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Ger Stienen

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Josine Marieke de Winter; Alan H Beggs; Danielle Buck; Nigel F Clarke; Carlos Hidalgo; Jeffrey R Jasper; Michael W Lawlor; Fady I Malik; Coen A C Ottenheijm; Ger J M Stienen; Henk Granzier
Troponin activator augments muscle force in nemaline myopathy patients with nebulin mutations.
Theresia Kraft; Judith Montag; Francisco Navarro-Lopez; Ger J M Stienen; Snigdha Tripathi; Nicky M Boontje; Almuth Brandis; Bernhard Brenner; Antonio Francino; Julie L Hodgkinson; E Rosalie Witjas-Paalberends; Jolanda van der Velden
Familial hypertrophic cardiomyopathy: functional effects of myosin mutation R723G in cardiomyocytes.
Saskia Lassche; Henk Granzier; Tom C Irving; George W Padberg; Ger J M Stienen; Silvère M van der Maarel; Baziel G M van Engelen; Nicol C Voermans; Coen A C Ottenheijm
Sarcomeric dysfunction contributes to muscle weakness in facioscapulohumeral muscular dystrophy.

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2013: Josine Marieke de Winter; Alan H Beggs; Danielle Buck; Nigel F Clarke; Carlos Hidalgo; Jeffrey R Jasper; Michael W Lawlor; Fady I Malik; Coen A C Ottenheijm; Ger J M Stienen; Henk Granzier
Troponin activator augments muscle force in nemaline myopathy patients with nebulin mutations.
Journal of medical genetics 2013;50(6):383-92.
2013: Theresia Kraft; Judith Montag; Francisco Navarro-Lopez; Ger J M Stienen; Snigdha Tripathi; Nicky M Boontje; Almuth Brandis; Bernhard Brenner; Antonio Francino; Julie L Hodgkinson; E Rosalie Witjas-Paalberends; Jolanda van der Velden
Familial hypertrophic cardiomyopathy: functional effects of myosin mutation R723G in cardiomyocytes.
Journal of molecular and cellular cardiology 2013;57():13-22.
2013: Saskia Lassche; Henk Granzier; Tom C Irving; George W Padberg; Ger J M Stienen; Silvère M van der Maarel; Baziel G M van Engelen; Nicol C Voermans; Coen A C Ottenheijm
Sarcomeric dysfunction contributes to muscle weakness in facioscapulohumeral muscular dystrophy.
Neurology 2013;80(8):733-7.
2013: Paul J M Wijnker; Cristobal G dos Remedios; Darren Foster; Aisha H Frazier; Anne M Murphy; Ger J M Stienen; Allison L Tsao; Jolanda van der Velden
Impact of site-specific phosphorylation of protein kinase A sites Ser23 and Ser24 of cardiac troponin I in human cardiomyocytes.
American journal of physiology. Heart and circulatory physiology 2013;304(2):H260-8.
2012: Emmy Manders; Frances De Man; Martin Louis Handoko; Ger J M Stienen; Hieronymus W H van Hees; Anton Vonk-Noordegraaf; Nico Westerhof; Coen A C Ottenheijm
Diaphragm weakness in pulmonary arterial hypertension: role of sarcomeric dysfunction.
American journal of physiology. Lung cellular and molecular physiology 2012;303(12):L1070-8.
2012: Loek van Heerebeek; Freek W A Verheugt; Aernout Somsen; Ger J M Stienen; Jolanda van der Velden; Mark P V Begieneman; Jean G F Bronzwaer; Inês Falcão-Pires; Nazha Hamdani; Gerrit J Laarman; Adelino F Leite-Moreira; Hans W M Niessen; Walter J Paulus
Low myocardial protein kinase G activity in heart failure with preserved ejection fraction.
Circulation 2012;126(7):830-9.
2012: Coen A C Ottenheijm; Ger J M Stienen; Baziel G van Engelen; Nicol C Voermans; Bryan D Hudson; Thomas Irving; Henk Granzier
Titin-based stiffening of muscle fibers in Ehlers-Danlos Syndrome.
Journal of applied physiology (Bethesda, Md. : 1985) 2012;112(7):1157-65.
2012: Ger J M Stienen; Coen A C Ottenheijm
Training one type of striated muscle to counteract failure of another type.
The Journal of physiology 2012;590(Pt 6):1307.
2012: Sabine J van Dijk; Marjon van Slegtenhorst; Nicky M Boontje; Lucie Carrier; Dennis Dooijes; Cris dos Remedios; Diederik W D Kuster; Michelle Michels; Aref Najafi; E Rosalie Paalberends; Sakthivel Sadayappan; Ger J M Stienen; Folkert J Ten Cate; Jolanda van der Velden
Contractile dysfunction irrespective of the mutant protein in human hypertrophic cardiomyopathy with normal systolic function.
Circulation. Heart failure 2012;5(1):36-46.
2011: Willem N Welvaart; Christian C Witt; Ra Bouwman; Frances S de Man; Henk Granzier; Stephan A Loer; Hans Niessen; M A Paul; Ger J M Stienen; Hieronymus W H van Hees; Anton Vonk-Noordegraaf; Coen A C Ottenheijm
Selective diaphragm muscle weakness after contractile inactivity during thoracic surgery.
Annals of surgery 2011;254(6):1044-9.
2011: Paul J M Wijnker; Peter Boknik; Cris dos Remedios; Ulrich Gergs; Frank U Müller; Joachim Neumann; Wilhelm Schmitz; Jürgen R Sindermann; Ger J M Stienen; Jolanda van der Velden; Uwe Kirchhefer
Protein phosphatase 2A affects myofilament contractility in non-failing but not in failing human myocardium.
Journal of muscle research and cell motility 2011;32(3):221-33.
2011: Inês Falcão-Pires; Cristina Gavina; Nazha Hamdani; Adelino F Leite-Moreira; Hans W M Niessen; Casper G Schalkwijk; Ger J M Stienen; Jolanda van der Velden; Loek van Heerebeek; Attila Borbély; Walter J Paulus
Diabetes mellitus worsens diastolic left ventricular dysfunction in aortic stenosis through altered myocardial structure and cardiomyocyte stiffness.
Circulation 2011;124(10):1151-9.
2011: Coen A C Ottenheijm; Michael W Lawlor; Ger J M Stienen; Henk Granzier; Alan H Beggs
Changes in cross-bridge cycling underlie muscle weakness in patients with tropomyosin 3-based myopathy.
Human molecular genetics 2011;20(10):2015-25.
2011: Frances De Man; Hieronymus W H van Hees; Martin Louis Handoko; Hans W Niessen; Ingrid Schalij; Marc Humbert; Peter Dorfmüller; Olaf Mercier; Harm J Bogaard; Piet E Postmus; Nico Westerhof; Ger J M Stienen; Willem J van der Laarse; Anton Vonk-Noordegraaf; Coen A C Ottenheijm
Diaphragm muscle fiber weakness in pulmonary hypertension.
American journal of respiratory and critical care medicine 2011;183(10):1411-8.
2011: Wessel P Brouwer; Sabine J van Dijk; Ger J M Stienen; Albert C van Rossum; Jolanda van der Velden; Tjeerd Germans
The development of familial hypertrophic cardiomyopathy: from mutation to bedside.
European journal of clinical investigation 2011;41(5):568-78.
2011: Nicky M Boontje; Dirk Duncker; Ruud Zaremba; Amanda M G Versteilen; Monique C de Waard; Giulia Mearini; Vincent J de Beer; Lucie Carrier; Lori A Walker; Hans W M Niessen; Dobromir Dobrev; Ger J M Stienen; Dirk J Duncker; Jolanda van der Velden
Enhanced myofilament responsiveness upon β-adrenergic stimulation in post-infarct remodeled myocardium.
Journal of molecular and cellular cardiology 2011;50(3):487-99.
2011: Jolanda van der Velden; Nicky M Boontje; Vincent de Beer; Nazha Hamdani; Wolfgang A Linke; Dirk Duncker; Ger J M Stienen; Dirk J Duncker
Transmural heterogeneity of myofilament function and sarcomeric protein phosphorylation in remodeled myocardium of pigs with a recent myocardial infarction.
Frontiers in physiology 2011;2():83.
2010: Nazha Hamdani; Attila Borbély; Sophie P G R Veenstra; Viola Kooij; Wim Vrydag; Ruud Zaremba; Cris Dos Remedios; Hans W M Niessen; Martin C Michel; Walter J Paulus; Ger J M Stienen; Dirk Duncker
More severe cellular phenotype in human idiopathic dilated cardiomyopathy compared to ischemic heart disease.
Journal of muscle research and cell motility 2010;31(4):289-301.
2010: R Arthur Bouwman; M Jumoke A Vreden; Nazha Hamdani; Lisan E J Wassenaar; Lonneke Smeding; Stephan A Loer; Ger J M Stienen; Regis Lamberts
Effect of bupivacaine on sevoflurane-induced preconditioning in isolated rat hearts.
European journal of pharmacology 2010;647(1-3):132-8.
2010: Viola Kooij; Martina Saes; Kornelia Jaquet; Ruud Zaremba; Darren Foster; Anne M Murphy; Cris Dos Remedios; Jolanda van der Velden; Ger J M Stienen
Effect of troponin I Ser23/24 phosphorylation on Ca2+-sensitivity in human myocardium depends on the phosphorylation background.
Journal of molecular and cellular cardiology 2010;48(5):954-63.
2010: Viola Kooij; Nicky Boontje; Ruud Zaremba; Kornelia Jaquet; Cris dos Remedios; Ger J M Stienen; Jolanda van der Velden
Protein kinase C alpha and epsilon phosphorylation of troponin and myosin binding protein C reduce Ca2+ sensitivity in human myocardium.
Basic research in cardiology 2010;105(2):289-300.
2009: Sabine J van Dijk; Rozemarije A Holewijn; Anouk Tebeest; Cris Dos Remedios; Ger J M Stienen; Jolanda van der Velden
A piece of the human heart: variance of protein phosphorylation in left ventricular samples from end-stage primary cardiomyopathy patients.
Journal of muscle research and cell motility 2009;30(7-8):299-302.
2009: Regis Lamberts; Geert Onderwater; Nazha Hamdani; M Jumoke A Vreden; Jeroen Steenhuisen; Etto C Eringa; Stephan A Loer; Ger J M Stienen; R Arthur Bouwman
Reactive oxygen species-induced stimulation of 5'AMP-activated protein kinase mediates sevoflurane-induced cardioprotection.
Circulation 2009;120(11 Suppl):S10-5.
2009: Nazha Hamdani; Walter J Paulus; Loek van Heerebeek; Attila Borbély; Nicky M Boontje; Marian J Zuidwijk; Jean G F Bronzwaer; Warner S Simonides; Hans W M Niessen; Ger J M Stienen; Dirk Duncker
Distinct myocardial effects of beta-blocker therapy in heart failure with normal and reduced left ventricular ejection fraction.
European heart journal 2009;30(15):1863-72.
2009: Dirk J Duncker; Nicky M Boontje; Dirk Duncker; Amanda Versteilen; Judith Krysiak; Giulia Mearini; Ali El-Armouche; Vincent de Beer; Jos M J Lamers; Lucie Carrier; Lori A Walker; Wolfgang A Linke; Ger J M Stienen; Jolanda van der Velden
Prevention of myofilament dysfunction by beta-blocker therapy in postinfarct remodeling.
Circulation. Heart failure 2009;2(3):233-42.
2009: Attila Borbély; Ines Falcao-Pires; Loek van Heerebeek; Nazha Hamdani; István Ferenc Édes; Cristina Gavina; Adelino F Leite-Moreira; Jean G F Bronzwaer; Zoltán Papp; Jolanda van der Velden; Ger J M Stienen; Walter J Paulus
Hypophosphorylation of the Stiff N2B titin isoform raises cardiomyocyte resting tension in failing human myocardium.
Circulation research 2009;104(6):780-6.
2009: Sabine J van Dijk; Dennis Dooijes; Cris dos Remedios; Michelle Michels; Jos M J Lamers; Saul Winegrad; Saskia Schlossarek; Lucie Carrier; Folkert J Ten Cate; Ger J M Stienen; Jolanda van der Velden
Cardiac myosin-binding protein C mutations and hypertrophic cardiomyopathy: haploinsufficiency, deranged phosphorylation, and cardiomyocyte dysfunction.
Circulation 2009;119(11):1473-83.
2008: Stephanie Reis; Christoph Littwitz; Sebastian Preilowski; Andreas Mügge; Ger J M Stienen; Lutz Pott; Kornelia Jaquet
Expression of cTnI-R145G affects shortening properties of adult rat cardiomyocytes.
Pflügers Archiv : European journal of physiology 2008;457(1):17-24.
2008: Zita Hertelendi; Attila Tóth; Attila Borbély; Zoltán Galajda; Jolanda van der Velden; Ger J M Stienen; István Ferenc Édes; Zoltán Papp
Oxidation of myofilament protein sulfhydryl groups reduces the contractile force and its Ca2+ sensitivity in human cardiomyocytes.
Antioxidants & redox signaling 2008;10(7):1175-84.
2008: Cristina Chimenti; Nazha Hamdani; Nicky M Boontje; Francesco DeCobelli; Antonio Esposito; Jean G F Bronzwaer; Ger J M Stienen; Matteo A Russo; Walter J Paulus; Andrea Frustaci; Jolanda van der Velden
Myofilament degradation and dysfunction of human cardiomyocytes in Fabry disease.
The American journal of pathology 2008;172(6):1482-90.
2008: Nazha Hamdani; Viola Kooij; Sabine van Dijk; Daphne Merkus; Walter J Paulus; Cris Dos Remedios; Dirk J Duncker; Ger J M Stienen; Dirk Duncker
Sarcomeric dysfunction in heart failure.
Cardiovascular research 2008;77(4):649-58.
2008: Sabine J van Dijk; Nazha Hamdani; Ger J M Stienen; Jolanda van der Velden
Myocardial adaptations in the failing heart: cause or consequence?
Journal of muscle research and cell motility 2008;29(6-8):159-62.
2008: Nazha Hamdani; Monique de Waard; Andrew E Messer; Nicky M Boontje; Viola Kooij; Sabine van Dijk; Amanda Versteilen; Regis Lamberts; Daphne Merkus; Cris Dos Remedios; Dirk J Duncker; Attila Borbely; Zoltan Papp; Walter Paulus; Ger J M Stienen; Steven B Marston; Dirk Duncker
Myofilament dysfunction in cardiac disease from mice to men.
Journal of muscle research and cell motility 2008;29(6-8):189-201.
2008: Loek van Heerebeek; Nazha Hamdani; Martin Louis Handoko; Ines Falcao-Pires; René J P Musters; Koba Kupreishvili; Alexander J J IJsselmuiden; Casper G Schalkwijk; Jean G F Bronzwaer; Michaela Diamant; Attila Borbély; Jolanda van der Velden; Ger J M Stienen; Gert-Jan Laarman; Hans W M Niessen; Walter J Paulus
Diastolic stiffness of the failing diabetic heart: importance of fibrosis, advanced glycation end products, and myocyte resting tension.
Circulation 2008;117(1):43-51.
2007: S Cora Verduyn; Ruud Zaremba; Jolanda van der Velden; Ger J M Stienen
Effects of contractile protein phosphorylation on force development in permeabilized rat cardiac myocytes.
Basic research in cardiology 2007;102(6):476-87.
2007: Pieter P de Tombe; Ger J M Stienen
Impact of temperature on cross-bridge cycling kinetics in rat myocardium.
The Journal of physiology 2007;584(Pt 2):591-600.
2007: Ruud Zaremba; Dirk Duncker; Nazha Hamdani; Jos M J Lamers; Walter J Paulus; Cris Dos Remedios; Dirk J Duncker; Ger J M Stienen; Jolanda van der Velden
Quantitative analysis of myofilament protein phosphorylation in small cardiac biopsies.
Proteomics. Clinical applications 2007;1(10):1285-90.
2007: Regis Lamberts; Eric Caldenhoven; Mirian Lansink; Gerrit Witte; Rob J Vaessen; John St Cyr; Ger J M Stienen
Preservation of diastolic function in monocrotaline-induced right ventricular hypertrophy in rats.
American journal of physiology. Heart and circulatory physiology 2007;293(3):H1869-76.
2007: Regis Lamberts; Nazha Hamdani; Tenoedj W Soekhoe; Nicky M Boontje; Ruud Zaremba; Lori A Walker; Pieter P de Tombe; Jolanda van der Velden; Ger J M Stienen
Frequency-dependent myofilament Ca2+ desensitization in failing rat myocardium.
The Journal of physiology 2007;582(Pt 2):695-709.
2007: István Ferenc Edes; Dániel Czuriga; Gábor Csányi; Stefan Chlopicki; Fabio A Recchia; Attila Borbély; Zoltán Galajda; István Ferenc Édes; Jolanda van der Velden; Ger J M Stienen; Zoltán Papp
Rate of tension redevelopment is not modulated by sarcomere length in permeabilized human, murine, and porcine cardiomyocytes.
American journal of physiology. Regulatory, integrative and comparative physiology 2007;293(1):R20-9.
2007: Monique C de Waard; Dirk Duncker; Virginie Bito; Semir Ozdemir; Liesbeth Biesmans; Nicky M Boontje; Dick H W Dekkers; Kees Schoonderwoerd; Hans C H Schuurbiers; Rini de Crom; Ger J M Stienen; Karin R Sipido; Jos M J Lamers; Dirk J Duncker
Early exercise training normalizes myofilament function and attenuates left ventricular pump dysfunction in mice with a large myocardial infarction.
Circulation research 2007;100(7):1079-88.
2007: Virginie Bito; Jolanda van der Velden; Piet Claus; Christoph Dommke; Alfons Van Lommel; Luc Mortelmans; Erik Verbeken; Bart Bijnens; Ger J M Stienen; Karin R Sipido
Reduced force generating capacity in myocytes from chronically ischemic, hibernating myocardium.
Circulation research 2007;100(2):229-37.
2007: Regis Lamberts; Rob J Vaessen; Nico Westerhof; Ger J M Stienen
Right ventricular hypertrophy causes impairment of left ventricular diastolic function in the rat.
Basic research in cardiology 2007;102(1):19-27.
2006: Nadiya A Narolska; Nicoletta Piroddi; Alexandra Belus; Nicky M Boontje; Beatrice Scellini; Sascha Deppermann; Ruud Zaremba; René J P Musters; Cris dos Remedios; Kornelia Jaquet; Darren Foster; Anne M Murphy; Jennifer E Van Eyk; Chiara Tesi; Corrado Poggesi; Jolanda van der Velden; Ger J M Stienen
Impaired diastolic function after exchange of endogenous troponin I with C-terminal truncated troponin I in human cardiac muscle.
Circulation research 2006;99(9):1012-20.
2006: S Eiras; Nadiya A Narolska; RB van Loon; Nicky M Boontje; Ruud Zaremba; Connie R Jimenez; Frans C Visser; Wim Stooker; Jolanda van der Velden; Ger J M Stienen
Alterations in contractile protein composition and function in human atrial dilatation and atrial fibrillation.
Journal of molecular and cellular cardiology 2006;41(3):467-77.
2006: Loek van Heerebeek; Attila Borbély; Hans W M Niessen; Jean G F Bronzwaer; Jolanda van der Velden; Ger J M Stienen; Wolfgang A Linke; Gert-Jan Laarman; Walter J Paulus
Myocardial structure and function differ in systolic and diastolic heart failure.
Circulation 2006;113(16):1966-73.
2006: Nicoletta Piroddi; Alexandra Belus; S Eiras; Chiara Tesi; Jolanda van der Velden; Corrado Poggesi; Ger J M Stienen
No direct effect of creatine phosphate on the cross-bridge cycle in cardiac myofibrils.
Pflügers Archiv : European journal of physiology 2006;452(1):3-6.
2006: Karen C Vermeulen; Gijs J L Wuite; Ger J M Stienen; Christoph F Schmidt
Optical trap stiffness in the presence and absence of spherical aberrations.
Applied optics 2006;45(8):1812-9.
2006: Jolanda van der Velden; Nadiya A Narolska; Regis Lamberts; Nicky M Boontje; Attila Borbély; Ruud Zaremba; Jean G F Bronzwaer; Zoltán Papp; Kornelia Jaquet; Walter J Paulus; Ger J M Stienen
Functional effects of protein kinase C-mediated myofilament phosphorylation in human myocardium.
Cardiovascular research 2006;69(4):876-87.
2005: Péter Szentesi; Martijn A Bekedam; Brechje J van Beek-Harmsen; Willem J van der Laarse; Ruud Zaremba; a boonstra; Frans C Visser; Ger J M Stienen
Depression of force production and ATPase activity in different types of human skeletal muscle fibers from patients with chronic heart failure.
Journal of applied physiology (Bethesda, Md. : 1985) 2005;99(6):2189-95.
2005: Attila Borbély; Attila Tóth; István Ferenc Édes; Laszlo Virag; Julius Gy Papp; András Varró; Walter J Paulus; Jolanda van der Velden; Ger J M Stienen; Zoltán Papp
Peroxynitrite-induced alpha-actinin nitration and contractile alterations in isolated human myocardial cells.
Cardiovascular research 2005;67(2):225-33.
2005: Attila Borbély; Jolanda van der Velden; Zoltán Papp; Jean G F Bronzwaer; István Ferenc Édes; Ger J M Stienen; Walter J Paulus
Cardiomyocyte stiffness in diastolic heart failure.
Circulation 2005;111(6):774-81.
2005: Nadiya A Narolska; S Eiras; RB van Loon; Nicky M Boontje; Ruud Zaremba; S R Spiegelen Berg; Wim Stooker; M A J M Huybregts; Frans C Visser; Jolanda van der Velden; Ger J M Stienen
Myosin heavy chain composition and the economy of contraction in healthy and diseased human myocardium.
Journal of muscle research and cell motility 2005;26(1):39-48.
2005: Nadiya A Narolska; RB van Loon; Nicky M Boontje; Ruud Zaremba; S Eiras Penas; J Russell; Stefan R Spiegelenberg; M A J M Huybregts; Frans C Visser; JW de Jong; Jolanda van der Velden; Ger J M Stienen
Myocardial contraction is 5-fold more economical in ventricular than in atrial human tissue.
Cardiovascular research 2005;65(1):221-9.
2004: Dirk Duncker; Daphne Merkus; B R Klarenbeek; A T James; Nicky M Boontje; Dick H W Dekkers; Ger J M Stienen; Jos M J Lamers; Dirk J Duncker
Alterations in myofilament function contribute to left ventricular dysfunction in pigs early after myocardial infarction.
Circulation research 2004;95(11):e85-95.
2004: Virginie Bito; Frank R Heinzel; Frank Weidemann; Christoph Dommke; Jolanda van der Velden; Erik Verbeken; Piet Claus; Bart Bijnens; Ivan De Scheerder; Ger J M Stienen; George R Sutherland; Karin R Sipido
Cellular mechanisms of contractile dysfunction in hibernating myocardium.
Circulation research 2004;94(6):794-801.
2004: Zoltán Papp; Jolanda van der Velden; Attila Borbély; István Ferenc Édes; Ger J M Stienen
Effects of Ca2+ -sensitizers in permeabilized cardiac myocytes from donor and end-stage failing human hearts.
Journal of muscle research and cell motility 2004;25(3):219-24.
2003: Wouter de Ruijter; René J P Musters; Christa Boer; Ger J M Stienen; Warner S Simonides; Jaap J de Lange
The cardioprotective effect of sevoflurane depends on protein kinase C activation, opening of mitochondrial K(+)(ATP) channels, and the production of reactive oxygen species.
Anesthesia and analgesia 2003;97(5):1370-6.
2003: Jolanda van der Velden; Zoltán Papp; Nicky M Boontje; Ruud Zaremba; JW de Jong; Paul Janssen; G Hasenfuss; Ger J M Stienen
The effect of myosin light chain 2 dephosphorylation on Ca2+ -sensitivity of force is enhanced in failing human hearts.
Cardiovascular research 2003;57(2):505-14.
2003: Jolanda van der Velden; Zoltán Papp; Nicky M Boontje; Ruud Zaremba; JW de Jong; Paul Janssen; G Hasenfuss; Ger J M Stienen
Myosin light chain composition in non-failing donor and end-stage failing human ventricular myocardium.
Advances in experimental medicine and biology 2003;538():3-15.
2003: Jolanda van der Velden; Zoltán Papp; Ruud Zaremba; Nicky M Boontje; JW de Jong; VJ Owen; P B J Burton; P Goldmann; Kornelia Jaquet; Ger J M Stienen
Increased Ca2+-sensitivity of the contractile apparatus in end-stage human heart failure results from altered phosphorylation of contractile proteins.
Cardiovascular research 2003;57(1):37-47.
2002: Wouter de Ruijter; Ger J M Stienen; Jan van Klarenbosch; Jaap J de Lange
Negative and positive inotropic effects of propofol via L-type calcium channels and the sodium-calcium exchanger in rat cardiac trabeculae.
Anesthesiology 2002;97(5):1146-55.
2002: Zoltán Papp; Agnes Szabó; Jan Paul Barends; Ger J M Stienen
The mechanism of the force enhancement by MgADP under simulated ischaemic conditions in rat cardiac myocytes.
The Journal of physiology 2002;543(Pt 1):177-89.
2002: Jolanda van der Velden; Nicky M Boontje; Zoltán Papp; Lucas J Klein; Frans C Visser; JW de Jong; VJ Owen; P B J Burton; Ger J M Stienen
Calcium sensitivity of force in human ventricular cardiomyocytes from donor and failing hearts.
Basic research in cardiology 2002;97 Suppl 1():I118-26.
2002: I J M Korstjens; C H F C Rouws; Willem J van der Laarse; L Van der Zee; Ger J M Stienen
Myocardial force development and structural changes associated with monocrotaline induced cardiac hypertrophy and heart failure.
Journal of muscle research and cell motility 2002;23(1):93-102.
2002: Karen C Vermeulen; Ger J M Stienen; Christoph F Schmid
Cooperative behavior of molecular motors.
Journal of muscle research and cell motility 2002;23(1):71-9.
2001: J P Ebus; Zoltán Papp; Ruud Zaremba; Ger J M Stienen
Effects of MgATP on ATP utilization and force under normal and simulated ischaemic conditions in rat cardiac trabeculae.
Pflügers Archiv : European journal of physiology 2001;443(1):102-11.
2001: Jolanda van der Velden; Lucas J Klein; Ruud Zaremba; Nicky M Boontje; M A J M Huybregts; Wim Stooker; León Eijsman; JW de Jong; Cees A Visser; Frans C Visser; Ger J M Stienen
Effects of calcium, inorganic phosphate, and pH on isometric force in single skinned cardiomyocytes from donor and failing human hearts.
Circulation 2001;104(10):1140-6.
2001: Péter Szentesi; Ruud Zaremba; W van Mechelen; Ger J M Stienen
ATP utilization for calcium uptake and force production in different types of human skeletal muscle fibres.
The Journal of physiology 2001;531(Pt 2):393-403.
2001: Jan van Klarenbosch; Ger J M Stienen; Wouter de Ruijter; Gert Jan Scheffer; Jaap J de Lange
The differential effect of propofol on contractility of isolated myocardial trabeculae of rat and guinea-pig.
British journal of pharmacology 2001;132(3):742-8.
2001: Fabio Abbate; Jolanda van der Velden; Ger J M Stienen; Arnold De Haan
Post-tetanic potentiation increases energy cost to a higher extent than work in rat fast skeletal muscle.
Journal of muscle research and cell motility 2001;22(8):703-10.
2000: Ger J M Stienen
Chronicle of skinned muscle fibres.
The Journal of physiology 2000;527 Pt 1():1.
2000: Jolanda van der Velden; JW de Jong; VJ Owen; P B J Burton; Ger J M Stienen
Effect of protein kinase A on calcium sensitivity of force and its sarcomere length dependence in human cardiomyocytes.
Cardiovascular research 2000;46(3):487-95.
2000: Zoltán Papp; J van der Velden; Ger J M Stienen
Calpain-I induced alterations in the cytoskeletal structure and impaired mechanical properties of single myocytes of rat heart.
Cardiovascular research 2000;45(4):981-93.
1999: Ger J M Stienen; Zoltán Papp; Ruud Zaremba
Influence of inorganic phosphate and pH on sarcoplasmic reticular ATPase in skinned muscle fibres of Xenopus laevis.
The Journal of physiology 1999;518 ( Pt 3)():735-44.
1999: Jolanda van der Velden; Lucas J Klein; MW van der Bijl; M A J M Huybregts; Wim Stooker; J Witkop; León Eijsman; Cees A Visser; Frans C Visser; Ger J M Stienen
Isometric tension development and its calcium sensitivity in skinned myocyte-sized preparations from different regions of the human heart.
Cardiovascular research 1999;42(3):706-19.
1999: Jolanda van der Velden; Piet Borgdorff; Ger J M Stienen
Minoxidil-induced cardiac hypertrophy in guinea pigs.
Cellular and molecular life sciences : CMLS 1999;55(5):788-98.
1998: Z He; Ger J M Stienen; J P Barends; Michael A Ferenczi
Rate of phosphate release after photoliberation of adenosine 5'-triphosphate in slow and fast skeletal muscle fibers.
Biophysical journal 1998;75(5):2389-401.
1998: Péter Szentesi; Ruud Zaremba; Ger J M Stienen
Calcium handling by the sarcoplasmic reticulum during oscillatory contractions of skinned skeletal muscle fibres.
Journal of muscle research and cell motility 1998;19(6):675-87.
1998: Jolanda van der Velden; Lucas J Klein; MW van der Bijl; M A J M Huybregts; Wim Stooker; J Witkop; León Eijsman; Cees A Visser; Frans C Visser; Ger J M Stienen
Force production in mechanically isolated cardiac myocytes from human ventricular muscle tissue.
Cardiovascular research 1998;38(2):414-23.
1998: Jolanda van der Velden; A F Moorman; Ger J M Stienen
Age-dependent changes in myosin composition correlate with enhanced economy of contraction in guinea-pig hearts.
The Journal of physiology 1998;507 ( Pt 2)():497-510.
1997: Carlo Reggiani; E J Potma; Roberto Bottinelli; Monica Canepari; Maria Antonietta Pellegrino; Ger J M Stienen
Chemo-mechanical energy transduction in relation to myosin isoform composition in skeletal muscle fibres of the rat.
The Journal of physiology 1997;502 ( Pt 2)():449-60.
1997: HP Buschman; Willem J van der Laarse; Ger J M Stienen; G Elzinga
Force and myosin content variation in isolated intact single muscle fibres from Rana temporaria.
Pflügers Archiv : European journal of physiology 1997;434(3):332-4.
1997: HP Buschman; Willem J van der Laarse; Ger J M Stienen; G Elzinga
Variation in normalized isometric tetanic force of isolated fast-twitch muscle fibres of Rana temporaria.
The Journal of experimental biology 1997;200(Pt 3):523-9.
1996: D S Loiselle; Ger J M Stienen; Cornelis Van Hardeveld; E T van der Meulen; G I Zahalak; J Daut; G Elzinga
The effect of hyperosmolality on the rate of heat production of quiescent trabeculae isolated from the rat heart.
The Journal of general physiology 1996;108(6):497-514.
1996: H P Buschman; Willem J van der Laarse; Ger J M Stienen; G Elzinga
Force-dependent and force-independent heat production in single slow- and fast-twitch muscle fibres from Xenopus laevis.
The Journal of physiology 1996;496 ( Pt 2)():503-19.
1996: E J Potma; Ger J M Stienen
Increase in ATP consumption during shortening in skinned fibres from rabbit psoas muscle: effects of inorganic phosphate.
The Journal of physiology 1996;496 ( Pt 1)():1-12.
1996: J P Ebus; Ger J M Stienen
Effects of 2,3-butanedione monoxime on cross-bridge kinetics in rat cardiac muscle.
Pflügers Archiv : European journal of physiology 1996;432(5):921-9.
1996: J P Ebus; Ger J M Stienen
ATPase activity and force production in skinned rat cardiac muscle under isometric and dynamic conditions.
Journal of molecular and cellular cardiology 1996;28(8):1747-57.
1996: Ger J M Stienen; J L Kiers; Roberto Bottinelli; Carlo Reggiani
Myofibrillar ATPase activity in skinned human skeletal muscle fibres: fibre type and temperature dependence.
The Journal of physiology 1996;493 ( Pt 2)():299-307.
1996: J P Ebus; Ger J M Stienen
Origin of concurrent ATPase activities in skinned cardiac trabeculae from rat.
The Journal of physiology 1996;492 ( Pt 3)():675-87.
1995: E J Potma; I A van Graas; Ger J M Stienen
Influence of inorganic phosphate and pH on ATP utilization in fast and slow skeletal muscle fibers.
Biophysical journal 1995;69(6):2580-9.
1995: Ger J M Stienen; Ruud Zaremba; G Elzinga
ATP utilization for calcium uptake and force production in skinned muscle fibres of Xenopus laevis.
The Journal of physiology 1995;482 ( Pt 1)():109-22.
1994: Roberto Bottinelli; Monica Canepari; Carlo Reggiani; Ger J M Stienen
Myofibrillar ATPase activity during isometric contraction and isomyosin composition in rat single skinned muscle fibres.
The Journal of physiology 1994;481 ( Pt 3)():663-75.
1994: E J Potma; I A van Graas; Ger J M Stienen
Effects of pH on myofibrillar ATPase activity in fast and slow skeletal muscle fibers of the rabbit.
Biophysical journal 1994;67(6):2404-10.
1994: J P Ebus; Ger J M Stienen; G Elzinga
Influence of phosphate and pH on myofibrillar ATPase activity and force in skinned cardiac trabeculae from rat.
The Journal of physiology 1994;476(3):501-16.
1994: J C Kentish; Ger J M Stienen
Differential effects of length on maximum force production and myofibrillar ATPase activity in rat skinned cardiac muscle.
The Journal of physiology 1994;475(1):175-84.
1994: E J Potma; Ger J M Stienen; J P Barends; G Elzinga
Myofibrillar ATPase activity and mechanical performance of skinned fibres from rabbit psoas muscle.
The Journal of physiology 1994;474(2):303-17.
1993: Ger J M Stienen; Z Papp; G Elzinga
Calcium modulates the influence of length changes on the myofibrillar adenosine triphosphatase activity in rat skinned cardiac trabeculae.
Pflügers Archiv : European journal of physiology 1993;425(3-4):199-207.
1993: Ger J M Stienen; I A van Graas; G Elzinga
Uptake and caffeine-induced release of calcium in fast muscle fibers of Xenopus laevis: effects of MgATP and P(i).
The American journal of physiology 1993;265(3 Pt 1):C650-7.
1993: D L Dietrich; G R van Leeuwen; Ger J M Stienen; G Elzinga
Stunning does not change the relation between calcium and force in skinned rat trabeculae.
Journal of molecular and cellular cardiology 1993;25(5):541-9.
1993: Jan Lännergren; G Elzinga; Ger J M Stienen
Force relaxation, labile heat and parvalbumin content of skeletal muscle fibres of Xenopus laevis.
The Journal of physiology 1993;463():123-40.
1992: Ger J M Stienen; P G Versteeg; Z Papp; G Elzinga
Mechanical properties of skinned rabbit psoas and soleus muscle fibres during lengthening: effects of phosphate and Ca2+.
The Journal of physiology 1992;451():503-23.
1991: Ger J M Stienen; Michael A Ferenczi
Relaxation from rigor by photolysis of caged-ATP in different types of muscle fibres from Xenopus laevis.
Journal of muscle research and cell motility 1991;12(6):507-16.
1990: Ger J M Stienen; M C Roosemalen; M G Wilson; G Elzinga
Depression of force by phosphate in skinned skeletal muscle fibers of the frog.
The American journal of physiology 1990;259(2 Pt 1):C349-57.
1989: G Elzinga; Ger J M Stienen; M G Wilson
Isometric force production before and after chemical skinning in isolated muscle fibres of the frog Rana temporaria.
The Journal of physiology 1989;410():171-85.
1988: Ger J M Stienen; Willem J van der Laarse; G Elzinga
Dependency of the force-velocity relationships on Mg ATP in different types of muscle fibers from Xenopus laevis.
Biophysical journal 1988;53(6):849-55.
1987: G Elzinga; Jan Lännergren; Ger J M Stienen
Stable maintenance heat rate and contractile properties of different single muscle fibres from Xenopus laevis at 20 degrees C.
The Journal of physiology 1987;393():399-412.
1987: Ger J M Stienen; Willem J van der Laarse; P C Diegenbach; G Elzinga
Relation between force and calcium ion concentration in different fibre types of the iliofibularis muscle of Xenopus laevis.
Pflügers Archiv : European journal of physiology 1987;408(1):63-7.
1987: Ger J M Stienen; Jan Lännergren; G Elzinga
ATPase activity of intact single muscle fibres of Xenopus laevis is related to the rate of force redevelopment after rapid shortening.
Basic research in cardiology 1987;82 Suppl 2():111-7.