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David Stillman

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Chemicals & Drugs

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Saccharomyces cerevisiae

Physiology

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Publications

TOP 3
Shinya Takahata; Yaxin Yu; David J Stillman
Repressive chromatin affects factor binding at yeast HO (homothallic switching) promoter.
Laura McCullough; Aileen Olsen; Robert Rawlins; David J Stillman; Hua Xin; Tim Formosa
Insight into the mechanism of nucleosome reorganization from histone mutants that suppress defects in the FACT histone chaperone.
David J Stillman
Nhp6: a small but powerful effector of chromatin structure in Saccharomyces cerevisiae.

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All Publications

2011: Shinya Takahata; Yaxin Yu; David J Stillman
Repressive chromatin affects factor binding at yeast HO (homothallic switching) promoter.
The Journal of biological chemistry 2011;286(40):34809-19.
2011: Laura McCullough; Aileen Olsen; Robert Rawlins; David J Stillman; Hua Xin; Tim Formosa
Insight into the mechanism of nucleosome reorganization from histone mutants that suppress defects in the FACT histone chaperone.
Genetics 2011;188(4):835-46.
2010: David J Stillman
Nhp6: a small but powerful effector of chromatin structure in Saccharomyces cerevisiae.
Biochimica et biophysica acta 2010;1799(1-2):175-80.
2009: Shinya Takahata; Yaxin Yu; David J Stillman
The E2F functional analogue SBF recruits the Rpd3(L) HDAC, via Whi5 and Stb1, and the FACT chromatin reorganizer, to yeast G1 cyclin promoters.
The EMBO journal 2009;28(21):3378-89.
2009: Santhi Pondugula; Daniel Neef; Warren P Voth; Russell P Darst; Archana Dhasarathy; M Megan Reynolds; Shinya Takahata; David J Stillman; Michael P Kladde
Coupling phosphate homeostasis to cell cycle-specific transcription: mitotic activation of Saccharomyces cerevisiae PHO5 by Mcm1 and Forkhead proteins.
Molecular and cellular biology 2009;29(18):4891-905.
2009: Hua Xin; Shinya Takahata; Mary Blanksma; Laura McCullough; David J Stillman; Tim Formosa
yFACT induces global accessibility of nucleosomal DNA without H2A-H2B displacement.
Molecular cell 2009;35(3):365-76.
2009: Shinya Takahata; Yaxin Yu; David J Stillman
FACT and Asf1 regulate nucleosome dynamics and coactivator binding at the HO promoter.
Molecular cell 2009;34(4):405-15.
2008: Emily J Parnell; David J Stillman
Getting a transcription factor to only one nucleus following mitosis.
PLoS biology 2008;6(9):e229.
2008: Debabrata Biswas; Shinya Takahata; David J Stillman
Different genetic functions for the Rpd3(L) and Rpd3(S) complexes suggest competition between NuA4 and Rpd3(S).
Molecular and cellular biology 2008;28(14):4445-58.
2008: Mohammed Sbia; Emily J Parnell; Yaxin Yu; Aileen E Olsen; Kelsi L Kretschmann; Warren P Voth; David J Stillman
Regulation of the yeast Ace2 transcription factor during the cell cycle.
The Journal of biological chemistry 2008;283(17):11135-45.
2008: Andrew P VanDemark; Hua Xin; Laura McCullough; Robert Rawlins; Shayla Bentley; Annie Heroux; David J Stillman; Christopher P Hill; Tim Formosa
Structural and functional analysis of the Spt16p N-terminal domain reveals overlapping roles of yFACT subunits.
The Journal of biological chemistry 2008;283(8):5058-68.
2008: Debabrata Biswas; Shinya Takahata; Hua Xin; Rinku Dutta-Biswas; Yaxin Yu; Tim Formosa; David J Stillman
A role for Chd1 and Set2 in negatively regulating DNA replication in Saccharomyces cerevisiae.
Genetics 2008;178(2):649-59.
2007: Warren P Voth; Yaxin Yu; Shinya Takahata; Kelsi L Kretschmann; Jason Dillon Lieb; Rebecca L Parker; Brett Milash; David J Stillman
Forkhead proteins control the outcome of transcription factor binding by antiactivation.
The EMBO journal 2007;26(20):4324-34.
2007: Debabrata Biswas; Rinku Dutta-Biswas; David J Stillman
Chd1 and yFACT act in opposition in regulating transcription.
Molecular and cellular biology 2007;27(18):6279-87.
2006: Debabrata Biswas; Rinku Dutta-Biswas; Doyel Mitra; Yoichiro Shibata; Brian D Strahl; Tim Formosa; David J Stillman
Opposing roles for Set2 and yFACT in regulating TBP binding at promoters.
The EMBO journal 2006;25(19):4479-89.
2006: Doyel Mitra; Emily J Parnell; Jack W Landon; Yaxin Yu; David J Stillman
SWI/SNF binding to the HO promoter requires histone acetylation and stimulates TATA-binding protein recruitment.
Molecular and cellular biology 2006;26(11):4095-110.
2006: Debabrata Biswas; Yaxin Yu; Doyel Mitra; David J Stillman
Genetic interactions between Nhp6 and Gcn5 with Mot1 and the Ccr4-Not complex that regulate binding of TATA-binding protein in Saccharomyces cerevisiae.
Genetics 2006;172(2):837-49.
2005: Debabrata Biswas; Yaxin Yu; Matthew Prall; Tim Formosa; David J Stillman
The yeast FACT complex has a role in transcriptional initiation.
Molecular and cellular biology 2005;25(14):5812-22.
2005: Warren P Voth; Aileen E Olsen; Mohammed Sbia; Karen H Freedman; David J Stillman
ACE2, CBK1, and BUD4 in budding and cell separation.
Eukaryotic cell 2005;4(6):1018-28.
2004: Debabrata Biswas; Anthony N Imbalzano; Peter Eriksson; Yaxin Yu; David J Stillman
Role for Nhp6, Gcn5, and the Swi/Snf complex in stimulating formation of the TATA-binding protein-TFIIA-DNA complex.
Molecular and cellular biology 2004;24(18):8312-21.
2004: Peter Eriksson; Debabrata Biswas; Yaxin Yu; James M Stewart; David J Stillman
TATA-binding protein mutants that are lethal in the absence of the Nhp6 high-mobility-group protein.
Molecular and cellular biology 2004;24(14):6419-29.
2004: Amanda J Bird; Elizabeth Blankman; David J Stillman; David J Eide; Dennis R Winge
The Zap1 transcriptional activator also acts as a repressor by binding downstream of the TATA box in ZRT2.
The EMBO journal 2004;23(5):1123-32.
2004: Peter Eriksson; Lance R Thomas; Andrew Thorburn; David J Stillman
pRS yeast vectors with a LYS2 marker.
BioTechniques 2004;36(2):212-3.
2003: Warren P Voth; David J Stillman
Changes in developmental state: demolish the old to construct the new.
Genes & development 2003;17(18):2201-4.
2003: Warren P Voth; Yi Wei Jiang; David J Stillman
New 'marker swap' plasmids for converting selectable markers on budding yeast gene disruptions and plasmids.
Yeast (Chichester, England) 2003;20(11):985-93.
2003: Yaxin Yu; Peter Eriksson; Leena T Bhoite; David J Stillman
Regulation of TATA-binding protein binding by the SAGA complex and the Nhp6 high-mobility group protein.
Molecular and cellular biology 2003;23(6):1910-21.
2002: Tim Formosa; Susan Ruone; Melissa D Adams; Aileen E Olsen; Peter Eriksson; Yaxin Yu; Alison R Rhoades; Paul D Kaufman; David J Stillman
Defects in SPT16 or POB3 (yFACT) in Saccharomyces cerevisiae cause dependence on the Hir/Hpc pathway: polymerase passage may degrade chromatin structure.
Genetics 2002;162(4):1557-71.
2002: Leena T Bhoite; Jason M Allen; Emily Garcia; Lance R Thomas; I David Gregory; Warren P Voth; Kristen Whelihan; Ronda J Rolfes; David J Stillman
Mutations in the pho2 (bas2) transcription factor that differentially affect activation with its partner proteins bas1, pho4, and swi5.
The Journal of biological chemistry 2002;277(40):37612-8.
2002: Charles Hannum; Olga I Kulaeva; Helen Sun; Jennifer L Urbanowski; Ashley Wendus; David J Stillman; Ronda J Rolfes
Functional mapping of Bas2. Identification of activation and Bas1-interaction domains.
The Journal of biological chemistry 2002;277(37):34003-9.
2002: Lance R Thomas; David J Stillman; Andrew Thorburn
Regulation of Fas-associated death domain interactions by the death effector domain identified by a modified reverse two-hybrid screen.
The Journal of biological chemistry 2002;277(37):34343-8.
2002: Masahiko Harata; Yan Zhang; David J Stillman; Daisuke Matsui; Yukako Oma; Katsuhiko Nishimori; Ryo Mochizuki
Correlation between chromatin association and transcriptional regulation for the Act3p/Arp4 nuclear actin-related protein of Saccharomyces cerevisiae.
Nucleic acids research 2002;30(8):1743-50.
2001: HJ McBride; Alok Kumar Sil; Vivien Measday; Yaxin Yu; Jason Moffat; M E Maxon; I Herskowitz; Brenda Andrews; David J Stillman
The protein kinase Pho85 is required for asymmetric accumulation of the Ash1 protein in Saccharomyces cerevisiae.
Molecular microbiology 2001;42(2):345-53.
2001: Leena T Bhoite; Yaxin Yu; David J Stillman
The Swi5 activator recruits the Mediator complex to the HO promoter without RNA polymerase II.
Genes & development 2001;15(18):2457-69.
2001: Tim Formosa; Peter Eriksson; Jacqueline Wittmeyer; J Ginn; Yaxin Yu; David J Stillman
Spt16-Pob3 and the HMG protein Nhp6 combine to form the nucleosome-binding factor SPN.
The EMBO journal 2001;20(13):3506-17.
2001: Warren P Voth; J D Richards; Janet M Shaw; David J Stillman
Yeast vectors for integration at the HO locus.
Nucleic acids research 2001;29(12):E59-9.
2000: A D Watson; Diane G Edmondson; James R Bone; Y Mukai; Y Yu; W Du; David J Stillman; SY Roth
Ssn6-Tup1 interacts with class I histone deacetylases required for repression.
Genes & development 2000;14(21):2737-44.
2000: Masahiko Harata; Yukako Oma; T Tabuchi; Y Zhang; David J Stillman; Shigeki Mizuno
Multiple actin-related proteins of Saccharomyces cerevisiae are present in the nucleus.
Journal of biochemistry 2000;128(4):665-71.
2000: D Y Zhang; Michael Dorsey; Warren P Voth; Daniel J Carson; Xiao Zeng; David J Stillman; Jun Ma
Intramolecular interaction of yeast TFIIB in transcription control.
Nucleic acids research 2000;28(9):1913-20.
2000: Yaxin Yu; Peter Eriksson; David J Stillman
Architectural transcription factors and the SAGA complex function in parallel pathways to activate transcription.
Molecular and cellular biology 2000;20(7):2350-7.
2000: A Meimoun; T Holtzman; Ziva Weissman; HJ McBride; David J Stillman; G R Fink; Daniel Kornitzer
Degradation of the transcription factor Gcn4 requires the kinase Pho85 and the SCF(CDC4) ubiquitin-ligase complex.
Molecular biology of the cell 2000;11(3):915-27.
2000: Vivien Measday; HJ McBride; Jason Moffat; David J Stillman; Brenda Andrews
Interactions between Pho85 cyclin-dependent kinase complexes and the Swi5 transcription factor in budding yeast.
Molecular microbiology 2000;35(4):825-34.
2000: S Dorland; M L Deegenaars; David J Stillman
Roles for the Saccharomyces cerevisiae SDS3, CBK1 and HYM1 genes in transcriptional repression by SIN3.
Genetics 2000;154(2):573-86.
1999: Masahiko Harata; Yukako Oma; Shigeki Mizuno; Y W Jiang; David J Stillman; Ulrike Wintersberger
The nuclear actin-related protein of Saccharomyces cerevisiae, Act3p/Arp4, interacts with core histones.
Molecular biology of the cell 1999;10(8):2595-605.
1999: HJ McBride; Yaxin Yu; David J Stillman
Distinct regions of the Swi5 and Ace2 transcription factors are required for specific gene activation.
The Journal of biological chemistry 1999;274(30):21029-36.
1998: Leena T Bhoite; David J Stillman
Residues in the Swi5 zinc finger protein that mediate cooperative DNA binding with the Pho2 homeodomain protein.
Molecular and cellular biology 1998;18(11):6436-46.
1998: Diane G Edmondson; Wenzhu Zhang; A Watson; Wenhao Xu; James R Bone; Y Yu; David J Stillman; SY Roth
In vivo functions of histone acetylation/deacetylation in Tup1p repression and Gcn5p activation.
Cold Spring Harbor symposia on quantitative biology 1998;63():459-68.
1997: Margaret M Kasten; David J Stillman
Identification of the Saccharomyces cerevisiae genes STB1-STB5 encoding Sin3p binding proteins.
Molecular & general genetics : MGG 1997;256(4):376-86.
1997: Margaret M Kasten; S Dorland; David J Stillman
A large protein complex containing the yeast Sin3p and Rpd3p transcriptional regulators.
Molecular and cellular biology 1997;17(8):4852-8.
1997: HJ McBride; Robert Brazas; Yaxin Yu; K Nasmyth; David J Stillman
Long-range interactions at the HO promoter.
Molecular and cellular biology 1997;17(5):2669-78.
1997: T Macatee; Y W Jiang; David J Stillman; SY Roth
Global alterations in chromatin accessibility associated with loss of SIN4 function.
Nucleic acids research 1997;25(6):1240-7.
1997: Darrell R Davis; David J Stillman
Altered structure of the DNA duplex recognized by yeast transcription factor Reb1p.
Nucleic acids research 1997;25(3):668-74.
1996: Yaxin Yu; Y W Jiang; R J Wellinger; K Carlson; J M Roberts; David J Stillman
Mutations in the homologous ZDS1 and ZDS2 genes affect cell cycle progression.
Molecular and cellular biology 1996;16(10):5254-63.
1996: Margaret M Kasten; Donald E Ayer; David J Stillman
SIN3-dependent transcriptional repression by interaction with the Mad1 DNA-binding protein.
Molecular and cellular biology 1996;16(8):4215-21.
1996: W Yu; R A Farrell; David J Stillman; Dennis R Winge
Identification of SLF1 as a new copper homeostasis gene involved in copper sulfide mineralization in Saccharomyces cerevisiae.
Molecular and cellular biology 1996;16(5):2464-72.
1996: P R Dohrmann; W P Voth; David J Stillman
Role of negative regulation in promoter specificity of the homologous transcriptional activators Ace2p and Swi5p.
Molecular and cellular biology 1996;16(4):1746-58.
1996: Y W Jiang; David J Stillman
Epigenetic effects on yeast transcription caused by mutations in an actin-related protein present in the nucleus.
Genes & development 1996;10(5):604-19.
1995: Robert Brazas; L T Bhoite; M D Murphy; Yaxin Yu; Y Chen; Deborah W Neklason; David J Stillman
Determining the requirements for cooperative DNA binding by Swi5p and Pho2p (Grf10p/Bas2p) at the HO promoter.
The Journal of biological chemistry 1995;270(49):29151-61.
1995: Yiming Li; S Bjorklund; Y W Jiang; Y J Kim; William Stratton Lane; David J Stillman; Roger D Kornberg
Yeast global transcriptional regulators Sin4 and Rgr1 are components of mediator complex/RNA polymerase II holoenzyme.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(24):10864-8.
1995: Y W Jiang; P R Dohrmann; David J Stillman
Genetic and physical interactions between yeast RGR1 and SIN4 in chromatin organization and transcriptional regulation.
Genetics 1995;140(1):47-54.
1995: Y W Jiang; David J Stillman
Regulation of HIS4 expression by the Saccharomyces cerevisiae SIN4 transcriptional regulator.
Genetics 1995;140(1):103-14.
1994: H Wang; L Reynolds-Hager; David J Stillman
Genetic interactions between SIN3 mutations and the Saccharomyces cerevisiae transcriptional activators encoded by MCM1, STE12, and SWI1.
Molecular & general genetics : MGG 1994;245(6):675-85.
1994: David J Stillman; S Dorland; Yaxin Yu
Epistasis analysis of suppressor mutations that allow HO expression in the absence of the yeast SW15 transcriptional activator.
Genetics 1994;136(3):781-8.
1993: Robert Brazas; David J Stillman
The Swi5 zinc-finger and Grf10 homeodomain proteins bind DNA cooperatively at the yeast HO promoter.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(23):11237-41.
1993: Robert Brazas; David J Stillman
Identification and purification of a protein that binds DNA cooperatively with the yeast SWI5 protein.
Molecular and cellular biology 1993;13(9):5524-37.
1993: H Wang; David J Stillman
Transcriptional repression in Saccharomyces cerevisiae by a SIN3-LexA fusion protein.
Molecular and cellular biology 1993;13(3):1805-14.
1992: Y W Jiang; David J Stillman
Involvement of the SIN4 global transcriptional regulator in the chromatin structure of Saccharomyces cerevisiae.
Molecular and cellular biology 1992;12(10):4503-14.
1992: M P Mayer; F M Hahn; David J Stillman; C Dale Poulter
Disruption and mapping of IDI1, the gene for isopentenyl diphosphate isomerase in Saccharomyces cerevisiae.
Yeast (Chichester, England) 1992;8(9):743-8.
1992: P R Dohrmann; G Butler; K Tamai; S Dorland; J R Greene; Dennis J Thiele; David J Stillman
Parallel pathways of gene regulation: homologous regulators SWI5 and ACE2 differentially control transcription of HO and chitinase.
Genes & development 1992;6(1):93-104.
1990: H Wang; David J Stillman
In vitro regulation of a SIN3-dependent DNA-binding activity by stimulatory and inhibitory factors.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(24):9761-5.
1990: H Wang; I Clark; P R Nicholson; I Herskowitz; David J Stillman
The Saccharomyces cerevisiae SIN3 gene, a negative regulator of HO, contains four paired amphipathic helix motifs.
Molecular and cellular biology 1990;10(11):5927-36.
1990: H Wang; P R Nicholson; David J Stillman
Identification of a Saccharomyces cerevisiae DNA-binding protein involved in transcriptional regulation.
Molecular and cellular biology 1990;10(4):1743-53.