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Charles Stiles

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Andrew S Chi; William T Curry; Dora Dias-Santagata; Leif Ellisen; Keith L Ligon; David N Louis; Charles D Stiles; Daphne L Wang; Patrick Y Wen; Tracy T Batchelor; Darrell Borger; A John Iafrate
Prospective, high-throughput molecular profiling of human gliomas.
Jing Zhou; Charles D Stiles
Asleep at the switch: MEK kinases control transit to gliogenesis in developing cortex.
Yongji Tian; Natalie Vena; Jennifer A Chan; Justin M Craig; Levi A Garraway; Stewart Goldman; Mark W Kieran; Azra H Ligon; Neal I Lindeman; Janina A Longtine; Laura E MacConaill; Madeha Mahmoud; Memet Ozek; Veena Rajaram; Benjamin E Rich; Sandro Santagata; AYDIN SAV; Charles D Stiles; Hala Taha; Keith L Ligon
Detection of KIAA1549-BRAF fusion transcripts in formalin-fixed paraffin-embedded pediatric low-grade gliomas.

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2012: Andrew S Chi; William T Curry; Dora Dias-Santagata; Leif Ellisen; Keith L Ligon; David N Louis; Charles D Stiles; Daphne L Wang; Patrick Y Wen; Tracy T Batchelor; Darrell Borger; A John Iafrate
Prospective, high-throughput molecular profiling of human gliomas.
Journal of neuro-oncology 2012;110(1):89-98.
2012: Jing Zhou; Charles D Stiles
Asleep at the switch: MEK kinases control transit to gliogenesis in developing cortex.
Neuron 2012;75(6):940-2.
2011: Yongji Tian; Natalie Vena; Jennifer A Chan; Justin M Craig; Levi A Garraway; Stewart Goldman; Mark W Kieran; Azra H Ligon; Neal I Lindeman; Janina A Longtine; Laura E MacConaill; Madeha Mahmoud; Memet Ozek; Veena Rajaram; Benjamin E Rich; Sandro Santagata; AYDIN SAV; Charles D Stiles; Hala Taha; Keith L Ligon
Detection of KIAA1549-BRAF fusion transcripts in formalin-fixed paraffin-embedded pediatric low-grade gliomas.
The Journal of molecular diagnostics : JMD 2011;13(6):669-77.
2011: Shwetal Mehta; Emmanuelle Huillard; Santosh kesari; Cecile L Maire; Diane Golebiowski; Emily P Harrington; John A Alberta; Michael F Kane; Matthew Theisen; Keith L Ligon; David H Rowitch; Charles D Stiles
The central nervous system-restricted transcription factor Olig2 opposes p53 responses to genotoxic damage in neural progenitors and malignant glioma.
Cancer cell 2011;19(3):359-71.
2009: Hui Fu; Jun Cai; Hans Clevers; Eva Fast; Susan Gray; Rachel Greenberg; Mukesh K Jain; Qiufu Ma; Mengsheng Qiu; David H Rowitch; Christopher M Taylor; Charles D Stiles
A genome-wide screen for spatially restricted expression patterns identifies transcription factors that regulate glial development.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(36):11399-408.
2009: Claire Sauvageot; Jessica Leigh Weatherbee; Santosh kesari; Susan Elizabeth Winters; Jessica Barnes; Jamie Dellagatta; Naren Ramakrishna; Charles D Stiles; Andrew L Kung; Mark W Kieran; Patrick Y Wen
Efficacy of the HSP90 inhibitor 17-AAG in human glioma cell lines and tumorigenic glioma stem cells.
Neuro-oncology 2009;11(2):109-21.
2008: Charles D Stiles; David H Rowitch
Glioma stem cells: a midterm exam.
Neuron 2008;58(6):832-46.
2007: Claire Sauvageot; Santosh kesari; Charles D Stiles
Molecular pathogenesis of adult brain tumors and the role of stem cells.
Neurologic clinics 2007;25(4):891-924, vii.
2007: Santosh kesari; Laurie Jackson-Grusby; Charles D Stiles
"Smad"eningly erratic: target gene methylation determines whether TGFbeta promotes or suppresses malignant glioma.
Developmental cell 2007;12(3):324-5.
2007: Keith L Ligon; Emmanuelle Huillard; Shwetal Mehta; Santosh kesari; Hongye Liu; John A Alberta; Robert M Bachoo; Michael Kane; David N Louis; Ronald A DePinho; David J Anderson; Charles D Stiles; David H Rowitch
Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma.
Neuron 2007;53(4):503-17.
2006: Patrick Y Wen; W K Alfred Yung; Kathleen R Lamborn; Patricia Dahia; Yanfeng Wang; Bin Peng; Lauren E Abrey; Jeffrey Raizer; Timothy F Cloughesy; Karen Fink; Mark Gilbert; Susan Chang; Larry Junck; David Schiff; Frank Lieberman; Howard A Fine; Minesh Mehta; H Ian Robins; Lisa De Angelis; Morris D Groves; Vinay K Puduvalli; Victor Levin; Charles Conrad; Elizabeth A Maher; Kenneth Aldape; Michael Hayes; Laurie Letvak; Merrill J Egorin; Renaud Capdeville; Richard S. Kaplan; Anthony J Murgo; Charles D Stiles; Michael D Prados
Phase I/II study of imatinib mesylate for recurrent malignant gliomas: North American Brain Tumor Consortium Study 99-08.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(16):4899-907.
2006: Santosh kesari; Charles D Stiles
The bad seed: PDGF receptors link adult neural progenitors to glioma stem cells.
Neuron 2006;51(2):151-3.
2006: Keith L Ligon; Santosh kesari; Masaaki Kitada; Tao Sun; Heather A Arnett; John A Alberta; David J Anderson; Charles D Stiles; David H Rowitch
Development of NG2 neural progenitor cells requires Olig gene function.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(20):7853-8.
2006: Tao Sun; Brian P Hafler; Sovann Kaing; Masaaki Kitada; Keith L Ligon; Hans R Widlund; Dong-In Yuk; Charles D Stiles; David H Rowitch
Evidence for motoneuron lineage-specific regulation of Olig2 in the vertebrate neural tube.
Developmental biology 2006;292(1):152-64.
2006: Santosh kesari; Naren Ramakrishna; Claire Sauvageot; Charles D Stiles; Patrick Y Wen
Targeted molecular therapy of malignant gliomas.
Current oncology reports 2006;8(1):58-70.
2005: Patricia Dahia; Ke Hao; John J Rogus; Christian Colin; Miguel Angel Pujana; Ken Ross; Danielle Magoffin; Neil Aronin; Alberto Cascon; César Y Hayashida; Cheng Li; sergio toledo; Charles D Stiles
Novel pheochromocytoma susceptibility loci identified by integrative genomics.
Cancer research 2005;65(21):9651-8.
2005: Patricia Dahia; Kenneth N Ross; Matthew E Wright; César Y Hayashida; Sandro Santagata; Marta Barontini; Andrew L Kung; Gabriela Sanso; James F Powers; Arthur S Tischler; Richard A Hodin; Shannon Heitritter; Francis Moore; Robert Dluhy; Julie Ann Sosa; I Tolgay Ocal; Diana E Benn; Deborah J Marsh; Bruce G Robinson; Katherine Schneider; Judy E Garber; Seth M Arum; Marta Korbonits; Ashley Grossman; Pascal Pigny; sergio toledo; Vania Nosé; Cheng Li; Charles D Stiles
A HIF1alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas.
PLoS genetics 2005;1(1):72-80.
2005: Santosh kesari; Naren Ramakrishna; Claire Sauvageot; Charles D Stiles; Patrick Y Wen
Targeted molecular therapy of malignant gliomas.
Current neurology and neuroscience reports 2005;5(3):186-97.
2005: Adrienne E McKee; Emmanuel Minet; Charlene A. Stern; Shervin Riahi; Charles D Stiles; Pamela A Silver
A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.
BMC developmental biology 2005;5():14.
2005: Claire Sauvageot; Patricia Dahia; Ovidiu Lipan; John K Park; Mi-Sook Chang; John A Alberta; Charles D Stiles
Distinct temporal genetic signatures of neurogenic and gliogenic cues in cortical stem cell cultures.
Journal of neurobiology 2005;62(1):121-33.
2004: Paul A Gray; Hui Fu; Ping Luo; Qing Zhao; Jing Yu; Annette Ferrari; Toyoaki Tenzen; Dong-In Yuk; Eric F Tsung; Zhaohui Cai; John A Alberta; Le-Ping Cheng; Yang Liu; Jan M Stenman; Michael T Valerius; Nathan Billings; Haesun A Kim; Michael E Greenberg; Andrew P McMahon; David H Rowitch; Charles D Stiles; Qiufu Ma
Mouse brain organization revealed through direct genome-scale TF expression analysis.
Science (New York, N.Y.) 2004;306(5705):2255-7.
2004: Heather A Arnett; Stephen P J Fancy; John A Alberta; Chao Zhao; Sheila R Plant; Sovann Kaing; Cedric S Raine; David H Rowitch; Robin J M Franklin; Charles D Stiles
bHLH transcription factor Olig1 is required to repair demyelinated lesions in the CNS.
Science (New York, N.Y.) 2004;306(5704):2111-5.
2004: Keith L Ligon; John A Alberta; Alvin T Kho; Jennifer Weiss; Mary R Kwaan; Catherine L Nutt; David N Louis; Charles D Stiles; David H Rowitch
The oligodendroglial lineage marker OLIG2 is universally expressed in diffuse gliomas.
Journal of neuropathology and experimental neurology 2004;63(5):499-509.
2003: Angela Bithell; John A Alberta; Fraser Hornby; Charles D Stiles; Brenda P Williams
Expression of the guanine nucleotide exchange factor, mr-gef, is regulated during the differentiation of specific subsets of telencephalic neurons.
Brain research. Developmental brain research 2003;146(1-2):107-18.
2003: Charles D Stiles
Lost in space: misregulated positional cues create tripotent neural progenitors in cell culture.
Neuron 2003;40(3):447-9.
2003: Tao Sun; Hualing Dong; Lizi Wu; Michael Kane; David H Rowitch; Charles D Stiles
Cross-repressive interaction of the Olig2 and Nkx2.2 transcription factors in developing neural tube associated with formation of a specific physical complex.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(29):9547-56.
2003: Sarah E Ross; Michael E Greenberg; Charles D Stiles
Basic helix-loop-helix factors in cortical development.
Neuron 2003;39(1):13-25.
2002: Anita Bhattacharyya; Fiona L Watson; Scott L Pomeroy; Yanzhen Z Zhang; Charles D Stiles; Rosalind A Segal
High-resolution imaging demonstrates dynein-based vesicular transport of activated Trk receptors.
Journal of neurobiology 2002;51(4):302-12.
2002: Claire Sauvageot; Charles D Stiles
Molecular mechanisms controlling cortical gliogenesis.
Current opinion in neurobiology 2002;12(3):244-9.
2002: Q Richard Lu; Tao Sun; Zhimin Zhu; Nan Ma; Meritxell Garcia; Charles D Stiles; David H Rowitch
Common developmental requirement for Olig function indicates a motor neuron/oligodendrocyte connection.
Cell 2002;109(1):75-86.
2001: John A Alberta; S K Park; J Mora; Dong-In Yuk; I Pawlitzky; P Iannarelli; T Vartanian; Charles D Stiles; David H Rowitch
Sonic hedgehog is required during an early phase of oligodendrocyte development in mammalian brain.
Molecular and cellular neurosciences 2001;18(4):434-41.
2001: Q Richard Lu; li cai; David H Rowitch; C L Cepko; Charles D Stiles
Ectopic expression of Olig1 promotes oligodendrocyte formation and reduces neuronal survival in developing mouse cortex.
Nature neuroscience 2001;4(10):973-4.
2001: Tao Sun; Yann Echelard; R Lu; Dong-In Yuk; Sovann Kaing; Charles D Stiles; David H Rowitch
Olig bHLH proteins interact with homeodomain proteins to regulate cell fate acquisition in progenitors of the ventral neural tube.
Current biology : CB 2001;11(18):1413-20.
2001: Q Richard Lu; J K Park; E Noll; Jennifer A Chan; John A Alberta; Dong-In Yuk; M G Alzamora; David N Louis; Charles D Stiles; David H Rowitch; Peter Black
Oligodendrocyte lineage genes (OLIG) as molecular markers for human glial brain tumors.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(19):10851-6.
2001: N Tekki-Kessaris; Rachel H Woodruff; AC Hall; W Gaffield; S Kimura; Charles D Stiles; David H Rowitch; William D Richardson
Hedgehog-dependent oligodendrocyte lineage specification in the telencephalon.
Development (Cambridge, England) 2001;128(13):2545-54.
2001: Rachel H Woodruff; N Tekki-Kessaris; Charles D Stiles; David H Rowitch; William D Richardson
Oligodendrocyte development in the spinal cord and telencephalon: common themes and new perspectives.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2001;19(4):379-85.
2001: H A Kim; N Ratner; Thomas M Roberts; Charles D Stiles
Schwann cell proliferative responses to cAMP and Nf1 are mediated by cyclin D1.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(4):1110-6.
2000: T Kilic; John A Alberta; P R Zdunek; Melih Acar; P Iannarelli; Terence O'Reilly; Elisabeth Buchdunger; Peter Black; Charles D Stiles
Intracranial inhibition of platelet-derived growth factor-mediated glioblastoma cell growth by an orally active kinase inhibitor of the 2-phenylaminopyrimidine class.
Cancer research 2000;60(18):5143-50.
2000: W L Wang; M E Healy; Martin Sattler; Shalini Verma; J Lin; Gautam Maulik; Charles D Stiles; James D Griffin; Bruce E Johnson; Ravi Salgia
Growth inhibition and modulation of kinase pathways of small cell lung cancer cell lines by the novel tyrosine kinase inhibitor STI 571.
Oncogene 2000;19(31):3521-8.
2000: H A Kim; Scott L Pomeroy; W Whoriskey; I Pawlitzky; L I Benowitz; Piotr Sicinski; Charles D Stiles; Thomas M Roberts
A developmentally regulated switch directs regenerative growth of Schwann cells through cyclin D1.
Neuron 2000;26(2):405-16.
2000: Q Richard Lu; Dong-In Yuk; John A Alberta; Z Zhu; I Pawlitzky; Jennifer A Chan; Andrew P McMahon; Charles D Stiles; David H Rowitch
Sonic hedgehog--regulated oligodendrocyte lineage genes encoding bHLH proteins in the mammalian central nervous system.
Neuron 2000;25(2):317-29.
1999: J K Park; Brenda P Williams; John A Alberta; Charles D Stiles
Bipotent cortical progenitor cells process conflicting cues for neurons and glia in a hierarchical manner.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(23):10383-9.
1999: John A Alberta; KR Auger; David Batt; P Iannarelli; G Hwang; H L Elliott; R Duke; Thomas M Roberts; Charles D Stiles
Platelet-derived growth factor stimulation of monocyte chemoattractant protein-1 gene expression is mediated by transient activation of the phosphoinositide 3-kinase signal transduction pathway.
The Journal of biological chemistry 1999;274(43):31062-7.
1999: Fiona L Watson; Marimelia A Porcionatto; Anita Bhattacharyya; Charles D Stiles; Rosalind A Segal
TrkA glycosylation regulates receptor localization and activity.
Journal of neurobiology 1999;39(2):323-36.
1999: John Y H Kim; M E Sutton; D J Lu; T A Cho; Liliana C Goumnerova; Luda Goritchenko; J R Kaufman; K K Lam; Amy L Billet; Nancy J Tarbell; J Wu; J C Allen; Charles D Stiles; Rosalind A Segal; Scott L Pomeroy
Activation of neurotrophin-3 receptor TrkC induces apoptosis in medulloblastomas.
Cancer research 1999;59(3):711-9.
1999: Patricia Dahia; Ricardo Aguiar; John A Alberta; JB Kum; S Caron; Heinz Sill; Deborah J Marsh; Jerome Ritz; Arnold S Freedman; Charles D Stiles; Charis Eng
PTEN is inversely correlated with the cell survival factor Akt/PKB and is inactivated via multiple mechanismsin haematological malignancies.
Human molecular genetics 1999;8(2):185-93.
1998: Charles D Stiles
Cancer of the central nervous system. Review of an AACR special conference in cancer research with the joint section on tumors of the AANS/CNS (San Diego, CA, June 7-11, 1997).
Biochimica et biophysica acta 1998;1377(1):R1-10.
1997: Y K Kwon; A Bhattacharyya; John A Alberta; W V Giannobile; K Cheon; Charles D Stiles; Scott L Pomeroy
Activation of ErbB2 during wallerian degeneration of sciatic nerve.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(21):8293-9.
1997: S M Shamah; John A Alberta; W V Giannobile; A Guha; Y K Kwon; Rona S Carroll; Peter Black; Charles D Stiles
Detection of activated platelet-derived growth factor receptors in human meningioma.
Cancer research 1997;57(18):4141-7.
1997: Anita Bhattacharyya; Fiona L Watson; T A Bradlee; Scott L Pomeroy; Charles D Stiles; Rosalind A Segal
Trk receptors function as rapid retrograde signal carriers in the adult nervous system.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(18):7007-16.
1997: John A Alberta; Charles D Stiles
Phosphorylation-directed antibodies in high-flux screens for compounds that modulate signal transduction.
BioTechniques 1997;23(3):490-3.
1997: Brenda P Williams; J K Park; John A Alberta; S G Muhlebach; G Y Hwang; Thomas M Roberts; Charles D Stiles
A PDGF-regulated immediate early gene response initiates neuronal differentiation in ventricular zone progenitor cells.
Neuron 1997;18(4):553-62.
1997: K K Reinertsen; R T Bronson; Charles D Stiles; C Wang
Temporal and spatial specificity of PDGF alpha receptor promoter in transgenic mice.
Gene expression 1997;6(5):301-14.
1996: Rosalind A Segal; Anita Bhattacharyya; L A Rua; John A Alberta; R M Stephens; D R Kaplan; Charles D Stiles
Differential utilization of Trk autophosphorylation sites.
The Journal of biological chemistry 1996;271(33):20175-81.
1996: R R Freter; John A Alberta; G Y Hwang; A L Wrentmore; Charles D Stiles
Platelet-derived growth factor induction of the immediate-early gene MCP-1 is mediated by NF-kappaB and a 90-kDa phosphoprotein coactivator.
The Journal of biological chemistry 1996;271(29):17417-24.
1995: Leda Raptis; Heather L Brownell; S K Liu; Kevin L Firth; L W MacKenzie; Charles D Stiles; John A Alberta
Applications of electroporation of adherent cells in situ, on a partly conductive slide.
Molecular biotechnology 1995;4(2):129-38.
1995: Rosalind A Segal; Scott L Pomeroy; Charles D Stiles
Axonal growth and fasciculation linked to differential expression of BDNF and NT3 receptors in developing cerebellar granule cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(7 Pt 1):4970-81.
1995: A Guha; D Glowacka; R Carroll; K Dashner; Peter Black; Charles D Stiles
Expression of platelet derived growth factor and platelet derived growth factor receptor mRNA in a glioblastoma from a patient with Li-Fraumeni syndrome.
Journal of neurology, neurosurgery, and psychiatry 1995;58(6):711-4.
1995: A Guha; K Dashner; Peter Black; J A Wagner; Charles D Stiles
Expression of PDGF and PDGF receptors in human astrocytoma operation specimens supports the existence of an autocrine loop.
International journal of cancer. Journal international du cancer 1995;60(2):168-73.
1995: S M Shamah; Charles D Stiles
Transdominant negative mutations.
Methods in enzymology 1995;254():565-76.
1995: R R Freter; John A Alberta; K K Lam; Charles D Stiles
A new platelet-derived growth factor-regulated genomic element which binds a serine/threonine phosphoprotein mediates induction of the slow immediate-early gene MCP-1.
Molecular and cellular biology 1995;15(1):315-25.
1995: Leda Raptis; S K Liu; Kevin L Firth; Charles D Stiles; John A Alberta
Electroporation of peptides into adherent cells in situ.
BioTechniques 1995;18(1):104, 106, 108, 110 passim.
1994: Rosalind A Segal; Liliana C Goumnerova; Y K Kwon; Charles D Stiles; Scott L Pomeroy
Expression of the neurotrophin receptor TrkC is linked to a favorable outcome in medulloblastoma.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(26):12867-71.
1994: C Wang; Charles D Stiles
Platelet-derived growth factor alpha receptor gene expression: isolation and characterization of the promoter and upstream regulatory elements.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(15):7061-5.
1994: John A Alberta; K Rundell; Charles D Stiles
Identification of an activity that interacts with the 3'-untranslated region of c-myc mRNA and the role of its target sequence in mediating rapid mRNA degradation.
The Journal of biological chemistry 1994;269(6):4532-8.
1993: S M Shamah; Charles D Stiles; A Guha
Dominant-negative mutants of platelet-derived growth factor revert the transformed phenotype of human astrocytoma cells.
Molecular and cellular biology 1993;13(12):7203-12.
1993: C Wang; Charles D Stiles
Regulation of platelet-derived growth factor A messenger RNA translation in differentiating F9 teratocarcinoma cells.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1993;4(10):871-7.
1993: H S Mudhar; R A Pollock; C Wang; Charles D Stiles; William D Richardson
PDGF and its receptors in the developing rodent retina and optic nerve.
Development (Cambridge, England) 1993;118(2):539-52.
1993: S D Jones; L Ho; J C Smith; C Yordan; Charles D Stiles; Mark Mercola
The Xenopus platelet-derived growth factor alpha receptor: cDNA cloning and demonstration that mesoderm induction establishes the lineage-specific pattern of ligand and receptor gene expression.
Developmental genetics 1993;14(3):185-93.
1992: R R Freter; J C Irminger; J A Porter; S D Jones; Charles D Stiles
A novel 7-nucleotide motif located in 3' untranslated sequences of the immediate-early gene set mediates platelet-derived growth factor induction of the JE gene.
Molecular and cellular biology 1992;12(12):5288-300.
1992: S L Palmieri; J Payne; Charles D Stiles; J D Biggers; Mark Mercola
Expression of mouse PDGF-A and PDGF alpha-receptor genes during pre- and post-implantation development: evidence for a developmental shift from an autocrine to a paracrine mode of action.
Mechanisms of development 1992;39(3):181-91.
1992: R J Epstein; Brian J Druker; Thomas M Roberts; Charles D Stiles
Synthetic phosphopeptide immunogens yield activation-specific antibodies to the c-erbB-2 receptor.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(21):10435-9.
1992: R J Epstein; Brian J Druker; J C Irminger; S D Jones; Thomas M Roberts; Charles D Stiles
Extracellular calcium mimics the actions of platelet-derived growth factor on mouse fibroblasts.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1992;3(3):157-64.
1992: C Wang; S M Shamah; Charles D Stiles
Recombinant PDGF from lower vertebrates: receptor binding and immunochemical analysis with metabolically labeled growth factor.
Growth factors (Chur, Switzerland) 1992;7(4):279-88.
1991: P C Yaeger; Charles D Stiles; Barrett J Rollins
Human keratinocyte growth-promoting activity on the surface of fibroblasts.
Journal of cellular physiology 1991;149(1):110-6.
1991: D A Stephenson; Mark Mercola; E Anderson; C Y Wang; Charles D Stiles; D F Bowen-Pope; Verne M Chapman
Platelet-derived growth factor receptor alpha-subunit gene (Pdgfra) is deleted in the mouse patch (Ph) mutation.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(1):6-10.
1990: Mark Mercola; P L Deininger; S M Shamah; J Porter; C Y Wang; Charles D Stiles
Dominant-negative mutants of a platelet-derived growth factor gene.
Genes & development 1990;4(12B):2333-41.
1990: C Wang; J Kelly; D F Bowen-Pope; Charles D Stiles
Retinoic acid promotes transcription of the platelet-derived growth factor alpha-receptor gene.
Molecular and cellular biology 1990;10(12):6781-4.
1990: R J Epstein; Brian J Druker; Thomas M Roberts; Charles D Stiles
Modulation of a Mr 175,000 c-neu receptor isoform in G8/DHFR cells by serum starvation.
The Journal of biological chemistry 1990;265(18):10746-51.
1990: Mark Mercola; C Y Wang; J Kelly; C Brownlee; L Jackson-Grusby; Charles D Stiles; D Bowen-Pope
Selective expression of PDGF A and its receptor during early mouse embryogenesis.
Developmental biology 1990;138(1):114-22.
1990: Mariano A Garcia-Blanco; J A Porter; E D Morrison; Charles D Stiles
The beta-interferon-mediated antimitogenic state resembles the anti-viral state.
Oncogene research 1990;5(4):323-8.
1989: D J Hall; C Brownlee; Charles D Stiles
Interleukin-1 is a potent regulator of JE and KC gene expression in quiescent BALB/c fibroblasts.
Journal of cellular physiology 1989;141(1):154-9.
1989: Barrett J Rollins; T M O'Connell; Gary G Bennett; L E Burton; Charles D Stiles; J G Rheinwald
Environment-dependent growth inhibition of human epidermal keratinocytes by recombinant human transforming growth factor-beta.
Journal of cellular physiology 1989;139(3):455-62.
1989: D J Hall; S D Jones; D R Kaplan; Malcolm Whitman; Barrett J Rollins; Charles D Stiles
Evidence for a novel signal transduction pathway activated by platelet-derived growth factor and by double-stranded RNA.
Molecular and cellular biology 1989;9(4):1705-13.
1989: P Oquendo; John A Alberta; D Z Wen; J L Graycar; R Derynck; Charles D Stiles
The platelet-derived growth factor-inducible KC gene encodes a secretory protein related to platelet alpha-granule proteins.
The Journal of biological chemistry 1989;264(7):4133-7.
1989: Mariano A Garcia-Blanco; Peter Lengyel; E Morrison; C Brownlee; Charles D Stiles; M Rutherford; G Hannigan; B R Williams
Regulation of 2',5'-oligoadenylate synthetase gene expression by interferons and platelet-derived growth factor.
Molecular and cellular biology 1989;9(3):1060-8.
1989: Barrett J Rollins; Charles D Stiles
Serum-inducible genes.
Advances in cancer research 1989;53():1-32.
1989: D J Hall; John A Alberta; Charles D Stiles
Labile repressors are involved in the transcriptional control of PDGF-responsive genes.
Oncogene research 1989;4(3):177-84.
1988: Mark Mercola; D A Melton; Charles D Stiles
Platelet-derived growth factor A chain is maternally encoded in Xenopus embryos.
Science (New York, N.Y.) 1988;241(4870):1223-5.
1988: P R Burd; Barrett J Rollins; S D Wilson; P R Billings; Charles D Stiles; Martin E Dorf
Comparison of fibroblast and T-cell activation genes.
Cellular immunology 1988;115(2):481-3.
1988: Barrett J Rollins; E D Morrison; Charles D Stiles
Cloning and expression of JE, a gene inducible by platelet-derived growth factor and whose product has cytokine-like properties.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(11):3738-42.
1988: Mark Mercola; Charles D Stiles
Growth factor superfamilies and mammalian embryogenesis.
Development (Cambridge, England) 1988;102(3):451-60.
1988: Barrett J Rollins; Charles D Stiles
Regulation of c-myc and c-fos proto-oncogene expression by animal cell growth factors.
In vitro cellular & developmental biology : journal of the Tissue Culture Association 1988;24(2):81-4.
1988: Barrett J Rollins; Charles D Stiles
Molecular regulation of growth control: implications for wound healing.
Progress in clinical and biological research 1988;266():19-22.
1988: S D Jones; D J Hall; Barrett J Rollins; Charles D Stiles
Platelet-derived growth factor generates at least two distinct intracellular signals that modulate gene expression.
Cold Spring Harbor symposia on quantitative biology 1988;53 Pt 1():531-6.
1987: Barrett J Rollins; E D Morrison; Charles D Stiles
A cell-cycle constraint on the regulation of gene expression by platelet-derived growth factor.
Science (New York, N.Y.) 1987;238(4831):1269-71.
1987: D J Hall; Charles D Stiles
Platelet-derived growth factor-inducible genes respond differentially to at least two distinct intracellular second messengers.
The Journal of biological chemistry 1987;262(31):15302-8.
1987: P Zumstein; Charles D Stiles
Molecular cloning of gene sequences that are regulated by insulin-like growth factor I.
The Journal of biological chemistry 1987;262(23):11252-60.
1987: J Zullo; Charles D Stiles; R L Garcea
Regulation of c-myc and c-fos mRNA levels by polyomavirus: distinct roles for the capsid protein VP1 and the viral early proteins.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(5):1210-4.
1987: B H Cochran; P Zumstein; J Zullo; Barrett J Rollins; Mark Mercola; Charles D Stiles
Differential colony hybridization: molecular cloning from a zero data base.
Methods in enzymology 1987;147():64-85.
1986: Carolyn W Gibson; S R Rittling; R R Hirschhorn; Leszek Kaczmarek; B Calabretta; Charles D Stiles; Renato Baserga
Cell cycle dependent genes inducible by different mitogens in cells from different species.
Molecular and cellular biochemistry 1986;71(1):61-9.
1985: J N Zullo; B H Cochran; A S Huang; Charles D Stiles
Platelet-derived growth factor and double-stranded ribonucleic acids stimulate expression of the same genes in 3T3 cells.
Cell 1985;43(3 Pt 2):793-800.
1985: Charles D Stiles
The biological role of oncogenes--insights from platelet-derived growth factor: Rhoads Memorial Award lecture.
Cancer research 1985;45(11 Pt 1):5215-8.
1985: M Callahan; B H Cochran; Charles D Stiles
The PDGF-inducible 'competence genes': intracellular mediators of the mitogenic response.
Ciba Foundation symposium 1985;116():87-97.
1984: B H Cochran; J Zullo; Inder M Verma; Charles D Stiles
Expression of the c-fos gene and of an fos-related gene is stimulated by platelet-derived growth factor.
Science (New York, N.Y.) 1984;226(4678):1080-2.
1984: Charles D Stiles
Autocrine control of growth?
Nature 1984;311(5987):604-5.
1984: Hugo A Armelin; M C Armelin; K Kelly; T Stewart; P Leder; B H Cochran; Charles D Stiles
Functional role for c-myc in mitogenic response to platelet-derived growth factor.
Nature 1984;310(5979):655-60.
1984: B J Bockus; Charles D Stiles
Regulation of cytoskeletal architecture by platelet-derived growth factor, insulin and epidermal growth factor.
Experimental cell research 1984;153(1):186-97.
1984: B J Bockus; C D Scher; Charles D Stiles
Use of defined media for analysis of the action of platelet-derived growth factor on fibroblasts.
Progress in clinical and biological research 1984;154():133-41.
1984: S L Hendrickson; B H Cochran; A C Reffel; Charles D Stiles
Regulation of gene expression by serum and serum growth factors.
Symposium on Fundamental Cancer Research 1984;37():71-85.
1984: K Kelly; B Cochran; Charles D Stiles; P Leder
The regulation of c-myc by growth signals.
Current topics in microbiology and immunology 1984;113():117-26.
1983: K Kelly; B H Cochran; Charles D Stiles; P Leder
Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor.
Cell 1983;35(3 Pt 2):603-10.
1983: B H Cochran; A C Reffel; Charles D Stiles
Molecular cloning of gene sequences regulated by platelet-derived growth factor.
Cell 1983;33(3):939-47.
1983: Charles D Stiles
The molecular biology of platelet-derived growth factor.
Cell 1983;33(3):653-5.
1983: J P Singh; M A Chaikin; Warren Pledger; C D Scher; Charles D Stiles
Persistence of the mitogenic response to platelet-derived growth factor (competence) does not reflect a long-term interaction between the growth factor and the target cell.
The Journal of cell biology 1983;96(5):1497-502.
1982: J P Singh; M A Chaikin; Charles D Stiles
Phylogenetic analysis of platelet-derived growth factor by radio-receptor assay.
The Journal of cell biology 1982;95(2 Pt 1):667-71.
1982: J C Smith; J P Singh; Jay Lillquist; D S Goon; Charles D Stiles
Growth factors adherent to cell substrate are mitogenically active in situ.
Nature 1982;296(5853):154-6.
1981: B H Cochran; Jay Lillquist; Charles D Stiles
Post-transcriptional control of protein synthesis in Balb/c-3T3 cells by platelet-derived growth factor and platelet-poor plasma.
Journal of cellular physiology 1981;109(3):429-38.
1981: J C Smith; Charles D Stiles
Cytoplasmic transfer of the mitogenic response to platelet-derived growth factor.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(7):4363-7.
1980: Christopher Frantz; Charles D Stiles; Warren Pledger; C D Scher
Effect of ouabain on growth regulation by serum components in Balb/c-3T3 cells: inhibition of entry into S phase by decreased protein synthesis.
Journal of cellular physiology 1980;105(3):439-48.
1980: C D Scher; J I Farhi; R I Handin; D R Kaplan; Jay Lillquist; K McGovern; Charles D Stiles
Initiation of cell replication by cationic polypeptide hormones.
Society of General Physiologists series 1980;35():39-54.
1980: Charles D Stiles; Warren Pledger; R W Tucker; R G Martin; C D Scher
Regulation of the Balb/c-3T3 cell cycle-effects of growth factors.
Journal of supramolecular structure 1980;13(4):489-99.
1980: R G Martin; V P Setlow; A B Chepelinsky; R Seif; A M Lewis; C D Scher; Charles D Stiles; Jesús Avila
Roles of the T antigens in transformation by SV40.
Cold Spring Harbor symposia on quantitative biology 1980;44 Pt 1,():311-24.