HER2 exon 20 mutation: regression with dual HER2 inhibition and anti-VEGF combination treatment.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2013;8(2):e19-20.
2013: David J Stewart; Razelle Kurzrock
Fool's gold, lost treasures, and the randomized clinical trial.
BMC cancer 2013;13():193.
2012: Filip Janku; Donald A Berry; Jing Gong; Henrique A Parsons; David J Stewart; Razelle Kurzrock
Outcomes of phase II clinical trials with single-agent therapies in advanced/metastatic non-small cell lung cancer published between 2000 and 2009.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(22):6356-63.
2012: Eric S Kim; J Jack Lee; David J Stewart; Stephen G Swisher; Ignacio I Wistuba; Chi-Wan Chow; Junya Fujimoto; Guangan He; Neda Kalhor; Zahid H Siddik
Tissue platinum concentration and tumor response in non-small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012;30(27):3345-52.
2012: Banibrata Sen; David J Stewart; Ximing Tang; Ignacio Wistuba; Heidi S Erickson; Hector Galindo; Tuhina Mazumdar; Shaohua Peng; Faye M Johnson
Kinase-impaired BRAF mutations in lung cancer confer sensitivity to dasatinib.
Science translational medicine 2012;4(136):136ra70.
2012: Maria Ines Nunez; David J Stewart; Milind Suraokar; Carmen Behrens; Wilbur Franklin; Wayne Hofstetter; Humam Kadara; Neda Kalhor; J Jack Lee; Heather Lin; Denise M Woods; Ignacio I Wistuba
High expression of folate receptor alpha in lung cancer correlates with adenocarcinoma histology and EGFR [corrected] mutation.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2012;7(5):833-40.
2012: Abujiang Pataer; Maria Gabriela Raso; Jack A Roth; David J Stewart; Stephen G Swisher; Ara A Vaporciyan; Ignacio I Wistuba; Carmen Behrens; Arlene M Correa; Jeremy J Erasmus; Neda Kalhor; Edward S Kim; J Jack Lee
Histopathologic response criteria predict survival of patients with resected lung cancer after neoadjuvant chemotherapy.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2012;7(5):825-32.
2012: Charles Lu; John D McMannis; Maria I Nunez; Rajagopal Ramesh; James M Reuben; Veerabhadran Baladandayuthapani; Jeremy J Erasmus; Elizabeth A Grimm; Marshall E Hicks; Gitanjali Jayachandran; Lin Ji; J Jack Lee; David J Stewart; Nancy S Templeton; Ignacio I Wistuba; Jack A Roth
Phase I clinical trial of systemically administered TUSC2(FUS1)-nanoparticles mediating functional gene transfer in humans.
PloS one 2012;7(4):e34833.
2011: Anne S Tsao; Ignacio I Wistuba; Hai T Tran; George R Blumenschein; Chusilp Charnsangavej; Frank V Fossella; Junya Fujimoto; Waun K Hong; Merrill S Kies; J Jack Lee; Suyu Liu; Edith M Marom; Vassiliki A Papadimitrakopoulou; David J Stewart
Phase II trials of imatinib mesylate and docetaxel in patients with metastatic non-small cell lung cancer and head and neck squamous cell carcinoma.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2011;6(12):2104-11.
2011: Li-E Wang; Ming Yin; Christopher I Amos; Qiong Dong; Kelly W Merriman; Margaret R Spitz; David J Stewart; Qingyi Wei
DNA repair capacity in peripheral lymphocytes predicts survival of patients with non-small-cell lung cancer treated with first-line platinum-based chemotherapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(31):4121-8.
2011: David J Stewart; Jeremy J Erasmus
Erlotinib accumulation in brain metastases from non-small cell lung cancer: visualization by positron emission tomography in a patient harboring a mutation in the epidermal growth factor receptor.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2011;6(7):1149-51.
2011: Xifeng Wu; Yuanqing Ye; Rafael Rosell; Christopher I Amos; David J Stewart; Michelle A T Hildebrandt; Jack A Roth; John D Minna; Jian Gu; Jie Lin; Shama C Buch; Tomoko Nukui; Jose Luis Ramirez Serrano; Miquel Taron; Adrian Cassidy; Charles Lu; Joe Y Chang; Scott M Lippman; Waun Ki Hong; Margaret R Spitz; Marjorie Romkes; Ping Yang
Genome-wide association study of survival in non-small cell lung cancer patients receiving platinum-based chemotherapy.
Journal of the National Cancer Institute 2011;103(10):817-25.
2011: David J Stewart
Chemotherapy dose intensity and survival in non-small cell lung cancer.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2011;6(5):971.
2011: Jan A Burger; David J Stewart; Ori Wald; Amnon Peled
Potential of CXCR4 antagonists for the treatment of metastatic lung cancer.
Expert review of anticancer therapy 2011;11(4):621-30.
2011: David J Stewart; Carmen Behrens; Jack Roth; Ignacio I Wistuba
Exponential decay nonlinear regression analysis of patient survival curves: preliminary assessment in non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands) 2011;71(2):217-23.
2011: Xia Pu; Michelle A T Hildebrandt; Charles Lu; Jie Lin; David J Stewart; Yuanqing Ye; Jian Gu; Margaret R Spitz; Xifeng Wu
PI3K/PTEN/AKT/mTOR pathway genetic variation predicts toxicity and distant progression in lung cancer patients receiving platinum-based chemotherapy.
Lung cancer (Amsterdam, Netherlands) 2011;71(1):82-8.
2010: Faye M Johnson; B Nebiyou Bekele; Lei Feng; Ignacio Wistuba; Xi Ming Tang; Hai T Tran; Jeremy J Erasmus; Li-Ling Hwang; Naoko Takebe; George R Blumenschein; Scott M Lippman; David J Stewart
Phase II study of dasatinib in patients with advanced non-small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(30):4609-15.
2010: David J Stewart
Tumor and host factors that may limit efficacy of chemotherapy in non-small cell and small cell lung cancer.
Critical reviews in oncology/hematology 2010;75(3):173-234.
2010: Filip Janku; David J Stewart; Razelle Kurzrock
Targeted therapy in non-small-cell lung cancer--is it becoming a reality?
Nature reviews. Clinical oncology 2010;7(7):401-14.
2010: David J Stewart; Simon N Whitney; Razelle Kurzrock
Equipoise lost: ethics, costs, and the regulation of cancer clinical research.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(17):2925-35.
2010: William N William; James Uyeki; Faye M Johnson; Lei Feng; Beverly O Peeples; Frank V Fossella; Daniel D Karp; George R Blumenschein; David J Stewart; Bonnie S Glisson
Weekly alternating therapy with irinotecan plus cisplatin and etoposide plus cisplatin in the treatment of patients with extensive small cell lung carcinoma.
Cancer 2010;116(10):2409-15.
2010: Michelle A T Hildebrandt; Ritsuko Komaki; Zhongxing Liao; Jian Gu; Joe Y Chang; Yuanqing Ye; Charles Lu; David J Stewart; John D Minna; Jack A Roth; Scott M Lippman; James D Cox; Waun Ki Hong; Margaret R Spitz; Xifeng Wu
Genetic variants in inflammation-related genes are associated with radiation-induced toxicity following treatment for non-small cell lung cancer.
PloS one 2010;5(8):e12402.
2009: Apostolia-Maria Tsimberidou; Fadi Braiteh; David J Stewart; Razelle Kurzrock
Ultimate fate of oncology drugs approved by the us food and drug administration without a randomized Trial.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(36):6243-50.
2009: George R Blumenschein; Ulrich Gatzemeier; Frank V Fossella; David J Stewart; Lisa Cupit; Frank Cihon; James O'Leary; Martin Reck
Phase II, multicenter, uncontrolled trial of single-agent sorafenib in patients with relapsed or refractory, advanced non-small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(26):4274-80.
2009: Yun Oh; S Taylor; B Nebiyou Bekele; J Matthew Debnam; Pamela K Allen; Dima Suki; Raymond Sawaya; Ritsuko Komaki; David J Stewart; Daniel D Karp
Number of metastatic sites is a strong predictor of survival in patients with nonsmall cell lung cancer with or without brain metastases.
Cancer 2009;115(13):2930-8.
2009: David J Stewart; Jean-Pierre J Issa; Razelle Kurzrock; Maria I Nunez; Jaroslav Jelinek; David Hong; Yasuhiro Oki; Zhong Guo; Sanjay Gupta; Ignacio I Wistuba
Decitabine effect on tumor global DNA methylation and other parameters in a phase I trial in refractory solid tumors and lymphomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(11):3881-8.
2008: J Xing; David J Stewart; Jian Gu; C Lu; Margaret R Spitz; Xifeng Wu
Expression of methylation-related genes is associated with overall survival in patients with non-small cell lung cancer.
British journal of cancer 2008;98(10):1716-22.
2008: Yun Oh; David J Stewart
Systemic therapy for lung cancer brain metastases: a rationale for clinical trials.
Oncology (Williston Park, N.Y.) 2008;22(2):168-78; discussion 178, 183, 188 passim.
2007: Hushan Yang; Margaret R Spitz; David J Stewart; Charles Lu; Ivan P Gorlov; Xifeng Wu
ATM sequence variants associate with susceptibility to non-small cell lung cancer.
International journal of cancer. Journal international du cancer 2007;121(10):2254-9.
2007: Wei Wang; Margaret R Spitz; Hushan Yang; Charles Lu; David J Stewart; Xifeng Wu
Genetic variants in cell cycle control pathway confer susceptibility to lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(19):5974-81.
2007: William N William; Ralph G Zinner; Daniel D Karp; Yun W Oh; Bonnie S Glisson; See-Chun Phan; David J Stewart
Phase I trial of motexafin gadolinium in combination with docetaxel and cisplatin for the treatment of non-small cell lung cancer.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2007;2(8):745-50.
2007: Jinliang Xing; Margaret R Spitz; Charles Lu; Hua Zhao; Hushan Yang; Wei Wang; David J Stewart; Xifeng Wu
Deficient G2-M and S checkpoints are associated with increased lung cancer risk: a case-control analysis.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2007;16(7):1517-22.
2007: David J Stewart
Mechanisms of resistance to cisplatin and carboplatin.
Critical reviews in oncology/hematology 2007;63(1):12-31.
2007: David J Stewart; Gabriela Chiritescu; Simone Dahrouge; Srabani Banerjee; Eva Tomiak
Chemotherapy dose--response relationships in non-small cell lung cancer and implied resistance mechanisms.
Cancer treatment reviews 2007;33(2):101-37.
2007: Ozden Altundag; David J Stewart; Frank V Fossella; Gregory D Ayers; Wei Wei; Xian Zhou; Ralph G Zinner
Many patients 80 years and older with advanced non-small cell lung cancer (NSCLC) can tolerate chemotherapy.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2007;2(2):141-6.
2005: Reginald F Munden; Stephen S Swisher; Craig W Stevens; David J Stewart
Imaging of the patient with non-small cell lung cancer.
Radiology 2005;237(3):803-18.
2005: Rakesh Goel; E Chouinard; David J Stewart; SD Huan; Hal Hirte; S Stafford; B Waterfield; J Roach; Chetan Lathia; V Agarwal; R Humphrey; Wendy Walsh; Sarah Matthews; Lesley Seymour
An NCIC CTG phase I/pharmacokinetic study of the matrix metalloproteinase and angiogenesis inhibitor BAY 12-9566 in combination with 5-fluorouracil/leucovorin.
Investigational new drugs 2005;23(1):63-71.
2004: David J Stewart; Eva Tomiak; Farid M Shamji; Donna E Maziak; Peter MacLeod
Phase II study of alternating chemotherapy regimens for advanced non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands) 2004;44(2):241-9.
2004: David J Stewart
Update on the role of topotecan in the treatment of non-small cell lung cancer.
The oncologist 2004;9 Suppl 6():43-52.
2004: David J Stewart
Topotecan in the first-line treatment of small cell lung cancer.
The oncologist 2004;9 Suppl 6():33-42.
2004: David J Stewart
Foreword--new directions for topotecan in lung cancer treatment.
The oncologist 2004;9 Suppl 6():1-3.
2003: David J Stewart; Ross C Donehower; Elizabeth A Eisenhauer; Nancy Wainman; A K Shah; Claire Bonfils; A Robert MacLeod; Jeffrey M Besterman; Gregory K Reid
A phase I pharmacokinetic and pharmacodynamic study of the DNA methyltransferase 1 inhibitor MG98 administered twice weekly.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2003;14(5):766-74.
2002: Mark Adel Nassim; Farshad H Shirazi; Christine M Cripps; Shereeni Veerasinghan; Matshela J Molepo; Mihail Obrocea; Diedre Redmond; Susan Bates; Diane Fry; David J Stewart; Rakesh Goel
An HPLC method for the measurement of 5-fluorouracil in human plasma with a low detection limit and a high extraction yield.
International journal of molecular medicine 2002;10(4):513-6.
2001: Farshad H Shirazi; G Bahrami; David J Stewart; Eva Tomiak; F Delorme; D Noel; Rakesh Goel
A rapid reversed phase high performance liquid chromatographic method for determination of etoposide (VP-16) in human plasma.
Journal of pharmaceutical and biomedical analysis 2001;25(3-4):353-6.
2000: D Hao; SD Huan; David J Stewart; Roanne J Segal; JC Yau
A pilot study of low dose hydroxyurea as a novel resistance modulator in metastatic renal cell cancer.
Journal of chemotherapy (Florence, Italy) 2000;12(4):360-6.
2000: JC Yau; Stan Gertler; J Hanson; S Verma; L J Grimard; S T Malik; Ibrahim M. Aref; PW Cross; Eva Tomiak; David J Stewart; D A St Cyr; SD Huan
A phase III study of high-dose intensification without hematopoietic progenitor cells support for patients with high-risk primary breast carcinoma.
American journal of clinical oncology 2000;23(3):292-6.
2000: SD Huan; R B Natale; David J Stewart; G P Sartiano; P J Stella; J D Roberts; A L Symes; M Finizio
A multicenter phase II trial of losoxantrone (DuP-941) in hormone-refractory metastatic prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(4):1333-6.
2000: Stan Gertler; D MacDonald; M Goodyear; Peter A Forsyth; David J Stewart; K Belanger; J Perry; D Fulton; W Steward; Nancy Wainman; Lesley Seymour
NCIC-CTG phase II study of gemcitabine in patients with malignant glioma (IND.94).
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2000;11(3):315-8.
2000: R Donker; David J Stewart; Simone Dahrouge; William K Evans; Farid M Shamji; Donna E Maziak; Eva Tomiak
Clinical characteristics and the impact of surgery and chemotherapy on survival of patients with advanced and metastatic bronchioloalveolar carcinoma: a retrospective study.
Clinical lung cancer 2000;1(3):211-5; discussion 216.
1999: SD Huan; David J Stewart; S E Aitken; R Segal; JC Yau
Combination of epirubicin and cisplatin in hormone-refractory metastatic prostate cancer.
American journal of clinical oncology 1999;22(5):471-4.
1999: David J Stewart; Rakesh Goel; Stan Gertler; SD Huan; Eva Tomiak; JC Yau; Christine M Cripps; William K Evans
Concurrent use of multiple low dose chemotherapy agents with differing mechanisms of action as a strategy vs passive resistance: A pilot study.
International journal of oncology 1999;15(4):693-9.
1999: David J Stewart; Simone Dahrouge; Douglas Coyle; William K Evans
Costs of treating and preventing nausea and vomiting in patients receiving chemotherapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1999;17(1):344-51.
1999: Q Chau; David J Stewart
Cisplatin efflux, binding and intracellular pH in the HTB56 human lung adenocarcinoma cell line and the E-8/0.7 cisplatin-resistant variant.
Cancer chemotherapy and pharmacology 1999;44(3):193-202.
1999: C Lochrin; Glenwood Goss; David J Stewart; PW Cross; OO Agboola; Simone Dahrouge; Eva Tomiak; William K Evans
Concurrent chemotherapy with hyperfractionated accelerated thoracic irradiation in stage III non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands) 1999;23(1):19-30.
1998: Craig C Earle; David J Stewart; Y Cormier; William K Evans; Stan Gertler; C Mihalcioiu; P D Walde
A phase I study of gemcitabine/cisplatin/etoposide in the treatment of small-cell lung cancer.
Lung cancer (Amsterdam, Netherlands) 1998;22(3):235-41.
1998: Mihail Obrocea; Mark Adel Nassim; M J Molepo; Farshad H Shirazi; G Gallant; H Dulude; mark vincent; David J Stewart; Rakesh Goel
In vitro carboplatin-mesna interaction in aqueous solution, human plasma and urine.
Oncology reports 1998;5(6):1493-8.
1998: M R Rouini; A Lotfolahi; David J Stewart; J M Molepo; Farshad H Shirazi; J C Vergniol; Eva Tomiak; F Delorme; L Vernillet; M Giguere; Rakesh Goel
A rapid reversed phase high performance liquid chromatographic method for the determination of docetaxel (Taxotere) in human plasma using a column switching technique.
Journal of pharmaceutical and biomedical analysis 1998;17(8):1243-7.
1998: Mark Adel Nassim; M R Rouini; M C Cripps; Farshad H Shirazi; S Veerasinghan; J M Molepo; Mihail Obrocea; D Redmond; S Bates; D Fry; David J Stewart; Rakesh Goel
Effects of PALA on the pharmacokinetics of 5-fluorouracil.
Oncology reports 1998;5(1):217-21.
1997: William K Evans; Craig C Earle; David J Stewart; Simone Dahrouge; Eva Tomiak; Glenwood Goss; DM Logan; Rakesh Goel; Stan Gertler; H Dulude
Phase II study of a one hour paclitaxel infusion in combination with carboplatin for advanced non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands) 1997;18(1):83-94.
1997: David J Stewart; Simone Dahrouge
Mitoxantrone in the treatment of metastatic transitional cell carcinoma of the prostate. A case report.
American journal of clinical oncology 1997;20(4):381-2.
1997: David J Stewart; William K Evans; F A Shepherd; K S Wilson; K I Pritchard; M E Trudeau; J J Wilson; K Martz
Cyclophosphamide and fluorouracil combined with mitoxantrone versus doxorubicin for breast cancer: superiority of doxorubicin.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1997;15(5):1897-905.
1997: David J Stewart; Simone Dahrouge; OO Agboola; A Girard
Cranial radiation and concomitant cisplatin and mitomycin-C plus resistance modulators for malignant gliomas.
Journal of neuro-oncology 1997;32(2):161-8.
1997: SD Huan; R G Gerridzen; JC Yau; David J Stewart
Antiandrogen withdrawal syndrome with nilutamide.
Urology 1997;49(4):632-4.
1997: David J Stewart; Rakesh Goel; M C Cripps; SD Huan; JC Yau; S Verma
Multiple resistance modulators combined with carboplatin for resistant malignancies: a pilot study.
Investigational new drugs 1997;15(4):267-77.
1997: David J Stewart; M C Cripps; Rakesh Goel; Simone Dahrouge; JC Yau; Eva Tomiak; SD Huan; K Soltys; A Prosser; R A Davies
Pilot study of multiple chemotherapy resistance modulators plus epirubicin in the treatment of resistant malignancies.
Cancer chemotherapy and pharmacology 1997;41(1):1-8.
1997: David J Stewart; C S Dulberg; N Z Mikhael; M D Redmond; V A Montpetit; R Goel
Association of cisplatin nephrotoxicity with patient characteristics and cisplatin administration methods.
Cancer chemotherapy and pharmacology 1997;40(4):293-308.
1997: J Mathews; Rakesh Goel; W K Evans; Farid M Shamji; David J Stewart
Arterial occlusion in patients with peripheral vascular disease treated with platinum-based regimens for lung cancer.
Cancer chemotherapy and pharmacology 1997;40(1):19-22.
1996: SD Huan; JC Yau; Eva Tomiak; Rakesh Goel; C Cripps; Stan Gertler; I A Prosser; David J Stewart
Hydroxyurea did not enhance the clinical response to vinblastine in patients with anthracycline-resistant metastatic breast cancer.
Tumori 1996;82(6):576-8.
1996: Farshad H Shirazi; J M Molepo; David J Stewart; Cheng E Ng; G P Raaphorst; Rakesh Goel
Cytotoxicity, accumulation, and efflux of cisplatin and its metabolites in human ovarian carcinoma cells.
Toxicology and applied pharmacology 1996;140(2):211-8.
1996: David J Stewart; Eva Tomiak; Glenwood Goss; Stan Gertler; D Logan; SD Huan; JC Yau; H Dulude; William K Evans
Paclitaxel plus hydroxyurea as second line therapy for non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands) 1996;15(1):115-23.
1996: S Dent; Libni Eapen; A Girard; H Hugenholtz; V DaSilva; David J Stewart
PROMACE-MOPP and intrathecal chemotherapy for CNS lymphomas.
Journal of neuro-oncology 1996;28(1):25-30.
1996: K M Brière; Rakesh Goel; Farshad H Shirazi; David J Stewart; C P Smith
The integrity of cisplatin in aqueous and plasma ultrafiltrate media studied by 195Pt and 15N nuclear magnetic resonance.
Cancer chemotherapy and pharmacology 1996;37(6):518-24.
1995: K D Taylor; Rakesh Goel; Farshad H Shirazi; M Molepo; P Popovic; David J Stewart; P T Wong
Pressure tuning infrared spectroscopic study of cisplatin-induced structural changes in a phosphatidylserine model membrane.
British journal of cancer 1995;72(6):1400-5.
1995: SD Huan; S E Aitken; David J Stewart
A phase II study of 5-fluorouracil and high dose folinic acid in cisplatin-refractory metastatic bladder cancer.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1995;6(8):836-7.
1995: David J Stewart; R Belanger; R S Benjamin
Prolonged disease-free survival following surgical debulking and high-dose cisplatin/doxorubicin in a patient with bulky metastases from giant cell tumor of bone refractory to "standard" chemotherapy.
American journal of clinical oncology 1995;18(2):144-8.
1995: David J Stewart; Simone Dahrouge; K M Soltys; William K Evans
A phase II study of 5-fluorouracil plus high-dose folinic acid in the treatment of recurrent small cell lung cancer.
American journal of clinical oncology 1995;18(2):130-2.
1995: William K Evans; A Radwi; Eva Tomiak; D M Logan; H Martins; David J Stewart; Glenwood Goss; Jean Maroun; Simone Dahrouge
Oral etoposide and carboplatin. Effective therapy for elderly patients with small cell lung cancer.
American journal of clinical oncology 1995;18(2):149-55.
1995: David J Stewart; J M Molepo; R M Green; V A Montpetit; H Hugenholtz; A Lamothe; N Z Mikhael; M D Redmond; M Gadia; Rakesh Goel
Factors affecting platinum concentrations in human surgical tumour specimens after cisplatin.
British journal of cancer 1995;71(3):598-604.
1995: David J Stewart; Simone Dahrouge; K Soltys
A phase II study of 5-fluorouracil plus folinic acid in malignant gliomas in adults.
Journal of neuro-oncology 1995;23(3):249-52.
1995: David J Stewart; Simone Dahrouge
Response of brain metastases from breast cancer to megestrol acetate: a case report.
Journal of neuro-oncology 1995;24(3):299-301.
1995: David J Stewart; Simone Dahrouge; M Wee; S Aitken; H Hugenholtz
Intraarterial cisplatin plus intravenous doxorubicin for inoperable recurrent meningiomas.
Journal of neuro-oncology 1995;24(2):189-94.
1995: David J Stewart; L R Morgan; S Verma; Jean Maroun; M Thibault
Pharmacology, relative bioavailability, and toxicity of three different oral cyclophosphamide preparations in a randomized, cross-over study.
Investigational new drugs 1995;13(1):99-107.
1994: SD Huan; S E Aitken; David J Stewart
5-fluorouracil and high dose folinic acid in hormone-refractory metastatic prostate cancer: a phase II study.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1994;5(7):644-5.
1994: David J Stewart; Stan Gertler; A Tomiak; F Shamji; Rakesh Goel; William K Evans
High dose doxorubicin plus cisplatin in the treatment of unresectable mesotheliomas: report of four cases.
Lung cancer (Amsterdam, Netherlands) 1994;11(3-4):251-8.
1994: David J Stewart; William K Evans; D Logan
Addition of pentoxifylline plus nifedipine to chemotherapy in patients with cisplatin-resistant cancers of the lung and other sites.
American journal of clinical oncology 1994;17(4):313-6.
1994: David J Stewart; J M Molepo; Libni Eapen; V A Montpetit; Rakesh Goel; P T Wong; P Popovic; K D Taylor; G P Raaphorst
Cisplatin and radiation in the treatment of tumors of the central nervous system: pharmacological considerations and results of early studies.
International journal of radiation oncology, biology, physics 1994;28(2):531-42.
1994: William K Evans; David J Stewart; Frances A Shepherd; D Logan; Glenwood Goss; Jean Maroun; R Wierzbicki; E Warner; Jean Latreille; Simone Dahrouge
VP-16, ifosfamide and cisplatin (VIP) for extensive small cell lung cancer.
European journal of cancer (Oxford, England : 1990) 1994;30A(3):299-303.
1994: David J Stewart; C Dulberg; J M Molepo; N Z Mikhael; V A Montpetit; M D Redmond; Rakesh Goel
Factors affecting human autopsy kidney-cortex and kidney-medulla platinum concentrations after cisplatin administration.
Cancer chemotherapy and pharmacology 1994;34(1):14-22.
1994: David J Stewart
A critique of the role of the blood-brain barrier in the chemotherapy of human brain tumors.
Journal of neuro-oncology 1994;20(2):121-39.
1993: D A Stewart; David J Stewart; K T Mai
Active chemotherapy for metastatic stromal cell tumor of the testis.
Urology 1993;42(6):732-4.
1993: David J Stewart; D Grewaal; R M Green; N Mikhael; Rakesh Goel; V A Montpetit; M D Redmond
Concentrations of doxorubicin and its metabolites in human autopsy heart and other tissues.
Anticancer research 1993;13(6A):1945-52.
1993: David J Stewart; Z Grahovac; H Hugenholtz; V DaSilva; M T Richard; B Benoit; G Belanger; N Russell
Feasibility study of intraarterial vs intravenous cisplatin, BCNU, and teniposide combined with systemic cisplatin, teniposide, cytosine arabinoside, glycerol and mannitol in the treatment of primary and metastatic brain tumors.
Journal of neuro-oncology 1993;17(1):71-9.
1993: David J Stewart; M C Cripps; H Fingert; A Lamothe; G Laframboise; J Gerin-Lajoie
Cisplatin, cytosine arabinoside, and pentoxifylline in the treatment of squamous cell carcinoma of the head and neck.
American journal of clinical oncology 1993;16(2):123-6.
1993: David J Stewart; M C Cripps; A Lamothe; G Laframboise; Paul F Odell; J Gerin-Lajoie
Doxorubicin plus metronidazole in the treatment of recurrent or metastatic squamous cell carcinoma of the head and neck.
American journal of clinical oncology 1993;16(2):113-6.
1993: David J Stewart; Libni Eapen; A Girard; S Verma; P Genest; W K Evans
Phase II study of lonidamine plus radiotherapy in the treatment of brain metastases.
Journal of neuro-oncology 1993;15(1):19-22.
1993: David J Stewart; D Grewaal; R M Green; Rakesh Goel; N Mikhael; V A Montpetit; D Redmond; R Earhart
Human autopsy-tissue distribution of menogaril and its metabolites.
Cancer chemotherapy and pharmacology 1993;32(5):373-8.
1993: David J Stewart; D Grewaal; M D Redmond; N Z Mikhael; V A Montpetit; Rakesh Goel; R M Green
Human autopsy tissue distribution of the epipodophyllotoxins etoposide and teniposide.
Cancer chemotherapy and pharmacology 1993;32(5):368-72.
1992: David J Stewart; H Hugenholtz; V F DaSilva; B G Benoit; M T Richard; S Verma; R Earhart; L Robillard
Phase II study of weekly intravenous menogaril in the treatment of recurrent astrocytomas in adults.
Journal of neuro-oncology 1992;13(2):183-8.
1992: R W Gregg; J M Molepo; V J Monpetit; N Z Mikael; D Redmond; M Gadia; David J Stewart
Cisplatin neurotoxicity: the relationship between dosage, time, and platinum concentration in neurologic tissues, and morphologic evidence of toxicity.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1992;10(5):795-803.
1992: David J Stewart; S E Aitken; S Verma; Jean Maroun; L Robillard; M Touchie; I A Prosser; R Earhart
Phase I study of oral menogaril administered daily for 14 consecutive days.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1992;3(5):401-3.
1992: David J Stewart; J M Belanger; Z Grahovac; S Curuvija; L R Gionet; S E Aitken; H Hugenholtz; B G Benoit; V F DaSilva
Phase I study of intracarotid administration of carboplatin.
Neurosurgery 1992;30(4):512-6; discussion 516-7.
1992: David J Stewart; Elizabeth A Eisenhauer; J Skillings; K I Pritchard; R Buckman; T VAndenberg; S Verma; S Aitken; B Norris
Phase II study of oral menogaril as first line chemotherapy for advanced breast cancer: a National Cancer Institute of Canada Clinical Trials Group study.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1992;3(3):201-4.
1991: David J Stewart; S E Aitken; A H Irvine; D E Moors; N G Futter
Phase II study of lonidamine in metastatic prostatic carcinoma.
Investigational new drugs 1991;9(4):343-4.
1991: David J Stewart; D Grewaal; R M Green; S Verma; Jean Maroun; D Redmond; L Robillard; S Gupta
Bioavailability and pharmacology of oral idarubicin.
Cancer chemotherapy and pharmacology 1991;27(4):308-14.
1990: David J Stewart; S Verma; Jean Maroun; L Robillard; D J Perrault; V Young; S Gupta; B Fontaine
Phase I study of idarubicin administered orally on a daily x 3 schedule.
Investigational new drugs 1990;8(3):275-81.
1990: David J Stewart; R Green; N Futter; W Walsh; D McKay; S Verma; Jean Maroun; D Redmond
Phase I and pharmacology study of intravesical mitoxantrone for recurrent superficial bladder tumors.
The Journal of urology 1990;143(4):714-6.
1990: S Verma; David J Stewart; Jean Maroun; Rama Nair
A randomized phase II study of cisplatin alone versus cisplatin plus disulfiram.
American journal of clinical oncology 1990;13(2):119-24.
1990: David J Stewart; S Verma; Jean Maroun; L Robillard; R H Earhart
Phase I study of oral menogaril administered on a once weekly schedule.
Investigational new drugs 1990;8(1):43-52.
1990: Jean Maroun; David J Stewart
Phase I study of tiazofurin (2-beta-D-ribofuranosylthiazole-4-carboxamide, NSC 286193).
Investigational new drugs 1990;8 Suppl 1():S33-9.
1990: William K Evans; R Wierzbicki; Frances A Shepherd; J Rusthoven; David J Stewart; S E Aitken; Jean Maroun; A Ezzat
5-Fluorouracil with folinic acid is not effective against metastatic adenocarcinoma of the lung.
Cancer investigation 1990;8(3-4):345-9.
1989: David J Stewart; Jean Maroun; S Verma; D Perrault; R H Earhart
Phase I study of weekly intravenous administration of menogaril to adults with solid tumors.
American journal of clinical oncology 1989;12(6):511-8.
1989: David J Stewart
Pros and cons of intra-arterial chemotherapy.
Oncology (Williston Park, N.Y.) 1989;3(10):20-6; discussion 26-7, 30, 32.
1989: David J Stewart
The role of chemotherapy in the treatment of gliomas in adults.
Cancer treatment reviews 1989;16(3):129-60.
1989: David J Stewart; W K Evans
Non-chemotherapeutic agents that potentiate chemotherapy efficacy.
Cancer treatment reviews 1989;16(1):1-40.
1988: David J Stewart; N Z Mikhael; Rama Nair; S Kacew; V Montpetit; A Nanji; Jean Maroun; K Howard
Platinum concentrations in human autopsy tumor samples.
American journal of clinical oncology 1988;11(2):152-8.
1988: R M Green; David J Stewart; H Hugenholtz; M T Richard; M Thibault; V Montpetit
Human central nervous system and plasma pharmacology of mitoxantrone.
Journal of neuro-oncology 1988;6(1):75-83.
1987: David J Stewart; S Verma; Jean Maroun
Phase I study of the combination of disulfiram with cisplatin.
American journal of clinical oncology 1987;10(6):517-9.
1987: David J Stewart; N Futter; A Irvine; C Danjoux; D Moors
Mitomycin-C and metronidazole in the treatment of advanced renal-cell carcinoma.
American journal of clinical oncology 1987;10(6):520-2.
1987: David J Stewart; Z Grahovac; H Hugenholtz; N A Russell; M T Richard; B G Benoit; M D Riding; C Danjoux; Jean Maroun
Intraarterial mitomycin-C for recurrent brain metastases.
American journal of clinical oncology 1987;10(5):432-6.
1987: David J Stewart; D J Perrault; Jean Maroun; B M Lefebvre
Combined mitoxantrone plus doxorubicin in the treatment of breast cancer.
American journal of clinical oncology 1987;10(4):335-40.
1987: David J Stewart; C Cripps; Jean Maroun
Phase II study of high-dose mitoxantrone in the treatment of recurrent squamous cell carcinoma of the head and neck.
American journal of clinical oncology 1987;10(4):307-9.
1987: David J Stewart; Libni Eapen; W E Hirte; N G Futter; D E Moors; P G Murphy; A H Irvine; P Genest; D E McKay; W K Evans
Intra-arterial cisplatin for bladder cancer.
The Journal of urology 1987;138(2):302-5.
1987: David J Stewart; Z Grahovac; H Hugenholtz; N Russell; M Richard; B Benoit
Combined intraarterial and systemic chemotherapy for intracerebral tumors.
Neurosurgery 1987;21(2):207-14.
1987: David J Stewart; H Hugenholtz; V DaSilva; B Benoit; M Richard; N Russell; Jean Maroun; S Verma
Cytosine arabinoside plus cisplatin and other drugs as chemotherapy for gliomas.
Seminars in oncology 1987;14(2 Suppl 1):110-5.
1987: David J Stewart; Z Grahovac; N A Russel; H Hugenholtz; S Gupta; B C Benoit; M T Richard; Jean Maroun; H S Hopkins; L Locke
Phase I study of intracarotid PCNU.
Journal of neuro-oncology 1987;5(3):245-50.
1987: L Goumnerova; M T Richard; D Addison; V Montpetit; David J Stewart
Intracarotid infusion of PCNU (NSC: 95466): preclinical toxicological study in dogs.
Journal of neuro-oncology 1987;5(3):205-9.
1987: David J Stewart; Jean Maroun; H Hugenholtz; B Benoit; A Girard; M Richard; N Russell; L Huebsch; J Drouin
Combined intraommaya methotrexate, cytosine arabinoside, hydrocortisone and thio-TEPA for meningeal involvement by malignancies.
Journal of neuro-oncology 1987;5(4):315-22.
1986: David J Stewart; R M Green; N Z Mikhael; V Montpetit; M Thibault; Jean Maroun
Human autopsy tissue concentrations of mitoxantrone.
Cancer treatment reports 1986;70(11):1255-61.
1986: Jean Maroun; A Maksymiuk; Elizabeth Eisenhauer; David J Stewart; V Young; Joseph L Pater
Phase II study of acivicin in non-small cell lung cancer: a National Cancer Institute of Canada Study.
Cancer treatment reports 1986;70(11):1327-8.
1986: David J Stewart; Jean Maroun; W Hirte; B Lefebvre; V Young; A F Crook; R Heringer; R McDermott
Vinblastine, adriamycin, and cyclophosphamide in the treatment of adenocarcinoma of the breast.
American journal of clinical oncology 1986;9(3):217-22.
1986: David J Stewart; Jean Maroun; G Laframboise; J Gerin-Lajoie
Cisplatin plus cytosine arabinoside in the treatment of squamous cell carcinoma of the head and neck.
American journal of clinical oncology 1986;9(3):200-3.
1986: David J Stewart; Jean Maroun; B Lefebvre; R Heringer
Neurotoxicity and efficacy of combined vinca alkaloids in breast cancer.
Cancer treatment reports 1986;70(5):571-3.
1986: David J Stewart; Jean Maroun; C Cripps; V Young; G Laframboise; J Gerin-Lajoie
Methotrexate and 5-fluorouracil in the treatment of squamous and other carcinomas of the head and neck.
Cancer chemotherapy and pharmacology 1986;17(1):91-4.
1985: David J Stewart; N Z Mikhael; A A Nanji; Rama Nair; S Kacew; K Howard; W Hirte; Jean Maroun
Renal and hepatic concentrations of platinum: relationship to cisplatin time, dose, and nephrotoxicity.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1985;3(9):1251-6.
1985: David J Stewart; D Nundy; J A Maroun; L Tetreault; J Prior
Bioavailability, pharmacokinetics, and clinical effects of an oral preparation of etoposide.
Cancer treatment reports 1985;69(3):269-73.
1985: David J Stewart; Jean Maroun; B Lefebvre; R Heringer; A F Crook
Mitomycin-C plus metronidazole in advanced carcinoma of the breast.
Breast cancer research and treatment 1985;5(2):189-94.
1984: David J Stewart; Z Grahovac; B Benoit; D Addison; M T Richard; J Dennery; H Hugenholtz; N Russell; E Peterson; Jean Maroun
Intracarotid chemotherapy with a combination of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU), cis-diaminedichloroplatinum (cisplatin), and 4'-O-demethyl-1-O-(4,6-O-2-thenylidene-beta-D-glucopyranosyl) epipodophyllotoxin (VM-26) in the treatment of primary and metastatic brain tumors.
Neurosurgery 1984;15(6):828-33.
1984: Jean Maroun; A L Fields; J L Pater; David J Stewart; C Cripps; Elizabeth Eisenhauer
Phase II study of acivicin in colorectal carcinoma: a National Cancer Institute of Canada study.
Cancer treatment reports 1984;68(9):1121-3.
1984: David J Stewart; Jean Maroun; W Hirte; D Perrault; L Stolbach; C Cripps; B Lefebvre
A randomized comparison of cyclophosphamide-mitoxantrone-5-fluorouracil v cyclophosphamide-doxorubicin-5-fluorouracil in advanced breast cancer: preliminary observations.
Seminars in oncology 1984;11(3 Suppl 1):23-7.
1984: David J Stewart; N Futter; Jean Maroun; P Murphy; D McKay; P Rasuli
Intra-arterial cisplatin treatment of unresectable or medically inoperable invasive carcinoma of the bladder.
The Journal of urology 1984;131(2):258-61.
1984: David J Stewart; M T Richard; H Hugenholtz; J Dennery; D Nundy; J Prior; V Montpetit; H S Hopkins
Penetration of teniposide (VM-26) into human intracerebral tumors. Preliminary observations on the effect of tumor type, rate of drug infusion and prior treatment with amphotericin B or oral glycerol.
Journal of neuro-oncology 1984;2(4):315-24.
1984: David J Stewart; M T Richard; H Hugenholtz; J M Dennery; R Belanger; J Gerin-Lajoie; V Montpetit; D Nundy; J Prior; H S Hopkins
Penetration of VP-16 (etoposide) into human intracerebral and extracerebral tumors.
Journal of neuro-oncology 1984;2(2):133-9.
1984: David J Stewart; B Benoit; M T Richard; H Hugenholtz; J Dennery; N Russell; E Peterson; Z Grahovac; G Belanger; Jean Maroun
Treatment of malignant gliomas in adults with BCNU plus metronidazole.
Journal of neuro-oncology 1984;2(1):53-8.
1984: David J Stewart; M T Richard; B Benoit; H Hugenholtz; N Russell; J Dennery; E Peterson; Z Grahovac; G Belanger; S Aitkens
Cisplatin plus cytosine arabinoside in adults with malignant gliomas.
Journal of neuro-oncology 1984;2(1):29-34.
1983: David J Stewart; Jean Maroun; V Young; A F Crook; H S Hopkins; R C Yan; M T Richard; H Hugenholtz; R Bélanger; R Heringer
Feasibility study of combining metronidazole with chemotherapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1983;1(1):17-23.