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Heinrich Sticht

Research Profile

Genes & Molecular Sequences

Amino Acid Sequences

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Nuclear Magnetic Resonance, Biomolecular

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TOP 3
Myriam Scherer; Victoria Otto; Nina Reuter; Heinrich Sticht; Nadine Wagenknecht; Thomas Stamminger
Small ubiquitin-related modifier (SUMO) pathway-mediated enhancement of human cytomegalovirus replication correlates with a recruitment of SUMO-1/3 proteins to viral replication compartments.
Martin H Griessl; Michael Hensel; Kristin Kassler; Regina Ritter; Tilman E Schäffer; Benedikt Schmid; Heinrich Sticht; York-Dieter Stierhof; Karina U Sturm; Carolin Wagner; Britta Barlag; Christoph Braunsmann; Claudia Danzer; Yves A Muller
Structural Insight into the Giant Ca(2+)-Binding Adhesin SiiE: Implications for the Adhesion of Salmonella enterica to Polarized Epithelial Cells.
Sarah Jill de Jong; Fabian Giehler; Arnd Kieser; Heinrich Sticht; Jens-Christian Albrecht; Brigitte Biesinger
Noncanonical NF-κB activation by the oncoprotein Tio occurs through a nonconserved TRAF3-binding motif.

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2013: Myriam Scherer; Victoria Otto; Nina Reuter; Heinrich Sticht; Nadine Wagenknecht; Thomas Stamminger
Small ubiquitin-related modifier (SUMO) pathway-mediated enhancement of human cytomegalovirus replication correlates with a recruitment of SUMO-1/3 proteins to viral replication compartments.
The Journal of general virology 2013;94(Pt 6):1373-84.
2013: Martin H Griessl; Michael Hensel; Kristin Kassler; Regina Ritter; Tilman E Schäffer; Benedikt Schmid; Heinrich Sticht; York-Dieter Stierhof; Karina U Sturm; Carolin Wagner; Britta Barlag; Christoph Braunsmann; Claudia Danzer; Yves A Muller
Structural Insight into the Giant Ca(2+)-Binding Adhesin SiiE: Implications for the Adhesion of Salmonella enterica to Polarized Epithelial Cells.
Structure (London, England : 1993) 2013;21(5):741-52.
2013: Sarah Jill de Jong; Fabian Giehler; Arnd Kieser; Heinrich Sticht; Jens-Christian Albrecht; Brigitte Biesinger
Noncanonical NF-κB activation by the oncoprotein Tio occurs through a nonconserved TRAF3-binding motif.
Science signaling 2013;6(272):ra27.
2013: Silke Dornieden; Susanne Aileen Funke; Nan Jiang; Carsten Korth; Andreas Müller-Schiffmann; Heinrich Sticht; Yeliz Cinar; Michael Wördehoff; Dieter Willbold
Characterization of a single-chain variable fragment recognizing a linear epitope of aβ: a biotechnical tool for studies on Alzheimer's disease?
PloS one 2013;8(3):e59820.
2013: Kristin Eissmann; Bernhard Fleckenstein; Andrea Gross; Shibo Jiang; Susan Jung; Sebastian Mueller; Heinrich Sticht; Peng Zou; Jutta Eichler; Heide Reil
HIV-1 fusion is blocked through binding of GB Virus C E2D peptides to the HIV-1 gp41 disulfide loop.
PloS one 2013;8(1):e54452.
2013: Angela Seebahn; Heinrich Sticht; Ralf Enz
Expression, purification, and structural analysis of intracellular C-termini from metabotropic glutamate receptors.
Methods in enzymology 2013;520():257-79.
2013: Wei Xiang; Robert Zimmermann; Julia Bussmann; Angela Seebahn; Heinrich Sticht; Volker Weisbach; Cord-Michael Becker
Oxidative stress-induced posttranslational modifications of human hemoglobin in erythrocytes.
Archives of biochemistry and biophysics 2013;529(1):34-44.
2013: Robert Rauh; Daniel Soell; Heinrich Sticht; Alexei Diakov; Silke Haerteis; Bettina Krueger; Viatcheslav Nesterov; Christoph Korbmacher
A mutation in the β-subunit of ENaC identified in a patient with cystic fibrosis-like symptoms has a gain-of-function effect.
American journal of physiology. Lung cellular and molecular physiology 2013;304(1):L43-55.
2012: Pia Rücker; G Matthias Ullmann; Silke A Wieninger; Heinrich Sticht
pH-dependent molecular dynamics of vesicular stomatitis virus glycoprotein G.
Proteins 2012;80(11):2601-13.
2012: Rike Webel; Thomas Wittenberg; Jens Milbradt; Sara M Ø Solbak; Heinrich Sticht; Jutta Eichler; Torgils Fossen; Andrea Groß; Christian Held; Christophe Jardin; Manfred Marschall
Nuclear import of isoforms of the cytomegalovirus kinase pUL97 is mediated by differential activity of NLS1 and NLS2 both acting through classical importin-α binding.
The Journal of general virology 2012;93(Pt 8):1756-68.
2012: Jens Milbradt; Yves A Muller; Madhumati Sevvana; Heinrich Sticht; Sabrina Auerochs; Manfred Marschall
Specific residues of a conserved domain in the N terminus of the human cytomegalovirus pUL50 protein determine its intranuclear interaction with pUL53.
The Journal of biological chemistry 2012;287(28):24004-16.
2012: Olaf G Othersen; Arno G Stefani; Johannes B Huber; Heinrich Sticht
Application of information theory to feature selection in protein docking.
Journal of molecular modeling 2012;18(4):1285-97.
2012: Francesca Pasutto; André Reis; John R Samples; Ursula Schlötzer-Schrehardt; Heinrich Sticht; Nicole Weisschuh; Ted S Acott; Beth Edmunds; Paolo Frezzotti; Eugen Gramer; Kate E Keller; Patricia L Kramer; Christian Y Mardin; Yong-Feng Yang; Matthias Zenkel; Mary K Wirtz
Variants in ASB10 are associated with open-angle glaucoma.
Human molecular genetics 2012;21(6):1336-49.
2012: Andreas Tagariello; Andreas Winterpacht; Y Birkner; C Breuer; Robert Cesnjevar; S Dittrich; J Dotsch; A M Koch; A Ruffer; S Schmidt; H Schneider; Heinrich Sticht; O Toka
Functional null mutations in the gonosomal homologue gene TBL1Y are associated with non-syndromic coarctation of the aorta.
Current molecular medicine 2012;12(2):199-205.
2012: Julia Meier; Heinrich Sticht; Kristin Kassler; Jutta Eichler
Peptides presenting the binding site of human CD4 for the HIV-1 envelope glycoprotein gp120.
Beilstein journal of organic chemistry 2012;8():1858-66.
2012: Silke Haerteis; Felix Brauer; Stefan Brüschke; Robert Rauh; Paul Rösch; Daniel Schaal; Stephan Schwarzinger; Kristian Schweimer; Heinrich Sticht; Christoph Korbmacher
An inhibitory peptide derived from the α-subunit of the epithelial sodium channel (ENaC) shows a helical conformation.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2012;29(5-6):761-74.
2012: Eman Dey Mazumder; Brigitte Scholz; Heinrich Sticht; Benjamin Vogel; Elke Heck; Christophe Jardin; Doris Lengenfelder; Armin Ensser
A molecular model for the differential activation of STAT3 and STAT6 by the herpesviral oncoprotein tip.
PloS one 2012;7(4):e34306.
2011: Christina Schulze; Heinrich Sticht; Petra Meyerhoff; Petra Dietrich
Differential contribution of EF-hands to the Ca²⁺-dependent activation in the plant two-pore channel TPC1.
The Plant journal : for cell and molecular biology 2011;68(3):424-32.
2011: Pia Rücker; Anselm H C Horn; Heike Meiselbach; Heinrich Sticht
A comparative study of HIV-1 and HTLV-I protease structure and dynamics reveals a conserved residue interaction network.
Journal of molecular modeling 2011;17(10):2693-705.
2011: Kathrin Mandery; Ingrid Schmidt; Heinrich Sticht; Bettina Balk; Krystyna Bujok; Christina Fahrmayr; Martin F Fromm; Hartmut Glaeser
Functional and structural relevance of conserved positively charged lysine residues in organic anion transporting polypeptide 1B3.
Molecular pharmacology 2011;80(3):400-6.
2011: Sonja Pötzsch; Pia Rücker; Nadja Spindler; Thomas Stamminger; Heinrich Sticht; Florian Weisel; Anna-Katharina Wiegers; Tina Baroti; Tanja Fisch; Nina Grieb; Michael Mach; Luis Martin-Parras; Thomas H Winkler
B cell repertoire analysis identifies new antigenic domains on glycoprotein B of human cytomegalovirus which are target of neutralizing antibodies.
PLoS pathogens 2011;7(8):e1002172.
2011: Heike Meiselbach; Heinrich Sticht
Effect of the SH3-SH2 domain linker sequence on the structure of Hck kinase.
Journal of molecular modeling 2011;17(8):1927-34.
2011: Andreas Müller-Schiffmann; Aksana Andreyeva; Kurt Gottmann; Anselm H C Horn; Carsten Korth; Heinrich Sticht
Molecular engineering of a secreted, highly homogeneous, and neurotoxic aβ dimer.
ACS chemical neuroscience 2011;2(5):242-8.
2011: Eva Dütting; Nadja Schröder-Kress; Heinrich Sticht; Ralf Enz
SUMO E3 ligases are expressed in the retina and regulate SUMOylation of the metabotropic glutamate receptor 8b.
The Biochemical journal 2011;435(2):365-71.
2011: Katrin Hochdörffer; Julia März-Berberich; Luitgard Nagel-Steger; Matthias Epple; Wolfgang Meyer-Zaika; Anselm H C Horn; Heinrich Sticht; Sharmistha Sinha; Gal Bitan; Thomas Schrader
Rational design of β-sheet ligands against Aβ42-induced toxicity.
Journal of the American Chemical Society 2011;133(12):4348-58.
2011: Rike Webel; Jens Milbradt; Sabrina Auerochs; Vera Schregel; Christian Held; Katharina Nöbauer; Ebrahim Razzazi-Fazeli; Christophe Jardin; Thomas Wittenberg; Heinrich Sticht; Manfred Marschall
Two isoforms of the protein kinase pUL97 of human cytomegalovirus are differentially regulated in their nuclear translocation.
The Journal of general virology 2011;92(Pt 3):638-49.
2011: Angela Seebahn; Holger Dinkel; Jeannine Mohrlüder; Rudolf Hartmann; Nico Vogel; Cord-Michael Becker; Heinrich Sticht; Ralf Enz
Structural characterization of intracellular C-terminal domains of group III metabotropic glutamate receptors.
FEBS letters 2011;585(3):511-6.
2011: Kristin Kassler; Julia Meier; Jutta Eichler; Heinrich Sticht
Structural Basis for Species Selectivity in the HIV-1 gp120-CD4 Interaction: Restoring Affinity to gp120 in Murine CD4 Mimetic Peptides.
Advances in bioinformatics 2011;2011():736593.
2010: Madhumati Sevvana; Kristin Kassler; Josefin Ahnström; Sigrid Weiler; Björn Dahlbäck; Heinrich Sticht; Yves A Muller
Mouse ApoM displays an unprecedented seven-stranded lipocalin fold: folding decoy or alternative native fold?
Journal of molecular biology 2010;404(3):363-71.
2010: Andreas Müller-Schiffmann; Julia März-Berberich; Aksana Andreyeva; Raik Rönicke; Dirk Bartnik; Oleksandr Brener; Janine Kutzsche; Anselm H C Horn; Marco Hellmert; Jolanta Polkowska; Kurt Gottmann; Klaus G Reymann; Susanne Aileen Funke; Luitgart Nagel-Steger; Christine Moriscot; Guy Schoehn; Heinrich Sticht; Dieter Willbold; Thomas Schrader; Carsten Korth
Combining independent drug classes into superior, synergistically acting hybrid molecules.
Angewandte Chemie (International ed. in English) 2010;49(46):8743-6.
2010: Pia Dirauf; Heike Meiselbach; Heinrich Sticht
Effects of the V82A and I54V mutations on the dynamics and ligand binding properties of HIV-1 protease.
Journal of molecular modeling 2010;16(10):1577-83.
2010: Susanne Aileen Funke; Dirk Bartnik; Renu Batra-Safferling; Oleksandr Brener; Anselm H C Horn; Inga Kadish; Carsten Korth; Christine Moriscot; Andreas Müller-Schiffmann; Luitgard Nagel-Steger; Guy Schoehn; Torsten Sehl; Heinrich Sticht; Thomas van Groen; Dieter Willbold
Oral treatment with the d-enantiomeric peptide D3 improves the pathology and behavior of Alzheimer's Disease transgenic mice.
ACS chemical neuroscience 2010;1(9):639-48.
2010: Markus Zweier; Anne Gregor; Christiane Zweier; Hartmut Engels; Heinrich Sticht; Eva Wohlleber; Emilia K Bijlsma; Susan E Holder; Martin Zenker; Eva Rossier; Ute Grasshoff; Diana S Johnson; Lisa Robertson; Helen V Firth; Arif B Ekici; André Reis; Anita Rauch
Mutations in MEF2C from the 5q14.3q15 microdeletion syndrome region are a frequent cause of severe mental retardation and diminish MECP2 and CDKL5 expression.
Human mutation 2010;31(6):722-33.
2010: Cindy Schulenburg; Ulrich Weininger; Piotr Neumann; Heike Meiselbach; Milton T Stubbs; Heinrich Sticht; Jochen Balbach; Renate Ulbrich-Hofmann; Ulrich Arnold
Impact of the C-terminal disulfide bond on the folding and stability of onconase.
Chembiochem : a European journal of chemical biology 2010;11(7):978-86.
2010: Kristin Kassler; Anselm H C Horn; Heinrich Sticht
Effect of pathogenic mutations on the structure and dynamics of Alzheimer's A beta 42-amyloid oligomers.
Journal of molecular modeling 2010;16(5):1011-20.
2010: Jens Milbradt; Rike Webel; Sabrina Auerochs; Heinrich Sticht; Manfred Marschall
Novel mode of phosphorylation-triggered reorganization of the nuclear lamina during nuclear egress of human cytomegalovirus.
The Journal of biological chemistry 2010;285(18):13979-89.
2010: Anselm H C Horn; Heinrich Sticht
Amyloid-beta42 oligomer structures from fibrils: a systematic molecular dynamics study.
The journal of physical chemistry. B 2010;114(6):2219-26.
2009: Francesca Pasutto; Tomoya Matsumoto; Christian Y Mardin; Heinrich Sticht; Johann H Brandstätter; Karin Michels-Rautenstrauss; Nicole Weisschuh; Eugen Gramer; Wishal D Ramdas; Leonieke M E van Koolwijk; Caroline C W Klaver; Johannes R Vingerling; Bernhard H F Weber; Friedrich E Kruse; Bernd Rautenstrauss; Yves-Alain Barde; André Reis
Heterozygous NTF4 mutations impairing neurotrophin-4 signaling in patients with primary open-angle glaucoma.
American journal of human genetics 2009;85(4):447-56.
2009: Alejandro Leal; Kathrin Huehne; Finn Bauer; Heinrich Sticht; Philipp Berger; Ueli Suter; Bernal Morera; Gerardo Del Valle; James R Lupski; Arif B Ekici; Francesca Pasutto; Sabine Endele; Ramiro Barrantes; Corinna Berghoff; Martin Berghoff; Bernhard Neundörfer; Dieter Heuss; Thomas Dorn; Peter Young; Lisa Santolin; Thomas Uhlmann; Michael Meisterernst; Michael Werner Sereda; Michael Sereda; Ruth Martha Stassart; Klaus-Armin Nave; André Reis; Gerd Meyer zu Horste; Bernd Rautenstrauss
Identification of the variant Ala335Val of MED25 as responsible for CMT2B2: molecular data, functional studies of the SH3 recognition motif and correlation between wild-type MED25 and PMP22 RNA levels in CMT1A animal models.
Neurogenetics 2009;10(4):275-87.
2009: Christian Thiel; Martin Wilken; Martin Zenker; Heinrich Sticht; Raimund Fahsold; Gabriele C Gusek-Schneider; Anita Rauch
Independent NF1 and PTPN11 mutations in a family with neurofibromatosis-Noonan syndrome.
American journal of medical genetics. Part A 2009;149A(6):1263-7.
2009: Jens Milbradt; Sabrina Auerochs; Heinrich Sticht; Manfred Marschall
Cytomegaloviral proteins that associate with the nuclear lamina: components of a postulated nuclear egress complex.
The Journal of general virology 2009;90(Pt 3):579-90.
2009: Daniela Muhl; Nadja Jessberger; Kristin Hasselt; Christophe Jardin; Heinrich Sticht; Andreas Burkovski
DNA binding by Corynebacterium glutamicum TetR-type transcription regulator AmtR.
BMC molecular biology 2009;10():73.
2008: Christophe Jardin; Anselm H C Horn; Gudrun Schürer; Heinrich Sticht
Insight into the phosphoryl transfer of the Escherichia coli glucose phosphotransferase system from QM/MM simulations.
The journal of physical chemistry. B 2008;112(42):13391-400.
2008: Gabriela Chavarria-Soley; Heinrich Sticht; Eleni Aklillu; Magnus Ingelman-Sundberg; Francesca Pasutto; André Reis; Bernd Rautenstrauss
Mutations in CYP1B1 cause primary congenital glaucoma by reduction of either activity or abundance of the enzyme.
Human mutation 2008;29(9):1147-53.
2008: Christian T Thiel; Birgit Knebel; Ina Knerr; Heinrich Sticht; Dirk Müller-Wieland; Martin Zenker; André Reis; Helmuth-Günther Dörr; Anita Rauch
Two novel mutations in the insulin binding subunit of the insulin receptor gene without insulin binding impairment in a patient with Rabson-Mendenhall syndrome.
Molecular genetics and metabolism 2008;94(3):356-62.
2008: Melanie Rose; Eva Dütting; Nicolas W J Schröder; Heinrich Sticht; Johann Helmut Brandstätter; Ralf Enz
PNUTS forms a trimeric protein complex with GABA(C) receptors and protein phosphatase 1.
Molecular and cellular neurosciences 2008;37(4):808-19.
2008: Francesca Pasutto; Christian Y Mardin; Karin Michels-Rautenstrauss; Bernhard H F Weber; Heinrich Sticht; Gabriela Chavarria-Soley; Bernd Rautenstrauss; Friedrich E Kruse; André Reis
Profiling of WDR36 missense variants in German patients with glaucoma.
Investigative ophthalmology & visual science 2008;49(1):270-4.
2007: Holger Dinkel; Heinrich Sticht
A computational strategy for the prediction of functional linear peptide motifs in proteins.
Bioinformatics (Oxford, England) 2007;23(24):3297-303.
2007: Nadine Homeyer; Timm Essigke; G Matthias Ullmann; Heinrich Sticht
Effects of histidine protonation and phosphorylation on histidine-containing phosphocarrier protein structure, dynamics, and physicochemical properties.
Biochemistry 2007;46(43):12314-26.
2007: Finn Bauer; Heinrich Sticht
A proline to glycine mutation in the Lck SH3-domain affects conformational sampling and increases ligand binding affinity.
FEBS letters 2007;581(8):1555-60.
2007: Wolfgang Müller; Heinrich Sticht
A protein-specifically adapted scoring function for the reranking of docking solutions.
Proteins 2007;67(1):98-111.
2007: Francesca Pasutto; Heinrich Sticht; Gerhard Hammersen; Gabriele Gillessen-Kaesbach; David R FitzPatrick; Gudrun Nürnberg; Frank Brasch; Heidemarie Schirmer-Zimmermann; John Tolmie; David Chitayat; Gunnar Houge; Lorena Fernández-Martínez; Sarah Keating; Geert Mortier; Raoul Hennekam; Axel von der Wense; Anne Slavotinek; Peter Meinecke; Pierre Bitoun; Christian Becker; Peter Nürnberg; André Reis; Anita Rauch
Mutations in STRA6 cause a broad spectrum of malformations including anophthalmia, congenital heart defects, diaphragmatic hernia, alveolar capillary dysplasia, lung hypoplasia, and mental retardation.
American journal of human genetics 2007;80(3):550-60.
2007: Christiane Zweier; Heinrich Sticht; Inci Aydin-Yaylagül; Christine E Campbell; Anita Rauch
Human TBX1 missense mutations cause gain of function resulting in the same phenotype as 22q11.2 deletions.
American journal of human genetics 2007;80(3):510-7.
2007: Sandra M Mueller; Birgit Schaetz; Kathrin Eismann; Silke Bergmann; Michael Bauerle; Matthias Schmitt-Haendle; Hauke Walter; Barbara Schmidt; Klaus Korn; Heinrich Sticht; Bernd M Spriewald; Ellen G Harrer; Thomas Harrer
Dual selection pressure by drugs and HLA class I-restricted immune responses on human immunodeficiency virus type 1 protease.
Journal of virology 2007;81(6):2887-98.
2007: Nadine Homeyer; Timm Essigke; Heike Meiselbach; G Matthias Ullmann; Heinrich Sticht
Effect of HPr phosphorylation on structure, dynamics, and interactions in the course of transcriptional control.
Journal of molecular modeling 2007;13(3):431-44.
2007: Johannes Romir; Hauke Lilie; Claudia Egerer-Sieber; Finn Bauer; Heinrich Sticht; Yves A Muller
Crystal structure analysis and solution studies of human Lck-SH3; zinc-induced homodimerization competes with the binding of proline-rich motifs.
Journal of molecular biology 2007;365(5):1417-28.
2007: Heike Meiselbach; Anselm H C Horn; Thomas Harrer; Heinrich Sticht
Insights into amprenavir resistance in E35D HIV-1 protease mutation from molecular dynamics and binding free-energy calculations.
Journal of molecular modeling 2007;13(2):297-304.
2006: Daniel Romaker; Vera Schregel; Katja Maurer; Sabrina Auerochs; Andrea Marzi; Heinrich Sticht; Manfred Marschall
Analysis of the structure-activity relationship of four herpesviral UL97 subfamily protein kinases reveals partial but not full functional conservation.
Journal of medicinal chemistry 2006;49(24):7044-53.
2006: Tatiana Cheusova; Muhammad Amir Khan; Steffen Wolfgang Schubert; Anne-Claude Gavin; Thierry Buchou; Germaine Jacob; Heinrich Sticht; Jorge E Allende; Brigitte Boldyreff; Hans Rudolf Brenner; Said Hashemolhosseini
Casein kinase 2-dependent serine phosphorylation of MuSK regulates acetylcholine receptor aggregation at the neuromuscular junction.
Genes & development 2006;20(13):1800-16.
2006: Stephan Schwarzinger; Anselm H C Horn; Jan Ziegler; Heinrich Sticht
Rare large scale subdomain motions in prion protein can initiate aggregation.
Journal of biomolecular structure & dynamics 2006;23(6):581-90.
2006: Martin Zenker; Lutz Nährlich; Heinrich Sticht; André Reis; Denise Horn
Genotype-epigenotype-phenotype correlations in females with frontometaphyseal dysplasia.
American journal of medical genetics. Part A 2006;140(10):1069-73.
2006: Wolfgang Müller; Nicola Horstmann; Wolfgang Hillen; Heinrich Sticht
The transcription regulator RbsR represents a novel interaction partner of the phosphoprotein HPr-Ser46-P in Bacillus subtilis.
The FEBS journal 2006;273(6):1251-61.
2006: Nadine Homeyer; Anselm H C Horn; Harald Lanig; Heinrich Sticht
AMBER force-field parameters for phosphorylated amino acids in different protonation states: phosphoserine, phosphothreonine, phosphotyrosine, and phosphohistidine.
Journal of molecular modeling 2006;12(3):281-9.
2006: Markus Zeeb; Klaas E A Max; Ulrich Weininger; Christian Löw; Heinrich Sticht; Jochen Balbach
Recognition of T-rich single-stranded DNA by the cold shock protein Bs-CspB in solution.
Nucleic acids research 2006;34(16):4561-71.
2006: Heinrich Sticht; Said Hashemolhosseini
A common structural mechanism underlying GCMB mutations that cause hypoparathyroidism.
Medical hypotheses 2006;67(3):482-7.
2006: Heike Meiselbach; Heinrich Sticht; Ralf Enz
Structural analysis of the protein phosphatase 1 docking motif: molecular description of binding specificities identifies interacting proteins.
Chemistry & biology 2006;13(1):49-59.
2005: Christian T Thiel; Denise Horn; Bernhard Zabel; Arif B Ekici; Kelly Salinas; Erich Gebhart; Franz Rüschendorf; Heinrich Sticht; Jürgen Spranger; Dietmar Müller; Christiane Zweier; Mark E Schmitt; André Reis; Anita Rauch
Severely incapacitating mutations in patients with extreme short stature identify RNA-processing endoribonuclease RMRP as an essential cell growth regulator.
American journal of human genetics 2005;77(5):795-806.
2005: Gregor Hofmann; Kristian Schweimer; Anke Kiessling; Edith Hofinger; Finn Bauer; Silke Hoffmann; Paul Rösch; Iain D Campbell; Joern Werner; Heinrich Sticht
Binding, domain orientation, and dynamics of the Lck SH3-SH2 domain pair and comparison with other Src-family kinases.
Biochemistry 2005;44(39):13043-50.
2005: Finn Bauer; Kristian Schweimer; Heike Meiselbach; Silke Hoffmann; Paul Rösch; Heinrich Sticht
Structural characterization of Lyn-SH3 domain in complex with a herpesviral protein reveals an extended recognition motif that enhances binding affinity.
Protein science : a publication of the Protein Society 2005;14(10):2487-98.
2005: Edith Hofinger; Heinrich Sticht
Multiple modes of interaction between Lck and CD28.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(7):3839-40; author reply 3840.
2005: Matthias Lechmann; Nicole Kotzor; Elisabeth Zinser; Alexander T Prechtel; Heinrich Sticht; Alexander Steinkasserer
CD83 is a dimer: Comparative analysis of monomeric and dimeric isoforms.
Biochemical and biophysical research communications 2005;329(1):132-9.
2005: Bianca-Lucia Marg; Kristian Schweimer; Heinrich Sticht; Dieter Oesterhelt
A two-alpha-helix extra domain mediates the halophilic character of a plant-type ferredoxin from halophilic archaea.
Biochemistry 2005;44(1):29-39.
2004: Finn Bauer; Edith Hofinger; Silke Hoffmann; Paul Rösch; Kristian Schweimer; Heinrich Sticht
Characterization of Lck-binding elements in the herpesviral regulatory Tip protein.
Biochemistry 2004;43(47):14932-9.
2004: Simon Hör; Heide Pirzer; Laure Dumoutier; Finn Bauer; Sabine Wittmann; Heinrich Sticht; Jean-Christophe Renauld; Rene de Waal Malefyt; Helmut Fickenscher
The T-cell lymphokine interleukin-26 targets epithelial cells through the interleukin-20 receptor 1 and interleukin-10 receptor 2 chains.
The Journal of biological chemistry 2004;279(32):33343-51.
2004: Dorothee Preimel; Heinrich Sticht
Molecular modeling of the interleukin-19 receptor complex. Novel aspects of receptor recognition in the interleukin-10 cytokine family.
Journal of molecular modeling 2004;10(4):290-6.
2004: Martin Zenker; Anita Rauch; Andreas Winterpacht; Andreas Tagariello; Cornelia Kraus; Thomas Rupprecht; Heinrich Sticht; André Reis
A dual phenotype of periventricular nodular heterotopia and frontometaphyseal dysplasia in one patient caused by a single FLNA mutation leading to two functionally different aberrant transcripts.
American journal of human genetics 2004;74(4):731-7.
2004: Hubert Jäger; Bettina Herzig; Alf Herzig; Heinrich Sticht; Christian F Lehner; Stefan Heidmann
Structure predictions and interaction studies indicate homology of separase N-terminal regulatory domains and Drosophila THR.
Cell cycle (Georgetown, Tex.) 2004;3(2):182-8.
2004: Sylvia Escher; Ulf Forssmann; Adjoa Frimpong-Boateng; Knut Adermann; Jalal Vakili; Heinrich Sticht; Michel detheux
Functional analysis of chemically synthesized derivatives of the human CC chemokine CCL15/HCC-2, a high affinity CCR1 ligand.
The journal of peptide research : official journal of the American Peptide Society 2004;63(1):36-47.
2003: Cristina Croci; Heinrich Sticht; Johann Helmut Brandstätter; Ralf Enz
Group I metabotropic glutamate receptors bind to protein phosphatase 1C. Mapping and modeling of interacting sequences.
The Journal of biological chemistry 2003;278(50):50682-90.
2003: Jan Ziegler; Heinrich Sticht; Ute C Marx; Wolfgang Müller; Paul Rösch; Stephan Schwarzinger
CD and NMR studies of prion protein (PrP) helix 1. Novel implications for its role in the PrPC-->PrPSc conversion process.
The Journal of biological chemistry 2003;278(50):50175-81.
2003: Kristian Schweimer; Anke Kiessling; Finn Bauer; Simon Hör; Silke Hoffmann; Paul Rösch; Heinrich Sticht
Sequence-specific 1H, 13C and 15N resonance assignments of the SH3-SH2 domain pair from the human tyrosine kinase Lck.
Journal of biomolecular NMR 2003;27(4):405-6.
2002: Kristian Schweimer; Silke Hoffmann; Finn Bauer; Ute Friedrich; Christian Kardinal; Stephan M Feller; Brigitte Biesinger; Heinrich Sticht
Structural investigation of the binding of a herpesviral protein to the SH3 domain of tyrosine kinase Lck.
Biochemistry 2002;41(16):5120-30.
2002: Matthias Lechmann; Elisabeth Kremmer; Heinrich Sticht; Alexander Steinkasserer
Overexpression, purification, and biochemical characterization of the extracellular human CD83 domain and generation of monoclonal antibodies.
Protein expression and purification 2002;24(3):445-52.
2002: Helmut Fickenscher; Simon Hör; Heide Küpers; Andrea Knappe; Sabine Wittmann; Heinrich Sticht
The interleukin-10 family of cytokines.
Trends in immunology 2002;23(2):89-96.
2001: Philipp Neudecker; Heinrich Sticht; Paul Rösch
Improving the efficiency of the Gaussian conformational database potential for the refinement of protein and nucleic acid structures.
Journal of biomolecular NMR 2001;21(4):373-5.
2001: Finn Bauer; Kristian Schweimer; Enno Klüver; J R Conejo-Garcia; Wolf-Georg Forssmann; Paul Rösch; Knut Adermann; Heinrich Sticht
Structure determination of human and murine beta-defensins reveals structural conservation in the absence of significant sequence similarity.
Protein science : a publication of the Protein Society 2001;10(12):2470-9.
2001: Cornelius Faber; M Schärpf; T Becker; Heinrich Sticht; Paul Rösch
The structure of the coliphage HK022 Nun protein-lambda-phage boxB RNA complex. Implications for the mechanism of transcription termination.
The Journal of biological chemistry 2001;276(34):32064-70.
2001: Philipp Neudecker; Kristian Schweimer; Jörg Nerkamp; Stephan Scheurer; Stefan Vieths; Heinrich Sticht; Paul Rösch
Allergic cross-reactivity made visible: solution structure of the major cherry allergen Pru av 1.
The Journal of biological chemistry 2001;276(25):22756-63.
2000: J Wastl; Evert C Duin; Lucia Iuzzolino; W Dörner; T Link; Silke Hoffmann; Heinrich Sticht; Holger Dau; Klaus Lingelbach; Uwe-G Maier
Eukaryotically encoded and chloroplast-located rubredoxin is associated with photosystem II.
The Journal of biological chemistry 2000;275(39):30058-63.
2000: Philipp Neudecker; Kristian Schweimer; Jörg Nerkamp; M Boehm; Stephan Scheurer; Stefan Vieths; Heinrich Sticht; Paul Rösch
Sequence-specific 1H, 13C and 15N resonance assignments of the major cherry allergen Pru a 1.
Journal of biomolecular NMR 2000;18(1):71-2.
2000: Kristian Schweimer; Silke Hoffmann; J Wastl; Uwe-G Maier; Paul Rösch; Heinrich Sticht
Solution structure of a zinc substituted eukaryotic rubredoxin from the cryptomonad alga Guillardia theta.
Protein science : a publication of the Protein Society 2000;9(8):1474-86.
2000: Cornelius Faber; Heinrich Sticht; Kristian Schweimer; Paul Rösch
Structural rearrangements of HIV-1 Tat-responsive RNA upon binding of neomycin B.
The Journal of biological chemistry 2000;275(27):20660-6.
2000: J Wastl; Heinrich Sticht; Uwe-G Maier; Paul Rösch; Silke Hoffmann
Identification and characterization of a eukaryotically encoded rubredoxin in a cryptomonad alga.
FEBS letters 2000;471(2-3):191-6.
2000: Kristian Schweimer; B L Marg; D Oesterhelt; Paul Rösch; Heinrich Sticht
Sequence-specific 1H, 13C and 15N resonance assignments and secondary structure of [2Fe-2S] ferredoxin from Halobacterium salinarum.
Journal of biomolecular NMR 2000;16(4):347-8.
2000: M Schärpf; Heinrich Sticht; Kristian Schweimer; M Boehm; S Hoffmann; Paul Rösch
Antitermination in bacteriophage lambda. The structure of the N36 peptide-boxB RNA complex.
European journal of biochemistry / FEBS 2000;267(8):2397-408.
1999: Sylvia Escher; Heinrich Sticht; Wolf-Georg Forssmann; Paul Rösch; Knut Adermann
Synthesis and characterization of the human CC chemokine HCC-2.
The journal of peptide research : official journal of the American Peptide Society 1999;54(6):505-13.
1999: Heinrich Sticht; Sylvia Escher; Kristian Schweimer; Wolf-Georg Forssmann; Paul Rösch; Knut Adermann
Solution structure of the human CC chemokine 2: A monomeric representative of the CC chemokine subtype.
Biochemistry 1999;38(19):5995-6002.
1998: M J Seewald; AU Metzger; Dieter Willbold; Paul Rösch; Heinrich Sticht
Structural model of the HIV-1 Tat(46-58)-TAR complex.
Journal of biomolecular structure & dynamics 1998;16(3):683-92.
1998: Dieter Willbold; AU Metzger; Heinrich Sticht; K C Gallert; R Voit; N Dank; P Bayer; G Krauss; R S Goody; Paul Rösch
Equine infectious anemia virus transactivator is a homeodomain-type protein.
Journal of molecular biology 1998;277(4):749-55.
1998: Heinrich Sticht; Andrew R Pickford; Jennifer R Potts; Iain D Campbell
Solution structure of the glycosylated second type 2 module of fibronectin.
Journal of molecular biology 1998;276(1):177-87.
1998: Heinrich Sticht; Paul Rösch
The structure of iron-sulfur proteins.
Progress in biophysics and molecular biology 1998;70(2):95-136.
1997: Heinrich Sticht; K C Gallert; Gerhard Krauss; Paul Rösch
Homology modeling of adenylosuccinate synthetase from Saccharomyces cerevisiae reveals a possible binding region for single-stranded ARS sequences.
Journal of biomolecular structure & dynamics 1997;14(6):667-75.
1996: B Baumann; Heinrich Sticht; M Schärpf; M Sutter; Wolfgang Haehnel; Paul Rösch
Structure of Synechococcus elongatus [Fe2S2] ferredoxin in solution.
Biochemistry 1996;35(39):12831-41.
1996: Dieter Willbold; A Volkmann; AU Metzger; Heinrich Sticht; R Rosin-Arbesfeld; Arnona Gazit; Abraham Yaniv; R W Frank; Paul Rösch
Structural studies of the equine infectious anemia virus trans-activator protein.
European journal of biochemistry / FEBS 1996;240(1):45-52.
1996: Cornelius Faber; A Lindemann; Heinrich Sticht; Andrzej Ejchart; Andreas J Kungl; M Susani; R W Frank; Dietrich Kraft; M Breitenbach; Paul Rösch
Secondary structure and tertiary fold of the birch pollen allergen Bet v 1 in solution.
The Journal of biological chemistry 1996;271(32):19243-50.
1996: Heinrich Sticht; G Wildegger; D Bentrop; Beatrice Darimont; Reinhard Sterner; Paul Rösch
An NMR-derived model for the solution structure of oxidized Thermotoga maritima 1[Fe4-S4] ferredoxin.
European journal of biochemistry / FEBS 1996;237(3):726-35.
1996: Heinrich Sticht; Manfred Auer; B Schmitt; J Besemer; M Horcher; T Kirsch; Ivan J D Lindley; Paul Rösch
Structure and activity of a chimeric interleukin-8-melanoma-growth-stimulatory-activity protein.
European journal of biochemistry / FEBS 1996;235(1-2):26-35.
1995: Heinrich Sticht; P Bayer; Dieter Willbold; S Dames; C Hilbich; Konrad Beyreuther; R W Frank; Paul Rösch
Structure of amyloid A4-(1-40)-peptide of Alzheimer's disease.
European journal of biochemistry / FEBS 1995;233(1):293-8.
1995: Ute C Marx; S Austermann; P Bayer; Knut Adermann; Andrzej Ejchart; Heinrich Sticht; S Walter; Franz X Schmid; Rainer Jaenicke; Wolf-Georg Forssmann
Structure of human parathyroid hormone 1-37 in solution.
The Journal of biological chemistry 1995;270(25):15194-202.
1994: Heinrich Sticht; Dieter Willbold; Andrzej Ejchart; R Rosin-Arbesfeld; Abraham Yaniv; Arnona Gazit; Paul Rösch
Trifluoroethanol stabilizes a helix-turn-helix motif in equine infectious-anemia-virus trans-activator protein.
European journal of biochemistry / FEBS 1994;225(3):855-61.
1994: Heinrich Sticht; Dieter Willbold; Paul Rösch
Molecular dynamics simulation of equine infectious anemia virus Tat protein in water and in 40% trifluoroethanol.
Journal of biomolecular structure & dynamics 1994;12(1):019-36.
1994: Dieter Willbold; R Rosin-Arbesfeld; Heinrich Sticht; R Frank; Paul Rösch
Structure of the equine infectious anemia virus Tat protein.
Science (New York, N.Y.) 1994;264(5165):1584-7.
1993: Heinrich Sticht; Dieter Willbold; P Bayer; Andrzej Ejchart; F Herrmann; R Rosin-Arbesfeld; Arnona Gazit; Abraham Yaniv; R Frank; Paul Rösch
Equine infectious anemia virus Tat is a predominantly helical protein.
European journal of biochemistry / FEBS 1993;218(3):973-6.